Homo sapiens

53 known processes

ITM2B

integral membrane protein 2B

(Aliases: E25B,BRICD2B,BRI2,BRI,FBD,E3-16,ABRI)

ITM2B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of natural killer cell mediated cytotoxicityGO:0042269160.495
detection of chemical stimulus involved in sensory perceptionGO:0050907330.457
positive regulation of exocytosisGO:0045921350.410
negative regulation of multicellular organismal processGO:00512413170.370
Human
positive regulation of natural killer cell mediated immunityGO:0002717120.279
regulation of innate immune responseGO:0045088970.275
positive regulation of innate immune responseGO:0045089790.255
positive regulation of natural killer cell activationGO:003281680.221
regulation of leukocyte mediated immunityGO:0002703380.217
positive regulation of lymphocyte mediated immunityGO:0002708230.199
leukocyte activationGO:00453211640.175
defense responseGO:00069523150.169
innate immune responseGO:00450871780.166
positive regulation of leukocyte degranulationGO:004330230.162
signal transduction by phosphorylationGO:00230142970.161
positive regulation of immune system processGO:00026842830.148
regulation of hormone levelsGO:00108171250.145
leukocyte mediated immunityGO:0002443590.131
protein localization to organelleGO:00333652800.128
cell killingGO:0001906340.128
antigen processing and presentation via mhc class ibGO:000247530.128
regulation of cytokine productionGO:00018172320.126
apoptotic signaling pathwayGO:00971902680.125
Mouse
cytokine productionGO:00018162470.118
granzyme mediated apoptotic signaling pathwayGO:000862640.113
natural killer cell mediated immunityGO:0002228230.111
positive regulation of secretion by cellGO:19035321080.109
positive regulation of immune responseGO:00507781590.107
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.104
regulation of defense responseGO:00313471540.102
regulation of leukocyte activationGO:00026941150.100
immune responseGO:00069553070.096
mapk cascadeGO:00001652880.096
positive regulation of immune effector processGO:0002699400.096
protein processingGO:00164852260.089
cellular amide metabolic processGO:0043603690.085
regulation of protein localizationGO:00328802960.085
natural killer cell mediated cytotoxicityGO:0042267230.082
regulation of mapk cascadeGO:00434082620.080
protein modification by small protein conjugationGO:00324463420.075
regulation of cell differentiationGO:00455953930.075
Human
post embryonic developmentGO:000979120.073
cell activationGO:00017752130.073
positive regulation of leukocyte mediated immunityGO:0002705240.073
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.072
regulation of cell killingGO:0031341220.071
regulation of lymphocyte mediated immunityGO:0002706330.070
cellular protein catabolic processGO:00442572610.069
regulation of exocytosisGO:0017157460.068
cellular homeostasisGO:00197251960.066
regulation of leukocyte mediated cytotoxicityGO:0001910190.065
negative regulation of glycoprotein metabolic processGO:190301980.062
regulation of intracellular transportGO:00323861950.061
post golgi vesicle mediated transportGO:0006892360.061
positive regulation of cellular catabolic processGO:00313312840.058
determination of adult lifespanGO:000834020.057
negative regulation of developmental processGO:00510932470.057
Human
immune effector processGO:00022521590.057
lymphocyte activationGO:00466491330.056
actin polymerization or depolymerizationGO:0008154560.056
lymphocyte mediated immunityGO:0002449480.055
cellular component disassemblyGO:0022411920.055
circulatory system developmentGO:00723592620.054
regulation of secretionGO:00510461940.053
hormone metabolic processGO:0042445610.053
regulation of cell activationGO:00508651250.051
system processGO:00030083490.049
blood vessel morphogenesisGO:00485141620.048
regulation of purine nucleotide metabolic processGO:19005422640.048
natural killer cell degranulationGO:004332020.048
negative regulation of protein metabolic processGO:00512483910.047
negative regulation of cellular protein metabolic processGO:00322693530.047
positive regulation of leukocyte mediated cytotoxicityGO:0001912160.047
regulation of immune responseGO:00507762010.047
regulation of protein maturationGO:19033171500.046
positive regulation of transportGO:00510503360.046
purine nucleoside triphosphate metabolic processGO:00091444120.046
regulation of cellular component movementGO:00512703340.045
regulation of lymphocyte activationGO:00512491030.045
regulation of glycoprotein metabolic processGO:1903018190.044
phospholipid translocationGO:004533220.044
positive regulation of catabolic processGO:00098963100.043
chemical homeostasisGO:00488783060.043
metal ion transportGO:00300012720.043
regulation of natural killer cell mediated immunityGO:0002715160.042
peptide metabolic processGO:0006518510.042
protein ubiquitinationGO:00165673140.041
proteolysis involved in cellular protein catabolic processGO:00516032440.041
intracellular protein transportGO:00068862700.041
actin filament based processGO:00300292240.040
cytoplasmic transportGO:00164823790.039
positive regulation of cell proliferationGO:00082843010.039
long term memoryGO:000761620.039
positive regulation of cell killingGO:0031343190.038
positive regulation of leukocyte activationGO:0002696800.037
regulation of cytoskeleton organizationGO:00514931770.037
posttranscriptional regulation of gene expressionGO:00106082130.037
cellular amino acid metabolic processGO:00065201160.036
regulation of peptidase activityGO:00525471800.036
wnt signaling pathwayGO:00160551560.036
sensory perception of tasteGO:0050909360.036
protein catabolic processGO:00301633250.036
negative regulation of cell proliferationGO:00082852280.035
regulation of immune effector processGO:0002697910.035
negative regulation of protein processingGO:00109551420.034
regulation of protein catabolic processGO:00421761550.034
regulation of protein stabilityGO:0031647870.034
rho protein signal transductionGO:0007266260.034
positive regulation of t cell tolerance inductionGO:000266620.033
exocytosisGO:0006887710.033
detection of chemical stimulusGO:0009593550.033
microtubule based processGO:00070172100.033
protein complex disassemblyGO:0043241520.032
regulation of leukocyte differentiationGO:1902105610.032
regulation of cell migrationGO:00303342890.032
nucleoside triphosphate catabolic processGO:00091433940.032
negative regulation of intracellular signal transductionGO:19025321830.031
endocrine processGO:0050886250.031
cell adhesionGO:00071553250.031
protein refoldingGO:0042026140.030
negative regulation of cell deathGO:00605483450.030
actin cytoskeleton organizationGO:00300362070.030
organelle fusionGO:0048284360.029
negative regulation of catalytic activityGO:00430863350.029
positive regulation of nucleotide catabolic processGO:00308131850.029
positive regulation of gtpase activityGO:00435471660.029
cellular protein complex disassemblyGO:0043624360.029
golgi to vacuole transportGO:000689630.029
positive regulation of lymphocyte activationGO:0051251730.028
response to bacteriumGO:00096171440.028
small gtpase mediated signal transductionGO:0007264780.028
regulation of cellular amino acid metabolic processGO:000652160.028
cation transportGO:00068123310.028
response to external biotic stimulusGO:00432072610.028
metal ion homeostasisGO:00550651690.027
regulation of cell cycleGO:00517263930.027
leukocyte mediated cytotoxicityGO:0001909270.027
adaptive immune responseGO:0002250490.027
protein stabilizationGO:0050821640.027
transforming growth factor beta productionGO:0071604140.027
epithelium migrationGO:00901321190.027
cation homeostasisGO:00550801890.026
single organism membrane organizationGO:00448022680.026
transforming growth factor beta1 productionGO:003290530.026
non canonical wnt signaling pathwayGO:0035567140.026
positive regulation of cytokine productionGO:00018191670.026
positive regulation of cell differentiationGO:00455972110.026
protein maturationGO:00516042330.026
leukocyte activation involved in immune responseGO:0002366300.026
regulation of systemic arterial blood pressure by hormoneGO:0001990120.026
positive regulation of phosphorylationGO:00423273940.026
anatomical structure homeostasisGO:00602491000.026
enzyme linked receptor protein signaling pathwayGO:00071673030.026
positive regulation of hydrolase activityGO:00513453310.026
positive regulation of cellular component organizationGO:00511303760.026
negative regulation of locomotionGO:00400131180.025
immune system developmentGO:00025201950.025
locomotory behaviorGO:000762610.025
negative regulation of apoptotic processGO:00430663160.025
memoryGO:000761330.025
angiogenesisGO:00015251470.025
positive regulation of cell activationGO:0050867810.024
cellular macromolecule catabolic processGO:00442653800.024
ribonucleotide catabolic processGO:00092614050.024
regulation of actin cytoskeleton organizationGO:00329561160.024
regulated secretory pathwayGO:0045055200.024
lysosomal transportGO:0007041330.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
negative regulation of transportGO:00510511760.023
cellular response to fibroblast growth factor stimulusGO:0044344390.023
hemopoiesisGO:00300971800.023
purine ribonucleoside metabolic processGO:00461284370.023
negative regulation of cell cycleGO:00457861930.022
positive regulation of secretionGO:00510471160.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
establishment of planar polarityGO:000173630.022
cellular ketone metabolic processGO:0042180800.022
response to inorganic substanceGO:00100351270.022
organophosphate catabolic processGO:00464344300.022
negative regulation of immune system processGO:00026831360.022
positive regulation of regulatory t cell differentiationGO:004559130.022
regulation of establishment of protein localizationGO:00702012420.022
cellular response to growth factor stimulusGO:00713631970.022
negative regulation of catabolic processGO:00098951040.022
regulation of natural killer cell activationGO:003281490.022
eye pigmentationGO:004806910.021
positive regulation of nucleoside metabolic processGO:00459791860.021
macromolecular complex disassemblyGO:0032984600.021
response to hormoneGO:00097251750.021
regulation of proteolysisGO:00301622930.021
biological adhesionGO:00226103310.021
endosomal transportGO:00161971290.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
secretion by cellGO:00329402260.021
cardiovascular system developmentGO:00723582620.021
regulation of cellular response to stressGO:00801352440.021
cellular metal ion homeostasisGO:00068751460.020
regulation of actin filament based processGO:00329701410.020
regulation of gtp catabolic processGO:00331241800.020
positive regulation of mapk cascadeGO:00434101900.020
sensory perception of chemical stimulusGO:0007606380.020
regulation of anatomical structure morphogenesisGO:00226032860.020
response to other organismGO:00517072610.020
regulation of ion transportGO:00432691890.020
blood vessel endothelial cell migrationGO:0043534420.020
positive regulation of wnt signaling pathwayGO:0030177540.020
regulation of regulated secretory pathwayGO:1903305100.020
regulation of endopeptidase activityGO:00525481700.020
cellular hormone metabolic processGO:0034754410.019
negative regulation of vasculature developmentGO:1901343430.019
regulation of ras gtpase activityGO:00323181280.019
negative regulation of b cell mediated immunityGO:000271330.019
prostate gland developmentGO:003085030.019
regulation of secretion by cellGO:19035301770.019
regulation of anatomical structure sizeGO:00900661010.019
t cell differentiation in thymusGO:003307740.019
protein depolymerizationGO:0051261300.019
regulation of multi organism processGO:00439001570.019
negative regulation of programmed cell deathGO:00430693210.018
positive regulation of rho gtpase activityGO:0032321560.018
response to biotic stimulusGO:00096072760.018
detection of stimulusGO:0051606850.018
response to woundingGO:00096111680.018
regulation of transforming growth factor beta1 productionGO:003290830.018
hematopoietic or lymphoid organ developmentGO:00485341860.018
ras protein signal transductionGO:0007265730.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.017
regulation of transferase activityGO:00513383550.017
regulation of nucleotide metabolic processGO:00061402690.017
negative regulation of protein maturationGO:19033181420.017
regulation of organelle transport along microtubuleGO:190251320.017
transition metal ion transportGO:0000041230.017
oogenesisGO:004847720.017
regulation of angiotensin levels in bloodGO:000200230.017
regulation of angiotensin metabolic processGO:006017730.017
cell growthGO:00160491600.017
regulation of actin polymerization or depolymerizationGO:0008064560.017
cholesterol transportGO:0030301390.017
regulation of wnt signaling pathwayGO:00301111230.017
regulation of myeloid cell differentiationGO:0045637810.016
peripheral nervous system developmentGO:000742220.016
carbohydrate derivative biosynthetic processGO:19011372070.016
circulatory system processGO:00030131130.016
regulation of microtubule based processGO:0032886740.016
calcium ion homeostasisGO:00550741220.016
regulation of leukocyte proliferationGO:0070663670.016
blood circulationGO:00080151130.016
tissue regenerationGO:004224630.016
leukocyte differentiationGO:0002521980.016
protein localization to membraneGO:00726571600.016
establishment of protein localization to organelleGO:00725941720.016
regulation of rho gtpase activityGO:0032319660.016
negative regulation of hydrolase activityGO:00513461820.016
membrane organizationGO:00610242920.016
regulation of microtubule based movementGO:006063260.016
regulation of t cell activationGO:0050863770.015
regulation of apoptotic signaling pathwayGO:20012331750.015
nerve developmentGO:002167540.015
lipid translocationGO:003420420.015
activation of immune responseGO:00022531140.015
negative regulation of jak stat cascadeGO:004642640.015
positive regulation of nucleotide metabolic processGO:00459812300.015
organic hydroxy compound metabolic processGO:19016151470.015
purine containing compound catabolic processGO:00725234110.015
regulation of bindingGO:00510981110.015
negative regulation of protein transportGO:0051224750.015
divalent inorganic cation homeostasisGO:00725071360.015
multicellular organismal agingGO:001025930.015
meiosis iGO:000712740.015
epithelial cell proliferationGO:00506731280.015
glycoprotein metabolic processGO:00091001100.015
regulation of neuronal synaptic plasticityGO:004816810.015
regulation of gtpase activityGO:00430871800.015
negative regulation of peptidase activityGO:0010466910.014
nucleoside catabolic processGO:00091644080.014
cellular chemical homeostasisGO:00550821800.014
regenerationGO:003109940.014
dendritic cell differentiationGO:0097028130.014
carbohydrate metabolic processGO:00059752070.014
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.014
cellular amine metabolic processGO:0044106410.014
positive regulation of cellular amine metabolic processGO:003324070.014
endomembrane system organizationGO:00102561960.014
myeloid cell differentiationGO:00300991170.014
negative regulation of protein modification processGO:00314002000.013
epithelium developmentGO:00604292270.013
positive regulation of apoptotic processGO:00430652460.013
cellular response to oxygen containing compoundGO:19017012760.013
female gamete generationGO:000729220.013
regulation of t cell proliferationGO:0042129420.013
negative regulation of cellular component organizationGO:00511292350.013
Human
positive regulation of ras gtpase activityGO:00323201170.013
blood vessel developmentGO:00015681720.013
peptide hormone processingGO:001648690.013
negative regulation of cell differentiationGO:00455961710.013
Human
positive regulation of natural killer cell mediated cytotoxicityGO:0045954110.013
natural killer cell activationGO:0030101120.013
cellular response to oxidative stressGO:0034599850.013
transition metal ion homeostasisGO:0055076310.012
engulfment of apoptotic cellGO:004365220.012
regulation of locomotionGO:00400123290.012
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.012
positive regulation of defense responseGO:0031349870.012
cell projection organizationGO:00300302520.012
Human
neurological system processGO:00508771630.012
peptidyl tyrosine modificationGO:00182121700.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
morphogenesis of a polarized epitheliumGO:000173830.012
cellular response to endogenous stimulusGO:00714953360.012
response to oxidative stressGO:00069791210.012
immune response inhibiting cell surface receptor signaling pathwayGO:000276740.012
blastoderm segmentationGO:000735020.012
regulation of protein processingGO:00706131500.012
negative regulation of cell motilityGO:20001461040.012
amine metabolic processGO:0009308440.012
negative regulation of cellular response to growth factor stimulusGO:0090288410.012
positive regulation of leukocyte differentiationGO:1902107370.012
positive regulation of programmed cell deathGO:00430682490.012
positive regulation of synaptic transmissionGO:005080640.012
secretionGO:00469032540.011
positive regulation of autophagyGO:0010508240.011
establishment of protein localization to membraneGO:00901501210.011
cellular response to hormone stimulusGO:00328701250.011
regulation of nucleotide catabolic processGO:00308112050.011
cellular response to abiotic stimulusGO:00712141170.011
divalent inorganic cation transportGO:00725111580.011
regulation of cell cycle processGO:00105642660.011
astrocyte differentiationGO:004870840.011
regulation of myeloid leukocyte differentiationGO:0002761390.011
nuclear transportGO:00511691790.011
positive regulation of protein transportGO:00512221350.011
interspecies interaction between organismsGO:00444191560.011
cellular protein complex assemblyGO:00436231880.011
positive regulation of developmental processGO:00510943140.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
cellular macromolecular complex assemblyGO:00346223240.011
single organism cell adhesionGO:00986021790.011
regulation of cellular amine metabolic processGO:0033238110.011
response to virusGO:00096151260.011
ribonucleoside triphosphate catabolic processGO:00092033910.011
purine nucleoside catabolic processGO:00061523980.011
positive regulation of cell deathGO:00109422630.011
cellular response to glucocorticoid stimulusGO:007138540.011
neuron developmentGO:00486661130.011
Human
positive regulation of cell cycleGO:00457871400.011
negative regulation of proteolysisGO:00458611320.011
epithelial cell differentiationGO:00308551410.011
regulation of autophagyGO:0010506520.011
interferon gamma productionGO:0032609390.011
protein localization to synapseGO:003541820.011
import into cellGO:009865720.011
inflammatory responseGO:0006954790.010
interaction with hostGO:0051701420.010
negative regulation of leukocyte mediated immunityGO:0002704140.010
cell activation involved in immune responseGO:0002263300.010
canonical wnt signaling pathwayGO:00600701160.010
inorganic ion transmembrane transportGO:00986602310.010
vesicle mediated transportGO:00161923710.010
regulation of protein kinase activityGO:00458592890.010
patterning of blood vesselsGO:000156920.010
iron ion homeostasisGO:0055072150.010
actin filament organizationGO:00070151280.010
immune response regulating signaling pathwayGO:0002764970.010
growthGO:00400072020.010
negative regulation of defense responseGO:0031348470.010
thyroid hormone generationGO:000659020.010
cytoskeleton dependent intracellular transportGO:0030705210.010

ITM2B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
lysosomal storage diseaseDOID:3211470.524
disease of metabolismDOID:00146672950.524
inherited metabolic disorderDOID:6552420.524
epilepsy syndromeDOID:1826410.016
nervous system diseaseDOID:8634310.016
central nervous system diseaseDOID:3311860.016
brain diseaseDOID:936730.016
variable age at onset electroclinical syndromeDOID:005070680.016
electroclinical syndromeDOID:0050701320.016
cerebral degenerationDOID:1443160.013
cancerDOID:1621670.012
disease of cellular proliferationDOID:145661740.012
eye and adnexa diseaseDOID:14921500.011
retinal diseaseDOID:56791180.011
sensory system diseaseDOID:00501552030.011
eye diseaseDOID:56141490.011
mucopolysaccharidosisDOID:12798110.011
acquired metabolic diseaseDOID:0060158580.002
amyloidosisDOID:9120100.002
cerebral amyloid angiopathyDOID:924630.000