Homo sapiens

0 known processes

HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

HMGCS2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monocarboxylic acid metabolic processGO:00327871850.756
lipid metabolic processGO:00066293810.610
cellular lipid metabolic processGO:00442553030.486
fatty acid metabolic processGO:00066311150.393
response to organic cyclic compoundGO:00140702040.326
Rat
regulation of hormone levelsGO:00108171250.324
oxidation reduction processGO:00551143960.317
vitamin k catabolic processGO:004237720.254
cellular ketone metabolic processGO:0042180800.253
cellular amino acid metabolic processGO:00065201160.226
anion transportGO:00068201610.220
organic anion transportGO:00157111030.213
fatty acid omega oxidationGO:001043020.208
response to oxygen containing compoundGO:19017003690.198
Rat
carboxylic acid biosynthetic processGO:0046394970.187
steroid metabolic processGO:0008202940.187
small molecule biosynthetic processGO:00442831570.186
Rat
response to hormoneGO:00097251750.158
Rat
phylloquinone metabolic processGO:004237420.148
cellular amine metabolic processGO:0044106410.141
chemical homeostasisGO:00488783060.136
9 cis retinoic acid biosynthetic processGO:004290410.135
amine metabolic processGO:0009308440.133
cation transportGO:00068123310.128
leukotriene b4 metabolic processGO:003610220.127
system processGO:00030083490.125
sulfur compound metabolic processGO:00067901010.124
negative regulation of icosanoid secretionGO:003230420.124
organic hydroxy compound metabolic processGO:19016151470.124
organic acid biosynthetic processGO:0016053970.115
lipid biosynthetic processGO:00086101770.115
epoxygenase p450 pathwayGO:001937330.114
alcohol metabolic processGO:00060661140.111
isoquinoline alkaloid metabolic processGO:003307610.111
regulation of cellular amine metabolic processGO:0033238110.105
regulation of cellular ketone metabolic processGO:0010565500.105
icosanoid catabolic processGO:190152320.104
response to lipidGO:00339932060.104
Rat
cellular response to oxygen containing compoundGO:19017012760.104
Rat
response to xenobiotic stimulusGO:0009410300.100
negative regulation of cell deathGO:00605483450.099
secretionGO:00469032540.089
monocarboxylic acid biosynthetic processGO:0072330670.088
quinone catabolic processGO:190166220.088
response to nitrogen compoundGO:19016981840.088
Rat
response to inorganic substanceGO:00100351270.085
Rat
response to metal ionGO:0010038840.084
Rat
cellular response to endogenous stimulusGO:00714953360.084
Rat
menaquinone metabolic processGO:000923330.083
post embryonic developmentGO:000979120.082
cellular response to xenobiotic stimulusGO:0071466290.080
single organism carbohydrate metabolic processGO:00447231930.079
metal ion homeostasisGO:00550651690.076
cellular response to genisteinGO:007141210.076
positive regulation of phosphorylationGO:00423273940.076
hormone metabolic processGO:0042445610.075
ion homeostasisGO:00508012300.074
alkaloid metabolic processGO:000982040.073
long chain fatty acid metabolic processGO:0001676300.071
cellular modified amino acid metabolic processGO:0006575640.070
protein processingGO:00164852260.069
carboxylic acid transportGO:0046942630.068
lipid catabolic processGO:0016042840.067
carbohydrate metabolic processGO:00059752070.066
vitamin k biosynthetic processGO:004237120.066
regulation of cellular component movementGO:00512703340.065
positive regulation of transportGO:00510503360.064
nitrogen compound transportGO:00717051910.063
drug catabolic processGO:0042737100.061
transmembrane transportGO:00550853990.059
biological adhesionGO:00226103310.059
negative regulation of catalytic activityGO:00430863350.059
menaquinone catabolic processGO:004236120.058
regulation of cellular amino acid metabolic processGO:000652160.057
protein maturationGO:00516042330.056
negative regulation of apoptotic processGO:00430663160.055
retinoic acid biosynthetic processGO:000213820.054
regulation of body fluid levelsGO:0050878990.053
negative regulation of protein metabolic processGO:00512483910.053
terpenoid metabolic processGO:0006721270.053
phylloquinone catabolic processGO:004237620.052
positive regulation of protein phosphorylationGO:00019343130.052
response to organonitrogen compoundGO:00102431560.052
Rat
diterpenoid metabolic processGO:0016101200.052
coumarin metabolic processGO:000980420.052
leukotriene b4 catabolic processGO:003610120.050
leukotriene catabolic processGO:003610020.049
response to other organismGO:00517072610.048
Rat
fatty acid derivative metabolic processGO:1901568350.047
isoprenoid metabolic processGO:0006720390.047
ion transmembrane transportGO:00342203380.046
negative regulation of programmed cell deathGO:00430693210.046
regulation of proteolysisGO:00301622930.046
regulation of kinase activityGO:00435493140.045
regulation of locomotionGO:00400123290.045
immune response in mucosal associated lymphoid tissueGO:000238610.045
vitamin e metabolic processGO:004236010.045
regulation of secretionGO:00510461940.045
cellular lipid catabolic processGO:0044242650.044
unsaturated fatty acid metabolic processGO:0033559370.044
growthGO:00400072020.043
cellular homeostasisGO:00197251960.043
organonitrogen compound biosynthetic processGO:19015662000.043
negative regulation of transportGO:00510511760.043
cation homeostasisGO:00550801890.042
metal ion transportGO:00300012720.042
icosanoid metabolic processGO:0006690350.041
coenzyme metabolic processGO:0006732650.040
regulation of protein processingGO:00706131500.040
positive regulation of immune system processGO:00026842830.040
enzyme linked receptor protein signaling pathwayGO:00071673030.040
positive regulation of cellular amine metabolic processGO:003324070.040
response to abiotic stimulusGO:00096283360.040
Rat
positive regulation of cellular amino acid metabolic processGO:004576430.040
defense responseGO:00069523150.040
regulation of protein maturationGO:19033171500.039
multicellular organismal agingGO:001025930.039
lipid modificationGO:0030258840.039
regenerationGO:003109940.039
cellular chemical homeostasisGO:00550821800.038
response to biotic stimulusGO:00096072760.038
Rat
lipid transportGO:0006869900.038
regulation of response to woundingGO:19030341010.038
cell growthGO:00160491600.037
negative regulation of cellular protein metabolic processGO:00322693530.037
carboxylic acid catabolic processGO:0046395710.037
regulation of response to external stimulusGO:00321012220.037
small molecule catabolic processGO:0044282920.037
apoptotic signaling pathwayGO:00971902680.036
negative regulation of protein processingGO:00109551420.035
regulation of cell motilityGO:20001452990.035
xenobiotic metabolic processGO:0006805280.035
positive regulation of developmental processGO:00510943140.034
regulation of transferase activityGO:00513383550.034
naphthalene metabolic processGO:001893110.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
cofactor metabolic processGO:0051186870.033
drug metabolic processGO:0017144190.033
regulation of anatomical structure morphogenesisGO:00226032860.033
epithelial cell differentiationGO:00308551410.033
response to drugGO:0042493810.033
Rat
coagulationGO:0050817780.033
secretion by cellGO:00329402260.033
negative regulation of protein maturationGO:19033181420.032
mapk cascadeGO:00001652880.032
nucleoside catabolic processGO:00091644080.032
wound healingGO:00420601150.032
regulation of cell differentiationGO:00455953930.032
maintenance of locationGO:00512351120.032
segmentationGO:003528240.032
lipid localizationGO:00108761060.032
organic acid transportGO:0015849650.032
epithelium developmentGO:00604292270.031
cellular cation homeostasisGO:00300031630.031
determination of adult lifespanGO:000834020.031
signal transduction by phosphorylationGO:00230142970.031
organic hydroxy compound transportGO:0015850630.031
blood circulationGO:00080151130.031
linoleic acid metabolic processGO:004365140.031
cellular response to hormone stimulusGO:00328701250.031
Rat
regulation of growthGO:00400081650.031
negative regulation of proteolysisGO:00458611320.031
9 cis retinoic acid metabolic processGO:004290510.031
response to external biotic stimulusGO:00432072610.030
Rat
regulation of wound healingGO:0061041560.030
purine ribonucleoside metabolic processGO:00461284370.030
phenylpropanoid metabolic processGO:000969830.030
organic acid catabolic processGO:0016054710.030
cation transmembrane transportGO:00986552380.029
regulation of protein kinase activityGO:00458592890.029
response to steroid hormoneGO:0048545800.029
Rat
vesicle mediated transportGO:00161923710.029
cell adhesionGO:00071553250.029
organophosphate catabolic processGO:00464344300.029
hormone transportGO:0009914680.029
purine nucleoside catabolic processGO:00061523980.028
renal water homeostasisGO:000309140.028
androgen biosynthetic processGO:000670230.028
response to woundingGO:00096111680.028
purine nucleotide catabolic processGO:00061954050.028
negative regulation of cellular component organizationGO:00511292350.028
regulation of secretion by cellGO:19035301770.028
female gamete generationGO:000729220.027
negative regulation of cellular organofluorine metabolic processGO:009035010.027
negative regulation of hydrolase activityGO:00513461820.027
urea metabolic processGO:001962730.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
regulation of cell migrationGO:00303342890.027
acetate ester metabolic processGO:190061930.027
hemostasisGO:0007599760.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
cellular response to organic cyclic compoundGO:00714071270.027
Rat
regulation of ion transportGO:00432691890.027
cellular ion homeostasisGO:00068731680.027
regulation of phospholipase c activating g protein coupled receptor signaling pathwayGO:190073610.026
negative regulation of phosphate metabolic processGO:00459362670.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
cellular response to hydroxyisoflavoneGO:007141310.026
regulation of cell growthGO:00015581350.026
positive regulation of protein kinase activityGO:00458601900.026
positive regulation of ion transportGO:0043270870.026
locomotory behaviorGO:000762610.026
thyroid hormone transportGO:007032720.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.025
divalent inorganic cation transportGO:00725111580.025
nucleoside triphosphate metabolic processGO:00091414220.025
purine containing compound catabolic processGO:00725234110.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
salivary gland morphogenesisGO:000743540.025
cellular organohalogen metabolic processGO:009034520.025
interspecies interaction between organismsGO:00444191560.025
positive regulation of transferase activityGO:00513472270.025
negative regulation of cellular organohalogen metabolic processGO:009034910.025
positive regulation of organic acid transportGO:003289230.024
response to cytokineGO:00340972320.024
blood coagulationGO:0007596760.024
regulation of reactive oxygen species metabolic processGO:2000377410.024
cytoplasmic transportGO:00164823790.024
ras protein signal transductionGO:0007265730.024
regulation of mapk cascadeGO:00434082620.024
nucleoside triphosphate catabolic processGO:00091433940.024
toxin metabolic processGO:000940440.024
positive regulation of cell proliferationGO:00082843010.024
nucleoside phosphate catabolic processGO:19012924120.024
negative regulation of response to woundingGO:1903035470.024
negative regulation of phosphorus metabolic processGO:00105632670.024
lipid oxidationGO:0034440330.024
glycerolipid metabolic processGO:00464861070.024
protein oligomerizationGO:00512591730.024
cellular divalent inorganic cation homeostasisGO:00725031280.023
naphthalene containing compound metabolic processGO:009042010.023
dephosphorylationGO:00163112090.023
oxidative demethylationGO:0070989110.023
cytokine productionGO:00018162470.023
glycosyl compound catabolic processGO:19016584130.023
positive regulation of kinase activityGO:00336742040.023
response to phenylpropanoidGO:008018410.023
positive regulation of cellular component movementGO:00512721810.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
positive regulation of catabolic processGO:00098963100.023
response to peptideGO:1901652650.023
Rat
immune responseGO:00069553070.023
cellular hormone metabolic processGO:0034754410.022
regulation of cellular response to stressGO:00801352440.022
drinking behaviorGO:004275610.022
cell activationGO:00017752130.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
positive regulation of cellular catabolic processGO:00313312840.022
fatty acid biosynthetic processGO:0006633460.022
ribonucleoside triphosphate metabolic processGO:00091994120.022
ribonucleoside catabolic processGO:00424544060.022
cellular amide metabolic processGO:0043603690.022
regulation of cytokine productionGO:00018172320.022
muscle contractionGO:0006936730.022
reactive oxygen species metabolic processGO:0072593750.022
nucleotide catabolic processGO:00091664080.022
primary alcohol metabolic processGO:0034308170.022
membrane organizationGO:00610242920.022
actin filament based processGO:00300292240.021
memoryGO:000761330.021
pressure natriuresisGO:000309520.021
positive regulation of secretion by cellGO:19035321080.021
purine ribonucleoside monophosphate metabolic processGO:00091671860.021
negative regulation of cell proliferationGO:00082852280.021
negative regulation of developmental processGO:00510932470.021
response to mercury ionGO:004668940.021
positive regulation of cell migrationGO:00303351720.021
regulation of peptidase activityGO:00525471800.021
cellular response to nitrogen compoundGO:19016991440.021
Rat
divalent metal ion transportGO:00708381520.021
signal releaseGO:0023061700.021
monosaccharide metabolic processGO:0005996740.020
positive regulation of secretionGO:00510471160.020
cellular response to organonitrogen compoundGO:00714171240.020
Rat
single organism membrane organizationGO:00448022680.020
circulatory system processGO:00030131130.020
single organism cellular localizationGO:19025803320.020
oogenesisGO:004847720.020
negative regulation of endopeptidase activityGO:0010951840.020
purine ribonucleoside catabolic processGO:00461303980.020
peptidyl tyrosine modificationGO:00182121700.020
response to fungusGO:000962040.020
regulation of protein serine threonine kinase activityGO:00719001790.020
positive regulation of plasminogen activationGO:001075630.020
cell cell signalingGO:00072671550.019
ribonucleotide catabolic processGO:00092614050.019
arachidonic acid metabolic processGO:0019369140.019
tissue regenerationGO:004224630.019
small gtpase mediated signal transductionGO:0007264780.019
response to decreased oxygen levelsGO:0036293960.019
regulation of cell cycleGO:00517263930.019
mitochondrion organizationGO:00070051560.019
regulation of intracellular transportGO:00323861950.019
positive regulation of hydrolase activityGO:00513453310.019
one carbon compound transportGO:001975540.019
negative regulation of phosphorylationGO:00423261740.018
cellular metal ion homeostasisGO:00068751460.018
divalent inorganic cation homeostasisGO:00725071360.018
estrogen catabolic processGO:000671110.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of lipid metabolic processGO:0019216960.018
amide transportGO:0042886760.018
negative regulation of intracellular signal transductionGO:19025321830.018
organic hydroxy compound biosynthetic processGO:1901617710.018
response to oxygen levelsGO:00704821000.018
somitogenesisGO:000175620.018
regulation of system processGO:00440571010.018
atp metabolic processGO:00460341760.018
spermatid differentiationGO:004851540.018
sequestering of calcium ionGO:0051208170.018
prostate gland developmentGO:003085030.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
extrinsic apoptotic signaling pathwayGO:00971911190.018
multi organism cellular processGO:00447641560.017
peptide metabolic processGO:0006518510.017
protein catabolic processGO:00301633250.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
regulation of protein localizationGO:00328802960.017
inner ear morphogenesisGO:004247240.017
positive regulation of apoptotic processGO:00430652460.017
regulation of apoptotic signaling pathwayGO:20012331750.017
cellular response to dna damage stimulusGO:00069743790.017
innate immune responseGO:00450871780.017
blastoderm segmentationGO:000735020.017
sensory perceptionGO:00076001030.017
renal tubular secretionGO:009725410.017
negative regulation of multicellular organismal processGO:00512413170.017
peptide transportGO:0015833740.017
carbohydrate derivative biosynthetic processGO:19011372070.017
nucleoside monophosphate metabolic processGO:00091231910.017
retinoid metabolic processGO:0001523180.017
calcium ion transportGO:00068161470.017
cellular response to external stimulusGO:00714961110.016
negative regulation of peptidase activityGO:0010466910.016
purine ribonucleotide catabolic processGO:00091544040.016
positive regulation of icosanoid secretionGO:003230530.016
response to activityGO:001482300.016
intracellular protein transportGO:00068862700.016
cardiovascular system developmentGO:00723582620.016
regulation of icosanoid secretionGO:003230340.016
demethylationGO:0070988370.016
neuromuscular junction developmentGO:000752830.016
cellular component morphogenesisGO:00329893140.016
actin filament based movementGO:0030048170.016
positive regulation of programmed cell deathGO:00430682490.016
negative regulation of protein modification processGO:00314002000.016
mitotic cell cycleGO:00002783260.016
chemotaxisGO:00069351570.016
cellular macromolecular complex assemblyGO:00346223240.016
inorganic ion transmembrane transportGO:00986602310.016
acetylcholine metabolic processGO:000829130.016
regulation of cell adhesionGO:00301551660.016
diterpenoid biosynthetic processGO:001610220.016
alpha ketoglutarate transportGO:001574210.016
blood vessel morphogenesisGO:00485141620.016
rna processingGO:00063962550.016
cellular response to lipidGO:00713961270.016
Rat
blood vessel developmentGO:00015681720.015
adult locomotory behaviorGO:000834410.015
long chain fatty acid catabolic processGO:004275830.015
tissue homeostasisGO:0001894630.015
response to bacteriumGO:00096171440.015
Rat
response to nutrient levelsGO:0031667810.015
Rat
neurological system processGO:00508771630.015
spermatid developmentGO:000728640.015
cellular macromolecule catabolic processGO:00442653800.015
nervous system developmentGO:00073992930.015
Rat
response to purine containing compoundGO:0014074400.015
Rat
response to peptide hormoneGO:0043434610.015
Rat
cellular carbohydrate metabolic processGO:0044262840.015
response to oxidative stressGO:00069791210.015
positive regulation of cellular component organizationGO:00511303760.015
endocrine processGO:0050886250.015
phospholipid metabolic processGO:0006644990.015
cellular protein complex assemblyGO:00436231880.015
cell developmentGO:00484683280.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of cell motilityGO:20001471770.015
positive regulation of immune responseGO:00507781590.015
cell substrate adhesionGO:00315891320.015
mitotic cell cycle processGO:19030472860.015
response to acid chemicalGO:0001101660.015
Rat
regulation of hormone secretionGO:0046883570.015
intracellular receptor signaling pathwayGO:00305221040.015
glycerophospholipid metabolic processGO:0006650840.015
hindbrain developmentGO:003090230.015
positive regulation of cell deathGO:00109422630.015
regulation of nucleoside metabolic processGO:00091182090.015
circulatory system developmentGO:00723592620.015
gtp catabolic processGO:00061842370.015
regulation of protein catabolic processGO:00421761550.015
protein modification by small protein conjugationGO:00324463420.015
monocarboxylic acid catabolic processGO:0072329370.015
sequestering of metal ionGO:0051238240.014
fatty acid derivative catabolic processGO:190156920.014
cardiac muscle cell contractionGO:008600340.014
inorganic cation transmembrane transportGO:00986621940.014
response to axon injuryGO:004867810.014
glutathione metabolic processGO:0006749200.014
negative regulation of apoptotic signaling pathwayGO:2001234970.014
nucleoside monophosphate catabolic processGO:00091251590.014
regulation of purine nucleotide catabolic processGO:00331212050.014
cellular calcium ion homeostasisGO:00068741170.014
regulation of glial cell differentiationGO:004568530.014
actin cytoskeleton organizationGO:00300362070.014
response to extracellular stimulusGO:0009991850.014
Rat
chromatin modificationGO:00165682980.014
morphogenesis of embryonic epitheliumGO:001633140.014
reactive oxygen species biosynthetic processGO:190340940.014
sensory perception of chemical stimulusGO:0007606380.014
carnitine transmembrane transportGO:190260330.014
single organism cell adhesionGO:00986021790.014
leukotriene metabolic processGO:0006691100.014
regulation of nucleotide metabolic processGO:00061402690.014
peripheral nervous system developmentGO:000742220.014
negative regulation of transferase activityGO:00513481240.014
peptidyl tyrosine phosphorylationGO:00181081700.014
regulation of homeostatic processGO:00328441210.014
defense response to fungusGO:005083240.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
cellular response to cytokine stimulusGO:00713451810.014
positive regulation of nucleotide metabolic processGO:00459812300.014
posttranscriptional regulation of gene expressionGO:00106082130.014
response to lithium ionGO:001022620.014
alpha amino acid metabolic processGO:1901605720.014
regulation of mitotic cell cycleGO:00073461890.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
behaviorGO:00076101120.013
matingGO:000761810.013
regulation of establishment of protein localizationGO:00702012420.013
negative regulation of gliogenesisGO:001401430.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
actin mediated cell contractionGO:0070252120.013
protein targetingGO:00066051870.013
regulation of cellular organofluorine metabolic processGO:009034810.013
anatomical structure homeostasisGO:00602491000.013
regulation of cell cycle processGO:00105642660.013
hormone secretionGO:0046879650.013
reproductive processGO:00224141060.013
guanosine containing compound catabolic processGO:19010692390.013
astrocyte differentiationGO:004870840.013
nitrogen cycle metabolic processGO:007194130.013
plasma membrane organizationGO:00070091150.013
cellular organofluorine metabolic processGO:009034620.013
response to insulinGO:0032868450.013
Rat
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
neutral lipid catabolic processGO:0046461120.013
regulation of protein transportGO:00512232130.013
regulation of bindingGO:00510981110.013
i kappab kinase nf kappab signalingGO:00072491660.013
phosphatidylinositol mediated signalingGO:0048015550.013
hexose metabolic processGO:0019318550.013
negative regulation of hemostasisGO:1900047220.013
prostate gland morphogenesisGO:006051210.013
negative regulation of blood coagulationGO:0030195220.013
central nervous system developmentGO:00074171230.013
Rat
regulation of anion transportGO:0044070250.013
regulation of erk1 and erk2 cascadeGO:0070372990.013
viral life cycleGO:00190581320.013
alkaloid catabolic processGO:000982230.013
regulation of vesicle mediated transportGO:00606271300.013
anion transmembrane transportGO:0098656760.013
transition metal ion transportGO:0000041230.013
negative regulation of catabolic processGO:00098951040.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
visual behaviorGO:000763220.012
regulation of immune responseGO:00507762010.012
response to organophosphorusGO:0046683410.012
Rat
cell type specific apoptotic processGO:00972851250.012
anterior posterior axis specificationGO:000994820.012
cellular response to metal ionGO:0071248430.012
response to estrogenGO:0043627470.012
sleepGO:003043120.012

HMGCS2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.097
inherited metabolic disorderDOID:6552420.091
immune system diseaseDOID:29141550.030
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.021
sensory system diseaseDOID:00501552030.020
nervous system diseaseDOID:8634310.020
cardiovascular system diseaseDOID:12871060.019
eye and adnexa diseaseDOID:14921500.019
vascular diseaseDOID:178250.019
organ system cancerDOID:00506861640.019
eye diseaseDOID:56141490.018
musculoskeletal system diseaseDOID:172230.017
muscular diseaseDOID:00800001140.017
muscle tissue diseaseDOID:661130.017
myopathyDOID:4231040.017
central nervous system diseaseDOID:3311860.016
neurodegenerative diseaseDOID:12891020.014
amino acid metabolic disorderDOID:9252500.014