Homo sapiens

78 known processes

SMAD1

SMAD family member 1

(Aliases: BSP1,JV41,MADH1,MADR1,JV4-1)

SMAD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of activin receptor signaling pathwayGO:0032925141.000
Human
response to host defensesGO:005220021.000
Human
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152221.000
Mouse
zygotic specification of dorsal ventral axisGO:000735221.000
Human
hard palate developmentGO:006002211.000
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325731.000
positive regulation of mesoderm developmentGO:200038221.000
Human
regulation of mesoderm developmentGO:200038041.000
Human
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015481.000
Human
response to hostGO:007513621.000
Human
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016411.000
Human
negative regulation of pathway restricted smad protein phosphorylationGO:0060394111.000
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.999
Human
nodal signaling pathway involved in determination of left right asymmetryGO:003810710.999
Human
activin receptor signaling pathwayGO:0032924240.999
Human
avoidance of host defensesGO:004441320.999
Human
bmp signaling pathwayGO:0030509490.999
evasion or tolerance of host defensesGO:004441520.999
Human
positive regulation of bmp signaling pathwayGO:003051390.998
Human
pathway restricted smad protein phosphorylationGO:0060389380.998
Human
mesonephros developmentGO:0001823170.998
Mouse
negative regulation of transcription by competitive promoter bindingGO:001094480.997
Human
response to defenses of other organism involved in symbiotic interactionGO:005217320.997
Human
enzyme linked receptor protein signaling pathwayGO:00071673030.997
regulation of stem cell differentiationGO:2000736560.997
Human
mesenchymal cell developmentGO:0014031500.996
Human
cellular response to endogenous stimulusGO:00714953360.996
Human Mouse Fly
transforming growth factor beta receptor signaling pathwayGO:0007179760.996
Human Fly
mesenchyme developmentGO:0060485590.996
Human
ureteric bud developmentGO:0001657130.996
Mouse
negative regulation of peptidyl threonine phosphorylationGO:001080160.996
Human
cellular response to growth factor stimulusGO:00713631970.996
Human Mouse Fly
cellular response to transforming growth factor beta stimulusGO:0071560940.995
Human Fly
positive regulation of transcription factor import into nucleusGO:0042993250.994
Human
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512280.993
Human
avoidance of defenses of other organism involved in symbiotic interactionGO:005183220.993
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.992
Human
cell cycle arrestGO:0007050710.992
Human
determination of left right asymmetry in lateral mesodermGO:000314010.992
Human
transforming growth factor beta productionGO:0071604140.992
Human
negative regulation of cellular response to growth factor stimulusGO:0090288410.991
Human
stem cell differentiationGO:0048863930.989
Human Fly
viral processGO:00160321460.989
Human
lateral mesoderm developmentGO:004836810.988
Human
regulation of cell cycleGO:00517263930.987
Human Worm Fly
regulation of epithelial to mesenchymal transitionGO:0010717370.986
Human
multi organism cellular processGO:00447641560.986
Human
positive regulation of osteoblast differentiationGO:0045669230.986
Mouse
regulation of pathway restricted smad protein phosphorylationGO:0060393340.986
Human
kidney epithelium developmentGO:0072073250.985
Mouse
negative regulation of cell differentiationGO:00455961710.985
Fly
modulation by virus of host morphology or physiologyGO:0019048100.984
Human
positive regulation of stem cell differentiationGO:2000738290.984
Human
negative regulation of peptidyl serine phosphorylationGO:003313780.982
Human
positive regulation of proteasomal protein catabolic processGO:1901800350.982
Human
regulation of canonical wnt signaling pathwayGO:0060828880.980
Human
positive regulation of cellular protein catabolic processGO:1903364370.980
Human
common partner smad protein phosphorylationGO:000718230.979
Human
evasion or tolerance of host defenses by virusGO:001904920.979
Human
response to cholesterolGO:0070723110.979
Human
circulatory system developmentGO:00723592620.977
Mouse
regulation of cellular response to growth factor stimulusGO:0090287760.976
Human
epithelial to mesenchymal transitionGO:0001837480.976
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.972
Human
regulation of bmp signaling pathwayGO:0030510270.970
Human
negative regulation of ligase activityGO:005135280.970
Human
regulation of mrna export from nucleusGO:001079330.970
positive regulation of protein catabolic processGO:0045732750.969
Human
response to growth factorGO:00708482050.969
Human Mouse Fly
negative regulation of ubiquitin protein transferase activityGO:005144480.966
Human
regulation of meiotic cell cycleGO:005144540.963
Worm
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.962
Human
regulation of proteasomal protein catabolic processGO:0061136870.961
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.961
regulation of ubiquitin protein transferase activityGO:0051438280.961
Human
negative regulation of bmp signaling pathwayGO:0030514170.961
Human
evasion or tolerance of defenses of other organism involved in symbiotic interactionGO:005183420.958
Human
peptidyl threonine phosphorylationGO:0018107410.957
Human
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009410.957
Human
negative regulation of cell proliferationGO:00082852280.957
Human Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.956
Human
endodermal cell fate commitmentGO:000171140.955
Fly
positive regulation of cell deathGO:00109422630.955
Human
negative regulation of sodium ion transmembrane transporter activityGO:200065020.953
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.952
Human
mesenchymal cell differentiationGO:0048762520.950
Human
regulation of cytokine productionGO:00018172320.950
Human
regulation of isoprenoid metabolic processGO:001974710.946
positive regulation of proteolysisGO:00458621420.945
Human
positive regulation of programmed cell deathGO:00430682490.943
Human
regulation of transferase activityGO:00513383550.943
Human
negative regulation of cell cycleGO:00457861930.942
Human Worm Fly
mesonephric tubule developmentGO:0072164140.939
Mouse
negative regulation of sodium ion transmembrane transportGO:190230620.938
negative regulation of developmental processGO:00510932470.936
Fly
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.933
Human
negative regulation of smad protein complex assemblyGO:001099140.931
Human
vasculature developmentGO:00019441810.927
transmission of virusGO:001908910.926
regulation of sequence specific dna binding transcription factor activityGO:00510902110.925
Human
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.925
Human Rat
endodermal cell fate specificationGO:000171440.917
Fly
regulation of nodal signaling pathwayGO:190010710.916
Human
cardiac muscle tissue developmentGO:0048738390.915
Mouse
positive regulation of protein import into nucleusGO:0042307460.914
Human
regulation of establishment of protein localizationGO:00702012420.914
Human
interaction with hostGO:0051701420.913
Human
regulation of cell differentiationGO:00455953930.910
Human Mouse Rat Fly
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190017510.905
Human
dorsal ventral pattern formationGO:0009953150.900
Human Zebrafish
response to transforming growth factor betaGO:0071559940.899
Human Fly
positive regulation of apoptotic processGO:00430652460.898
Human
intraciliary transportGO:004207370.897
endocardial cushion developmentGO:000319730.893
neuromuscular junction developmentGO:000752830.891
Fly
development involved in symbiotic interactionGO:004411110.888
positive regulation of developmental processGO:00510943140.884
Human Mouse Rat Worm Fly
cardiovascular system developmentGO:00723582620.884
Mouse
negative regulation of phosphorus metabolic processGO:00105632670.880
Human
regulation of protein ubiquitinationGO:0031396950.877
Human
regulation of endopeptidase activityGO:00525481700.876
Human
ubiquitin dependent endocytosisGO:007008610.875
positive regulation of intracellular protein transportGO:0090316760.874
Human
regulation of nodal signaling pathway involved in determination of left right asymmetryGO:190014510.870
Human
positive regulation of peptidase activityGO:0010952880.870
Human
negative regulation of cell fate specificationGO:000999630.868
regulation of protein modification by small protein conjugation or removalGO:19033201070.867
Human
smad protein signal transductionGO:0060395100.867
Human
trna transportGO:005103110.857
regulation of ligase activityGO:0051340290.856
Human
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122830.853
positive regulation of epithelial to mesenchymal transitionGO:0010718220.852
Human
negative regulation of muscle organ developmentGO:0048635120.845
positive regulation of canonical wnt signaling pathwayGO:0090263330.840
Human
regulation of peptidase activityGO:00525471800.838
Human
regulation of cell morphogenesis involved in differentiationGO:0010769830.837
Human Rat
response to decreased oxygen levelsGO:0036293960.835
Human
positive regulation of nucleocytoplasmic transportGO:0046824540.835
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.833
Human
myeloid cell differentiationGO:00300991170.830
Zebrafish
positive regulation of endopeptidase activityGO:0010950840.822
Human
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.821
Human
stem cell maintenanceGO:0019827190.820
Fly
activation of cysteine type endopeptidase activityGO:0097202570.814
Human
trna export from nucleusGO:000640910.810
regulation of cell cell adhesionGO:0022407570.803
Human
canonical wnt signaling pathwayGO:00600701160.802
Human
negative regulation of mitotic cell cycleGO:00459301020.802
Human Worm Fly
retinal ganglion cell axon guidanceGO:003129020.800
protein targeting to nucleusGO:00447441040.798
Human
regulation of muscle organ developmentGO:0048634270.798
response to other organismGO:00517072610.797
Human
regulation of osteoblast differentiationGO:0045667380.791
Mouse
somatic stem cell maintenanceGO:003501940.790
Fly
embryonic heart tube morphogenesisGO:000314380.789
protein localization to organelleGO:00333652800.787
Human
transforming growth factor beta2 productionGO:003290660.787
Human
cellular macromolecule catabolic processGO:00442653800.783
Human
regulation of muscle system processGO:0090257530.782
regulation of smad protein complex assemblyGO:001099040.779
Human
negative regulation of cell fate commitmentGO:001045430.778
regulation of transcription factor import into nucleusGO:0042990390.778
Human
heart morphogenesisGO:0003007480.777
ubiquitin dependent protein catabolic processGO:00065112060.774
Human
response to fluid shear stressGO:0034405140.772
Human
nucleocytoplasmic transportGO:00069131760.772
Human
smad protein complex assemblyGO:0007183120.771
establishment of protein localization to organelleGO:00725941720.771
Human
regulation of cellular component biogenesisGO:00440872810.767
Human Fly
embryonic morphogenesisGO:0048598850.766
Mouse Fly
single organismal cell cell adhesionGO:00163371480.763
Human
tissue migrationGO:00901301190.762
mesonephric epithelium developmentGO:0072163140.755
Mouse
muscle system processGO:0003012810.747
protein modification by small protein conjugationGO:00324463420.743
Human
protein localization to nucleusGO:00345041360.741
Human
positive regulation of cell differentiationGO:00455972110.737
Human Mouse Rat
regulation of transforming growth factor beta productionGO:0071634130.736
Human
response to lipidGO:00339932060.733
Human
regulation of alkaline phosphatase activityGO:001069220.729
negative regulation of protein phosphorylationGO:00019331400.728
Human
growthGO:00400072020.717
Human Mouse Worm Fly
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.709
Human
regulation of cellular protein catabolic processGO:1903362960.709
Human
polyprenol biosynthetic processGO:001609410.705
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190022410.702
Human
amine metabolic processGO:0009308440.701
nervous system developmentGO:00073992930.700
Mouse Rat Fly
positive regulation of protein transportGO:00512221350.698
Human
organ formationGO:004864530.696
cell projection organizationGO:00300302520.695
Rat
cell junction assemblyGO:0034329670.694
Human
cellular component morphogenesisGO:00329893140.693
Human Rat
positive regulation of protein ubiquitinationGO:0031398530.685
Human
modification by symbiont of host morphology or physiologyGO:0044003120.680
Human
nodal signaling pathwayGO:003809250.679
Human
polyprenol metabolic processGO:001609330.673
regulation of nucleocytoplasmic transportGO:0046822980.671
Human
response to abiotic stimulusGO:00096283360.668
Human
dorsal ventral axis specificationGO:000995070.667
Human
positive regulation of cytoplasmic transportGO:1903651820.667
Human
negative regulation of cell growthGO:0030308830.663
Human
adherens junction organizationGO:0034332360.662
Human
peptidyl threonine modificationGO:0018210450.660
Human
negative regulation of striated muscle tissue developmentGO:0045843110.660
response to organic cyclic compoundGO:00140702040.658
Human Mouse
stem cell divisionGO:001714520.657
Fly
positive regulation of cellular catabolic processGO:00313312840.650
Human
regulation of growthGO:00400081650.648
Human Worm Fly
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.646
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.643
Human
regulation of cell morphogenesisGO:00226041530.643
Human Rat
mesoderm developmentGO:0007498140.639
Human Mouse
proteasomal protein catabolic processGO:00104981760.632
Human
ribosomal large subunit export from nucleusGO:000005530.630
kidney developmentGO:0001822530.628
Mouse Rat
positive regulation of protein phosphorylationGO:00019343130.619
protein complex localizationGO:0031503310.619
Human
regulation of nervous system developmentGO:0051960880.617
Rat Fly
blood vessel developmentGO:00015681720.615
protein import into nucleusGO:00066061040.612
Human
cell adhesionGO:00071553250.612
Human
immune responseGO:00069553070.611
Human
cell part morphogenesisGO:00329901370.603
Rat
mitotic cell cycleGO:00002783260.599
Human Worm Fly
regulation of anatomical structure morphogenesisGO:00226032860.598
Human Rat
positive regulation of catabolic processGO:00098963100.596
Human
cytokine productionGO:00018162470.595
Human
cellular amino acid metabolic processGO:00065201160.593
negative regulation of sodium ion transportGO:001076630.590
cellular amine metabolic processGO:0044106410.590
response to external biotic stimulusGO:00432072610.589
Human
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.587
Human
cell morphogenesisGO:00009022960.585
Human Rat
extrinsic apoptotic signaling pathwayGO:00971911190.584
Human
catenin import into nucleusGO:0035411180.584
Human
regulation of cysteine type endopeptidase activityGO:20001161270.583
Human
regulation of protein catabolic processGO:00421761550.583
Human
regulation of protein serine threonine kinase activityGO:00719001790.579
regulation of endothelial cell migrationGO:0010594670.578
negative regulation of catalytic activityGO:00430863350.576
Human
regulation of ribosome biogenesisGO:009006910.576
muscle structure developmentGO:0061061980.575
regulation of cell developmentGO:00602841610.571
Human Rat
chromatin organizationGO:00063253510.569
otic vesicle developmentGO:007159910.567
regulation of smooth muscle cell differentiationGO:005115030.564
regulation of cellular amine metabolic processGO:0033238110.561
positive regulation of wnt signaling pathwayGO:0030177540.556
Human
regulation of cartilage developmentGO:0061035120.555
Mouse
nuclear importGO:00511701060.552
Human
embryonic axis specificationGO:000057850.551
Human
response to biotic stimulusGO:00096072760.550
Human
peptidyl serine modificationGO:00182091060.550
Human
tube morphogenesisGO:0035239950.549
Mouse Fly
response to oxygen levelsGO:00704821000.541
Human
protein targetingGO:00066051870.534
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.532
Human
determination of bilateral symmetryGO:0009855150.532
Human
dissemination or transmission of symbiont from hostGO:004400710.527
blood vessel morphogenesisGO:00485141620.527
regulation of ketone biosynthetic processGO:001056670.524
stem cell developmentGO:0048864690.524
Human Fly
cell morphogenesis involved in differentiationGO:00009041440.524
Human Rat
negative regulation of catabolic processGO:00098951040.520
Human
cellular response to bmp stimulusGO:007177380.518
Mouse
anatomical structure formation involved in morphogenesisGO:00486462840.517
Mouse Fly
endosome transport via multivesicular body sorting pathwayGO:003250930.515
regulation of protein localizationGO:00328802960.514
Human
zymogen activationGO:0031638700.513
Human
regulation of protein import into nucleusGO:0042306780.512
Human
regulation of catenin import into nucleusGO:0035412180.510
Human
cell fate commitmentGO:0045165270.507
Mouse Fly
regulation of protein transportGO:00512232130.507
Human
negative regulation of protein modification processGO:00314002000.503
Human
dissemination or transmission of organism from other organism involved in symbiotic interactionGO:005182110.502
regulation of system processGO:00440571010.500
negative regulation of multicellular organismal processGO:00512413170.500
organ morphogenesisGO:00098871470.499
Fly
ameboidal type cell migrationGO:00016671350.499
positive regulation of cell developmentGO:0010720920.492
Human Rat
positive regulation of transcription via serum response element bindingGO:001073530.490
regulation of cellular ketone metabolic processGO:0010565500.486
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.485
cell migration involved in gastrulationGO:004207410.484
positive regulation of hydrolase activityGO:00513453310.481
Human
atrioventricular valve developmentGO:000317130.479
response to oxygen containing compoundGO:19017003690.473
Human
gland developmentGO:0048732480.472
mitotic cell cycle phase transitionGO:00447721620.464
Fly
digestive tract morphogenesisGO:0048546560.460
Mouse Fly
muscle cell fate commitmentGO:004269340.454
positive regulation of cysteine type endopeptidase activityGO:2001056790.453
Human
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325630.451
negative regulation of gliogenesisGO:001401430.449
negative regulation of cell cycle g1 s phase transitionGO:1902807290.449
Fly
striated muscle tissue developmentGO:0014706590.442
Mouse
potassium ion transportGO:0006813620.435
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076710.435
extraocular skeletal muscle developmentGO:000207410.430
dolichol biosynthetic processGO:001940810.428
negative regulation of growthGO:0045926970.428
Human
specification of symmetryGO:0009799160.410
Human
regulation of rrna processingGO:200023210.409
protein ubiquitinationGO:00165673140.407
Human
chemotaxisGO:00069351570.406
Fly
endoderm formationGO:0001706330.403
Fly
quinone biosynthetic processGO:190166360.403
negative regulation of cellular amine metabolic processGO:003323930.402
positive regulation of intracellular transportGO:00323881040.402
Human
protein importGO:00170381300.402
Human
epithelium developmentGO:00604292270.399
Mouse Fly
response to alcoholGO:0097305640.398
Human
negative regulation of glial cell proliferationGO:006025320.389
regulation of intracellular transportGO:00323861950.387
Human
pattern specification processGO:0007389430.386
Human Zebrafish Fly
cellular ketone metabolic processGO:0042180800.385
negative regulation of cellular amino acid metabolic processGO:004576320.383
epithelial cell differentiationGO:00308551410.382
Fly
sodium ion transmembrane transportGO:0035725590.380
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076810.379
regulation of cell cycle processGO:00105642660.378
Fly
intracellular protein transportGO:00068862700.378
Human
modification dependent protein catabolic processGO:00199412090.370
Human
neuron differentiationGO:00301821380.368
Rat
positive regulation of map kinase activityGO:0043406800.368
positive regulation of catenin import into nucleusGO:003541390.363
Human
rrna containing ribonucleoprotein complex export from nucleusGO:007142840.359
single organism nuclear importGO:19025931040.358
Human
negative regulation of phosphorylationGO:00423261740.358
Human
determination of left right symmetryGO:0007368110.357
Human
regulation of synapse assemblyGO:005196350.355
Fly
modification dependent macromolecule catabolic processGO:00436322120.354
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.353
Human
regulation of epithelial cell proliferationGO:00506781130.350
intracellular steroid hormone receptor signaling pathwayGO:0030518610.349
regulation of peptidyl serine phosphorylationGO:0033135500.348
Human
mapk cascadeGO:00001652880.339
Mouse Rat
cell developmentGO:00484683280.333
Human Zebrafish Rat Fly
cell substrate adhesionGO:00315891320.329
Human
erythrocyte differentiationGO:0030218280.326
regulation of cell adhesionGO:00301551660.325
Human
adherens junction assemblyGO:0034333340.324
Human
positive regulation of cellular component organizationGO:00511303760.322
Human Rat Fly
bone developmentGO:0060348260.321
Mouse
fat cell differentiationGO:0045444320.321
Human
regulation of epithelial cell migrationGO:0010632930.320
regulation of intracellular protein transportGO:00331571230.311
Human
regulation of protein kinase activityGO:00458592890.309
interspecies interaction between organismsGO:00444191560.307
Human
cell proliferation involved in heart valve developmentGO:200079310.306
cell junction organizationGO:0034330790.305
Human
cellular protein complex localizationGO:003462980.303
Human
progesterone receptor signaling pathwayGO:005084730.302
neuron fate commitmentGO:004866320.302
blastoderm segmentationGO:000735020.301
Fly
connective tissue developmentGO:0061448390.300
Mouse
generation of neuronsGO:00486991520.294
Rat
negative regulation of protein catabolic processGO:0042177590.294
Human
positive regulation of cell cell adhesionGO:0022409220.292
Human
single organism cellular localizationGO:19025803320.287
Human
cellular protein complex assemblyGO:00436231880.283
heart developmentGO:0007507950.278
Mouse
compound eye developmentGO:004874910.276
Fly
negative regulation of apoptotic processGO:00430663160.274
Human Rat
protein catabolic processGO:00301633250.269
Human
monovalent inorganic cation transportGO:00156721280.269
endodermal cell differentiationGO:0035987310.267
Fly
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.265
endothelial cell migrationGO:0043542860.262
response to laminar fluid shear stressGO:003461680.260
Human
positive regulation of transportGO:00510503360.254
Human
negative regulation of cellular component organizationGO:00511292350.252
Human
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.251
Human
dephosphorylationGO:00163112090.250
lens morphogenesis in camera type eyeGO:000208920.249
chordate embryonic developmentGO:0043009340.248
intracellular receptor signaling pathwayGO:00305221040.248
regulation of mapk cascadeGO:00434082620.247
pharynx developmentGO:006046510.244
positive regulation of mapk cascadeGO:00434101900.244
cardiac chamber developmentGO:0003205300.242
histone h4 k12 acetylationGO:004398360.241
cardiac muscle contractionGO:0060048340.238
heart valve formationGO:000318820.234
epidermal cell differentiationGO:0009913450.233
cell cell junction organizationGO:0045216690.233
Human
angiogenesisGO:00015251470.231
regulation of immune responseGO:00507762010.228
nuclear transportGO:00511691790.227
Human
negative regulation of cell developmentGO:0010721480.227
regulation of protein stabilityGO:0031647870.226
Human
cell fate specificationGO:000170880.223
Fly
regulation of peptidyl threonine phosphorylationGO:0010799150.219
Human
embryonic heart tube developmentGO:003505090.216
cardiocyte differentiationGO:0035051230.215
regulation of mitotic cell cycleGO:00073461890.213
Human Worm Fly
embryonic organ morphogenesisGO:0048562240.212
muscle contractionGO:0006936730.210
convergent extensionGO:006002610.208
protein maturationGO:00516042330.208
Human
ventricular septum morphogenesisGO:006041230.207
embryonic hemopoiesisGO:003516240.207
tube developmentGO:00352951250.204
Mouse Fly
negative regulation of transferase activityGO:00513481240.204
Human
response to sterolGO:0036314140.203
Human
negative regulation of programmed cell deathGO:00430693210.202
Human Rat
biological adhesionGO:00226103310.201
Human
negative regulation of protein ubiquitinationGO:0031397350.200
Human
ectodermal cell fate specificationGO:000171510.199
regulation of kinase activityGO:00435493140.199
regulation of transforming growth factor beta2 productionGO:003290960.198
Human
negative regulation of phosphate metabolic processGO:00459362670.198
Human
response to hypoxiaGO:0001666960.196
Human
negative regulation of beta amyloid clearanceGO:190022230.196
regulation of protein localization to nucleusGO:1900180850.196
Human
convergent extension involved in gastrulationGO:006002710.194
urogenital system developmentGO:0001655650.194
Mouse Rat Fly
positive regulation of activin receptor signaling pathwayGO:003292760.194
Human
regulation of proteolysisGO:00301622930.192
Human
oogenesisGO:004847720.189
Fly
osteoblast differentiationGO:0001649920.189
Mouse
apoptotic signaling pathwayGO:00971902680.189
Human
positive regulation of locomotionGO:00400171860.188
embryonic organ developmentGO:0048568360.188
smooth muscle cell differentiationGO:005114580.187
regulation of cell growthGO:00015581350.186
Human
negative regulation of protein metabolic processGO:00512483910.185
Human
neuron projection developmentGO:00311751060.185
Rat
negative regulation of defense responseGO:0031348470.185
neural tube formationGO:000184130.184
organ inductionGO:000175940.183
hematopoietic or lymphoid organ developmentGO:00485341860.181
Zebrafish
pericardium developmentGO:006003920.180
septum secundum developmentGO:000328520.177
regulation of multivesicular body sizeGO:001079610.177
establishment of ribosome localizationGO:003375340.171
ear morphogenesisGO:004247170.171
protein autoubiquitinationGO:0051865370.171
peptidyl serine phosphorylationGO:00181051010.171
Human
regulation of cell migrationGO:00303342890.169
regulation of potassium ion transmembrane transportGO:1901379200.169
post embryonic developmentGO:000979120.168
Fly
morphogenesis of embryonic epitheliumGO:001633140.167
cofactor metabolic processGO:0051186870.166
regulation of heart morphogenesisGO:200082640.166
regulation of potassium ion transmembrane transporter activityGO:1901016160.165
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.164
histone acetylationGO:0016573930.159
regulation of mitotic cell cycle phase transitionGO:19019901180.157
Fly
regulation of bone mineralizationGO:0030500290.156
actin cytoskeleton organizationGO:00300362070.156
glial cell migrationGO:000834740.154
segmentationGO:003528240.152
Fly
positive regulation of protein serine threonine kinase activityGO:00719021190.152
i kappab kinase nf kappab signalingGO:00072491660.151
monocarboxylic acid biosynthetic processGO:0072330670.151
system processGO:00030083490.151
sensory organ morphogenesisGO:0090596210.151
Fly
g2 m transition of mitotic cell cycleGO:0000086410.150
ras protein signal transductionGO:0007265730.147
androgen receptor signaling pathwayGO:0030521340.147
regulation of cytoplasmic transportGO:19036491490.146
Human
memoryGO:000761330.145
positive regulation of cellular amino acid metabolic processGO:004576430.145
immune system developmentGO:00025201950.144
Zebrafish
heart loopingGO:000194770.143
cell divisionGO:00513011680.143
Fly
actin filament based processGO:00300292240.143
wnt signaling pathwayGO:00160551560.141
Human
single organism cell adhesionGO:00986021790.139
Human
cellular protein catabolic processGO:00442572610.139
Human
regulation of potassium ion transportGO:0043266240.138
positive regulation of cardiac muscle cell differentiationGO:200072740.136
isoprenoid metabolic processGO:0006720390.135
blood vessel endothelial cell migrationGO:0043534420.134
regulation of transmembrane transporter activityGO:0022898740.132
motor neuron axon guidanceGO:000804520.131
positive regulation of immune system processGO:00026842830.131
negative regulation of multi organism processGO:0043901920.130
protein stabilizationGO:0050821640.130
Human
muscle organ developmentGO:0007517560.130
drinking behaviorGO:004275610.127
sensory organ developmentGO:0007423520.127
Fly
potassium ion transmembrane transportGO:0071805600.126

SMAD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.820
Human
disease of cellular proliferationDOID:145661740.820
Human
bone diseaseDOID:0080001880.782
musculoskeletal system diseaseDOID:172230.782
connective tissue diseaseDOID:651090.782
organ system cancerDOID:00506861640.514
Human
gonadal diseaseDOID:227780.188
endocrine system diseaseDOID:28260.188
reproductive system diseaseDOID:15170.188