Homo sapiens

0 known processes

ABCG4

ATP-binding cassette, sub-family G (WHITE), member 4

(Aliases: WHITE2)

ABCG4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203380.433
cation transmembrane transportGO:00986552380.395
g protein coupled receptor signaling pathwayGO:00071862070.385
cation transportGO:00068123310.350
inorganic cation transmembrane transportGO:00986621940.291
transmembrane transportGO:00550853990.279
Human
metal ion transportGO:00300012720.275
inorganic ion transmembrane transportGO:00986602310.205
chemical homeostasisGO:00488783060.182
Human
ion homeostasisGO:00508012300.182
Human
regulation of ion transportGO:00432691890.139
system processGO:00030083490.131
positive regulation of transportGO:00510503360.124
Mouse
locomotory behaviorGO:000762610.123
cellular amino acid metabolic processGO:00065201160.114
regulation of secretionGO:00510461940.111
cell cell signalingGO:00072671550.109
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.105
regulation of ion transmembrane transportGO:00347651320.105
hindbrain developmentGO:003090230.098
regulation of locomotionGO:00400123290.096
regulation of secretion by cellGO:19035301770.096
regulation of cellular amino acid metabolic processGO:000652160.089
cellular chemical homeostasisGO:00550821800.088
regulation of transmembrane transportGO:00347621390.086
positive regulation of developmental processGO:00510943140.086
nervous system developmentGO:00073992930.085
cation homeostasisGO:00550801890.085
matingGO:000761810.080
behaviorGO:00076101120.080
positive regulation of cellular amino acid metabolic processGO:004576430.078
positive regulation of phosphorylationGO:00423273940.076
post embryonic developmentGO:000979120.074
regulation of cellular amine metabolic processGO:0033238110.072
response to oxygen containing compoundGO:19017003690.072
positive regulation of mapk cascadeGO:00434101900.070
regulation of cellular ketone metabolic processGO:0010565500.069
cellular amine metabolic processGO:0044106410.068
response to lipidGO:00339932060.067
Human
organ formationGO:004864530.066
generation of neuronsGO:00486991520.064
associative learningGO:000830610.064
cellular ketone metabolic processGO:0042180800.064
regulation of cell differentiationGO:00455953930.064
secretion by cellGO:00329402260.063
cellular ion homeostasisGO:00068731680.062
divalent metal ion transportGO:00708381520.060
cellular cation homeostasisGO:00300031630.059
positive regulation of cellular amine metabolic processGO:003324070.059
nitrogen compound transportGO:00717051910.057
regulation of synaptic plasticityGO:004816730.057
regulation of cell developmentGO:00602841610.055
metencephalon developmentGO:002203720.055
secretionGO:00469032540.055
regulation of metal ion transportGO:00109591200.055
metal ion homeostasisGO:00550651690.054
mapk cascadeGO:00001652880.054
positive regulation of cell differentiationGO:00455972110.052
regulation of cellular component movementGO:00512703340.052
anion transportGO:00068201610.052
Human
cell developmentGO:00484683280.051
purine ribonucleoside triphosphate metabolic processGO:00092054110.051
Human
negative regulation of multicellular organismal processGO:00512413170.051
cell morphogenesisGO:00009022960.050
purine nucleoside triphosphate metabolic processGO:00091444120.050
Human
cellular component morphogenesisGO:00329893140.050
regulation of cell motilityGO:20001452990.049
regulation of nucleotide metabolic processGO:00061402690.049
amine metabolic processGO:0009308440.049
neuron differentiationGO:00301821380.048
purine nucleotide catabolic processGO:00061954050.048
Human
purine ribonucleoside triphosphate catabolic processGO:00092073910.048
Human
regulation of transferase activityGO:00513383550.047
memoryGO:000761330.047
regulation of kinase activityGO:00435493140.047
ribonucleotide catabolic processGO:00092614050.047
Human
neurological system processGO:00508771630.047
calcium ion transportGO:00068161470.046
cell projection organizationGO:00300302520.046
nucleoside catabolic processGO:00091644080.045
Human
positive regulation of cellular component organizationGO:00511303760.045
response to abiotic stimulusGO:00096283360.045
negative regulation of catalytic activityGO:00430863350.044
divalent inorganic cation transportGO:00725111580.044
regulation of purine nucleotide metabolic processGO:19005422640.044
anatomical structure formation involved in morphogenesisGO:00486462840.044
organophosphate catabolic processGO:00464344300.043
Human
cellular response to endogenous stimulusGO:00714953360.043
positive regulation of catabolic processGO:00098963100.043
organic anion transportGO:00157111030.042
Human
purine nucleoside catabolic processGO:00061523980.042
Human
cellular metal ion homeostasisGO:00068751460.041
cellular homeostasisGO:00197251960.041
adult locomotory behaviorGO:000834410.041
neurogenesisGO:00220081690.041
purine ribonucleoside catabolic processGO:00461303980.041
Human
organic hydroxy compound metabolic processGO:19016151470.040
Human Mouse
regulation of protein kinase activityGO:00458592890.040
cytokine productionGO:00018162470.039
potassium ion transmembrane transportGO:0071805600.039
monovalent inorganic cation transportGO:00156721280.039
nucleotide catabolic processGO:00091664080.038
Human
purine containing compound catabolic processGO:00725234110.038
Human
response to organic cyclic compoundGO:00140702040.038
vesicle mediated transportGO:00161923710.038
divalent inorganic cation homeostasisGO:00725071360.038
signal transduction by phosphorylationGO:00230142970.037
regulation of neuron differentiationGO:0045664700.037
purine ribonucleotide catabolic processGO:00091544040.037
Human
oxidation reduction processGO:00551143960.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
Human
nucleoside triphosphate catabolic processGO:00091433940.037
Human
ribonucleoside triphosphate metabolic processGO:00091994120.036
Human
regulation of mapk cascadeGO:00434082620.036
purine ribonucleoside metabolic processGO:00461284370.036
Human
ribonucleoside catabolic processGO:00424544060.036
Human
positive regulation of transferase activityGO:00513472270.036
calcium ion homeostasisGO:00550741220.036
positive regulation of locomotionGO:00400171860.035
regulation of membrane potentialGO:0042391950.035
small gtpase mediated signal transductionGO:0007264780.035
positive regulation of cellular catabolic processGO:00313312840.035
nucleoside phosphate catabolic processGO:19012924120.035
Human
positive regulation of protein kinase activityGO:00458601900.035
negative regulation of cellular protein metabolic processGO:00322693530.034
regulation of nucleoside metabolic processGO:00091182090.034
regulation of cytokine productionGO:00018172320.034
brain developmentGO:0007420970.034
cellular response to oxygen containing compoundGO:19017012760.034
negative regulation of protein metabolic processGO:00512483910.034
central nervous system developmentGO:00074171230.034
regulation of acrosome reactionGO:006004640.034
positive regulation of kinase activityGO:00336742040.034
actin filament based processGO:00300292240.034
regulation of response to external stimulusGO:00321012220.033
positive regulation of protein phosphorylationGO:00019343130.033
reactive oxygen species metabolic processGO:0072593750.033
muscle contractionGO:0006936730.033
regulation of anatomical structure morphogenesisGO:00226032860.033
cytosolic calcium ion homeostasisGO:0051480890.033
protein maturationGO:00516042330.033
regulation of calcium ion transportGO:0051924790.032
multicellular organismal agingGO:001025930.032
cerebellum developmentGO:002154920.032
regulation of cell migrationGO:00303342890.032
protein processingGO:00164852260.032
cellular divalent inorganic cation homeostasisGO:00725031280.032
regulation of protein localizationGO:00328802960.032
circulatory system processGO:00030131130.031
cellular calcium ion homeostasisGO:00068741170.031
female gamete generationGO:000729220.031
regulation of nervous system developmentGO:0051960880.031
cardiovascular system developmentGO:00723582620.031
cardiac muscle cell contractionGO:008600340.030
lipid metabolic processGO:00066293810.030
Human Mouse
determination of adult lifespanGO:000834020.030
cytoplasmic transportGO:00164823790.030
negative regulation of cellular component organizationGO:00511292350.029
positive regulation of cell proliferationGO:00082843010.029
negative regulation of programmed cell deathGO:00430693210.029
reactive oxygen species biosynthetic processGO:190340940.029
neuron projection developmentGO:00311751060.029
potassium ion transportGO:0006813620.029
cell morphogenesis involved in differentiationGO:00009041440.029
nerve developmentGO:002167540.028
positive regulation of nucleotide metabolic processGO:00459812300.028
negative regulation of phosphorus metabolic processGO:00105632670.028
sensory perceptionGO:00076001030.028
regulation of cellular component biogenesisGO:00440872810.028
gtp catabolic processGO:00061842370.028
nucleoside triphosphate metabolic processGO:00091414220.028
Human
guanosine containing compound catabolic processGO:19010692390.028
segmentationGO:003528240.028
protein oligomerizationGO:00512591730.027
negative regulation of cell deathGO:00605483450.027
cellular lipid metabolic processGO:00442553030.027
gtp metabolic processGO:00460392390.027
oogenesisGO:004847720.027
sensory perception of painGO:001923340.027
cellular response to dna damage stimulusGO:00069743790.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
neuromuscular junction developmentGO:000752830.027
neuron developmentGO:00486661130.026
cell adhesionGO:00071553250.026
positive regulation of ion transportGO:0043270870.026
synaptic transmissionGO:0007268610.026
regulation of protein serine threonine kinase activityGO:00719001790.026
purine nucleoside triphosphate catabolic processGO:00091463920.026
Human
cellular potassium ion transportGO:0071804600.026
regulation of neurogenesisGO:0050767820.026
regulation of hormone levelsGO:00108171250.026
positive regulation of protein serine threonine kinase activityGO:00719021190.026
regulation of cellular response to stressGO:00801352440.026
glycosyl compound catabolic processGO:19016584130.026
Human
angiogenesisGO:00015251470.026
regulation of reactive oxygen species biosynthetic processGO:190342630.025
positive regulation of gtp catabolic processGO:00331261660.025
reactive nitrogen species metabolic processGO:200105730.025
growthGO:00400072020.025
vasculature developmentGO:00019441810.025
single organism membrane organizationGO:00448022680.025
small molecule biosynthetic processGO:00442831570.025
Mouse
regulation of purine nucleotide catabolic processGO:00331212050.025
positive regulation of cell developmentGO:0010720920.025
regulation of cell cycleGO:00517263930.025
motor neuron axon guidanceGO:000804520.025
organ morphogenesisGO:00098871470.025
regulation of establishment of protein localizationGO:00702012420.024
blood vessel developmentGO:00015681720.024
regulation of reactive oxygen species metabolic processGO:2000377410.024
head developmentGO:00603221080.024
cell projection morphogenesisGO:00488581290.024
peripheral nervous system developmentGO:000742220.024
regenerationGO:003109940.024
negative regulation of phosphate metabolic processGO:00459362670.023
positive regulation of hydrolase activityGO:00513453310.023
multicellular organismal response to stressGO:003355510.023
chromatin organizationGO:00063253510.023
chromatin modificationGO:00165682980.023
guanosine containing compound metabolic processGO:19010682440.023
positive regulation of nucleoside metabolic processGO:00459791860.022
regulation of nucleotide catabolic processGO:00308112050.022
biological adhesionGO:00226103310.022
regulation of ion transmembrane transporter activityGO:0032412720.022
positive regulation of cellular component movementGO:00512721810.022
ras protein signal transductionGO:0007265730.022
lipid biosynthetic processGO:00086101770.022
Mouse
action potentialGO:0001508340.022
regulation of cell projection organizationGO:00313441070.021
rho protein signal transductionGO:0007266260.021
morphogenesis of embryonic epitheliumGO:001633140.021
response to external biotic stimulusGO:00432072610.021
taxisGO:00423301570.021
positive regulation of secretionGO:00510471160.021
response to nitrogen compoundGO:19016981840.021
negative regulation of cell proliferationGO:00082852280.021
calcium ion transmembrane transportGO:0070588760.021
circulatory system developmentGO:00723592620.020
negative regulation of protein modification processGO:00314002000.020
regulation of cell morphogenesis involved in differentiationGO:0010769830.020
positive regulation of nucleotide catabolic processGO:00308131850.020
anion transmembrane transportGO:0098656760.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
regulation of neuron projection developmentGO:0010975570.020
mitotic cell cycle processGO:19030472860.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
cell growthGO:00160491600.020
limbic system developmentGO:002176130.020
mitotic cell cycleGO:00002783260.020
positive regulation of cytosolic calcium ion concentrationGO:0007204820.019
blood circulationGO:00080151130.019
epithelial cell migrationGO:00106311190.019
regulation of proteolysisGO:00301622930.019
regulation of map kinase activityGO:00434051080.019
single organism cellular localizationGO:19025803320.019
negative regulation of hydrolase activityGO:00513461820.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
organonitrogen compound biosynthetic processGO:19015662000.019
positive regulation of cytokine productionGO:00018191670.019
sodium ion transmembrane transportGO:0035725590.019
membrane organizationGO:00610242920.019
negative regulation of cellular amine metabolic processGO:003323930.019
histone modificationGO:00165702510.019
activation of protein kinase activityGO:0032147900.019
innate immune responseGO:00450871780.018
regulation of system processGO:00440571010.018
regulation of cell growthGO:00015581350.018
negative regulation of apoptotic processGO:00430663160.018
positive regulation of cell motilityGO:20001471770.018
negative regulation of intracellular signal transductionGO:19025321830.018
immune responseGO:00069553070.018
regulation of homeostatic processGO:00328441210.018
visual behaviorGO:000763220.018
negative regulation of developmental processGO:00510932470.018
detection of stimulusGO:0051606850.018
defense responseGO:00069523150.018
dna repairGO:00062811980.018
multicellular organismal signalingGO:0035637340.017
positive regulation of organelle organizationGO:00106381950.017
blood vessel morphogenesisGO:00485141620.017
cellular macromolecular complex assemblyGO:00346223240.017
visual learningGO:000854210.017
organophosphate biosynthetic processGO:00904071630.017
regulation of transporter activityGO:0032409820.017
regulation of protein secretionGO:0050708860.017
signal releaseGO:0023061700.017
blastoderm segmentationGO:000735020.017
regulation of gtpase activityGO:00430871800.017
protein catabolic processGO:00301633250.017
positive regulation of neurogenesisGO:0050769490.017
startle responseGO:000196430.017
regulation of protein complex assemblyGO:00432541470.017
ameboidal type cell migrationGO:00016671350.017
positive regulation of cell deathGO:00109422630.017
positive regulation of cell cycleGO:00457871400.017
positive regulation of secretion by cellGO:19035321080.017
neurotransmitter secretionGO:000726940.017
positive regulation of gtpase activityGO:00435471660.016
response to other organismGO:00517072610.016
regulation of acetylcholine gated cation channel activityGO:190304810.016
regulation of angiogenesisGO:0045765920.016
activation of mapk activityGO:0000187450.016
positive regulation of nervous system developmentGO:0051962540.016
regulation of actin filament based processGO:00329701410.016
striated muscle contractionGO:0006941520.016
response to hormoneGO:00097251750.016
response to inorganic substanceGO:00100351270.016
cellular response to lipidGO:00713961270.016
response to metal ionGO:0010038840.016
oocyte differentiationGO:000999420.016
apoptotic signaling pathwayGO:00971902680.016
actin filament based movementGO:0030048170.016
regulation of vesicle mediated transportGO:00606271300.016
organic hydroxy compound biosynthetic processGO:1901617710.016
Mouse
cell divisionGO:00513011680.016
chemotaxisGO:00069351570.016
negative regulation of phosphorylationGO:00423261740.016
second messenger mediated signalingGO:0019932780.016
oocyte developmentGO:004859910.016
regulation of gtp catabolic processGO:00331241800.016
regulation of cytoskeleton organizationGO:00514931770.016
covalent chromatin modificationGO:00165692540.016
cranial nerve developmentGO:002154540.016
regulation of vasculature developmentGO:1901342970.016
copulationGO:000762010.015
regulation of neuronal synaptic plasticityGO:004816810.015
tripartite regional subdivisionGO:000735120.015
synaptic transmission involved in micturitionGO:006008420.015
regulation of growthGO:00400081650.015
negative regulation of protein phosphorylationGO:00019331400.015
circadian behaviorGO:004851220.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
cellular protein catabolic processGO:00442572610.015
epithelium migrationGO:00901321190.015
regulation of protein processingGO:00706131500.015
cellular macromolecule catabolic processGO:00442653800.015
regulation of cell cycle processGO:00105642660.015
positive regulation of programmed cell deathGO:00430682490.015
response to light stimulusGO:0009416870.015
inner ear morphogenesisGO:004247240.015
embryonic camera type eye developmentGO:003107620.015
anterior posterior axis specification embryoGO:000859520.015
response to growth factorGO:00708482050.015
positive regulation of neuron differentiationGO:0045666400.015
immune effector processGO:00022521590.015
dephosphorylationGO:00163112090.015
response to oxidative stressGO:00069791210.015
postsynaptic membrane organizationGO:000194120.015
cellular response to cytokine stimulusGO:00713451810.015
positive regulation of apoptotic processGO:00430652460.015
positive regulation of synaptic transmissionGO:005080640.015
hippocampus developmentGO:002176610.015
maintenance of locationGO:00512351120.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
response to radiationGO:00093141510.015
organic hydroxy compound transportGO:0015850630.015
Human Mouse
negative regulation of organelle organizationGO:00106391260.015
alcohol metabolic processGO:00060661140.015
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.015
rhythmic behaviorGO:000762220.014
anterior posterior axis specificationGO:000994820.014
negative regulation of catabolic processGO:00098951040.014
response to biotic stimulusGO:00096072760.014
positive regulation of map kinase activityGO:0043406800.014
regulation of ras gtpase activityGO:00323181280.014
negative regulation of transportGO:00510511760.014
carboxylic acid transportGO:0046942630.014
muscle structure developmentGO:0061061980.014
fatty acid metabolic processGO:00066311150.014
organic acid transportGO:0015849650.014
negative regulation of cell cycleGO:00457861930.014
cell fate determinationGO:000170930.014
negative regulation of synaptic transmissionGO:005080520.014
single organism cell adhesionGO:00986021790.014
microtubule based processGO:00070172100.014
cellular response to organic cyclic compoundGO:00714071270.014
transmission of nerve impulseGO:0019226110.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
cell part morphogenesisGO:00329901370.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
regulation of protein maturationGO:19033171500.014
positive regulation of cellular component biogenesisGO:00440891580.014
negative regulation of transferase activityGO:00513481240.014
actin mediated cell contractionGO:0070252120.014
cellular protein complex assemblyGO:00436231880.013
regulation of multi organism processGO:00439001570.013
positive regulation of angiogenesisGO:0045766510.013
cellular response to growth factor stimulusGO:00713631970.013
protein targetingGO:00066051870.013
microtubule cytoskeleton organizationGO:00002261760.013
membrane hyperpolarizationGO:006008110.013
positive regulation of cell migrationGO:00303351720.013
cell proliferation involved in heart valve developmentGO:200079310.013
embryonic camera type eye morphogenesisGO:004859620.013
protein modification by small protein conjugationGO:00324463420.013
forebrain generation of neuronsGO:002187230.013
reproductive processGO:00224141060.013
response to organonitrogen compoundGO:00102431560.013
negative regulation of protein maturationGO:19033181420.013
regulation of protein transportGO:00512232130.013
stem cell divisionGO:001714520.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
serotonin transportGO:000683730.013
positive regulation of calcium ion transportGO:0051928510.013
regulation of behaviorGO:0050795820.013
protein ubiquitinationGO:00165673140.013
protein localization to organelleGO:00333652800.013
positive regulation of cell projection organizationGO:0031346640.013
small molecule catabolic processGO:0044282920.013
response to nutrient levelsGO:0031667810.013
carbohydrate metabolic processGO:00059752070.013
tissue migrationGO:00901301190.012
response to decreased oxygen levelsGO:0036293960.012
epithelium developmentGO:00604292270.012
positive regulation of immune system processGO:00026842830.012
intracellular protein transportGO:00068862700.012
peptidyl serine modificationGO:00182091060.012
tissue regenerationGO:004224630.012
epithelial cell proliferationGO:00506731280.012
regulation of dna metabolic processGO:00510521530.012
regulation of meiotic cell cycleGO:005144540.012
regulation of cell morphogenesisGO:00226041530.012
response to axon injuryGO:004867810.012
peptidyl tyrosine phosphorylationGO:00181081700.012
negative regulation of protein processingGO:00109551420.012
multi organism cellular processGO:00447641560.012
response to virusGO:00096151260.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
response to oxygen levelsGO:00704821000.012
negative regulation of proteolysisGO:00458611320.012
posttranscriptional regulation of gene expressionGO:00106082130.012
epidermis morphogenesisGO:004873030.012
micturitionGO:006007330.012
monocarboxylic acid metabolic processGO:00327871850.012
glial cell migrationGO:000834740.012
regulation of intracellular transportGO:00323861950.012
cytokine secretionGO:0050663640.012
synaptic transmission cholinergicGO:000727120.012
protein secretionGO:0009306980.012
actin cytoskeleton organizationGO:00300362070.012
regulation of mitotic cell cycleGO:00073461890.012
embryonic eye morphogenesisGO:004804820.012
regulation of ras protein signal transductionGO:00465781550.012
regulation of apoptotic signaling pathwayGO:20012331750.012
negative regulation of cytokine productionGO:0001818820.012
muscle system processGO:0003012810.012
i kappab kinase nf kappab signalingGO:00072491660.011
sleepGO:003043120.011
cell morphogenesis involved in neuron differentiationGO:0048667440.011
regulation of endopeptidase activityGO:00525481700.011
endocytosisGO:00068971590.011
regulation of transmembrane transporter activityGO:0022898740.011
endothelial cell migrationGO:0043542860.011
neuropeptide signaling pathwayGO:0007218190.011
positive regulation of epithelial cell proliferationGO:0050679650.011
regulation of protein catabolic processGO:00421761550.011
axon regenerationGO:003110310.011
sequestering of metal ionGO:0051238240.011
response to extracellular stimulusGO:0009991850.011
regulation of meiosisGO:004002030.011
lipid modificationGO:0030258840.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
sequestering of calcium ionGO:0051208170.011
lipid localizationGO:00108761060.011
Human Mouse
opioid receptor signaling pathwayGO:003800340.011
organelle assemblyGO:00709251760.011
cellular response to hormone stimulusGO:00328701250.011
protein autophosphorylationGO:00467771230.011
inorganic anion transportGO:0015698600.011
lipid catabolic processGO:0016042840.011
spermatid differentiationGO:004851540.011
cellular response to glucocorticoid stimulusGO:007138540.011
cellular response to abiotic stimulusGO:00712141170.011
establishment of protein localization to organelleGO:00725941720.011
blastocyst developmentGO:000182430.011
peptidyl serine phosphorylationGO:00181051010.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
response to woundingGO:00096111680.011
modification dependent macromolecule catabolic processGO:00436322120.011

ABCG4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.028
sensory system diseaseDOID:00501552030.028
central nervous system diseaseDOID:3311860.021
disease of metabolismDOID:00146672950.018
cancerDOID:1621670.016
organ system cancerDOID:00506861640.016
disease of cellular proliferationDOID:145661740.016
eye and adnexa diseaseDOID:14921500.014
inherited metabolic disorderDOID:6552420.013
eye diseaseDOID:56141490.013
auditory system diseaseDOID:2742530.012
neurodegenerative diseaseDOID:12891020.012
musculoskeletal system diseaseDOID:172230.012