Homo sapiens

114 known processes

PITX2

paired-like homeodomain 2

(Aliases: IRID2,MGC111022,IGDS,RS,PTX2,RIEG,IHG2,Otlx2,RGS,RIEG1,IDG2,Brx1,MGC20144,ARP1,IGDS2)

PITX2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
extraocular skeletal muscle developmentGO:000207410.786
Mouse
circulatory system developmentGO:00723592620.326
Zebrafish Mouse
anatomical structure formation involved in morphogenesisGO:00486462840.266
Zebrafish Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.258
cardiovascular system developmentGO:00723582620.239
Zebrafish Mouse
cranial nerve developmentGO:002154540.218
organ morphogenesisGO:00098871470.212
skeletal system developmentGO:0001501790.190
epithelium developmentGO:00604292270.174
Zebrafish Mouse
regulation of cell differentiationGO:00455953930.169
nerve developmentGO:002167540.159
vasculature developmentGO:00019441810.156
Mouse
blood vessel developmentGO:00015681720.150
Mouse
negative regulation of developmental processGO:00510932470.144
tube morphogenesisGO:0035239950.143
Mouse
cellular ketone metabolic processGO:0042180800.140
negative regulation of multicellular organismal processGO:00512413170.135
hindbrain developmentGO:003090230.135
negative regulation of cell differentiationGO:00455961710.134
cellular component morphogenesisGO:00329893140.133
Worm Fly
stem cell differentiationGO:0048863930.131
Mouse
cellular response to endogenous stimulusGO:00714953360.131
neuron fate commitmentGO:004866320.131
system processGO:00030083490.127
Zebrafish
positive regulation of developmental processGO:00510943140.117
epithelial cell differentiationGO:00308551410.116
amine metabolic processGO:0009308440.110
embryonic morphogenesisGO:0048598850.110
Zebrafish Mouse
regulation of cellular ketone metabolic processGO:0010565500.110
tube developmentGO:00352951250.110
Zebrafish Mouse
cell morphogenesisGO:00009022960.109
Worm Fly
post embryonic developmentGO:000979120.109
organ formationGO:004864530.108
segmentationGO:003528240.108
regulation of cellular component movementGO:00512703340.107
Mouse
menstrual cycle phaseGO:002260120.106
regulation of anatomical structure morphogenesisGO:00226032860.104
cell developmentGO:00484683280.103
Mouse Worm Fly
stem cell developmentGO:0048864690.101
Mouse
mesenchyme developmentGO:0060485590.100
Mouse
nervous system developmentGO:00073992930.098
Zebrafish Mouse Rat Worm Fly
embryonic forelimb morphogenesisGO:003511540.098
specification of organ identityGO:001009230.096
cell fate determinationGO:000170930.096
enzyme linked receptor protein signaling pathwayGO:00071673030.095
forelimb morphogenesisGO:003513640.095
positive regulation of aldosterone metabolic processGO:003234620.093
regulation of cell cycleGO:00517263930.093
regulation of cell motilityGO:20001452990.093
Mouse
positive regulation of cell proliferationGO:00082843010.092
Mouse
response to lipidGO:00339932060.089
Rat
regulation of locomotionGO:00400123290.084
Mouse Worm
cellular amine metabolic processGO:0044106410.083
tissue morphogenesisGO:0048729960.083
Zebrafish Mouse
positive regulation of cell differentiationGO:00455972110.082
forebrain regionalizationGO:002187130.080
cardiac right ventricle morphogenesisGO:000321530.078
negative regulation of cell deathGO:00605483450.076
regulation of sequence specific dna binding transcription factor activityGO:00510902110.076
regulation of hormone levelsGO:00108171250.076
digestive tract developmentGO:0048565750.075
Zebrafish Mouse
lipid metabolic processGO:00066293810.075
muscle structure developmentGO:0061061980.075
Mouse
negative regulation of apoptotic processGO:00430663160.075
positive regulation of cell deathGO:00109422630.075
cellular amino acid metabolic processGO:00065201160.072
mesenchymal cell differentiationGO:0048762520.071
Mouse
cardiac cell fate determinationGO:006091330.070
response to oxygen containing compoundGO:19017003690.070
embryonic camera type eye developmentGO:003107620.069
Zebrafish Mouse
positive regulation of apoptotic processGO:00430652460.069
kidney developmentGO:0001822530.069
ossificationGO:00015031210.068
regulation of cellular amino acid metabolic processGO:000652160.066
heart developmentGO:0007507950.066
Zebrafish Mouse
cell morphogenesis involved in differentiationGO:00009041440.066
Worm Fly
regulation of cell developmentGO:00602841610.065
bmp signaling pathway involved in heart developmentGO:006131230.065
negative regulation of cellular component organizationGO:00511292350.065
positive regulation of cellular amino acid metabolic processGO:004576430.064
positive regulation of programmed cell deathGO:00430682490.063
regulation of cell migrationGO:00303342890.060
Mouse
positive regulation of aldosterone biosynthetic processGO:003234920.060
positive regulation of transportGO:00510503360.059
negative regulation of cell proliferationGO:00082852280.059
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.058
regulation of cellular amine metabolic processGO:0033238110.057
somatic stem cell maintenanceGO:003501940.057
regionalizationGO:0003002290.057
Zebrafish Mouse
negative regulation of kidney developmentGO:009018520.057
positive regulation of cellular amine metabolic processGO:003324070.057
mitotic cell cycleGO:00002783260.057
urogenital system developmentGO:0001655650.057
locomotory behaviorGO:000762610.056
positive regulation of hormone biosynthetic processGO:004688640.055
immune system developmentGO:00025201950.055
Mouse
neural crest cell developmentGO:001403230.054
Mouse
pancreas developmentGO:0031016190.054
pattern specification processGO:0007389430.054
Zebrafish Mouse
mesenchymal cell developmentGO:0014031500.053
Mouse
negative regulation of programmed cell deathGO:00430693210.053
regulation of ossificationGO:0030278580.053
inner ear morphogenesisGO:004247240.053
single organism cellular localizationGO:19025803320.053
blood vessel morphogenesisGO:00485141620.052
Mouse
heart morphogenesisGO:0003007480.051
Mouse
negative regulation of protein metabolic processGO:00512483910.050
cytoplasmic transportGO:00164823790.050
digestive system developmentGO:0055123750.050
Zebrafish Mouse
neurogenesisGO:00220081690.050
Mouse Rat Worm Fly
neuron differentiationGO:00301821380.050
Rat Worm Fly
protein localization to organelleGO:00333652800.049
heart formationGO:006091420.049
striated muscle tissue developmentGO:0014706590.048
Mouse
generation of neuronsGO:00486991520.048
Mouse Rat Worm Fly
morphogenesis of embryonic epitheliumGO:001633140.048
Zebrafish
regulation of mitotic cell cycleGO:00073461890.048
cellular response to oxygen containing compoundGO:19017012760.048
negative regulation of locomotionGO:00400131180.048
regulation of stem cell differentiationGO:2000736560.048
negative regulation of cellular protein metabolic processGO:00322693530.048
mesendoderm developmentGO:004838210.047
Zebrafish
biological adhesionGO:00226103310.047
negative regulation of cell cycleGO:00457861930.047
somitogenesisGO:000175620.047
signal transduction by phosphorylationGO:00230142970.047
regulation of protein transportGO:00512232130.046
brain developmentGO:0007420970.046
Mouse Rat
endocrine system developmentGO:0035270260.046
Mouse
response to organic cyclic compoundGO:00140702040.046
secretionGO:00469032540.046
secretion by cellGO:00329402260.046
positive regulation of phosphorylationGO:00423273940.046
response to abiotic stimulusGO:00096283360.045
testosterone biosynthetic processGO:006137020.045
positive regulation of steroid hormone biosynthetic processGO:009003120.045
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.045
peripheral nervous system developmentGO:000742220.044
regulation of endopeptidase activityGO:00525481700.044
forebrain generation of neuronsGO:002187230.043
regulation of protein localizationGO:00328802960.043
regulation of proteolysisGO:00301622930.043
nitrogen compound transportGO:00717051910.043
renal system developmentGO:0072001630.043
hematopoietic or lymphoid organ developmentGO:00485341860.043
Mouse
motor neuron axon guidanceGO:000804520.042
cellular lipid metabolic processGO:00442553030.042
mapk cascadeGO:00001652880.042
embryonic organ developmentGO:0048568360.042
Zebrafish Mouse
osteoblast differentiationGO:0001649920.042
positive regulation of protein phosphorylationGO:00019343130.042
regulation of peptidase activityGO:00525471800.042
taxisGO:00423301570.042
Worm
muscle tissue developmentGO:0060537620.042
Mouse
pharynx developmentGO:006046510.042
regulation of secretion by cellGO:19035301770.042
negative regulation of phosphate metabolic processGO:00459362670.041
metencephalon developmentGO:002203720.041
embryonic epithelial tube formationGO:000183840.041
soft palate developmentGO:006002330.041
hormone secretionGO:0046879650.041
central nervous system developmentGO:00074171230.041
Mouse Rat
regulation of heart induction by regulation of canonical wnt signaling pathwayGO:009008110.041
cell projection organizationGO:00300302520.040
Worm Fly
negative regulation of phosphorus metabolic processGO:00105632670.040
regulation of establishment of protein localizationGO:00702012420.040
cell cell signalingGO:00072671550.040
negative regulation of cell migrationGO:00303361020.040
embryo developmentGO:00097901230.039
Zebrafish Mouse
pituitary gland developmentGO:002198320.039
Mouse
regulation of cellular component biogenesisGO:00440872810.039
response to hormoneGO:00097251750.039
Rat
head developmentGO:00603221080.039
Zebrafish Mouse Rat
regulation of secretionGO:00510461940.039
anterior posterior axis specificationGO:000994820.039
female gamete generationGO:000729220.039
cell adhesionGO:00071553250.038
regulation of kinase activityGO:00435493140.038
regulation of cell morphogenesisGO:00226041530.038
blood circulationGO:00080151130.038
Zebrafish
actin filament based processGO:00300292240.038
regulation of cell cycle processGO:00105642660.038
determination of adult lifespanGO:000834020.038
negative regulation of cellular component movementGO:00512711060.038
regulation of transferase activityGO:00513383550.037
regulation of mapk cascadeGO:00434082620.037
multicellular organismal agingGO:001025930.037
negative regulation of catalytic activityGO:00430863350.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.037
regulation of cytokine productionGO:00018172320.037
intracellular protein transportGO:00068862700.037
epithelial to mesenchymal transitionGO:0001837480.036
spinal cord developmentGO:002151040.036
blastoderm segmentationGO:000735020.036
lipid biosynthetic processGO:00086101770.036
wnt signaling pathwayGO:00160551560.036
Mouse
connective tissue developmentGO:0061448390.036
small molecule biosynthetic processGO:00442831570.036
positive regulation of organelle organizationGO:00106381950.035
cytokine productionGO:00018162470.035
growthGO:00400072020.035
chordate embryonic developmentGO:0043009340.035
Zebrafish Mouse
skeletal system morphogenesisGO:0048705240.035
Zebrafish
cellular response to dna damage stimulusGO:00069743790.035
positive regulation of protein transportGO:00512221350.035
chromatin organizationGO:00063253510.034
muscle organ developmentGO:0007517560.034
Mouse
positive regulation of cell developmentGO:0010720920.034
oogenesisGO:004847720.034
cellular response to hormone stimulusGO:00328701250.034
response to growth factorGO:00708482050.034
apoptotic signaling pathwayGO:00971902680.034
hard palate developmentGO:006002210.034
oxidation reduction processGO:00551143960.034
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.033
positive regulation of cellular component organizationGO:00511303760.033
immune responseGO:00069553070.033
endodermal cell fate commitmentGO:000171140.033
menstruationGO:004270310.033
hindlimb morphogenesisGO:003513720.033
Mouse
cellular response to lipidGO:00713961270.033
limbic system developmentGO:002176130.032
Mouse
photoreceptor cell differentiationGO:004653020.032
positive regulation of hydrolase activityGO:00513453310.032
regulation of protein kinase activityGO:00458592890.032
chromatin modificationGO:00165682980.032
epithelial cell proliferationGO:00506731280.032
positive regulation of tooth mineralizationGO:007017220.032
cellular macromolecule catabolic processGO:00442653800.031
canonical wnt signaling pathwayGO:00600701160.031
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.030
aortic valve developmentGO:000317630.030
negative regulation of protein modification processGO:00314002000.030
outflow tract septum morphogenesisGO:000314840.030
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.030
negative regulation of glomerulus developmentGO:009019420.030
nucleocytoplasmic transportGO:00069131760.030
thymus developmentGO:004853830.030
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.030
regulation of heart morphogenesisGO:200082640.030
adult locomotory behaviorGO:000834410.030
regulation of cysteine type endopeptidase activityGO:20001161270.030
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.029
muscle contractionGO:0006936730.029
detection of chemical stimulus involved in sensory perception of smellGO:005091120.029
positive regulation of peptidase activityGO:0010952880.029
intracellular receptor signaling pathwayGO:00305221040.029
Zebrafish
epithelial tube branching involved in lung morphogenesisGO:006044140.029
regulation of epithelial to mesenchymal transitionGO:0010717370.029
reproductive processGO:00224141060.029
Rat
cell divisionGO:00513011680.029
negative regulation of cell motilityGO:20001461040.029
mesonephros developmentGO:0001823170.029
regulation of growthGO:00400081650.029
cellular response to growth factor stimulusGO:00713631970.029
regulation of organ formationGO:000315640.028
regulation of cellular response to stressGO:00801352440.028
regulation of intracellular transportGO:00323861950.028
positive regulation of proteolysisGO:00458621420.028
gland developmentGO:0048732480.028
Mouse
posttranscriptional regulation of gene expressionGO:00106082130.028
protein localization to nucleusGO:00345041360.028
positive regulation of immune system processGO:00026842830.028
response to biotic stimulusGO:00096072760.028
positive regulation of glucocorticoid biosynthetic processGO:003194810.028
nuclear transportGO:00511691790.028
negative regulation of phosphorylationGO:00423261740.028
bmp signaling pathwayGO:0030509490.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.027
cell projection morphogenesisGO:00488581290.027
Worm Fly
cell growthGO:00160491600.027
neurological system processGO:00508771630.027
response to woundingGO:00096111680.027
positive regulation of cardioblast differentiationGO:005189120.027
neuron projection developmentGO:00311751060.027
Worm Fly
positive regulation of mapk cascadeGO:00434101900.027
developmental programmed cell deathGO:001062330.027
hemopoiesisGO:00300971800.027
sensory organ developmentGO:0007423520.027
retinal ganglion cell axon guidanceGO:003129020.027
negative regulation of vasculature developmentGO:1901343430.027
negative regulation of transportGO:00510511760.026
regenerationGO:003109940.026
covalent chromatin modificationGO:00165692540.026
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.026
hair follicle morphogenesisGO:003106920.026
defense responseGO:00069523150.026
response to steroid hormoneGO:0048545800.026
hormone metabolic processGO:0042445610.026
regulation of cell morphogenesis involved in differentiationGO:0010769830.026
negative regulation of cell growthGO:0030308830.026
monocarboxylic acid metabolic processGO:00327871850.026
protein targetingGO:00066051870.026
forebrain neuron differentiationGO:002187930.026
endodermal cell fate specificationGO:000171440.026
cranial nerve morphogenesisGO:002160210.026
regulation of lipid metabolic processGO:0019216960.026
muscle system processGO:0003012810.025
positive regulation of cytokine productionGO:00018191670.025
sex determinationGO:000753030.025
regulation of cytoplasmic transportGO:19036491490.025
negative regulation of protein phosphorylationGO:00019331400.025
organic hydroxy compound metabolic processGO:19016151470.025
dermatome developmentGO:006105430.025
positive regulation of cell cycleGO:00457871400.025
establishment of protein localization to organelleGO:00725941720.025
negative regulation of intracellular signal transductionGO:19025321830.025
cerebellum developmentGO:002154920.025
negative regulation of mitotic cell cycleGO:00459301020.025
positive regulation of cellular component movementGO:00512721810.025
positive regulation of cysteine type endopeptidase activityGO:2001056790.025
mitotic cell cycle processGO:19030472860.025
positive regulation of cell motilityGO:20001471770.025
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.025
positive regulation of secretion by cellGO:19035321080.025
mesodermal cell fate commitmentGO:000171020.025
regulation of homeostatic processGO:00328441210.025
neuromuscular junction developmentGO:000752830.024
positive regulation of ossificationGO:0045778320.024
regulation of wnt signaling pathwayGO:00301111230.024
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.024
regulation of response to external stimulusGO:00321012220.024
cellular response to organic cyclic compoundGO:00714071270.024
positive regulation of cellular component biogenesisGO:00440891580.024
negative regulation of cell proliferation involved in kidney developmentGO:190172320.024
vesicle mediated transportGO:00161923710.024
endocrine pancreas developmentGO:0031018110.024
regulation of cell growthGO:00015581350.024
regulation of protein serine threonine kinase activityGO:00719001790.024
neuron developmentGO:00486661130.024
Worm Fly
regulation of branching involved in ureteric bud morphogenesisGO:009018930.024
alcohol metabolic processGO:00060661140.024
steroid metabolic processGO:0008202940.023
cardiac ventricle formationGO:000321120.023
regulation of cell proliferation involved in kidney developmentGO:190172230.023
compound eye developmentGO:004874910.023
positive regulation of cellular catabolic processGO:00313312840.023
neural tube formationGO:000184130.023
embryonic camera type eye formationGO:006090020.023
Zebrafish
regulation of apoptotic signaling pathwayGO:20012331750.023
androgen biosynthetic processGO:000670230.023
cell differentiation in spinal cordGO:002151510.023
signal releaseGO:0023061700.023
protein importGO:00170381300.023
single organism reproductive processGO:0044702980.023
Rat
embryonic skeletal system developmentGO:0048706130.023
Zebrafish
positive regulation of odontogenesisGO:004248230.023
regulation of osteoblast differentiationGO:0045667380.023
cardiac muscle contractionGO:0060048340.023
regulation of canonical wnt signaling pathwayGO:0060828880.022
positive regulation of secretionGO:00510471160.022
single organism carbohydrate metabolic processGO:00447231930.022
response to other organismGO:00517072610.022
small gtpase mediated signal transductionGO:0007264780.022
positive regulation of osteoblast differentiationGO:0045669230.022
positive regulation of epithelial cell proliferationGO:0050679650.022
negative regulation of gliogenesisGO:001401430.022
chemotaxisGO:00069351570.022
Worm
hormone transportGO:0009914680.022
regulation of nervous system developmentGO:0051960880.022
regulation of intracellular protein transportGO:00331571230.022
intracellular steroid hormone receptor signaling pathwayGO:0030518610.022
cell part morphogenesisGO:00329901370.022
Worm Fly
ras protein signal transductionGO:0007265730.022
peptide transportGO:0015833740.022
response to fungusGO:000962040.022
transmembrane transportGO:00550853990.022
memoryGO:000761330.022
embryonic camera type eye morphogenesisGO:004859620.022
Zebrafish
circulatory system processGO:00030131130.022
Zebrafish
tongue developmentGO:004358610.022
single organism membrane organizationGO:00448022680.022
histone modificationGO:00165702510.022
cardiac muscle cell contractionGO:008600340.022
matingGO:000761810.021
regulation of cell adhesionGO:00301551660.021
purine containing compound catabolic processGO:00725234110.021
regulation of epithelial cell proliferationGO:00506781130.021
positive regulation of neural precursor cell proliferationGO:200017920.021
single organism nuclear importGO:19025931040.021
organophosphate catabolic processGO:00464344300.021
type b pancreatic cell developmentGO:000332340.021
visual behaviorGO:000763220.021
cell proliferation in forebrainGO:002184610.021
trophectodermal cell differentiationGO:000182930.021
response to external biotic stimulusGO:00432072610.021
membrane organizationGO:00610242920.021
myeloid cell differentiationGO:00300991170.021
regulation of testosterone biosynthetic processGO:200022420.021
regulation of dna metabolic processGO:00510521530.021
embryonic hindlimb morphogenesisGO:003511620.021
Mouse
positive regulation of stem cell differentiationGO:2000738290.021
positive regulation of endopeptidase activityGO:0010950840.021
amide transportGO:0042886760.021
heart field specificationGO:000312820.021
cardiac muscle tissue developmentGO:0048738390.021
Mouse
regulation of multi organism processGO:00439001570.021
negative regulation of organelle organizationGO:00106391260.021
organonitrogen compound biosynthetic processGO:19015662000.021
organelle assemblyGO:00709251760.021
nuclear importGO:00511701060.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.021
morphogenesis of an epitheliumGO:0002009600.021
Zebrafish Mouse
positive regulation of catabolic processGO:00098963100.021
positive regulation of dermatome developmentGO:006118430.021
odontogenesisGO:0042476250.021
cartilage developmentGO:0051216310.021
angiogenesisGO:00015251470.021
Mouse
forebrain dorsal ventral pattern formationGO:002179810.021
positive regulation of locomotionGO:00400171860.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
limb bud formationGO:006017410.021
negative regulation of growthGO:0045926970.021
non canonical wnt signaling pathway via mapk cascadeGO:003803040.020
tissue migrationGO:00901301190.020
regulation of cell divisionGO:00513021160.020
negative regulation of glucocorticoid biosynthetic processGO:003194740.020
striated muscle contractionGO:0006941520.020
nucleoside triphosphate metabolic processGO:00091414220.020
regulation of vasculature developmentGO:1901342970.020
salivary gland morphogenesisGO:000743540.020
blastocyst developmentGO:000182430.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
peptide secretionGO:0002790510.020
regulation of neurogenesisGO:0050767820.020
glycosyl compound catabolic processGO:19016584130.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
optic nerve developmentGO:002155420.020
wound healingGO:00420601150.020
cellular macromolecular complex assemblyGO:00346223240.020
epidermis morphogenesisGO:004873030.020
regulation of neural precursor cell proliferationGO:200017740.020
protein targeting to nucleusGO:00447441040.020
protein ubiquitinationGO:00165673140.020
anterior posterior axis specification embryoGO:000859520.020
ribonucleoside catabolic processGO:00424544060.020
ameboidal type cell migrationGO:00016671350.020
Mouse
blastocyst formationGO:000182530.020
negative regulation of monocyte differentiationGO:004565630.020
pulmonary vein morphogenesisGO:006057710.020
Mouse
cartilage condensationGO:000150210.020
epidermis developmentGO:0008544590.020
formation of primary germ layerGO:0001704420.020
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433620.020
epidermal cell differentiationGO:0009913450.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
syncytium formation by plasma membrane fusionGO:000076820.020
Mouse
actin cytoskeleton organizationGO:00300362070.020
positive regulation of transferase activityGO:00513472270.019
male genitalia developmentGO:003053910.019
positive regulation of mesenchymal cell proliferationGO:000205320.019
epithelial cell migrationGO:00106311190.019
digestive tract morphogenesisGO:0048546560.019
Mouse
tripartite regional subdivisionGO:000735120.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
cation transportGO:00068123310.019
blood coagulationGO:0007596760.019
chemical homeostasisGO:00488783060.019
purine nucleoside catabolic processGO:00061523980.019
carbohydrate metabolic processGO:00059752070.019
mesodermal cell fate specificationGO:000750120.019
startle responseGO:000196430.019
rhythmic behaviorGO:000762220.019
negative regulation of cell developmentGO:0010721480.019
negative regulation of transferase activityGO:00513481240.019
morphogenesis of a polarized epitheliumGO:000173830.019
protein catabolic processGO:00301633250.019
carbohydrate derivative biosynthetic processGO:19011372070.019
negative regulation of cellular amine metabolic processGO:003323930.019
myoblast fusionGO:000752010.019
Mouse
negative regulation of androgen biosynthetic processGO:200018010.019
negative regulation of epidermal cell differentiationGO:004560540.019
luteinizing hormone secretionGO:003227510.019
primary neural tube formationGO:001402030.019
leukocyte differentiationGO:0002521980.019

PITX2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.072
Human
sensory system diseaseDOID:00501552030.051
Human
nervous system diseaseDOID:8634310.051
Human
eye and adnexa diseaseDOID:14921500.043
Human
eye diseaseDOID:56141490.043
Human
disease of metabolismDOID:00146672950.040
muscular diseaseDOID:00800001140.029
muscle tissue diseaseDOID:661130.029
bone diseaseDOID:0080001880.028
Human
connective tissue diseaseDOID:651090.028
Human
retinal diseaseDOID:56791180.027
inherited metabolic disorderDOID:6552420.025
disease of cellular proliferationDOID:145661740.024
myopathyDOID:4231040.024
cancerDOID:1621670.024
organ system cancerDOID:00506861640.022
cardiovascular system diseaseDOID:12871060.021