Homo sapiens

244 known processes

SMAD7

SMAD family member 7

(Aliases: CRCS3,MADH8,MADH7,FLJ16482)

SMAD7 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015481.000
regulation of activin receptor signaling pathwayGO:0032925141.000
positive regulation of stem cell differentiationGO:2000738291.000
Human
cardiac cell fate determinationGO:006091331.000
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092901.000
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100411.000
Human
transforming growth factor beta receptor signaling pathwayGO:0007179761.000
cellular response to transforming growth factor beta stimulusGO:0071560941.000
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781251.000
positive regulation of osteoblast differentiationGO:0045669231.000
response to transforming growth factor betaGO:0071559941.000
activin receptor signaling pathwayGO:0032924241.000
regulation of stem cell differentiationGO:2000736561.000
Human
regulation of pathway restricted smad protein phosphorylationGO:0060393341.000
negative regulation of gliogenesisGO:001401430.999
protein ubiquitinationGO:00165673140.999
evasion or tolerance of host defensesGO:004441520.999
Human
endodermal cell fate commitmentGO:000171140.999
endodermal cell fate specificationGO:000171440.999
protein modification by small protein conjugationGO:00324463420.999
positive regulation of bmp signaling pathwayGO:003051390.999
Human
stem cell differentiationGO:0048863930.999
Human Fly
response to sterolGO:0036314140.999
Human
stem cell developmentGO:0048864690.998
Human Fly
cellular response to growth factor stimulusGO:00713631970.998
positive regulation of cytoplasmic transportGO:1903651820.998
Human
regulation of protein modification by small protein conjugation or removalGO:19033201070.998
somatic stem cell maintenanceGO:003501940.998
regulation of smad protein import into nucleusGO:0060390100.997
regulation of osteoblast differentiationGO:0045667380.996
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.996
intracellular protein transportGO:00068862700.996
Human
enzyme linked receptor protein signaling pathwayGO:00071673030.996
negative regulation of pathway restricted smad protein phosphorylationGO:0060394110.995
formation of primary germ layerGO:0001704420.995
cardiac muscle tissue developmentGO:0048738390.995
Mouse
canonical wnt signaling pathwayGO:00600701160.995
Human
regulation of protein ubiquitinationGO:0031396950.994
response to growth factorGO:00708482050.994
cell cycle arrestGO:0007050710.994
Human
positive regulation of developmental processGO:00510943140.993
Human
positive regulation of pathway restricted smad protein phosphorylationGO:0010862220.993
positive regulation of cell differentiationGO:00455972110.993
Human
smad protein complex assemblyGO:0007183120.992
Human
wnt signaling pathwayGO:00160551560.991
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.991
positive regulation of epithelial to mesenchymal transitionGO:0010718220.991
Human
common partner smad protein phosphorylationGO:000718230.991
Human
regulation of canonical wnt signaling pathwayGO:0060828880.990
Human
positive regulation of ossificationGO:0045778320.990
mesenchymal cell developmentGO:0014031500.988
Human
cellular response to endogenous stimulusGO:00714953360.987
negative regulation of bmp signaling pathwayGO:0030514170.987
epithelial to mesenchymal transitionGO:0001837480.987
Human
regulation of cell differentiationGO:00455953930.986
Human Fly
regulation of cellular amine metabolic processGO:0033238110.986
pathway restricted smad protein phosphorylationGO:0060389380.986
regulation of cellular response to growth factor stimulusGO:0090287760.985
positive regulation of cysteine type endopeptidase activityGO:2001056790.984
Human
cell fate commitment involved in formation of primary germ layerGO:006079560.984
response to cholesterolGO:0070723110.983
Human
skeletal system developmentGO:0001501790.982
protein import into nucleusGO:00066061040.982
Human
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512280.982
peptidyl threonine phosphorylationGO:0018107410.981
evasion or tolerance of host defenses by virusGO:001904920.980
Human
regulation of cellular amino acid metabolic processGO:000652160.979
mitotic cell cycle phase transitionGO:00447721620.979
positive regulation of smad protein import into nucleusGO:006039180.979
positive regulation of cell developmentGO:0010720920.978
Human
protein targeting to nucleusGO:00447441040.977
Human
negative regulation of cell proliferationGO:00082852280.976
Human
positive regulation of programmed cell deathGO:00430682490.975
Human
modulation by virus of host morphology or physiologyGO:0019048100.975
Human
lateral mesoderm developmentGO:004836810.974
Human
regulation of protein targetingGO:1903533910.973
Human
regulation of nucleocytoplasmic transportGO:0046822980.973
Human
positive regulation of nucleocytoplasmic transportGO:0046824540.972
Human
epithelium developmentGO:00604292270.972
Mouse Fly
nodal signaling pathwayGO:003809250.971
Human
mesonephric epithelium developmentGO:0072163140.969
Mouse
regulation of intracellular protein transportGO:00331571230.969
Human
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.969
Human
positive regulation of mesenchymal stem cell differentiationGO:200074140.969
positive regulation of protein localization to nucleusGO:1900182480.968
Human
regulation of cartilage developmentGO:0061035120.967
protein importGO:00170381300.967
Human
negative regulation of glial cell proliferationGO:006025320.966
positive regulation of mapk cascadeGO:00434101900.964
stem cell maintenanceGO:0019827190.964
Fly
osteoblast differentiationGO:0001649920.963
bmp signaling pathwayGO:0030509490.963
cardiocyte differentiationGO:0035051230.962
regulation of protein import into nucleusGO:0042306780.962
Human
regulation of epithelial to mesenchymal transitionGO:0010717370.961
Human
positive regulation of male gonad developmentGO:200002030.960
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.960
Human
modification of morphology or physiology of other organismGO:0035821430.960
Human
atrial septum primum morphogenesisGO:000328910.957
regulation of mesoderm developmentGO:200038040.957
Human
negative regulation of cell differentiationGO:00455961710.957
Fly
mapk cascadeGO:00001652880.956
regulation of wnt signaling pathwayGO:00301111230.955
Human
negative regulation of peptidyl threonine phosphorylationGO:001080160.955
transforming growth factor beta productionGO:0071604140.954
Human
regulation of protein localization to nucleusGO:1900180850.952
Human
cell fate determinationGO:000170930.952
endoderm formationGO:0001706330.952
negative regulation of wnt signaling pathwayGO:0030178690.950
mesenchyme developmentGO:0060485590.947
Human
regulation of mapk cascadeGO:00434082620.946
positive regulation of cell deathGO:00109422630.945
Human
positive regulation of proteasomal protein catabolic processGO:1901800350.943
mitotic cell cycleGO:00002783260.941
Human
determination of left right asymmetry in lateral mesodermGO:000314010.940
Human
endodermal cell differentiationGO:0035987310.940
protein localization to organelleGO:00333652800.940
Human
organ morphogenesisGO:00098871470.940
Mouse Fly
positive regulation of chondrocyte differentiationGO:003233240.939
regulation of cellular ketone metabolic processGO:0010565500.939
negative regulation of cellular response to growth factor stimulusGO:0090288410.939
chondrocyte differentiationGO:0002062170.939
regulation of protein transportGO:00512232130.939
Human
modification dependent macromolecule catabolic processGO:00436322120.938
positive regulation of protein ubiquitinationGO:0031398530.937
peptidyl serine phosphorylationGO:00181051010.937
cellular amine metabolic processGO:0044106410.935
negative regulation of trophoblast cell migrationGO:190116430.935
avoidance of defenses of other organism involved in symbiotic interactionGO:005183220.934
Human
amine metabolic processGO:0009308440.931
nucleocytoplasmic transportGO:00069131760.928
Human
regulation of cytoplasmic transportGO:19036491490.927
Human
protein localization to nucleusGO:00345041360.926
Human
negative regulation of developmental processGO:00510932470.926
Fly
cellular amino acid metabolic processGO:00065201160.924
negative regulation of chondrocyte proliferationGO:190273110.923
digestive tract developmentGO:0048565750.922
Fly
pituitary gland developmentGO:002198320.921
catenin import into nucleusGO:0035411180.921
Human
embryonic morphogenesisGO:0048598850.920
Fly
nuclear transportGO:00511691790.919
Human
digestive tract morphogenesisGO:0048546560.919
Fly
single organism nuclear importGO:19025931040.917
Human
negative regulation of transcription by competitive promoter bindingGO:001094480.916
tube morphogenesisGO:0035239950.913
Fly
regulation of protein localizationGO:00328802960.912
Human
regulation of ligase activityGO:0051340290.911
kidney epithelium developmentGO:0072073250.911
Mouse
neuron fate commitmentGO:004866320.911
mitral valve morphogenesisGO:000318320.910
regulation of protein catabolic processGO:00421761550.909
negative regulation of protein metabolic processGO:00512483910.907
renal system developmentGO:0072001630.907
Mouse Fly
positive regulation of canonical wnt signaling pathwayGO:0090263330.906
Human
mesenchymal cell differentiationGO:0048762520.906
Human
regulation of proteolysisGO:00301622930.906
kidney developmentGO:0001822530.904
Mouse
response to oxygen containing compoundGO:19017003690.904
Human
cartilage developmentGO:0051216310.904
determination of dorsal ventral asymmetryGO:004826240.903
positive regulation of phosphorylationGO:00423273940.899
bmp signaling pathway involved in heart developmentGO:006131230.898
regulation of chondrocyte differentiationGO:003233090.894
response to organic cyclic compoundGO:00140702040.893
Human
regulation of bmp signaling pathwayGO:0030510270.893
positive regulation of protein transportGO:00512221350.890
Human
positive regulation of intracellular transportGO:00323881040.887
Human
cytoplasmic transportGO:00164823790.887
Human
tube developmentGO:00352951250.887
Mouse Fly
negative regulation of protein modification processGO:00314002000.886
cell cycle phase transitionGO:00447701730.885
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.884
connective tissue developmentGO:0061448390.884
regulation of establishment of protein localizationGO:00702012420.882
Human
digestive system developmentGO:0055123750.881
Fly
positive regulation of peptidase activityGO:0010952880.881
Human
establishment of protein localization to organelleGO:00725941720.880
Human
regulation of cell developmentGO:00602841610.876
Human
regulation of transferase activityGO:00513383550.876
endocardial cushion cell differentiationGO:006144310.872
hard palate developmentGO:006002210.867
regulation of peptidase activityGO:00525471800.858
Human
mitral valve developmentGO:000317430.856
regulation of epithelial cell migrationGO:0010632930.853
regulation of erythrocyte differentiationGO:0045646170.853
negative regulation of phosphate metabolic processGO:00459362670.849
negative regulation of protein ubiquitinationGO:0031397350.849
negative regulation of chorionic trophoblast cell proliferationGO:190138320.845
cell developmentGO:00484683280.845
Human Fly
regulation of muscle organ developmentGO:0048634270.842
Fly
regionalizationGO:0003002290.842
Human Fly
regulation of cell growthGO:00015581350.841
Human
peptidyl serine modificationGO:00182091060.836
negative regulation of programmed cell deathGO:00430693210.835
Human
heart morphogenesisGO:0003007480.834
Mouse
response to woundingGO:00096111680.833
signal transduction by phosphorylationGO:00230142970.833
negative regulation of growthGO:0045926970.832
Human Fly
positive regulation of intracellular protein transportGO:0090316760.824
Human
regulation of cellular component movementGO:00512703340.824
regulation of endopeptidase activityGO:00525481700.818
Human
circulatory system developmentGO:00723592620.815
Mouse
embryonic heart tube morphogenesisGO:000314380.809
regulation of cell migrationGO:00303342890.808
positive regulation of cellular catabolic processGO:00313312840.804
regulation of growthGO:00400081650.804
Human Fly
positive regulation of protein import into nucleusGO:0042307460.799
Human
chondrocyte developmentGO:000206310.799
positive regulation of apoptotic processGO:00430652460.790
Human
positive regulation of biomineral tissue developmentGO:0070169200.788
apoptotic signaling pathwayGO:00971902680.787
Human
urogenital system developmentGO:0001655650.779
Mouse Fly
response to host defensesGO:005220020.778
Human
negative regulation of cell growthGO:0030308830.776
Human
cell substrate adhesionGO:00315891320.775
Human
regulation of kinase activityGO:00435493140.774
protein catabolic processGO:00301633250.773
atrial septum morphogenesisGO:006041350.772
regulation of sequence specific dna binding transcription factor activityGO:00510902110.772
segmentationGO:003528240.771
vasculature developmentGO:00019441810.769
Mouse
positive regulation of catabolic processGO:00098963100.768
positive regulation of epithelial cell proliferationGO:0050679650.763
somitogenesisGO:000175620.763
response to biotic stimulusGO:00096072760.758
Human
regulation of cell adhesionGO:00301551660.757
negative regulation of ubiquitin protein transferase activityGO:005144480.756
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.752
extrinsic apoptotic signaling pathwayGO:00971911190.751
Human
blood vessel morphogenesisGO:00485141620.748
Mouse
regulation of cysteine type endopeptidase activityGO:20001161270.744
Human
regulation of proteasomal protein catabolic processGO:0061136870.743
positive regulation of determination of dorsal identityGO:200001710.739
regulation of cell cycleGO:00517263930.737
Human
positive regulation of erythrocyte differentiationGO:0045648110.735
muscle cell fate commitmentGO:004269340.731
regulation of catenin import into nucleusGO:0035412180.729
Human
anatomical structure formation involved in morphogenesisGO:00486462840.727
positive regulation of protein phosphorylationGO:00019343130.726
negative regulation of cellular protein metabolic processGO:00322693530.723
gastrulationGO:0007369510.721
regulation of male gonad developmentGO:200001840.717
modification dependent protein catabolic processGO:00199412090.717
endothelium developmentGO:0003158330.716
cardiovascular system developmentGO:00723582620.715
Mouse
regulation of determination of dorsal identityGO:200001520.715
negative regulation of cell cycleGO:00457861930.713
Human
positive regulation of cartilage developmentGO:006103670.704
adherens junction organizationGO:0034332360.704
zygotic specification of dorsal ventral axisGO:000735220.703
Human
determination of bilateral symmetryGO:0009855150.702
Human
interspecies interaction between organismsGO:00444191560.691
Human
adherens junction assemblyGO:0034333340.691
nodal signaling pathway involved in determination of left right asymmetryGO:003810710.688
Human
cellular response to bmp stimulusGO:007177380.685
cell junction organizationGO:0034330790.685
chondrocyte differentiation involved in endochondral bone morphogenesisGO:000341310.683
nuclear importGO:00511701060.681
Human
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.679
Human
regulation of neuron differentiationGO:0045664700.678
positive regulation of cell motilityGO:20001471770.672
posttranscriptional regulation of gene expressionGO:00106082130.668
cardiac muscle cell fate commitmentGO:006092340.664
cellular response to dna damage stimulusGO:00069743790.663
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.662
cytokine productionGO:00018162470.656
Human
cardiac atrium morphogenesisGO:000320970.656
epithelial cell fate commitmentGO:007214830.651
regulation of intracellular transportGO:00323861950.649
Human
cell junction assemblyGO:0034329670.648
mitotic cell cycle processGO:19030472860.647
positive regulation of cellular component movementGO:00512721810.646
regulation of cell cell adhesionGO:0022407570.643
myeloid cell homeostasisGO:0002262340.641
epithelial cell proliferationGO:00506731280.639
positive regulation of cellular component organizationGO:00511303760.638
Human
immune system developmentGO:00025201950.634
endochondral bone morphogenesisGO:006035030.634
cell cycle g1 s phase transitionGO:0044843800.632
determination of dorsal identityGO:004826340.631
regulation of cell cycle arrestGO:0071156360.629
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.621
Human
blood vessel endothelial cell migrationGO:0043534420.618
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016410.613
Human
negative regulation of canonical wnt signaling pathwayGO:0090090550.609
regulation of myeloid cell differentiationGO:0045637810.609
positive regulation of apoptotic signaling pathwayGO:2001235700.608
single organism cellular localizationGO:19025803320.604
Human
fat cell differentiationGO:0045444320.602
Human
protein targetingGO:00066051870.602
Human
cellular ketone metabolic processGO:0042180800.602
cellular macromolecule catabolic processGO:00442653800.601
sex determinationGO:000753030.599
biomineral tissue developmentGO:0031214390.599
angiogenesisGO:00015251470.598
retinal ganglion cell axon guidanceGO:003129020.596
Fly
regulation of protein stabilityGO:0031647870.595
tissue morphogenesisGO:0048729960.593
Mouse Fly
positive regulation of reproductive processGO:200024390.591
negative regulation of peptidyl serine phosphorylationGO:003313780.586
regulation of mrna export from nucleusGO:001079330.584
cell growthGO:00160491600.583
Human Fly
negative regulation of apoptotic processGO:00430663160.581
Human
positive regulation of kinase activityGO:00336742040.580
lymphocyte activationGO:00466491330.579
positive regulation of map kinase activityGO:0043406800.575
cellular protein catabolic processGO:00442572610.575
heart developmentGO:0007507950.573
Mouse
g1 s transition of mitotic cell cycleGO:0000082780.573
negative regulation of phosphorylationGO:00423261740.573
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152220.570
regulation of adherens junction organizationGO:1903391210.570
mesonephric tubule developmentGO:0072164140.570
Mouse
negative regulation of cellular amine metabolic processGO:003323930.570
negative regulation of mitotic cell cycle phase transitionGO:1901991850.567
endocardial cell differentiationGO:006095620.563
ubiquitin dependent protein catabolic processGO:00065112060.559
cardiac chamber morphogenesisGO:0003206260.557
Mouse
ossificationGO:00015031210.557
epithelial cell differentiationGO:00308551410.554
regulation of glial cell proliferationGO:006025140.554
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.550
regulation of cell matrix adhesionGO:0001952420.548
endoderm developmentGO:0007492330.545
myeloid cell differentiationGO:00300991170.544
regulation of i kappab kinase nf kappab signalingGO:00431221620.544
regulation of locomotionGO:00400123290.543
protein acetylationGO:00064731160.542
bone mineralizationGO:0030282340.541
positive regulation of bone mineralizationGO:0030501190.539
negative regulation of mitotic cell cycleGO:00459301020.538
Human
regulation of chorionic trophoblast cell proliferationGO:190138220.536
regulation of cell motilityGO:20001452990.536
morphogenesis of an epitheliumGO:0002009600.534
Fly
regulation of mitotic cell cycleGO:00073461890.533
Human
protein stabilizationGO:0050821640.533
positive regulation of epithelial cell migrationGO:0010634550.531
proteolysis involved in cellular protein catabolic processGO:00516032440.531
cell activationGO:00017752130.530
head developmentGO:00603221080.530
response to defenses of other organism involved in symbiotic interactionGO:005217320.526
Human
positive regulation of transportGO:00510503360.521
Human
endodermal mesodermal cell signalingGO:000313330.521
regulation of heart induction by regulation of canonical wnt signaling pathwayGO:009008110.517
wound healingGO:00420601150.515
homeostasis of number of cellsGO:0048872400.515
male sex differentiationGO:0046661250.512
positive regulation of activin receptor signaling pathwayGO:003292760.508
Human
hemopoiesisGO:00300971800.505
positive regulation of cell proliferationGO:00082843010.504
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.503
regulation of mitotic cell cycle phase transitionGO:19019901180.502
cell fate commitmentGO:0045165270.502
muscle tissue developmentGO:0060537620.502
Mouse
positive regulation of trophoblast cell migrationGO:190116520.502
negative regulation of multicellular organismal processGO:00512413170.492
Fly
regulation of ossificationGO:0030278580.489
embryonic skeletal joint developmentGO:007249820.484
development involved in symbiotic interactionGO:004411110.482
negative regulation of immune system processGO:00026831360.481
peptidyl lysine modificationGO:00182051440.480
mesonephros developmentGO:0001823170.477
Mouse
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.477
activation of protein kinase activityGO:0032147900.476
regulation of cell cycle processGO:00105642660.474
positive regulation of hydrolase activityGO:00513453310.474
Human
atrial septum developmentGO:000328380.474
negative regulation of cell deathGO:00605483450.470
Human
response to hostGO:007513620.470
Human
positive regulation of protein kinase activityGO:00458601900.469
regulation of protein serine threonine kinase activityGO:00719001790.466
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.459
chromatin organizationGO:00063253510.459
neural crest cell developmentGO:001403230.458
positive regulation of cell migrationGO:00303351720.457
biological adhesionGO:00226103310.457
n terminal peptidyl lysine acetylationGO:001807640.454
positive regulation of mesenchymal cell proliferationGO:000205320.453
positive regulation of transferase activityGO:00513472270.444
regulation of transcription factor import into nucleusGO:0042990390.443
Human
chordate embryonic developmentGO:0043009340.438
positive regulation of stress activated mapk cascadeGO:0032874600.433
cardiac cell fate commitmentGO:006091170.424
regulation of leukocyte activationGO:00026941150.423
regulation of reactive oxygen species metabolic processGO:2000377410.422
negative regulation of phosphorus metabolic processGO:00105632670.420
specification of symmetryGO:0009799160.419
Human
blastocyst formationGO:000182530.417
chorionic trophoblast cell proliferationGO:009736020.415
regulation of bone mineralizationGO:0030500290.413
positive regulation of catenin import into nucleusGO:003541390.413
Human
negative regulation of ligase activityGO:005135280.411
positive regulation of cellular protein catabolic processGO:1903364370.410
regulation of nervous system developmentGO:0051960880.409
Fly
regulation of cell morphogenesis involved in differentiationGO:0010769830.409
Human
embryo developmentGO:00097901230.404
Human Fly
positive regulation of cell adhesionGO:0045785840.400
mesodermal cell fate commitmentGO:000171020.400
cellular macromolecular complex assemblyGO:00346223240.393
Human
positive regulation of protein serine threonine kinase activityGO:00719021190.393
symbiosis encompassing mutualism through parasitismGO:00444031560.393
Human
erythrocyte homeostasisGO:0034101310.393
regulation of cellular component biogenesisGO:00440872810.392
Human Fly
regulation of cell morphogenesisGO:00226041530.391
Human
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190017510.391
Human
mesoderm morphogenesisGO:0048332110.390
negative regulation of sodium ion transmembrane transporter activityGO:200065020.389
negative regulation of protein phosphorylationGO:00019331400.387
positive regulation of cellular amino acid metabolic processGO:004576430.387
blood vessel developmentGO:00015681720.381
Mouse
regulation of methylation dependent chromatin silencingGO:009030830.381
chromatin assembly or disassemblyGO:0006333780.379
multi organism cellular processGO:00447641560.378
Human
stem cell proliferationGO:0072089250.377
response to lipidGO:00339932060.371
Human
negative regulation of cell adhesionGO:0007162640.369
regulation of protein kinase activityGO:00458592890.368
regulation of stem cell proliferationGO:0072091150.366
cellular response to external stimulusGO:00714961110.364
endothelial cell migrationGO:0043542860.364
response to abiotic stimulusGO:00096283360.362
Human
response to bmpGO:007177280.359
growthGO:00400072020.358
Human Fly
regulation of lymphocyte activationGO:00512491030.356
system processGO:00030083490.355
Mouse
regulation of epithelial cell proliferationGO:00506781130.354
regulation of stress activated mapk cascadeGO:0032872840.352
prostate gland developmentGO:003085030.349
ubiquitin dependent smad protein catabolic processGO:003057940.348
endocardial cell fate commitmentGO:006095710.347
cartilage development involved in endochondral bone morphogenesisGO:006035120.346
dna damage checkpointGO:0000077680.344
regulation of smad protein complex assemblyGO:001099040.340
Human
leukocyte activationGO:00453211640.339
negative regulation of smad protein complex assemblyGO:001099140.338
Human
positive regulation of cellular amine metabolic processGO:003324070.336
neuron differentiationGO:00301821380.336
Fly
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.335
Human
protein processingGO:00164852260.335
Human
dna damage response detection of dna damageGO:004276930.333
hematopoietic or lymphoid organ developmentGO:00485341860.331
viral processGO:00160321460.330
Human
regulation of endothelial cell migrationGO:0010594670.329
muscle structure developmentGO:0061061980.329
Mouse Fly
positive regulation of proteolysisGO:00458621420.328
cardiac endothelial cell differentiationGO:000334820.328
muscle system processGO:0003012810.326
Mouse
regulation of nodal signaling pathway involved in determination of left right asymmetryGO:190014510.324
Human
positive regulation of cell cycleGO:00457871400.321
positive regulation of endothelial cell migrationGO:0010595390.319
regulation of apoptotic signaling pathwayGO:20012331750.314
positive regulation of protein catabolic processGO:0045732750.313
cardiac chamber developmentGO:0003205300.311
Mouse
negative regulation of epithelial cell proliferationGO:0050680480.310
mesoderm developmentGO:0007498140.308
Human
regulation of transforming growth factor beta2 productionGO:003290960.305
Human
forebrain generation of neuronsGO:002187230.305
stem cell divisionGO:001714520.305
negative regulation of nervous system developmentGO:0051961280.303
Fly
reactive oxygen species metabolic processGO:0072593750.303
embryonic skeletal system developmentGO:0048706130.302
response to other organismGO:00517072610.301
Human
cardiac septum morphogenesisGO:006041190.300
Mouse
response to oxygen levelsGO:00704821000.299
Human
negative regulation of muscle organ developmentGO:0048635120.299
Fly
atrioventricular valve developmentGO:000317130.298
negative regulation of cellular amino acid metabolic processGO:004576320.297
pattern specification processGO:0007389430.297
Human Fly
positive regulation of nervous system developmentGO:0051962540.297
regulation of homeostatic processGO:00328441210.295
regulation of cell activationGO:00508651250.295
septum primum developmentGO:000328410.293
embryonic organ morphogenesisGO:0048562240.292
negative regulation of protein transportGO:0051224750.292
chromatin modificationGO:00165682980.290
heart formationGO:006091420.287
nuclear exportGO:0051168690.286
neurogenesisGO:00220081690.284
Fly
single organismal cell cell adhesionGO:00163371480.282
forebrain regionalizationGO:002187130.280
positive regulation of cell cycle arrestGO:0071158230.280
smad protein import into nucleusGO:0007184130.279
response to external biotic stimulusGO:00432072610.278
Human
protein polyubiquitinationGO:00002091100.276
regulation of lung blood pressureGO:001491610.275
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076710.274
endocardial cushion cell fate commitmentGO:006144510.274
avoidance of host defensesGO:004441320.269
Human
negative regulation of systemic arterial blood pressureGO:000308510.269
positive regulation of odontogenesisGO:004248230.267
protein export from nucleusGO:0006611290.265
response to alcoholGO:0097305640.263
Human
ameboidal type cell migrationGO:00016671350.263
negative regulation of apoptotic signaling pathwayGO:2001234970.263
regenerationGO:003109940.261
trna transportGO:005103110.261

SMAD7 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
heart diseaseDOID:114680.763
Human
cardiovascular system diseaseDOID:12871060.763
Human