Homo sapiens

0 known processes

KLB

klotho beta

(Aliases: BKL,MGC142213)

KLB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of bile acid biosynthetic processGO:007085830.567
small molecule biosynthetic processGO:00442831570.310
cellular ketone metabolic processGO:0042180800.296
lipid metabolic processGO:00066293810.282
regulation of cellular ketone metabolic processGO:0010565500.224
cellular response to endogenous stimulusGO:00714953360.207
monocarboxylic acid metabolic processGO:00327871850.200
cellular response to fibroblast growth factor stimulusGO:0044344390.186
monocarboxylic acid biosynthetic processGO:0072330670.183
lipid biosynthetic processGO:00086101770.180
carboxylic acid biosynthetic processGO:0046394970.166
bile acid metabolic processGO:0008206140.162
steroid metabolic processGO:0008202940.149
negative regulation of lipid metabolic processGO:0045833380.143
organic hydroxy compound metabolic processGO:19016151470.140
positive regulation of mapk cascadeGO:00434101900.116
positive regulation of phosphorylationGO:00423273940.111
cellular response to growth factor stimulusGO:00713631970.108
positive regulation of erk1 and erk2 cascadeGO:0070374750.098
regulation of erk1 and erk2 cascadeGO:0070372990.092
enzyme linked receptor protein signaling pathwayGO:00071673030.087
regulation of mapk cascadeGO:00434082620.086
organic hydroxy compound biosynthetic processGO:1901617710.085
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.080
signal transduction by phosphorylationGO:00230142970.079
regulation of cellular response to stressGO:00801352440.078
regulation of glucose importGO:0046324210.077
positive regulation of transportGO:00510503360.074
regulation of steroid metabolic processGO:0019218320.073
positive regulation of cell proliferationGO:00082843010.073
stress activated protein kinase signaling cascadeGO:0031098940.070
post embryonic developmentGO:000979120.070
jnk cascadeGO:0007254800.068
regulation of lipid metabolic processGO:0019216960.066
erk1 and erk2 cascadeGO:00703711040.063
regulation of jnk cascadeGO:0046328730.060
fibroblast growth factor receptor signaling pathwayGO:0008543260.060
regulation of lipid biosynthetic processGO:0046890470.058
positive regulation of stress activated mapk cascadeGO:0032874600.056
amine metabolic processGO:0009308440.056
response to fibroblast growth factorGO:0071774390.055
cellular amine metabolic processGO:0044106410.053
regulation of cellular amine metabolic processGO:0033238110.052
positive regulation of jnk cascadeGO:0046330520.051
regulation of steroid biosynthetic processGO:0050810230.050
positive regulation of cellular amino acid metabolic processGO:004576430.045
regulation of stress activated protein kinase signaling cascadeGO:0070302850.044
regulation of stress activated mapk cascadeGO:0032872840.043
negative regulation of lipid biosynthetic processGO:0051055220.039
female gamete generationGO:000729220.038
stress activated mapk cascadeGO:0051403930.037
carbohydrate transportGO:0008643370.036
multicellular organismal agingGO:001025930.036
determination of adult lifespanGO:000834020.035
ribonucleoside triphosphate metabolic processGO:00091994120.034
immune responseGO:00069553070.033
bile acid biosynthetic processGO:0006699100.033
cellular lipid metabolic processGO:00442553030.033
negative regulation of cell deathGO:00605483450.032
purine ribonucleoside metabolic processGO:00461284370.032
positive regulation of hydrolase activityGO:00513453310.032
regulation of proteolysisGO:00301622930.031
chemical homeostasisGO:00488783060.031
biological adhesionGO:00226103310.031
cell adhesionGO:00071553250.031
negative regulation of protein metabolic processGO:00512483910.031
oogenesisGO:004847720.030
locomotory behaviorGO:000762610.030
system processGO:00030083490.030
negative regulation of cellular protein metabolic processGO:00322693530.030
cellular amino acid metabolic processGO:00065201160.030
carbohydrate metabolic processGO:00059752070.029
ribonucleoside catabolic processGO:00424544060.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
regulation of transferase activityGO:00513383550.028
nucleoside triphosphate catabolic processGO:00091433940.028
positive regulation of glucose transportGO:0010828170.028
defense responseGO:00069523150.028
purine nucleoside catabolic processGO:00061523980.028
segmentationGO:003528240.028
monosaccharide transportGO:0015749320.027
negative regulation of catalytic activityGO:00430863350.027
regulation of anatomical structure morphogenesisGO:00226032860.027
response to oxygen containing compoundGO:19017003690.027
regulation of glucose transportGO:0010827230.027
positive regulation of protein phosphorylationGO:00019343130.027
regenerationGO:003109940.027
nucleoside triphosphate metabolic processGO:00091414220.027
positive regulation of immune system processGO:00026842830.026
single organism cellular localizationGO:19025803320.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
regulation of kinase activityGO:00435493140.026
cation transportGO:00068123310.025
protein catabolic processGO:00301633250.025
purine ribonucleotide catabolic processGO:00091544040.025
small gtpase mediated signal transductionGO:0007264780.025
hexose transportGO:0008645300.025
negative regulation of apoptotic processGO:00430663160.025
regulation of cell differentiationGO:00455953930.024
neuromuscular junction developmentGO:000752830.024
organ formationGO:004864530.024
regulation of cell cycleGO:00517263930.024
positive regulation of catabolic processGO:00098963100.024
positive regulation of cellular component organizationGO:00511303760.024
regulation of protein kinase activityGO:00458592890.024
protein maturationGO:00516042330.024
purine nucleotide catabolic processGO:00061954050.024
negative regulation of programmed cell deathGO:00430693210.024
regulation of cell migrationGO:00303342890.023
response to abiotic stimulusGO:00096283360.023
regulation of establishment of protein localizationGO:00702012420.023
regulation of nucleotide metabolic processGO:00061402690.023
membrane organizationGO:00610242920.023
regulation of cytokine productionGO:00018172320.023
organic acid biosynthetic processGO:0016053970.023
purine ribonucleoside catabolic processGO:00461303980.023
circulatory system developmentGO:00723592620.023
regulation of locomotionGO:00400123290.023
ras protein signal transductionGO:0007265730.023
innate immune responseGO:00450871780.023
positive regulation of cellular amine metabolic processGO:003324070.023
cellular homeostasisGO:00197251960.023
purine containing compound catabolic processGO:00725234110.022
oxidation reduction processGO:00551143960.022
cellular macromolecular complex assemblyGO:00346223240.022
inner ear morphogenesisGO:004247240.022
glucose transportGO:0015758300.021
response to biotic stimulusGO:00096072760.021
positive regulation of developmental processGO:00510943140.021
Human
nerve developmentGO:002167540.021
negative regulation of phosphorus metabolic processGO:00105632670.021
mapk cascadeGO:00001652880.021
apoptotic signaling pathwayGO:00971902680.021
regulation of purine nucleotide metabolic processGO:19005422640.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
cytoplasmic transportGO:00164823790.021
secretion by cellGO:00329402260.021
regulation of protein transportGO:00512232130.021
cellular protein catabolic processGO:00442572610.021
secretionGO:00469032540.020
mitotic cell cycle processGO:19030472860.020
cellular component morphogenesisGO:00329893140.020
cellular response to dna damage stimulusGO:00069743790.020
regulation of cellular amino acid metabolic processGO:000652160.020
vesicle mediated transportGO:00161923710.020
metal ion transportGO:00300012720.020
maintenance of locationGO:00512351120.020
negative regulation of cell proliferationGO:00082852280.020
single organism membrane organizationGO:00448022680.020
anterior posterior axis specificationGO:000994820.020
actin cytoskeleton organizationGO:00300362070.020
nucleoside catabolic processGO:00091644080.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
cell morphogenesisGO:00009022960.020
response to growth factorGO:00708482050.020
nucleoside phosphate catabolic processGO:19012924120.020
anion transportGO:00068201610.020
ion homeostasisGO:00508012300.019
mitotic cell cycleGO:00002783260.019
organonitrogen compound biosynthetic processGO:19015662000.019
negative regulation of phosphate metabolic processGO:00459362670.019
specification of organ identityGO:001009230.019
response to organic cyclic compoundGO:00140702040.019
hindbrain developmentGO:003090230.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
response to other organismGO:00517072610.019
negative regulation of cellular amine metabolic processGO:003323930.019
rho protein signal transductionGO:0007266260.019
oocyte developmentGO:004859910.019
blastoderm segmentationGO:000735020.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
dephosphorylationGO:00163112090.018
glycosyl compound catabolic processGO:19016584130.018
limbic system developmentGO:002176130.018
morphogenesis of embryonic epitheliumGO:001633140.018
cellular chemical homeostasisGO:00550821800.018
organophosphate catabolic processGO:00464344300.018
positive regulation of apoptotic processGO:00430652460.018
positive regulation of cellular catabolic processGO:00313312840.018
memoryGO:000761330.018
cellular macromolecule catabolic processGO:00442653800.018
actin filament based processGO:00300292240.018
cation homeostasisGO:00550801890.018
negative regulation of protein modification processGO:00314002000.018
ion transmembrane transportGO:00342203380.018
cell fate determinationGO:000170930.018
cardiac muscle cell contractionGO:008600340.017
nucleoside monophosphate metabolic processGO:00091231910.017
transmembrane transportGO:00550853990.017
positive regulation of cell deathGO:00109422630.017
regulation of protein localizationGO:00328802960.017
regulation of endopeptidase activityGO:00525481700.017
tissue regenerationGO:004224630.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
positive regulation of nucleoside metabolic processGO:00459791860.017
protein localization to organelleGO:00333652800.017
cellular cation homeostasisGO:00300031630.017
reactive oxygen species biosynthetic processGO:190340940.017
protein ubiquitinationGO:00165673140.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
neuroblast proliferationGO:000740540.017
positive regulation of nucleotide metabolic processGO:00459812300.017
oocyte differentiationGO:000999420.017
reactive oxygen species metabolic processGO:0072593750.017
glucose importGO:0046323240.017
cell activationGO:00017752130.017
negative regulation of cellular component organizationGO:00511292350.017
spermatid differentiationGO:004851540.017
negative regulation of intracellular signal transductionGO:19025321830.017
protein modification by small protein conjugationGO:00324463420.017
regulation of nucleotide catabolic processGO:00308112050.017
growthGO:00400072020.016
peripheral nervous system developmentGO:000742220.016
single organism carbohydrate metabolic processGO:00447231930.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.016
blood vessel morphogenesisGO:00485141620.016
protein targetingGO:00066051870.016
response to hormoneGO:00097251750.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
embryonic epithelial tube formationGO:000183840.016
negative regulation of cell cycleGO:00457861930.016
regulation of growthGO:00400081650.016
cell projection organizationGO:00300302520.016
response to lipidGO:00339932060.016
positive regulation of programmed cell deathGO:00430682490.016
response to nitrogen compoundGO:19016981840.016
cellular ion homeostasisGO:00068731680.016
regulation of cell adhesionGO:00301551660.016
negative regulation of transportGO:00510511760.016
cellular protein complex assemblyGO:00436231880.016
fatty acid metabolic processGO:00066311150.016
modification dependent protein catabolic processGO:00199412090.016
response to cytokineGO:00340972320.016
organophosphate biosynthetic processGO:00904071630.016
proteasomal protein catabolic processGO:00104981760.016
regulation of cytoskeleton organizationGO:00514931770.015
microtubule based processGO:00070172100.015
endomembrane system organizationGO:00102561960.015
sensory perception of painGO:001923340.015
nucleocytoplasmic transportGO:00069131760.015
positive regulation of nucleotide catabolic processGO:00308131850.015
positive regulation of organelle organizationGO:00106381950.015
posttranscriptional regulation of gene expressionGO:00106082130.015
regulation of mitotic cell cycleGO:00073461890.015
negative regulation of phosphorylationGO:00423261740.015
intracellular protein transportGO:00068862700.015
regulation of neural precursor cell proliferationGO:200017740.015
cell proliferation in forebrainGO:002184610.015
establishment of protein localization to organelleGO:00725941720.015
regulation of defense responseGO:00313471540.015
organic anion transportGO:00157111030.015
spermatid developmentGO:000728640.015
response to fungusGO:000962040.015
ribonucleotide catabolic processGO:00092614050.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
ubiquitin dependent protein catabolic processGO:00065112060.015
gtp metabolic processGO:00460392390.015
nucleotide catabolic processGO:00091664080.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
positive regulation of protein transportGO:00512221350.015
nuclear transportGO:00511691790.015
regulation of protein catabolic processGO:00421761550.015
guanosine containing compound metabolic processGO:19010682440.015
regulation of cellular component biogenesisGO:00440872810.015
adult locomotory behaviorGO:000834410.015
negative regulation of locomotionGO:00400131180.015
cranial nerve developmentGO:002154540.015
cell cycle phase transitionGO:00447701730.015
protein processingGO:00164852260.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
regulation of nucleoside metabolic processGO:00091182090.014
forebrain generation of neuronsGO:002187230.014
reactive nitrogen species metabolic processGO:200105730.014
cell growthGO:00160491600.014
salivary gland morphogenesisGO:000743540.014
positive regulation of cell differentiationGO:00455972110.014
tripartite regional subdivisionGO:000735120.014
anterior posterior axis specification embryoGO:000859520.014
glycerolipid metabolic processGO:00464861070.014
epithelium developmentGO:00604292270.014
metal ion homeostasisGO:00550651690.014
negative regulation of hydrolase activityGO:00513461820.014
cellular response to oxygen containing compoundGO:19017012760.014
regulation of cardiac muscle tissue growthGO:005502140.014
modification dependent macromolecule catabolic processGO:00436322120.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
photoreceptor cell differentiationGO:004653020.014
nervous system developmentGO:00073992930.014
rhythmic behaviorGO:000762220.014
regulation of dna metabolic processGO:00510521530.014
vasculature developmentGO:00019441810.014
regulation of intracellular transportGO:00323861950.014
regulation of protein processingGO:00706131500.014
sequestering of metal ionGO:0051238240.014
gtp catabolic processGO:00061842370.014
negative regulation of steroid metabolic processGO:0045939150.014
hemopoiesisGO:00300971800.014
protein localization to membraneGO:00726571600.014
epithelial cell proliferationGO:00506731280.014
neurological system processGO:00508771630.014
actin filament based movementGO:0030048170.014
response to external biotic stimulusGO:00432072610.014
regulation of heart growthGO:006042040.014
response to inorganic substanceGO:00100351270.014
compound eye developmentGO:004874910.014
nitrogen compound transportGO:00717051910.014
negative regulation of cellular component movementGO:00512711060.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
negative regulation of steroid biosynthetic processGO:0010894150.014
divalent inorganic cation homeostasisGO:00725071360.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
positive regulation of cellular component biogenesisGO:00440891580.014
circadian behaviorGO:004851220.014
cellular response to lipidGO:00713961270.014
positive regulation of immune responseGO:00507781590.013
regulation of peptidase activityGO:00525471800.013
interspecies interaction between organismsGO:00444191560.013
positive regulation of cell migrationGO:00303351720.013
negative regulation of protein processingGO:00109551420.013
regulation of response to external stimulusGO:00321012220.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
positive regulation of locomotionGO:00400171860.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
angiogenesisGO:00015251470.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
regulation of protein serine threonine kinase activityGO:00719001790.013
regulation of purine nucleotide catabolic processGO:00331212050.013
inorganic cation transmembrane transportGO:00986621940.013
carbohydrate derivative biosynthetic processGO:19011372070.013
regulation of organ formationGO:000315640.013
regulation of cardiac muscle cell proliferationGO:006004340.013
rna processingGO:00063962550.013
negative regulation of growthGO:0045926970.013
chromatin modificationGO:00165682980.013
negative regulation of multicellular organismal processGO:00512413170.013
positive regulation of transferase activityGO:00513472270.013
divalent inorganic cation transportGO:00725111580.013
inorganic ion transmembrane transportGO:00986602310.013
chromatin organizationGO:00063253510.013
protein oligomerizationGO:00512591730.013
lipid transportGO:0006869900.013
protein importGO:00170381300.013
negative regulation of developmental processGO:00510932470.013
regulation of cytoplasmic transportGO:19036491490.013
peptidyl tyrosine phosphorylationGO:00181081700.013
positive regulation of synaptic transmissionGO:005080640.013
cell developmentGO:00484683280.013
endodermal cell fate specificationGO:000171440.013
negative regulation of cell migrationGO:00303361020.013
alcohol metabolic processGO:00060661140.013
guanosine containing compound catabolic processGO:19010692390.013
regulation of cell morphogenesisGO:00226041530.013
neural tube formationGO:000184130.013
dna repairGO:00062811980.013
forebrain neuron differentiationGO:002187930.013
ossificationGO:00015031210.013
Human
regulation of actin filament based processGO:00329701410.013
mitochondrion organizationGO:00070051560.013
morphogenesis of a polarized epitheliumGO:000173830.013
wnt signaling pathwayGO:00160551560.013
microtubule cytoskeleton organizationGO:00002261760.013
regulation of cell cycle processGO:00105642660.012
phospholipid metabolic processGO:0006644990.012
negative regulation of protein phosphorylationGO:00019331400.012
epithelial cell differentiationGO:00308551410.012
nucleoside monophosphate catabolic processGO:00091251590.012
developmental programmed cell deathGO:001062330.012
epithelial tube branching involved in lung morphogenesisGO:006044140.012
syncytium formation by plasma membrane fusionGO:000076820.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
positive regulation of kinase activityGO:00336742040.012
glycoprotein metabolic processGO:00091001100.012
leukocyte activationGO:00453211640.012
mesodermal cell fate specificationGO:000750120.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of intracellular protein transportGO:00331571230.012
cellular response to nitrogen compoundGO:19016991440.012
positive regulation of proteolysisGO:00458621420.012
histone modificationGO:00165702510.012
regulation of protein maturationGO:19033171500.012
protein localization to nucleusGO:00345041360.012
atp metabolic processGO:00460341760.012
ectodermal placode developmentGO:007169610.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
regulation of cell growthGO:00015581350.012
striated muscle contractionGO:0006941520.012
regulation of cellular component movementGO:00512703340.012
sensory perception of smellGO:000760820.012
somitogenesisGO:000175620.012
regulation of membrane potentialGO:0042391950.012
viral processGO:00160321460.012
rna interferenceGO:001624640.012
negative regulation of proteolysisGO:00458611320.012
protein acylationGO:00435431380.012
positive regulation of cell motilityGO:20001471770.012
multi organism cellular processGO:00447641560.012
cation transmembrane transportGO:00986552380.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
wound healingGO:00420601150.012
positive regulation of cellular component movementGO:00512721810.012
lipid catabolic processGO:0016042840.012
covalent chromatin modificationGO:00165692540.012
cell projection assemblyGO:00300311260.012
regulation of gtpase activityGO:00430871800.012
response to virusGO:00096151260.012
neurotransmitter secretionGO:000726940.012
metencephalon developmentGO:002203720.012
sequestering of calcium ionGO:0051208170.012
regulation of protein complex assemblyGO:00432541470.012
sensory perceptionGO:00076001030.012
protein homooligomerizationGO:00512601000.012
cytokine productionGO:00018162470.012
motor neuron axon guidanceGO:000804520.012
regulation of immune responseGO:00507762010.012
lipid localizationGO:00108761060.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
positive regulation of gtp catabolic processGO:00331261660.012
response to oxidative stressGO:00069791210.011
anatomical structure homeostasisGO:00602491000.011
spinal cord developmentGO:002151040.011
positive regulation of neural precursor cell proliferationGO:200017920.011
regulation of protein secretionGO:0050708860.011
establishment of protein localization to membraneGO:00901501210.011
divalent metal ion transportGO:00708381520.011
primary neural tube formationGO:001402030.011
negative regulation of organelle organizationGO:00106391260.011
activation of immune responseGO:00022531140.011
negative regulation of blood pressureGO:004577630.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
ameboidal type cell migrationGO:00016671350.011
neurogenesisGO:00220081690.011
stem cell divisionGO:001714520.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
cardiac muscle contractionGO:0060048340.011
pituitary gland developmentGO:002198320.011
tube closureGO:006060630.011
cellular response to hormone stimulusGO:00328701250.011
negative regulation of cell differentiationGO:00455961710.011
regulation of synaptic plasticityGO:004816730.011
associative learningGO:000830610.011
protein autophosphorylationGO:00467771230.011
cofactor metabolic processGO:0051186870.011
visual behaviorGO:000763220.011
calcium ion homeostasisGO:00550741220.011
regulation of secretionGO:00510461940.011
sex determinationGO:000753030.011
establishment of planar polarityGO:000173630.011
positive regulation of keratinocyte migrationGO:005154940.011
cell part morphogenesisGO:00329901370.011
organ inductionGO:000175940.011
plasma membrane organizationGO:00070091150.011
regulation of secretion by cellGO:19035301770.011
epidermis morphogenesisGO:004873030.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
response to bacteriumGO:00096171440.011
engulfment of apoptotic cellGO:004365220.011
endosomal transportGO:00161971290.011
regulation of meiotic cell cycleGO:005144540.011
regulation of epithelial cell proliferationGO:00506781130.011
regulation of sensory perceptionGO:005193130.011
positive regulation of protein kinase activityGO:00458601900.011
negative regulation of immune system processGO:00026831360.011
startle responseGO:000196430.011
endodermal cell fate commitmentGO:000171140.011
neural tube closureGO:000184330.011
thymus developmentGO:004853830.011
actin mediated cell contractionGO:0070252120.011
negative regulation of protein maturationGO:19033181420.011
meiosis iGO:000712740.011
negative regulation of synaptic transmissionGO:005080520.011
cerebral cortex cell migrationGO:002179530.011

KLB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.031
inherited metabolic disorderDOID:6552420.025
nervous system diseaseDOID:8634310.024
sensory system diseaseDOID:00501552030.024
musculoskeletal system diseaseDOID:172230.018
central nervous system diseaseDOID:3311860.018
connective tissue diseaseDOID:651090.017
disease of cellular proliferationDOID:145661740.017
bone diseaseDOID:0080001880.017
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016
retinal diseaseDOID:56791180.016
organ system cancerDOID:00506861640.015
cancerDOID:1621670.015
retinal degenerationDOID:8466890.013
neurodegenerative diseaseDOID:12891020.013
immune system diseaseDOID:29141550.012
bone development diseaseDOID:0080006550.012
muscle tissue diseaseDOID:661130.011
muscular diseaseDOID:00800001140.011