Homo sapiens

11 known processes

HPD

4-hydroxyphenylpyruvate dioxygenase

(Aliases: HPPDASE,4-HPPD,4HPPD,GLOD3,PPD)

HPD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule biosynthetic processGO:00442831570.461
lipid metabolic processGO:00066293810.422
monocarboxylic acid metabolic processGO:00327871850.349
cellular amino acid metabolic processGO:00065201160.313
cellular lipid metabolic processGO:00442553030.306
cellular ketone metabolic processGO:0042180800.285
response to oxygen containing compoundGO:19017003690.279
carboxylic acid biosynthetic processGO:0046394970.247
anion transportGO:00068201610.243
chemical homeostasisGO:00488783060.243
organic anion transportGO:00157111030.227
organic hydroxy compound metabolic processGO:19016151470.200
fatty acid metabolic processGO:00066311150.198
lipid biosynthetic processGO:00086101770.191
organic acid biosynthetic processGO:0016053970.188
organic hydroxy compound transportGO:0015850630.178
steroid metabolic processGO:0008202940.170
long chain fatty acid metabolic processGO:0001676300.156
urate transportGO:001574730.143
regulation of cellular ketone metabolic processGO:0010565500.143
phylloquinone metabolic processGO:004237420.142
cellular amine metabolic processGO:0044106410.142
oxidation reduction processGO:00551143960.141
cellular response to oxygen containing compoundGO:19017012760.138
monocarboxylic acid biosynthetic processGO:0072330670.130
sulfur compound metabolic processGO:00067901010.127
ion homeostasisGO:00508012300.112
cofactor metabolic processGO:0051186870.100
protein processingGO:00164852260.099
lipid catabolic processGO:0016042840.097
immune responseGO:00069553070.096
lipid transportGO:0006869900.096
amine metabolic processGO:0009308440.094
regulation of high density lipoprotein particle clearanceGO:001098220.092
positive regulation of cellular amine metabolic processGO:003324070.086
alcohol metabolic processGO:00060661140.085
regulation of response to external stimulusGO:00321012220.083
carboxylic acid transportGO:0046942630.081
regulation of cellular amino acid metabolic processGO:000652160.079
lipid localizationGO:00108761060.076
positive regulation of transportGO:00510503360.073
urate metabolic processGO:0046415110.073
protein maturationGO:00516042330.073
post embryonic developmentGO:000979120.073
transmembrane transportGO:00550853990.072
defense responseGO:00069523150.070
response to organonitrogen compoundGO:00102431560.070
small molecule catabolic processGO:0044282920.068
ion transmembrane transportGO:00342203380.068
negative regulation of protein metabolic processGO:00512483910.067
regulation of response to woundingGO:19030341010.065
organic acid transportGO:0015849650.064
alpha ketoglutarate transportGO:001574210.062
positive regulation of cellular amino acid metabolic processGO:004576430.061
biological adhesionGO:00226103310.059
epoxygenase p450 pathwayGO:001937330.059
vitamin k catabolic processGO:004237720.059
response to other organismGO:00517072610.058
response to nitrogen compoundGO:19016981840.058
cation transportGO:00068123310.057
regenerationGO:003109940.055
system processGO:00030083490.055
regulation of cellular amine metabolic processGO:0033238110.053
glycerolipid metabolic processGO:00464861070.053
menaquinone catabolic processGO:004236120.052
carbohydrate metabolic processGO:00059752070.052
regulation of peptidase activityGO:00525471800.051
negative regulation of cellular protein metabolic processGO:00322693530.050
negative regulation of transportGO:00510511760.050
positive regulation of cell deathGO:00109422630.050
positive regulation of cell proliferationGO:00082843010.050
regulation of proteolysisGO:00301622930.049
regulation of immune responseGO:00507762010.048
neutral lipid catabolic processGO:0046461120.048
positive regulation of immune responseGO:00507781590.048
purine ribonucleoside metabolic processGO:00461284370.047
innate immune responseGO:00450871780.047
regulation of lipid metabolic processGO:0019216960.047
response to woundingGO:00096111680.047
negative regulation of catalytic activityGO:00430863350.046
fatty acid omega oxidationGO:001043020.046
alpha amino acid metabolic processGO:1901605720.046
positive regulation of cell migrationGO:00303351720.046
carboxylic acid catabolic processGO:0046395710.045
positive regulation of immune system processGO:00026842830.045
regulation of defense responseGO:00313471540.045
organic hydroxy compound biosynthetic processGO:1901617710.044
response to organic cyclic compoundGO:00140702040.044
negative regulation of protein maturationGO:19033181420.044
cellular modified amino acid metabolic processGO:0006575640.044
nitrogen compound transportGO:00717051910.044
multicellular organismal agingGO:001025930.043
response to bacteriumGO:00096171440.043
response to external biotic stimulusGO:00432072610.043
organic acid catabolic processGO:0016054710.043
positive regulation of programmed cell deathGO:00430682490.042
coenzyme metabolic processGO:0006732650.042
response to inorganic substanceGO:00100351270.042
response to biotic stimulusGO:00096072760.041
fatty acid biosynthetic processGO:0006633460.041
organonitrogen compound biosynthetic processGO:19015662000.040
positive regulation of protein phosphorylationGO:00019343130.040
determination of adult lifespanGO:000834020.040
apoptotic signaling pathwayGO:00971902680.039
regulation of cytokine productionGO:00018172320.038
response to lipidGO:00339932060.038
positive regulation of cellular component movementGO:00512721810.038
regulation of cell migrationGO:00303342890.038
cation homeostasisGO:00550801890.038
negative regulation of programmed cell deathGO:00430693210.038
vitamin e metabolic processGO:004236010.037
inflammatory responseGO:0006954790.037
metal ion transportGO:00300012720.037
regulation of lipid biosynthetic processGO:0046890470.037
organophosphate catabolic processGO:00464344300.036
positive regulation of phosphorylationGO:00423273940.036
quinone catabolic processGO:190166220.036
regulation of protein maturationGO:19033171500.036
ribonucleoside triphosphate metabolic processGO:00091994120.036
regulation of endopeptidase activityGO:00525481700.035
cell adhesionGO:00071553250.035
regulation of protein processingGO:00706131500.035
purine ribonucleoside triphosphate catabolic processGO:00092073910.035
mapk cascadeGO:00001652880.034
segmentationGO:003528240.034
positive regulation of catabolic processGO:00098963100.034
negative regulation of icosanoid secretionGO:003230420.033
secretionGO:00469032540.033
carnitine transmembrane transportGO:190260330.033
single organism carbohydrate metabolic processGO:00447231930.033
blood vessel developmentGO:00015681720.033
metal ion homeostasisGO:00550651690.033
positive regulation of cell motilityGO:20001471770.032
alkaloid metabolic processGO:000982040.032
cellular chemical homeostasisGO:00550821800.032
regulation of body fluid levelsGO:0050878990.032
positive regulation of apoptotic processGO:00430652460.032
cellular lipid catabolic processGO:0044242650.031
nucleoside triphosphate metabolic processGO:00091414220.031
positive regulation of intestinal epithelial structure maintenanceGO:006073110.031
atp metabolic processGO:00460341760.031
positive regulation of cytokine productionGO:00018191670.031
ribonucleoside catabolic processGO:00424544060.031
regulation of cellular component movementGO:00512703340.031
cellular homeostasisGO:00197251960.030
cytokine productionGO:00018162470.030
maintenance of locationGO:00512351120.030
cell activationGO:00017752130.030
purine ribonucleoside monophosphate metabolic processGO:00091671860.030
negative regulation of protein processingGO:00109551420.030
response to drugGO:0042493810.030
negative regulation of multicellular organismal processGO:00512413170.030
epithelial cell proliferationGO:00506731280.030
purine containing compound catabolic processGO:00725234110.029
thyroid hormone transportGO:007032720.029
ribonucleotide catabolic processGO:00092614050.029
epithelium migrationGO:00901321190.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
anion transmembrane transportGO:0098656760.029
purine ribonucleotide catabolic processGO:00091544040.029
renal tubular secretionGO:009725410.029
regulation of ion transportGO:00432691890.029
regulation of protein kinase activityGO:00458592890.029
negative regulation of cellular amine metabolic processGO:003323930.029
response to organophosphorusGO:0046683410.028
negative regulation of phosphate metabolic processGO:00459362670.028
cellular amino acid biosynthetic processGO:0008652300.028
unsaturated fatty acid metabolic processGO:0033559370.028
interspecies interaction between organismsGO:00444191560.028
carbohydrate derivative biosynthetic processGO:19011372070.028
negative regulation of cell deathGO:00605483450.028
hematopoietic or lymphoid organ developmentGO:00485341860.028
regulation of kinase activityGO:00435493140.028
memoryGO:000761330.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
cytoplasmic transportGO:00164823790.027
icosanoid metabolic processGO:0006690350.027
regulation of anatomical structure morphogenesisGO:00226032860.027
9 cis retinoic acid metabolic processGO:004290510.027
negative regulation of hydrolase activityGO:00513461820.026
menaquinone metabolic processGO:000923330.026
female gamete generationGO:000729220.026
purine nucleoside catabolic processGO:00061523980.026
positive regulation of developmental processGO:00510943140.026
nucleoside monophosphate metabolic processGO:00091231910.026
steroid biosynthetic processGO:0006694460.026
regulation of cellular response to stressGO:00801352440.025
immune system developmentGO:00025201950.025
positive regulation of digestive system processGO:006045620.025
nucleoside phosphate catabolic processGO:19012924120.025
cation transmembrane transportGO:00986552380.025
nucleotide catabolic processGO:00091664080.025
negative regulation of apoptotic processGO:00430663160.025
regulation of protein serine threonine kinase activityGO:00719001790.025
positive regulation of cellular catabolic processGO:00313312840.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
purine nucleotide catabolic processGO:00061954050.024
immune effector processGO:00022521590.024
positive regulation of cellular component organizationGO:00511303760.024
nervous system developmentGO:00073992930.024
positive regulation of locomotionGO:00400171860.024
cardiac muscle cell contractionGO:008600340.024
nucleoside triphosphate catabolic processGO:00091433940.024
leukocyte activationGO:00453211640.024
positive regulation of icosanoid secretionGO:003230530.024
negative regulation of response to woundingGO:1903035470.024
vasculature developmentGO:00019441810.024
response to hormoneGO:00097251750.024
actin filament based movementGO:0030048170.023
icosanoid catabolic processGO:190152320.023
protein homooligomerizationGO:00512601000.023
small gtpase mediated signal transductionGO:0007264780.023
regulation of cell differentiationGO:00455953930.023
quorum sensing involved in interaction with hostGO:005210610.023
vitamin k biosynthetic processGO:004237120.023
cellular hormone metabolic processGO:0034754410.023
negative regulation of cellular component organizationGO:00511292350.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
hemopoiesisGO:00300971800.023
response to extracellular stimulusGO:0009991850.023
leukotriene catabolic processGO:003610020.023
vesicle mediated transportGO:00161923710.023
regulation of mapk cascadeGO:00434082620.023
locomotory behaviorGO:000762610.023
tissue migrationGO:00901301190.022
negative regulation of phosphorus metabolic processGO:00105632670.022
positive regulation of hydrolase activityGO:00513453310.022
cholesterol transportGO:0030301390.022
peptidyl tyrosine phosphorylationGO:00181081700.022
symbiosis encompassing mutualism through parasitismGO:00444031560.022
cell morphogenesisGO:00009022960.022
response to abiotic stimulusGO:00096283360.022
regulation of protein localizationGO:00328802960.022
naphthalene metabolic processGO:001893110.022
regulation of cell adhesionGO:00301551660.022
hormone metabolic processGO:0042445610.022
negative regulation of proteolysisGO:00458611320.022
cellular amide metabolic processGO:0043603690.022
cell type specific apoptotic processGO:00972851250.022
response to cytokineGO:00340972320.022
cellular response to endogenous stimulusGO:00714953360.022
regulation of vesicle mediated transportGO:00606271300.021
regulation of purine nucleotide metabolic processGO:19005422640.021
protein oligomerizationGO:00512591730.021
phenylpropanoid metabolic processGO:000969830.021
regulation of transferase activityGO:00513383550.021
lipid modificationGO:0030258840.021
negative regulation of cell proliferationGO:00082852280.021
purine ribonucleoside catabolic processGO:00461303980.021
purine nucleoside monophosphate metabolic processGO:00091261860.021
lipid homeostasisGO:0055088390.021
sodium dependent organic cation transportGO:007071510.021
circulatory system developmentGO:00723592620.021
cholesterol homeostasisGO:0042632280.021
epithelium developmentGO:00604292270.021
regulation of hormone levelsGO:00108171250.021
mitochondrion organizationGO:00070051560.021
response to metal ionGO:0010038840.021
regulation of multi organism processGO:00439001570.021
endocytosisGO:00068971590.020
leukotriene metabolic processGO:0006691100.020
regulation of secretionGO:00510461940.020
signal transduction by phosphorylationGO:00230142970.020
demethylationGO:0070988370.020
positive regulation of secretionGO:00510471160.020
single organism cellular localizationGO:19025803320.020
glycosyl compound catabolic processGO:19016584130.020
regulation of protein transportGO:00512232130.020
regulation of intracellular transportGO:00323861950.020
regulation of cytoplasmic transportGO:19036491490.020
cellular carbohydrate metabolic processGO:0044262840.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
regulation of locomotionGO:00400123290.020
homeostasis of number of cells in a free living populationGO:004887410.019
reactive nitrogen species metabolic processGO:200105730.019
cellular response to organonitrogen compoundGO:00714171240.019
nucleoside catabolic processGO:00091644080.019
actin mediated cell contractionGO:0070252120.019
oogenesisGO:004847720.019
arachidonic acid metabolic processGO:0019369140.019
organophosphate biosynthetic processGO:00904071630.019
regulation of lipid transportGO:0032368440.019
sodium independent organic anion transportGO:004325220.019
cellular response to lipidGO:00713961270.019
regulation of apoptotic signaling pathwayGO:20012331750.019
oxidative demethylationGO:0070989110.019
cellular response to nitrogen compoundGO:19016991440.019
divalent metal ion transportGO:00708381520.019
response to fungusGO:000962040.019
cellular ion homeostasisGO:00068731680.019
growthGO:00400072020.019
regulation of cell motilityGO:20001452990.019
cellular response to xenobiotic stimulusGO:0071466290.019
cell cell signalingGO:00072671550.019
negative regulation of immune system processGO:00026831360.019
response to peptideGO:1901652650.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.018
monosaccharide metabolic processGO:0005996740.018
inorganic cation transmembrane transportGO:00986621940.018
protein catabolic processGO:00301633250.018
regulation of reactive oxygen species metabolic processGO:2000377410.018
defense response to fungusGO:005083240.018
nicotinate transportGO:200114210.018
blood vessel morphogenesisGO:00485141620.018
regulation of homeostatic processGO:00328441210.018
regulation of establishment of protein localizationGO:00702012420.018
wound healingGO:00420601150.018
zymogen activationGO:0031638700.018
cellular response to cytokine stimulusGO:00713451810.018
response to growth factorGO:00708482050.018
response to nutrient levelsGO:0031667810.018
regulation of nucleoside metabolic processGO:00091182090.018
regulation of dna metabolic processGO:00510521530.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
mitotic cell cycleGO:00002783260.018
positive regulation of protein kinase activityGO:00458601900.018
peptidyl tyrosine modificationGO:00182121700.018
regulation of cysteine type endopeptidase activityGO:20001161270.018
positive regulation of fatty acid transportGO:200019330.018
negative regulation of protein modification processGO:00314002000.018
single organismal cell cell adhesionGO:00163371480.017
regulation of synaptic plasticityGO:004816730.017
blood coagulationGO:0007596760.017
anterior posterior axis specificationGO:000994820.017
amino acid transportGO:0006865280.017
cardiovascular system developmentGO:00723582620.017
regulation of purine nucleotide catabolic processGO:00331212050.017
nuclear transportGO:00511691790.017
short chain fatty acid importGO:001591310.017
ras protein signal transductionGO:0007265730.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
regulation of nucleotide metabolic processGO:00061402690.017
cellular cation homeostasisGO:00300031630.017
neuromuscular junction developmentGO:000752830.017
isoprenoid metabolic processGO:0006720390.017
response to acid chemicalGO:0001101660.017
cellular response to oxidative stressGO:0034599850.017
regulation of cell cycle processGO:00105642660.017
negative regulation of phosphorylationGO:00423261740.017
multi organism cellular processGO:00447641560.017
positive regulation of organic acid transportGO:003289230.017
defense response to other organismGO:00985421290.017
regulation of protein catabolic processGO:00421761550.017
myeloid cell differentiationGO:00300991170.016
protein targetingGO:00066051870.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
regulation of vasculature developmentGO:1901342970.016
regulation of inflammatory responseGO:0050727460.016
coagulationGO:0050817780.016
cellular macromolecule catabolic processGO:00442653800.016
epithelial cell differentiationGO:00308551410.016
glycoprotein metabolic processGO:00091001100.016
negative regulation of cell cycleGO:00457861930.016
protein localization to organelleGO:00333652800.016
salivary gland morphogenesisGO:000743540.016
negative regulation of intracellular signal transductionGO:19025321830.016
reactive oxygen species biosynthetic processGO:190340940.016
posttranscriptional regulation of gene expressionGO:00106082130.016
sulfur compound biosynthetic processGO:0044272380.016
regulation of nucleotide catabolic processGO:00308112050.016
linoleic acid metabolic processGO:004365140.016
activation of immune responseGO:00022531140.016
regulation of cell activationGO:00508651250.016
cellular macromolecular complex assemblyGO:00346223240.016
glycoprotein biosynthetic processGO:0009101910.016
drug metabolic processGO:0017144190.016
blastoderm segmentationGO:000735020.016
forebrain regionalizationGO:002187130.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of icosanoid secretionGO:003230340.016
positive regulation of fibrinolysisGO:005191940.016
azole transportGO:004511740.016
regulation of leukocyte activationGO:00026941150.016
mature dendritic cell differentiationGO:009702920.016
cellular response to hormone stimulusGO:00328701250.016
glycerophospholipid metabolic processGO:0006650840.016
blood circulationGO:00080151130.016
renal water homeostasisGO:000309140.015
positive regulation of kinase activityGO:00336742040.015
fatty acid derivative metabolic processGO:1901568350.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
ameboidal type cell migrationGO:00016671350.015
mitotic cell cycle processGO:19030472860.015
positive regulation of response to external stimulusGO:0032103880.015
positive regulation of mapk cascadeGO:00434101900.015
purine containing compound biosynthetic processGO:0072522880.015
divalent inorganic cation homeostasisGO:00725071360.015
neutral lipid metabolic processGO:0006638270.015
regulation of epithelial cell proliferationGO:00506781130.015
epidermis morphogenesisGO:004873030.015
calcium ion transportGO:00068161470.015
negative regulation of cellular catabolic processGO:0031330830.015
defense response to bacteriumGO:0042742630.015
intracellular protein transportGO:00068862700.015
epithelial cell migrationGO:00106311190.015
regulation of system processGO:00440571010.015
positive regulation of ion transportGO:0043270870.015
actin filament based processGO:00300292240.015
response to activityGO:001482300.015
cellular response to external stimulusGO:00714961110.015
leukotriene b4 catabolic processGO:003610120.015
rho protein signal transductionGO:0007266260.015
regulation of wound healingGO:0061041560.015
regulation of epithelial cell migrationGO:0010632930.015
angiogenesisGO:00015251470.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
endothelial cell migrationGO:0043542860.015
positive regulation of nucleotide metabolic processGO:00459812300.015
negative regulation of growthGO:0045926970.015
reactive oxygen species metabolic processGO:0072593750.015
sterol homeostasisGO:0055092280.015
leukocyte differentiationGO:0002521980.015
response to xenobiotic stimulusGO:0009410300.015
androgen biosynthetic processGO:000670230.015
tissue regenerationGO:004224630.015
nucleocytoplasmic transportGO:00069131760.015
atp catabolic processGO:00062001570.015
secretion by cellGO:00329402260.015
cellular metal ion homeostasisGO:00068751460.015
diterpenoid metabolic processGO:0016101200.015
positive regulation of proteolysisGO:00458621420.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
response to molecule of bacterial originGO:0002237820.014
cellular response to abiotic stimulusGO:00712141170.014
positive regulation of cell differentiationGO:00455972110.014
central nervous system developmentGO:00074171230.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
sequestering of calcium ionGO:0051208170.014
regulation of mitotic cell cycle phase transitionGO:19019901180.014
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
dephosphorylationGO:00163112090.014
nucleoside monophosphate catabolic processGO:00091251590.014
negative regulation of gliogenesisGO:001401430.014
cellular protein complex assemblyGO:00436231880.014
negative regulation of peptidase activityGO:0010466910.014
positive regulation of transferase activityGO:00513472270.014
cellular organofluorine metabolic processGO:009034620.014
cellular response to growth factor stimulusGO:00713631970.014
sequestering of metal ionGO:0051238240.014
positive regulation of protein transportGO:00512221350.014
drinking behaviorGO:004275610.014
spermatid differentiationGO:004851540.014
positive regulation of synaptic transmissionGO:005080640.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
testosterone biosynthetic processGO:006137020.014
alcohol biosynthetic processGO:0046165520.014
cellular response to dna damage stimulusGO:00069743790.014
glial cell migrationGO:000834740.014
regulation of intracellular protein transportGO:00331571230.014
positive regulation of endopeptidase activityGO:0010950840.014
response to axon injuryGO:004867810.014
terpenoid metabolic processGO:0006721270.014
drug catabolic processGO:0042737100.014
calcium ion homeostasisGO:00550741220.013
cell developmentGO:00484683280.013
regulation of cytoskeleton organizationGO:00514931770.013
negative regulation of catabolic processGO:00098951040.013
digestionGO:0007586220.013
positive regulation of cysteine type endopeptidase activityGO:2001056790.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
regulation of coagulationGO:0050818440.013
cardiac muscle contractionGO:0060048340.013
cell projection organizationGO:00300302520.013
phospholipid metabolic processGO:0006644990.013
regulation of ion homeostasisGO:2000021730.013
cellular protein catabolic processGO:00442572610.013
sterol transportGO:0015918390.013
monocarboxylic acid transportGO:0015718320.013
hexose metabolic processGO:0019318550.013
regulation of transmembrane transporter activityGO:0022898740.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013

HPD disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.205
inherited metabolic disorderDOID:6552420.097
immune system diseaseDOID:29141550.043
hematopoietic system diseaseDOID:741000.035
kidney diseaseDOID:557360.028
renal tubular transport diseaseDOID:447110.028
urinary system diseaseDOID:18400.028
sensory system diseaseDOID:00501552030.025
nervous system diseaseDOID:8634310.025
steroid inherited metabolic disorderDOID:170190.022
lipid metabolism disorderDOID:3146260.022
cardiovascular system diseaseDOID:12871060.021
eye and adnexa diseaseDOID:14921500.020
musculoskeletal system diseaseDOID:172230.020
organ system cancerDOID:00506861640.018
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
central nervous system diseaseDOID:3311860.018
eye diseaseDOID:56141490.016
connective tissue diseaseDOID:651090.016
bone diseaseDOID:0080001880.016
vascular diseaseDOID:178250.014