Homo sapiens

65 known processes

DDB2

damage-specific DNA binding protein 2, 48kDa

(Aliases: DDBB,FLJ34321,UV-DDB2)

DDB2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic cell cycle phase transitionGO:00447721620.486
regulation of cell cycle processGO:00105642660.442
regulation of mitotic cell cycleGO:00073461890.410
dna damage checkpointGO:0000077680.383
negative regulation of cell cycle processGO:00109481210.330
cell cycle checkpointGO:00000751170.319
regulation of mitotic cell cycle phase transitionGO:19019901180.313
cellular response to dna damage stimulusGO:00069743790.310
regulation of cell cycle phase transitionGO:19019871260.310
dna repairGO:00062811980.271
mitotic cell cycle processGO:19030472860.266
dna integrity checkpointGO:0031570710.263
mitotic dna damage checkpointGO:0044773280.262
mitotic cell cycleGO:00002783260.258
regulation of cell cycleGO:00517263930.255
mitotic cell cycle checkpointGO:0007093680.249
response to uvGO:0009411730.222
cell cycle phase transitionGO:00447701730.163
regulation of cell cycle g1 s phase transitionGO:1902806420.161
response to light stimulusGO:0009416870.151
negative regulation of cell cycleGO:00457861930.149
nucleotide excision repairGO:0006289310.146
post embryonic developmentGO:000979120.120
negative regulation of mitotic cell cycle phase transitionGO:1901991850.118
negative regulation of cell cycle phase transitionGO:1901988890.116
response to radiationGO:00093141510.113
negative regulation of mitotic cell cycleGO:00459301020.109
response to abiotic stimulusGO:00096283360.108
mitotic dna integrity checkpointGO:0044774300.108
cellular macromolecule catabolic processGO:00442653800.107
apoptotic signaling pathwayGO:00971902680.097
negative regulation of programmed cell deathGO:00430693210.094
negative regulation of cell deathGO:00605483450.092
positive regulation of cell deathGO:00109422630.081
protein modification by small protein conjugationGO:00324463420.079
regulation of dna metabolic processGO:00510521530.075
protein ubiquitinationGO:00165673140.066
histone h2a monoubiquitinationGO:0035518110.065
protein maturationGO:00516042330.063
histone h2a ubiquitinationGO:0033522170.063
regulation of cell differentiationGO:00455953930.060
purine ribonucleotide catabolic processGO:00091544040.057
cellular protein catabolic processGO:00442572610.057
cellular response to abiotic stimulusGO:00712141170.055
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.052
regulation of proteolysisGO:00301622930.050
negative regulation of apoptotic processGO:00430663160.050
modification dependent protein catabolic processGO:00199412090.050
regulation of cellular amine metabolic processGO:0033238110.050
intra s dna damage checkpointGO:003157340.048
regulation of g1 s transition of mitotic cell cycleGO:2000045400.047
ubiquitin dependent protein catabolic processGO:00065112060.046
amine metabolic processGO:0009308440.046
positive regulation of cell proliferationGO:00082843010.045
cellular amine metabolic processGO:0044106410.045
multicellular organismal agingGO:001025930.042
proteolysis involved in cellular protein catabolic processGO:00516032440.042
glycosyl compound catabolic processGO:19016584130.042
cellular amino acid metabolic processGO:00065201160.042
proteasomal protein catabolic processGO:00104981760.041
modification dependent macromolecule catabolic processGO:00436322120.039
regulation of cellular amino acid metabolic processGO:000652160.039
protein processingGO:00164852260.038
positive regulation of proteolysisGO:00458621420.037
carbohydrate metabolic processGO:00059752070.036
response to uv bGO:0010224100.036
epithelium developmentGO:00604292270.035
protein catabolic processGO:00301633250.035
determination of adult lifespanGO:000834020.035
positive regulation of apoptotic processGO:00430652460.035
vesicle mediated transportGO:00161923710.034
regulation of locomotionGO:00400123290.034
ribonucleoside triphosphate catabolic processGO:00092033910.033
small gtpase mediated signal transductionGO:0007264780.033
somatic stem cell maintenanceGO:003501940.033
regulation of transferase activityGO:00513383550.032
female gamete generationGO:000729220.032
regulation of cellular ketone metabolic processGO:0010565500.032
positive regulation of cell cycle processGO:00900681060.032
positive regulation of hydrolase activityGO:00513453310.032
mapk cascadeGO:00001652880.032
positive regulation of programmed cell deathGO:00430682490.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
g1 s transition of mitotic cell cycleGO:0000082780.031
lipid metabolic processGO:00066293810.029
atp metabolic processGO:00460341760.029
immune system developmentGO:00025201950.029
leukocyte differentiationGO:0002521980.028
negative regulation of catalytic activityGO:00430863350.028
positive regulation of transportGO:00510503360.028
cytoplasmic transportGO:00164823790.028
segmentationGO:003528240.028
signal transduction by phosphorylationGO:00230142970.028
covalent chromatin modificationGO:00165692540.028
organophosphate catabolic processGO:00464344300.027
ras protein signal transductionGO:0007265730.027
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.027
nucleoside catabolic processGO:00091644080.027
negative regulation of protein metabolic processGO:00512483910.027
nucleotide catabolic processGO:00091664080.027
developmental programmed cell deathGO:001062330.026
cellular response to uvGO:0034644320.026
cellular ketone metabolic processGO:0042180800.026
negative regulation of cellular protein metabolic processGO:00322693530.026
regulation of kinase activityGO:00435493140.026
positive regulation of cellular catabolic processGO:00313312840.026
cell competition in a multicellular organismGO:003521210.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.026
protein monoubiquitinationGO:0006513390.025
nucleoside triphosphate catabolic processGO:00091433940.025
regulation of establishment of protein localizationGO:00702012420.025
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.025
purine nucleoside catabolic processGO:00061523980.025
positive regulation of catabolic processGO:00098963100.025
regulation of protein localizationGO:00328802960.025
nucleic acid phosphodiester bond hydrolysisGO:00903051020.025
microtubule based processGO:00070172100.025
negative regulation of phosphorus metabolic processGO:00105632670.025
regulation of multi organism processGO:00439001570.024
cellular response to radiationGO:0071478650.024
hemopoiesisGO:00300971800.024
cellular response to endogenous stimulusGO:00714953360.024
negative regulation of cell proliferationGO:00082852280.024
purine ribonucleoside metabolic processGO:00461284370.023
negative regulation of phosphate metabolic processGO:00459362670.023
negative regulation of intracellular signal transductionGO:19025321830.023
regulation of growthGO:00400081650.023
positive regulation of cellular amine metabolic processGO:003324070.023
intrinsic apoptotic signaling pathwayGO:00971931270.023
lipid biosynthetic processGO:00086101770.022
regulation of cellular response to stressGO:00801352440.022
negative regulation of multicellular organismal processGO:00512413170.022
nucleoside phosphate catabolic processGO:19012924120.022
chromatin modificationGO:00165682980.022
regulation of protein catabolic processGO:00421761550.022
signal transduction by p53 class mediatorGO:0072331720.022
single organism carbohydrate metabolic processGO:00447231930.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
oogenesisGO:004847720.022
regulation of endopeptidase activityGO:00525481700.022
immune responseGO:00069553070.022
ribonucleoside triphosphate metabolic processGO:00091994120.022
extrinsic apoptotic signaling pathwayGO:00971911190.021
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.021
regulation of cell motilityGO:20001452990.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
regulation of cysteine type endopeptidase activityGO:20001161270.021
defense responseGO:00069523150.021
chromatin organizationGO:00063253510.021
purine nucleotide catabolic processGO:00061954050.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.021
small molecule biosynthetic processGO:00442831570.020
positive regulation of peptidase activityGO:0010952880.020
negative regulation of immune system processGO:00026831360.020
regulation of peptidase activityGO:00525471800.020
biological adhesionGO:00226103310.020
positive regulation of endopeptidase activityGO:0010950840.020
nervous system developmentGO:00073992930.020
regulation of mapk cascadeGO:00434082620.020
cellular response to light stimulusGO:0071482340.020
intracellular protein transportGO:00068862700.019
wnt signaling pathwayGO:00160551560.019
regulation of protein maturationGO:19033171500.019
positive regulation of immune system processGO:00026842830.019
memoryGO:000761330.019
regulation of protein kinase activityGO:00458592890.019
secretionGO:00469032540.019
positive regulation of purine nucleotide metabolic processGO:19005442270.018
nucleoside triphosphate metabolic processGO:00091414220.018
positive regulation of cell cycleGO:00457871400.018
activation of cysteine type endopeptidase activityGO:0097202570.018
secretion by cellGO:00329402260.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
negative regulation of protein modification processGO:00314002000.018
nucleoside monophosphate metabolic processGO:00091231910.018
locomotory behaviorGO:000762610.018
dna recombinationGO:0006310770.018
reactive oxygen species metabolic processGO:0072593750.018
organophosphate biosynthetic processGO:00904071630.018
rho protein signal transductionGO:0007266260.018
response to oxygen containing compoundGO:19017003690.017
negative regulation of hydrolase activityGO:00513461820.017
regulation of immune responseGO:00507762010.017
dephosphorylationGO:00163112090.017
regulation of myeloid leukocyte differentiationGO:0002761390.017
oxidation reduction processGO:00551143960.017
morphogenesis of embryonic epitheliumGO:001633140.017
negative regulation of proteolysisGO:00458611320.017
positive regulation of cysteine type endopeptidase activityGO:2001056790.017
protein modification by small protein removalGO:0070646920.017
regulation of cell growthGO:00015581350.017
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.017
cytokine productionGO:00018162470.017
carbohydrate derivative biosynthetic processGO:19011372070.017
regulation of cellular protein catabolic processGO:1903362960.017
translationGO:00064121320.016
protein oligomerizationGO:00512591730.016
organic acid biosynthetic processGO:0016053970.016
zymogen activationGO:0031638700.016
growthGO:00400072020.016
cell developmentGO:00484683280.016
ribonucleoside catabolic processGO:00424544060.016
g protein coupled receptor signaling pathwayGO:00071862070.016
viral processGO:00160321460.016
regenerationGO:003109940.016
organelle assemblyGO:00709251760.016
rhythmic behaviorGO:000762220.016
regulation of secretion by cellGO:19035301770.016
single organism cellular localizationGO:19025803320.016
ribonucleotide catabolic processGO:00092614050.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
positive regulation of nucleotide metabolic processGO:00459812300.016
regulation of anatomical structure morphogenesisGO:00226032860.016
cell adhesionGO:00071553250.016
regulation of protein processingGO:00706131500.016
adult locomotory behaviorGO:000834410.016
regulation of secretionGO:00510461940.016
endocytosisGO:00068971590.015
nitrogen compound transportGO:00717051910.015
oocyte differentiationGO:000999420.015
response to lipidGO:00339932060.015
angiogenesisGO:00015251470.015
regulation of nucleotide metabolic processGO:00061402690.015
cellular macromolecular complex assemblyGO:00346223240.015
regulation of purine nucleotide metabolic processGO:19005422640.015
cell morphogenesisGO:00009022960.015
cation transportGO:00068123310.015
rna processingGO:00063962550.015
embryonic epithelial tube formationGO:000183840.015
regulation of apoptotic signaling pathwayGO:20012331750.015
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720520.015
regulation of protein transportGO:00512232130.015
stem cell developmentGO:0048864690.015
cell growthGO:00160491600.015
transmembrane transportGO:00550853990.015
reproductive processGO:00224141060.015
cell projection organizationGO:00300302520.015
spermatid differentiationGO:004851540.015
interspecies interaction between organismsGO:00444191560.015
ion transmembrane transportGO:00342203380.015
stem cell divisionGO:001714520.014
regulation of nucleotide catabolic processGO:00308112050.014
nuclear transportGO:00511691790.014
positive regulation of mapk cascadeGO:00434101900.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.014
guanosine containing compound metabolic processGO:19010682440.014
organonitrogen compound biosynthetic processGO:19015662000.014
positive regulation of protein kinase activityGO:00458601900.014
metal ion transportGO:00300012720.014
gtp catabolic processGO:00061842370.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.014
glial cell migrationGO:000834740.014
gtp metabolic processGO:00460392390.014
posttranscriptional regulation of gene expressionGO:00106082130.014
negative regulation of phosphorylationGO:00423261740.014
cell cycle g1 s phase transitionGO:0044843800.014
positive regulation of phosphorylationGO:00423273940.014
cellular lipid metabolic processGO:00442553030.014
regulation of response to external stimulusGO:00321012220.014
positive regulation of protein phosphorylationGO:00019343130.014
neuroblast proliferationGO:000740540.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
response to other organismGO:00517072610.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
histone monoubiquitinationGO:0010390200.013
myeloid cell differentiationGO:00300991170.013
compound eye developmentGO:004874910.013
circulatory system developmentGO:00723592620.013
syncytium formation by plasma membrane fusionGO:000076820.013
response to growth factorGO:00708482050.013
single organism membrane organizationGO:00448022680.013
meiosis iGO:000712740.013
blastoderm segmentationGO:000735020.013
regulation of cell migrationGO:00303342890.013
divalent metal ion transportGO:00708381520.013
response to oxidative stressGO:00069791210.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
response to biotic stimulusGO:00096072760.013
actin filament based processGO:00300292240.013
spinal cord developmentGO:002151040.013
negative regulation of protein processingGO:00109551420.013
regulation of cellular component movementGO:00512703340.013
cellular component morphogenesisGO:00329893140.013
sensory perception of painGO:001923340.013
purine containing compound catabolic processGO:00725234110.013
purine ribonucleoside catabolic processGO:00461303980.013
positive regulation of cytokine productionGO:00018191670.013
negative regulation of cellular amine metabolic processGO:003323930.013
regulation of cytoskeleton organizationGO:00514931770.013
nuclear exportGO:0051168690.013
positive regulation of protein catabolic processGO:0045732750.013
positive regulation of nucleoside metabolic processGO:00459791860.013
neurogenesisGO:00220081690.013
meiotic chromosome segregationGO:004513240.013
purine ribonucleoside triphosphate metabolic processGO:00092054110.013
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.013
regulation of intracellular protein transportGO:00331571230.012
divalent inorganic cation transportGO:00725111580.012
positive regulation of transferase activityGO:00513472270.012
immune effector processGO:00022521590.012
monocarboxylic acid metabolic processGO:00327871850.012
regulation of nucleoside metabolic processGO:00091182090.012
carboxylic acid biosynthetic processGO:0046394970.012
protein homooligomerizationGO:00512601000.012
sequestering of metal ionGO:0051238240.012
cellular response to oxygen containing compoundGO:19017012760.012
positive regulation of cell differentiationGO:00455972110.012
positive regulation of organelle organizationGO:00106381950.012
cell activationGO:00017752130.012
positive regulation of cellular component organizationGO:00511303760.012
innate immune responseGO:00450871780.012
regulation of proteasomal protein catabolic processGO:0061136870.012
positive regulation of immune responseGO:00507781590.012
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.012
peripheral nervous system developmentGO:000742220.012
positive regulation of nucleotide catabolic processGO:00308131850.012
tube closureGO:006060630.012
regulation of leukocyte differentiationGO:1902105610.012
central nervous system developmentGO:00074171230.012
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204330.012
double strand break repairGO:00063021010.012
oocyte developmentGO:004859910.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
positive regulation of secretion by cellGO:19035321080.012
microtubule cytoskeleton organizationGO:00002261760.012
actin filament based movementGO:0030048170.012
reactive oxygen species biosynthetic processGO:190340940.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
inner ear morphogenesisGO:004247240.012
sequestering of calcium ionGO:0051208170.012
photoreceptor cell differentiationGO:004653020.012
regulation of response to dna damage stimulusGO:2001020940.012
regulation of ras protein signal transductionGO:00465781550.012
positive regulation of apoptotic signaling pathwayGO:2001235700.012
anatomical structure homeostasisGO:00602491000.012
negative regulation of protein maturationGO:19033181420.012
cellular carbohydrate metabolic processGO:0044262840.012
limbic system developmentGO:002176130.012
motor neuron axon guidanceGO:000804520.012
regulation of myeloid cell differentiationGO:0045637810.012
epithelial cell differentiationGO:00308551410.012
positive regulation of leukocyte activationGO:0002696800.012
regulation of epithelial cell proliferationGO:00506781130.012
glycoprotein metabolic processGO:00091001100.012
regulation of protein stabilityGO:0031647870.011
membrane organizationGO:00610242920.011
response to external biotic stimulusGO:00432072610.011
maintenance of locationGO:00512351120.011
nucleocytoplasmic transportGO:00069131760.011
positive regulation of cell migrationGO:00303351720.011
regulation of cytoplasmic transportGO:19036491490.011
positive regulation of secretionGO:00510471160.011
response to axon injuryGO:004867810.011
mitochondrion organizationGO:00070051560.011
negative regulation of cellular component movementGO:00512711060.011
neural tube closureGO:000184330.011
neuron developmentGO:00486661130.011
response to fungusGO:000962040.011
regulation of protein serine threonine kinase activityGO:00719001790.011
regulation of chromosome organizationGO:00330441030.011
i kappab kinase nf kappab signalingGO:00072491660.011
system processGO:00030083490.011
regulation of neural precursor cell proliferationGO:200017740.011
receptor mediated endocytosisGO:0006898840.011
response to inorganic substanceGO:00100351270.011
myeloid leukocyte differentiationGO:0002573600.011
positive regulation of kinase activityGO:00336742040.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.011
regulation of nucleocytoplasmic transportGO:0046822980.011
chromosome segregationGO:00070591140.011
hindbrain developmentGO:003090230.011
regulation of ion transportGO:00432691890.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
actin cytoskeleton organizationGO:00300362070.011
cell differentiation in spinal cordGO:002151510.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
positive regulation of protein transportGO:00512221350.011
microtubule organizing center organizationGO:0031023620.011
protein secretionGO:0009306980.011
calcium ion transportGO:00068161470.011
regulation of intracellular transportGO:00323861950.011
regulation of protein secretionGO:0050708860.011
endomembrane system organizationGO:00102561960.011
regulation of defense responseGO:00313471540.011
negative regulation of locomotionGO:00400131180.011
organ formationGO:004864530.011
multi organism cellular processGO:00447641560.011
regulation of viral processGO:00507921030.011
atp catabolic processGO:00062001570.011
neuromuscular junction developmentGO:000752830.011
cellular protein complex assemblyGO:00436231880.011
sleepGO:003043120.011
response to hormoneGO:00097251750.011
negative regulation of transportGO:00510511760.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
protein localization to organelleGO:00333652800.010
ion homeostasisGO:00508012300.010
cell type specific apoptotic processGO:00972851250.010
regulation of synaptic plasticityGO:004816730.010
protein targetingGO:00066051870.010
visual behaviorGO:000763220.010
peptidyl tyrosine phosphorylationGO:00181081700.010
peptidyl threonine modificationGO:0018210450.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
reactive nitrogen species metabolic processGO:200105730.010
organelle fissionGO:00482851490.010
regulation of leukocyte activationGO:00026941150.010
spermatid developmentGO:000728640.010
negative regulation of smoothened signaling pathwayGO:004587930.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
guanosine containing compound catabolic processGO:19010692390.010
negative regulation of cellular catabolic processGO:0031330830.010
cell proliferation in forebrainGO:002184610.010
regulation of protein complex assemblyGO:00432541470.010
single organism cell adhesionGO:00986021790.010
stress activated mapk cascadeGO:0051403930.010
positive regulation of locomotionGO:00400171860.010
chromatin assembly or disassemblyGO:0006333780.010
regulation of anatomical structure sizeGO:00900661010.010
response to woundingGO:00096111680.010
regulation of mitosisGO:0007088630.010
circadian behaviorGO:004851220.010
glycoprotein biosynthetic processGO:0009101910.010
anterior posterior axis specification embryoGO:000859520.010
positive regulation of intracellular transportGO:00323881040.010

DDB2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
xeroderma pigmentosumDOID:005042780.729
disease of metabolismDOID:00146672950.030
inherited metabolic disorderDOID:6552420.025
musculoskeletal system diseaseDOID:172230.024
disease of cellular proliferationDOID:145661740.022
organ system cancerDOID:00506861640.022
cancerDOID:1621670.022
sensory system diseaseDOID:00501552030.019
nervous system diseaseDOID:8634310.019
central nervous system diseaseDOID:3311860.017
muscular diseaseDOID:00800001140.016
muscle tissue diseaseDOID:661130.015
myopathyDOID:4231040.013
cardiovascular system diseaseDOID:12871060.013
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.013
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
brain diseaseDOID:936730.011
retinal diseaseDOID:56791180.011