Homo sapiens

0 known processes

SMAD5

SMAD family member 5

(Aliases: DKFZp781O1323,DWFC,DKFZp781C1895,JV5-1,MADH5)

SMAD5 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152221.000
Mouse
evasion or tolerance of host defensesGO:004441521.000
Human
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512280.994
Human
transforming growth factor beta receptor signaling pathwayGO:0007179760.984
Human Mouse Fly
response to growth factorGO:00708482050.984
Human Mouse Fly
cellular response to transforming growth factor beta stimulusGO:0071560940.981
Human Mouse Fly
regulation of activin receptor signaling pathwayGO:0032925140.978
Human
regulation of pathway restricted smad protein phosphorylationGO:0060393340.973
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.971
Human Zebrafish Mouse Fly
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.969
Human
response to hostGO:007513620.969
Human
protein localization to organelleGO:00333652800.962
Human
transforming growth factor beta productionGO:0071604140.960
Human
negative regulation of pathway restricted smad protein phosphorylationGO:0060394110.960
Human
dissemination or transmission of symbiont from hostGO:004400710.957
avoidance of host defensesGO:004441320.953
Human
response to host defensesGO:005220020.950
Human
response to defenses of other organism involved in symbiotic interactionGO:005217320.947
Human
avoidance of defenses of other organism involved in symbiotic interactionGO:005183220.942
Human
positive regulation of stem cell differentiationGO:2000738290.940
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.937
Human Zebrafish
negative regulation of sodium ion transmembrane transporter activityGO:200065020.935
regulation of mrna export from nucleusGO:001079330.926
cellular response to endogenous stimulusGO:00714953360.923
Human Mouse Fly
regulation of cellular response to growth factor stimulusGO:0090287760.914
Human
determination of left right asymmetry in lateral mesodermGO:000314010.908
Human
lateral mesoderm developmentGO:004836810.903
Human
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.902
Human
modification dependent macromolecule catabolic processGO:00436322120.890
Human
interspecies interaction between organismsGO:00444191560.882
Human
mesodermal cell fate commitmentGO:000171020.879
positive regulation of mesoderm developmentGO:200038220.860
Human
retinal ganglion cell axon guidanceGO:003129020.860
negative regulation of bmp signaling pathwayGO:0030514170.853
Human
cellular response to growth factor stimulusGO:00713631970.844
Human Mouse Fly
development involved in symbiotic interactionGO:004411110.842
positive regulation of osteoblast differentiationGO:0045669230.834
Mouse
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.831
Human
regulation of proteolysisGO:00301622930.819
Human
regulation of nucleocytoplasmic transportGO:0046822980.806
Human
regulation of ketone biosynthetic processGO:001056670.792
zygotic specification of dorsal ventral axisGO:000735220.789
Human
negative regulation of sodium ion transportGO:001076630.785
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190017510.785
Human
ubiquitin dependent endocytosisGO:007008610.785
evasion or tolerance of defenses of other organism involved in symbiotic interactionGO:005183420.779
Human
positive regulation of bmp signaling pathwayGO:003051390.778
Human
regulation of proteasomal protein catabolic processGO:0061136870.776
Human
smad protein complex assemblyGO:0007183120.773
Human
regulation of nodal signaling pathway involved in determination of left right asymmetryGO:190014510.763
Human
regulation of meiotic cell cycleGO:005144540.758
Worm
nuclear transportGO:00511691790.757
Human
positive regulation of transcription factor import into nucleusGO:0042993250.752
Human
modulation by virus of host morphology or physiologyGO:0019048100.747
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.741
Human
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.740
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.734
Human
viral processGO:00160321460.729
Human
endodermal cell fate commitmentGO:000171140.726
Fly
negative regulation of smad protein complex assemblyGO:001099140.723
Human
positive regulation of proteolysisGO:00458621420.710
Human
trna transportGO:005103110.709
endodermal cell differentiationGO:0035987310.699
Fly
interaction with hostGO:0051701420.693
Human
negative regulation of sodium ion transmembrane transportGO:190230620.683
mesenchymal cell developmentGO:0014031500.680
Human
modification dependent protein catabolic processGO:00199412090.670
Human
negative regulation of cellular response to growth factor stimulusGO:0090288410.659
Human
regulation of canonical wnt signaling pathwayGO:0060828880.658
Human
regulation of nodal signaling pathwayGO:190010710.656
Human
neuron differentiationGO:00301821380.652
regulation of protein import into nucleusGO:0042306780.650
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.645
Human
cell cycle arrestGO:0007050710.637
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.636
Human
activin receptor signaling pathwayGO:0032924240.635
Human
positive regulation of nucleocytoplasmic transportGO:0046824540.633
Human
multi organism cellular processGO:00447641560.627
Human
ribosomal large subunit export from nucleusGO:000005530.620
post embryonic developmentGO:000979120.618
Fly
vasculature developmentGO:00019441810.607
Zebrafish
peptidyl threonine modificationGO:0018210450.601
Human
bmp signaling pathwayGO:0030509490.595
Human Zebrafish Mouse Fly
regulation of smad protein complex assemblyGO:001099040.592
Human
osteoblast differentiationGO:0001649920.577
Mouse
regulation of cellular ketone metabolic processGO:0010565500.571
trna export from nucleusGO:000640910.565
endodermal cell fate specificationGO:000171440.558
Fly
endoderm formationGO:0001706330.554
Fly
regulation of cartilage developmentGO:0061035120.551
regulation of mesoderm developmentGO:200038040.546
Human
regulation of cell cycleGO:00517263930.536
Human Worm Fly
regulation of protein localizationGO:00328802960.535
Human
positive regulation of cellular catabolic processGO:00313312840.535
Human
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190022410.527
Human
regulation of transcription factor import into nucleusGO:0042990390.523
Human
cellular ketone metabolic processGO:0042180800.519
positive regulation of wnt signaling pathwayGO:0030177540.515
Human
neurogenesisGO:00220081690.504
mesonephros developmentGO:0001823170.504
Mouse
nervous system developmentGO:00073992930.499
Fly
positive regulation of proteasomal protein catabolic processGO:1901800350.496
Human
proteasomal protein catabolic processGO:00104981760.494
Human
regulation of epithelial to mesenchymal transitionGO:0010717370.486
Human
negative regulation of cell growthGO:0030308830.485
Human
cellular macromolecule catabolic processGO:00442653800.485
Human
common partner smad protein phosphorylationGO:000718230.483
Human
chemotaxisGO:00069351570.482
Fly
response to external biotic stimulusGO:00432072610.478
Human
negative regulation of apoptotic processGO:00430663160.474
Human
positive regulation of developmental processGO:00510943140.471
Human Mouse Worm Fly
negative regulation of ubiquitin protein transferase activityGO:005144480.467
Human
positive regulation of cytoplasmic transportGO:1903651820.460
Human
cellular amine metabolic processGO:0044106410.453
nucleocytoplasmic transportGO:00069131760.446
Human
positive regulation of canonical wnt signaling pathwayGO:0090263330.445
Human
cellular protein catabolic processGO:00442572610.445
Human
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.441
Human
regulation of bmp signaling pathwayGO:0030510270.440
Human Zebrafish
regulation of establishment of protein localizationGO:00702012420.438
Human
skeletal system developmentGO:0001501790.424
Mouse
inorganic ion transmembrane transportGO:00986602310.421
regulation of anatomical structure morphogenesisGO:00226032860.421
Human Zebrafish
regulation of protein transportGO:00512232130.414
Human
regulation of protein catabolic processGO:00421761550.409
Human
positive regulation of catabolic processGO:00098963100.403
Human
mitotic cell cycleGO:00002783260.393
Human Worm Fly
dissemination or transmission of organism from other organism involved in symbiotic interactionGO:005182110.392
positive regulation of intracellular transportGO:00323881040.389
Human
organ morphogenesisGO:00098871470.388
Zebrafish Fly
embryo developmentGO:00097901230.388
Human Zebrafish Fly
positive regulation of transportGO:00510503360.380
Human
epithelium developmentGO:00604292270.379
Zebrafish Mouse Fly
negative regulation of cellular amine metabolic processGO:003323930.375
protein ubiquitinationGO:00165673140.370
Human
adherens junction organizationGO:0034332360.366
Human
monovalent inorganic cation transportGO:00156721280.359
establishment of protein localization to organelleGO:00725941720.357
Human
endosome transport via multivesicular body sorting pathwayGO:003250930.355
negative regulation of cell cycleGO:00457861930.354
Human Worm Fly
kidney epithelium developmentGO:0072073250.354
Mouse
positive regulation of hydrolase activityGO:00513453310.350
Human
regulation of osteoblast differentiationGO:0045667380.343
Mouse
cellular component morphogenesisGO:00329893140.342
Human
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076710.340
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.336
Human
regulation of epithelial cell migrationGO:0010632930.333
sodium ion transmembrane transportGO:0035725590.328
positive regulation of cellular protein catabolic processGO:1903364370.324
Human
regulation of intracellular transportGO:00323861950.313
Human
defense responseGO:00069523150.313
ribonucleoprotein complex biogenesisGO:00226131160.311
growthGO:00400072020.311
Human Worm Fly
cell projection organizationGO:00300302520.308
positive regulation of ossificationGO:0045778320.308
Mouse
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016410.307
Human
transforming growth factor beta2 productionGO:003290660.304
Human
cell fate commitment involved in formation of primary germ layerGO:006079560.299
Fly
regulation of growthGO:00400081650.297
Human Worm Fly
regulation of ligase activityGO:0051340290.293
Human
response to laminar fluid shear stressGO:003461680.289
Human
regulation of multivesicular body sizeGO:001079610.287
polyprenol metabolic processGO:001609330.287
evasion or tolerance of host defenses by virusGO:001904920.286
Human
pathway restricted smad protein phosphorylationGO:0060389380.285
Human
cytokine productionGO:00018162470.282
Human
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076810.282
negative regulation of protein metabolic processGO:00512483910.280
Human
hindbrain developmentGO:003090230.279
amine metabolic processGO:0009308440.278
single organism nuclear importGO:19025931040.277
Human
protein modification by small protein conjugationGO:00324463420.276
Human
endothelium developmentGO:0003158330.276
canonical wnt signaling pathwayGO:00600701160.275
Human
protein catabolic processGO:00301633250.270
Human
inorganic cation transmembrane transportGO:00986621940.269
negative regulation of cellular protein metabolic processGO:00322693530.266
Human
neuromuscular junction developmentGO:000752830.265
Fly
response to transforming growth factor betaGO:0071559940.263
Human Mouse Fly
regulation of mitotic cell cycleGO:00073461890.262
Human Worm Fly
regulation of ribosome biogenesisGO:009006910.256
protein import into nucleusGO:00066061040.256
Human
cytoplasmic transportGO:00164823790.254
Human
positive regulation of cell cycleGO:00457871400.254
Worm
negative regulation of growthGO:0045926970.248
Human
ion homeostasisGO:00508012300.247
ubiquitin dependent protein catabolic processGO:00065112060.246
Human
cell morphogenesisGO:00009022960.246
Human
regulation of cellular amine metabolic processGO:0033238110.245
regulation of intracellular protein transportGO:00331571230.244
Human
receptor catabolic processGO:0032801110.241
response to other organismGO:00517072610.239
Human
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.237
Human
regulation of cellular protein catabolic processGO:1903362960.237
Human
cellular response to bmp stimulusGO:007177380.236
Mouse
negative regulation of cell cycle g1 s phase transitionGO:1902807290.234
Fly
regulation of stem cell differentiationGO:2000736560.232
Human
positive regulation of dendrite morphogenesisGO:005077530.231
negative regulation of mitotic cell cycleGO:00459301020.230
Human Worm Fly
negative regulation of glial cell proliferationGO:006025320.228
chromatin assembly or disassemblyGO:0006333780.225
intracellular protein transportGO:00068862700.224
Human
tube developmentGO:00352951250.222
Zebrafish Mouse Fly
regulation of cell morphogenesis involved in differentiationGO:0010769830.221
Human
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009410.221
Human Zebrafish
cell adhesionGO:00071553250.220
Human
metal ion transportGO:00300012720.217
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.212
Human
polyprenol biosynthetic processGO:001609410.209
rrna containing ribonucleoprotein complex export from nucleusGO:007142840.208
negative regulation of cell differentiationGO:00455961710.207
Fly
potassium ion transportGO:0006813620.207
cell morphogenesis involved in differentiationGO:00009041440.205
Human
wnt signaling pathwayGO:00160551560.204
Human
negative regulation of gliogenesisGO:001401430.203
regulation of neuron differentiationGO:0045664700.200
peptidyl threonine phosphorylationGO:0018107410.199
Human
potassium ion transmembrane transportGO:0071805600.197
somatic stem cell maintenanceGO:003501940.196
Fly
pituitary gland developmentGO:002198320.195
positive regulation of immune responseGO:00507781590.194
gonad developmentGO:0008406340.193
cellular amino acid metabolic processGO:00065201160.190
regulation of transmembrane transporter activityGO:0022898740.186
regulation of cell morphogenesisGO:00226041530.185
Human
single organism cellular localizationGO:19025803320.182
Human
response to woundingGO:00096111680.181
extrinsic apoptotic signaling pathwayGO:00971911190.180
Human
regulation of epithelial cell proliferationGO:00506781130.179
cell proliferation involved in heart valve developmentGO:200079310.176
blastoderm segmentationGO:000735020.176
Fly
positive regulation of protein ubiquitinationGO:0031398530.176
Human
protein targeting to nucleusGO:00447441040.175
Human
protein importGO:00170381300.175
Human
negative regulation of protein ubiquitinationGO:0031397350.173
Human
regulation of cell developmentGO:00602841610.172
Human
regulation of protein targetingGO:1903533910.169
Human
sodium ion transportGO:0006814610.167
adherens junction assemblyGO:0034333340.166
Human
regulation of protein localization to nucleusGO:1900180850.166
Human
positive regulation of mapk cascadeGO:00434101900.164
single organismal cell cell adhesionGO:00163371480.161
Human
regulation of cell differentiationGO:00455953930.157
Human Mouse Fly
mapk cascadeGO:00001652880.157
regulation of peptidyl serine phosphorylationGO:0033135500.154
Human
neuron developmentGO:00486661130.154
regulation of locomotionGO:00400123290.151
stem cell maintenanceGO:0019827190.148
Fly
positive regulation of peptidase activityGO:0010952880.148
Human
cation transmembrane transportGO:00986552380.148
regulation of cytoplasmic transportGO:19036491490.148
Human
regulation of endothelial cell migrationGO:0010594670.147
stem cell differentiationGO:0048863930.146
Human Fly
ion transmembrane transportGO:00342203380.146
negative regulation of protein modification processGO:00314002000.145
Human
peptidyl serine modificationGO:00182091060.144
Human
cell developmentGO:00484683280.143
Human Mouse Fly
immune responseGO:00069553070.142
Human
rna processingGO:00063962550.141
transmission of virusGO:001908910.141
cell part morphogenesisGO:00329901370.141
positive regulation of cellular component organizationGO:00511303760.139
Human Fly
tube morphogenesisGO:0035239950.138
Zebrafish Fly
negative regulation of cell deathGO:00605483450.138
Human
positive regulation of cell differentiationGO:00455972110.138
Human Mouse
positive regulation of mesenchymal stem cell differentiationGO:200074140.137
negative regulation of peptidyl threonine phosphorylationGO:001080160.136
Human
regulation of wnt signaling pathwayGO:00301111230.135
Human
mesenchyme developmentGO:0060485590.135
Human
positive regulation of nucleoside metabolic processGO:00459791860.132
system processGO:00030083490.131
Mouse
nuclear importGO:00511701060.131
Human
regulation of endopeptidase activityGO:00525481700.131
Human
mesonephric epithelium developmentGO:0072163140.130
Mouse
cellular potassium ion transportGO:0071804600.130
bone developmentGO:0060348260.130
Mouse
negative regulation of cellular amino acid metabolic processGO:004576320.129
positive regulation of programmed cell deathGO:00430682490.129
Human
negative regulation of catalytic activityGO:00430863350.129
Human
coenzyme metabolic processGO:0006732650.127
positive regulation of epithelial to mesenchymal transitionGO:0010718220.125
Human
regulation of cytokine productionGO:00018172320.125
Human
regulation of cell cell adhesionGO:0022407570.122
Human
positive regulation of cell cell adhesionGO:0022409220.122
Human
lipid metabolic processGO:00066293810.120
mesenchymal cell differentiationGO:0048762520.119
Human
angiogenesisGO:00015251470.117
sex differentiationGO:0007548450.116
Worm
midbrain developmentGO:0030901450.114
chemical homeostasisGO:00488783060.114
protein targetingGO:00066051870.114
Human
defense response to other organismGO:00985421290.112
sex determinationGO:000753030.112
smad protein signal transductionGO:0060395100.112
Human
negative regulation of mitotic cell cycle phase transitionGO:1901991850.110
Fly
positive regulation of intracellular protein transportGO:0090316760.108
Human
regulation of cysteine type endopeptidase activityGO:20001161270.107
Human
morphogenesis of an epitheliumGO:0002009600.107
Zebrafish Fly
response to sterolGO:0036314140.106
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.105
blood vessel morphogenesisGO:00485141620.105
Zebrafish
regulation of glial cell proliferationGO:006025140.101
positive regulation of cell adhesionGO:0045785840.099
Human
negative regulation of peptidyl serine phosphorylationGO:003313780.098
Human
stem cell divisionGO:001714520.098
Fly
progesterone receptor signaling pathwayGO:005084730.098
regulation of ubiquitin protein transferase activityGO:0051438280.096
Human
protein complex localizationGO:0031503310.096
Human
cofactor metabolic processGO:0051186870.094
modification by symbiont of host morphology or physiologyGO:0044003120.094
Human
nodal signaling pathwayGO:003809250.093
Human
regulation of potassium ion transmembrane transportGO:1901379200.093
response to organic cyclic compoundGO:00140702040.091
Human Mouse
regulation of transforming growth factor beta2 productionGO:003290960.091
Human
regulation of protein ubiquitinationGO:0031396950.090
Human
protein localization to nucleusGO:00345041360.089
Human
reproductionGO:0000003630.089
Mouse Worm Fly
response to bmpGO:007177280.087
Mouse
positive regulation of protein phosphorylationGO:00019343130.085
negative regulation of transcription by competitive promoter bindingGO:001094480.084
Human
regulation of transferase activityGO:00513383550.084
Human
regulation of ossificationGO:0030278580.084
Mouse
modification of morphology or physiology of other organismGO:0035821430.083
Human
stress activated mapk cascadeGO:0051403930.082
neuron projection developmentGO:00311751060.082
transmembrane transportGO:00550853990.081
determination of bilateral symmetryGO:0009855150.080
Human Zebrafish
negative regulation of neurogenesisGO:0050768260.080
regulation of cellular amino acid metabolic processGO:000652160.080
heart developmentGO:0007507950.080
Zebrafish
regulation of sodium ion transportGO:0002028240.080
single organism cell adhesionGO:00986021790.080
Human
regulation of muscle organ developmentGO:0048634270.079
isoprenoid biosynthetic processGO:000829990.078
protein stabilizationGO:0050821640.078
Human
negative regulation of cell developmentGO:0010721480.077
positive regulation of cysteine type endopeptidase activityGO:2001056790.075
Human
cell cell junction organizationGO:0045216690.074
Human
generation of neuronsGO:00486991520.074
regulation of muscle system processGO:0090257530.073
rna splicing via transesterification reactionsGO:0000375900.073
central nervous system developmentGO:00074171230.073
mitotic cell cycle processGO:19030472860.072
Fly
regulation of immune responseGO:00507762010.072
positive regulation of map kinase activityGO:0043406800.071
positive regulation of cell developmentGO:0010720920.070
Human
regulation of membrane potentialGO:0042391950.070
determination of left right symmetryGO:0007368110.069
Human Zebrafish
response to biotic stimulusGO:00096072760.068
Human
epithelial cell proliferationGO:00506731280.068
negative regulation of cell cycle processGO:00109481210.068
Fly
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.067
Human
negative regulation of developmental processGO:00510932470.067
Fly
heart morphogenesisGO:0003007480.067
Zebrafish
regulation of transforming growth factor beta productionGO:0071634130.067
Human
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817380.067
Human
negative regulation of catabolic processGO:00098951040.067
Human
cell junction organizationGO:0034330790.067
Human
development of primary sexual characteristicsGO:0045137350.066
i kappab kinase nf kappab signalingGO:00072491660.065
actin filament based processGO:00300292240.065
positive regulation of protein catabolic processGO:0045732750.062
Human
nuclear exportGO:0051168690.061
negative regulation of programmed cell deathGO:00430693210.060
Human
fat cell differentiationGO:0045444320.060
Human
regulation of cell migrationGO:00303342890.059
regulation of neuron projection developmentGO:0010975570.059
positive regulation of chondrocyte differentiationGO:003233240.058
innate immune responseGO:00450871780.058
regulation of transmembrane transportGO:00347621390.058
regulation of mapk cascadeGO:00434082620.058
organelle localizationGO:0051640840.057
positive regulation of endopeptidase activityGO:0010950840.057
Human
regulation of male gonad developmentGO:200001840.057
protein processingGO:00164852260.057
Human
heart processGO:0003015620.056
Mouse
positive regulation of catenin import into nucleusGO:003541390.056
Human
negative regulation of ligase activityGO:005135280.054
Human
regulation of sodium ion transmembrane transportGO:1902305230.054
natural killer cell activationGO:0030101120.054
protein autophosphorylationGO:00467771230.054
wound healingGO:00420601150.053
negative regulation of protein transportGO:0051224750.053
ribosomal subunit export from nucleusGO:000005440.053
embryonic epithelial tube formationGO:000183840.053
activation of immune responseGO:00022531140.053
specification of symmetryGO:0009799160.052
Human Zebrafish
membrane repolarizationGO:0086009230.050
cation transportGO:00068123310.050
nodal signaling pathway involved in determination of left right asymmetryGO:003810710.050
Human
meiotic chromosome segregationGO:004513240.050
response to alcoholGO:0097305640.050
Human
regulation of developmental growthGO:0048638300.050
Worm Fly
positive regulation of protein serine threonine kinase activityGO:00719021190.050
biological adhesionGO:00226103310.049
Human
positive regulation of transferase activityGO:00513472270.049
peptidyl lysine acetylationGO:00183941010.049
positive regulation of nucleotide catabolic processGO:00308131850.049
ossificationGO:00015031210.049
Mouse
neuron projection morphogenesisGO:0048812500.049
regulation of fatty acid metabolic processGO:0019217240.049
regulation of neurogenesisGO:0050767820.048
positive regulation of jnk cascadeGO:0046330520.048
regulation of chondrocyte differentiationGO:003233090.048
signal transduction in response to dna damageGO:0042770570.048
catenin import into nucleusGO:0035411180.047
Human
regulation of protein stabilityGO:0031647870.047
Human
cardiovascular system developmentGO:00723582620.047
Zebrafish
regulation of i kappab kinase nf kappab signalingGO:00431221620.047
oxidoreduction coenzyme metabolic processGO:0006733190.046
posttranscriptional regulation of gene expressionGO:00106082130.045
Human
regulation of g1 s transition of mitotic cell cycleGO:2000045400.045
Fly
oogenesisGO:004847720.045
Fly
mitochondrion organizationGO:00070051560.045
response to abiotic stimulusGO:00096283360.045
Human
axon developmentGO:0061564340.044
positive regulation of protein transportGO:00512221350.044
Human
spermatid differentiationGO:004851540.044
regulation of transporter activityGO:0032409820.043
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.043
Fly
epithelium migrationGO:00901321190.043
ubiquitin dependent smad protein catabolic processGO:003057940.043
dephosphorylationGO:00163112090.043
regulation of multi organism processGO:00439001570.042
digestive tract morphogenesisGO:0048546560.042
Zebrafish Fly
response to decreased oxygen levelsGO:0036293960.042
Human
vacuolar transportGO:0007034340.042
mesodermal cell fate specificationGO:000750120.042
positive regulation of epithelial cell proliferationGO:0050679650.042
negative regulation of ion transmembrane transporter activityGO:0032413190.041
positive regulation of cell motilityGO:20001471770.041
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.041
Human
cell divisionGO:00513011680.040
Fly
isoprenoid metabolic processGO:0006720390.040
regulation of cell growthGO:00015581350.040
Human
protein oligomerizationGO:00512591730.040
single organism reproductive processGO:0044702980.040
Mouse Fly
immune response activating signal transductionGO:0002757900.040
regulation of protein modification by small protein conjugation or removalGO:19033201070.040
Human
developmental process involved in reproductionGO:0003006660.039
Mouse Worm Fly
anterior posterior axis specificationGO:000994820.039
positive regulation of pathway restricted smad protein phosphorylationGO:0010862220.039
apoptotic signaling pathwayGO:00971902680.039
Human
negative regulation of ion transmembrane transportGO:0034766260.038
cell fate commitmentGO:0045165270.038
Mouse Fly
response to inorganic substanceGO:00100351270.037
reproductive structure developmentGO:0048608550.037
positive regulation of apoptotic processGO:00430652460.037
Human
zymogen activationGO:0031638700.037
Human
epithelial to mesenchymal transitionGO:0001837480.037
Human
ureteric bud developmentGO:0001657130.036
Mouse
response to hypoxiaGO:0001666960.036
Human
organophosphate catabolic processGO:00464344300.036
positive regulation of locomotionGO:00400171860.036
negative regulation of cell cycle phase transitionGO:1901988890.036
Fly
negative regulation of cellular component organizationGO:00511292350.036
Human
positive regulation of cellular component biogenesisGO:00440891580.036
Fly
female gamete generationGO:000729220.036
Fly
cell type specific apoptotic processGO:00972851250.036
rho protein signal transductionGO:0007266260.035
tissue migrationGO:00901301190.035
regulation of ion transmembrane transportGO:00347651320.035
regulation of cell cycle arrestGO:0071156360.035
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:0043162100.034
response to cholesterolGO:0070723110.034
Human
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.034
Human
positive regulation of protein kinase activityGO:00458601900.034
mrna splicing via spliceosomeGO:0000398890.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.033
regulation of catenin import into nucleusGO:0035412180.033
Human
activation of cysteine type endopeptidase activityGO:0097202570.033
Human
gland developmentGO:0048732480.033
cell projection morphogenesisGO:00488581290.033
positive regulation of cytokine productionGO:00018191670.033
urogenital system developmentGO:0001655650.032
Mouse Fly
cell growthGO:00160491600.032
Human
positive regulation of cellular amino acid metabolic processGO:004576430.032
cell junction assemblyGO:0034329670.031
Human
muscle structure developmentGO:0061061980.031
establishment of organelle localizationGO:0051656590.031
regulation of potassium ion transmembrane transporter activityGO:1901016160.031
negative regulation of protein catabolic processGO:0042177590.031
Human
pattern specification processGO:0007389430.030
Human Zebrafish Fly
regulation of ion transmembrane transporter activityGO:0032412720.030
regulation of metal ion transportGO:00109591200.030
negative regulation of multicellular organismal processGO:00512413170.030
cellular macromolecular complex assemblyGO:00346223240.030
Human
negative regulation of defense responseGO:0031348470.030
rna splicingGO:00083801310.029
regulation of peptidase activityGO:00525471800.029
Human
regulation of cell projection organizationGO:00313441070.029
n terminal protein amino acid modificationGO:0031365130.029
muscle contractionGO:0006936730.029
Mouse
circulatory system developmentGO:00723592620.029
Zebrafish

SMAD5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.236
Human
cancerDOID:1621670.236
Human
organ system cancerDOID:00506861640.106
Human
gastrointestinal system cancerDOID:3119520.031
Human