Homo sapiens

0 known processes

LPIN1

lipin 1

(Aliases: KIAA0188,DKFZp781P1796,PAP1)

LPIN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.076
lipid metabolic processGO:00066293810.064
Mouse
cellular amino acid metabolic processGO:00065201160.063
determination of adult lifespanGO:000834020.059
cellular ketone metabolic processGO:0042180800.055
regulation of cellular ketone metabolic processGO:0010565500.051
purine ribonucleoside metabolic processGO:00461284370.051
multicellular organismal agingGO:001025930.049
regulation of cellular amino acid metabolic processGO:000652160.048
nucleoside triphosphate metabolic processGO:00091414220.048
organophosphate catabolic processGO:00464344300.048
cellular amine metabolic processGO:0044106410.048
amine metabolic processGO:0009308440.047
cellular lipid metabolic processGO:00442553030.046
Mouse
regulation of cellular amine metabolic processGO:0033238110.044
small gtpase mediated signal transductionGO:0007264780.044
purine containing compound catabolic processGO:00725234110.044
nucleoside phosphate catabolic processGO:19012924120.044
response to oxygen containing compoundGO:19017003690.043
Mouse
purine nucleoside triphosphate metabolic processGO:00091444120.043
nucleoside catabolic processGO:00091644080.043
glycosyl compound catabolic processGO:19016584130.042
ribonucleoside triphosphate metabolic processGO:00091994120.042
ribonucleoside catabolic processGO:00424544060.042
ribonucleotide catabolic processGO:00092614050.042
female gamete generationGO:000729220.042
cytoplasmic transportGO:00164823790.041
purine nucleotide catabolic processGO:00061954050.041
nucleotide catabolic processGO:00091664080.041
ribonucleoside triphosphate catabolic processGO:00092033910.041
locomotory behaviorGO:000762610.039
monocarboxylic acid metabolic processGO:00327871850.039
Mouse
ras protein signal transductionGO:0007265730.039
purine nucleoside catabolic processGO:00061523980.039
purine nucleoside triphosphate catabolic processGO:00091463920.039
positive regulation of catabolic processGO:00098963100.038
system processGO:00030083490.038
nucleoside triphosphate catabolic processGO:00091433940.038
oogenesisGO:004847720.038
purine ribonucleoside triphosphate catabolic processGO:00092073910.038
purine ribonucleotide catabolic processGO:00091544040.037
purine ribonucleoside catabolic processGO:00461303980.037
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
cellular macromolecule catabolic processGO:00442653800.035
regulation of cell differentiationGO:00455953930.035
Mouse
single organism cellular localizationGO:19025803320.035
negative regulation of cellular protein metabolic processGO:00322693530.035
oxidation reduction processGO:00551143960.035
negative regulation of protein metabolic processGO:00512483910.035
regulation of transferase activityGO:00513383550.034
lipid biosynthetic processGO:00086101770.034
regulation of cell cycleGO:00517263930.034
negative regulation of catalytic activityGO:00430863350.033
cellular response to endogenous stimulusGO:00714953360.033
Mouse
protein catabolic processGO:00301633250.033
positive regulation of cellular amino acid metabolic processGO:004576430.032
vesicle mediated transportGO:00161923710.032
small molecule biosynthetic processGO:00442831570.032
response to abiotic stimulusGO:00096283360.032
positive regulation of cellular component organizationGO:00511303760.032
Mouse
immune responseGO:00069553070.032
positive regulation of phosphorylationGO:00423273940.032
guanosine containing compound metabolic processGO:19010682440.032
rho protein signal transductionGO:0007266260.031
transmembrane transportGO:00550853990.031
cellular response to oxygen containing compoundGO:19017012760.031
Mouse
cation transportGO:00068123310.031
gtp metabolic processGO:00460392390.031
ion transmembrane transportGO:00342203380.030
positive regulation of transportGO:00510503360.030
biological adhesionGO:00226103310.030
segmentationGO:003528240.030
regulation of protein kinase activityGO:00458592890.030
fatty acid metabolic processGO:00066311150.029
Mouse
protein modification by small protein conjugationGO:00324463420.029
negative regulation of phosphate metabolic processGO:00459362670.029
positive regulation of cellular amine metabolic processGO:003324070.029
regulation of purine nucleotide metabolic processGO:19005422640.029
cellular component morphogenesisGO:00329893140.029
chemical homeostasisGO:00488783060.028
actin filament based processGO:00300292240.028
Mouse
apoptotic signaling pathwayGO:00971902680.028
positive regulation of cellular catabolic processGO:00313312840.028
cell morphogenesisGO:00009022960.028
negative regulation of phosphorus metabolic processGO:00105632670.028
cell developmentGO:00484683280.028
metal ion transportGO:00300012720.027
cell adhesionGO:00071553250.027
nervous system developmentGO:00073992930.027
cell projection organizationGO:00300302520.027
Mouse
neuromuscular junction developmentGO:000752830.027
cellular response to dna damage stimulusGO:00069743790.027
regulation of cell cycle processGO:00105642660.027
mitotic cell cycleGO:00002783260.027
regulation of kinase activityGO:00435493140.027
single organism membrane organizationGO:00448022680.027
positive regulation of hydrolase activityGO:00513453310.026
membrane organizationGO:00610242920.026
carbohydrate metabolic processGO:00059752070.026
regulation of protein localizationGO:00328802960.026
cellular macromolecular complex assemblyGO:00346223240.025
cellular protein catabolic processGO:00442572610.025
growthGO:00400072020.025
protein localization to organelleGO:00333652800.025
hindbrain developmentGO:003090230.025
single organism carbohydrate metabolic processGO:00447231930.025
gtp catabolic processGO:00061842370.024
defense responseGO:00069523150.024
regulation of nucleotide metabolic processGO:00061402690.024
negative regulation of cell deathGO:00605483450.024
regulation of cell motilityGO:20001452990.024
regulation of cell migrationGO:00303342890.024
protein ubiquitinationGO:00165673140.024
regenerationGO:003109940.024
regulation of proteolysisGO:00301622930.024
guanosine containing compound catabolic processGO:19010692390.024
regulation of locomotionGO:00400123290.024
maintenance of locationGO:00512351120.024
mitotic cell cycle processGO:19030472860.024
cation transmembrane transportGO:00986552380.024
regulation of cellular component biogenesisGO:00440872810.023
positive regulation of developmental processGO:00510943140.023
chromatin organizationGO:00063253510.023
Mouse
negative regulation of cellular component organizationGO:00511292350.023
regulation of cellular component movementGO:00512703340.023
memoryGO:000761330.023
regulation of nucleotide catabolic processGO:00308112050.023
organonitrogen compound biosynthetic processGO:19015662000.023
regulation of cellular response to stressGO:00801352440.022
positive regulation of protein phosphorylationGO:00019343130.022
positive regulation of cell deathGO:00109422630.022
rhythmic behaviorGO:000762220.022
positive regulation of nucleotide metabolic processGO:00459812300.022
protein maturationGO:00516042330.022
intracellular protein transportGO:00068862700.022
response to external biotic stimulusGO:00432072610.022
negative regulation of programmed cell deathGO:00430693210.022
regulation of purine nucleotide catabolic processGO:00331212050.022
regulation of anatomical structure morphogenesisGO:00226032860.022
negative regulation of apoptotic processGO:00430663160.022
response to lipidGO:00339932060.022
endomembrane system organizationGO:00102561960.022
response to biotic stimulusGO:00096072760.022
negative regulation of cellular amine metabolic processGO:003323930.022
adult locomotory behaviorGO:000834410.022
regulation of nucleoside metabolic processGO:00091182090.021
regulation of response to external stimulusGO:00321012220.021
protein processingGO:00164852260.021
dephosphorylationGO:00163112090.021
Mouse
blastoderm segmentationGO:000735020.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
response to other organismGO:00517072610.021
innate immune responseGO:00450871780.021
regulation of gtp catabolic processGO:00331241800.021
morphogenesis of embryonic epitheliumGO:001633140.021
regulation of establishment of protein localizationGO:00702012420.021
negative regulation of multicellular organismal processGO:00512413170.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
ion homeostasisGO:00508012300.021
carboxylic acid biosynthetic processGO:0046394970.021
chromatin modificationGO:00165682980.021
Mouse
negative regulation of cell proliferationGO:00082852280.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
inner ear morphogenesisGO:004247240.020
glycerolipid metabolic processGO:00464861070.020
Mouse
secretion by cellGO:00329402260.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
response to hormoneGO:00097251750.020
Mouse
regulation of cell growthGO:00015581350.020
inorganic ion transmembrane transportGO:00986602310.020
carbohydrate derivative biosynthetic processGO:19011372070.020
oocyte developmentGO:004859910.020
signal transduction by phosphorylationGO:00230142970.020
positive regulation of nucleoside metabolic processGO:00459791860.020
anion transportGO:00068201610.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of immune system processGO:00026842830.020
response to organic cyclic compoundGO:00140702040.020
positive regulation of apoptotic processGO:00430652460.019
cellular protein complex assemblyGO:00436231880.019
organophosphate biosynthetic processGO:00904071630.019
anterior posterior axis specificationGO:000994820.019
cell growthGO:00160491600.019
negative regulation of phosphorylationGO:00423261740.019
actin cytoskeleton organizationGO:00300362070.019
Mouse
regulation of immune responseGO:00507762010.019
regulation of growthGO:00400081650.019
oocyte differentiationGO:000999420.019
histone modificationGO:00165702510.019
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.019
spermatid differentiationGO:004851540.019
reactive oxygen species biosynthetic processGO:190340940.019
regulation of protein transportGO:00512232130.019
positive regulation of nucleotide catabolic processGO:00308131850.019
inorganic cation transmembrane transportGO:00986621940.018
positive regulation of transferase activityGO:00513472270.018
cellular homeostasisGO:00197251960.018
protein localization to membraneGO:00726571600.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
posttranscriptional regulation of gene expressionGO:00106082130.018
neuroblast proliferationGO:000740540.018
negative regulation of developmental processGO:00510932470.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
regulation of mitotic cell cycleGO:00073461890.018
regulation of cytokine productionGO:00018172320.018
negative regulation of protein modification processGO:00314002000.018
microtubule based processGO:00070172100.018
modification dependent macromolecule catabolic processGO:00436322120.018
reactive oxygen species metabolic processGO:0072593750.018
negative regulation of hydrolase activityGO:00513461820.018
mapk cascadeGO:00001652880.018
organic acid biosynthetic processGO:0016053970.018
regulation of mapk cascadeGO:00434082620.018
cellular response to hormone stimulusGO:00328701250.018
Mouse
protein oligomerizationGO:00512591730.018
organic hydroxy compound metabolic processGO:19016151470.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
circulatory system developmentGO:00723592620.018
regulation of cell adhesionGO:00301551660.018
circadian behaviorGO:004851220.018
positive regulation of cell proliferationGO:00082843010.018
regulation of protein serine threonine kinase activityGO:00719001790.017
regulation of multi organism processGO:00439001570.017
neurotransmitter secretionGO:000726940.017
positive regulation of kinase activityGO:00336742040.017
associative learningGO:000830610.017
proteasomal protein catabolic processGO:00104981760.017
regulation of gtpase activityGO:00430871800.017
negative regulation of cell cycleGO:00457861930.017
spermatid developmentGO:000728640.017
modification dependent protein catabolic processGO:00199412090.017
alcohol metabolic processGO:00060661140.017
protein targetingGO:00066051870.017
cardiac muscle cell contractionGO:008600340.017
cytokine productionGO:00018162470.017
regulation of synaptic plasticityGO:004816730.017
positive regulation of organelle organizationGO:00106381950.017
Mouse
regulation of ras protein signal transductionGO:00465781550.017
reactive nitrogen species metabolic processGO:200105730.017
cell cycle phase transitionGO:00447701730.017
regulation of neural precursor cell proliferationGO:200017740.017
regulation of ion transportGO:00432691890.017
positive regulation of programmed cell deathGO:00430682490.017
positive regulation of protein kinase activityGO:00458601900.017
response to organonitrogen compoundGO:00102431560.017
Mouse
epithelium developmentGO:00604292270.017
regulation of reactive oxygen species biosynthetic processGO:190342630.016
cardiovascular system developmentGO:00723582620.016
limbic system developmentGO:002176130.016
covalent chromatin modificationGO:00165692540.016
Mouse
positive regulation of gtp catabolic processGO:00331261660.016
regulation of intracellular transportGO:00323861950.016
organ formationGO:004864530.016
regulation of apoptotic signaling pathwayGO:20012331750.016
embryonic epithelial tube formationGO:000183840.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
cell activationGO:00017752130.016
response to nitrogen compoundGO:19016981840.016
Mouse
positive regulation of cell differentiationGO:00455972110.016
wnt signaling pathwayGO:00160551560.016
secretionGO:00469032540.016
motor neuron axon guidanceGO:000804520.016
organelle assemblyGO:00709251760.016
matingGO:000761810.016
neurological system processGO:00508771630.016
organic anion transportGO:00157111030.016
anterior posterior axis specification embryoGO:000859520.016
mitotic cell cycle phase transitionGO:00447721620.016
peripheral nervous system developmentGO:000742220.016
response to growth factorGO:00708482050.015
establishment of protein localization to membraneGO:00901501210.015
actin mediated cell contractionGO:0070252120.015
lipid localizationGO:00108761060.015
ubiquitin dependent protein catabolic processGO:00065112060.015
photoreceptor cell differentiationGO:004653020.015
cell divisionGO:00513011680.015
cellular response to growth factor stimulusGO:00713631970.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
regulation of cytoskeleton organizationGO:00514931770.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
tripartite regional subdivisionGO:000735120.015
positive regulation of gtpase activityGO:00435471660.015
mitochondrion organizationGO:00070051560.015
Mouse
cellular chemical homeostasisGO:00550821800.015
nuclear transportGO:00511691790.015
negative regulation of protein phosphorylationGO:00019331400.015
regulation of cell developmentGO:00602841610.015
morphogenesis of a polarized epitheliumGO:000173830.015
positive regulation of synaptic transmissionGO:005080640.015
response to radiationGO:00093141510.015
atp metabolic processGO:00460341760.015
regulation of peptidase activityGO:00525471800.015
cellular response to cytokine stimulusGO:00713451810.015
response to cytokineGO:00340972320.015
regulation of protein catabolic processGO:00421761550.015
monocarboxylic acid biosynthetic processGO:0072330670.015
nucleoside monophosphate metabolic processGO:00091231910.015
cell part morphogenesisGO:00329901370.015
compound eye developmentGO:004874910.015
dna repairGO:00062811980.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
cerebellum developmentGO:002154920.015
monovalent inorganic cation transportGO:00156721280.015
establishment of protein localization to organelleGO:00725941720.015
cell fate determinationGO:000170930.015
nerve developmentGO:002167540.014
microtubule cytoskeleton organizationGO:00002261760.014
regulation of endopeptidase activityGO:00525481700.014
nucleocytoplasmic transportGO:00069131760.014
regulation of ras gtpase activityGO:00323181280.014
cell substrate adhesionGO:00315891320.014
rna processingGO:00063962550.014
spinal cord developmentGO:002151040.014
nitrogen compound transportGO:00717051910.014
neurogenesisGO:00220081690.014
generation of neuronsGO:00486991520.014
positive regulation of cellular component movementGO:00512721810.014
neural tube formationGO:000184130.014
response to axon injuryGO:004867810.014
negative regulation of transportGO:00510511760.014
single organism cell adhesionGO:00986021790.014
divalent metal ion transportGO:00708381520.014
regulation of cell morphogenesisGO:00226041530.014
regulation of wnt signaling pathwayGO:00301111230.014
metencephalon developmentGO:002203720.014
regulation of secretionGO:00510461940.014
epithelial cell differentiationGO:00308551410.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
hemopoiesisGO:00300971800.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
taxisGO:00423301570.014
rab protein signal transductionGO:003248240.014
cell projection assemblyGO:00300311260.014
rna interferenceGO:001624640.014
visual behaviorGO:000763220.014
divalent inorganic cation transportGO:00725111580.014
cellular cation homeostasisGO:00300031630.014
regulation of protein processingGO:00706131500.014
actin filament based movementGO:0030048170.014
lipid transportGO:0006869900.014
syncytium formation by plasma membrane fusionGO:000076820.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
positive regulation of cell migrationGO:00303351720.013
endosomal transportGO:00161971290.013
t cell differentiation in thymusGO:003307740.013
cell projection morphogenesisGO:00488581290.013
cation homeostasisGO:00550801890.013
regulation of meiotic cell cycleGO:005144540.013
cellular ion homeostasisGO:00068731680.013
regulation of neurotransmitter secretionGO:004692830.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
Mouse
regulation of protein maturationGO:19033171500.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
cell morphogenesis involved in differentiationGO:00009041440.013
negative regulation of protein processingGO:00109551420.013
calcium ion transportGO:00068161470.013
cellular response to organonitrogen compoundGO:00714171240.013
Mouse
interspecies interaction between organismsGO:00444191560.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
chemotaxisGO:00069351570.013
phospholipid metabolic processGO:0006644990.013
positive regulation of proteolysisGO:00458621420.013
response to woundingGO:00096111680.013
long chain fatty acid metabolic processGO:0001676300.013
regulation of secretion by cellGO:19035301770.013
regulation of cytoplasmic transportGO:19036491490.013
regulation of vesicle mediated transportGO:00606271300.013
negative regulation of proteolysisGO:00458611320.013
tube closureGO:006060630.013
cellular response to lipidGO:00713961270.013
myoblast fusionGO:000752010.013
negative regulation of growthGO:0045926970.013
cellular response to nitrogen compoundGO:19016991440.013
Mouse
stem cell divisionGO:001714520.013
immune effector processGO:00022521590.013
sequestering of calcium ionGO:0051208170.013
leukocyte activationGO:00453211640.013
sulfur compound metabolic processGO:00067901010.013
positive regulation of ras gtpase activityGO:00323201170.013
negative regulation of transferase activityGO:00513481240.013
endocytosisGO:00068971590.012
response to extracellular stimulusGO:0009991850.012
regulation of cell cycle phase transitionGO:19019871260.012
metal ion homeostasisGO:00550651690.012
response to fungusGO:000962040.012
negative regulation of cell differentiationGO:00455961710.012
protein modification by small protein removalGO:0070646920.012
organelle fissionGO:00482851490.012
Mouse
immune system developmentGO:00025201950.012
negative regulation of protein maturationGO:19033181420.012
negative regulation of cell cycle processGO:00109481210.012
establishment of tissue polarityGO:000716430.012
long term memoryGO:000761620.012
response to nutrient levelsGO:0031667810.012
negative regulation of organelle organizationGO:00106391260.012
atp catabolic processGO:00062001570.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
small molecule catabolic processGO:0044282920.012
Mouse
tissue regenerationGO:004224630.012
steroid metabolic processGO:0008202940.012
plasma membrane organizationGO:00070091150.012
neural tube closureGO:000184330.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
sequestering of metal ionGO:0051238240.012
establishment of planar polarityGO:000173630.012
cofactor metabolic processGO:0051186870.012
negative regulation of immune system processGO:00026831360.012
sensory perception of painGO:001923340.012
negative regulation of blood pressureGO:004577630.012
cellular metal ion homeostasisGO:00068751460.012
cellular carbohydrate metabolic processGO:0044262840.012
meiotic chromosome segregationGO:004513240.012
glycoprotein metabolic processGO:00091001100.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
neuron differentiationGO:00301821380.012
positive regulation of cellular component biogenesisGO:00440891580.012
meiosis iGO:000712740.012
primary neural tube formationGO:001402030.012
lung alveolus developmentGO:004828640.012
cellular response to organic cyclic compoundGO:00714071270.012
regulation of transmembrane transportGO:00347621390.012
multi organism cellular processGO:00447641560.012
regulation of defense responseGO:00313471540.012
peptidyl lysine modificationGO:00182051440.012
protein deubiquitinationGO:0016579790.012
nucleus localizationGO:005164710.012
single organismal cell cell adhesionGO:00163371480.012
regulation of dna metabolic processGO:00510521530.012
protein homooligomerizationGO:00512601000.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
carboxylic acid transportGO:0046942630.012
salivary gland morphogenesisGO:000743540.012
negative regulation of kinase activityGO:00336731060.012
central nervous system developmentGO:00074171230.012
sex determinationGO:000753030.011
response to oxygen levelsGO:00704821000.011
response to inorganic substanceGO:00100351270.011
regulation of metal ion transportGO:00109591200.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
epidermis morphogenesisGO:004873030.011
developmental programmed cell deathGO:001062330.011
positive regulation of cytokine productionGO:00018191670.011
thymus developmentGO:004853830.011
mrna metabolic processGO:00160711750.011
epithelial cell proliferationGO:00506731280.011
positive regulation of neural precursor cell proliferationGO:200017920.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
protein localization to nucleusGO:00345041360.011
post embryonic organ developmentGO:004856910.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
regulation of protein complex assemblyGO:00432541470.011
regulation of cell projection organizationGO:00313441070.011
protein localization to plasma membraneGO:0072659930.011
negative regulation of catabolic processGO:00098951040.011
regulation of membrane potentialGO:0042391950.011
regulation of cell activationGO:00508651250.011
positive regulation of mapk cascadeGO:00434101900.011
g protein coupled receptor signaling pathwayGO:00071862070.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
reproductive processGO:00224141060.011
startle responseGO:000196430.011
i kappab kinase nf kappab signalingGO:00072491660.011
peptidyl serine modificationGO:00182091060.011
neuron developmentGO:00486661130.011
response to virusGO:00096151260.011
canonical wnt signaling pathwayGO:00600701160.011
convergent extensionGO:006002610.011
blood vessel morphogenesisGO:00485141620.011
protein autophosphorylationGO:00467771230.011
positive regulation of gliogenesisGO:001401540.011
negative regulation of cell growthGO:0030308830.011

LPIN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.038
inherited metabolic disorderDOID:6552420.036
musculoskeletal system diseaseDOID:172230.029
sensory system diseaseDOID:00501552030.024
nervous system diseaseDOID:8634310.024
central nervous system diseaseDOID:3311860.022
disease of cellular proliferationDOID:145661740.021
organ system cancerDOID:00506861640.020
cancerDOID:1621670.020
muscular diseaseDOID:00800001140.019
muscle tissue diseaseDOID:661130.019
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
immune system diseaseDOID:29141550.018
myopathyDOID:4231040.018
cardiovascular system diseaseDOID:12871060.016
retinal diseaseDOID:56791180.015
connective tissue diseaseDOID:651090.014
neurodegenerative diseaseDOID:12891020.013
bone diseaseDOID:0080001880.013
retinal degenerationDOID:8466890.012
brain diseaseDOID:936730.012