Homo sapiens

283 known processes

TRAF6

TNF receptor-associated factor 6

(Aliases: MGC:3310,RNF85)

TRAF6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of i kappab kinase nf kappab signalingGO:00431221621.000
i kappab kinase nf kappab signalingGO:00072491661.000
protein ubiquitinationGO:00165673141.000
protein modification by small protein conjugationGO:00324463421.000
activation of nf kappab inducing kinase activityGO:000725091.000
positive regulation of i kappab kinase nf kappab signalingGO:00431231321.000
protein polyubiquitinationGO:00002091101.000
regulation of sequence specific dna binding transcription factor activityGO:00510902111.000
immune response activating signal transductionGO:0002757901.000
activation of innate immune responseGO:0002218551.000
response to bacteriumGO:00096171441.000
response to cytokineGO:00340972321.000
activation of protein kinase activityGO:0032147900.999
apoptotic signaling pathwayGO:00971902680.999
Human
positive regulation of phosphorylationGO:00423273940.999
positive regulation of protein kinase activityGO:00458601900.999
activation of jnkk activityGO:000725610.999
positive regulation of nik nf kappab signalingGO:1901224100.999
toll like receptor 2 signaling pathwayGO:003413440.999
positive regulation of protein phosphorylationGO:00019343130.998
immune response regulating signaling pathwayGO:0002764970.998
cytokine productionGO:00018162470.998
regulation of nik nf kappab signalingGO:1901222110.998
protein autoubiquitinationGO:0051865370.998
response to biotic stimulusGO:00096072760.997
activation of immune responseGO:00022531140.997
proteolysis involved in cellular protein catabolic processGO:00516032440.997
regulation of protein serine threonine kinase activityGO:00719001790.997
cytokine mediated signaling pathwayGO:00192211090.996
Human Mouse Rat
negative regulation of nf kappab transcription factor activityGO:0032088510.996
Human
pattern recognition receptor signaling pathwayGO:0002221480.996
positive regulation of mapk cascadeGO:00434101900.996
regulation of transferase activityGO:00513383550.996
cellular response to biotic stimulusGO:0071216710.995
response to molecule of bacterial originGO:0002237820.995
regulation of protein kinase activityGO:00458592890.995
response to other organismGO:00517072610.995
regulation of kinase activityGO:00435493140.994
interleukin 6 productionGO:0032635370.993
Mouse
innate immune response activating signal transductionGO:0002758480.993
regulation of immune responseGO:00507762010.993
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.992
Human
regulation of cytokine productionGO:00018172320.991
regulation of defense responseGO:00313471540.991
signal transduction by phosphorylationGO:00230142970.990
innate immune responseGO:00450871780.990
Zebrafish
cellular response to lipopolysaccharideGO:0071222570.989
positive regulation of defense responseGO:0031349870.989
response to external biotic stimulusGO:00432072610.989
nik nf kappab signalingGO:0038061120.988
regulation of cytokine mediated signaling pathwayGO:0001959410.987
regulation of t cell cytokine productionGO:0002724100.987
cellular response to cytokine stimulusGO:00713451810.986
Human Mouse Rat
positive regulation of immune system processGO:00026842830.985
positive regulation of innate immune responseGO:0045089790.985
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.984
regulation of jun kinase activityGO:0043506270.984
regulation of immune effector processGO:0002697910.984
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.981
defense responseGO:00069523150.980
Zebrafish
regulation of stress activated mapk cascadeGO:0032872840.980
ubiquitin dependent protein catabolic processGO:00065112060.977
protein catabolic processGO:00301633250.976
interleukin 2 productionGO:0032623200.974
lipopolysaccharide mediated signaling pathwayGO:0031663260.968
Mouse
positive regulation of immune responseGO:00507781590.968
regulation of protein ubiquitinationGO:0031396950.966
regulation of cytokine production involved in immune responseGO:0002718220.966
positive regulation of t cell cytokine productionGO:000272640.966
positive regulation of production of molecular mediator of immune responseGO:0002702110.966
regulation of adaptive immune responseGO:0002819330.964
regulation of apoptotic signaling pathwayGO:20012331750.964
Human
modification dependent macromolecule catabolic processGO:00436322120.963
cellular response to molecule of bacterial originGO:0071219620.961
negative regulation of apoptotic processGO:00430663160.959
protein k48 linked ubiquitinationGO:0070936380.955
positive regulation of protein serine threonine kinase activityGO:00719021190.953
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.950
Human
mapk cascadeGO:00001652880.949
neural tube formationGO:000184130.948
Mouse
positive regulation of transferase activityGO:00513472270.947
cellular protein catabolic processGO:00442572610.944
cytokine production involved in immune responseGO:0002367270.943
modification dependent protein catabolic processGO:00199412090.942
protein oligomerizationGO:00512591730.936
Human
cellular response to lipidGO:00713961270.931
regulation of tumor necrosis factor productionGO:0032680430.922
negative regulation of multicellular organismal processGO:00512413170.918
regulation of jnk cascadeGO:0046328730.915
regulation of cellular response to stressGO:00801352440.905
cellular macromolecule catabolic processGO:00442653800.890
positive regulation of kinase activityGO:00336742040.883
response to lipopolysaccharideGO:0032496700.874
negative regulation of protein catabolic processGO:0042177590.869
regulation of mapk cascadeGO:00434082620.864
negative regulation of cytokine productionGO:0001818820.861
t cell cytokine productionGO:0002369120.858
cellular response to oxygen containing compoundGO:19017012760.855
positive regulation of apoptotic signaling pathwayGO:2001235700.845
Human
positive regulation of nf kappab transcription factor activityGO:0051092810.842
immune responseGO:00069553070.841
regulation of t cell mediated immunityGO:0002709180.834
negative regulation of cytokine mediated signaling pathwayGO:0001960220.833
regulation of production of molecular mediator of immune responseGO:0002700250.830
response to lipidGO:00339932060.824
regulation of protein modification by small protein conjugation or removalGO:19033201070.820
negative regulation of tumor necrosis factor productionGO:0032720200.816
protein k63 linked ubiquitinationGO:0070534310.800
regulation of innate immune responseGO:0045088970.799
response to peptidoglycanGO:003249430.786
regulation of stress activated protein kinase signaling cascadeGO:0070302850.783
positive regulation of toll like receptor 4 signaling pathwayGO:003414560.782
response to interleukin 1GO:0070555470.782
regulation of interleukin 2 productionGO:0032663190.772
response to oxygen containing compoundGO:19017003690.766
production of molecular mediator of immune responseGO:0002440370.765
lymphocyte mediated immunityGO:0002449480.760
positive regulation of adaptive immune responseGO:0002821210.748
regulation of map kinase activityGO:00434051080.743
immune effector processGO:00022521590.743
adaptive immune responseGO:0002250490.736
positive regulation of jun kinase activityGO:0043507230.733
positive regulation of map kinase activityGO:0043406800.731
positive regulation of cell differentiationGO:00455972110.731
extrinsic apoptotic signaling pathwayGO:00971911190.726
Human
muscle cell proliferationGO:0033002350.719
Rat
er associated ubiquitin dependent protein catabolic processGO:0030433310.717
toll like receptor signaling pathwayGO:0002224250.702
leukocyte proliferationGO:0070661740.688
Mouse
regulation of protein catabolic processGO:00421761550.685
regulation of reactive oxygen species metabolic processGO:2000377410.668
tumor necrosis factor superfamily cytokine productionGO:0071706450.660
negative regulation of protein modification processGO:00314002000.636
negative regulation of programmed cell deathGO:00430693210.636
negative regulation of tumor necrosis factor mediated signaling pathwayGO:001080470.633
interleukin 1 mediated signaling pathwayGO:0070498120.616
Mouse Rat
negative regulation of tumor necrosis factor superfamily cytokine productionGO:1903556200.609
negative regulation of protein metabolic processGO:00512483910.607
negative regulation of catabolic processGO:00098951040.594
negative regulation of phosphorylationGO:00423261740.575
negative regulation of cell deathGO:00605483450.565
t cell receptor signaling pathwayGO:0050852210.564
positive regulation of toll like receptor signaling pathwayGO:0034123100.554
negative regulation of apoptotic signaling pathwayGO:2001234970.546
regulation of interleukin 1 mediated signaling pathwayGO:200065930.532
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.531
regulation of reactive oxygen species biosynthetic processGO:190342630.524
positive regulation of protein ubiquitinationGO:0031398530.523
nervous system developmentGO:00073992930.520
Mouse
cellular response to interleukin 1GO:0071347350.517
Mouse Rat
regulation of tumor necrosis factor mediated signaling pathwayGO:0010803120.502
interleukin 17 productionGO:0032620120.467
negative regulation of response to cytokine stimulusGO:0060761250.464
cellular response to external stimulusGO:00714961110.462
myeloid cell differentiationGO:00300991170.450
negative regulation of sterol transportGO:003237280.449
regulation of interleukin 12 productionGO:0032655150.446
Mouse
regulation of response to cytokine stimulusGO:0060759460.445
negative regulation of protein serine threonine kinase activityGO:0071901570.439
protein deubiquitinationGO:0016579790.438
cellular component disassemblyGO:0022411920.435
dna repairGO:00062811980.433
positive regulation of interleukin 2 productionGO:0032743110.431
mitotic cell cycle phase transitionGO:00447721620.424
negative regulation of interleukin 6 productionGO:0032715130.409
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.404
intracellular receptor signaling pathwayGO:00305221040.401
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.396
cellular response to bacterial lipoproteinGO:007122030.394
negative regulation of mapk cascadeGO:0043409560.393
defense response to bacteriumGO:0042742630.391
negative regulation of intracellular signal transductionGO:19025321830.387
nucleotide binding oligomerization domain containing signaling pathwayGO:007042340.385
negative regulation of immune system processGO:00026831360.383
regulation of cell activationGO:00508651250.382
Mouse
immune system developmentGO:00025201950.368
leukocyte mediated immunityGO:0002443590.368
regulation of leukocyte mediated immunityGO:0002703380.362
positive regulation of cytokine productionGO:00018191670.352
smooth muscle cell proliferationGO:0048659280.351
Rat
negative regulation of protein kinase activityGO:0006469980.347
positive regulation of cytokine biosynthetic processGO:0042108250.346
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.345
antigen receptor mediated signaling pathwayGO:0050851380.336
negative regulation of protein ubiquitinationGO:0031397350.334
regulation of protein localizationGO:00328802960.332
Mouse
negative regulation of kinase activityGO:00336731060.323
regulation of protein transportGO:00512232130.320
Mouse
proteasomal protein catabolic processGO:00104981760.319
regulation of response to external stimulusGO:00321012220.307
Mouse
negative regulation of protein phosphorylationGO:00019331400.302
positive regulation of t cell mediated immunityGO:0002711120.301
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.296
regulation of peptidase activityGO:00525471800.283
protein k63 linked deubiquitinationGO:0070536210.278
protein autophosphorylationGO:00467771230.276
leukocyte differentiationGO:0002521980.274
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.267
embryonic epithelial tube formationGO:000183840.266
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.265
regulation of endothelial cell apoptotic processGO:2000351240.264
regulation of cell differentiationGO:00455953930.263
negative regulation of transferase activityGO:00513481240.251
negative regulation of multi organism processGO:0043901920.250
jnk cascadeGO:0007254800.245
activation of mapkk activityGO:0000186180.239
toll like receptor 4 signaling pathwayGO:0034142120.238
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.238
neuroblast proliferationGO:000740540.237
negative regulation of catalytic activityGO:00430863350.236
negative regulation of map kinase activityGO:0043407270.233
negative regulation of cholesterol effluxGO:009037020.233
positive regulation of mononuclear cell proliferationGO:0032946470.232
Mouse
protein monoubiquitinationGO:0006513390.229
response to fungusGO:000962040.226
positive regulation of protein bindingGO:0032092240.224
Human
regulation of proteolysisGO:00301622930.222
Human
cellular response to tumor necrosis factorGO:0071356630.203
Human
positive regulation of cell activationGO:0050867810.202
Mouse
endodermal cell fate specificationGO:000171440.200
endothelial cell apoptotic processGO:0072577260.197
cellular macromolecular complex assemblyGO:00346223240.195
negative regulation of cholesterol transportGO:003237580.192
regulation of mononuclear cell proliferationGO:0032944650.190
Mouse
i kappab phosphorylationGO:000725270.187
positive regulation of leukocyte activationGO:0002696800.182
Mouse
cellular response to dna damage stimulusGO:00069743790.180
negative regulation of protein maturationGO:19033181420.177
positive regulation of lymphocyte activationGO:0051251730.175
Mouse
negative regulation of phosphate metabolic processGO:00459362670.174
regulation of cd40 signaling pathwayGO:200034830.174
circulatory system developmentGO:00723592620.171
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.165
lymphocyte homeostasisGO:000226040.159
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043140.156
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.155
negative regulation of proteolysisGO:00458611320.146
cardiovascular system developmentGO:00723582620.144
negative regulation of phosphorus metabolic processGO:00105632670.142
reactive oxygen species metabolic processGO:0072593750.142
positive regulation of stress activated mapk cascadeGO:0032874600.140
response to abiotic stimulusGO:00096283360.140
agingGO:0007568660.132
toll like receptor 3 signaling pathwayGO:003413840.129
stress activated protein kinase signaling cascadeGO:0031098940.129
positive regulation of toll like receptor 3 signaling pathwayGO:003414110.128
positive regulation of interleukin 23 productionGO:003274740.127
regulation of autophagyGO:0010506520.126
positive regulation of dna metabolic processGO:0051054730.121
response to nitrogen compoundGO:19016981840.121
multicellular organismal agingGO:001025930.121
regulation of secretionGO:00510461940.120
Mouse
response to organonitrogen compoundGO:00102431560.118
regulation of proteasomal protein catabolic processGO:0061136870.117
negative regulation of endopeptidase activityGO:0010951840.117
regulation of interferon beta productionGO:0032648220.116
protein k11 linked deubiquitinationGO:003587190.116
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.116
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.115
regulation of smooth muscle cell proliferationGO:0048660280.115
Rat
regulation of cytokine biosynthetic processGO:0042035350.113
Mouse
chemokine productionGO:0032602320.113
neurogenesisGO:00220081690.112
tumor necrosis factor mediated signaling pathwayGO:0033209270.110
Human
b cell activationGO:0042113330.108
positive regulation of cellular amino acid metabolic processGO:004576430.106
positive regulation of protein catabolic processGO:0045732750.105
response to nitric oxideGO:007173140.105
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.105
modulation of growth of symbiont involved in interaction with hostGO:004414420.104
positive regulation of smooth muscle cell proliferationGO:0048661140.104
Rat
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.102
positive regulation of apoptotic processGO:00430652460.102
Human
hematopoietic or lymphoid organ developmentGO:00485341860.101
negative regulation of protein complex disassemblyGO:0043242200.098
cellular response to abiotic stimulusGO:00712141170.098
immune response activating cell surface receptor signaling pathwayGO:0002429450.097
mitotic cell cycleGO:00002783260.097
regulation of ion transmembrane transportGO:00347651320.096
protein modification by small protein removalGO:0070646920.095
positive regulation of chemokine productionGO:0032722220.095
regulation of t cell receptor signaling pathwayGO:005085670.094
sterol transportGO:0015918390.093
positive regulation of proteolysisGO:00458621420.093
programmed necrotic cell deathGO:0097300180.090
negative regulation of interleukin 1 mediated signaling pathwayGO:200066020.090
positive regulation of catabolic processGO:00098963100.089
morphogenesis of embryonic epitheliumGO:001633140.089
Mouse
regulation of cellular protein catabolic processGO:1903362960.089
growthGO:00400072020.088
type i interferon productionGO:0032606270.085
regulation of protein complex assemblyGO:00432541470.085
nuclear divisionGO:00002801280.085
lymphocyte activationGO:00466491330.085
Mouse
response to mechanical stimulusGO:0009612510.085
autophagyGO:0006914880.083
regulation of interleukin 6 productionGO:0032675370.083
Mouse
regulation of cell cycleGO:00517263930.083
negative regulation of neurological system processGO:003164520.082
regulation of protein bindingGO:0043393660.082
Human
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753120.081
post embryonic developmentGO:000979120.081
organelle fissionGO:00482851490.080
regulation of response to dna damage stimulusGO:2001020940.079
positive regulation of cell cycleGO:00457871400.079
regulation of growthGO:00400081650.079
neural nucleus developmentGO:0048857470.079
growth involved in symbiotic interactionGO:004411020.077
nitric oxide biosynthetic processGO:0006809200.076
negative regulation of leukocyte activationGO:0002695260.075
heart developmentGO:0007507950.075
regulation of toll like receptor signaling pathwayGO:0034121170.075
spinal cord developmentGO:002151040.075
forebrain generation of neuronsGO:002187230.075
cellular amino acid metabolic processGO:00065201160.074
muscle cell fate commitmentGO:004269340.074
regulation of potassium ion transmembrane transportGO:1901379200.072
cellular lipid metabolic processGO:00442553030.072
negative regulation of toll like receptor 3 signaling pathwayGO:003414020.071
inflammatory responseGO:0006954790.071
positive regulation of jnk cascadeGO:0046330520.071
protein k48 linked deubiquitinationGO:0071108190.069
regulation of cysteine type endopeptidase activityGO:20001161270.069
negative regulation of type i interferon productionGO:003248050.069
positive regulation of osteoclast differentiationGO:004567290.069
response to organic cyclic compoundGO:00140702040.069
response to radiationGO:00093141510.068
positive regulation of toll like receptor 2 signaling pathwayGO:003413720.068
negative regulation of reactive oxygen species metabolic processGO:2000378110.068
negative regulation of proteasomal protein catabolic processGO:1901799320.067
regulation of bindingGO:00510981110.067
embryonic morphogenesisGO:0048598850.067
Mouse
regulation of leukocyte proliferationGO:0070663670.066
Mouse
lipid transportGO:0006869900.065
regulation of endopeptidase activityGO:00525481700.065
protein complex disassemblyGO:0043241520.065
stem cell divisionGO:001714520.064
immune response regulating cell surface receptor signaling pathwayGO:0002768510.064
cell divisionGO:00513011680.062
macromolecular complex disassemblyGO:0032984600.061
mrna metabolic processGO:00160711750.061
asymmetric neuroblast divisionGO:005505910.061
regulation of protein polyubiquitinationGO:190291480.060
regulation of toll like receptor 2 signaling pathwayGO:003413520.060
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.060
negative regulation of necroptotic processGO:006054620.059
regulation of wnt signaling pathwayGO:00301111230.059
positive regulation of transcription regulatory region dna bindingGO:200067980.058
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.058
Human
regulation of transmembrane transportGO:00347621390.057
tissue morphogenesisGO:0048729960.057
Mouse
regulation of response to biotic stimulusGO:0002831550.057
Mouse
chemokine metabolic processGO:005075540.056
b cell homeostasisGO:000178210.055
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.055
defense response to virusGO:0051607710.055
regulation of protein complex disassemblyGO:0043244280.054
male meiosisGO:000714010.054
positive regulation of peptidase activityGO:0010952880.053
rna catabolic processGO:0006401710.052
compound eye developmentGO:004874910.052
reactive nitrogen species metabolic processGO:200105730.052
cellular response to heatGO:0034605140.052
endodermal cell fate commitmentGO:000171140.051
regulation of establishment of protein localizationGO:00702012420.051
Mouse
myeloid leukocyte differentiationGO:0002573600.050
negative regulation of toll signaling pathwayGO:004575110.050
response to light stimulusGO:0009416870.050
regulation of lymphocyte apoptotic processGO:0070228150.050
interleukin 8 productionGO:0032637510.050
histone ubiquitinationGO:0016574310.049
cell type specific apoptotic processGO:00972851250.049
protein localization to nucleusGO:00345041360.048
regulation of leukocyte activationGO:00026941150.047
Mouse
regulation of antigen receptor mediated signaling pathwayGO:0050854100.047
response to extracellular stimulusGO:0009991850.047
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.046
mature b cell differentiationGO:000233510.046
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.046
regulation of protein processingGO:00706131500.045
response to starvationGO:0042594590.045
fatty acid metabolic processGO:00066311150.045
regulation of protein stabilityGO:0031647870.043
positive regulation of t cell activationGO:0050870540.043
Mouse
negative regulation of chemokine productionGO:003268290.042
spermatid differentiationGO:004851540.042
cellular lipid catabolic processGO:0044242650.042
response to endoplasmic reticulum stressGO:0034976490.042
toll signaling pathwayGO:000806320.042
negative regulation of lipopolysaccharide mediated signaling pathwayGO:003166570.042
regulation of cell divisionGO:00513021160.042
wnt signaling pathwayGO:00160551560.040
tube morphogenesisGO:0035239950.040
Mouse
positive regulation of cellular catabolic processGO:00313312840.040
endodermal cell differentiationGO:0035987310.040
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.040
regulation of cellular amino acid metabolic processGO:000652160.039
negative regulation of jun kinase activityGO:004350840.039
determination of adult lifespanGO:000834020.039
regulation of lipid transportGO:0032368440.039
cellular response to starvationGO:0009267580.038
positive regulation of b cell proliferationGO:0030890120.038
regulation of protein localization to plasma membraneGO:1903076400.038
growth of symbiont involved in interaction with hostGO:004411620.038
head developmentGO:00603221080.038
positive regulation of cellular component organizationGO:00511303760.037
negative regulation of interleukin 12 productionGO:003269560.037
regulation of protein linear polyubiquitinationGO:190252820.036
regulation of osteoclast differentiationGO:0045670180.036
response to virusGO:00096151260.036
Zebrafish
apoptotic mitochondrial changesGO:0008637570.036
positive regulation of protein linear polyubiquitinationGO:190253020.035
cellular response to uvGO:0034644320.035
regulation of ion transportGO:00432691890.035
symbiosis encompassing mutualism through parasitismGO:00444031560.035
regulation of protein localization to nucleusGO:1900180850.035
chemical homeostasisGO:00488783060.035
regulation of gene expression epigeneticGO:0040029730.035
negative regulation of macrophage cytokine productionGO:001093630.035
cellular response to misfolded proteinGO:007121820.035
lymphocyte apoptotic processGO:0070227200.034
defense response to gram negative bacteriumGO:0050829140.034
embryo developmentGO:00097901230.034
Mouse
regulation of lymphocyte activationGO:00512491030.034
Mouse
response to tumor necrosis factorGO:0034612760.034
Human
epithelium developmentGO:00604292270.034
Mouse
jak stat cascadeGO:0007259460.033
ion transmembrane transportGO:00342203380.033
cell activationGO:00017752130.033
Mouse
lipid metabolic processGO:00066293810.032
brain developmentGO:0007420970.032
embryonic heart tube developmentGO:003505090.032
microtubule cytoskeleton organizationGO:00002261760.032
negative regulation of protein transportGO:0051224750.031
positive regulation of dendrite morphogenesisGO:005077530.031
negative regulation of protein processingGO:00109551420.030
formation of primary germ layerGO:0001704420.029
negative regulation of defense responseGO:0031348470.029
negative regulation of peptidase activityGO:0010466910.029
protein processingGO:00164852260.029
positive regulation of cell developmentGO:0010720920.029
positive regulation of chemokine biosynthetic processGO:004508030.029
negative regulation of stress activated protein kinase signaling cascadeGO:0070303190.028
regulation of type i interferon productionGO:0032479260.028
regulation of t cell activationGO:0050863770.028
Mouse
positive regulation of lymphocyte mediated immunityGO:0002708230.028
regulation of cell growthGO:00015581350.027
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.027
rna interferenceGO:001624640.027
immunoglobulin secretionGO:004830510.026
Mouse
negative regulation of cysteine type endopeptidase activityGO:2000117480.026
chromosome segregationGO:00070591140.026
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.026
eye developmentGO:0001654420.026
rna processingGO:00063962550.026
negative regulation of striated muscle cell apoptotic processGO:001066420.026
regulation of neurotransmitter secretionGO:004692830.026
mitotic cell cycle processGO:19030472860.025
negative regulation of cell cycleGO:00457861930.025
negative regulation of smooth muscle cell proliferationGO:0048662140.025
cell growthGO:00160491600.025
er associated misfolded protein catabolic processGO:007171210.025
protein acetylationGO:00064731160.025
positive regulation of developmental processGO:00510943140.025
meiosis iGO:000712740.025
covalent chromatin modificationGO:00165692540.025
defense response to other organismGO:00985421290.025
regulation of nervous system developmentGO:0051960880.025
cellular response to oxidative stressGO:0034599850.024
regulation of toll like receptor 3 signaling pathwayGO:003413920.024
response to growth factorGO:00708482050.024
regulation of interleukin 17 productionGO:0032660120.024
ripoptosome assemblyGO:009734310.024
cell agingGO:0007569520.024
cdc42 protein signal transductionGO:003248840.024
response to hypoxiaGO:0001666960.024
t cell activationGO:0042110990.024
Mouse
neurological system processGO:00508771630.023
negative regulation of transportGO:00510511760.023
cholesterol transportGO:0030301390.023
positive regulation of growthGO:0045927580.023
response to uvGO:0009411730.023
positive regulation of interferon beta biosynthetic processGO:004535940.023

TRAF6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:114680.125
cardiovascular system diseaseDOID:12871060.125
skin diseaseDOID:37330.108
integumentary system diseaseDOID:16430.108
musculoskeletal system diseaseDOID:172230.093
cancerDOID:1621670.078
organ system cancerDOID:00506861640.078
disease of cellular proliferationDOID:145661740.078
muscular diseaseDOID:00800001140.037
myopathyDOID:4231040.037
muscle tissue diseaseDOID:661130.037
intrinsic cardiomyopathyDOID:0060036500.026
cardiomyopathyDOID:0050700500.026