Homo sapiens

38 known processes

PRDX2

peroxiredoxin 2

(Aliases: TPX1,TDPX1,PRX2,PRP,TSA,MGC4104,NKEFB,PRXII)

PRDX2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.988
multicellular organismal agingGO:001025930.395
Worm
response to oxidative stressGO:00069791210.358
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.346
Human
protein oxidationGO:001815850.345
Human
cellular response to hydrogen peroxideGO:0070301370.300
Human Mouse Worm
regulation of protein processingGO:00706131500.283
Human
lipid metabolic processGO:00066293810.272
ion transmembrane transportGO:00342203380.217
cellular amino acid metabolic processGO:00065201160.216
reactive oxygen species metabolic processGO:0072593750.196
mitochondrion organizationGO:00070051560.192
Human
intrinsic apoptotic signaling pathwayGO:00971931270.192
cellular ketone metabolic processGO:0042180800.191
lipid catabolic processGO:0016042840.180
protein processingGO:00164852260.172
Human
response to reactive oxygen speciesGO:0000302610.166
cellular response to oxidative stressGO:0034599850.157
negative regulation of protein processingGO:00109551420.155
Human
negative regulation of cellular protein metabolic processGO:00322693530.155
Human
regulation of proteolysisGO:00301622930.148
Human
response to hydrogen peroxideGO:0042542400.145
Human Mouse Worm
post embryonic developmentGO:000979120.140
negative regulation of catalytic activityGO:00430863350.139
Human
regulation of apoptotic signaling pathwayGO:20012331750.135
Mouse
cation transportGO:00068123310.132
regulation of endopeptidase activityGO:00525481700.131
Human
cell cycle checkpointGO:00000751170.122
response to inorganic substanceGO:00100351270.121
transmembrane transportGO:00550853990.121
protein maturationGO:00516042330.116
Human
hydrogen transportGO:0006818230.112
positive regulation of cell deathGO:00109422630.108
cellular homeostasisGO:00197251960.104
carboxylic acid biosynthetic processGO:0046394970.102
cellular amine metabolic processGO:0044106410.099
regulation of kinase activityGO:00435493140.097
Human Mouse
cellular response to superoxideGO:007145160.095
cofactor metabolic processGO:0051186870.093
fatty acid metabolic processGO:00066311150.092
small molecule catabolic processGO:0044282920.088
negative regulation of phosphate metabolic processGO:00459362670.087
Human
cellular response to oxygen radicalGO:007145060.086
vitamin metabolic processGO:0006766260.084
regulation of protein localizationGO:00328802960.084
hydrogen peroxide catabolic processGO:0042744130.082
Human Mouse Worm
regulation of proteasomal protein catabolic processGO:0061136870.082
inorganic ion transmembrane transportGO:00986602310.081
apoptotic signaling pathwayGO:00971902680.081
Mouse
ketone catabolic processGO:004218230.079
regulation of protein maturationGO:19033171500.079
Human
monocarboxylic acid metabolic processGO:00327871850.078
negative regulation of transferase activityGO:00513481240.077
Human
negative regulation of protein metabolic processGO:00512483910.076
Human
regulation of cellular amino acid metabolic processGO:000652160.076
negative regulation of endopeptidase activityGO:0010951840.075
Human
purine nucleoside triphosphate catabolic processGO:00091463920.074
regulation of peptidase activityGO:00525471800.073
Human
cellular response to dna damage stimulusGO:00069743790.072
membrane hyperpolarizationGO:006008110.072
regulation of membrane potentialGO:0042391950.067
Human
regulation of cellular response to stressGO:00801352440.066
regulation of cell cycleGO:00517263930.066
response to woundingGO:00096111680.065
Mouse
positive regulation of cell proliferationGO:00082843010.065
Human
determination of adult lifespanGO:000834020.063
Worm
negative regulation of apoptotic signaling pathwayGO:2001234970.062
Mouse
peptidyl cysteine modificationGO:001819890.061
Human
response to axon injuryGO:004867810.061
negative regulation of developmental processGO:00510932470.060
Mouse
regulation of establishment of protein localizationGO:00702012420.060
organonitrogen compound biosynthetic processGO:19015662000.059
regulation of transferase activityGO:00513383550.058
Human Mouse
response to abiotic stimulusGO:00096283360.058
Worm
regulation of cysteine type endopeptidase activityGO:20001161270.057
Human
cellular modified amino acid metabolic processGO:0006575640.056
atp metabolic processGO:00460341760.055
positive regulation of programmed cell deathGO:00430682490.051
cellular component morphogenesisGO:00329893140.051
regulation of neural precursor cell proliferationGO:200017740.051
organic hydroxy compound metabolic processGO:19016151470.051
cellular modified amino acid biosynthetic processGO:0042398150.049
chemical homeostasisGO:00488783060.049
regulation of ion transportGO:00432691890.049
dephosphorylationGO:00163112090.049
cellular response to reactive oxygen speciesGO:0034614500.049
negative regulation of peptidase activityGO:0010466910.047
Human
inorganic cation transmembrane transportGO:00986621940.047
regulation of cellular protein catabolic processGO:1903362960.047
cellular lipid catabolic processGO:0044242650.046
single organism cellular localizationGO:19025803320.045
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.045
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.044
Human
organophosphate catabolic processGO:00464344300.044
regulation of oxidoreductase activityGO:0051341430.044
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.043
Mouse
response to oxygen containing compoundGO:19017003690.043
ribonucleoside triphosphate metabolic processGO:00091994120.042
removal of superoxide radicalsGO:001943060.042
modification dependent macromolecule catabolic processGO:00436322120.042
dopamine biosynthetic processGO:004241640.042
cellular amino acid biosynthetic processGO:0008652300.042
small gtpase mediated signal transductionGO:0007264780.040
neuroblast proliferationGO:000740540.039
alpha amino acid biosynthetic processGO:1901607230.039
regulation of cellular amine metabolic processGO:0033238110.039
ras protein signal transductionGO:0007265730.039
cellular lipid metabolic processGO:00442553030.039
regulation of mitotic cell cycleGO:00073461890.038
carbohydrate derivative biosynthetic processGO:19011372070.038
cell developmentGO:00484683280.038
response to toxic substanceGO:0009636370.037
cytokine productionGO:00018162470.037
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.037
protein modification by small protein conjugationGO:00324463420.036
negative regulation of cell cycle phase transitionGO:1901988890.036
regulation of immune responseGO:00507762010.036
cellular response to organic cyclic compoundGO:00714071270.035
regulation of purine nucleotide metabolic processGO:19005422640.035
hydrogen peroxide metabolic processGO:0042743200.035
Human Mouse Worm
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.034
immune effector processGO:00022521590.034
Mouse
proteasomal protein catabolic processGO:00104981760.034
cellular response to oxygen containing compoundGO:19017012760.033
negative regulation of protein maturationGO:19033181420.033
Human
system processGO:00030083490.033
cellular protein catabolic processGO:00442572610.033
cell death in response to oxidative stressGO:0036473290.033
purine ribonucleoside metabolic processGO:00461284370.033
proton transportGO:0015992220.033
regulation of mitochondrial membrane potentialGO:0051881230.032
Human
superoxide metabolic processGO:0006801200.032
organic acid biosynthetic processGO:0016053970.032
regulation of cell cycle processGO:00105642660.032
mitotic cell cycle phase transitionGO:00447721620.032
regulation of neuroblast proliferationGO:190269230.031
positive regulation of cellular amine metabolic processGO:003324070.031
regulation of cellular response to oxidative stressGO:1900407260.031
purine ribonucleotide catabolic processGO:00091544040.031
biological adhesionGO:00226103310.031
cation transmembrane transportGO:00986552380.031
positive regulation of apoptotic signaling pathwayGO:2001235700.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
adult locomotory behaviorGO:000834410.030
negative regulation of apoptotic processGO:00430663160.030
Human Mouse Rat
regulation of reactive oxygen species metabolic processGO:2000377410.030
Mouse
nucleoside triphosphate catabolic processGO:00091433940.030
small molecule biosynthetic processGO:00442831570.030
positive regulation of hydrolase activityGO:00513453310.030
positive regulation of apoptotic processGO:00430652460.029
nucleotide catabolic processGO:00091664080.029
dna integrity checkpointGO:0031570710.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
alcohol metabolic processGO:00060661140.029
lipid biosynthetic processGO:00086101770.029
regulation of protein localization to nucleusGO:1900180850.028
purine nucleoside monophosphate metabolic processGO:00091261860.028
negative regulation of hydrolase activityGO:00513461820.028
Human
cellular macromolecule catabolic processGO:00442653800.028
regulation of protein catabolic processGO:00421761550.028
positive regulation of catabolic processGO:00098963100.028
regulation of cell cycle phase transitionGO:19019871260.028
regulation of protein stabilityGO:0031647870.028
response to metal ionGO:0010038840.028
Worm
steroid metabolic processGO:0008202940.028
negative regulation of multicellular organismal processGO:00512413170.028
Mouse
regulation of transporter activityGO:0032409820.027
glycosyl compound catabolic processGO:19016584130.027
nucleoside monophosphate metabolic processGO:00091231910.027
negative regulation of phosphorylationGO:00423261740.027
Human
protein catabolic processGO:00301633250.026
positive regulation of nucleotide metabolic processGO:00459812300.026
negative regulation of proteolysisGO:00458611320.026
Human
negative regulation of kinase activityGO:00336731060.026
Human
response to drugGO:0042493810.026
negative regulation of cell cycle processGO:00109481210.026
negative regulation of phosphorus metabolic processGO:00105632670.026
Human
inflammatory responseGO:0006954790.026
Mouse
regulation of locomotionGO:00400123290.026
negative regulation of transportGO:00510511760.026
positive regulation of organelle organizationGO:00106381950.025
oogenesisGO:004847720.025
negative regulation of protein phosphorylationGO:00019331400.025
protein modification by small protein removalGO:0070646920.025
nucleoside triphosphate metabolic processGO:00091414220.025
protein deubiquitinationGO:0016579790.025
mitotic cell cycleGO:00002783260.025
peptidyl serine modificationGO:00182091060.024
monovalent inorganic cation transportGO:00156721280.024
negative regulation of protein modification processGO:00314002000.024
amine metabolic processGO:0009308440.024
nuclear transportGO:00511691790.024
epithelial cell proliferationGO:00506731280.024
regulation of transmembrane transporter activityGO:0022898740.024
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.024
single organism membrane organizationGO:00448022680.024
purine nucleotide catabolic processGO:00061954050.024
protein homooligomerizationGO:00512601000.023
ribonucleoside monophosphate metabolic processGO:00091611870.023
regulation of cellular component biogenesisGO:00440872810.023
cell adhesionGO:00071553250.023
regulation of response to woundingGO:19030341010.023
Mouse
regulation of cellular ketone metabolic processGO:0010565500.023
regulation of epithelial cell proliferationGO:00506781130.023
generation of neuronsGO:00486991520.023
female gamete generationGO:000729220.022
regulation of cell differentiationGO:00455953930.022
Mouse
negative regulation of intracellular signal transductionGO:19025321830.022
negative regulation of programmed cell deathGO:00430693210.022
Human Mouse Rat
protein localization to organelleGO:00333652800.021
regulation of defense responseGO:00313471540.021
positive regulation of peptidase activityGO:0010952880.021
intracellular receptor signaling pathwayGO:00305221040.021
ribonucleoside catabolic processGO:00424544060.021
positive regulation of immune system processGO:00026842830.021
cation homeostasisGO:00550801890.021
membrane organizationGO:00610242920.020
phospholipid metabolic processGO:0006644990.020
cellular chemical homeostasisGO:00550821800.020
endomembrane system organizationGO:00102561960.020
gtp catabolic processGO:00061842370.020
positive regulation of cellular component organizationGO:00511303760.020
regulation of synaptic plasticityGO:004816730.020
purine containing compound catabolic processGO:00725234110.020
reactive oxygen species biosynthetic processGO:190340940.020
endothelial cell proliferationGO:0001935650.020
protein importGO:00170381300.020
locomotory behaviorGO:000762610.020
regulation of anatomical structure morphogenesisGO:00226032860.020
multicellular organismal homeostasisGO:0048871670.020
Human
alcohol biosynthetic processGO:0046165520.020
retina homeostasisGO:0001895420.019
Human
regenerationGO:003109940.019
organic hydroxy compound biosynthetic processGO:1901617710.019
dopamine uptake involved in synaptic transmissionGO:005158340.019
response to organic cyclic compoundGO:00140702040.019
regulation of nucleotide metabolic processGO:00061402690.019
positive regulation of cysteine type endopeptidase activityGO:2001056790.019
organelle fissionGO:00482851490.019
defense responseGO:00069523150.019
Mouse
positive regulation of response to oxidative stressGO:190288470.018
positive regulation of transportGO:00510503360.018
regulation of vitamin metabolic processGO:003065690.018
immune responseGO:00069553070.018
mitotic nuclear divisionGO:00070671190.018
positive regulation of ion transportGO:0043270870.018
purine ribonucleoside catabolic processGO:00461303980.018
nervous system developmentGO:00073992930.018
energy derivation by oxidation of organic compoundsGO:0015980430.018
negative regulation of cell proliferationGO:00082852280.018
establishment of protein localization to organelleGO:00725941720.018
metal ion transportGO:00300012720.018
modification dependent protein catabolic processGO:00199412090.018
protein dephosphorylationGO:0006470810.018
mitotic cell cycle checkpointGO:0007093680.017
interspecies interaction between organismsGO:00444191560.017
reactive nitrogen species metabolic processGO:200105730.017
negative regulation of cellular component organizationGO:00511292350.017
regulation of cell migrationGO:00303342890.017
regulation of mitotic cell cycle phase transitionGO:19019901180.017
anatomical structure homeostasisGO:00602491000.017
Human
positive regulation of phosphorylationGO:00423273940.017
Mouse
nucleoside phosphate catabolic processGO:19012924120.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.017
positive regulation of protein phosphorylationGO:00019343130.017
Mouse
negative regulation of cell cycleGO:00457861930.017
cytoplasmic transportGO:00164823790.017
monocarboxylic acid biosynthetic processGO:0072330670.016
negative regulation of cell deathGO:00605483450.016
Human Mouse Rat
positive regulation of reactive oxygen species metabolic processGO:2000379240.016
mitotic cell cycle processGO:19030472860.016
regulation of protein kinase activityGO:00458592890.016
Mouse
response to activityGO:001482300.016
negative regulation of intracellular transportGO:0032387600.016
hemopoiesisGO:00300971800.016
Mouse
negative regulation of neuron deathGO:1901215320.016
Rat
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.016
regulation of neuron apoptotic processGO:0043523350.016
Rat
regulation of small gtpase mediated signal transductionGO:00510561560.016
myeloid cell differentiationGO:00300991170.016
nadph oxidationGO:007099530.016
nitrogen compound transportGO:00717051910.016
mitochondrial transportGO:0006839600.016
spinal cord developmentGO:002151040.016
negative regulation of protein catabolic processGO:0042177590.016
regulation of protein transportGO:00512232130.016
response to oxygen levelsGO:00704821000.016
positive regulation of protein catabolic processGO:0045732750.015
circulatory system developmentGO:00723592620.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
negative regulation of cytoplasmic transportGO:1903650460.015
regulation of multi organism processGO:00439001570.015
Mouse
coenzyme metabolic processGO:0006732650.015
positive regulation of cytokine productionGO:00018191670.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
nucleotide biosynthetic processGO:00091651090.015
growthGO:00400072020.015
Worm
response to radiationGO:00093141510.015
regulation of ligase activityGO:0051340290.015
posttranscriptional regulation of gene expressionGO:00106082130.015
mitochondrial membrane organizationGO:0007006400.015
negative regulation of protein kinase activityGO:0006469980.015
regulation of nucleocytoplasmic transportGO:0046822980.015
regulation of cytoplasmic transportGO:19036491490.014
secretion by cellGO:00329402260.014
regulation of cell motilityGO:20001452990.014
cellular respirationGO:0045333210.014
negative regulation of cellular protein catabolic processGO:1903363380.014
cell agingGO:0007569520.014
embryo developmentGO:00097901230.014
regulation of growthGO:00400081650.014
Worm
mapk cascadeGO:00001652880.013
Mouse
ameboidal type cell migrationGO:00016671350.013
regulation of cell developmentGO:00602841610.013
negative regulation of stem cell proliferationGO:200064730.013
lipid modificationGO:0030258840.013
mitotic dna integrity checkpointGO:0044774300.013
nucleoside phosphate biosynthetic processGO:19012931090.013
alpha amino acid metabolic processGO:1901605720.013
angiotensin activated signaling pathwayGO:003816640.013
regulation of cytokine productionGO:00018172320.013
response to hypoxiaGO:0001666960.013
reproductionGO:0000003630.013
regulation of response to oxidative stressGO:1902882260.013
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.013
circulatory system processGO:00030131130.013
regulation of ubiquitin protein transferase activityGO:0051438280.013
positive regulation of peptidyl serine phosphorylationGO:0033138420.013
negative regulation of mitotic cell cycleGO:00459301020.013
negative regulation of neural precursor cell proliferationGO:200017810.013
regulation of transmembrane transportGO:00347621390.012
ion homeostasisGO:00508012300.012
positive regulation of proteolysisGO:00458621420.012
neuromuscular junction developmentGO:000752830.012
regulation of oxidative stress induced cell deathGO:1903201240.012
negative regulation of bindingGO:0051100570.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
sensory perception of painGO:001923340.012
positive regulation of transporter activityGO:0032411320.012
response to superoxideGO:000030360.012
negative regulation of protein transportGO:0051224750.012
nucleocytoplasmic transportGO:00069131760.012
single organism cell adhesionGO:00986021790.012
myosin filament assemblyGO:003103420.012
innate immune responseGO:00450871780.012
segmentationGO:003528240.012
response to nitrogen compoundGO:19016981840.012
agingGO:0007568660.012
Worm
myosin filament organizationGO:003103320.012
chemotaxisGO:00069351570.012
regulation of nucleoside metabolic processGO:00091182090.012
regulation of cell morphogenesisGO:00226041530.011
single organismal cell cell adhesionGO:00163371480.011
neuron death in response to oxidative stressGO:003647590.011
cellular response to oxygen levelsGO:0071453550.011
cell morphogenesisGO:00009022960.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
Human
regulation of rho protein signal transductionGO:0035023790.011
regulation of cellular component movementGO:00512703340.011
positive regulation of oxidative stress induced cell deathGO:190320950.011
nuclear divisionGO:00002801280.011
cellular protein complex assemblyGO:00436231880.011
positive regulation of cell cycleGO:00457871400.011
ribonucleotide biosynthetic processGO:0009260810.011
protein oligomerizationGO:00512591730.011
negative regulation of catabolic processGO:00098951040.011
intracellular protein transportGO:00068862700.011
regulation of nervous system developmentGO:0051960880.011
purine containing compound biosynthetic processGO:0072522880.011
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.011
positive regulation of leukocyte activationGO:0002696800.011
positive regulation of developmental processGO:00510943140.011
Worm
generation of precursor metabolites and energyGO:0006091680.011
regulation of mapk cascadeGO:00434082620.011
Mouse
regulation of bindingGO:00510981110.011
gtp metabolic processGO:00460392390.011
positive regulation of nucleoside metabolic processGO:00459791860.011
regulation of oxidative stress induced neuron deathGO:190320390.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
regulation of cholesterol metabolic processGO:009018140.011
ribonucleoside triphosphate catabolic processGO:00092033910.011
ribose phosphate biosynthetic processGO:0046390820.011
negative regulation of immune system processGO:00026831360.010
Mouse
regulation of intracellular protein transportGO:00331571230.010
response to hormoneGO:00097251750.010
actin filament based processGO:00300292240.010
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.010
catecholamine uptake involved in synaptic transmissionGO:005193440.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
Human Mouse
regulation of gtp catabolic processGO:00331241800.010
negative regulation of lipid metabolic processGO:0045833380.010
guanosine containing compound metabolic processGO:19010682440.010
carboxylic acid catabolic processGO:0046395710.010
peptidyl tyrosine phosphorylationGO:00181081700.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
protein targetingGO:00066051870.010
regulation of inflammatory responseGO:0050727460.010
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.010
guanosine containing compound catabolic processGO:19010692390.010
dendritic spine organizationGO:009706140.010
positive regulation of transmembrane transportGO:0034764410.010
blood circulationGO:00080151130.010
signal transduction by p53 class mediatorGO:0072331720.010

PRDX2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.069
disease of metabolismDOID:00146672950.069
nervous system diseaseDOID:8634310.061
central nervous system diseaseDOID:3311860.061
neurodegenerative diseaseDOID:12891020.047
sensory system diseaseDOID:00501552030.027
disease of cellular proliferationDOID:145661740.021
disease of mental healthDOID:150700.018
eye diseaseDOID:56141490.018
eye and adnexa diseaseDOID:14921500.018
retinal diseaseDOID:56791180.014
retinal degenerationDOID:8466890.014
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
carbohydrate metabolic disorderDOID:2978550.011