Homo sapiens

10 known processes

APH1B

anterior pharynx defective 1 homolog B (C. elegans)

(Aliases: PRO1328,PSFL,DKFZp564D0372,TAAV688,FLJ33115,APH-1B)

APH1B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.071
post embryonic developmentGO:000979120.058
amine metabolic processGO:0009308440.057
cellular amine metabolic processGO:0044106410.052
transmembrane transportGO:00550853990.051
cation transportGO:00068123310.050
regulation of cellular amino acid metabolic processGO:000652160.047
system processGO:00030083490.046
regulation of cellular amine metabolic processGO:0033238110.046
metal ion transportGO:00300012720.044
cellular ketone metabolic processGO:0042180800.041
regulation of cellular ketone metabolic processGO:0010565500.039
cellular lipid metabolic processGO:00442553030.039
cation transmembrane transportGO:00986552380.039
determination of adult lifespanGO:000834020.038
multicellular organismal agingGO:001025930.037
positive regulation of immune system processGO:00026842830.036
lipid metabolic processGO:00066293810.034
segmentationGO:003528240.034
positive regulation of transportGO:00510503360.032
ion transmembrane transportGO:00342203380.031
memoryGO:000761330.031
negative regulation of cellular protein metabolic processGO:00322693530.031
positive regulation of cellular amino acid metabolic processGO:004576430.030
negative regulation of protein metabolic processGO:00512483910.030
negative regulation of multicellular organismal processGO:00512413170.030
negative regulation of catalytic activityGO:00430863350.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
purine ribonucleoside metabolic processGO:00461284370.029
immune responseGO:00069553070.029
purine containing compound catabolic processGO:00725234110.029
nucleoside triphosphate metabolic processGO:00091414220.029
positive regulation of cellular amine metabolic processGO:003324070.028
cytoplasmic transportGO:00164823790.028
intracellular protein transportGO:00068862700.028
protein maturationGO:00516042330.027
oogenesisGO:004847720.027
ribonucleoside catabolic processGO:00424544060.027
purine nucleoside catabolic processGO:00061523980.027
nucleotide catabolic processGO:00091664080.027
nucleoside phosphate catabolic processGO:19012924120.027
inorganic ion transmembrane transportGO:00986602310.027
ribonucleoside triphosphate catabolic processGO:00092033910.026
positive regulation of cellular component organizationGO:00511303760.026
organophosphate catabolic processGO:00464344300.026
negative regulation of cellular amine metabolic processGO:003323930.026
negative regulation of phosphorus metabolic processGO:00105632670.026
cellular macromolecule catabolic processGO:00442653800.025
glycosyl compound catabolic processGO:19016584130.025
nucleoside triphosphate catabolic processGO:00091433940.025
regulation of synaptic plasticityGO:004816730.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
inorganic cation transmembrane transportGO:00986621940.025
female gamete generationGO:000729220.025
defense responseGO:00069523150.025
chemical homeostasisGO:00488783060.025
response to external biotic stimulusGO:00432072610.025
neurological system processGO:00508771630.024
nucleoside catabolic processGO:00091644080.024
purine ribonucleoside catabolic processGO:00461303980.024
positive regulation of catabolic processGO:00098963100.024
carbohydrate metabolic processGO:00059752070.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
protein localization to organelleGO:00333652800.024
single organism cellular localizationGO:19025803320.024
purine nucleotide catabolic processGO:00061954050.024
regulation of protein localizationGO:00328802960.024
positive regulation of phosphorylationGO:00423273940.024
cell adhesionGO:00071553250.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
regulation of transferase activityGO:00513383550.023
positive regulation of cellular catabolic processGO:00313312840.023
biological adhesionGO:00226103310.023
small gtpase mediated signal transductionGO:0007264780.023
locomotory behaviorGO:000762610.023
ras protein signal transductionGO:0007265730.023
purine ribonucleotide catabolic processGO:00091544040.023
regulation of proteolysisGO:00301622930.023
nervous system developmentGO:00073992930.022
cell morphogenesisGO:00009022960.022
cardiac muscle cell contractionGO:008600340.022
positive regulation of hydrolase activityGO:00513453310.022
regulation of protein kinase activityGO:00458592890.022
response to abiotic stimulusGO:00096283360.022
regulation of immune responseGO:00507762010.022
cellular component morphogenesisGO:00329893140.022
cell projection organizationGO:00300302520.022
negative regulation of phosphate metabolic processGO:00459362670.022
ribonucleotide catabolic processGO:00092614050.022
regulation of kinase activityGO:00435493140.022
single organism carbohydrate metabolic processGO:00447231930.022
neuromuscular junction developmentGO:000752830.022
ion homeostasisGO:00508012300.022
protein ubiquitinationGO:00165673140.022
regenerationGO:003109940.022
regulation of cell differentiationGO:00455953930.022
protein catabolic processGO:00301633250.021
lung alveolus developmentGO:004828640.021
regulation of cellular component movementGO:00512703340.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
actin filament based processGO:00300292240.021
innate immune responseGO:00450871780.021
cytokine productionGO:00018162470.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
protein modification by small protein conjugationGO:00324463420.021
regulation of protein transportGO:00512232130.020
positive regulation of immune responseGO:00507781590.020
cation homeostasisGO:00550801890.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
cellular response to endogenous stimulusGO:00714953360.020
dephosphorylationGO:00163112090.020
cellular response to oxygen containing compoundGO:19017012760.020
regulation of cell cycleGO:00517263930.020
regulation of establishment of protein localizationGO:00702012420.020
single organism membrane organizationGO:00448022680.020
secretion by cellGO:00329402260.019
organophosphate biosynthetic processGO:00904071630.019
negative regulation of protein maturationGO:19033181420.019
cell activationGO:00017752130.019
immune response regulating signaling pathwayGO:0002764970.019
vesicle mediated transportGO:00161923710.019
response to other organismGO:00517072610.019
cellular macromolecular complex assemblyGO:00346223240.019
regulation of locomotionGO:00400123290.019
negative regulation of apoptotic processGO:00430663160.019
response to biotic stimulusGO:00096072760.019
lipid biosynthetic processGO:00086101770.019
negative regulation of cellular component organizationGO:00511292350.019
guanosine containing compound catabolic processGO:19010692390.018
protein targetingGO:00066051870.018
striated muscle contractionGO:0006941520.018
ubiquitin dependent protein catabolic processGO:00065112060.018
cardiac muscle contractionGO:0060048340.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
regulation of cell motilityGO:20001452990.018
blastoderm segmentationGO:000735020.018
carbohydrate derivative biosynthetic processGO:19011372070.018
cellular homeostasisGO:00197251960.018
regulation of cellular component biogenesisGO:00440872810.018
negative regulation of cell deathGO:00605483450.018
gtp metabolic processGO:00460392390.018
guanosine containing compound metabolic processGO:19010682440.018
negative regulation of protein modification processGO:00314002000.018
immune effector processGO:00022521590.018
cellular protein catabolic processGO:00442572610.018
regulation of anatomical structure morphogenesisGO:00226032860.018
muscle system processGO:0003012810.017
positive regulation of protein phosphorylationGO:00019343130.017
cellular response to dna damage stimulusGO:00069743790.017
anion transportGO:00068201610.017
hemopoiesisGO:00300971800.017
mitotic cell cycleGO:00002783260.017
nitrogen compound transportGO:00717051910.017
positive regulation of developmental processGO:00510943140.017
positive regulation of cell deathGO:00109422630.017
rho protein signal transductionGO:0007266260.017
muscle contractionGO:0006936730.017
protein processingGO:00164852260.017
oxidation reduction processGO:00551143960.017
proteasomal protein catabolic processGO:00104981760.017
adult locomotory behaviorGO:000834410.017
regulation of purine nucleotide metabolic processGO:19005422640.017
regulation of cellular response to stressGO:00801352440.017
cellular cation homeostasisGO:00300031630.017
positive regulation of kinase activityGO:00336742040.017
metal ion homeostasisGO:00550651690.017
associative learningGO:000830610.017
thymus developmentGO:004853830.017
oocyte differentiationGO:000999420.017
regulation of intracellular transportGO:00323861950.017
positive regulation of transferase activityGO:00513472270.017
protein localization to membraneGO:00726571600.016
maintenance of locationGO:00512351120.016
modification dependent macromolecule catabolic processGO:00436322120.016
somitogenesisGO:000175620.016
positive regulation of programmed cell deathGO:00430682490.016
divalent inorganic cation transportGO:00725111580.016
apoptotic signaling pathwayGO:00971902680.016
negative regulation of intracellular signal transductionGO:19025321830.016
microtubule based processGO:00070172100.016
cellular chemical homeostasisGO:00550821800.016
organonitrogen compound biosynthetic processGO:19015662000.016
negative regulation of developmental processGO:00510932470.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
reactive oxygen species biosynthetic processGO:190340940.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of protein processingGO:00109551420.016
reactive oxygen species metabolic processGO:0072593750.016
regulation of protein maturationGO:19033171500.016
regulation of nucleotide metabolic processGO:00061402690.016
negative regulation of programmed cell deathGO:00430693210.016
regulation of protein processingGO:00706131500.016
regulation of secretionGO:00510461940.016
positive regulation of cytokine productionGO:00018191670.016
negative regulation of phosphorylationGO:00423261740.015
negative regulation of proteolysisGO:00458611320.015
spermatid differentiationGO:004851540.015
anatomical structure homeostasisGO:00602491000.015
detection of stimulusGO:0051606850.015
regulation of protein catabolic processGO:00421761550.015
nucleoside monophosphate metabolic processGO:00091231910.015
mitotic cell cycle processGO:19030472860.015
immune system developmentGO:00025201950.015
gtp catabolic processGO:00061842370.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
divalent metal ion transportGO:00708381520.015
cell projection assemblyGO:00300311260.015
membrane organizationGO:00610242920.015
positive regulation of secretionGO:00510471160.015
posttranscriptional regulation of gene expressionGO:00106082130.015
regulation of cell cycle processGO:00105642660.015
rhythmic behaviorGO:000762220.015
calcium ion transportGO:00068161470.015
compound eye developmentGO:004874910.015
actin filament based movementGO:0030048170.015
brain morphogenesisGO:004885410.015
negative regulation of cell proliferationGO:00082852280.015
hindbrain developmentGO:003090230.015
mapk cascadeGO:00001652880.015
actin mediated cell contractionGO:0070252120.015
small molecule biosynthetic processGO:00442831570.015
positive regulation of cell proliferationGO:00082843010.015
circulatory system developmentGO:00723592620.015
regulation of ion transportGO:00432691890.015
cellular ion homeostasisGO:00068731680.015
oocyte developmentGO:004859910.015
anterior posterior axis specificationGO:000994820.015
cell growthGO:00160491600.015
endomembrane system organizationGO:00102561960.015
positive regulation of cell differentiationGO:00455972110.015
motor neuron axon guidanceGO:000804520.014
cellular amide metabolic processGO:0043603690.014
regulation of cytokine productionGO:00018172320.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
spermatid developmentGO:000728640.014
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.014
morphogenesis of embryonic epitheliumGO:001633140.014
leukocyte activationGO:00453211640.014
positive regulation of protein transportGO:00512221350.014
reactive nitrogen species metabolic processGO:200105730.014
cellular metal ion homeostasisGO:00068751460.014
regulation of hormone levelsGO:00108171250.014
response to oxygen containing compoundGO:19017003690.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
negative regulation of hydrolase activityGO:00513461820.014
positive regulation of nucleotide metabolic processGO:00459812300.014
neuroblast proliferationGO:000740540.014
cell developmentGO:00484683280.014
cellular protein complex assemblyGO:00436231880.014
establishment of protein localization to organelleGO:00725941720.014
negative regulation of protein phosphorylationGO:00019331400.014
carboxylic acid biosynthetic processGO:0046394970.014
growthGO:00400072020.014
positive regulation of cell motilityGO:20001471770.014
organic acid biosynthetic processGO:0016053970.014
detection of chemical stimulus involved in sensory perceptionGO:0050907330.014
histone modificationGO:00165702510.014
photoreceptor cell differentiationGO:004653020.014
modification dependent protein catabolic processGO:00199412090.013
lymphocyte activationGO:00466491330.013
t cell activationGO:0042110990.013
nicotinate transportGO:200114210.013
circadian behaviorGO:004851220.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
positive regulation of mapk cascadeGO:00434101900.013
carnitine transmembrane transportGO:190260330.013
negative regulation of cellular catabolic processGO:0031330830.013
positive regulation of intestinal epithelial structure maintenanceGO:006073110.013
calcium ion transmembrane transportGO:0070588760.013
regulation of purine nucleotide catabolic processGO:00331212050.013
peripheral nervous system developmentGO:000742220.013
sodium independent organic anion transportGO:004325220.013
secretionGO:00469032540.013
monocarboxylic acid metabolic processGO:00327871850.013
matingGO:000761810.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
regulation of response to external stimulusGO:00321012220.013
regulation of protein serine threonine kinase activityGO:00719001790.013
peptide metabolic processGO:0006518510.013
positive regulation of protein kinase activityGO:00458601900.013
positive regulation of gtp catabolic processGO:00331261660.013
embryonic epithelial tube formationGO:000183840.013
regulation of nucleotide catabolic processGO:00308112050.013
regulation of mapk cascadeGO:00434082620.013
positive regulation of secretion by cellGO:19035321080.013
chromatin organizationGO:00063253510.013
regulation of secretion by cellGO:19035301770.013
glycerolipid metabolic processGO:00464861070.013
positive regulation of synaptic transmissionGO:005080640.013
glycoprotein metabolic processGO:00091001100.013
positive regulation of nucleoside metabolic processGO:00459791860.013
activation of immune responseGO:00022531140.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
positive regulation of nucleotide catabolic processGO:00308131850.013
sequestering of metal ionGO:0051238240.013
defense response to other organismGO:00985421290.013
sulfur compound metabolic processGO:00067901010.013
response to cytokineGO:00340972320.013
regulation of neural precursor cell proliferationGO:200017740.013
neurotransmitter secretionGO:000726940.013
response to bacteriumGO:00096171440.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
tripartite regional subdivisionGO:000735120.013
nucleocytoplasmic transportGO:00069131760.013
negative regulation of immune system processGO:00026831360.012
response to axon injuryGO:004867810.012
regulation of endopeptidase activityGO:00525481700.012
limbic system developmentGO:002176130.012
nerve developmentGO:002167540.012
cell part morphogenesisGO:00329901370.012
regulation of defense responseGO:00313471540.012
anterior posterior axis specification embryoGO:000859520.012
response to fungusGO:000962040.012
visual behaviorGO:000763220.012
regulation of cell growthGO:00015581350.012
positive regulation of cellular component movementGO:00512721810.012
nuclear transportGO:00511691790.012
sensory perception of painGO:001923340.012
phospholipid metabolic processGO:0006644990.012
regulation of intracellular protein transportGO:00331571230.012
negative regulation of catabolic processGO:00098951040.012
inner ear morphogenesisGO:004247240.012
syncytium formation by plasma membrane fusionGO:000076820.012
epithelial cell differentiationGO:00308551410.012
cofactor metabolic processGO:0051186870.012
cardiovascular system developmentGO:00723582620.012
negative regulation of transferase activityGO:00513481240.012
metencephalon developmentGO:002203720.012
positive regulation of gtpase activityGO:00435471660.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
stem cell divisionGO:001714520.012
atp metabolic processGO:00460341760.012
organic hydroxy compound metabolic processGO:19016151470.012
regulation of cytoskeleton organizationGO:00514931770.012
short chain fatty acid importGO:001591310.012
neurogenesisGO:00220081690.012
multi organism cellular processGO:00447641560.012
cell divisionGO:00513011680.012
regulation of growthGO:00400081650.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
chromatin modificationGO:00165682980.012
tissue regenerationGO:004224630.012
negative regulation of kinase activityGO:00336731060.012
signal transduction by phosphorylationGO:00230142970.012
peptidyl tyrosine modificationGO:00182121700.012
peptidyl tyrosine phosphorylationGO:00181081700.012
circulatory system processGO:00030131130.012
positive regulation of regulatory t cell differentiationGO:004559130.012
protein oligomerizationGO:00512591730.012
regulation of multi organism processGO:00439001570.012
response to growth factorGO:00708482050.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
regulation of gtp catabolic processGO:00331241800.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of meiotic cell cycleGO:005144540.012
positive regulation of organelle organizationGO:00106381950.012
sequestering of calcium ionGO:0051208170.012
rna interferenceGO:001624640.012
homeostasis of number of cells in a free living populationGO:004887410.012
regulation of peptidase activityGO:00525471800.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
sex determinationGO:000753030.012
divalent inorganic cation homeostasisGO:00725071360.012
regulation of cell migrationGO:00303342890.012
cell cycle phase transitionGO:00447701730.012
regulation of nucleoside metabolic processGO:00091182090.012
alpha ketoglutarate transportGO:001574210.012
i kappab kinase nf kappab signalingGO:00072491660.012
negative regulation of cell cycleGO:00457861930.012
dna repairGO:00062811980.012
neural tube patterningGO:002153220.012
symbiosis encompassing mutualism through parasitismGO:00444031560.011
generation of neuronsGO:00486991520.011
negative regulation of transportGO:00510511760.011
monovalent inorganic cation transportGO:00156721280.011
regulation of protein complex assemblyGO:00432541470.011
organ formationGO:004864530.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
regulation of gtpase activityGO:00430871800.011
negative regulation of organelle organizationGO:00106391260.011
positive regulation of defense responseGO:0031349870.011
regulation of innate immune responseGO:0045088970.011
organic anion transportGO:00157111030.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
rna processingGO:00063962550.011
sensory perceptionGO:00076001030.011
tissue homeostasisGO:0001894630.011
urate transportGO:001574730.011
organelle assemblyGO:00709251760.011
central nervous system developmentGO:00074171230.011
cilium organizationGO:0044782680.011
cerebellum developmentGO:002154920.011
regulation of cytoplasmic transportGO:19036491490.011
response to virusGO:00096151260.011
salivary gland morphogenesisGO:000743540.011
protein importGO:00170381300.011
positive regulation of proteolysisGO:00458621420.011
single organism cell adhesionGO:00986021790.011
microtubule cytoskeleton organizationGO:00002261760.011
covalent chromatin modificationGO:00165692540.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
regulation of ras protein signal transductionGO:00465781550.011
regulation of apoptotic signaling pathwayGO:20012331750.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
regulation of bindingGO:00510981110.011
endosomal transportGO:00161971290.011
blood circulationGO:00080151130.011
mitotic cell cycle phase transitionGO:00447721620.011
negative regulation of protein kinase activityGO:0006469980.011
angiogenesisGO:00015251470.011
glycerophospholipid metabolic processGO:0006650840.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
anion transmembrane transportGO:0098656760.011
regulation of membrane potentialGO:0042391950.011
regulation of cell projection organizationGO:00313441070.011
positive regulation of locomotionGO:00400171860.011
cell substrate adhesionGO:00315891320.011
long term memoryGO:000761620.011
detection of chemical stimulusGO:0009593550.011
interspecies interaction between organismsGO:00444191560.011
regulation of lymphocyte activationGO:00512491030.011
regulation of vesicle mediated transportGO:00606271300.011
actin cytoskeleton organizationGO:00300362070.011
meiosis iGO:000712740.010
negative regulation of blood pressureGO:004577630.010
positive regulation of intracellular transportGO:00323881040.010
regulation of cell morphogenesisGO:00226041530.010
regulation of mitotic cell cycleGO:00073461890.010
wnt signaling pathwayGO:00160551560.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of regulatory t cell differentiationGO:004558940.010
carboxylic acid transportGO:0046942630.010
response to lipidGO:00339932060.010
sensory perception of smellGO:000760820.010
cilium assemblyGO:0042384630.010
cellular response to cytokine stimulusGO:00713451810.010
fatty acid metabolic processGO:00066311150.010
multicellular organismal homeostasisGO:0048871670.010
plasma membrane organizationGO:00070091150.010
regulation of ras gtpase activityGO:00323181280.010
regulation of dna metabolic processGO:00510521530.010
cellular calcium ion homeostasisGO:00068741170.010
neuron developmentGO:00486661130.010
quorum sensing involved in interaction with hostGO:005210610.010
neuron differentiationGO:00301821380.010
response to hormoneGO:00097251750.010
tube closureGO:006060630.010
behavioral response to ethanolGO:004814920.010
blood vessel morphogenesisGO:00485141620.010
response to nitrogen compoundGO:19016981840.010
cell fate determinationGO:000170930.010
head developmentGO:00603221080.010
neural tube formationGO:000184130.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.010
cellular response to organonitrogen compoundGO:00714171240.010
myoblast fusionGO:000752010.010
sleepGO:003043120.010
mitochondrion organizationGO:00070051560.010
immune response activating signal transductionGO:0002757900.010
positive regulation of ras gtpase activityGO:00323201170.010

APH1B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.061
inherited metabolic disorderDOID:6552420.041
nervous system diseaseDOID:8634310.036
central nervous system diseaseDOID:3311860.036
musculoskeletal system diseaseDOID:172230.033
cardiovascular system diseaseDOID:12871060.026
sensory system diseaseDOID:00501552030.024
eye diseaseDOID:56141490.020
eye and adnexa diseaseDOID:14921500.020
muscular diseaseDOID:00800001140.019
muscle tissue diseaseDOID:661130.019
myopathyDOID:4231040.019
neurodegenerative diseaseDOID:12891020.019
cancerDOID:1621670.018
disease of cellular proliferationDOID:145661740.018
connective tissue diseaseDOID:651090.017
organ system cancerDOID:00506861640.017
bone diseaseDOID:0080001880.016
heart diseaseDOID:114680.015
retinal diseaseDOID:56791180.015
immune system diseaseDOID:29141550.014
intrinsic cardiomyopathyDOID:0060036500.014
cardiomyopathyDOID:0050700500.014
brain diseaseDOID:936730.012
dilated cardiomyopathyDOID:12930320.012
retinal degenerationDOID:8466890.012
disease of mental healthDOID:150700.011
neuropathyDOID:870520.011
hematopoietic system diseaseDOID:741000.010