Homo sapiens

62 known processes

APAF1

apoptotic peptidase activating factor 1

(Aliases: CED4,APAF-1,DKFZp781B1145)

APAF1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
trail activated apoptotic signaling pathwayGO:003646240.988
b cell homeostasisGO:000178210.854
positive regulation of macrophage differentiationGO:004565170.775
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.764
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697790.716
cell cycle arrestGO:0007050710.705
regulation of cell cycle arrestGO:0071156360.683
signal transduction involved in dna damage checkpointGO:0072422150.665
cellular response to mechanical stimulusGO:0071260390.664
regulation of peptidase activityGO:00525471800.647
regulation of macrophage differentiationGO:004564990.641
cellular response to glucocorticoid stimulusGO:007138540.624
mitotic g1 s transition checkpointGO:0044819170.617
regulation of proteolysisGO:00301622930.610
limbic system developmentGO:002176130.607
positive regulation of peptidase activityGO:0010952880.601
signal transduction involved in mitotic dna integrity checkpointGO:1902403130.589
positive regulation of cysteine type endopeptidase activityGO:2001056790.585
cellular response to organic cyclic compoundGO:00714071270.582
signal transduction involved in dna integrity checkpointGO:0072401150.574
signal transduction involved in mitotic cell cycle checkpointGO:0072413130.554
protein maturationGO:00516042330.554
positive regulation of proteolysisGO:00458621420.526
regulation of endopeptidase activityGO:00525481700.513
mitotic g1 dna damage checkpointGO:0031571170.484
cellular response to abiotic stimulusGO:00712141170.473
cellular response to dexamethasone stimulusGO:007154910.464
cell cycle phase transitionGO:00447701730.455
signal transduction involved in cell cycle checkpointGO:0072395160.448
signal transduction involved in mitotic g1 dna damage checkpointGO:0072431100.444
cellular response to uvGO:0034644320.443
protein processingGO:00164852260.441
response to biotic stimulusGO:00096072760.438
positive regulation of cell cycle arrestGO:0071158230.436
response to uvGO:0009411730.432
zymogen activationGO:0031638700.422
regulation of cell cycleGO:00517263930.419
response to lipopolysaccharideGO:0032496700.415
response to other organismGO:00517072610.403
positive regulation of myeloid leukocyte differentiationGO:0002763240.399
cellular response to dna damage stimulusGO:00069743790.399
glial cell apoptotic processGO:003434970.398
Fly
positive regulation of immune system processGO:00026842830.385
response to oxygen containing compoundGO:19017003690.380
urogenital system developmentGO:0001655650.373
response to bacteriumGO:00096171440.368
negative regulation of cell deathGO:00605483450.362
response to abiotic stimulusGO:00096283360.359
Fly
activation of cysteine type endopeptidase activityGO:0097202570.353
cellular response to toxic substanceGO:009723740.352
response to inorganic substanceGO:00100351270.351
renal system processGO:0003014250.350
response to external biotic stimulusGO:00432072610.349
response to metal ionGO:0010038840.348
positive regulation of hydrolase activityGO:00513453310.344
positive regulation of neuron apoptotic processGO:004352580.343
extrinsic apoptotic signaling pathwayGO:00971911190.343
dna damage response signal transduction by p53 class mediatorGO:0030330440.339
g1 dna damage checkpointGO:0044783180.337
intrinsic apoptotic signaling pathwayGO:00971931270.337
response to estrogenGO:0043627470.331
response to radiationGO:00093141510.329
Fly
execution phase of apoptosisGO:0097194320.327
Mouse
apoptotic signaling pathwayGO:00971902680.324
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.324
nervous system developmentGO:00073992930.319
Mouse Fly
hemopoiesisGO:00300971800.319
intracellular signal transduction involved in g1 dna damage checkpointGO:1902400100.318
negative regulation of protein phosphorylationGO:00019331400.317
regulation of response to dna damage stimulusGO:2001020940.317
regulation of cell differentiationGO:00455953930.316
Fly
positive regulation of apoptotic processGO:00430652460.316
immune system developmentGO:00025201950.314
regulation of cysteine type endopeptidase activityGO:20001161270.313
response to xenobiotic stimulusGO:0009410300.312
positive regulation of cell cycle processGO:00900681060.312
regulation of cell cycle phase transitionGO:19019871260.310
negative regulation of programmed cell deathGO:00430693210.306
cellular response to corticosteroid stimulusGO:007138450.305
response to mechanical stimulusGO:0009612510.304
positive regulation of cell cycleGO:00457871400.301
regulation of myeloid cell differentiationGO:0045637810.301
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.300
hippocampus developmentGO:002176610.298
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.298
response to estradiolGO:0032355230.297
response to cytokineGO:00340972320.297
regulation of mitotic cell cycle phase transitionGO:19019901180.294
negative regulation of cell cycle g1 s phase transitionGO:1902807290.293
response to molecule of bacterial originGO:0002237820.292
response to organic cyclic compoundGO:00140702040.289
negative regulation of cell cycleGO:00457861930.287
cellular response to oxygen containing compoundGO:19017012760.286
negative regulation of apoptotic processGO:00430663160.281
cellular response to lipidGO:00713961270.279
regulation of cell cycle processGO:00105642660.278
positive regulation of developmental processGO:00510943140.276
Fly
positive regulation of myeloid cell differentiationGO:0045639390.273
g1 s transition of mitotic cell cycleGO:0000082780.270
cell type specific apoptotic processGO:00972851250.270
Mouse Fly
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.268
erythrocyte differentiationGO:0030218280.268
regulation of i kappab kinase nf kappab signalingGO:00431221620.268
signal transduction in response to dna damageGO:0042770570.266
mitotic cell cycle checkpointGO:0007093680.266
positive regulation of programmed cell deathGO:00430682490.265
cellular response to external stimulusGO:00714961110.264
cellular macromolecule catabolic processGO:00442653800.262
Mouse
dna damage checkpointGO:0000077680.262
cellular response to endogenous stimulusGO:00714953360.260
myeloid cell differentiationGO:00300991170.254
mitotic dna integrity checkpointGO:0044774300.253
renal system developmentGO:0072001630.249
cell death in response to oxidative stressGO:0036473290.247
mitotic cell cycle processGO:19030472860.246
response to tumor necrosis factorGO:0034612760.244
positive regulation of cell differentiationGO:00455972110.242
Fly
mitotic dna damage checkpointGO:0044773280.241
negative regulation of cell cycle phase transitionGO:1901988890.241
i kappab kinase nf kappab signalingGO:00072491660.239
regulation of cell cycle g1 s phase transitionGO:1902806420.232
erythrocyte homeostasisGO:0034101310.229
regulation of mitotic cell cycleGO:00073461890.225
cellular response to oxidative stressGO:0034599850.224
negative regulation of mitotic cell cycleGO:00459301020.224
response to decreased oxygen levelsGO:0036293960.221
protein catabolic processGO:00301633250.220
proteolysis involved in cellular protein catabolic processGO:00516032440.209
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.208
mitotic cell cycle phase transitionGO:00447721620.207
cell cycle checkpointGO:00000751170.206
response to lipidGO:00339932060.205
dna integrity checkpointGO:0031570710.205
myeloid cell homeostasisGO:0002262340.203
substantia nigra developmentGO:0021762450.201
response to cobalt ionGO:003202510.199
negative regulation of cellular protein metabolic processGO:00322693530.198
hematopoietic or lymphoid organ developmentGO:00485341860.196
midbrain developmentGO:0030901450.193
response to dexamethasoneGO:007154810.189
neural nucleus developmentGO:0048857470.189
cellular response to alcoholGO:0097306290.185
cellular response to antibioticGO:007123610.183
negative regulation of cell cycle processGO:00109481210.182
response to steroid hormoneGO:0048545800.177
system processGO:00030083490.175
negative regulation of phosphorus metabolic processGO:00105632670.173
response to hormoneGO:00097251750.172
mitotic cell cycleGO:00002783260.171
circulatory system developmentGO:00723592620.171
response to woundingGO:00096111680.169
cellular response to hormone stimulusGO:00328701250.168
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.168
response to light stimulusGO:0009416870.166
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.166
negative regulation of mitotic cell cycle phase transitionGO:1901991850.166
regulation of cellular response to stressGO:00801352440.166
regulation of leukocyte differentiationGO:1902105610.165
response to toxic substanceGO:0009636370.163
negative regulation of phosphorylationGO:00423261740.163
dna catabolic process endonucleolyticGO:0000737370.160
Mouse
regulation of leukocyte activationGO:00026941150.158
cellular response to xenobiotic stimulusGO:0071466290.156
response to glucocorticoidGO:0051384130.150
regulation of mononuclear cell proliferationGO:0032944650.149
response to antibioticGO:0046677150.148
cellular response to light stimulusGO:0071482340.148
neurological system processGO:00508771630.148
leukocyte differentiationGO:0002521980.144
response to corticosteroidGO:0031960150.144
negative regulation of catalytic activityGO:00430863350.143
apoptotic nuclear changesGO:0030262130.141
Mouse
cellular protein catabolic processGO:00442572610.139
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.139
regulation of neuron deathGO:1901214560.137
apoptotic mitochondrial changesGO:0008637570.135
release of cytochrome c from mitochondriaGO:0001836350.133
negative regulation of immune system processGO:00026831360.132
Fly
negative regulation of protein modification processGO:00314002000.131
neuron differentiationGO:00301821380.131
Fly
head developmentGO:00603221080.129
Mouse
cellular response to steroid hormone stimulusGO:0071383370.128
negative regulation of intracellular signal transductionGO:19025321830.128
regulation of transferase activityGO:00513383550.128
response to alcoholGO:0097305640.126
sensory perception of soundGO:0007605370.124
epithelium developmentGO:00604292270.124
Mouse
regulation of execution phase of apoptosisGO:1900117110.123
Mouse
central nervous system developmentGO:00074171230.123
Mouse Fly
cellular component disassembly involved in execution phase of apoptosisGO:0006921130.122
Mouse
myeloid leukocyte differentiationGO:0002573600.122
neuron deathGO:0070997650.117
Mouse
determination of adult lifespanGO:000834020.117
keratinocyte differentiationGO:0030216360.115
mononuclear cell proliferationGO:0032943710.115
macrophage differentiationGO:0030225110.115
cell cycle g1 s phase transitionGO:0044843800.114
response to nicotineGO:0035094120.113
response to oxygen levelsGO:00704821000.113
regulation of kinase activityGO:00435493140.113
b cell activationGO:0042113330.112
regulation of myeloid leukocyte differentiationGO:0002761390.109
negative regulation of protein serine threonine kinase activityGO:0071901570.109
sensory perception of mechanical stimulusGO:0050954370.108
signal transduction by p53 class mediatorGO:0072331720.107
t cell activationGO:0042110990.105
cardiovascular system developmentGO:00723582620.105
positive regulation of neuron deathGO:1901216140.101
regulation of dna metabolic processGO:00510521530.100
Mouse
regulation of neuron apoptotic processGO:0043523350.100
cell activationGO:00017752130.099
positive regulation of endopeptidase activityGO:0010950840.099
regulation of lymphocyte proliferationGO:0050670640.098
brain developmentGO:0007420970.095
Mouse
regulation of g1 s transition of mitotic cell cycleGO:2000045400.089
negative regulation of protein processingGO:00109551420.085
negative regulation of t cell proliferationGO:004213080.084
positive regulation of leukocyte differentiationGO:1902107370.084
regulation of cell activationGO:00508651250.084
negative regulation of peptidase activityGO:0010466910.083
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.081
regulation of t cell activationGO:0050863770.081
homeostasis of number of cellsGO:0048872400.078
response to ketoneGO:1901654190.077
response to drugGO:0042493810.076
signal transduction involved in mitotic dna damage checkpointGO:1902402130.076
negative regulation of endopeptidase activityGO:0010951840.074
cellular response to acid chemicalGO:0071229440.073
leukocyte apoptotic processGO:0071887310.073
regulation of t cell proliferationGO:0042129420.071
behaviorGO:00076101120.071
neurogenesisGO:00220081690.071
Fly
negative regulation of protein metabolic processGO:00512483910.071
kidney developmentGO:0001822530.070
cellular amine metabolic processGO:0044106410.070
b cell proliferationGO:0042100220.069
positive regulation of wnt signaling pathwayGO:0030177540.068
regulation of protein processingGO:00706131500.066
response to hypoxiaGO:0001666960.066
epidermis developmentGO:0008544590.063
forebrain developmentGO:0030900260.063
Mouse
regulation of canonical wnt signaling pathwayGO:0060828880.063
negative regulation of kinase activityGO:00336731060.062
leukocyte proliferationGO:0070661740.060
single organism cellular localizationGO:19025803320.058
cellular response to radiationGO:0071478650.058
multicellular organismal agingGO:001025930.058
skin developmentGO:0043588760.058
negative regulation of leukocyte activationGO:0002695260.057
negative regulation of proteolysisGO:00458611320.055
oogenesisGO:004847720.054
female gamete generationGO:000729220.053
cellular amino acid metabolic processGO:00065201160.053
Fly
defense responseGO:00069523150.052
Fly
regulation of cellular amine metabolic processGO:0033238110.052
response to monosaccharideGO:0034284200.052
negative regulation of protein maturationGO:19033181420.051
post embryonic developmentGO:000979120.050
Fly
protein modification by small protein conjugationGO:00324463420.048
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.047
morphogenesis of embryonic epitheliumGO:001633140.046
Mouse
organophosphate catabolic processGO:00464344300.046
purine ribonucleotide catabolic processGO:00091544040.046
positive regulation of cellular component organizationGO:00511303760.046
negative regulation of phosphate metabolic processGO:00459362670.045
neuromuscular junction developmentGO:000752830.045
wnt signaling pathwayGO:00160551560.044
t cell proliferationGO:0042098450.044
protein ubiquitinationGO:00165673140.044
t cell homeostasisGO:004302930.043
lymphocyte apoptotic processGO:0070227200.043
positive regulation of phosphorylationGO:00423273940.043
positive regulation of canonical wnt signaling pathwayGO:0090263330.042
positive regulation of cellular amine metabolic processGO:003324070.042
cell projection organizationGO:00300302520.041
Fly
regulation of activated t cell proliferationGO:0046006120.041
reactive oxygen species metabolic processGO:0072593750.040
apoptotic dna fragmentationGO:000630960.039
Mouse
epithelial cell differentiationGO:00308551410.039
regulation of response to external stimulusGO:00321012220.038
regulation of wnt signaling pathwayGO:00301111230.037
modification dependent protein catabolic processGO:00199412090.037
cellular ketone metabolic processGO:0042180800.036
small gtpase mediated signal transductionGO:0007264780.036
cytoplasmic transportGO:00164823790.036
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.035
response to retinoic acidGO:0032526330.035
vesicle mediated transportGO:00161923710.035
chemical homeostasisGO:00488783060.034
Fly
nucleoside catabolic processGO:00091644080.034
regulation of leukocyte apoptotic processGO:2000106250.034
negative regulation of cell activationGO:0050866330.034
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.033
neuron apoptotic processGO:0051402390.033
Mouse
regulation of lymphocyte apoptotic processGO:0070228150.033
cellular macromolecular complex assemblyGO:00346223240.033
membrane organizationGO:00610242920.032
ribonucleoside catabolic processGO:00424544060.032
nucleoside triphosphate metabolic processGO:00091414220.032
ras protein signal transductionGO:0007265730.031
locomotory behaviorGO:000762610.031
ubiquitin dependent protein catabolic processGO:00065112060.031
intracellular protein transportGO:00068862700.031
positive regulation of apoptotic signaling pathwayGO:2001235700.030
Mouse
protein localization to organelleGO:00333652800.030
cell divisionGO:00513011680.030
regulation of apoptotic signaling pathwayGO:20012331750.030
Mouse
nucleoside phosphate catabolic processGO:19012924120.030
release of cytoplasmic sequestered nf kappabGO:000858840.029
cell projection morphogenesisGO:00488581290.029
Fly
dephosphorylationGO:00163112090.029
negative regulation of cysteine type endopeptidase activityGO:2000117480.029
cognitionGO:0050890430.029
nucleoside triphosphate catabolic processGO:00091433940.028
positive regulation of locomotionGO:00400171860.028
motor neuron axon guidanceGO:000804520.028
cell part morphogenesisGO:00329901370.028
Fly
compound eye developmentGO:004874910.028
Fly
innate immune responseGO:00450871780.028
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
glycosyl compound catabolic processGO:19016584130.027
proteasomal protein catabolic processGO:00104981760.027
purine containing compound catabolic processGO:00725234110.027
positive regulation of cell deathGO:00109422630.027
memoryGO:000761330.027
response to nitrogen compoundGO:19016981840.027
positive regulation of protein polyubiquitinationGO:190291630.026
regulation of cellular component biogenesisGO:00440872810.026
negative regulation of t cell activationGO:0050868180.026
regulation of protein serine threonine kinase activityGO:00719001790.026
rho protein signal transductionGO:0007266260.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
purine ribonucleoside metabolic processGO:00461284370.025
Fly
regulation of nucleotide metabolic processGO:00061402690.025
regulation of meiotic cell cycleGO:005144540.025
purine nucleoside catabolic processGO:00061523980.025
cytokine productionGO:00018162470.025
spermatid developmentGO:000728640.025
Fly
regulation of protein maturationGO:19033171500.025
actin filament based processGO:00300292240.025
lipid metabolic processGO:00066293810.024
neural tube formationGO:000184130.024
Mouse
regulation of multi organism processGO:00439001570.024
single organism carbohydrate metabolic processGO:00447231930.024
melanin metabolic processGO:000658210.024
Fly
regulation of protein transportGO:00512232130.024
positive regulation of catabolic processGO:00098963100.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
response to axon injuryGO:004867810.024
regulation of synaptic plasticityGO:004816730.024
oxidation reduction processGO:00551143960.024
regulation of establishment of protein localizationGO:00702012420.024
cellular chemical homeostasisGO:00550821800.024
regulation of protein ubiquitinationGO:0031396950.024
purine ribonucleoside catabolic processGO:00461303980.023
regulation of cellular amino acid metabolic processGO:000652160.023
oocyte developmentGO:004859910.023
positive regulation of protein monoubiquitinationGO:190252710.023
defense response to other organismGO:00985421290.023
negative regulation of lymphocyte proliferationGO:0050672150.023
negative regulation of cellular component organizationGO:00511292350.023
ribonucleotide catabolic processGO:00092614050.023
cell adhesionGO:00071553250.023
secretion by cellGO:00329402260.023
neuron developmentGO:00486661130.023
Fly
regulation of neural precursor cell proliferationGO:200017740.023
negative regulation of developmental processGO:00510932470.022
chromatin organizationGO:00063253510.022
cellular lipid metabolic processGO:00442553030.022
positive regulation of response to external stimulusGO:0032103880.022
heart developmentGO:0007507950.022
response to hexoseGO:0009746200.022
cation transportGO:00068123310.022
organonitrogen compound biosynthetic processGO:19015662000.022
regulation of protein localizationGO:00328802960.022
cellular response to ketoneGO:190165590.021
organ morphogenesisGO:00098871470.021
Fly
purine nucleoside triphosphate catabolic processGO:00091463920.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
Mouse Fly
regulation of cell migrationGO:00303342890.021
cell morphogenesisGO:00009022960.021
Fly
negative regulation of hydrolase activityGO:00513461820.021
organelle assemblyGO:00709251760.021
regulation of cell motilityGO:20001452990.021
detection of stimulusGO:0051606850.021
purine nucleotide catabolic processGO:00061954050.021
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.021
erk1 and erk2 cascadeGO:00703711040.021
cell cell signalingGO:00072671550.021
negative regulation of multicellular organismal processGO:00512413170.021
regulation of purine nucleotide metabolic processGO:19005422640.021
ribonucleoside triphosphate catabolic processGO:00092033910.020
actin cytoskeleton organizationGO:00300362070.020
negative regulation of cell proliferationGO:00082852280.020
cell morphogenesis involved in differentiationGO:00009041440.020
Fly
peripheral nervous system developmentGO:000742220.020
positive regulation of transportGO:00510503360.020
negative regulation of protein kinase activityGO:0006469980.020
tube morphogenesisGO:0035239950.020
Mouse
positive regulation of protein kinase activityGO:00458601900.020
response to virusGO:00096151260.020
single organism membrane organizationGO:00448022680.020
negative regulation of apoptotic signaling pathwayGO:2001234970.020
positive regulation of cytokine productionGO:00018191670.020
positive regulation of protein k48 linked ubiquitinationGO:190252410.019
epithelial cell proliferationGO:00506731280.019
negative regulation of lymphocyte activationGO:0051250240.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
positive regulation of cellular component movementGO:00512721810.019
regulation of protein kinase activityGO:00458592890.019
regulation of locomotionGO:00400123290.019
generation of neuronsGO:00486991520.019
Fly
regulation of map kinase activityGO:00434051080.019
negative regulation of b cell proliferationGO:003088950.019
positive regulation of cellular catabolic processGO:00313312840.019
nucleotide catabolic processGO:00091664080.019
regulation of intracellular transportGO:00323861950.019
gtp metabolic processGO:00460392390.019
blood vessel morphogenesisGO:00485141620.019
transmembrane transportGO:00550853990.019
circadian behaviorGO:004851220.018
regulation of erk1 and erk2 cascadeGO:0070372990.018
maintenance of locationGO:00512351120.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
regulation of homeostatic processGO:00328441210.018
positive regulation of kinase activityGO:00336742040.018
chemotaxisGO:00069351570.018
protein localization to nucleusGO:00345041360.018
rna processingGO:00063962550.018
positive regulation of gliogenesisGO:001401540.018
regulation of cell morphogenesisGO:00226041530.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
regulation of purine nucleotide catabolic processGO:00331212050.017
rhythmic behaviorGO:000762220.017
gtp catabolic processGO:00061842370.017
positive regulation of cell migrationGO:00303351720.017
blood vessel developmentGO:00015681720.017
viral processGO:00160321460.017
oocyte differentiationGO:000999420.017
stem cell divisionGO:001714520.017
cellular protein complex assemblyGO:00436231880.017
monocarboxylic acid metabolic processGO:00327871850.017
positive regulation of transferase activityGO:00513472270.017
metal ion transportGO:00300012720.017
positive regulation of protein transportGO:00512221350.017
mapk cascadeGO:00001652880.017
luteolysisGO:000155430.017
protein importGO:00170381300.017
ossificationGO:00015031210.017
adult locomotory behaviorGO:000834410.017
protein autoprocessingGO:001654040.016
nucleoside monophosphate metabolic processGO:00091231910.016
defense response to virusGO:0051607710.016
reactive oxygen species biosynthetic processGO:190340940.016
protein targetingGO:00066051870.016
necrotic cell deathGO:0070265210.016
signal transduction by phosphorylationGO:00230142970.016
cardiac muscle cell contractionGO:008600340.016
guanosine containing compound catabolic processGO:19010692390.016
spermatid differentiationGO:004851540.016
Fly
single organism nuclear importGO:19025931040.016
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.016
establishment of protein localization to organelleGO:00725941720.016
embryo developmentGO:00097901230.016
Mouse
dna repairGO:00062811980.016
regulation of cell developmentGO:00602841610.016
Fly
ion homeostasisGO:00508012300.016
mitochondrion organizationGO:00070051560.016
regulation of cellular component movementGO:00512703340.015
cellular component morphogenesisGO:00329893140.015
Fly
nuclear transportGO:00511691790.015
regulation of cytokine productionGO:00018172320.015
cell developmentGO:00484683280.015
Fly
histone modificationGO:00165702510.015
cellular response to retinoic acidGO:0071300190.015
syncytium formation by plasma membrane fusionGO:000076820.015
cellular homeostasisGO:00197251960.015
Fly
nuclear importGO:00511701060.015
regulation of nucleotide catabolic processGO:00308112050.015
negative regulation of cellular amine metabolic processGO:003323930.015
lens development in camera type eyeGO:000208820.015

APAF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.036
cancerDOID:1621670.036
organ system cancerDOID:00506861640.025
disease of metabolismDOID:00146672950.025
inherited metabolic disorderDOID:6552420.021
musculoskeletal system diseaseDOID:172230.019
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.018
eye and adnexa diseaseDOID:14921500.017
eye diseaseDOID:56141490.017
immune system diseaseDOID:29141550.017
central nervous system diseaseDOID:3311860.015