Homo sapiens

189 known processes

SMAD2

SMAD family member 2

(Aliases: MGC22139,MADR2,MADH2,JV18,hMAD-2,hSMAD2,MGC34440,JV18-1)

SMAD2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781251.000
regulation of activin receptor signaling pathwayGO:0032925141.000
zygotic specification of dorsal ventral axisGO:000735221.000
transforming growth factor beta receptor signaling pathwayGO:0007179761.000
evasion or tolerance of host defenses by virusGO:001904921.000
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222811.000
Human Zebrafish
peptidyl threonine modificationGO:0018210451.000
Human
evasion or tolerance of host defensesGO:004441521.000
Human
regulation of cell differentiationGO:00455953931.000
Human Zebrafish Mouse
response to host defensesGO:005220021.000
Human
mapk cascadeGO:00001652881.000
protein modification by small protein conjugationGO:00324463421.000
Human
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190022411.000
modification dependent macromolecule catabolic processGO:00436322121.000
Human
regulation of wnt signaling pathwayGO:00301111231.000
Human
regulation of stress activated mapk cascadeGO:0032872841.000
positive regulation of bmp signaling pathwayGO:003051391.000
regulation of nodal signaling pathway involved in determination of left right asymmetryGO:190014511.000
regulation of mesoderm developmentGO:200038041.000
kidney developmentGO:0001822531.000
Mouse
anatomical structure formation involved in morphogenesisGO:00486462841.000
Mouse
cellular response to endogenous stimulusGO:00714953361.000
vasculature developmentGO:00019441810.999
response to transforming growth factor betaGO:0071559940.999
response to sterolGO:0036314140.999
regulation of mapk cascadeGO:00434082620.999
smad protein complex assemblyGO:0007183120.999
gastrulationGO:0007369510.999
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.999
Human
cardiovascular system developmentGO:00723582620.999
Mouse
common partner smad protein phosphorylationGO:000718230.999
response to hostGO:007513620.999
Human
negative regulation of pathway restricted smad protein phosphorylationGO:0060394110.999
Human
negative regulation of transcription by competitive promoter bindingGO:001094480.999
Human
positive regulation of protein import into nucleusGO:0042307460.999
Human
ubiquitin dependent protein catabolic processGO:00065112060.999
Human
mesonephros developmentGO:0001823170.999
Mouse
hematopoietic or lymphoid organ developmentGO:00485341860.999
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.999
negative regulation of peptidyl threonine phosphorylationGO:001080160.999
Human
activin receptor signaling pathwayGO:0032924240.998
regulation of nucleocytoplasmic transportGO:0046822980.998
Human
regulation of proteasomal protein catabolic processGO:0061136870.998
Human
regulation of cell adhesionGO:00301551660.998
Human
embryonic cranial skeleton morphogenesisGO:004870160.998
Mouse
regulation of protein import into nucleusGO:0042306780.998
Human
post embryonic developmentGO:000979120.998
Mouse
embryonic morphogenesisGO:0048598850.998
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.998
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190017510.998
circulatory system developmentGO:00723592620.997
Mouse
regulation of osteoblast differentiationGO:0045667380.997
response to oxygen containing compoundGO:19017003690.997
cellular response to transforming growth factor beta stimulusGO:0071560940.997
immune system developmentGO:00025201950.997
dorsal ventral pattern formationGO:0009953150.997
regulation of ossificationGO:0030278580.997
cytoplasmic transportGO:00164823790.996
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.996
endodermal cell fate commitmentGO:000171140.996
regulation of cell cycleGO:00517263930.996
Human Worm
myeloid cell differentiationGO:00300991170.996
mesonephric epithelium developmentGO:0072163140.996
Mouse
wnt signaling pathwayGO:00160551560.996
Human
cellular response to growth factor stimulusGO:00713631970.996
positive regulation of erythrocyte differentiationGO:0045648110.996
positive regulation of canonical wnt signaling pathwayGO:0090263330.996
Human
negative regulation of bmp signaling pathwayGO:0030514170.996
Human
regulation of protein localizationGO:00328802960.996
Human
regulation of nodal signaling pathwayGO:190010710.995
positive regulation of cytoplasmic transportGO:1903651820.995
Human
regulation of interleukin 1 beta productionGO:0032651180.995
chromatin modificationGO:00165682980.995
bmp signaling pathwayGO:0030509490.995
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100410.995
cell substrate adhesionGO:00315891320.995
Human
endoderm formationGO:0001706330.995
Mouse
regulation of biomineral tissue developmentGO:0070167310.994
single organism cell adhesionGO:00986021790.994
Human
negative regulation of apoptotic processGO:00430663160.994
Human
lateral mesoderm developmentGO:004836810.994
organ morphogenesisGO:00098871470.994
Mouse
cellular ketone metabolic processGO:0042180800.994
cell cell junction organizationGO:0045216690.993
Human
chemical homeostasisGO:00488783060.993
positive regulation of osteoblast differentiationGO:0045669230.993
protein catabolic processGO:00301633250.993
Human
avoidance of defenses of other organism involved in symbiotic interactionGO:005183220.992
Human
atp catabolic processGO:00062001570.992
nucleocytoplasmic transportGO:00069131760.992
Human
hemopoiesisGO:00300971800.992
myeloid cell homeostasisGO:0002262340.991
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512280.991
Human
signal transduction by phosphorylationGO:00230142970.991
somatic stem cell maintenanceGO:003501940.991
peptidyl serine phosphorylationGO:00181051010.990
Human
single organism cellular localizationGO:19025803320.990
Human
cell morphogenesis involved in differentiationGO:00009041440.990
Human Mouse
stress activated protein kinase signaling cascadeGO:0031098940.990
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.990
Human
tube morphogenesisGO:0035239950.990
Mouse
positive regulation of mesoderm developmentGO:200038220.990
negative regulation of developmental processGO:00510932470.990
small gtpase mediated signal transductionGO:0007264780.989
positive regulation of cell differentiationGO:00455972110.988
Human Zebrafish Mouse
peptidyl threonine phosphorylationGO:0018107410.988
Human
epithelial to mesenchymal transitionGO:0001837480.986
Human Mouse
nucleoside triphosphate metabolic processGO:00091414220.985
regulation of meiotic cell cycleGO:005144540.984
Worm
regulation of smad protein import into nucleusGO:0060390100.984
positive regulation of developmental processGO:00510943140.984
cell morphogenesisGO:00009022960.984
Human Mouse
response to organic cyclic compoundGO:00140702040.984
neuron projection developmentGO:00311751060.984
regulation of alkaline phosphatase activityGO:001069220.984
catenin import into nucleusGO:0035411180.984
Human
ureteric bud developmentGO:0001657130.983
Mouse
positive regulation of catabolic processGO:00098963100.983
Human
positive regulation of cell proliferationGO:00082843010.983
protein targeting to nucleusGO:00447441040.983
Human
regulation of growthGO:00400081650.982
Human Worm
muscle organ developmentGO:0007517560.982
regulation of cellular response to growth factor stimulusGO:0090287760.981
single organism nuclear importGO:19025931040.981
Human
negative regulation of multicellular organismal processGO:00512413170.981
positive regulation of wnt signaling pathwayGO:0030177540.980
Human
retinal ganglion cell axon guidanceGO:003129020.980
regulation of bone mineralizationGO:0030500290.980
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.980
Human
regulation of cell cell adhesionGO:0022407570.979
Human
negative regulation of phosphate metabolic processGO:00459362670.979
Human
regulation of cellular component biogenesisGO:00440872810.979
Human
mitotic cell cycle processGO:19030472860.979
osteoblast differentiationGO:0001649920.979
erythrocyte homeostasisGO:0034101310.979
negative regulation of phosphorylationGO:00423261740.978
Human
positive regulation of cellular component organizationGO:00511303760.978
Human Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510902110.978
Human
canonical wnt signaling pathwayGO:00600701160.978
Human
negative regulation of cell growthGO:0030308830.977
Human
positive regulation of mapk cascadeGO:00434101900.977
regulation of cellular protein catabolic processGO:1903362960.976
Human
negative regulation of cellular component organizationGO:00511292350.976
Human
regulation of jnk cascadeGO:0046328730.975
cell junction assemblyGO:0034329670.975
Human
regulation of bmp signaling pathwayGO:0030510270.975
cellular component morphogenesisGO:00329893140.975
Human Mouse
protein ubiquitinationGO:00165673140.974
Human
modulation by virus of host morphology or physiologyGO:0019048100.974
Human
mesonephric tubule developmentGO:0072164140.973
Mouse
somitogenesisGO:000175620.972
mesenchymal cell developmentGO:0014031500.972
Human Mouse
endodermal cell fate specificationGO:000171440.972
extrinsic apoptotic signaling pathwayGO:00971911190.972
Human
establishment of protein localization to organelleGO:00725941720.972
Human
protein importGO:00170381300.971
Human
tube developmentGO:00352951250.970
Mouse
nucleoside catabolic processGO:00091644080.970
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009410.969
regulation of epithelial to mesenchymal transitionGO:0010717370.967
Human Mouse
lens development in camera type eyeGO:000208820.967
nuclear transportGO:00511691790.967
Human
stem cell developmentGO:0048864690.966
Human Mouse
nucleoside triphosphate catabolic processGO:00091433940.966
segmentationGO:003528240.966
regulation of stress activated protein kinase signaling cascadeGO:0070302850.965
avoidance of host defensesGO:004441320.964
Human
neuron differentiationGO:00301821380.964
tissue morphogenesisGO:0048729960.963
Mouse
pattern specification processGO:0007389430.963
female gamete generationGO:000729220.963
Zebrafish
cell junction organizationGO:0034330790.963
Human
cell part morphogenesisGO:00329901370.963
oogenesisGO:004847720.962
Zebrafish
positive regulation of stem cell differentiationGO:2000738290.962
Human Mouse
nervous system developmentGO:00073992930.962
secretionGO:00469032540.961
Mouse
multicellular organismal agingGO:001025930.960
cytokine productionGO:00018162470.960
Human
response to other organismGO:00517072610.958
Human
muscle structure developmentGO:0061061980.958
stress activated mapk cascadeGO:0051403930.957
positive regulation of smad protein import into nucleusGO:006039180.956
cell fate commitmentGO:0045165270.956
Mouse
angiogenesisGO:00015251470.955
digestive system developmentGO:0055123750.955
Mouse
system processGO:00030083490.955
transforming growth factor beta productionGO:0071604140.955
Human
negative regulation of cell differentiationGO:00455961710.954
regulation of protein transportGO:00512232130.954
Human
erythrocyte differentiationGO:0030218280.954
negative regulation of smad protein complex assemblyGO:001099140.953
Human
stem cell divisionGO:001714520.951
regulation of transcription factor import into nucleusGO:0042990390.951
Human
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.950
Human
regulation of protein serine threonine kinase activityGO:00719001790.950
skin developmentGO:0043588760.950
chromatin organizationGO:00063253510.950
purine nucleoside triphosphate metabolic processGO:00091444120.949
morphogenesis of embryonic epitheliumGO:001633140.949
embryo developmentGO:00097901230.949
proteolysis involved in cellular protein catabolic processGO:00516032440.948
Human
modification of morphology or physiology of other organismGO:0035821430.947
Human
chemotaxisGO:00069351570.947
response to growth factorGO:00708482050.946
cellular protein catabolic processGO:00442572610.944
Human
negative regulation of cell proliferationGO:00082852280.944
Human Rat
modification dependent protein catabolic processGO:00199412090.943
Human
positive regulation of protein localization to nucleusGO:1900182480.942
Human
nuclear importGO:00511701060.942
Human
positive regulation of protein catabolic processGO:0045732750.940
Human
regulation of anatomical structure morphogenesisGO:00226032860.938
Human Mouse
mesenchymal cell differentiationGO:0048762520.937
Human Mouse
jnk cascadeGO:0007254800.935
protein import into nucleusGO:00066061040.934
Human
adherens junction organizationGO:0034332360.930
Human
ribonucleoside triphosphate catabolic processGO:00092033910.929
ameboidal type cell migrationGO:00016671350.929
gland developmentGO:0048732480.928
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.926
Human Mouse
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152220.925
regulation of cellular ketone metabolic processGO:0010565500.924
neurogenesisGO:00220081690.922
neural tube formationGO:000184130.920
proteasomal protein catabolic processGO:00104981760.920
Human
neuron fate commitmentGO:004866320.920
cellular response to oxygen containing compoundGO:19017012760.919
ossificationGO:00015031210.919
protein localization to organelleGO:00333652800.919
Human
positive regulation of cellular protein catabolic processGO:1903364370.918
Human
positive regulation of cellular catabolic processGO:00313312840.917
Human
neuroblast proliferationGO:000740540.917
positive regulation of ossificationGO:0045778320.915
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.915
Human
digestive tract developmentGO:0048565750.915
Mouse
pathway restricted smad protein phosphorylationGO:0060389380.915
Human
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.914
Human
cell cycle arrestGO:0007050710.914
Human
multi organism cellular processGO:00447641560.912
Human
regulation of ras protein signal transductionGO:00465781550.912
purine nucleotide catabolic processGO:00061954050.911
positive regulation of cell cell adhesionGO:0022409220.908
Human
nodal signaling pathwayGO:003809250.907
response to external biotic stimulusGO:00432072610.906
Human
blood vessel morphogenesisGO:00485141620.902
generation of neuronsGO:00486991520.901
positive regulation of activin receptor signaling pathwayGO:003292760.901
adherens junction assemblyGO:0034333340.900
Human
viral processGO:00160321460.898
Human
developmental growthGO:0048589480.896
Mouse Worm
positive regulation of cell adhesionGO:0045785840.894
Human
negative regulation of programmed cell deathGO:00430693210.894
Human
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.893
Human
mesodermal cell fate commitmentGO:000171020.891
bone mineralizationGO:0030282340.890
cell projection organizationGO:00300302520.886
single organismal cell cell adhesionGO:00163371480.885
Human
positive regulation of peptidase activityGO:0010952880.883
Human
positive regulation of epithelial to mesenchymal transitionGO:0010718220.881
Human Mouse
cell adhesionGO:00071553250.881
Human
taxisGO:00423301570.877
maintenance of protein locationGO:0045185570.875
regulation of protein kinase activityGO:00458592890.872
cellular amine metabolic processGO:0044106410.869
positive regulation of intracellular transportGO:00323881040.868
Human
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.866
Human
microtubule based processGO:00070172100.863
positive regulation of cell deathGO:00109422630.858
Human
positive regulation of protein phosphorylationGO:00019343130.858
regulation of cellular amine metabolic processGO:0033238110.858
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016410.858
cellular macromolecule catabolic processGO:00442653800.857
Human
interspecies interaction between organismsGO:00444191560.857
Human
positive regulation of programmed cell deathGO:00430682490.857
Human
positive regulation of stress activated mapk cascadeGO:0032874600.856
ribonucleoside catabolic processGO:00424544060.851
primary neural tube formationGO:001402030.851
endoderm developmentGO:0007492330.851
Mouse
cell fate determinationGO:000170930.850
amine metabolic processGO:0009308440.850
negative regulation of protein phosphorylationGO:00019331400.848
Human
organophosphate catabolic processGO:00464344300.848
positive regulation of catenin import into nucleusGO:003541390.847
Human
leukocyte differentiationGO:0002521980.844
urogenital system developmentGO:0001655650.844
Mouse
positive regulation of nucleocytoplasmic transportGO:0046824540.843
Human
blood vessel developmentGO:00015681720.840
regulation of establishment of protein localizationGO:00702012420.835
Human
heart developmentGO:0007507950.833
Mouse
regulation of proteolysisGO:00301622930.826
Human
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.823
Human
cell developmentGO:00484683280.822
Human Zebrafish Mouse
regulation of pathway restricted smad protein phosphorylationGO:0060393340.822
Human
interaction with hostGO:0051701420.821
Human
regulation of canonical wnt signaling pathwayGO:0060828880.819
Human
ribonucleotide catabolic processGO:00092614050.818
protein localization to nucleusGO:00345041360.818
Human
response to lipidGO:00339932060.818
intracellular protein transportGO:00068862700.816
Human
ribonucleoside triphosphate metabolic processGO:00091994120.809
regulation of cell growthGO:00015581350.804
Human
morphogenesis of an epitheliumGO:0002009600.803
response to biotic stimulusGO:00096072760.801
Human
mesoderm formationGO:0001707100.797
Mouse
immune responseGO:00069553070.796
Human
regulation of lipid metabolic processGO:0019216960.796
negative regulation of cell cycleGO:00457861930.795
Human Worm
regulation of actin filament based processGO:00329701410.793
digestive tract morphogenesisGO:0048546560.792
Mouse
positive regulation of proteasomal protein catabolic processGO:1901800350.788
Human
negative regulation of stress activated mapk cascadeGO:0032873190.787
positive regulation of meiotic cell cycleGO:005144620.783
Worm
positive regulation of intracellular protein transportGO:0090316760.780
Human
anterior posterior axis specificationGO:000994820.779
embryonic organ developmentGO:0048568360.778
Mouse
bleb assemblyGO:003206060.778
transdifferentiationGO:006029020.778
purine ribonucleoside catabolic processGO:00461303980.777
stem cell differentiationGO:0048863930.777
Human Mouse
evasion or tolerance of defenses of other organism involved in symbiotic interactionGO:005183420.777
Human
regulation of nervous system developmentGO:0051960880.776
positive regulation of cell cycleGO:00457871400.776
Worm
cell divisionGO:00513011680.772
protein autophosphorylationGO:00467771230.769
negative regulation of systemic arterial blood pressureGO:000308510.767
regulation of cartilage developmentGO:0061035120.767
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.763
regulation of peptidase activityGO:00525471800.760
Human
cell type specific apoptotic processGO:00972851250.759
cellular response to nutrient levelsGO:0031669690.756
regulation of protein modification by small protein conjugation or removalGO:19033201070.754
Human
regulation of intracellular transportGO:00323861950.752
Human
rho protein signal transductionGO:0007266260.752
regulation of protein targetingGO:1903533910.751
Human
positive regulation of developmental growthGO:0048639160.751
Worm
embryonic organ morphogenesisGO:0048562240.750
Mouse
response to cholesterolGO:0070723110.743
smad protein signal transductionGO:0060395100.742
Human Mouse
response to alcoholGO:0097305640.741
regulation of cytokine productionGO:00018172320.737
Human
signal releaseGO:0023061700.734
Mouse
cellular macromolecular complex assemblyGO:00346223240.732
cell cycle phase transitionGO:00447701730.728
ion homeostasisGO:00508012300.725
response to steroid hormoneGO:0048545800.719
cellular response to external stimulusGO:00714961110.719
neuron developmentGO:00486661130.719
regulation of cellular component movementGO:00512703340.718
axis specificationGO:0009798120.715
blastoderm segmentationGO:000735020.701
sensory organ developmentGO:0007423520.694
endocardial cushion developmentGO:000319730.692
positive regulation of homeostatic processGO:0032846470.688
endosome to lysosome transportGO:0008333210.687
regulation of cytoplasmic transportGO:19036491490.681
Human
regulation of peptidyl serine phosphorylationGO:0033135500.676
Human
blood circulationGO:00080151130.676
positive regulation of jnk cascadeGO:0046330520.671
regulation of protein ubiquitinationGO:0031396950.671
Human
negative regulation of protein metabolic processGO:00512483910.670
Human
regulation of kinase activityGO:00435493140.670
negative regulation of cell deathGO:00605483450.668
Human
regulation of neural precursor cell proliferationGO:200017740.663
regulation of cell morphogenesisGO:00226041530.661
Human Mouse
ras protein signal transductionGO:0007265730.659
embryonic heart tube morphogenesisGO:000314380.659
circulatory system processGO:00030131130.652
positive regulation of apoptotic processGO:00430652460.651
Human
cellular response to dna damage stimulusGO:00069743790.649
cell proliferation involved in heart valve developmentGO:200079310.648
sterol homeostasisGO:0055092280.646
memoryGO:000761330.646
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817380.645
Human
metal ion homeostasisGO:00550651690.644
positive regulation of protein transportGO:00512221350.644
Human
protein oligomerizationGO:00512591730.641
embryonic epithelial tube formationGO:000183840.638
positive regulation of myeloid cell differentiationGO:0045639390.638
determination of left right asymmetry in lateral mesodermGO:000314010.638
negative regulation of ubiquitin protein transferase activityGO:005144480.636
Human
oocyte developmentGO:004859910.632
Zebrafish
positive regulation of phosphorylationGO:00423273940.632
negative regulation of cellular amino acid metabolic processGO:004576320.631
regulation of locomotionGO:00400123290.628
metal ion transportGO:00300012720.626
regulation of cell projection organizationGO:00313441070.625
regulation of cell morphogenesis involved in differentiationGO:0010769830.625
Human Mouse
negative regulation of wnt signaling pathwayGO:0030178690.623
regulation of protein localization to nucleusGO:1900180850.622
Human
rna localizationGO:0006403410.620
negative regulation of cell cycle processGO:00109481210.616
organic hydroxy compound metabolic processGO:19016151470.616
protein targetingGO:00066051870.613
Human
regulation of cell cycle processGO:00105642660.613
kidney epithelium developmentGO:0072073250.612
Mouse
apoptotic signaling pathwayGO:00971902680.612
Human
regulation of transcription elongation from rna polymerase ii promoterGO:0034243130.610
steroid metabolic processGO:0008202940.607
positive regulation of endopeptidase activityGO:0010950840.605
Human
axon developmentGO:0061564340.596
positive regulation of biomineral tissue developmentGO:0070169200.594
regulation of transferase activityGO:00513383550.594
Human
cell projection morphogenesisGO:00488581290.594
positive regulation of proteolysisGO:00458621420.593
Human
positive regulation of map kinase activityGO:0043406800.589
determination of bilateral symmetryGO:0009855150.585
regulation of cell migrationGO:00303342890.585
cerebral cortex cell migrationGO:002179530.585
atp dependent chromatin remodelingGO:0043044250.584
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.584
positive regulation of kinase activityGO:00336742040.577
negative regulation of chondrocyte proliferationGO:190273110.574
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600390.572
positive regulation of cell motilityGO:20001471770.570
regulation of cell motilityGO:20001452990.564
cardiac muscle cell fate commitmentGO:006092340.561
peptidyl serine modificationGO:00182091060.560
Human
positive regulation of cellular component biogenesisGO:00440891580.557
blastocyst developmentGO:000182430.555
negative regulation of growthGO:0045926970.555
Human
endocrine system developmentGO:0035270260.551
regulation of cell substrate adhesionGO:0010810680.551
alcohol metabolic processGO:00060661140.549
regulation of cell substrate junction assemblyGO:0090109200.548
ribonucleoside monophosphate catabolic processGO:00091581580.547
positive regulation of transferase activityGO:00513472270.543
regulation of focal adhesion assemblyGO:0051893200.541
regulation of myeloid cell differentiationGO:0045637810.541
specification of symmetryGO:0009799160.541
purine ribonucleotide catabolic processGO:00091544040.540
cellular protein complex assemblyGO:00436231880.539
endodermal cell differentiationGO:0035987310.539
regulation of endopeptidase activityGO:00525481700.538
Human
negative regulation of peptidyl serine phosphorylationGO:003313780.537
Human
regulation of protein catabolic processGO:00421761550.534
Human
regionalizationGO:0003002290.533
purine ribonucleoside triphosphate catabolic processGO:00092073910.532
camera type eye developmentGO:0043010250.530
regulation of mitotic cell cycleGO:00073461890.529
Human Worm
axonogenesisGO:0007409310.527
cell cell signalingGO:00072671550.524
Mouse
cell substrate adherens junction assemblyGO:0007045300.523
positive regulation of organelle organizationGO:00106381950.521
regulation of endothelial cell differentiationGO:004560140.520
regulation of intracellular protein transportGO:00331571230.519
Human
lung developmentGO:0030324200.517
Mouse
regulation of smad protein complex assemblyGO:001099040.517
Human
regulation of secretion by cellGO:19035301770.513
androgen receptor signaling pathwayGO:0030521340.511
biological adhesionGO:00226103310.509
Human
positive regulation of cell developmentGO:0010720920.507
Human Zebrafish Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.506
Human
epithelium developmentGO:00604292270.506
Mouse
regulation of organ morphogenesisGO:2000027240.505
transcription factor import into nucleusGO:0042991400.502
Human
brain developmentGO:0007420970.501
regulation of dna templated transcription in response to stressGO:0043620180.497
cellular amino acid metabolic processGO:00065201160.491
positive regulation of dna templated transcription elongationGO:0032786180.490
regulation of mitotic cell cycle phase transitionGO:19019901180.484
epithelial cell differentiationGO:00308551410.481
behaviorGO:00076101120.481
regulation of immune responseGO:00507762010.480
focal adhesion assemblyGO:0048041300.476
protein maturationGO:00516042330.473
Human
lipid homeostasisGO:0055088390.471
regulation of cell junction assemblyGO:1901888290.467
positive regulation of ras gtpase activityGO:00323201170.467
oocyte differentiationGO:000999420.467
Zebrafish
nucleotide catabolic processGO:00091664080.466
neural tube closureGO:000184330.460
defense responseGO:00069523150.459
purine nucleoside monophosphate metabolic processGO:00091261860.458
dorsal ventral axis specificationGO:000995070.456
positive regulation of gtpase activityGO:00435471660.453
negative regulation of protein transportGO:0051224750.452
renal system developmentGO:0072001630.449
Mouse
cellular response to bmp stimulusGO:007177380.448
regulation of erk1 and erk2 cascadeGO:0070372990.448
response to laminar fluid shear stressGO:003461680.446
Human
regulation of chemotaxisGO:0050920740.438
response to estrogenGO:0043627470.427
negative regulation of phosphorus metabolic processGO:00105632670.427
Human
regulation of cell developmentGO:00602841610.426
Human Zebrafish Mouse
negative regulation of ion transportGO:0043271390.425
purine nucleoside triphosphate catabolic processGO:00091463920.418
positive regulation of rho gtpase activityGO:0032321560.417
protein processingGO:00164852260.409
Human
cardiac conductionGO:0061337230.409
hindlimb morphogenesisGO:003513720.408
regulation of cellular response to stressGO:00801352440.408
head developmentGO:00603221080.406

SMAD2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.897
Human
disease of cellular proliferationDOID:145661740.897
Human
organ system cancerDOID:00506861640.607
Human