Homo sapiens

80 known processes

HIST2H4A

histone cluster 2, H4a

(Aliases: HIST1H4C,HIST1H4B,HIST1H4A,HIST1H4H,HIST1H4F,HIST1H4E,HIST1H4D,HIST1H4K,HIST1H4J,HIST1H4I,H4/n,H4FN,H4,HIST1H4L,H4F2,HIST4H4,HIST2H4,FO108,HIST2H4B)

HIST2H4A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna replication dependent nucleosome assemblyGO:0006335320.795
nucleosome assemblyGO:0006334500.786
negative regulation of megakaryocyte differentiationGO:0045653160.631
chromatin assembly or disassemblyGO:0006333780.600
dna replication dependent nucleosome organizationGO:0034723320.508
chromatin assemblyGO:0031497610.499
dna replication independent nucleosome organizationGO:0034724270.485
dna replication independent nucleosome assemblyGO:0006336270.474
chromatin organizationGO:00063253510.287
dna conformation changeGO:00711031130.268
protein dna complex assemblyGO:0065004640.265
negative regulation of myeloid cell differentiationGO:0045638420.199
cellular macromolecular complex assemblyGO:00346223240.165
dna packagingGO:0006323770.164
megakaryocyte differentiationGO:0030219250.156
myeloid cell differentiationGO:00300991170.150
regulation of myeloid cell differentiationGO:0045637810.150
nucleosome organizationGO:0034728660.136
protein dna complex subunit organizationGO:0071824800.132
chromatin modificationGO:00165682980.131
histone modificationGO:00165702510.129
regulation of hematopoietic progenitor cell differentiationGO:1901532240.118
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.109
negative regulation of multicellular organismal processGO:00512413170.101
negative regulation of immune system processGO:00026831360.091
covalent chromatin modificationGO:00165692540.086
negative regulation of developmental processGO:00510932470.082
cellular response to dna damage stimulusGO:00069743790.075
negative regulation of hematopoietic progenitor cell differentiationGO:1901533180.074
immune system developmentGO:00025201950.072
post embryonic developmentGO:000979120.072
hemopoiesisGO:00300971800.063
regulation of cellular amine metabolic processGO:0033238110.062
dna repairGO:00062811980.062
regulation of cell differentiationGO:00455953930.062
cellular component disassemblyGO:0022411920.061
regulation of cellular ketone metabolic processGO:0010565500.059
hematopoietic or lymphoid organ developmentGO:00485341860.057
female gamete generationGO:000729220.057
negative regulation of cell differentiationGO:00455961710.057
cellular amino acid metabolic processGO:00065201160.055
protein complex disassemblyGO:0043241520.053
amine metabolic processGO:0009308440.053
cellular macromolecule catabolic processGO:00442653800.052
response to abiotic stimulusGO:00096283360.052
positive regulation of cellular component organizationGO:00511303760.050
protein alkylationGO:0008213740.048
cellular amine metabolic processGO:0044106410.048
cellular ketone metabolic processGO:0042180800.047
positive regulation of cellular amino acid metabolic processGO:004576430.047
regulation of cellular amino acid metabolic processGO:000652160.047
proteolysis involved in cellular protein catabolic processGO:00516032440.046
oogenesisGO:004847720.046
negative regulation of cellular protein metabolic processGO:00322693530.044
cell cycle checkpointGO:00000751170.044
negative regulation of protein metabolic processGO:00512483910.044
methylationGO:00322591060.042
determination of adult lifespanGO:000834020.041
modification dependent protein catabolic processGO:00199412090.040
purine ribonucleoside metabolic processGO:00461284370.038
purine nucleoside triphosphate metabolic processGO:00091444120.037
multicellular organismal agingGO:001025930.037
protein ubiquitinationGO:00165673140.037
positive regulation of cellular amine metabolic processGO:003324070.036
macromolecule methylationGO:0043414970.036
regulation of gene silencingGO:0060968240.036
purine nucleotide catabolic processGO:00061954050.036
macromolecular complex disassemblyGO:0032984600.036
nucleoside triphosphate metabolic processGO:00091414220.035
cellular response to uvGO:0034644320.035
hematopoietic progenitor cell differentiationGO:0002244380.034
regulation of cellular component biogenesisGO:00440872810.033
gene silencingGO:0016458490.033
ribonucleoside triphosphate metabolic processGO:00091994120.033
regulation of gene expression epigeneticGO:0040029730.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
immune responseGO:00069553070.032
segmentationGO:003528240.032
glycosyl compound catabolic processGO:19016584130.032
anatomical structure formation involved in morphogenesisGO:00486462840.031
rna processingGO:00063962550.031
ubiquitin dependent protein catabolic processGO:00065112060.031
cellular protein catabolic processGO:00442572610.030
ribonucleoside triphosphate catabolic processGO:00092033910.030
regulation of megakaryocyte differentiationGO:0045652220.030
protein catabolic processGO:00301633250.030
mrna metabolic processGO:00160711750.030
protein processingGO:00164852260.029
ribonucleoside catabolic processGO:00424544060.029
modification dependent macromolecule catabolic processGO:00436322120.029
nucleotide catabolic processGO:00091664080.028
proteasomal protein catabolic processGO:00104981760.028
purine nucleoside catabolic processGO:00061523980.028
neuromuscular junction developmentGO:000752830.028
regulation of mitotic cell cycleGO:00073461890.028
growthGO:00400072020.028
positive regulation of organelle organizationGO:00106381950.027
nucleoside phosphate catabolic processGO:19012924120.027
regulation of cell cycleGO:00517263930.027
protein modification by small protein conjugationGO:00324463420.027
cellular response to abiotic stimulusGO:00712141170.027
regulation of proteolysisGO:00301622930.026
regenerationGO:003109940.026
purine ribonucleoside catabolic processGO:00461303980.026
ribonucleotide catabolic processGO:00092614050.026
nucleoside triphosphate catabolic processGO:00091433940.026
nucleoside catabolic processGO:00091644080.026
organophosphate catabolic processGO:00464344300.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
protein localization to organelleGO:00333652800.024
ras protein signal transductionGO:0007265730.024
cell developmentGO:00484683280.024
protein methylationGO:0006479740.024
positive regulation of hydrolase activityGO:00513453310.024
innate immune responseGO:00450871780.024
mitotic cell cycle processGO:19030472860.023
locomotory behaviorGO:000762610.023
small gtpase mediated signal transductionGO:0007264780.023
protein maturationGO:00516042330.023
response to radiationGO:00093141510.023
cell projection organizationGO:00300302520.023
cellular response to radiationGO:0071478650.023
purine containing compound catabolic processGO:00725234110.023
posttranscriptional regulation of gene expressionGO:00106082130.023
response to uvGO:0009411730.023
negative regulation of programmed cell deathGO:00430693210.022
cytoplasmic transportGO:00164823790.022
defense responseGO:00069523150.021
mrna processingGO:00063971330.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
negative regulation of proteolysisGO:00458611320.021
adult locomotory behaviorGO:000834410.021
positive regulation of catabolic processGO:00098963100.021
cell morphogenesisGO:00009022960.021
enzyme linked receptor protein signaling pathwayGO:00071673030.020
oocyte differentiationGO:000999420.020
negative regulation of cell deathGO:00605483450.020
cell growthGO:00160491600.020
regulation of nucleotide metabolic processGO:00061402690.020
oxidation reduction processGO:00551143960.020
cellular protein complex assemblyGO:00436231880.020
positive regulation of cell proliferationGO:00082843010.020
negative regulation of catalytic activityGO:00430863350.020
cellular component morphogenesisGO:00329893140.019
response to light stimulusGO:0009416870.019
negative regulation of cell cycleGO:00457861930.019
maintenance of locationGO:00512351120.019
regulation of cell cycle processGO:00105642660.019
regulation of chromosome organizationGO:00330441030.019
response to oxygen containing compoundGO:19017003690.019
cellular lipid metabolic processGO:00442553030.019
regulation of cellular response to stressGO:00801352440.019
organelle fissionGO:00482851490.019
cell cycle phase transitionGO:00447701730.018
purine ribonucleotide catabolic processGO:00091544040.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
actin filament based processGO:00300292240.018
negative regulation of phosphate metabolic processGO:00459362670.018
negative regulation of cell proliferationGO:00082852280.018
histone methylationGO:0016571600.018
chromosome segregationGO:00070591140.018
oocyte developmentGO:004859910.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
spermatid differentiationGO:004851540.017
negative regulation of protein maturationGO:19033181420.017
lipid metabolic processGO:00066293810.017
response to cytokineGO:00340972320.017
positive regulation of phosphorylationGO:00423273940.017
rho protein signal transductionGO:0007266260.017
regulation of protein processingGO:00706131500.016
neurogenesisGO:00220081690.016
carbohydrate derivative biosynthetic processGO:19011372070.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
carbohydrate metabolic processGO:00059752070.016
chemical homeostasisGO:00488783060.016
response to growth factorGO:00708482050.016
dna damage checkpointGO:0000077680.016
apoptotic signaling pathwayGO:00971902680.016
nervous system developmentGO:00073992930.016
chromatin silencingGO:0006342120.016
dephosphorylationGO:00163112090.016
single organism cellular localizationGO:19025803320.016
negative regulation of cellular component organizationGO:00511292350.016
regulation of purine nucleotide metabolic processGO:19005422640.016
regulation of chromatin organizationGO:1902275560.016
negative regulation of hydrolase activityGO:00513461820.016
gtp catabolic processGO:00061842370.016
regulation of endopeptidase activityGO:00525481700.015
positive regulation of transportGO:00510503360.015
positive regulation of cellular catabolic processGO:00313312840.015
response to external biotic stimulusGO:00432072610.015
cell projection morphogenesisGO:00488581290.015
regulation of dna metabolic processGO:00510521530.015
mitotic cell cycle phase transitionGO:00447721620.015
generation of neuronsGO:00486991520.015
nitrogen compound transportGO:00717051910.015
signal transduction by phosphorylationGO:00230142970.015
regulation of growthGO:00400081650.015
response to hormoneGO:00097251750.015
positive regulation of cell deathGO:00109422630.015
cell divisionGO:00513011680.015
vesicle mediated transportGO:00161923710.015
single organism reproductive processGO:0044702980.015
negative regulation of apoptotic processGO:00430663160.015
regulation of establishment of protein localizationGO:00702012420.015
cellular homeostasisGO:00197251960.015
single organism carbohydrate metabolic processGO:00447231930.015
wnt signaling pathwayGO:00160551560.014
regulation of purine nucleotide catabolic processGO:00331212050.014
organonitrogen compound biosynthetic processGO:19015662000.014
peptidyl tyrosine phosphorylationGO:00181081700.014
negative regulation of organelle organizationGO:00106391260.014
cellular chemical homeostasisGO:00550821800.014
negative regulation of protein modification processGO:00314002000.014
dna integrity checkpointGO:0031570710.014
single organism membrane organizationGO:00448022680.014
cellular response to growth factor stimulusGO:00713631970.014
cellular response to cytokine stimulusGO:00713451810.014
negative regulation of phosphorus metabolic processGO:00105632670.014
regulation of protein maturationGO:19033171500.014
positive regulation of developmental processGO:00510943140.014
ion homeostasisGO:00508012300.014
protein acylationGO:00435431380.014
positive regulation of apoptotic processGO:00430652460.014
organ morphogenesisGO:00098871470.014
regulation of cell motilityGO:20001452990.014
regulation of cellular component movementGO:00512703340.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
metal ion transportGO:00300012720.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of protein localizationGO:00328802960.014
regulation of protein kinase activityGO:00458592890.014
biological adhesionGO:00226103310.014
regulation of anatomical structure morphogenesisGO:00226032860.014
ion transmembrane transportGO:00342203380.013
neuron differentiationGO:00301821380.013
cellular response to endogenous stimulusGO:00714953360.013
blastoderm segmentationGO:000735020.013
regulation of peptidase activityGO:00525471800.013
hindbrain developmentGO:003090230.013
mitotic cell cycleGO:00002783260.013
regulation of protein transportGO:00512232130.013
positive regulation of protein phosphorylationGO:00019343130.013
regulation of kinase activityGO:00435493140.013
anterior posterior axis specificationGO:000994820.013
regulation of transferase activityGO:00513383550.013
regulation of cellular protein catabolic processGO:1903362960.013
regulation of cell divisionGO:00513021160.013
protein acetylationGO:00064731160.013
guanosine containing compound metabolic processGO:19010682440.013
peptidyl lysine acetylationGO:00183941010.013
regulation of response to external stimulusGO:00321012220.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
peptidyl lysine modificationGO:00182051440.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
positive regulation of programmed cell deathGO:00430682490.013
regulation of nucleotide catabolic processGO:00308112050.013
cellular response to oxygen containing compoundGO:19017012760.013
regulation of defense responseGO:00313471540.013
regulation of vesicle mediated transportGO:00606271300.013
compound eye developmentGO:004874910.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
cation transportGO:00068123310.013
response to biotic stimulusGO:00096072760.013
cation homeostasisGO:00550801890.013
gtp metabolic processGO:00460392390.013
regulation of cytoskeleton organizationGO:00514931770.013
regulation of protein catabolic processGO:00421761550.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
multi organism cellular processGO:00447641560.012
circulatory system developmentGO:00723592620.012
response to nitrogen compoundGO:19016981840.012
positive regulation of nucleoside metabolic processGO:00459791860.012
negative regulation of cell cycle processGO:00109481210.012
morphogenesis of embryonic epitheliumGO:001633140.012
viral processGO:00160321460.012
neuron developmentGO:00486661130.012
spermatid developmentGO:000728640.012
regulation of ras protein signal transductionGO:00465781550.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
positive regulation of nucleotide catabolic processGO:00308131850.012
system processGO:00030083490.012
regulation of locomotionGO:00400123290.012
organelle assemblyGO:00709251760.012
negative regulation of phosphorylationGO:00423261740.012
transmembrane transportGO:00550853990.012
regulation of multi organism processGO:00439001570.012
protein targetingGO:00066051870.012
protein oligomerizationGO:00512591730.012
atp metabolic processGO:00460341760.012
secretion by cellGO:00329402260.012
positive regulation of chromosome organizationGO:2001252410.012
positive regulation of cellular component biogenesisGO:00440891580.012
nuclear transportGO:00511691790.012
cell adhesionGO:00071553250.012
interspecies interaction between organismsGO:00444191560.012
mitotic nuclear divisionGO:00070671190.012
tripartite regional subdivisionGO:000735120.012
negative regulation of multi organism processGO:0043901920.012
peripheral nervous system developmentGO:000742220.012
negative regulation of cellular amine metabolic processGO:003323930.011
response to organic cyclic compoundGO:00140702040.011
cell part morphogenesisGO:00329901370.011
negative regulation of gene expression epigeneticGO:0045814190.011
sensory perceptionGO:00076001030.011
regulation of cell migrationGO:00303342890.011
ameboidal type cell migrationGO:00016671350.011
nerve developmentGO:002167540.011
viral life cycleGO:00190581320.011
atp catabolic processGO:00062001570.011
tissue regenerationGO:004224630.011
regulation of nucleoside metabolic processGO:00091182090.011
microtubule based processGO:00070172100.011
cell morphogenesis involved in differentiationGO:00009041440.011
actin cytoskeleton organizationGO:00300362070.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
nucleoside monophosphate catabolic processGO:00091251590.011
lipid biosynthetic processGO:00086101770.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
negative regulation of protein processingGO:00109551420.011
response to inorganic substanceGO:00100351270.011
regulation of cytoplasmic transportGO:19036491490.011
reactive oxygen species metabolic processGO:0072593750.011
guanosine containing compound catabolic processGO:19010692390.011
histone lysine methylationGO:0034968500.011
blood vessel developmentGO:00015681720.011
inorganic ion transmembrane transportGO:00986602310.011
ossificationGO:00015031210.011
divalent inorganic cation transportGO:00725111580.011
positive regulation of nucleotide metabolic processGO:00459812300.011
thymus developmentGO:004853830.011
cardiovascular system developmentGO:00723582620.011
intracellular protein transportGO:00068862700.011
positive regulation of cell cycleGO:00457871400.011
embryo developmentGO:00097901230.011
regulation of chromatin modificationGO:1903308510.011
cellular ion homeostasisGO:00068731680.011
taxisGO:00423301570.010
negative regulation of transferase activityGO:00513481240.010
negative regulation of intracellular signal transductionGO:19025321830.010
regulation of gtpase activityGO:00430871800.010
membrane organizationGO:00610242920.010
chemotaxisGO:00069351570.010
memoryGO:000761330.010
cellular response to light stimulusGO:0071482340.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
response to woundingGO:00096111680.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
response to lipidGO:00339932060.010
organ formationGO:004864530.010
positive regulation of kinase activityGO:00336742040.010
regulation of protein complex assemblyGO:00432541470.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
cell activationGO:00017752130.010
positive regulation of immune system processGO:00026842830.010
meiotic chromosome segregationGO:004513240.010
nuclear divisionGO:00002801280.010
regulation of cysteine type endopeptidase activityGO:20001161270.010

HIST2H4A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.022
sensory system diseaseDOID:00501552030.018
nervous system diseaseDOID:8634310.018
eye and adnexa diseaseDOID:14921500.017
central nervous system diseaseDOID:3311860.016
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
inherited metabolic disorderDOID:6552420.014
eye diseaseDOID:56141490.011
neurodegenerative diseaseDOID:12891020.010