Homo sapiens

254 known processes

BLM

Bloom syndrome, RecQ helicase-like

(Aliases: RECQL3,RECQL2,MGC131618,MGC131620,RECQ2,BS,MGC126616)

BLM biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via homologous recombinationGO:0000724501.000
Fly
dna repairGO:00062811981.000
dna recombinationGO:0006310771.000
cellular response to dna damage stimulusGO:00069743791.000
double strand break repairGO:00063021011.000
recombinational repairGO:0000725501.000
Fly
telomere maintenanceGO:0000723320.999
Mouse
dna replicationGO:00062601160.999
purine ribonucleoside monophosphate catabolic processGO:00091691580.996
dna conformation changeGO:00711031130.995
meiosis iGO:000712740.995
Worm Fly
anatomical structure homeostasisGO:00602491000.992
Mouse
meiotic chromosome segregationGO:004513240.987
Worm
nucleotide excision repairGO:0006289310.986
dna dependent dna replicationGO:0006261440.986
non recombinational repairGO:0000726140.985
Fly
ribonucleoside monophosphate catabolic processGO:00091581580.982
nucleoside monophosphate catabolic processGO:00091251590.966
ribonucleoside monophosphate metabolic processGO:00091611870.962
purine nucleoside catabolic processGO:00061523980.959
purine nucleoside monophosphate catabolic processGO:00091281580.956
telomere organizationGO:0032200330.949
Mouse
organelle fissionGO:00482851490.910
Worm Fly
reciprocal meiotic recombinationGO:000713140.910
Worm Fly
purine nucleoside monophosphate metabolic processGO:00091261860.907
dna geometric changeGO:0032392320.905
mitotic recombinationGO:000631280.888
Mouse
atp metabolic processGO:00460341760.886
ribonucleotide catabolic processGO:00092614050.884
purine ribonucleoside catabolic processGO:00461303980.882
dna double strand break processingGO:0000729100.870
base excision repairGO:0006284210.869
nucleoside monophosphate metabolic processGO:00091231910.862
atp catabolic processGO:00062001570.849
purine nucleoside triphosphate catabolic processGO:00091463920.827
regulation of double strand break repair via homologous recombinationGO:0010569110.821
regulation of dna metabolic processGO:00510521530.816
telomere maintenance via recombinationGO:000072240.816
mismatch repairGO:0006298150.799
glycosyl compound catabolic processGO:19016584130.790
negative regulation of cell cycle processGO:00109481210.780
purine containing compound catabolic processGO:00725234110.765
g2 dna damage checkpointGO:0031572260.755
mitotic dna damage checkpointGO:0044773280.722
mitotic cell cycle processGO:19030472860.704
purine nucleotide catabolic processGO:00061954050.694
mitotic cell cycle phase transitionGO:00447721620.677
nucleoside phosphate catabolic processGO:19012924120.672
regulation of cell cycle processGO:00105642660.669
nucleotide catabolic processGO:00091664080.637
regulation of cell cycle phase transitionGO:19019871260.633
purine nucleoside triphosphate metabolic processGO:00091444120.629
replication fork processingGO:0031297130.621
purine ribonucleoside monophosphate metabolic processGO:00091671860.611
nucleoside triphosphate catabolic processGO:00091433940.602
cell cycle phase transitionGO:00447701730.600
ribonucleoside catabolic processGO:00424544060.572
purine ribonucleoside metabolic processGO:00461284370.542
nucleoside triphosphate metabolic processGO:00091414220.537
nucleic acid phosphodiester bond hydrolysisGO:00903051020.523
nuclear divisionGO:00002801280.498
Worm Fly
dna catabolic processGO:0006308490.497
reciprocal dna recombinationGO:003582540.496
Worm Fly
double strand break repair via nonhomologous end joiningGO:0006303100.492
Fly
positive regulation of dna metabolic processGO:0051054730.481
nucleoside catabolic processGO:00091644080.474
response to radiationGO:00093141510.470
g2 m transition of mitotic cell cycleGO:0000086410.468
response to abiotic stimulusGO:00096283360.466
ribonucleoside triphosphate metabolic processGO:00091994120.454
chromosome segregationGO:00070591140.441
Worm
ribonucleoside triphosphate catabolic processGO:00092033910.441
regulation of dna replicationGO:0006275680.423
regulation of cell cycleGO:00517263930.419
negative regulation of mitotic cell cycleGO:00459301020.417
organophosphate catabolic processGO:00464344300.398
negative regulation of dna metabolic processGO:0051053570.391
rna dependent dna replicationGO:0006278160.386
dna damage checkpointGO:0000077680.380
meiotic chromosome separationGO:005130730.359
Worm
response to ionizing radiationGO:0010212650.350
regulation of mitotic cell cycleGO:00073461890.342
purine ribonucleoside triphosphate metabolic processGO:00092054110.339
regenerationGO:003109940.335
telomere cappingGO:001623350.330
regulation of double strand break repairGO:2000779220.324
Fly
growthGO:00400072020.310
regulation of g2 m transition of mitotic cell cycleGO:0010389200.305
meiotic cell cycleGO:0051321130.298
Worm Fly
mitochondrion organizationGO:00070051560.283
meiotic nuclear divisionGO:0007126100.282
Worm Fly
somatic diversification of immunoglobulins involved in immune responseGO:000220830.252
mitotic dna integrity checkpointGO:0044774300.244
positive regulation of cell proliferationGO:00082843010.237
Mouse
meiotic cell cycle processGO:190304680.231
Worm Fly
negative regulation of dna biosynthetic processGO:2000279110.230
mitotic sister chromatid segregationGO:0000070530.221
dna integrity checkpointGO:0031570710.214
purine ribonucleotide catabolic processGO:00091544040.211
response to dietary excessGO:000202120.202
sister chromatid segregationGO:0000819540.200
developmental growthGO:0048589480.192
negative regulation of cell cycleGO:00457861930.176
purine ribonucleoside triphosphate catabolic processGO:00092073910.175
regulation of response to dna damage stimulusGO:2001020940.173
Fly
chemical homeostasisGO:00488783060.171
double strand break repair via single strand annealingGO:004500240.165
Fly
mitotic cell cycle checkpointGO:0007093680.161
male meiosisGO:000714010.160
ubiquitin dependent protein catabolic processGO:00065112060.159
microtubule based processGO:00070172100.158
regulation of mitotic cell cycle phase transitionGO:19019901180.154
regulation of dna repairGO:0006282470.154
Fly
gene conversionGO:003582210.151
cellular macromolecular complex assemblyGO:00346223240.145
positive regulation of organelle organizationGO:00106381950.144
negative regulation of cell cycle phase transitionGO:1901988890.143
mitotic nuclear divisionGO:00070671190.142
Worm
cell cycle checkpointGO:00000751170.140
protein dna complex subunit organizationGO:0071824800.140
response to alkaloidGO:0043279200.140
immune system developmentGO:00025201950.136
Mouse
regulation of dna dependent dna replicationGO:0090329190.136
positive regulation of mitotic cell cycleGO:0045931600.135
mitotic cell cycleGO:00002783260.129
dna duplex unwindingGO:0032508300.127
positive regulation of telomere maintenanceGO:003220640.125
telomere maintenance via telomere lengtheningGO:001083390.124
response to oxygen containing compoundGO:19017003690.123
mitotic dna replication checkpointGO:003331420.120
cellular response to abiotic stimulusGO:00712141170.115
protein ubiquitinationGO:00165673140.114
cell developmentGO:00484683280.113
replicative cell agingGO:000130230.112
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.110
negative regulation of organelle organizationGO:00106391260.108
regulation of cellular amino acid metabolic processGO:000652160.107
cellular protein catabolic processGO:00442572610.106
response to uvGO:0009411730.104
cell divisionGO:00513011680.104
negative regulation of mitotic cell cycle phase transitionGO:1901991850.104
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.102
tissue regenerationGO:004224630.101
strand invasionGO:004214820.100
telomere maintenance via telomeraseGO:000700480.095
cellular amine metabolic processGO:0044106410.094
behaviorGO:00076101120.092
response to organic cyclic compoundGO:00140702040.091
negative regulation of developmental processGO:00510932470.088
multicellular organism growthGO:003526480.085
cell agingGO:0007569520.084
regulation of cellular amine metabolic processGO:0033238110.083
somatic diversification of immune receptors via somatic mutationGO:000256610.082
positive regulation of chromosome organizationGO:2001252410.081
positive regulation of programmed cell deathGO:00430682490.081
positive regulation of hydrolase activityGO:00513453310.080
embryo developmentGO:00097901230.077
protein dna complex assemblyGO:0065004640.075
regulation of mitosisGO:0007088630.075
proteolysis involved in cellular protein catabolic processGO:00516032440.073
response to woundingGO:00096111680.073
protein modification by small protein conjugationGO:00324463420.071
lymphocyte activationGO:00466491330.069
Mouse
immune responseGO:00069553070.066
cellular response to ionizing radiationGO:0071479320.062
reproductionGO:0000003630.061
Worm Fly
dna dependent dna replication maintenance of fidelityGO:0045005140.060
cellular response to external stimulusGO:00714961110.060
cellular amino acid metabolic processGO:00065201160.059
positive regulation of phosphorylationGO:00423273940.058
wound healingGO:00420601150.058
dna biosynthetic processGO:0071897400.058
Fly
intrinsic apoptotic signaling pathwayGO:00971931270.057
negative regulation of cellular component organizationGO:00511292350.056
chromatin modificationGO:00165682980.056
response to purine containing compoundGO:0014074400.055
histone threonine phosphorylationGO:003540570.055
b cell activationGO:0042113330.055
regulation of cell divisionGO:00513021160.054
establishment of organelle localizationGO:0051656590.053
negative regulation of cellular protein metabolic processGO:00322693530.053
response to organonitrogen compoundGO:00102431560.053
amine metabolic processGO:0009308440.052
microtubule polymerizationGO:0046785180.052
signal transduction in response to dna damageGO:0042770570.050
cellular macromolecule catabolic processGO:00442653800.049
adaptive immune responseGO:0002250490.049
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.049
regulation of cellular ketone metabolic processGO:0010565500.048
regulation of cytoskeleton organizationGO:00514931770.047
female gamete generationGO:000729220.047
maintenance of dna repeat elementsGO:004357040.046
positive regulation of developmental processGO:00510943140.046
cellular component disassemblyGO:0022411920.046
response to gamma radiationGO:0010332140.046
hematopoietic or lymphoid organ developmentGO:00485341860.045
Mouse
lagging strand elongationGO:000627330.045
sex determinationGO:000753030.044
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.043
metaphase plate congressionGO:0051310180.043
determination of adult lifespanGO:000834020.043
Worm
apoptotic signaling pathwayGO:00971902680.043
negative regulation of dna replicationGO:0008156290.042
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076710.040
regulation of dna recombinationGO:0000018230.040
cellular response to endogenous stimulusGO:00714953360.040
post embryonic developmentGO:000979120.040
dna damage induced protein phosphorylationGO:000697550.039
protein catabolic processGO:00301633250.038
regulation of cell cycle g2 m phase transitionGO:1902749220.038
positive regulation of cell cycle processGO:00900681060.038
negative regulation of cell cycle g2 m phase transitionGO:1902750100.038
cellular ketone metabolic processGO:0042180800.037
head developmentGO:00603221080.035
positive regulation of response to dna damage stimulusGO:2001022430.035
modification dependent protein catabolic processGO:00199412090.034
peptidyl serine modificationGO:00182091060.033
protein polymerizationGO:0051258710.033
humoral immune responseGO:0006959490.033
regulation of chromatin organizationGO:1902275560.032
regulation of microtubule based processGO:0032886740.032
single organism reproductive processGO:0044702980.032
positive regulation of cellular component organizationGO:00511303760.031
leukocyte activationGO:00453211640.030
Mouse
dna unwinding involved in dna replicationGO:000626820.029
cellular response to nitrogen compoundGO:19016991440.029
response to oxidative stressGO:00069791210.029
intracellular mrna localizationGO:000829810.029
regulation of chromosome organizationGO:00330441030.029
defense responseGO:00069523150.028
circulatory system developmentGO:00723592620.028
carbohydrate metabolic processGO:00059752070.028
cellular response to radiationGO:0071478650.028
dna damage response signal transduction by p53 class mediatorGO:0030330440.027
agingGO:0007568660.027
Worm
peptidyl serine phosphorylationGO:00181051010.027
microtubule cytoskeleton organizationGO:00002261760.027
interstrand cross link repairGO:003629730.026
regulation of transferase activityGO:00513383550.026
protein autophosphorylationGO:00467771230.026
carbohydrate derivative biosynthetic processGO:19011372070.026
regulation of protein modification by small protein conjugation or removalGO:19033201070.025
cellular response to organonitrogen compoundGO:00714171240.025
regulation of cellular response to stressGO:00801352440.025
Fly
negative regulation of cell divisionGO:0051782310.025
response to carbohydrateGO:0009743210.025
response to light stimulusGO:0009416870.025
rna catabolic processGO:0006401710.025
regulation of protein ubiquitinationGO:0031396950.024
positive regulation of dna replicationGO:0045740350.024
negative regulation of telomere maintenanceGO:003220590.023
response to extracellular stimulusGO:0009991850.023
negative regulation of apoptotic processGO:00430663160.023
Mouse Worm
regulation of cell differentiationGO:00455953930.023
nervous system developmentGO:00073992930.023
positive regulation of kinase activityGO:00336742040.022
cell cycle g2 m phase transitionGO:0044839430.022
regulation of nuclear divisionGO:0051783650.022
multicellular organism reproductionGO:0032504420.022
positive regulation of cellular amine metabolic processGO:003324070.022
negative regulation of transferase activityGO:00513481240.022
multicellular organismal agingGO:001025930.020
Worm
oocyte maturationGO:000155610.020
response to nutrient levelsGO:0031667810.020
dna catabolic process endonucleolyticGO:0000737370.020
protein acetylationGO:00064731160.020
regulation of nucleoside metabolic processGO:00091182090.019
stem cell differentiationGO:0048863930.019
organelle localizationGO:0051640840.019
negative regulation of programmed cell deathGO:00430693210.019
Mouse Worm
positive regulation of cell cycleGO:00457871400.019
energy homeostasisGO:009700930.019
blastocyst developmentGO:000182430.019
negative regulation of g2 m transition of mitotic cell cycleGO:001097290.019
oocyte developmentGO:004859910.019
positive regulation of catabolic processGO:00098963100.019
cellular response to alkaloidGO:0071312110.018
central nervous system developmentGO:00074171230.018
locomotory behaviorGO:000762610.018
rna processingGO:00063962550.018
protein oligomerizationGO:00512591730.018
regulation of protein catabolic processGO:00421761550.018
multi organism reproductive processGO:0044703540.017
mrna metabolic processGO:00160711750.017
negative regulation of protein maturationGO:19033181420.017
covalent chromatin modificationGO:00165692540.017
response to reactive oxygen speciesGO:0000302610.017
proteasomal protein catabolic processGO:00104981760.017
response to growth factorGO:00708482050.016
protein localization to chromosome telomeric regionGO:007019860.016
regulation of growthGO:00400081650.016
peptidyl lysine modificationGO:00182051440.016
spermatid developmentGO:000728640.016
signal transduction by phosphorylationGO:00230142970.016
leukocyte mediated immunityGO:0002443590.016
response to caffeineGO:003100030.016
epithelium developmentGO:00604292270.016
negative regulation of telomere maintenance via telomeraseGO:003221150.015
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.015
negative regulation of cellular catabolic processGO:0031330830.015
positive regulation of growthGO:0045927580.015
carbohydrate homeostasisGO:0033500310.015
regulation of gene expression epigeneticGO:0040029730.015
immune effector processGO:00022521590.015
response to inorganic substanceGO:00100351270.015
mitotic g2 dna damage checkpointGO:000709570.014
response to nitrogen compoundGO:19016981840.014
negative regulation of telomerase activityGO:005197460.014
leukocyte proliferationGO:0070661740.014
Mouse
positive regulation of apoptotic processGO:00430652460.014
regulation of lymphocyte activationGO:00512491030.014
Mouse
regulation of protein maturationGO:19033171500.014
chromosome condensationGO:0030261150.014
positive regulation of homeostatic processGO:0032846470.014
g1 s transition of mitotic cell cycleGO:0000082780.014
cell activation involved in immune responseGO:0002263300.014
negative regulation of protein metabolic processGO:00512483910.014
regulation of cytoplasmic transportGO:19036491490.014
resolution of meiotic recombination intermediatesGO:000071230.014
negative regulation of cellular protein catabolic processGO:1903363380.013
regulation of nuclease activityGO:0032069110.013
cell activationGO:00017752130.013
Mouse
macromolecule glycosylationGO:0043413630.013
reproductive processGO:00224141060.013
peptidyl threonine phosphorylationGO:0018107410.013
regulation of sister chromatid segregationGO:0033045270.013
histone modificationGO:00165702510.013
regulation of proteolysisGO:00301622930.013
regulation of mitotic sister chromatid segregationGO:0033047270.013
dna packagingGO:0006323770.013
regulation of kinase activityGO:00435493140.013
dna strand elongation involved in dna replicationGO:000627130.013
negative regulation of phosphate metabolic processGO:00459362670.013
regulation of peptidyl lysine acetylationGO:2000756220.012
cell morphogenesisGO:00009022960.012
cardiovascular system developmentGO:00723582620.012
negative regulation of mitosisGO:0045839240.012
brain developmentGO:0007420970.012
system processGO:00030083490.012
microtubule organizing center organizationGO:0031023620.012
cellular response to oxygen containing compoundGO:19017012760.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of nucleocytoplasmic transportGO:0046822980.011
cellular lipid metabolic processGO:00442553030.011
regulation of meiotic cell cycleGO:005144540.011
neural crest cell migrationGO:000175520.011
neurogenesisGO:00220081690.011
nucleosome assemblyGO:0006334500.011
protein dephosphorylationGO:0006470810.011
cellular component morphogenesisGO:00329893140.011
negative regulation of protein processingGO:00109551420.011
regulation of helicase activityGO:005109580.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
isotype switchingGO:004519030.011
glycosylationGO:0070085710.011
response to activityGO:001482300.011
secretion by cellGO:00329402260.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
positive regulation of mapk cascadeGO:00434101900.011
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238150.010
single organism carbohydrate metabolic processGO:00447231930.010
regulation of mitotic recombinationGO:000001910.010
Mouse
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.010
cellular homeostasisGO:00197251960.010
translesion synthesisGO:001998580.010
cellular response to cytokine stimulusGO:00713451810.010
regulation of microtubule cytoskeleton organizationGO:0070507610.010
actin filament based processGO:00300292240.010

BLM disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.973
hematopoietic system diseaseDOID:741000.929
bone marrow diseaseDOID:4961310.929
disease of cellular proliferationDOID:145661740.766
thoracic cancerDOID:5093210.621
cancerDOID:1621670.621
organ system cancerDOID:00506861640.621
breast cancerDOID:1612210.621
anemiaDOID:2355550.351
aplastic anemiaDOID:12449300.351
congenital hypoplastic anemiaDOID:1342260.299
fanconi s anemiaDOID:13636160.299
endocrine gland cancerDOID:170260.046
pancreatic cancerDOID:179380.046
reproductive organ cancerDOID:193230.014