Homo sapiens

72 known processes

SPINK5

serine peptidase inhibitor, Kazal type 5

(Aliases: FLJ97596,FLJ99794,LETKI,LEKTI,FLJ21544,DKFZp686K19184,VAKTI,NS,NETS,FLJ97536)

SPINK5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
keratinizationGO:003142420.150
system processGO:00030083490.087
keratinocyte differentiationGO:0030216360.066
skin developmentGO:0043588760.065
epithelium developmentGO:00604292270.064
post embryonic developmentGO:000979120.063
epithelial cell differentiationGO:00308551410.061
cellular ketone metabolic processGO:0042180800.057
chemical homeostasisGO:00488783060.057
epidermal cell differentiationGO:0009913450.056
epidermis morphogenesisGO:004873030.054
protein maturationGO:00516042330.053
ras protein signal transductionGO:0007265730.051
multicellular organismal homeostasisGO:0048871670.051
small gtpase mediated signal transductionGO:0007264780.047
lipid metabolic processGO:00066293810.044
transmembrane transportGO:00550853990.043
epidermis developmentGO:0008544590.043
positive regulation of cell proliferationGO:00082843010.041
defense responseGO:00069523150.041
cellular chemical homeostasisGO:00550821800.040
cellular lipid metabolic processGO:00442553030.039
protein processingGO:00164852260.039
multicellular organismal agingGO:001025930.039
amine metabolic processGO:0009308440.038
cellular amine metabolic processGO:0044106410.038
ion homeostasisGO:00508012300.038
immune responseGO:00069553070.038
regulation of cellular ketone metabolic processGO:0010565500.038
cellular amino acid metabolic processGO:00065201160.038
negative regulation of cellular protein metabolic processGO:00322693530.037
regulation of cellular amino acid metabolic processGO:000652160.037
nucleoside phosphate catabolic processGO:19012924120.036
signal transduction by phosphorylationGO:00230142970.036
negative regulation of catalytic activityGO:00430863350.035
cellular homeostasisGO:00197251960.035
determination of adult lifespanGO:000834020.035
negative regulation of programmed cell deathGO:00430693210.034
negative regulation of cell proliferationGO:00082852280.034
ribonucleoside catabolic processGO:00424544060.034
purine containing compound catabolic processGO:00725234110.034
cytokine productionGO:00018162470.034
epithelial cell proliferationGO:00506731280.033
purine ribonucleoside metabolic processGO:00461284370.033
regulation of cytokine productionGO:00018172320.033
single organism cellular localizationGO:19025803320.033
negative regulation of protein metabolic processGO:00512483910.032
single organism membrane organizationGO:00448022680.032
actin filament based movementGO:0030048170.032
regulation of proteolysisGO:00301622930.032
ion transmembrane transportGO:00342203380.032
response to other organismGO:00517072610.032
neurological system processGO:00508771630.031
cation homeostasisGO:00550801890.031
cellular ion homeostasisGO:00068731680.031
positive regulation of transportGO:00510503360.031
cell adhesionGO:00071553250.031
rho protein signal transductionGO:0007266260.031
regulation of cellular amine metabolic processGO:0033238110.030
secretionGO:00469032540.030
startle responseGO:000196430.030
cytoplasmic transportGO:00164823790.029
cell morphogenesisGO:00009022960.029
positive regulation of phosphorylationGO:00423273940.029
female gamete generationGO:000729220.029
anion transportGO:00068201610.029
actin filament based processGO:00300292240.029
purine nucleoside catabolic processGO:00061523980.029
muscle system processGO:0003012810.029
negative regulation of apoptotic processGO:00430663160.029
ribonucleotide catabolic processGO:00092614050.029
cellular cation homeostasisGO:00300031630.029
regulation of mapk cascadeGO:00434082620.028
oogenesisGO:004847720.028
tissue homeostasisGO:0001894630.028
biological adhesionGO:00226103310.028
regulation of protein kinase activityGO:00458592890.027
endomembrane system organizationGO:00102561960.027
nucleoside triphosphate metabolic processGO:00091414220.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
positive regulation of hydrolase activityGO:00513453310.027
cardiac muscle cell contractionGO:008600340.027
response to organic cyclic compoundGO:00140702040.027
cellular component morphogenesisGO:00329893140.027
regenerationGO:003109940.027
organophosphate catabolic processGO:00464344300.027
regulation of transferase activityGO:00513383550.027
negative regulation of developmental processGO:00510932470.026
negative regulation of multicellular organismal processGO:00512413170.026
inorganic ion transmembrane transportGO:00986602310.026
cellular response to histamineGO:007142030.026
regulation of protein localizationGO:00328802960.026
metal ion homeostasisGO:00550651690.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
positive regulation of acrosome reactionGO:200034440.026
response to biotic stimulusGO:00096072760.025
positive regulation of cellular amine metabolic processGO:003324070.025
regulation of nucleotide metabolic processGO:00061402690.025
membrane organizationGO:00610242920.025
purine ribonucleotide catabolic processGO:00091544040.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
negative regulation of cell deathGO:00605483450.025
purine ribonucleoside catabolic processGO:00461303980.025
regulation of intracellular transportGO:00323861950.025
nucleoside triphosphate catabolic processGO:00091433940.025
purine nucleotide catabolic processGO:00061954050.025
vesicle mediated transportGO:00161923710.025
positive regulation of immune system processGO:00026842830.024
regulation of kinase activityGO:00435493140.024
nucleotide catabolic processGO:00091664080.024
locomotory behaviorGO:000762610.024
glycosyl compound catabolic processGO:19016584130.024
carbohydrate derivative biosynthetic processGO:19011372070.024
positive regulation of mapk cascadeGO:00434101900.024
innate immune responseGO:00450871780.024
synaptic transmission glycinergicGO:006001210.024
response to lipidGO:00339932060.024
positive regulation of nucleotide metabolic processGO:00459812300.023
g protein coupled receptor signaling pathwayGO:00071862070.023
negative regulation of phosphorus metabolic processGO:00105632670.023
regulation of cell cycleGO:00517263930.023
regulation of cell differentiationGO:00455953930.023
anatomical structure homeostasisGO:00602491000.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
epithelium migrationGO:00901321190.023
carbohydrate metabolic processGO:00059752070.023
positive regulation of transferase activityGO:00513472270.023
muscle contractionGO:0006936730.022
protein oligomerizationGO:00512591730.022
cation transportGO:00068123310.022
negative regulation of protein processingGO:00109551420.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
oxidation reduction processGO:00551143960.022
serotonin uptakeGO:005161020.022
regulation of actin filament based processGO:00329701410.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
morphogenesis of embryonic epitheliumGO:001633140.022
cell activationGO:00017752130.022
positive regulation of cellular catabolic processGO:00313312840.022
regulation of endopeptidase activityGO:00525481700.022
protein localization to organelleGO:00333652800.021
response to external biotic stimulusGO:00432072610.021
regulation of purine nucleotide metabolic processGO:19005422640.021
nucleoside catabolic processGO:00091644080.021
neuromuscular junction developmentGO:000752830.021
mitotic cell cycleGO:00002783260.021
regulation of anatomical structure morphogenesisGO:00226032860.021
regulation of peptidase activityGO:00525471800.021
negative regulation of phosphate metabolic processGO:00459362670.021
regulation of cytoplasmic transportGO:19036491490.021
cellular metal ion homeostasisGO:00068751460.021
positive regulation of cellular amino acid metabolic processGO:004576430.020
positive regulation of catabolic processGO:00098963100.020
response to oxygen containing compoundGO:19017003690.020
cellular response to endogenous stimulusGO:00714953360.020
organic hydroxy compound metabolic processGO:19016151470.020
memoryGO:000761330.020
negative regulation of hydrolase activityGO:00513461820.020
cardiac muscle contractionGO:0060048340.020
9 cis retinoic acid metabolic processGO:004290510.020
response to abiotic stimulusGO:00096283360.020
regulation of protein processingGO:00706131500.020
segmentationGO:003528240.020
apoptotic signaling pathwayGO:00971902680.020
positive regulation of cellular component organizationGO:00511303760.020
single organism carbohydrate metabolic processGO:00447231930.020
organonitrogen compound biosynthetic processGO:19015662000.020
regulation of nucleoside metabolic processGO:00091182090.020
intracellular protein transportGO:00068862700.020
hormone metabolic processGO:0042445610.020
dephosphorylationGO:00163112090.019
blood vessel morphogenesisGO:00485141620.019
mapk cascadeGO:00001652880.019
blood circulationGO:00080151130.019
negative regulation of protein maturationGO:19033181420.019
regulation of gtpase activityGO:00430871800.019
secretion by cellGO:00329402260.019
tissue regenerationGO:004224630.019
cellular response to oxygen containing compoundGO:19017012760.019
protein localization to plasma membraneGO:0072659930.019
regulation of establishment of protein localizationGO:00702012420.019
regulation of cell motilityGO:20001452990.019
plasma membrane organizationGO:00070091150.018
protein localization to membraneGO:00726571600.018
regulation of cellular response to stressGO:00801352440.018
immune effector processGO:00022521590.018
cell projection organizationGO:00300302520.018
protein catabolic processGO:00301633250.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of cell adhesionGO:00301551660.018
cellular divalent inorganic cation homeostasisGO:00725031280.018
blastoderm segmentationGO:000735020.018
growthGO:00400072020.018
regulation of nucleotide catabolic processGO:00308112050.018
guanosine containing compound catabolic processGO:19010692390.018
positive regulation of cell deathGO:00109422630.018
negative regulation of proteolysisGO:00458611320.018
regulation of secretion by cellGO:19035301770.018
regulation of protein transportGO:00512232130.018
positive regulation of cytokine productionGO:00018191670.018
regulation of cell cycle processGO:00105642660.018
mitotic cell cycle processGO:19030472860.018
positive regulation of protein phosphorylationGO:00019343130.018
oocyte developmentGO:004859910.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
epithelial cell migrationGO:00106311190.017
small molecule biosynthetic processGO:00442831570.017
positive regulation of kinase activityGO:00336742040.017
establishment of protein localization to membraneGO:00901501210.017
actin mediated cell contractionGO:0070252120.017
anterior posterior axis specificationGO:000994820.017
organophosphate biosynthetic processGO:00904071630.017
regulation of secretionGO:00510461940.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
single organism cell adhesionGO:00986021790.017
gtp metabolic processGO:00460392390.017
guanosine containing compound metabolic processGO:19010682440.017
regulation of epithelial cell proliferationGO:00506781130.017
regulation of cellular component movementGO:00512703340.017
striated muscle contractionGO:0006941520.017
cellular response to dna damage stimulusGO:00069743790.017
monocarboxylic acid metabolic processGO:00327871850.017
blood vessel developmentGO:00015681720.017
positive regulation of apoptotic processGO:00430652460.017
positive regulation of developmental processGO:00510943140.017
positive regulation of nucleoside metabolic processGO:00459791860.016
oocyte differentiationGO:000999420.016
regulation of growthGO:00400081650.016
negative regulation of endopeptidase activityGO:0010951840.016
cellular macromolecule catabolic processGO:00442653800.016
regulation of protein maturationGO:19033171500.016
nervous system developmentGO:00073992930.016
divalent inorganic cation transportGO:00725111580.016
positive regulation of nucleotide catabolic processGO:00308131850.016
gtp catabolic processGO:00061842370.016
matingGO:000761810.016
negative regulation of phosphorylationGO:00423261740.016
alcohol metabolic processGO:00060661140.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
positive regulation of protein kinase activityGO:00458601900.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
negative regulation of protein modification processGO:00314002000.016
inseminationGO:000732010.016
regulation of purine nucleotide catabolic processGO:00331212050.016
protein targetingGO:00066051870.016
steroid metabolic processGO:0008202940.016
nucleotide biosynthetic processGO:00091651090.016
regulation of mitotic cell cycleGO:00073461890.016
copulationGO:000762010.016
tissue migrationGO:00901301190.015
cellular macromolecular complex assemblyGO:00346223240.015
posttranscriptional regulation of gene expressionGO:00106082130.015
regulation of immune responseGO:00507762010.015
negative regulation of intracellular signal transductionGO:19025321830.015
metal ion transportGO:00300012720.015
regulation of locomotionGO:00400123290.015
maintenance of locationGO:00512351120.015
cellular protein catabolic processGO:00442572610.015
positive regulation of programmed cell deathGO:00430682490.015
regulation of membrane potentialGO:0042391950.015
positive regulation of organelle organizationGO:00106381950.015
cellular response to organic cyclic compoundGO:00714071270.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of multi organism processGO:00439001570.015
divalent inorganic cation homeostasisGO:00725071360.015
melanin metabolic processGO:000658210.015
associative learningGO:000830610.015
positive regulation of gtpase activityGO:00435471660.015
cardiovascular system developmentGO:00723582620.015
chromatin modificationGO:00165682980.015
compound eye developmentGO:004874910.015
angiogenesisGO:00015251470.015
calcium ion transportGO:00068161470.015
regulation of small gtpase mediated signal transductionGO:00510561560.014
regulation of protein serine threonine kinase activityGO:00719001790.014
cell growthGO:00160491600.014
circulatory system developmentGO:00723592620.014
activation of immune responseGO:00022531140.014
sensory perceptionGO:00076001030.014
histone modificationGO:00165702510.014
calcium ion homeostasisGO:00550741220.014
protein ubiquitinationGO:00165673140.014
peripheral nervous system developmentGO:000742220.014
chromatin organizationGO:00063253510.014
monovalent inorganic cation transportGO:00156721280.014
negative regulation of cell migrationGO:00303361020.014
organic acid biosynthetic processGO:0016053970.014
protein homooligomerizationGO:00512601000.014
nuclear transportGO:00511691790.014
regulation of gtp catabolic processGO:00331241800.014
actin cytoskeleton organizationGO:00300362070.014
positive regulation of secretion by cellGO:19035321080.014
nucleocytoplasmic transportGO:00069131760.014
inorganic cation transmembrane transportGO:00986621940.014
divalent metal ion transportGO:00708381520.014
regulation of cell migrationGO:00303342890.014
response to cytokineGO:00340972320.014
spermatid differentiationGO:004851540.014
sequestering of metal ionGO:0051238240.014
negative regulation of cellular component organizationGO:00511292350.014
salivary gland morphogenesisGO:000743540.014
positive regulation of secretionGO:00510471160.014
regulation of vesicle mediated transportGO:00606271300.014
hair follicle morphogenesisGO:003106920.014
regulation of intracellular protein transportGO:00331571230.014
positive regulation of cellular component movementGO:00512721810.014
anterior posterior axis specification embryoGO:000859520.013
regulation of protein catabolic processGO:00421761550.013
cellular response to nitrogen compoundGO:19016991440.013
tube developmentGO:00352951250.013
establishment of protein localization to organelleGO:00725941720.013
regulation of meiotic cell cycleGO:005144540.013
cell divisionGO:00513011680.013
positive regulation of epithelial cell proliferationGO:0050679650.013
rhythmic behaviorGO:000762220.013
embryonic epithelial tube formationGO:000183840.013
sensory perception of painGO:001923340.013
sequestering of calcium ionGO:0051208170.013
cellular response to cytokine stimulusGO:00713451810.013
microtubule based processGO:00070172100.013
gamma aminobutyric acid signaling pathwayGO:000721430.013
cation transmembrane transportGO:00986552380.013
covalent chromatin modificationGO:00165692540.013
response to fungusGO:000962040.013
chloride transmembrane transportGO:1902476380.013
positive regulation of ras gtpase activityGO:00323201170.013
nitrogen compound transportGO:00717051910.013
protein modification by small protein conjugationGO:00324463420.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
regulation of response to external stimulusGO:00321012220.013
regulation of cellular component biogenesisGO:00440872810.013
response to woundingGO:00096111680.013
cellular calcium ion homeostasisGO:00068741170.013
multicellular organismal signalingGO:0035637340.013
positive regulation of protein transportGO:00512221350.013
inorganic anion transmembrane transportGO:0098661470.013
negative regulation of cell differentiationGO:00455961710.013
response to hormoneGO:00097251750.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of apoptotic signaling pathwayGO:20012331750.013
ossificationGO:00015031210.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
i kappab kinase nf kappab signalingGO:00072491660.013
regulation of dna metabolic processGO:00510521530.013
retina homeostasisGO:0001895420.012
single organismal cell cell adhesionGO:00163371480.012
response to bacteriumGO:00096171440.012
positive regulation of gtp catabolic processGO:00331261660.012
regulation of ion transportGO:00432691890.012
sodium ion transmembrane transportGO:0035725590.012
tripartite regional subdivisionGO:000735120.012
organic anion transportGO:00157111030.012
cell envelope organizationGO:004316310.012
ameboidal type cell migrationGO:00016671350.012
viral processGO:00160321460.012
reactive nitrogen species metabolic processGO:200105730.012
spermatid developmentGO:000728640.012
inorganic anion transportGO:0015698600.012
chloride transportGO:0006821410.012
carboxylic acid biosynthetic processGO:0046394970.012
fatty acid metabolic processGO:00066311150.012
organelle assemblyGO:00709251760.012
positive regulation of cell differentiationGO:00455972110.012
endocytosisGO:00068971590.012
leukocyte activationGO:00453211640.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
taxisGO:00423301570.012
neurogenesisGO:00220081690.012
positive regulation of proteolysisGO:00458621420.012
negative regulation of transferase activityGO:00513481240.012
regulation of ras gtpase activityGO:00323181280.012
cellular response to lipidGO:00713961270.012
prostate gland developmentGO:003085030.012
positive regulation of plasminogen activationGO:001075630.012
cell developmentGO:00484683280.012
glial cell migrationGO:000834740.012
cell projection assemblyGO:00300311260.012
regulation of map kinase activityGO:00434051080.012
regulation of cell activationGO:00508651250.012
negative regulation of neurological system processGO:003164520.012
reactive oxygen species metabolic processGO:0072593750.012
positive regulation of cell cycleGO:00457871400.012
regulation of protein targetingGO:1903533910.012
t cell differentiation in thymusGO:003307740.012
wound healingGO:00420601150.012
positive regulation of cell migrationGO:00303351720.012
negative regulation of peptidase activityGO:0010466910.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
positive regulation of immune responseGO:00507781590.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
regulation of cell divisionGO:00513021160.011
regulation of cytoskeleton organizationGO:00514931770.011
androgen biosynthetic processGO:000670230.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
cell part morphogenesisGO:00329901370.011
regulation of neural precursor cell proliferationGO:200017740.011
response to organonitrogen compoundGO:00102431560.011
lipid biosynthetic processGO:00086101770.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
response to virusGO:00096151260.011
circulatory system processGO:00030131130.011
regulation of system processGO:00440571010.011
cellular protein complex assemblyGO:00436231880.011
motor neuron axon guidanceGO:000804520.011
negative regulation of interferon gamma secretionGO:190271410.011
protein importGO:00170381300.011
somitogenesisGO:000175620.011
mitochondrion organizationGO:00070051560.011
negative regulation of cell cycleGO:00457861930.011
angiotensin activated signaling pathwayGO:003816640.011
response to nitrogen compoundGO:19016981840.011
hindlimb morphogenesisGO:003513720.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
energy homeostasisGO:009700930.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
visual behaviorGO:000763220.011
regulation of viral processGO:00507921030.011
regulation of systemic arterial blood pressure by atrial natriuretic peptideGO:000305010.011
cellular response to ammonium ionGO:007124240.011
positive regulation of locomotionGO:00400171860.011
cell cell signalingGO:00072671550.011
response to metal ionGO:0010038840.011
homotypic cell cell adhesionGO:0034109470.011
neural tube closureGO:000184330.011
vasculature developmentGO:00019441810.011
tissue morphogenesisGO:0048729960.011
positive regulation of cellular component biogenesisGO:00440891580.011
cell cycle phase transitionGO:00447701730.011
nerve developmentGO:002167540.011
regulation of hormone levelsGO:00108171250.011
regulation of nucleocytoplasmic transportGO:0046822980.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of organic acid transportGO:003289230.011
regulation of homeostatic processGO:00328441210.011
response to axon injuryGO:004867810.011
meiotic chromosome segregationGO:004513240.011
monocarboxylic acid biosynthetic processGO:0072330670.011
regulation of metal ion transportGO:00109591200.011
atp metabolic processGO:00460341760.011
catagenGO:004263730.011
lipid localizationGO:00108761060.011
generation of neuronsGO:00486991520.011
cellular response to organonitrogen compoundGO:00714171240.010
av node cell to bundle of his cell communicationGO:008606740.010
endosomal transportGO:00161971290.010
response to caffeineGO:003100030.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
negative regulation of catabolic processGO:00098951040.010
modification dependent macromolecule catabolic processGO:00436322120.010
protein import into nucleusGO:00066061040.010
response to inorganic substanceGO:00100351270.010
terpenoid metabolic processGO:0006721270.010
regulation of phosphatase activityGO:0010921810.010
cellular response to external stimulusGO:00714961110.010
syncytium formation by plasma membrane fusionGO:000076820.010
positive regulation of cell cycle processGO:00900681060.010
modification dependent protein catabolic processGO:00199412090.010
interspecies interaction between organismsGO:00444191560.010
defense response to other organismGO:00985421290.010
hindbrain developmentGO:003090230.010
action potentialGO:0001508340.010
regulation of dephosphorylationGO:0035303960.010
protein localization to nucleusGO:00345041360.010
midgut developmentGO:000749410.010
peptide cross linkingGO:0018149120.010
golgi to plasma membrane cftr protein transportGO:004300010.010
basement membrane organizationGO:007171130.010
adult locomotory behaviorGO:000834410.010
microtubule cytoskeleton organizationGO:00002261760.010
anion transmembrane transportGO:0098656760.010
rna processingGO:00063962550.010
photoreceptor cell differentiationGO:004653020.010

SPINK5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.021
nervous system diseaseDOID:8634310.020
central nervous system diseaseDOID:3311860.020
organ system cancerDOID:00506861640.019
musculoskeletal system diseaseDOID:172230.018
sensory system diseaseDOID:00501552030.017
disease of metabolismDOID:00146672950.017
inherited metabolic disorderDOID:6552420.015
eye and adnexa diseaseDOID:14921500.014
neurodegenerative diseaseDOID:12891020.013
retinal diseaseDOID:56791180.012
eye diseaseDOID:56141490.012
retinal degenerationDOID:8466890.012
immune system diseaseDOID:29141550.012
connective tissue diseaseDOID:651090.011
gastrointestinal system cancerDOID:3119520.011
bone diseaseDOID:0080001880.010