Homo sapiens

0 known processes

HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

(Aliases: MGC90332,HMGCS)

HMGCS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
steroid metabolic processGO:0008202940.997
small molecule biosynthetic processGO:00442831570.988
alcohol metabolic processGO:00060661140.987
lipid biosynthetic processGO:00086101770.979
lipid metabolic processGO:00066293810.979
sterol metabolic processGO:0016125280.967
organic hydroxy compound metabolic processGO:19016151470.926
sterol biosynthetic processGO:0016126100.919
steroid biosynthetic processGO:0006694460.893
monocarboxylic acid biosynthetic processGO:0072330670.892
organic hydroxy compound biosynthetic processGO:1901617710.859
alcohol biosynthetic processGO:0046165520.845
cellular lipid metabolic processGO:00442553030.792
cholesterol metabolic processGO:0008203280.729
associative learningGO:000830610.447
visual behaviorGO:000763220.362
acylglycerol metabolic processGO:0006639270.342
response to phenylpropanoidGO:008018410.308
carboxylic acid biosynthetic processGO:0046394970.276
fatty acid biosynthetic processGO:0006633460.263
inner ear morphogenesisGO:004247240.263
organophosphate biosynthetic processGO:00904071630.238
triglyceride metabolic processGO:0006641230.207
regulation of vesicle mediated transportGO:00606271300.202
response to light stimulusGO:0009416870.195
Rat
negative regulation of phosphate metabolic processGO:00459362670.172
terpenoid metabolic processGO:0006721270.168
amine metabolic processGO:0009308440.161
cellular ketone body metabolic processGO:004695030.159
negative regulation of protein metabolic processGO:00512483910.155
vesicle mediated transportGO:00161923710.150
regulation of protein kinase activityGO:00458592890.144
response to abiotic stimulusGO:00096283360.144
Rat
phospholipid catabolic processGO:0009395120.135
fatty acid elongation polyunsaturated fatty acidGO:003462640.129
regulation of cytoplasmic transportGO:19036491490.128
cholesterol biosynthetic processGO:0006695100.123
regulation of protein serine threonine kinase activityGO:00719001790.123
regulation of transferase activityGO:00513383550.117
post embryonic developmentGO:000979120.117
phosphatidylcholine metabolic processGO:0046470190.106
head developmentGO:00603221080.102
Rat
regulation of cellular ketone metabolic processGO:0010565500.101
negative regulation of lipid metabolic processGO:0045833380.091
single organism membrane buddingGO:1902591100.088
signal transduction by phosphorylationGO:00230142970.086
negative regulation of growth of symbiont in hostGO:004413010.086
glycerolipid metabolic processGO:00464861070.085
positive regulation of cholesterol storageGO:001088640.084
phospholipid metabolic processGO:0006644990.083
intestinal cholesterol absorptionGO:003029940.076
sensory organ morphogenesisGO:0090596210.073
negative regulation of endopeptidase activityGO:0010951840.072
long chain fatty acid biosynthetic processGO:004275940.068
long chain fatty acid metabolic processGO:0001676300.068
ketone body metabolic processGO:190222420.063
sphingolipid metabolic processGO:0006665380.062
phospholipid biosynthetic processGO:0008654440.062
membrane buddingGO:0006900280.059
golgi vesicle transportGO:0048193800.056
terpenoid biosynthetic processGO:001611420.055
regulation of cellular amino acid metabolic processGO:000652160.053
monocarboxylic acid metabolic processGO:00327871850.052
negative regulation of catalytic activityGO:00430863350.051
phosphatidylcholine catabolic processGO:003463830.050
cellular alcohol metabolic processGO:004410770.048
srebp signaling pathwayGO:003293340.045
cholesterol transportGO:0030301390.044
growthGO:00400072020.044
response to lipidGO:00339932060.043
Rat
phospholipid transportGO:0015914230.042
response to radiationGO:00093141510.041
Rat
cellular amine metabolic processGO:0044106410.040
fatty acid metabolic processGO:00066311150.040
regulation of mapk cascadeGO:00434082620.040
regulation of kinase activityGO:00435493140.039
single organism cellular localizationGO:19025803320.037
negative regulation of cellular protein metabolic processGO:00322693530.036
multicellular organismal agingGO:001025930.036
response to sterol depletionGO:000699140.034
male genitalia developmentGO:003053910.033
fatty acid elongation monounsaturated fatty acidGO:003462530.033
acetylcholine transportGO:001587010.033
innate immune responseGO:00450871780.032
cellular biogenic amine metabolic processGO:0006576340.031
maintenance of locationGO:00512351120.031
cellular ketone metabolic processGO:0042180800.031
neutral lipid metabolic processGO:0006638270.029
regulation of cellular amine metabolic processGO:0033238110.029
cellular protein complex assemblyGO:00436231880.029
isoprenoid biosynthetic processGO:000829990.028
negative regulation of protein processingGO:00109551420.028
cellular amino acid metabolic processGO:00065201160.028
determination of adult lifespanGO:000834020.027
female gamete generationGO:000729220.026
negative regulation of kinase activityGO:00336731060.026
fat cell differentiationGO:0045444320.025
cellular response to sterol depletionGO:007150140.025
positive regulation of triglyceride biosynthetic processGO:001086740.025
membrane organizationGO:00610242920.024
negative regulation of protein phosphorylationGO:00019331400.024
visual learningGO:000854210.024
regulation of intracellular transportGO:00323861950.024
neuromuscular junction developmentGO:000752830.023
negative regulation of multi organism processGO:0043901920.023
cognitionGO:0050890430.023
small molecule catabolic processGO:0044282920.023
regulation of er to golgi vesicle mediated transportGO:006062850.023
lipid catabolic processGO:0016042840.023
organophosphate catabolic processGO:00464344300.023
mapk cascadeGO:00001652880.023
oogenesisGO:004847720.023
response to external biotic stimulusGO:00432072610.022
isoprenoid metabolic processGO:0006720390.022
vesicle organizationGO:0016050620.022
system processGO:00030083490.021
multicellular organismal response to stressGO:003355510.020
defense responseGO:00069523150.020
response to biotic stimulusGO:00096072760.020
ras protein signal transductionGO:0007265730.020
mitotic cell cycle processGO:19030472860.020
negative regulation of transferase activityGO:00513481240.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
negative regulation of intracellular signal transductionGO:19025321830.019
lipid storageGO:0019915280.019
negative regulation of protein complex assemblyGO:0031333430.019
response to organic cyclic compoundGO:00140702040.018
Rat
sterol transportGO:0015918390.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
cytoplasmic transportGO:00164823790.018
skin developmentGO:0043588760.018
cellular macromolecule catabolic processGO:00442653800.017
long chain fatty acid importGO:004453950.017
bone morphogenesisGO:0060349100.017
regulation of cellular component biogenesisGO:00440872810.017
regulation of lipid metabolic processGO:0019216960.017
er nucleus signaling pathwayGO:0006984230.017
regulation of proteolysisGO:00301622930.017
immune system developmentGO:00025201950.017
anterior posterior axis specificationGO:000994820.017
icosanoid secretionGO:0032309110.017
endocytosisGO:00068971590.016
locomotory behaviorGO:000762610.016
dephosphorylationGO:00163112090.016
rho protein signal transductionGO:0007266260.016
response to fungusGO:000962040.016
mitotic cell cycleGO:00002783260.016
negative regulation of protein modification processGO:00314002000.016
negative regulation of hydrolase activityGO:00513461820.016
positive regulation of nucleoside metabolic processGO:00459791860.016
purine containing compound catabolic processGO:00725234110.016
chemical homeostasisGO:00488783060.016
regulation of map kinase activityGO:00434051080.016
regulation of nucleotide metabolic processGO:00061402690.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
cellular macromolecular complex assemblyGO:00346223240.016
regulation of synaptic plasticityGO:004816730.016
negative regulation of phosphorus metabolic processGO:00105632670.015
protein processingGO:00164852260.015
negative regulation of growth of symbiont involved in interaction with hostGO:004414620.015
immune responseGO:00069553070.015
negative regulation of proteolysisGO:00458611320.015
positive regulation of cellular component organizationGO:00511303760.015
neurotransmitter secretionGO:000726940.015
response to nutrientGO:0007584200.014
Rat
morphogenesis of embryonic epitheliumGO:001633140.014
photoreceptor cell differentiationGO:004653020.014
blastoderm segmentationGO:000735020.014
cholesterol importGO:007050840.014
cardiovascular system developmentGO:00723582620.014
positive regulation of nucleotide metabolic processGO:00459812300.014
regulation of response to external stimulusGO:00321012220.014
ear morphogenesisGO:004247170.014
regulation of cell cycleGO:00517263930.014
peripheral nervous system developmentGO:000742220.014
lipid localizationGO:00108761060.014
cardiac muscle cell contractionGO:008600340.014
negative regulation of protein serine threonine kinase activityGO:0071901570.014
transmembrane transportGO:00550853990.014
negative regulation of cellular amine metabolic processGO:003323930.014
regulation of cell differentiationGO:00455953930.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
response to oxygen levelsGO:00704821000.014
negative regulation of map kinase activityGO:0043407270.014
negative regulation of phosphorylationGO:00423261740.014
actin filament based processGO:00300292240.014
protein oligomerizationGO:00512591730.014
protein localization to membraneGO:00726571600.014
regulation of protein localization to plasma membraneGO:1903076400.014
regulation of cell motilityGO:20001452990.014
regulation of protein localizationGO:00328802960.014
glycosyl compound catabolic processGO:19016584130.014
cell fate determinationGO:000170930.014
cellular alcohol biosynthetic processGO:004410870.013
anion transportGO:00068201610.013
protein catabolic processGO:00301633250.013
regulation of cytokine productionGO:00018172320.013
positive regulation of secretionGO:00510471160.013
embryonic organ morphogenesisGO:0048562240.013
negative regulation of protein kinase activityGO:0006469980.013
spermatid differentiationGO:004851540.013
circulatory system developmentGO:00723592620.013
nerve developmentGO:002167540.013
negative regulation of developmental processGO:00510932470.013
memoryGO:000761330.013
positive regulation of cellular amine metabolic processGO:003324070.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
intracellular protein transportGO:00068862700.013
hindbrain developmentGO:003090230.013
brain developmentGO:0007420970.013
Rat
regulation of growth of symbiont in hostGO:004412610.013
atp metabolic processGO:00460341760.013
negative regulation of cytoplasmic transportGO:1903650460.012
purine ribonucleoside metabolic processGO:00461284370.012
nucleoside triphosphate metabolic processGO:00091414220.012
purine ribonucleoside triphosphate catabolic processGO:00092073910.012
positive regulation of catabolic processGO:00098963100.012
regulation of nucleoside metabolic processGO:00091182090.012
purine ribonucleoside catabolic processGO:00461303980.012
fatty acid elongation saturated fatty acidGO:001936750.012
oocyte developmentGO:004859910.012
negative regulation of programmed cell deathGO:00430693210.012
positive regulation of intracellular transportGO:00323881040.012
ion homeostasisGO:00508012300.012
segmentationGO:003528240.012
regulation of steroid biosynthetic processGO:0050810230.012
regulation of establishment of protein localizationGO:00702012420.012
ribonucleoside triphosphate catabolic processGO:00092033910.012
regulation of protein complex assemblyGO:00432541470.012
spinal cord developmentGO:002151040.012
endomembrane system organizationGO:00102561960.012
organonitrogen compound biosynthetic processGO:19015662000.012
cation transmembrane transportGO:00986552380.012
regulation of immune responseGO:00507762010.012
response to other organismGO:00517072610.012
regulation of purine nucleotide catabolic processGO:00331212050.012
cation homeostasisGO:00550801890.012
response to axon injuryGO:004867810.012
positive regulation of cytoplasmic transportGO:1903651820.012
rhythmic behaviorGO:000762220.012
interspecies interaction between organismsGO:00444191560.012
growth involved in symbiotic interactionGO:004411020.012
apoptotic signaling pathwayGO:00971902680.011
negative regulation of organelle organizationGO:00106391260.011
matingGO:000761810.011
regulation of protein maturationGO:19033171500.011
positive regulation of nucleotide catabolic processGO:00308131850.011
limbic system developmentGO:002176130.011
embryo developmentGO:00097901230.011
positive regulation of transportGO:00510503360.011
purine nucleotide catabolic processGO:00061954050.011
negative regulation of cellular component organizationGO:00511292350.011
calcium ion homeostasisGO:00550741220.011
fatty acyl coa metabolic processGO:003533790.011
establishment of protein localization to organelleGO:00725941720.011
lipoprotein metabolic processGO:0042157420.011
actin mediated cell contractionGO:0070252120.011
cell growthGO:00160491600.011
negative regulation of protein maturationGO:19033181420.011
adult locomotory behaviorGO:000834410.011
nucleoside phosphate catabolic processGO:19012924120.011
nucleocytoplasmic transportGO:00069131760.011
er to golgi vesicle mediated transportGO:0006888190.011
negative regulation of intracellular transportGO:0032387600.011
response to cytokineGO:00340972320.011
fatty acid elongation unsaturated fatty acidGO:001936850.011
ribonucleotide catabolic processGO:00092614050.011
demethylationGO:0070988370.011
positive regulation of organelle organizationGO:00106381950.011
positive regulation of immune system processGO:00026842830.011
purine nucleoside triphosphate metabolic processGO:00091444120.011
nucleotide catabolic processGO:00091664080.011
cellular response to cytokine stimulusGO:00713451810.011
vasculature developmentGO:00019441810.011
secretionGO:00469032540.011
sensory perception of smellGO:000760820.011
cholesterol homeostasisGO:0042632280.010
diterpenoid metabolic processGO:0016101200.010
cellular response to dna damage stimulusGO:00069743790.010
small gtpase mediated signal transductionGO:0007264780.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
positive regulation of hydrolase activityGO:00513453310.010
regulation of purine nucleotide metabolic processGO:19005422640.010
embryonic morphogenesisGO:0048598850.010
regulation of peptidase activityGO:00525471800.010
acetyl coa metabolic processGO:000608480.010
motor neuron axon guidanceGO:000804520.010
oxidation reduction processGO:00551143960.010
lipid transportGO:0006869900.010
regenerationGO:003109940.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
purine ribonucleotide catabolic processGO:00091544040.010
oocyte differentiationGO:000999420.010
hippocampus developmentGO:002176610.010
protein maturationGO:00516042330.010
ribonucleoside catabolic processGO:00424544060.010
copii coated vesicle buddingGO:009011450.010
cell divisionGO:00513011680.010
positive regulation of phosphorylationGO:00423273940.010
single organism membrane organizationGO:00448022680.010
positive regulation of programmed cell deathGO:00430682490.010
neurological system processGO:00508771630.010

HMGCS1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
lipid metabolism disorderDOID:3146260.048
disease of metabolismDOID:00146672950.048
inherited metabolic disorderDOID:6552420.048
musculoskeletal system diseaseDOID:172230.019
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.018
disease of cellular proliferationDOID:145661740.014
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
myopathyDOID:4231040.014
cancerDOID:1621670.013
immune system diseaseDOID:29141550.012
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
retinal degenerationDOID:8466890.011
retinal diseaseDOID:56791180.011