Homo sapiens

0 known processes

PLEKHG2

pleckstrin homology domain containing, family G (with RhoGef domain) member 2

(Aliases: FLJ00018,FLJ38638,DKFZp667J2325,CLG,FLJ22458,ARHGEF42)

PLEKHG2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine ribonucleotide catabolic processGO:00091544040.105
Fly
organophosphate catabolic processGO:00464344300.100
Fly
glycosyl compound catabolic processGO:19016584130.099
Fly
nucleoside catabolic processGO:00091644080.093
Fly
nucleoside phosphate catabolic processGO:19012924120.083
Fly
nucleoside triphosphate metabolic processGO:00091414220.081
Fly
purine nucleoside triphosphate catabolic processGO:00091463920.081
Fly
purine nucleotide catabolic processGO:00061954050.079
Fly
purine ribonucleoside triphosphate catabolic processGO:00092073910.078
Fly
purine ribonucleoside catabolic processGO:00461303980.076
Fly
nucleoside triphosphate catabolic processGO:00091433940.073
Fly
ribonucleoside triphosphate catabolic processGO:00092033910.073
Fly
nucleotide catabolic processGO:00091664080.073
Fly
purine containing compound catabolic processGO:00725234110.073
Fly
post embryonic developmentGO:000979120.068
Fly
ribonucleoside triphosphate metabolic processGO:00091994120.068
Fly
gtp catabolic processGO:00061842370.067
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.066
Fly
regulation of cellular amino acid metabolic processGO:000652160.059
purine nucleoside triphosphate metabolic processGO:00091444120.058
Fly
ribonucleotide catabolic processGO:00092614050.057
Fly
purine nucleoside catabolic processGO:00061523980.056
Fly
ribonucleoside catabolic processGO:00424544060.056
Fly
cellular amine metabolic processGO:0044106410.053
small gtpase mediated signal transductionGO:0007264780.053
Fly
amine metabolic processGO:0009308440.052
gtp metabolic processGO:00460392390.052
Fly
guanosine containing compound metabolic processGO:19010682440.050
Fly
actin filament based processGO:00300292240.050
Worm
purine ribonucleoside metabolic processGO:00461284370.049
Fly
ras protein signal transductionGO:0007265730.049
Fly
regulation of nucleotide metabolic processGO:00061402690.049
Fly
regulation of purine nucleotide metabolic processGO:19005422640.046
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.044
cellular ketone metabolic processGO:0042180800.044
cellular amino acid metabolic processGO:00065201160.043
regulation of nucleoside metabolic processGO:00091182090.042
Fly
female gamete generationGO:000729220.041
multicellular organismal agingGO:001025930.040
regulation of cellular amine metabolic processGO:0033238110.040
guanosine containing compound catabolic processGO:19010692390.039
Fly
positive regulation of cellular component organizationGO:00511303760.039
cellular component morphogenesisGO:00329893140.038
Worm
determination of adult lifespanGO:000834020.038
oogenesisGO:004847720.038
biological adhesionGO:00226103310.037
positive regulation of cellular catabolic processGO:00313312840.037
Fly
regulation of anatomical structure morphogenesisGO:00226032860.036
positive regulation of hydrolase activityGO:00513453310.036
Fly
cell morphogenesisGO:00009022960.035
regulation of gtpase activityGO:00430871800.035
Fly
positive regulation of cellular amine metabolic processGO:003324070.035
nervous system developmentGO:00073992930.034
neuromuscular junction developmentGO:000752830.033
regulation of cellular ketone metabolic processGO:0010565500.033
regulation of cell migrationGO:00303342890.032
regulation of purine nucleotide catabolic processGO:00331212050.032
Fly
segmentationGO:003528240.032
cell adhesionGO:00071553250.031
regulation of locomotionGO:00400123290.031
negative regulation of cellular protein metabolic processGO:00322693530.031
regulation of cell differentiationGO:00455953930.031
cell projection organizationGO:00300302520.029
regulation of gtp catabolic processGO:00331241800.029
Fly
immune responseGO:00069553070.029
positive regulation of catabolic processGO:00098963100.029
Fly
positive regulation of nucleotide metabolic processGO:00459812300.029
Fly
positive regulation of purine nucleotide metabolic processGO:19005442270.028
Fly
negative regulation of protein metabolic processGO:00512483910.028
rho protein signal transductionGO:0007266260.028
Fly
response to abiotic stimulusGO:00096283360.028
negative regulation of catalytic activityGO:00430863350.028
single organism cellular localizationGO:19025803320.028
vesicle mediated transportGO:00161923710.027
Worm
positive regulation of purine nucleotide catabolic processGO:00331231850.027
Fly
positive regulation of nucleoside metabolic processGO:00459791860.027
Fly
cellular macromolecular complex assemblyGO:00346223240.027
Worm
regulation of protein localizationGO:00328802960.027
positive regulation of gtpase activityGO:00435471660.026
Fly
positive regulation of gtp catabolic processGO:00331261660.026
Fly
regulation of cellular component biogenesisGO:00440872810.026
locomotory behaviorGO:000762610.026
regulation of cellular component movementGO:00512703340.025
actin cytoskeleton organizationGO:00300362070.025
Worm
intracellular protein transportGO:00068862700.025
endomembrane system organizationGO:00102561960.025
mitotic cell cycleGO:00002783260.025
positive regulation of phosphorylationGO:00423273940.025
blastoderm segmentationGO:000735020.024
positive regulation of developmental processGO:00510943140.024
positive regulation of transportGO:00510503360.024
transmembrane transportGO:00550853990.024
negative regulation of multicellular organismal processGO:00512413170.024
cellular macromolecule catabolic processGO:00442653800.024
regenerationGO:003109940.024
signal transduction by phosphorylationGO:00230142970.023
anterior posterior axis specificationGO:000994820.023
cytoplasmic transportGO:00164823790.023
morphogenesis of embryonic epitheliumGO:001633140.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
Worm
g protein coupled receptor signaling pathwayGO:00071862070.023
chromatin organizationGO:00063253510.023
regulation of ras gtpase activityGO:00323181280.023
Fly
negative regulation of phosphorus metabolic processGO:00105632670.023
protein localization to organelleGO:00333652800.023
membrane organizationGO:00610242920.023
Worm
cell developmentGO:00484683280.023
Worm
histone modificationGO:00165702510.023
positive regulation of protein phosphorylationGO:00019343130.022
protein processingGO:00164852260.022
epithelium developmentGO:00604292270.022
regulation of kinase activityGO:00435493140.022
regulation of nucleotide catabolic processGO:00308112050.022
Fly
positive regulation of nucleotide catabolic processGO:00308131850.022
Fly
regulation of proteolysisGO:00301622930.022
regulation of cellular response to stressGO:00801352440.021
single organism membrane organizationGO:00448022680.021
single organism cell adhesionGO:00986021790.021
posttranscriptional regulation of gene expressionGO:00106082130.021
neuroblast proliferationGO:000740540.021
protein maturationGO:00516042330.021
regulation of cell cycleGO:00517263930.021
cellular response to dna damage stimulusGO:00069743790.021
enzyme linked receptor protein signaling pathwayGO:00071673030.021
mitotic cell cycle processGO:19030472860.021
chromatin modificationGO:00165682980.021
regulation of cell motilityGO:20001452990.021
negative regulation of phosphate metabolic processGO:00459362670.021
protein catabolic processGO:00301633250.021
Worm
response to oxygen containing compoundGO:19017003690.020
oocyte differentiationGO:000999420.020
ion transmembrane transportGO:00342203380.020
covalent chromatin modificationGO:00165692540.020
memoryGO:000761330.020
negative regulation of cell deathGO:00605483450.020
regulation of response to external stimulusGO:00321012220.020
actin filament organizationGO:00070151280.020
positive regulation of immune system processGO:00026842830.020
nucleoside monophosphate metabolic processGO:00091231910.020
neurological system processGO:00508771630.020
regulation of protein kinase activityGO:00458592890.019
negative regulation of developmental processGO:00510932470.019
cellular response to endogenous stimulusGO:00714953360.019
oocyte developmentGO:004859910.019
metal ion transportGO:00300012720.019
peripheral nervous system developmentGO:000742220.019
dephosphorylationGO:00163112090.019
protein targetingGO:00066051870.019
organonitrogen compound biosynthetic processGO:19015662000.019
maintenance of locationGO:00512351120.019
circulatory system developmentGO:00723592620.019
cell fate determinationGO:000170930.019
adult locomotory behaviorGO:000834410.019
growthGO:00400072020.019
regulation of transferase activityGO:00513383550.019
regulation of protein transportGO:00512232130.019
system processGO:00030083490.019
positive regulation of cell proliferationGO:00082843010.019
defense responseGO:00069523150.019
negative regulation of cellular component organizationGO:00511292350.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
microtubule based processGO:00070172100.018
negative regulation of hydrolase activityGO:00513461820.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
positive regulation of apoptotic processGO:00430652460.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
cation transportGO:00068123310.018
positive regulation of cell deathGO:00109422630.018
regulation of intracellular transportGO:00323861950.018
ion homeostasisGO:00508012300.018
regulation of cell adhesionGO:00301551660.018
negative regulation of programmed cell deathGO:00430693210.018
organelle assemblyGO:00709251760.018
Worm
hindbrain developmentGO:003090230.018
neurogenesisGO:00220081690.018
nerve developmentGO:002167540.018
negative regulation of protein modification processGO:00314002000.018
anterior posterior axis specification embryoGO:000859520.018
regulation of cell cycle processGO:00105642660.018
chemical homeostasisGO:00488783060.018
cell part morphogenesisGO:00329901370.018
regulation of cell growthGO:00015581350.018
negative regulation of apoptotic processGO:00430663160.018
regulation of establishment of protein localizationGO:00702012420.018
regulation of mapk cascadeGO:00434082620.018
cellular lipid metabolic processGO:00442553030.017
compound eye developmentGO:004874910.017
positive regulation of locomotionGO:00400171860.017
apoptotic signaling pathwayGO:00971902680.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
taxisGO:00423301570.017
positive regulation of organelle organizationGO:00106381950.017
cell activationGO:00017752130.017
lipid metabolic processGO:00066293810.017
spermatid differentiationGO:004851540.017
regulation of cell morphogenesisGO:00226041530.017
cation homeostasisGO:00550801890.017
negative regulation of cell proliferationGO:00082852280.017
motor neuron axon guidanceGO:000804520.017
generation of neuronsGO:00486991520.017
cell morphogenesis involved in differentiationGO:00009041440.016
regulation of growthGO:00400081650.016
cell growthGO:00160491600.016
peptidyl tyrosine modificationGO:00182121700.016
mapk cascadeGO:00001652880.016
negative regulation of intracellular signal transductionGO:19025321830.016
immune system developmentGO:00025201950.016
negative regulation of cellular amine metabolic processGO:003323930.016
cellular protein catabolic processGO:00442572610.016
inorganic ion transmembrane transportGO:00986602310.016
cellular cation homeostasisGO:00300031630.016
carbohydrate derivative biosynthetic processGO:19011372070.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
cardiovascular system developmentGO:00723582620.016
positive regulation of cell differentiationGO:00455972110.016
cellular response to oxygen containing compoundGO:19017012760.016
negative regulation of transportGO:00510511760.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
response to growth factorGO:00708482050.016
positive regulation of transferase activityGO:00513472270.016
protein modification by small protein conjugationGO:00324463420.016
cellular homeostasisGO:00197251960.016
regulation of ras protein signal transductionGO:00465781550.016
Fly
regulation of endopeptidase activityGO:00525481700.015
protein ubiquitinationGO:00165673140.015
regulation of cell developmentGO:00602841610.015
embryonic epithelial tube formationGO:000183840.015
cell substrate adhesionGO:00315891320.015
inorganic cation transmembrane transportGO:00986621940.015
regulation of peptidase activityGO:00525471800.015
regulation of cytoskeleton organizationGO:00514931770.015
protein localization to membraneGO:00726571600.015
positive regulation of programmed cell deathGO:00430682490.015
i kappab kinase nf kappab signalingGO:00072491660.015
tripartite regional subdivisionGO:000735120.015
spermatid developmentGO:000728640.015
innate immune responseGO:00450871780.015
neurotransmitter secretionGO:000726940.015
atp metabolic processGO:00460341760.015
positive regulation of cellular component movementGO:00512721810.015
somatic stem cell divisionGO:004810310.015
cell projection morphogenesisGO:00488581290.015
hemopoiesisGO:00300971800.015
microtubule cytoskeleton organizationGO:00002261760.015
myoblast fusionGO:000752010.015
modification dependent macromolecule catabolic processGO:00436322120.015
positive regulation of cell migrationGO:00303351720.015
positive regulation of mapk cascadeGO:00434101900.014
rna processingGO:00063962550.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
Fly
regulation of neural precursor cell proliferationGO:200017740.014
response to woundingGO:00096111680.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
salivary gland morphogenesisGO:000743540.014
cellular protein complex assemblyGO:00436231880.014
Worm
divalent metal ion transportGO:00708381520.014
regulation of immune responseGO:00507762010.014
divalent inorganic cation homeostasisGO:00725071360.014
response to biotic stimulusGO:00096072760.014
cellular ion homeostasisGO:00068731680.014
single organism carbohydrate metabolic processGO:00447231930.014
regulation of synaptic plasticityGO:004816730.014
syncytium formation by plasma membrane fusionGO:000076820.014
chemotaxisGO:00069351570.014
atp catabolic processGO:00062001570.014
neuron differentiationGO:00301821380.014
dna repairGO:00062811980.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
regulation of dna metabolic processGO:00510521530.014
response to other organismGO:00517072610.014
metal ion homeostasisGO:00550651690.014
anion transportGO:00068201610.014
response to external biotic stimulusGO:00432072610.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
cellular response to growth factor stimulusGO:00713631970.014
positive regulation of immune responseGO:00507781590.014
regulation of mitotic cell cycleGO:00073461890.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
regulation of protein catabolic processGO:00421761550.013
calcium ion homeostasisGO:00550741220.013
organ formationGO:004864530.013
peptidyl tyrosine phosphorylationGO:00181081700.013
nitrogen compound transportGO:00717051910.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
carbohydrate metabolic processGO:00059752070.013
oxidation reduction processGO:00551143960.013
positive regulation of synaptic transmissionGO:005080640.013
regulation of actin filament based processGO:00329701410.013
nuclear migrationGO:000709710.013
cell divisionGO:00513011680.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
neural tube formationGO:000184130.013
morphogenesis of a polarized epitheliumGO:000173830.013
cell cycle phase transitionGO:00447701730.013
neuron developmentGO:00486661130.013
negative regulation of protein maturationGO:19033181420.013
positive regulation of cellular component biogenesisGO:00440891580.013
negative regulation of cell differentiationGO:00455961710.013
response to oxidative stressGO:00069791210.013
endocytosisGO:00068971590.013
Worm
ossificationGO:00015031210.013
response to axon injuryGO:004867810.013
positive regulation of kinase activityGO:00336742040.013
negative regulation of immune system processGO:00026831360.013
actin mediated cell contractionGO:0070252120.013
stem cell divisionGO:001714520.013
mrna metabolic processGO:00160711750.013
endosomal transportGO:00161971290.013
positive regulation of protein kinase activityGO:00458601900.013
establishment of protein localization to membraneGO:00901501210.013
regulation of protein maturationGO:19033171500.013
negative regulation of cell cycleGO:00457861930.013
rna interferenceGO:001624640.013
cellular metal ion homeostasisGO:00068751460.013
regulation of cytokine productionGO:00018172320.013
organophosphate biosynthetic processGO:00904071630.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
spinal cord developmentGO:002151040.013
positive regulation of protein transportGO:00512221350.013
regulation of multi organism processGO:00439001570.013
regulation of meiotic cell cycleGO:005144540.013
secretion by cellGO:00329402260.013
response to cytokineGO:00340972320.012
ubiquitin dependent protein catabolic processGO:00065112060.012
negative regulation of cell growthGO:0030308830.012
regulation of ion transportGO:00432691890.012
negative regulation of proteolysisGO:00458611320.012
positive regulation of ras gtpase activityGO:00323201170.012
Fly
epithelial cell migrationGO:00106311190.012
sex determinationGO:000753030.012
cellular chemical homeostasisGO:00550821800.012
glycoprotein metabolic processGO:00091001100.012
cytokine productionGO:00018162470.012
neuron projection developmentGO:00311751060.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
rhythmic behaviorGO:000762220.012
nuclear transportGO:00511691790.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
regulation of membrane potentialGO:0042391950.012
regulation of protein processingGO:00706131500.012
cation transmembrane transportGO:00986552380.012
central nervous system developmentGO:00074171230.012
limbic system developmentGO:002176130.012
regulation of secretionGO:00510461940.012
secretionGO:00469032540.012
actin filament based movementGO:0030048170.012
leukocyte activationGO:00453211640.012
mitotic cell cycle phase transitionGO:00447721620.012
protein localization to nucleusGO:00345041360.012
cell type specific apoptotic processGO:00972851250.012
negative regulation of growthGO:0045926970.012
response to fungusGO:000962040.012
cell projection assemblyGO:00300311260.012
regulation of protein complex assemblyGO:00432541470.012
tube closureGO:006060630.012
negative regulation of phosphorylationGO:00423261740.012
photoreceptor cell differentiationGO:004653020.012
modification dependent protein catabolic processGO:00199412090.012
positive regulation of intracellular transportGO:00323881040.012
matingGO:000761810.012
response to virusGO:00096151260.012
t cell differentiation in thymusGO:003307740.012
blood vessel morphogenesisGO:00485141620.011
reactive oxygen species metabolic processGO:0072593750.011
head developmentGO:00603221080.011
wnt signaling pathwayGO:00160551560.011
metencephalon developmentGO:002203720.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
protein oligomerizationGO:00512591730.011
cranial nerve developmentGO:002154540.011
negative regulation of organelle organizationGO:00106391260.011
negative regulation of protein processingGO:00109551420.011
nucleocytoplasmic transportGO:00069131760.011
reactive nitrogen species metabolic processGO:200105730.011
somitogenesisGO:000175620.011
establishment of protein localization to organelleGO:00725941720.011
glial cell migrationGO:000834740.011
positive regulation of proteolysisGO:00458621420.011
reactive oxygen species biosynthetic processGO:190340940.011
establishment of tissue polarityGO:000716430.011
proteasomal protein catabolic processGO:00104981760.011
associative learningGO:000830610.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
response to organic cyclic compoundGO:00140702040.011
regulation of cell projection organizationGO:00313441070.011
cardiac muscle cell contractionGO:008600340.011
regulation of defense responseGO:00313471540.011
epithelium migrationGO:00901321190.011
regulation of dephosphorylationGO:0035303960.011
regulation of cytoplasmic transportGO:19036491490.011
response to hypoxiaGO:0001666960.011
organ morphogenesisGO:00098871470.011
Fly
nucleoside phosphate biosynthetic processGO:19012931090.011
tube developmentGO:00352951250.011
circadian behaviorGO:004851220.011
cell cell signalingGO:00072671550.011
nucleoside monophosphate catabolic processGO:00091251590.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
meiosis iGO:000712740.011
activation of immune responseGO:00022531140.011
positive regulation of cell motilityGO:20001471770.011
regulation of protein serine threonine kinase activityGO:00719001790.011
somatic muscle developmentGO:000752510.011
behaviorGO:00076101120.011
negative regulation of transferase activityGO:00513481240.011
ameboidal type cell migrationGO:00016671350.011
primary neural tube formationGO:001402030.011
tissue migrationGO:00901301190.011
regulation of cell cycle phase transitionGO:19019871260.011
epithelial cell differentiationGO:00308551410.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
neuron projection regenerationGO:003110210.011
regulation of cell activationGO:00508651250.011
somatic stem cell maintenanceGO:003501940.011
neural tube closureGO:000184330.011
inner ear morphogenesisGO:004247240.011
regulation of intracellular protein transportGO:00331571230.011
organelle fissionGO:00482851490.011
defense response to fungusGO:005083240.011
divalent inorganic cation transportGO:00725111580.011
tissue regenerationGO:004224630.010
regulation of rho gtpase activityGO:0032319660.010
Fly
post embryonic organ developmentGO:004856910.010
Fly
nucleus localizationGO:005164710.010
sulfur compound metabolic processGO:00067901010.010
positive regulation of cytokine productionGO:00018191670.010
peptidyl lysine modificationGO:00182051440.010
vasculature developmentGO:00019441810.010
thymus developmentGO:004853830.010
regulation of transmembrane transportGO:00347621390.010
asymmetric neuroblast divisionGO:005505910.010
plasma membrane organizationGO:00070091150.010
interspecies interaction between organismsGO:00444191560.010
mitochondrion organizationGO:00070051560.010
cerebellum developmentGO:002154920.010
establishment of planar polarityGO:000173630.010
neural crest cell developmentGO:001403230.010
blood vessel developmentGO:00015681720.010
epidermis morphogenesisGO:004873030.010
immune effector processGO:00022521590.010
neuronal stem cell divisionGO:003644510.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
rna splicingGO:00083801310.010
cellular calcium ion homeostasisGO:00068741170.010
protein acylationGO:00435431380.010
monovalent inorganic cation transportGO:00156721280.010
asymmetric stem cell divisionGO:009872210.010
regulation of apoptotic signaling pathwayGO:20012331750.010
regulation of rho protein signal transductionGO:0035023790.010
Fly
myosin filament assemblyGO:003103420.010
Worm

PLEKHG2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.031
disease of metabolismDOID:00146672950.023
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.019
connective tissue diseaseDOID:651090.017
central nervous system diseaseDOID:3311860.017
inherited metabolic disorderDOID:6552420.017
bone diseaseDOID:0080001880.015
immune system diseaseDOID:29141550.015
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.013
muscular diseaseDOID:00800001140.013
retinal diseaseDOID:56791180.011
neurodegenerative diseaseDOID:12891020.011
brain diseaseDOID:936730.011
myopathyDOID:4231040.011
muscle tissue diseaseDOID:661130.011
bone development diseaseDOID:0080006550.011
retinal degenerationDOID:8466890.010