Homo sapiens

86 known processes

DDB1

damage-specific DNA binding protein 1, 127kDa

(Aliases: XPCE,DDBA,XPE,XPE-BF,UV-DDB1,XAP1)

DDB1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin modificationGO:00165682980.986
cellular response to dna damage stimulusGO:00069743790.982
covalent chromatin modificationGO:00165692540.967
dna repairGO:00062811980.952
protein ubiquitinationGO:00165673140.947
cell competition in a multicellular organismGO:003521210.928
protein modification by small protein conjugationGO:00324463420.925
chromatin organizationGO:00063253510.913
peptidyl threonine phosphorylationGO:0018107410.891
cellular response to abiotic stimulusGO:00712141170.882
regulation of cell cycleGO:00517263930.851
cellular response to uvGO:0034644320.844
uv damage excision repairGO:007091470.832
regulation of mitotic cell cycle phase transitionGO:19019901180.785
regulation of cell cycle processGO:00105642660.773
dna damage checkpointGO:0000077680.701
growthGO:00400072020.695
response to uvGO:0009411730.603
somatic stem cell maintenanceGO:003501940.598
protein catabolic processGO:00301633250.598
regulation of growthGO:00400081650.585
histone h2a ubiquitinationGO:0033522170.584
response to light stimulusGO:0009416870.575
protein monoubiquitinationGO:0006513390.569
response to radiationGO:00093141510.558
cellular response to light stimulusGO:0071482340.533
proteolysis involved in cellular protein catabolic processGO:00516032440.493
mitotic dna damage checkpointGO:0044773280.481
mitotic cell cycle processGO:19030472860.461
regulation of mitotic cell cycleGO:00073461890.436
regulation of dna metabolic processGO:00510521530.435
response to abiotic stimulusGO:00096283360.410
histone phosphorylationGO:0016572160.404
mitotic cell cycle checkpointGO:0007093680.368
cell cycle phase transitionGO:00447701730.350
cellular response to radiationGO:0071478650.338
cellular macromolecule catabolic processGO:00442653800.333
cell cycle checkpointGO:00000751170.328
peptidyl threonine modificationGO:0018210450.309
cellular protein catabolic processGO:00442572610.300
regulation of response to dna damage stimulusGO:2001020940.293
protein modification by small protein removalGO:0070646920.289
modification dependent protein catabolic processGO:00199412090.281
double strand break repairGO:00063021010.274
histone h2a monoubiquitinationGO:0035518110.237
g1 s transition of mitotic cell cycleGO:0000082780.234
dna integrity checkpointGO:0031570710.227
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.226
regulation of g1 s transition of mitotic cell cycleGO:2000045400.225
single organism cellular localizationGO:19025803320.220
single organism carbohydrate metabolic processGO:00447231930.217
atp catabolic processGO:00062001570.199
mitotic sister chromatid segregationGO:0000070530.192
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.190
nucleoside monophosphate catabolic processGO:00091251590.183
mitotic cell cycle phase transitionGO:00447721620.174
regulation of cell cycle g1 s phase transitionGO:1902806420.170
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.166
ribonucleoside monophosphate catabolic processGO:00091581580.161
purine nucleotide catabolic processGO:00061954050.161
mitotic cell cycleGO:00002783260.158
modification dependent macromolecule catabolic processGO:00436322120.152
purine ribonucleoside monophosphate catabolic processGO:00091691580.141
negative regulation of cell differentiationGO:00455961710.130
proteasomal protein catabolic processGO:00104981760.127
purine ribonucleotide catabolic processGO:00091544040.125
nuclear divisionGO:00002801280.122
negative regulation of multicellular organismal processGO:00512413170.118
negative regulation of cell cycleGO:00457861930.118
ribonucleoside triphosphate catabolic processGO:00092033910.110
nucleoside triphosphate catabolic processGO:00091433940.110
nucleosome positioningGO:001658430.109
histone modificationGO:00165702510.104
regulation of cell cycle phase transitionGO:19019871260.103
positive regulation of cell cycle processGO:00900681060.103
purine ribonucleoside metabolic processGO:00461284370.100
histone h2a phosphorylationGO:199016430.100
regulation of protein catabolic processGO:00421761550.097
cell developmentGO:00484683280.094
atp metabolic processGO:00460341760.091
positive regulation of mitotic cell cycleGO:0045931600.089
cellular carbohydrate metabolic processGO:0044262840.087
positive regulation of cell cycleGO:00457871400.083
regulation of cellular response to stressGO:00801352440.082
positive regulation of proteasomal protein catabolic processGO:1901800350.081
posttranscriptional regulation of gene expressionGO:00106082130.078
protein autoubiquitinationGO:0051865370.077
myeloid cell differentiationGO:00300991170.076
regulation of cellular protein catabolic processGO:1903362960.076
negative regulation of cell cycle processGO:00109481210.075
cell cycle g1 s phase transitionGO:0044843800.074
protein localization to nucleusGO:00345041360.073
determination of adult lifespanGO:000834020.072
carbohydrate metabolic processGO:00059752070.070
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.069
multicellular organismal agingGO:001025930.068
regulation of proteasomal protein catabolic processGO:0061136870.066
nucleoside monophosphate metabolic processGO:00091231910.065
hemopoiesisGO:00300971800.064
mitotic dna integrity checkpointGO:0044774300.064
stem cell differentiationGO:0048863930.063
negative regulation of mitotic cell cycleGO:00459301020.063
protein deneddylationGO:0000338100.061
ubiquitin dependent protein catabolic processGO:00065112060.059
regulation of cell growthGO:00015581350.058
purine containing compound catabolic processGO:00725234110.058
negative regulation of leukocyte differentiationGO:1902106240.057
purine ribonucleoside triphosphate catabolic processGO:00092073910.057
stem cell developmentGO:0048864690.057
regulation of tor signalingGO:0032006300.057
positive regulation of cell proliferationGO:00082843010.056
histone monoubiquitinationGO:0010390200.056
regulation of proteolysisGO:00301622930.056
ribonucleoside monophosphate metabolic processGO:00091611870.055
protein polyubiquitinationGO:00002091100.055
microtubule based processGO:00070172100.054
immune system developmentGO:00025201950.053
nucleoside phosphate catabolic processGO:19012924120.051
regulation of myeloid cell differentiationGO:0045637810.051
positive regulation of protein catabolic processGO:0045732750.050
mapk cascadeGO:00001652880.050
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
nucleoside catabolic processGO:00091644080.049
regulation of dna repairGO:0006282470.049
leukocyte differentiationGO:0002521980.048
carbohydrate catabolic processGO:0016052360.047
positive regulation of proteolysisGO:00458621420.047
regulation of leukocyte differentiationGO:1902105610.047
embryo developmentGO:00097901230.047
Worm
purine nucleoside triphosphate metabolic processGO:00091444120.046
nucleotide catabolic processGO:00091664080.046
g2 dna damage checkpointGO:0031572260.045
purine nucleoside monophosphate metabolic processGO:00091261860.045
purine ribonucleoside monophosphate metabolic processGO:00091671860.045
cellular macromolecular complex assemblyGO:00346223240.043
positive regulation of protein transportGO:00512221350.043
purine nucleoside monophosphate catabolic processGO:00091281580.042
cullin deneddylationGO:001038890.041
cellular amino acid metabolic processGO:00065201160.040
negative regulation of mitotic cell cycle phase transitionGO:1901991850.040
double strand break repair via homologous recombinationGO:0000724500.039
protein deubiquitinationGO:0016579790.039
oocyte differentiationGO:000999420.038
purine ribonucleoside catabolic processGO:00461303980.038
glycosyl compound catabolic processGO:19016584130.038
regulation of locomotionGO:00400123290.037
mitotic g2 dna damage checkpointGO:000709570.037
monocarboxylic acid metabolic processGO:00327871850.037
cellular component disassemblyGO:0022411920.035
post embryonic developmentGO:000979120.035
Worm
intracellular protein transportGO:00068862700.035
negative regulation of cell proliferationGO:00082852280.034
mitotic g2 m transition checkpointGO:004481890.034
hematopoietic or lymphoid organ developmentGO:00485341860.033
negative regulation of cell deathGO:00605483450.033
Mouse
regulation of cell differentiationGO:00455953930.033
apoptotic signaling pathwayGO:00971902680.032
regulation of protein stabilityGO:0031647870.032
female gamete generationGO:000729220.031
negative regulation of immune system processGO:00026831360.031
organophosphate catabolic processGO:00464344300.031
nervous system developmentGO:00073992930.031
negative regulation of cell cycle phase transitionGO:1901988890.030
cellular response to endogenous stimulusGO:00714953360.030
cell divisionGO:00513011680.029
cellular protein complex assemblyGO:00436231880.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
positive regulation of growthGO:0045927580.029
sister chromatid segregationGO:0000819540.029
dna recombinationGO:0006310770.029
blastoderm segmentationGO:000735020.029
histone ubiquitinationGO:0016574310.028
negative regulation of proteolysisGO:00458611320.028
negative regulation of protein metabolic processGO:00512483910.028
negative regulation of granulocyte differentiationGO:003085350.028
protein targetingGO:00066051870.027
regulation of cellular ketone metabolic processGO:0010565500.027
regulation of cell motilityGO:20001452990.027
small molecule biosynthetic processGO:00442831570.027
protein stabilizationGO:0050821640.027
regulation of transferase activityGO:00513383550.027
nuclear transportGO:00511691790.027
negative regulation of catalytic activityGO:00430863350.027
reproductionGO:0000003630.027
Worm
protein maturationGO:00516042330.027
regulation of chromosome organizationGO:00330441030.027
reactive oxygen species metabolic processGO:0072593750.027
cellular amine metabolic processGO:0044106410.027
regulation of dna damage checkpointGO:200000190.026
cytoplasmic transportGO:00164823790.026
regulation of establishment of protein localizationGO:00702012420.026
neuron differentiationGO:00301821380.026
positive regulation of catabolic processGO:00098963100.026
purine nucleoside catabolic processGO:00061523980.025
rna interferenceGO:001624640.025
regulation of myeloid leukocyte differentiationGO:0002761390.025
cell activationGO:00017752130.025
locomotory behaviorGO:000762610.024
endocytosisGO:00068971590.024
Worm
ribonucleotide catabolic processGO:00092614050.024
segmentationGO:003528240.024
regulation of cytoplasmic transportGO:19036491490.024
ribonucleoside catabolic processGO:00424544060.024
macromolecular complex disassemblyGO:0032984600.024
vesicle mediated transportGO:00161923710.024
Worm
regulation of protein maturationGO:19033171500.023
negative regulation of apoptotic processGO:00430663160.023
Mouse
positive regulation of mitotic cell cycle phase transitionGO:1901992190.023
negative regulation of proteasomal protein catabolic processGO:1901799320.023
oogenesisGO:004847720.023
protein processingGO:00164852260.023
mitotic nuclear divisionGO:00070671190.022
lipid localizationGO:00108761060.022
positive regulation of developmental processGO:00510943140.022
signal transduction by phosphorylationGO:00230142970.021
cell cycle arrestGO:0007050710.021
regulation of protein processingGO:00706131500.021
methylationGO:00322591060.021
positive regulation of nucleocytoplasmic transportGO:0046824540.021
nucleoside triphosphate metabolic processGO:00091414220.021
regenerationGO:003109940.021
regulation of carbohydrate metabolic processGO:0006109540.021
lipid biosynthetic processGO:00086101770.021
cell projection organizationGO:00300302520.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of intracellular protein transportGO:00331571230.021
negative regulation of catabolic processGO:00098951040.020
glial cell migrationGO:000834740.020
cytokinesisGO:0000910960.020
myeloid leukocyte differentiationGO:0002573600.020
developmental process involved in reproductionGO:0003006660.020
Worm
macromolecule methylationGO:0043414970.020
single organism nuclear importGO:19025931040.019
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.019
regulation of intracellular transportGO:00323861950.019
dna geometric changeGO:0032392320.019
negative regulation of cellular protein catabolic processGO:1903363380.019
negative regulation of myeloid leukocyte differentiationGO:0002762160.018
anatomical structure homeostasisGO:00602491000.018
positive regulation of phosphorylationGO:00423273940.018
microtubule cytoskeleton organizationGO:00002261760.018
negative regulation of intracellular signal transductionGO:19025321830.018
cellular component morphogenesisGO:00329893140.018
positive regulation of protein import into nucleusGO:0042307460.018
cell cell signalingGO:00072671550.018
development of primary sexual characteristicsGO:0045137350.018
Worm
nucleotide excision repairGO:0006289310.018
nucleosome organizationGO:0034728660.018
response to ionizing radiationGO:0010212650.018
cell growthGO:00160491600.018
regulation of nucleocytoplasmic transportGO:0046822980.018
generation of neuronsGO:00486991520.018
neuron developmentGO:00486661130.018
negative regulation of phosphorus metabolic processGO:00105632670.018
negative regulation of protein maturationGO:19033181420.018
neurogenesisGO:00220081690.018
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.017
regulation of cellular component movementGO:00512703340.017
gonad developmentGO:0008406340.017
Worm
regulation of dna replicationGO:0006275680.017
organelle fissionGO:00482851490.017
oocyte developmentGO:004859910.017
nuclear importGO:00511701060.017
organic acid biosynthetic processGO:0016053970.017
signal transduction by p53 class mediatorGO:0072331720.017
regulation of cellular amino acid metabolic processGO:000652160.017
protein import into nucleusGO:00066061040.017
histone exchangeGO:004348630.016
sex differentiationGO:0007548450.016
Worm
oxidation reduction processGO:00551143960.016
regulation of protein modification by small protein conjugation or removalGO:19033201070.016
positive regulation of intracellular transportGO:00323881040.016
generation of precursor metabolites and energyGO:0006091680.016
lipid metabolic processGO:00066293810.016
circulatory system developmentGO:00723592620.016
positive regulation of apoptotic processGO:00430652460.015
establishment of protein localization to organelleGO:00725941720.015
cell morphogenesisGO:00009022960.015
single organism carbohydrate catabolic processGO:0044724330.015
response to woundingGO:00096111680.015
immune responseGO:00069553070.015
multicellular organism reproductionGO:0032504420.015
Worm
regulation of granulocyte differentiationGO:0030852110.015
regulation of peptidase activityGO:00525471800.015
molting cycleGO:0042303280.015
negative regulation of phosphorylationGO:00423261740.015
biological adhesionGO:00226103310.015
regulation of cytokine productionGO:00018172320.014
positive regulation of dna metabolic processGO:0051054730.014
regulation of cellular amine metabolic processGO:0033238110.014
positive regulation of intracellular protein transportGO:0090316760.014
negative regulation of protein processingGO:00109551420.014
citrate metabolic processGO:000610120.014
negative regulation of protein catabolic processGO:0042177590.014
neuron projection developmentGO:00311751060.014
positive regulation of cytoplasmic transportGO:1903651820.014
reproductive system developmentGO:0061458560.014
Worm
positive regulation of cell deathGO:00109422630.014
positive regulation of programmed cell deathGO:00430682490.014
positive regulation of hydrolase activityGO:00513453310.013
tube developmentGO:00352951250.013
single organism reproductive processGO:0044702980.013
Worm
regulation of protein serine threonine kinase activityGO:00719001790.013
histone methylationGO:0016571600.013
metencephalon developmentGO:002203720.013
protein targeting to nucleusGO:00447441040.013
positive regulation of cellular amine metabolic processGO:003324070.013
regulation of kinase activityGO:00435493140.013
negative regulation of myeloid cell differentiationGO:0045638420.013
protein acylationGO:00435431380.013
protein dna complex subunit organizationGO:0071824800.013
response to hormoneGO:00097251750.013
regulation of gene expression epigeneticGO:0040029730.013
protein methylationGO:0006479740.013
telomere maintenanceGO:0000723320.013
regulation of mapk cascadeGO:00434082620.013
tissue regenerationGO:004224630.013
peripheral nervous system developmentGO:000742220.013
dephosphorylationGO:00163112090.013
autophagyGO:0006914880.013
peptidyl lysine modificationGO:00182051440.012
jnk cascadeGO:0007254800.012
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435300.012
regulation of cellular carbohydrate metabolic processGO:0010675470.012
chromatin remodelingGO:0006338550.012
cell adhesionGO:00071553250.012
eye photoreceptor cell differentiationGO:000175420.012
epithelium developmentGO:00604292270.012
positive regulation of cellular protein catabolic processGO:1903364370.012
response to decreased oxygen levelsGO:0036293960.012
negative regulation of cellular component movementGO:00512711060.012
photoreceptor cell differentiationGO:004653020.012
hematopoietic stem cell differentiationGO:006021840.012
positive regulation of nucleotide metabolic processGO:00459812300.012
negative regulation of cellular catabolic processGO:0031330830.012
reproductive structure developmentGO:0048608550.012
Worm
secretion by cellGO:00329402260.012
pyruvate metabolic processGO:0006090260.012
negative regulation of growthGO:0045926970.012
regulation of meiotic cell cycleGO:005144540.012
compound eye developmentGO:004874910.012
telomere maintenance via recombinationGO:000072240.012
cellular response to organonitrogen compoundGO:00714171240.011
positive regulation of transcription factor import into nucleusGO:0042993250.011
negative regulation of protein modification processGO:00314002000.011
negative regulation of developmental processGO:00510932470.011
regulation of lipid biosynthetic processGO:0046890470.011
spermatid differentiationGO:004851540.011
glycolytic processGO:0006096170.011
embryonic epithelial tube formationGO:000183840.011
cell projection morphogenesisGO:00488581290.011
positive regulation of cellular catabolic processGO:00313312840.011
positive regulation of transportGO:00510503360.011
adult locomotory behaviorGO:000834410.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.011
cellular ketone metabolic processGO:0042180800.011
embryonic morphogenesisGO:0048598850.011
negative regulation of transportGO:00510511760.011
response to starvationGO:0042594590.011
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.011
negative regulation of neuron deathGO:1901215320.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
translationGO:00064121320.010
extrinsic apoptotic signaling pathwayGO:00971911190.010
amine metabolic processGO:0009308440.010
cardiac muscle cell contractionGO:008600340.010
positive regulation of protein phosphorylationGO:00019343130.010
positive regulation of cytokine productionGO:00018191670.010
chromatin assemblyGO:0031497610.010
stress activated mapk cascadeGO:0051403930.010
gene silencingGO:0016458490.010
neurological system processGO:00508771630.010
visual behaviorGO:000763220.010
reproductive processGO:00224141060.010
Worm

DDB1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
xeroderma pigmentosumDOID:005042780.251
sensory system diseaseDOID:00501552030.028
eye and adnexa diseaseDOID:14921500.028
nervous system diseaseDOID:8634310.028
retinal diseaseDOID:56791180.028
eye diseaseDOID:56141490.028
neurodegenerative diseaseDOID:12891020.024
central nervous system diseaseDOID:3311860.024
disease of metabolismDOID:00146672950.012
muscular diseaseDOID:00800001140.011
musculoskeletal system diseaseDOID:172230.011
muscle tissue diseaseDOID:661130.011