Homo sapiens

34 known processes

DHFR

dihydrofolate reductase

(Aliases: DHFRP1,DYR)

DHFR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811980.230
dna recombinationGO:0006310770.120
protein maturationGO:00516042330.093
post embryonic developmentGO:000979120.087
cellular response to dna damage stimulusGO:00069743790.083
protein processingGO:00164852260.069
mitotic cell cycleGO:00002783260.061
regulation of dna metabolic processGO:00510521530.059
ribonucleotide catabolic processGO:00092614050.059
double strand break repairGO:00063021010.054
nucleotide biosynthetic processGO:00091651090.049
regulation of proteolysisGO:00301622930.047
positive regulation of hydrolase activityGO:00513453310.045
nucleoside phosphate biosynthetic processGO:19012931090.043
oxidation reduction processGO:00551143960.040
meiotic chromosome segregationGO:004513240.039
cellular macromolecular complex assemblyGO:00346223240.039
regulation of cell cycle processGO:00105642660.039
immune system developmentGO:00025201950.033
chromatin organizationGO:00063253510.031
response to abiotic stimulusGO:00096283360.031
cellular amino acid metabolic processGO:00065201160.030
response to external biotic stimulusGO:00432072610.030
regenerationGO:003109940.030
negative regulation of organelle organizationGO:00106391260.029
female gamete generationGO:000729220.029
biological adhesionGO:00226103310.029
dna packagingGO:0006323770.028
single organism reproductive processGO:0044702980.028
response to oxygen containing compoundGO:19017003690.027
cellular macromolecule catabolic processGO:00442653800.027
mitotic cell cycle processGO:19030472860.026
dna replicationGO:00062601160.025
response to lipidGO:00339932060.025
purine nucleoside triphosphate metabolic processGO:00091444120.024
regulation of protein processingGO:00706131500.024
regulation of cellular amino acid metabolic processGO:000652160.023
nuclear divisionGO:00002801280.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
regulation of cell divisionGO:00513021160.023
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.023
cellular ketone metabolic processGO:0042180800.023
protein oligomerizationGO:00512591730.022
regulation of endopeptidase activityGO:00525481700.022
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.022
ribonucleoside monophosphate catabolic processGO:00091581580.021
deoxyribonucleotide metabolic processGO:000926260.021
negative regulation of catalytic activityGO:00430863350.021
nucleoside triphosphate catabolic processGO:00091433940.021
negative regulation of protein modification processGO:00314002000.021
response to biotic stimulusGO:00096072760.021
mitotic cell cycle phase transitionGO:00447721620.020
nucleic acid phosphodiester bond hydrolysisGO:00903051020.020
cell cycle phase transitionGO:00447701730.020
cell adhesionGO:00071553250.020
nucleoside phosphate catabolic processGO:19012924120.020
regulation of meiotic cell cycleGO:005144540.020
negative regulation of cellular component organizationGO:00511292350.020
nucleoside catabolic processGO:00091644080.019
sex differentiationGO:0007548450.019
regulation of cell cycleGO:00517263930.019
cellular protein complex assemblyGO:00436231880.019
nucleoside triphosphate metabolic processGO:00091414220.019
immune responseGO:00069553070.019
secretionGO:00469032540.019
organelle fissionGO:00482851490.019
response to other organismGO:00517072610.019
negative regulation of cell deathGO:00605483450.019
response to radiationGO:00093141510.018
organophosphate biosynthetic processGO:00904071630.018
regulation of cellular ketone metabolic processGO:0010565500.018
positive regulation of programmed cell deathGO:00430682490.018
organonitrogen compound biosynthetic processGO:19015662000.018
positive regulation of cysteine type endopeptidase activityGO:2001056790.018
positive regulation of proteolysisGO:00458621420.018
purine nucleoside monophosphate metabolic processGO:00091261860.018
regulation of cysteine type endopeptidase activityGO:20001161270.017
regulation of protein ubiquitinationGO:0031396950.017
zymogen activationGO:0031638700.017
regulation of mitotic cell cycleGO:00073461890.017
regulation of nuclear divisionGO:0051783650.017
embryo developmentGO:00097901230.017
dna catabolic processGO:0006308490.017
positive regulation of immune system processGO:00026842830.017
regulation of peptidase activityGO:00525471800.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
purine ribonucleoside metabolic processGO:00461284370.017
determination of adult lifespanGO:000834020.016
negative regulation of programmed cell deathGO:00430693210.016
cellular response to oxygen containing compoundGO:19017012760.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of cell cycleGO:00457861930.016
reproductive processGO:00224141060.016
positive regulation of cell deathGO:00109422630.016
protein modification by small protein conjugationGO:00324463420.016
covalent chromatin modificationGO:00165692540.016
glycosyl compound catabolic processGO:19016584130.016
cell divisionGO:00513011680.016
hindbrain developmentGO:003090230.016
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.015
dna conformation changeGO:00711031130.015
regulation of cellular response to stressGO:00801352440.015
positive regulation of peptidase activityGO:0010952880.015
reproductive structure developmentGO:0048608550.015
nucleoside monophosphate metabolic processGO:00091231910.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
regulation of meiosisGO:004002030.014
posttranscriptional regulation of gene expressionGO:00106082130.014
response to activityGO:001482300.014
positive regulation of cell cycle processGO:00900681060.014
purine containing compound catabolic processGO:00725234110.014
cell cycle checkpointGO:00000751170.014
response to drugGO:0042493810.014
somatic recombination of immunoglobulin gene segmentsGO:001644740.013
regulation of nucleotide metabolic processGO:00061402690.013
negative regulation of apoptotic processGO:00430663160.013
regulation of response to dna damage stimulusGO:2001020940.013
multicellular organismal agingGO:001025930.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
negative regulation of cellular protein metabolic processGO:00322693530.012
purine nucleoside catabolic processGO:00061523980.012
dna catabolic process endonucleolyticGO:0000737370.012
mitotic nuclear divisionGO:00070671190.012
neuron fate commitmentGO:004866320.012
nervous system developmentGO:00073992930.012
purine ribonucleoside catabolic processGO:00461303980.012
proteasomal protein catabolic processGO:00104981760.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
negative regulation of mitotic cell cycleGO:00459301020.012
cellular amine metabolic processGO:0044106410.012
regulation of immune responseGO:00507762010.012
carbohydrate derivative biosynthetic processGO:19011372070.012
protein ubiquitinationGO:00165673140.011
oocyte differentiationGO:000999420.011
regulation of immune effector processGO:0002697910.011
positive regulation of immune responseGO:00507781590.011
positive regulation of endopeptidase activityGO:0010950840.011
response to inorganic substanceGO:00100351270.011
histone modificationGO:00165702510.011
membrane organizationGO:00610242920.011
positive regulation of transportGO:00510503360.011
amine metabolic processGO:0009308440.011
negative regulation of dna metabolic processGO:0051053570.011
response to oxidative stressGO:00069791210.011
dna biosynthetic processGO:0071897400.011
regulation of transferase activityGO:00513383550.011
nucleus localizationGO:005164710.010
chromatin modificationGO:00165682980.010
regulation of protein catabolic processGO:00421761550.010
establishment of nucleus localizationGO:004002310.010
protein dna complex assemblyGO:0065004640.010
regulation of dna repairGO:0006282470.010
production of molecular mediator of immune responseGO:0002440370.010
ribonucleoside triphosphate metabolic processGO:00091994120.010
regulation of lymphocyte activationGO:00512491030.010
negative regulation of catabolic processGO:00098951040.010
nucleotide catabolic processGO:00091664080.010
single organism cellular localizationGO:19025803320.010
purine nucleotide catabolic processGO:00061954050.010

DHFR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.028
cancerDOID:1621670.028
disease of cellular proliferationDOID:145661740.028
immune system diseaseDOID:29141550.024
inherited metabolic disorderDOID:6552420.022
disease of metabolismDOID:00146672950.022
hematopoietic system diseaseDOID:741000.006
anemiaDOID:2355550.004
macrocytic anemiaDOID:236130.001
megaloblastic anemiaDOID:1338230.001