Homo sapiens

17 known processes

USP46

ubiquitin specific peptidase 46

(Aliases: FLJ39393,FLJ14283,FLJ11850,FLJ12552)

USP46 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
limbic system developmentGO:002176130.777
hippocampus developmentGO:002176610.620
protein dephosphorylationGO:0006470810.243
protein deubiquitinationGO:0016579790.205
cellular amino acid metabolic processGO:00065201160.195
cellular amino acid biosynthetic processGO:0008652300.159
protein modification by small protein removalGO:0070646920.125
pallium developmentGO:0021543100.119
cellular response to dna damage stimulusGO:00069743790.113
negative regulation of intracellular signal transductionGO:19025321830.111
purine ribonucleotide catabolic processGO:00091544040.107
organonitrogen compound biosynthetic processGO:19015662000.099
organophosphate catabolic processGO:00464344300.097
forebrain developmentGO:0030900260.096
carboxylic acid biosynthetic processGO:0046394970.081
dephosphorylationGO:00163112090.081
glycosyl compound catabolic processGO:19016584130.078
female gamete generationGO:000729220.077
response to unfolded proteinGO:0006986240.073
head developmentGO:00603221080.072
double strand break repairGO:00063021010.071
purine ribonucleoside metabolic processGO:00461284370.069
nucleoside triphosphate catabolic processGO:00091433940.067
organic acid biosynthetic processGO:0016053970.066
regulation of epithelial cell proliferationGO:00506781130.064
ribonucleoside catabolic processGO:00424544060.064
negative regulation of cellular protein metabolic processGO:00322693530.064
nervous system developmentGO:00073992930.063
positive regulation of epithelial cell proliferationGO:0050679650.062
purine nucleoside catabolic processGO:00061523980.062
purine containing compound catabolic processGO:00725234110.057
morphogenesis of embryonic epitheliumGO:001633140.056
nucleoside triphosphate metabolic processGO:00091414220.055
positive regulation of cell proliferationGO:00082843010.054
brain developmentGO:0007420970.053
positive regulation of cell sizeGO:004579330.051
ribonucleotide catabolic processGO:00092614050.051
central nervous system developmentGO:00074171230.050
dna repairGO:00062811980.050
protein ubiquitinationGO:00165673140.049
small molecule biosynthetic processGO:00442831570.048
positive regulation of catabolic processGO:00098963100.047
negative regulation of protein metabolic processGO:00512483910.045
cell cycle checkpointGO:00000751170.045
telencephalon developmentGO:0021537170.044
post embryonic developmentGO:000979120.042
oogenesisGO:004847720.042
regulation of cellular component sizeGO:0032535820.041
guanosine containing compound metabolic processGO:19010682440.041
regulation of anatomical structure sizeGO:00900661010.041
regulation of dna metabolic processGO:00510521530.041
posttranscriptional regulation of gene expressionGO:00106082130.041
translationGO:00064121320.040
amine metabolic processGO:0009308440.039
cellular homeostasisGO:00197251960.039
cytoplasmic transportGO:00164823790.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.039
dna integrity checkpointGO:0031570710.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
locomotory behaviorGO:000762610.037
neuromuscular junction developmentGO:000752830.035
response to radiationGO:00093141510.035
cellular response to external stimulusGO:00714961110.035
purine ribonucleoside triphosphate catabolic processGO:00092073910.035
protein modification by small protein conjugationGO:00324463420.034
memoryGO:000761330.034
cellular response to nutrient levelsGO:0031669690.033
ribonucleoside triphosphate metabolic processGO:00091994120.033
secretion by cellGO:00329402260.033
response to topologically incorrect proteinGO:0035966290.032
response to extracellular stimulusGO:0009991850.032
organ morphogenesisGO:00098871470.032
positive regulation of apoptotic processGO:00430652460.031
purine ribonucleoside catabolic processGO:00461303980.031
cell morphogenesisGO:00009022960.031
regulation of cellular amino acid metabolic processGO:000652160.031
cellular response to topologically incorrect proteinGO:0035967190.031
nucleoside phosphate catabolic processGO:19012924120.031
negative regulation of catalytic activityGO:00430863350.030
mitotic cell cycleGO:00002783260.030
gtp metabolic processGO:00460392390.030
purine nucleotide catabolic processGO:00061954050.030
positive regulation of cellular component organizationGO:00511303760.030
regulation of purine nucleotide metabolic processGO:19005422640.030
system processGO:00030083490.030
cell agingGO:0007569520.030
growthGO:00400072020.029
regulation of cellular response to stressGO:00801352440.029
cellular response to starvationGO:0009267580.029
multicellular organismal agingGO:001025930.029
translational initiationGO:0006413480.029
regulation of protein kinase b signalingGO:0051896610.028
chronological cell agingGO:000130020.028
regulation of protein kinase activityGO:00458592890.028
regulation of translational initiationGO:0006446240.028
positive regulation of programmed cell deathGO:00430682490.028
negative regulation of growthGO:0045926970.028
positive regulation of hydrolase activityGO:00513453310.028
response to endoplasmic reticulum stressGO:0034976490.027
secretionGO:00469032540.027
nucleotide catabolic processGO:00091664080.027
establishment or maintenance of bipolar cell polarityGO:006124520.026
positive regulation of purine nucleotide catabolic processGO:00331231850.026
regulation of purine nucleotide catabolic processGO:00331212050.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
regulation of cell cycle processGO:00105642660.026
positive regulation of cell deathGO:00109422630.026
response to abiotic stimulusGO:00096283360.025
regulation of kinase activityGO:00435493140.025
positive regulation of phosphorylationGO:00423273940.025
cellular response to extracellular stimulusGO:0031668720.025
cellular ketone metabolic processGO:0042180800.025
cell developmentGO:00484683280.025
positive regulation of nucleotide metabolic processGO:00459812300.025
proteasomal protein catabolic processGO:00104981760.025
regulation of protein localizationGO:00328802960.025
purine ribonucleoside monophosphate catabolic processGO:00091691580.025
membrane organizationGO:00610242920.024
regulation of protein modification by small protein conjugation or removalGO:19033201070.024
protein kinase c signalingGO:0070528170.024
cellular amine metabolic processGO:0044106410.024
purine nucleoside triphosphate metabolic processGO:00091444120.024
regulation of growthGO:00400081650.024
regulation of translationGO:0006417890.024
regulation of transferase activityGO:00513383550.024
endomembrane system organizationGO:00102561960.024
guanosine containing compound catabolic processGO:19010692390.024
regulation of cytoskeleton organizationGO:00514931770.023
oocyte developmentGO:004859910.023
regulation of cell differentiationGO:00455953930.023
regulation of nucleotide metabolic processGO:00061402690.023
regulation of protein ubiquitinationGO:0031396950.023
regulation of mapk cascadeGO:00434082620.023
regulation of cell growthGO:00015581350.023
positive regulation of cellular amine metabolic processGO:003324070.023
positive regulation of gtpase activityGO:00435471660.022
negative regulation of protein modification processGO:00314002000.022
regulation of cellular amine metabolic processGO:0033238110.022
vesicle mediated transportGO:00161923710.022
atp catabolic processGO:00062001570.022
regulation of ras protein signal transductionGO:00465781550.022
negative regulation of multicellular organismal processGO:00512413170.022
negative regulation of phosphorus metabolic processGO:00105632670.022
cell adhesionGO:00071553250.021
cellular component morphogenesisGO:00329893140.021
macromolecular complex disassemblyGO:0032984600.021
Yeast
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.021
anterior posterior axis specificationGO:000994820.021
transmembrane transportGO:00550853990.021
regulation of cell morphogenesisGO:00226041530.020
regulation of nucleoside metabolic processGO:00091182090.020
regulation of anatomical structure morphogenesisGO:00226032860.020
regulation of nucleotide catabolic processGO:00308112050.020
positive regulation of immune system processGO:00026842830.020
determination of adult lifespanGO:000834020.020
protein processingGO:00164852260.020
long term memoryGO:000761620.020
plasma membrane organizationGO:00070091150.020
ras protein signal transductionGO:0007265730.020
oocyte differentiationGO:000999420.020
neurotransmitter secretionGO:000726940.020
ribonucleoside monophosphate catabolic processGO:00091581580.020
regulation of small gtpase mediated signal transductionGO:00510561560.020
regulation of cell motilityGO:20001452990.019
cation transportGO:00068123310.019
signal transduction by phosphorylationGO:00230142970.019
inner ear morphogenesisGO:004247240.019
cellular macromolecular complex assemblyGO:00346223240.019
cellular protein catabolic processGO:00442572610.019
negative regulation of cellular component organizationGO:00511292350.019
immune responseGO:00069553070.019
regulation of cellular component biogenesisGO:00440872810.019
positive regulation of cellular catabolic processGO:00313312840.019
regulation of gtp catabolic processGO:00331241800.019
positive regulation of cell differentiationGO:00455972110.019
negative regulation of cell growthGO:0030308830.019
positive regulation of nucleoside metabolic processGO:00459791860.019
positive regulation of protein kinase activityGO:00458601900.019
lipid metabolic processGO:00066293810.018
chemical homeostasisGO:00488783060.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
tripartite regional subdivisionGO:000735120.018
regulation of cellular ketone metabolic processGO:0010565500.018
mitotic cell cycle processGO:19030472860.018
segmentationGO:003528240.018
regulation of cell cycleGO:00517263930.018
gtp catabolic processGO:00061842370.018
cellular component disassemblyGO:0022411920.018
Yeast
cellular macromolecule catabolic processGO:00442653800.018
purine nucleoside monophosphate metabolic processGO:00091261860.018
protein catabolic processGO:00301633250.018
negative regulation of protein kinase b signalingGO:0051898170.018
single organism membrane organizationGO:00448022680.018
ion transmembrane transportGO:00342203380.018
metal ion transportGO:00300012720.018
positive regulation of kinase activityGO:00336742040.018
embryonic organ developmentGO:0048568360.018
regulation of homeostatic processGO:00328441210.018
Yeast
establishment of tissue polarityGO:000716430.018
intracellular protein transportGO:00068862700.018
mapk cascadeGO:00001652880.017
adult locomotory behaviorGO:000834410.017
endoplasmic reticulum unfolded protein responseGO:0030968160.017
cellular response to radiationGO:0071478650.017
establishment of planar polarityGO:000173630.017
cytokine productionGO:00018162470.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
response to nutrient levelsGO:0031667810.017
negative regulation of programmed cell deathGO:00430693210.017
carbohydrate metabolic processGO:00059752070.017
er nucleus signaling pathwayGO:0006984230.017
protein kinase b signalingGO:0043491690.017
positive regulation of cellular component biogenesisGO:00440891580.017
cell growthGO:00160491600.017
generation of neuronsGO:00486991520.017
regulation of cellular component movementGO:00512703340.016
regulation of rho protein signal transductionGO:0035023790.016
microtubule based processGO:00070172100.016
positive regulation of ras gtpase activityGO:00323201170.016
negative regulation of phosphorylationGO:00423261740.016
epithelium developmentGO:00604292270.016
oxidation reduction processGO:00551143960.016
negative regulation of cell deathGO:00605483450.016
positive regulation of gtp catabolic processGO:00331261660.016
response to starvationGO:0042594590.016
regulation of protein transportGO:00512232130.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
cation transmembrane transportGO:00986552380.016
blastoderm segmentationGO:000735020.016
negative regulation of phosphate metabolic processGO:00459362670.016
nucleoside monophosphate metabolic processGO:00091231910.016
nucleoside catabolic processGO:00091644080.016
monocarboxylic acid metabolic processGO:00327871850.016
double strand break repair via homologous recombinationGO:0000724500.016
carbohydrate derivative biosynthetic processGO:19011372070.016
positive regulation of developmental processGO:00510943140.016
regulation of ras gtpase activityGO:00323181280.016
cell divisionGO:00513011680.016
hair cell differentiationGO:003531520.016
response to other organismGO:00517072610.016
cardiovascular system developmentGO:00723582620.016
negative regulation of translationGO:0017148370.015
regulation of cell projection organizationGO:00313441070.015
rho protein signal transductionGO:0007266260.015
microtubule cytoskeleton organizationGO:00002261760.015
spermatid differentiationGO:004851540.015
protein polyubiquitinationGO:00002091100.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
regulation of secretionGO:00510461940.015
rhythmic processGO:0048511310.015
cellular response to abiotic stimulusGO:00712141170.015
nucleoside monophosphate catabolic processGO:00091251590.015
protein monoubiquitinationGO:0006513390.015
cerebral cortex cell migrationGO:002179530.015
single organism cellular localizationGO:19025803320.015
protein oligomerizationGO:00512591730.015
innate immune responseGO:00450871780.015
nucleus localizationGO:005164710.015
single organism cell adhesionGO:00986021790.015
male sex differentiationGO:0046661250.014
positive regulation of organelle organizationGO:00106381950.014
cell projection organizationGO:00300302520.014
positive regulation of rho gtpase activityGO:0032321560.014
dna recombinationGO:0006310770.014
negative regulation of apoptotic processGO:00430663160.014
positive regulation of transferase activityGO:00513472270.014
cellular lipid metabolic processGO:00442553030.014
stem cell divisionGO:001714520.014
tube closureGO:006060630.014
neural tube closureGO:000184330.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
sulfur compound metabolic processGO:00067901010.014
regulation of cell developmentGO:00602841610.014
neurological system processGO:00508771630.014
regulation of locomotionGO:00400123290.014
glycoprotein metabolic processGO:00091001100.014
peptidyl tyrosine phosphorylationGO:00181081700.014
spermatid developmentGO:000728640.014
cell substrate adhesionGO:00315891320.014
glial cell migrationGO:000834740.013
cerebral cortex radially oriented cell migrationGO:002179910.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
cellular chemical homeostasisGO:00550821800.013
cation homeostasisGO:00550801890.013
neurogenesisGO:00220081690.013
peripheral nervous system developmentGO:000742220.013
negative regulation of cell cycleGO:00457861930.013
single organismal cell cell adhesionGO:00163371480.013
defense responseGO:00069523150.013
Mouse
multi organism cellular processGO:00447641560.013
cell morphogenesis involved in differentiationGO:00009041440.013
cell part morphogenesisGO:00329901370.013
regulation of protein complex assemblyGO:00432541470.013
regulation of secretion by cellGO:19035301770.013
cell projection assemblyGO:00300311260.013
ion homeostasisGO:00508012300.013
rhythmic behaviorGO:000762220.013
negative regulation of cellular amine metabolic processGO:003323930.012
actin cytoskeleton organizationGO:00300362070.012
associative learningGO:000830610.012
regulation of response to external stimulusGO:00321012220.012
chromatin modificationGO:00165682980.012
regulation of cell adhesionGO:00301551660.012
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.012
regulation of circadian rhythmGO:0042752110.012
negative regulation of cell proliferationGO:00082852280.012
inorganic cation transmembrane transportGO:00986621940.012
maintenance of cell polarityGO:003001120.012
jnk cascadeGO:0007254800.012
convergent extensionGO:006002610.012
cell junction organizationGO:0034330790.012
circulatory system developmentGO:00723592620.012
peptidyl tyrosine modificationGO:00182121700.012
monovalent inorganic cation transportGO:00156721280.012
modification dependent protein catabolic processGO:00199412090.012
regenerationGO:003109940.012
regulation of cytokine productionGO:00018172320.012
response to external biotic stimulusGO:00432072610.012
inorganic ion transmembrane transportGO:00986602310.012
response to light stimulusGO:0009416870.012
response to oxygen containing compoundGO:19017003690.012
Mouse
anterior posterior axis specification embryoGO:000859520.012
motor neuron axon guidanceGO:000804520.012
regulation of rho gtpase activityGO:0032319660.012
positive regulation of cytoskeleton organizationGO:0051495830.012
maintenance of location in cellGO:0051651620.011
organelle localizationGO:0051640840.011
positive regulation of protein phosphorylationGO:00019343130.011
regulation of apoptotic signaling pathwayGO:20012331750.011
tube developmentGO:00352951250.011
i kappab kinase nf kappab signalingGO:00072491660.011
reactive oxygen species biosynthetic processGO:190340940.011
receptor metabolic processGO:0043112810.011
behaviorGO:00076101120.011
Mouse
hemopoiesisGO:00300971800.011
cell projection morphogenesisGO:00488581290.011
regulation of membrane potentialGO:0042391950.011
sequestering of metal ionGO:0051238240.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of protein processingGO:00706131500.011
endosomal transportGO:00161971290.011
reproductive processGO:00224141060.011
stress activated protein kinase signaling cascadeGO:0031098940.011
positive regulation of cell cycleGO:00457871400.011
regulation of protein serine threonine kinase activityGO:00719001790.011
regulation of establishment of protein localizationGO:00702012420.011
rna processingGO:00063962550.011
small gtpase mediated signal transductionGO:0007264780.011
positive regulation of synaptic transmissionGO:005080640.011
maintenance of locationGO:00512351120.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
negative regulation of hydrolase activityGO:00513461820.011
apoptotic signaling pathwayGO:00971902680.011
sleepGO:003043120.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
regulation of cell morphogenesis involved in differentiationGO:0010769830.011
developmental programmed cell deathGO:001062330.011
interspecies interaction between organismsGO:00444191560.011
protein localization to organelleGO:00333652800.010
embryo developmentGO:00097901230.010
regulation of microtubule cytoskeleton organizationGO:0070507610.010
morphogenesis of an epitheliumGO:0002009600.010
regulation of vesicle mediated transportGO:00606271300.010
protein homooligomerizationGO:00512601000.010
protein maturationGO:00516042330.010
organelle assemblyGO:00709251760.010
regulation of multi organism processGO:00439001570.010
positive regulation of protein transportGO:00512221350.010
nuclear migrationGO:000709710.010
protein k48 linked ubiquitinationGO:0070936380.010
regulation of response to dna damage stimulusGO:2001020940.010
immune system developmentGO:00025201950.010
regulation of immune responseGO:00507762010.010
organic hydroxy compound metabolic processGO:19016151470.010
single organism carbohydrate metabolic processGO:00447231930.010
dna replicationGO:00062601160.010
muscle contractionGO:0006936730.010
reactive oxygen species metabolic processGO:0072593750.010
regulation of actin filament based processGO:00329701410.010
positive regulation of protein serine threonine kinase activityGO:00719021190.010

USP46 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
musculoskeletal system diseaseDOID:172230.018
sensory system diseaseDOID:00501552030.017
organ system cancerDOID:00506861640.016
cancerDOID:1621670.016
disease of cellular proliferationDOID:145661740.016
disease of metabolismDOID:00146672950.014
bone diseaseDOID:0080001880.013
connective tissue diseaseDOID:651090.013