Homo sapiens

48 known processes

USP49

ubiquitin specific peptidase 49

(Aliases: MGC20741)

USP49 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein deubiquitinationGO:0016579790.194
protein modification by small protein removalGO:0070646920.131
post embryonic developmentGO:000979120.104
protein catabolic processGO:00301633250.096
Human
chromatin organizationGO:00063253510.096
cellular macromolecule catabolic processGO:00442653800.095
Human
chromatin modificationGO:00165682980.088
protein modification by small protein conjugationGO:00324463420.081
Human
histone modificationGO:00165702510.070
negative regulation of protein metabolic processGO:00512483910.063
Human
rna processingGO:00063962550.063
protein processingGO:00164852260.060
Human
modification dependent macromolecule catabolic processGO:00436322120.060
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.058
Human
cellular protein catabolic processGO:00442572610.053
Human
protein ubiquitinationGO:00165673140.053
Human
dna repairGO:00062811980.049
Human
organelle fissionGO:00482851490.048
Human
regulation of transferase activityGO:00513383550.047
Human
mitotic cell cycleGO:00002783260.046
Human
regulation of mitosisGO:0007088630.046
Human
segmentationGO:003528240.045
regulation of proteasomal protein catabolic processGO:0061136870.045
Human
system processGO:00030083490.042
proteasomal protein catabolic processGO:00104981760.042
Human
cytoplasmic transportGO:00164823790.042
regulation of cell cycle processGO:00105642660.040
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.040
Human
regulation of protein processingGO:00706131500.040
Human
mrna metabolic processGO:00160711750.038
regulation of protein maturationGO:19033171500.037
Human
negative regulation of protein maturationGO:19033181420.037
Human
regulation of proteolysisGO:00301622930.037
Human
multicellular organismal agingGO:001025930.037
oogenesisGO:004847720.036
regulation of cell cycleGO:00517263930.036
Human
regulation of ligase activityGO:0051340290.035
Human
negative regulation of protein modification processGO:00314002000.035
Human
nuclear transportGO:00511691790.034
negative regulation of catalytic activityGO:00430863350.034
Human
nucleocytoplasmic transportGO:00069131760.033
regulation of cell migrationGO:00303342890.033
locomotory behaviorGO:000762610.033
cell divisionGO:00513011680.033
Human
mitotic sister chromatid separationGO:0051306180.031
Human
determination of adult lifespanGO:000834020.031
female gamete generationGO:000729220.031
rhythmic behaviorGO:000762220.030
histone deubiquitinationGO:0016578160.029
associative learningGO:000830610.029
chromosome segregationGO:00070591140.028
Human
regulation of cell motilityGO:20001452990.028
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.028
Human
regulation of cell divisionGO:00513021160.028
Human
response to abiotic stimulusGO:00096283360.028
chromosome separationGO:0051304230.027
Human
cell cycle phase transitionGO:00447701730.027
Human
intracellular protein transportGO:00068862700.027
amine metabolic processGO:0009308440.027
metal ion transportGO:00300012720.027
single organism cellular localizationGO:19025803320.027
negative regulation of organelle organizationGO:00106391260.026
Human
regulation of mitotic cell cycleGO:00073461890.026
Human
mrna splicing via spliceosomeGO:0000398890.026
regulation of intracellular transportGO:00323861950.026
blastoderm segmentationGO:000735020.026
regulation of ion transportGO:00432691890.025
cellular amino acid metabolic processGO:00065201160.025
regulation of neural precursor cell proliferationGO:200017740.025
regulation of protein localizationGO:00328802960.025
negative regulation of cell deathGO:00605483450.025
nuclear divisionGO:00002801280.025
Human
regulation of nuclear divisionGO:0051783650.025
Human
posttranscriptional regulation of gene expressionGO:00106082130.025
Human
regulation of ubiquitin protein transferase activityGO:0051438280.025
Human
negative regulation of gliogenesisGO:001401430.025
dephosphorylationGO:00163112090.025
regulation of locomotionGO:00400123290.024
regulation of protein catabolic processGO:00421761550.024
Human
spermatid developmentGO:000728640.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
regulation of chromosome segregationGO:0051983440.024
Human
neuromuscular junction developmentGO:000752830.024
mitotic cell cycle phase transitionGO:00447721620.024
Human
negative regulation of cell cycleGO:00457861930.024
Human
regulation of cellular component movementGO:00512703340.023
ras protein signal transductionGO:0007265730.023
anterior posterior axis specificationGO:000994820.023
histone h2b conserved c terminal lysine deubiquitinationGO:003561610.023
negative regulation of catabolic processGO:00098951040.023
Human
regulation of protein stabilityGO:0031647870.023
Human
regenerationGO:003109940.023
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.023
Human
positive regulation of phosphorylationGO:00423273940.022
protein localization to organelleGO:00333652800.022
positive regulation of immune system processGO:00026842830.022
neurological system processGO:00508771630.022
rna splicingGO:00083801310.022
circadian behaviorGO:004851220.022
oocyte differentiationGO:000999420.022
regulation of glial cell differentiationGO:004568530.022
cation transportGO:00068123310.022
regulation of chromosome organizationGO:00330441030.021
Human
negative regulation of proteolysisGO:00458611320.021
Human
spermatid differentiationGO:004851540.021
negative regulation of chromosome organizationGO:2001251480.021
Human
positive regulation of cellular component organizationGO:00511303760.021
cellular homeostasisGO:00197251960.021
regulation of protein ubiquitinationGO:0031396950.021
Human
negative regulation of cellular protein metabolic processGO:00322693530.021
Human
regulation of mitotic metaphase anaphase transitionGO:0030071260.021
Human
metaphase anaphase transition of cell cycleGO:0044784210.021
Human
ribonucleoside catabolic processGO:00424544060.021
metaphase anaphase transition of mitotic cell cycleGO:0007091210.021
Human
negative regulation of proteasomal protein catabolic processGO:1901799320.021
Human
positive regulation of transportGO:00510503360.021
sister chromatid segregationGO:0000819540.021
Human
spindle assembly checkpointGO:0071173170.020
inorganic ion transmembrane transportGO:00986602310.020
negative regulation of programmed cell deathGO:00430693210.020
purine ribonucleoside metabolic processGO:00461284370.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
adult locomotory behaviorGO:000834410.020
cellular response to dna damage stimulusGO:00069743790.020
Human
negative regulation of cell cycle phase transitionGO:1901988890.020
Human
cellular ketone metabolic processGO:0042180800.020
regulation of protein transportGO:00512232130.020
regulation of cellular amino acid metabolic processGO:000652160.020
ribonucleoside triphosphate metabolic processGO:00091994120.020
negative regulation of cellular protein catabolic processGO:1903363380.020
Human
nitrogen compound transportGO:00717051910.020
memoryGO:000761330.020
regulation of cell differentiationGO:00455953930.020
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.020
Human
transmembrane transportGO:00550853990.020
regulation of cellular amine metabolic processGO:0033238110.020
cation homeostasisGO:00550801890.020
glycosyl compound catabolic processGO:19016584130.020
negative regulation of apoptotic processGO:00430663160.020
membrane organizationGO:00610242920.019
peripheral nervous system developmentGO:000742220.019
sensory perceptionGO:00076001030.019
positive regulation of cellular amine metabolic processGO:003324070.019
protein maturationGO:00516042330.019
Human
cation transmembrane transportGO:00986552380.019
response to oxygen containing compoundGO:19017003690.019
regulation of purine nucleotide metabolic processGO:19005422640.019
protein targetingGO:00066051870.019
regulation of cytoplasmic transportGO:19036491490.019
ion transmembrane transportGO:00342203380.019
regulation of mitotic cell cycle phase transitionGO:19019901180.019
Human
nervous system developmentGO:00073992930.019
negative regulation of mitotic cell cycle phase transitionGO:1901991850.018
Human
sleepGO:003043120.018
nucleoside phosphate catabolic processGO:19012924120.018
regulation of cell developmentGO:00602841610.018
regulation of establishment of protein localizationGO:00702012420.018
actin filament based processGO:00300292240.018
cardiac muscle cell contractionGO:008600340.018
nerve developmentGO:002167540.018
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.018
morphogenesis of embryonic epitheliumGO:001633140.018
regulation of mitotic sister chromatid segregationGO:0033047270.018
Human
cellular chemical homeostasisGO:00550821800.018
tripartite regional subdivisionGO:000735120.018
circadian sleep wake cycleGO:004274520.018
immune responseGO:00069553070.017
protein localization to nucleusGO:00345041360.017
regulation of metaphase anaphase transition of cell cycleGO:1902099260.017
Human
regulation of protein modification by small protein conjugation or removalGO:19033201070.017
Human
regulation of cellular response to stressGO:00801352440.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
cell morphogenesisGO:00009022960.017
oocyte developmentGO:004859910.017
establishment of protein localization to organelleGO:00725941720.017
anterior posterior axis specification embryoGO:000859520.017
inorganic cation transmembrane transportGO:00986621940.017
positive regulation of hydrolase activityGO:00513453310.017
regulation of meiotic cell cycleGO:005144540.017
maintenance of locationGO:00512351120.017
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.017
negative regulation of intracellular signal transductionGO:19025321830.017
ubiquitin dependent protein catabolic processGO:00065112060.016
Human
chemical homeostasisGO:00488783060.016
regulation of nucleotide catabolic processGO:00308112050.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
positive regulation of protein phosphorylationGO:00019343130.016
reactive oxygen species metabolic processGO:0072593750.016
neurogenesisGO:00220081690.016
negative regulation of wnt signaling pathwayGO:0030178690.016
negative regulation of protein processingGO:00109551420.016
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.016
small gtpase mediated signal transductionGO:0007264780.016
divalent inorganic cation transportGO:00725111580.016
negative regulation of developmental processGO:00510932470.016
calcium ion transportGO:00068161470.016
positive regulation of intracellular transportGO:00323881040.016
positive regulation of nucleotide catabolic processGO:00308131850.016
mitotic cell cycle processGO:19030472860.016
Human
response to nitrogen compoundGO:19016981840.016
divalent metal ion transportGO:00708381520.016
positive regulation of apoptotic processGO:00430652460.016
stem cell divisionGO:001714520.016
cellular response to endogenous stimulusGO:00714953360.016
ncrna metabolic processGO:00346601080.016
cell projection organizationGO:00300302520.015
protein polyubiquitinationGO:00002091100.015
forebrain neuron differentiationGO:002187930.015
regulation of purine nucleotide catabolic processGO:00331212050.015
negative regulation of phosphorus metabolic processGO:00105632670.015
protein importGO:00170381300.015
regulation of protein kinase activityGO:00458592890.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
oxidation reduction processGO:00551143960.015
negative regulation of multicellular organismal processGO:00512413170.015
anion transportGO:00068201610.015
positive regulation of cell proliferationGO:00082843010.015
negative regulation of phosphate metabolic processGO:00459362670.015
negative regulation of cellular amine metabolic processGO:003323930.015
cellular amine metabolic processGO:0044106410.015
apoptotic signaling pathwayGO:00971902680.015
multicellular organismal signalingGO:0035637340.015
tissue regenerationGO:004224630.015
spinal cord developmentGO:002151040.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
generation of neuronsGO:00486991520.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
nucleic acid phosphodiester bond hydrolysisGO:00903051020.015
biological adhesionGO:00226103310.015
protein oligomerizationGO:00512591730.015
regulation of sister chromatid segregationGO:0033045270.015
Human
negative regulation of protein catabolic processGO:0042177590.015
Human
cellular response to organic cyclic compoundGO:00714071270.015
reactive nitrogen species metabolic processGO:200105730.015
negative regulation of protein ubiquitinationGO:0031397350.015
Human
endomembrane system organizationGO:00102561960.014
sensory perception of smellGO:000760820.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
startle responseGO:000196430.014
multi organism cellular processGO:00447641560.014
protein targeting to nucleusGO:00447441040.014
regulation of intracellular protein transportGO:00331571230.014
detection of stimulusGO:0051606850.014
positive regulation of cytoplasmic transportGO:1903651820.014
meiotic chromosome segregationGO:004513240.014
embryonic epithelial tube formationGO:000183840.014
metal ion homeostasisGO:00550651690.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of synaptic plasticityGO:004816730.014
wnt signaling pathwayGO:00160551560.014
regulation of odontogenesisGO:004248140.014
cellular macromolecular complex assemblyGO:00346223240.014
cellular lipid metabolic processGO:00442553030.014
lipid metabolic processGO:00066293810.014
cellular metal ion homeostasisGO:00068751460.014
actin mediated cell contractionGO:0070252120.014
cell adhesionGO:00071553250.014
covalent chromatin modificationGO:00165692540.014
positive regulation of protein transportGO:00512221350.014
regulation of ras protein signal transductionGO:00465781550.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
sequestering of metal ionGO:0051238240.014
mitotic cell cycle checkpointGO:0007093680.014
response to fungusGO:000962040.014
circadian sleep wake cycle sleepGO:005080220.014
hindbrain developmentGO:003090230.014
response to other organismGO:00517072610.014
secretion by cellGO:00329402260.014
secretionGO:00469032540.014
regulation of membrane potentialGO:0042391950.014
microtubule based processGO:00070172100.014
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.014
Human
forebrain generation of neuronsGO:002187230.014
regulation of nucleotide metabolic processGO:00061402690.013
positive regulation of cell differentiationGO:00455972110.013
response to organic cyclic compoundGO:00140702040.013
monovalent inorganic cation transportGO:00156721280.013
regulation of cell cycle phase transitionGO:19019871260.013
Human
rna interferenceGO:001624640.013
regulation of dephosphorylationGO:0035303960.013
compound eye developmentGO:004874910.013
positive regulation of programmed cell deathGO:00430682490.013
ion homeostasisGO:00508012300.013
single organism nuclear importGO:19025931040.013
positive regulation of cell deathGO:00109422630.013
vesicle mediated transportGO:00161923710.013
negative regulation of cell differentiationGO:00455961710.013
response to external biotic stimulusGO:00432072610.013
organelle assemblyGO:00709251760.013
rho protein signal transductionGO:0007266260.013
protein k48 linked ubiquitinationGO:0070936380.013
regulation of kinase activityGO:00435493140.013
negative regulation of cell divisionGO:0051782310.013
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.013
actin filament based movementGO:0030048170.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
cell developmentGO:00484683280.013
regulation of cellular ketone metabolic processGO:0010565500.013
purine ribonucleoside catabolic processGO:00461303980.013
ribonucleoprotein complex biogenesisGO:00226131160.013
negative regulation of cell proliferationGO:00082852280.013
regulation of metal ion transportGO:00109591200.013
regulation of response to external stimulusGO:00321012220.013
microtubule cytoskeleton organizationGO:00002261760.012
cerebellum developmentGO:002154920.012
positive regulation of organelle organizationGO:00106381950.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.012
Human
purine ribonucleotide catabolic processGO:00091544040.012
nuclear importGO:00511701060.012
lipid biosynthetic processGO:00086101770.012
positive regulation of developmental processGO:00510943140.012
innate immune responseGO:00450871780.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
syncytium formation by plasma membrane fusionGO:000076820.012
neural tube closureGO:000184330.012
tube closureGO:006060630.012
defense responseGO:00069523150.012
regulation of transmembrane transportGO:00347621390.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
regulation of dna metabolic processGO:00510521530.012
cellular component morphogenesisGO:00329893140.012
regulation of cell growthGO:00015581350.012
neural tube formationGO:000184130.012
metencephalon developmentGO:002203720.012
response to fibroblast growth factorGO:0071774390.012
sensory perception of painGO:001923340.012
limbic system developmentGO:002176130.012
epidermis morphogenesisGO:004873030.012
regulation of cytokine productionGO:00018172320.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of circadian sleep wake cycleGO:004274920.012
negative regulation of hydrolase activityGO:00513461820.011
photoreceptor cell differentiationGO:004653020.011
sequestering of calcium ionGO:0051208170.011
matingGO:000761810.011
cell projection morphogenesisGO:00488581290.011
cell part morphogenesisGO:00329901370.011
methylationGO:00322591060.011
protein import into nucleusGO:00066061040.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
embryo developmentGO:00097901230.011
protein autophosphorylationGO:00467771230.011
regulation of cell adhesionGO:00301551660.011
positive regulation of nucleoside metabolic processGO:00459791860.011
single organism membrane organizationGO:00448022680.011
regulation of gtpase activityGO:00430871800.011
circadian sleep wake cycle processGO:002241020.011
cellular calcium ion homeostasisGO:00068741170.011
hair follicle morphogenesisGO:003106920.011
negative regulation of transferase activityGO:00513481240.011
Human
negative regulation of smoothened signaling pathwayGO:004587930.011
response to axon injuryGO:004867810.011
neural crest cell developmentGO:001403230.011
ventral spinal cord developmentGO:002151710.011
response to growth factorGO:00708482050.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
response to organonitrogen compoundGO:00102431560.011
ncrna processingGO:0034470830.011
cytokine productionGO:00018162470.011
neurotransmitter secretionGO:000726940.011
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of immune responseGO:00507762010.011
positive regulation of cellular component biogenesisGO:00440891580.011
negative regulation of mitotic sister chromatid separationGO:2000816170.011
Human
macromolecule methylationGO:0043414970.011
endosomal transportGO:00161971290.011
response to hypoxiaGO:0001666960.011
rna phosphodiester bond hydrolysisGO:0090501350.011
regulation of calcium ion transportGO:0051924790.011
interspecies interaction between organismsGO:00444191560.011
primary neural tube formationGO:001402030.011
negative regulation of chromosome segregationGO:0051985180.010
Human
mitochondrion organizationGO:00070051560.010
modification dependent protein catabolic processGO:00199412090.010
Human
cell differentiation in spinal cordGO:002151510.010
cell fate determinationGO:000170930.010
regulation of cellular protein catabolic processGO:1903362960.010
Human
response to biotic stimulusGO:00096072760.010
sensory perception of light stimulusGO:0050953350.010
regulation of endopeptidase activityGO:00525481700.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
negative regulation of response to external stimulusGO:0032102830.010
regulation of meiosisGO:004002030.010
regulation of cytoskeleton organizationGO:00514931770.010
positive regulation of transferase activityGO:00513472270.010
response to virusGO:00096151260.010
calcium ion homeostasisGO:00550741220.010
motor neuron axon guidanceGO:000804520.010
positive regulation of synaptic transmissionGO:005080640.010
response to nutrient levelsGO:0031667810.010
cellular response to abiotic stimulusGO:00712141170.010
cellular cation homeostasisGO:00300031630.010
visual behaviorGO:000763220.010
organ formationGO:004864530.010
myoblast fusionGO:000752010.010
positive regulation of cytokine productionGO:00018191670.010

USP49 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.024
sensory system diseaseDOID:00501552030.024
disease of mental healthDOID:150700.023
disease of cellular proliferationDOID:145661740.023
cancerDOID:1621670.022
organ system cancerDOID:00506861640.022
musculoskeletal system diseaseDOID:172230.021
disease of metabolismDOID:00146672950.020
central nervous system diseaseDOID:3311860.019
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
retinal diseaseDOID:56791180.016
inherited metabolic disorderDOID:6552420.015
connective tissue diseaseDOID:651090.012
bone diseaseDOID:0080001880.012
muscle tissue diseaseDOID:661130.011
myopathyDOID:4231040.011
muscular diseaseDOID:00800001140.011
brain diseaseDOID:936730.011
retinal degenerationDOID:8466890.011