Homo sapiens

89 known processes

KDM4A

lysine (K)-specific demethylase 4A

(Aliases: JMJD2,JMJD2A,JHDM3A,KIAA0677)

KDM4A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063253510.285
chromatin modificationGO:00165682980.269
cellular response to dna damage stimulusGO:00069743790.155
dna repairGO:00062811980.151
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.134
Yeast
regulation of cell differentiationGO:00455953930.132
Rat
histone h3 k79 methylationGO:003472920.130
dna replication dependent nucleosome assemblyGO:0006335320.126
dna replication dependent nucleosome organizationGO:0034723320.125
dna replication independent nucleosome organizationGO:0034724270.115
histone modificationGO:00165702510.113
covalent chromatin modificationGO:00165692540.113
anatomical structure formation involved in morphogenesisGO:00486462840.107
nucleotide excision repairGO:0006289310.101
regulation of cell cycle processGO:00105642660.096
dna replication independent nucleosome assemblyGO:0006336270.093
modification dependent macromolecule catabolic processGO:00436322120.084
histone methylationGO:0016571600.082
regulation of proteolysisGO:00301622930.079
myeloid cell differentiationGO:00300991170.078
protein catabolic processGO:00301633250.076
nucleosome organizationGO:0034728660.073
histone lysine methylationGO:0034968500.071
ubiquitin dependent protein catabolic processGO:00065112060.070
mitotic cell cycle phase transitionGO:00447721620.069
regulation of mitotic cell cycle phase transitionGO:19019901180.068
cellular macromolecule catabolic processGO:00442653800.068
nucleosome assemblyGO:0006334500.067
post embryonic developmentGO:000979120.066
modification dependent protein catabolic processGO:00199412090.065
regulation of mitotic cell cycleGO:00073461890.064
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.063
regulation of cellular protein catabolic processGO:1903362960.063
neuroblast proliferationGO:000740540.063
proteolysis involved in cellular protein catabolic processGO:00516032440.063
negative regulation of multicellular organismal processGO:00512413170.061
Rat
negative regulation of myeloid cell differentiationGO:0045638420.061
macromolecule methylationGO:0043414970.061
regulation of cell cycleGO:00517263930.057
protein alkylationGO:0008213740.057
negative regulation of megakaryocyte differentiationGO:0045653160.054
cell cycle checkpointGO:00000751170.053
cellular macromolecular complex assemblyGO:00346223240.051
negative regulation of cellular component organizationGO:00511292350.050
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.050
proteasomal protein catabolic processGO:00104981760.050
mitotic cell cycleGO:00002783260.050
negative regulation of cell cycleGO:00457861930.050
histone acetylationGO:0016573930.048
cell cycle phase transitionGO:00447701730.047
mitotic cell cycle processGO:19030472860.046
chromatin assemblyGO:0031497610.046
peptidyl lysine modificationGO:00182051440.046
immune system developmentGO:00025201950.045
negative regulation of chromosome organizationGO:2001251480.045
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.045
negative regulation of cellular protein metabolic processGO:00322693530.044
negative regulation of developmental processGO:00510932470.044
Rat
protein dna complex subunit organizationGO:0071824800.044
protein processingGO:00164852260.044
protein dna complex assemblyGO:0065004640.043
negative regulation of cellular catabolic processGO:0031330830.043
growthGO:00400072020.042
multicellular organismal agingGO:001025930.042
Worm
regulation of cellular amine metabolic processGO:0033238110.041
regulation of cellular ketone metabolic processGO:0010565500.041
oogenesisGO:004847720.041
protein maturationGO:00516042330.041
nervous system developmentGO:00073992930.038
Rat
negative regulation of organelle organizationGO:00106391260.037
negative regulation of proteolysisGO:00458611320.037
regulation of proteasomal protein catabolic processGO:0061136870.037
ribonucleoside triphosphate catabolic processGO:00092033910.036
ras protein signal transductionGO:0007265730.036
chromatin assembly or disassemblyGO:0006333780.036
negative regulation of cell cycle phase transitionGO:1901988890.035
internal protein amino acid acetylationGO:00064751010.035
cellular amino acid metabolic processGO:00065201160.035
negative regulation of immune system processGO:00026831360.035
ribonucleoside catabolic processGO:00424544060.034
cell projection organizationGO:00300302520.033
regulation of mitosisGO:0007088630.033
negative regulation of protein maturationGO:19033181420.033
purine ribonucleoside metabolic processGO:00461284370.033
protein acetylationGO:00064731160.032
regulation of protein catabolic processGO:00421761550.032
dna conformation changeGO:00711031130.032
cell divisionGO:00513011680.032
positive regulation of developmental processGO:00510943140.031
Rat
regulation of chromosome segregationGO:0051983440.031
negative regulation of cell cycle processGO:00109481210.031
determination of adult lifespanGO:000834020.031
Worm
dna packagingGO:0006323770.031
regulation of cell cycle phase transitionGO:19019871260.031
regulation of protein maturationGO:19033171500.030
negative regulation of mitotic cell cycle phase transitionGO:1901991850.030
female gamete generationGO:000729220.029
locomotory behaviorGO:000762610.029
regulation of myeloid cell differentiationGO:0045637810.029
negative regulation of mitotic cell cycleGO:00459301020.029
negative regulation of catabolic processGO:00098951040.029
mitotic cell cycle checkpointGO:0007093680.029
purine ribonucleoside catabolic processGO:00461303980.027
organophosphate catabolic processGO:00464344300.027
cellular protein catabolic processGO:00442572610.027
protein modification by small protein conjugationGO:00324463420.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
nucleoside phosphate catabolic processGO:19012924120.027
histone h4 acetylationGO:0043967470.027
protein ubiquitinationGO:00165673140.026
cellular lipid metabolic processGO:00442553030.026
Yeast
positive regulation of cellular amino acid metabolic processGO:004576430.026
epithelial cell proliferationGO:00506731280.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
small gtpase mediated signal transductionGO:0007264780.026
negative regulation of protein processingGO:00109551420.025
nucleotide catabolic processGO:00091664080.025
lipid metabolic processGO:00066293810.025
Yeast
cellular component morphogenesisGO:00329893140.025
negative regulation of cellular protein catabolic processGO:1903363380.025
memoryGO:000761330.025
chromosome segregationGO:00070591140.025
regulation of protein processingGO:00706131500.025
nucleoside triphosphate metabolic processGO:00091414220.025
regulation of sister chromatid segregationGO:0033045270.025
carbohydrate metabolic processGO:00059752070.024
nucleoside catabolic processGO:00091644080.024
reproductive processGO:00224141060.024
glycosyl compound catabolic processGO:19016584130.024
negative regulation of intracellular signal transductionGO:19025321830.024
positive regulation of cell proliferationGO:00082843010.024
Human
positive regulation of catabolic processGO:00098963100.024
negative regulation of phosphorus metabolic processGO:00105632670.024
negative regulation of phosphate metabolic processGO:00459362670.024
purine containing compound catabolic processGO:00725234110.023
regulation of nuclear divisionGO:0051783650.023
hematopoietic or lymphoid organ developmentGO:00485341860.023
morphogenesis of embryonic epitheliumGO:001633140.023
positive regulation of hydrolase activityGO:00513453310.023
thalamus developmentGO:002179420.023
purine nucleotide catabolic processGO:00061954050.023
response to oxygen containing compoundGO:19017003690.023
segmentationGO:003528240.023
negative regulation of catalytic activityGO:00430863350.023
developmental process involved in reproductionGO:0003006660.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
negative regulation of protein catabolic processGO:0042177590.022
ribonucleotide catabolic processGO:00092614050.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
cellular ketone metabolic processGO:0042180800.022
mitotic sister chromatid separationGO:0051306180.022
negative regulation of cell proliferationGO:00082852280.022
monocarboxylic acid metabolic processGO:00327871850.022
sister chromatid segregationGO:0000819540.022
adult locomotory behaviorGO:000834410.022
neuromuscular junction developmentGO:000752830.022
cytoplasmic transportGO:00164823790.022
megakaryocyte differentiationGO:0030219250.021
nucleoside triphosphate catabolic processGO:00091433940.021
single organism cellular localizationGO:19025803320.021
regulation of hematopoietic progenitor cell differentiationGO:1901532240.021
cell morphogenesisGO:00009022960.021
negative regulation of protein metabolic processGO:00512483910.021
single organism carbohydrate metabolic processGO:00447231930.021
regenerationGO:003109940.021
single organism reproductive processGO:0044702980.021
purine ribonucleotide catabolic processGO:00091544040.021
negative regulation of proteasomal protein catabolic processGO:1901799320.020
regulation of cellular response to stressGO:00801352440.020
regulation of chromosome organizationGO:00330441030.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.020
response to cytokineGO:00340972320.020
mitotic nuclear divisionGO:00070671190.020
maintenance of locationGO:00512351120.020
hematopoietic progenitor cell differentiationGO:0002244380.020
protein localization to organelleGO:00333652800.020
regulation of nucleotide metabolic processGO:00061402690.019
regulation of metaphase anaphase transition of cell cycleGO:1902099260.019
negative regulation of cell differentiationGO:00455961710.019
Rat
peripheral nervous system developmentGO:000742220.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
purine nucleoside catabolic processGO:00061523980.019
hindbrain developmentGO:003090230.019
hemopoiesisGO:00300971800.019
positive regulation of cellular catabolic processGO:00313312840.019
regulation of cell divisionGO:00513021160.019
system processGO:00030083490.019
Mouse
primary neural tube formationGO:001402030.019
cell developmentGO:00484683280.019
Rat
rho protein signal transductionGO:0007266260.019
neurogenesisGO:00220081690.019
Rat
photoreceptor cell differentiationGO:004653020.018
neural tube formationGO:000184130.018
blastoderm segmentationGO:000735020.018
negative regulation of cellular amine metabolic processGO:003323930.018
neuron differentiationGO:00301821380.018
Rat
amine metabolic processGO:0009308440.018
regulation of purine nucleotide metabolic processGO:19005422640.018
epithelium developmentGO:00604292270.018
associative learningGO:000830610.018
regulation of anatomical structure morphogenesisGO:00226032860.018
protein deubiquitinationGO:0016579790.017
positive regulation of cell deathGO:00109422630.017
regulation of growthGO:00400081650.017
gene silencingGO:0016458490.017
regulation of mitotic metaphase anaphase transitionGO:0030071260.017
regulation of epithelial cell proliferationGO:00506781130.017
guanosine containing compound metabolic processGO:19010682440.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
negative regulation of hematopoietic progenitor cell differentiationGO:1901533180.017
regulation of nucleotide catabolic processGO:00308112050.017
regulation of protein localizationGO:00328802960.017
regulation of mitotic sister chromatid separationGO:0010965270.017
regulation of purine nucleotide catabolic processGO:00331212050.016
positive regulation of transportGO:00510503360.016
regulation of establishment of protein localizationGO:00702012420.016
nucleocytoplasmic transportGO:00069131760.016
regulation of intracellular transportGO:00323861950.016
regulation of cellular component movementGO:00512703340.016
nerve developmentGO:002167540.016
protein targetingGO:00066051870.016
single organism membrane organizationGO:00448022680.016
spindle checkpointGO:0031577260.016
embryonic epithelial tube formationGO:000183840.016
negative regulation of cell deathGO:00605483450.016
Rat
spermatid differentiationGO:004851540.016
mitotic sister chromatid segregationGO:0000070530.016
cell growthGO:00160491600.016
metaphase anaphase transition of cell cycleGO:0044784210.016
regulation of mitotic sister chromatid segregationGO:0033047270.016
regulation of transferase activityGO:00513383550.016
cation transportGO:00068123310.016
circadian behaviorGO:004851220.015
dephosphorylationGO:00163112090.015
positive regulation of cell growthGO:0030307480.015
regulation of cellular component biogenesisGO:00440872810.015
innate immune responseGO:00450871780.015
regulation of dna metabolic processGO:00510521530.015
intracellular protein transportGO:00068862700.015
motor neuron axon guidanceGO:000804520.015
regulation of mapk cascadeGO:00434082620.015
generation of neuronsGO:00486991520.015
Rat
gtp metabolic processGO:00460392390.015
nitrogen compound transportGO:00717051910.015
gtp catabolic processGO:00061842370.015
regulation of cell migrationGO:00303342890.015
regulation of neural precursor cell proliferationGO:200017740.015
positive regulation of organelle organizationGO:00106381950.015
neurological system processGO:00508771630.015
positive regulation of programmed cell deathGO:00430682490.015
rna processingGO:00063962550.015
positive regulation of apoptotic processGO:00430652460.015
regulation of protein transportGO:00512232130.015
negative regulation of phosphorylationGO:00423261740.015
chemical homeostasisGO:00488783060.015
rhythmic behaviorGO:000762220.015
regulation of gene silencingGO:0060968240.015
posttranscriptional regulation of gene expressionGO:00106082130.015
internal peptidyl lysine acetylationGO:0018393970.015
organ formationGO:004864530.015
nuclear transportGO:00511691790.015
negative regulation of hydrolase activityGO:00513461820.015
multi organism reproductive processGO:0044703540.015
double strand break repairGO:00063021010.015
regulation of ras protein signal transductionGO:00465781550.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
regulation of cellular amino acid metabolic processGO:000652160.015
regulation of gtpase activityGO:00430871800.014
positive regulation of nucleoside metabolic processGO:00459791860.014
methylationGO:00322591060.014
regulation of locomotionGO:00400123290.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
cell part morphogenesisGO:00329901370.014
endomembrane system organizationGO:00102561960.014
cellular amine metabolic processGO:0044106410.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
protein modification by small protein removalGO:0070646920.014
vesicle mediated transportGO:00161923710.014
signal transduction by phosphorylationGO:00230142970.014
protein localization to membraneGO:00726571600.014
anterior posterior axis specificationGO:000994820.014
spermatid developmentGO:000728640.014
positive regulation of cellular component organizationGO:00511303760.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
oxidation reduction processGO:00551143960.014
regulation of nucleoside metabolic processGO:00091182090.014
establishment of protein localization to organelleGO:00725941720.014
cell fate determinationGO:000170930.014
reactive oxygen species biosynthetic processGO:190340940.014
i kappab kinase nf kappab signalingGO:00072491660.014
regulation of protein ubiquitinationGO:0031396950.014
organelle assemblyGO:00709251760.014
negative regulation of programmed cell deathGO:00430693210.014
recombinational repairGO:0000725500.014
membrane organizationGO:00610242920.014
anterior posterior axis specification embryoGO:000859520.014
apoptotic signaling pathwayGO:00971902680.014
immune responseGO:00069553070.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
tripartite regional subdivisionGO:000735120.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
actin filament based processGO:00300292240.014
small molecule biosynthetic processGO:00442831570.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
regulation of cell growthGO:00015581350.014
negative regulation of protein modification processGO:00314002000.014
guanosine containing compound catabolic processGO:19010692390.014
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
inner ear morphogenesisGO:004247240.013
neural tube closureGO:000184330.013
embryo developmentGO:00097901230.013
cell adhesionGO:00071553250.013
oocyte developmentGO:004859910.013
regulation of cell morphogenesisGO:00226041530.013
microtubule based processGO:00070172100.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
positive regulation of phosphorylationGO:00423273940.013
reproductionGO:0000003630.013
nuclear divisionGO:00002801280.013
limbic system developmentGO:002176130.013
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.013
biological adhesionGO:00226103310.013
regulation of response to external stimulusGO:00321012220.013
regulation of kinase activityGO:00435493140.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
positive regulation of nucleotide catabolic processGO:00308131850.013
cellular response to cytokine stimulusGO:00713451810.013
establishment of planar polarityGO:000173630.013
glycerolipid metabolic processGO:00464861070.013
transmembrane transportGO:00550853990.013
cd4 positive alpha beta t cell differentiationGO:004336740.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
regulation of protein kinase activityGO:00458592890.013
mapk cascadeGO:00001652880.013
compound eye developmentGO:004874910.013
morphogenesis of a polarized epitheliumGO:000173830.012
ion transmembrane transportGO:00342203380.012
negative regulation of mitosisGO:0045839240.012
viral life cycleGO:00190581320.012
fatty acid metabolic processGO:00066311150.012
tube closureGO:006060630.012
response to abiotic stimulusGO:00096283360.012
secretion by cellGO:00329402260.012
cell projection morphogenesisGO:00488581290.012
regulation of cell motilityGO:20001452990.012
positive regulation of cell differentiationGO:00455972110.012
Rat
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
double strand break repair via homologous recombinationGO:0000724500.012
mitotic spindle checkpointGO:0071174180.012
organelle fissionGO:00482851490.012
negative regulation of gliogenesisGO:001401430.012
Rat
regulation of endopeptidase activityGO:00525481700.012
positive regulation of cellular component movementGO:00512721810.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
reactive nitrogen species metabolic processGO:200105730.012
visual behaviorGO:000763220.012
cation transmembrane transportGO:00986552380.012
regulation of gene expression epigeneticGO:0040029730.012
regulation of multi organism processGO:00439001570.012
regulation of cell developmentGO:00602841610.012
Rat
anion transportGO:00068201610.012
positive regulation of gtp catabolic processGO:00331261660.012
demethylationGO:0070988370.012
reactive oxygen species metabolic processGO:0072593750.012
regulation of gtp catabolic processGO:00331241800.012
salivary gland morphogenesisGO:000743540.012
response to axon injuryGO:004867810.012
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.011
regulation of cytokine productionGO:00018172320.011
regulation of meiotic cell cycleGO:005144540.011
cardiac muscle cell contractionGO:008600340.011
anatomical structure homeostasisGO:00602491000.011
nuclear importGO:00511701060.011
regulation of immune responseGO:00507762010.011
microtubule cytoskeleton organizationGO:00002261760.011
positive regulation of nucleotide metabolic processGO:00459812300.011
dna integrity checkpointGO:0031570710.011
cellular response to endogenous stimulusGO:00714953360.011
forebrain generation of neuronsGO:002187230.011
behaviorGO:00076101120.011
multi organism cellular processGO:00447641560.011
Yeast
positive regulation of gtpase activityGO:00435471660.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
tissue regenerationGO:004224630.011
carboxylic acid biosynthetic processGO:0046394970.011
carbohydrate derivative biosynthetic processGO:19011372070.011
metal ion transportGO:00300012720.011
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.011
sensory perception of painGO:001923340.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
positive regulation of synaptic transmissionGO:005080640.011
regulation of response to dna damage stimulusGO:2001020940.011
regulation of secretion by cellGO:19035301770.011
rna interferenceGO:001624640.011
cerebellum developmentGO:002154920.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
protein autophosphorylationGO:00467771230.011
cellular protein complex assemblyGO:00436231880.011
negative regulation of apoptotic processGO:00430663160.011
interspecies interaction between organismsGO:00444191560.011
defense responseGO:00069523150.011
thymus developmentGO:004853830.011
forebrain neuron differentiationGO:002187930.011
regulation of secretionGO:00510461940.011
organophosphate biosynthetic processGO:00904071630.011
Yeast
oocyte differentiationGO:000999420.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
cell projection assemblyGO:00300311260.011
sequestering of metal ionGO:0051238240.011
neuron projection developmentGO:00311751060.011
positive regulation of proteolysisGO:00458621420.011
circulatory system developmentGO:00723592620.011
cation homeostasisGO:00550801890.011
positive regulation of transferase activityGO:00513472270.011
spinal cord developmentGO:002151040.011
monosaccharide metabolic processGO:0005996740.011
regulation of bindingGO:00510981110.011
cellular response to abiotic stimulusGO:00712141170.011
syncytium formation by plasma membrane fusionGO:000076820.011
regulation of cell projection organizationGO:00313441070.010
matingGO:000761810.010
regulation of peptidase activityGO:00525471800.010
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.010
protein oligomerizationGO:00512591730.010
nucleus localizationGO:005164710.010
sexual reproductionGO:0019953370.010
organic acid biosynthetic processGO:0016053970.010
actin mediated cell contractionGO:0070252120.010
response to nitrogen compoundGO:19016981840.010
neurotransmitter secretionGO:000726940.010
spindle assembly checkpointGO:0071173170.010
mitochondrion organizationGO:00070051560.010
cellular response to external stimulusGO:00714961110.010
neuron remodelingGO:001632220.010
cell morphogenesis involved in differentiationGO:00009041440.010
positive regulation of kinase activityGO:00336742040.010
positive regulation of immune system processGO:00026842830.010
cellular homeostasisGO:00197251960.010
positive regulation of protein kinase activityGO:00458601900.010
organic hydroxy compound metabolic processGO:19016151470.010
cellular response to oxygen containing compoundGO:19017012760.010
positive regulation of protein phosphorylationGO:00019343130.010
lipid catabolic processGO:0016042840.010
endosomal transportGO:00161971290.010
skeletal system developmentGO:0001501790.010
metaphase anaphase transition of mitotic cell cycleGO:0007091210.010

KDM4A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.029
musculoskeletal system diseaseDOID:172230.024
inherited metabolic disorderDOID:6552420.022
central nervous system diseaseDOID:3311860.020
nervous system diseaseDOID:8634310.020
disease of cellular proliferationDOID:145661740.018
organ system cancerDOID:00506861640.018
cancerDOID:1621670.018
sensory system diseaseDOID:00501552030.018
eye and adnexa diseaseDOID:14921500.015
eye diseaseDOID:56141490.015
bone diseaseDOID:0080001880.014
connective tissue diseaseDOID:651090.014
retinal diseaseDOID:56791180.013
immune system diseaseDOID:29141550.013
muscular diseaseDOID:00800001140.013
muscle tissue diseaseDOID:661130.013
myopathyDOID:4231040.012
neurodegenerative diseaseDOID:12891020.012
brain diseaseDOID:936730.011
retinal degenerationDOID:8466890.011