Homo sapiens

149 known processes

SOST

sclerostin

(Aliases: VBCH)

SOST biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.080
regulation of cellular amine metabolic processGO:0033238110.071
cellular amine metabolic processGO:0044106410.070
amine metabolic processGO:0009308440.065
regulation of cellular amino acid metabolic processGO:000652160.065
post embryonic developmentGO:000979120.061
positive regulation of cellular amine metabolic processGO:003324070.056
positive regulation of cellular amino acid metabolic processGO:004576430.055
regulation of cellular ketone metabolic processGO:0010565500.051
cellular ketone metabolic processGO:0042180800.047
system processGO:00030083490.047
chemical homeostasisGO:00488783060.040
response to oxygen containing compoundGO:19017003690.040
negative regulation of cellular protein metabolic processGO:00322693530.039
regulation of transferase activityGO:00513383550.038
positive regulation of phosphorylationGO:00423273940.038
negative regulation of catalytic activityGO:00430863350.036
negative regulation of multicellular organismal processGO:00512413170.035
negative regulation of protein metabolic processGO:00512483910.034
negative regulation of apoptotic processGO:00430663160.034
multicellular organismal agingGO:001025930.034
negative regulation of cell deathGO:00605483450.034
cytoplasmic transportGO:00164823790.033
cardiovascular system developmentGO:00723582620.033
memoryGO:000761330.033
positive regulation of protein phosphorylationGO:00019343130.033
determination of adult lifespanGO:000834020.032
regulation of cell differentiationGO:00455953930.031
negative regulation of phosphorus metabolic processGO:00105632670.031
positive regulation of developmental processGO:00510943140.031
regulation of mapk cascadeGO:00434082620.031
locomotory behaviorGO:000762610.031
positive regulation of transportGO:00510503360.030
female gamete generationGO:000729220.030
nervous system developmentGO:00073992930.030
segmentationGO:003528240.030
negative regulation of phosphate metabolic processGO:00459362670.029
cellular homeostasisGO:00197251960.029
positive regulation of transferase activityGO:00513472270.029
positive regulation of cellular component organizationGO:00511303760.029
response to abiotic stimulusGO:00096283360.029
cation transportGO:00068123310.028
transmembrane transportGO:00550853990.028
cellular chemical homeostasisGO:00550821800.028
metal ion transportGO:00300012720.028
regulation of cell cycleGO:00517263930.028
regulation of kinase activityGO:00435493140.027
cellular macromolecule catabolic processGO:00442653800.027
response to organic cyclic compoundGO:00140702040.027
protein maturationGO:00516042330.027
regulation of protein kinase activityGO:00458592890.027
oogenesisGO:004847720.027
lipid metabolic processGO:00066293810.027
immune responseGO:00069553070.026
cellular cation homeostasisGO:00300031630.026
negative regulation of programmed cell deathGO:00430693210.026
regulation of anatomical structure morphogenesisGO:00226032860.026
organonitrogen compound biosynthetic processGO:19015662000.026
cell morphogenesisGO:00009022960.026
protein localization to organelleGO:00333652800.025
regulation of cell cycle processGO:00105642660.025
signal transduction by phosphorylationGO:00230142970.025
epithelium developmentGO:00604292270.025
regulation of cellular component movementGO:00512703340.025
ras protein signal transductionGO:0007265730.025
intracellular protein transportGO:00068862700.025
neuromuscular junction developmentGO:000752830.025
biological adhesionGO:00226103310.025
cellular response to dna damage stimulusGO:00069743790.025
positive regulation of cell differentiationGO:00455972110.025
enzyme linked receptor protein signaling pathwayGO:00071673030.025
morphogenesis of embryonic epitheliumGO:001633140.025
mapk cascadeGO:00001652880.025
positive regulation of hydrolase activityGO:00513453310.025
single organism cellular localizationGO:19025803320.024
purine containing compound catabolic processGO:00725234110.024
positive regulation of kinase activityGO:00336742040.024
protein processingGO:00164852260.024
purine ribonucleoside metabolic processGO:00461284370.024
cation homeostasisGO:00550801890.024
positive regulation of cell proliferationGO:00082843010.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
regulation of proteolysisGO:00301622930.023
cell adhesionGO:00071553250.023
ion homeostasisGO:00508012300.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
cytokine productionGO:00018162470.023
regulation of ion transportGO:00432691890.023
organophosphate catabolic processGO:00464344300.023
regulation of locomotionGO:00400123290.023
cellular component morphogenesisGO:00329893140.023
carbohydrate derivative biosynthetic processGO:19011372070.023
positive regulation of protein kinase activityGO:00458601900.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
divalent metal ion transportGO:00708381520.023
regenerationGO:003109940.023
mitotic cell cycleGO:00002783260.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
ribonucleotide catabolic processGO:00092614050.023
negative regulation of developmental processGO:00510932470.022
anatomical structure formation involved in morphogenesisGO:00486462840.022
nucleotide catabolic processGO:00091664080.022
nucleoside triphosphate metabolic processGO:00091414220.022
hindbrain developmentGO:003090230.022
circulatory system developmentGO:00723592620.022
single organism membrane organizationGO:00448022680.022
response to lipidGO:00339932060.022
membrane organizationGO:00610242920.022
cellular response to endogenous stimulusGO:00714953360.022
embryonic epithelial tube formationGO:000183840.022
ion transmembrane transportGO:00342203380.022
actin filament based processGO:00300292240.022
protein catabolic processGO:00301633250.022
metal ion homeostasisGO:00550651690.022
ribonucleoside triphosphate metabolic processGO:00091994120.022
neurological system processGO:00508771630.022
vesicle mediated transportGO:00161923710.021
regulation of nucleotide metabolic processGO:00061402690.021
cellular lipid metabolic processGO:00442553030.021
regulation of cytokine productionGO:00018172320.021
positive regulation of immune system processGO:00026842830.021
regulation of protein transportGO:00512232130.021
nucleoside phosphate catabolic processGO:19012924120.021
glycosyl compound catabolic processGO:19016584130.021
regulation of purine nucleotide metabolic processGO:19005422640.021
purine nucleoside catabolic processGO:00061523980.021
organic hydroxy compound metabolic processGO:19016151470.021
regulation of cell motilityGO:20001452990.021
regulation of establishment of protein localizationGO:00702012420.021
defense responseGO:00069523150.021
regulation of intracellular transportGO:00323861950.020
nucleoside triphosphate catabolic processGO:00091433940.020
small gtpase mediated signal transductionGO:0007264780.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
negative regulation of cell proliferationGO:00082852280.020
protein ubiquitinationGO:00165673140.020
positive regulation of apoptotic processGO:00430652460.020
ribonucleoside catabolic processGO:00424544060.020
cell developmentGO:00484683280.020
regulation of cell migrationGO:00303342890.020
positive regulation of programmed cell deathGO:00430682490.020
regulation of protein localizationGO:00328802960.020
negative regulation of cellular amine metabolic processGO:003323930.020
purine nucleotide catabolic processGO:00061954050.020
regulation of hormone levelsGO:00108171250.020
protein modification by small protein conjugationGO:00324463420.020
purine ribonucleotide catabolic processGO:00091544040.020
cell projection organizationGO:00300302520.019
response to external biotic stimulusGO:00432072610.019
wnt signaling pathwayGO:00160551560.019
negative regulation of hydrolase activityGO:00513461820.019
mitotic cell cycle processGO:19030472860.019
positive regulation of cell deathGO:00109422630.019
anterior posterior axis specificationGO:000994820.019
cell divisionGO:00513011680.019
cellular protein catabolic processGO:00442572610.019
blastoderm segmentationGO:000735020.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
cellular ion homeostasisGO:00068731680.019
positive regulation of cellular catabolic processGO:00313312840.019
peptidyl tyrosine phosphorylationGO:00181081700.019
calcium ion transportGO:00068161470.019
regulation of response to external stimulusGO:00321012220.018
nitrogen compound transportGO:00717051910.018
response to other organismGO:00517072610.018
negative regulation of cellular component organizationGO:00511292350.018
nucleoside catabolic processGO:00091644080.018
divalent inorganic cation homeostasisGO:00725071360.018
positive regulation of catabolic processGO:00098963100.018
negative regulation of phosphorylationGO:00423261740.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
blood vessel developmentGO:00015681720.018
calcium ion homeostasisGO:00550741220.018
organ morphogenesisGO:00098871470.018
response to nitrogen compoundGO:19016981840.018
cellular response to organic cyclic compoundGO:00714071270.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
vasculature developmentGO:00019441810.018
negative regulation of protein modification processGO:00314002000.018
response to hormoneGO:00097251750.018
organophosphate biosynthetic processGO:00904071630.018
cellular response to oxygen containing compoundGO:19017012760.018
cellular response to lipidGO:00713961270.018
single organism carbohydrate metabolic processGO:00447231930.017
negative regulation of transportGO:00510511760.017
dephosphorylationGO:00163112090.017
regulation of cellular response to stressGO:00801352440.017
innate immune responseGO:00450871780.017
oocyte developmentGO:004859910.017
limbic system developmentGO:002176130.017
cellular metal ion homeostasisGO:00068751460.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
positive regulation of organelle organizationGO:00106381950.017
carbohydrate metabolic processGO:00059752070.017
developmental programmed cell deathGO:001062330.017
oocyte differentiationGO:000999420.017
regulation of endopeptidase activityGO:00525481700.017
divalent inorganic cation transportGO:00725111580.017
protein targetingGO:00066051870.017
purine ribonucleoside catabolic processGO:00461303980.017
secretionGO:00469032540.017
forebrain generation of neuronsGO:002187230.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
inner ear morphogenesisGO:004247240.016
secretion by cellGO:00329402260.016
retina vasculature morphogenesis in camera type eyeGO:006129930.016
nerve developmentGO:002167540.016
cellular macromolecular complex assemblyGO:00346223240.016
peptidyl tyrosine modificationGO:00182121700.016
maintenance of locationGO:00512351120.016
rho protein signal transductionGO:0007266260.016
positive regulation of nucleotide metabolic processGO:00459812300.016
apoptotic signaling pathwayGO:00971902680.016
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.016
regulation of cellular component biogenesisGO:00440872810.016
negative regulation of cell differentiationGO:00455961710.016
photoreceptor cell differentiationGO:004653020.016
neuroblast proliferationGO:000740540.016
response to cytokineGO:00340972320.016
blood vessel morphogenesisGO:00485141620.016
spermatid differentiationGO:004851540.016
actin cytoskeleton organizationGO:00300362070.016
adult locomotory behaviorGO:000834410.016
canonical wnt signaling pathwayGO:00600701160.016
endomembrane system organizationGO:00102561960.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
response to radiationGO:00093141510.016
forelimb morphogenesisGO:003513640.016
organ formationGO:004864530.016
anterior posterior axis specification embryoGO:000859520.016
regulation of immune responseGO:00507762010.016
ossificationGO:00015031210.016
cellular response to growth factor stimulusGO:00713631970.016
positive regulation of cell cycleGO:00457871400.016
anion transportGO:00068201610.016
immune system developmentGO:00025201950.016
negative regulation of protein phosphorylationGO:00019331400.015
guanosine containing compound metabolic processGO:19010682440.015
peripheral nervous system developmentGO:000742220.015
regulation of cell developmentGO:00602841610.015
alcohol metabolic processGO:00060661140.015
regulation of peptidase activityGO:00525471800.015
regulation of cell divisionGO:00513021160.015
mammary gland morphogenesisGO:006044320.015
associative learningGO:000830610.015
response to biotic stimulusGO:00096072760.015
growthGO:00400072020.015
rhythmic behaviorGO:000762220.015
regulation of cytoplasmic transportGO:19036491490.015
response to organonitrogen compoundGO:00102431560.015
cell fate determinationGO:000170930.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
regulation of cell morphogenesisGO:00226041530.015
negative regulation of protein maturationGO:19033181420.015
regulation of mitotic cell cycleGO:00073461890.015
positive regulation of synaptic transmissionGO:005080640.015
angiogenesisGO:00015251470.015
lipid biosynthetic processGO:00086101770.015
nuclear transportGO:00511691790.015
metencephalon developmentGO:002203720.015
regulation of homeostatic processGO:00328441210.015
negative regulation of intracellular signal transductionGO:19025321830.015
oxidation reduction processGO:00551143960.015
long term memoryGO:000761620.015
central nervous system developmentGO:00074171230.014
regulation of transmembrane transportGO:00347621390.014
regulation of protein maturationGO:19033171500.014
motor neuron axon guidanceGO:000804520.014
response to growth factorGO:00708482050.014
tripartite regional subdivisionGO:000735120.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
regulation of secretionGO:00510461940.014
positive regulation of mesenchymal cell proliferationGO:000205320.014
blood circulationGO:00080151130.014
nucleocytoplasmic transportGO:00069131760.014
ameboidal type cell migrationGO:00016671350.014
regulation of protein serine threonine kinase activityGO:00719001790.014
sequestering of metal ionGO:0051238240.014
sequestering of calcium ionGO:0051208170.014
posttranscriptional regulation of gene expressionGO:00106082130.014
cranial nerve developmentGO:002154540.014
tissue regenerationGO:004224630.014
cardiac muscle cell contractionGO:008600340.014
circulatory system processGO:00030131130.014
regulation of protein processingGO:00706131500.014
regulation of secretion by cellGO:19035301770.014
gtp catabolic processGO:00061842370.014
spermatid developmentGO:000728640.014
compound eye developmentGO:004874910.014
stem cell differentiationGO:0048863930.014
purine nucleotide biosynthetic processGO:0006164840.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
small molecule biosynthetic processGO:00442831570.014
nucleotide biosynthetic processGO:00091651090.014
neurogenesisGO:00220081690.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
regulation of metal ion transportGO:00109591200.014
positive regulation of cellular component movementGO:00512721810.014
neural tube formationGO:000184130.014
cellular protein complex assemblyGO:00436231880.014
primary neural tube formationGO:001402030.014
epidermis morphogenesisGO:004873030.014
small molecule catabolic processGO:0044282920.013
somatic stem cell maintenanceGO:003501940.013
guanosine containing compound catabolic processGO:19010692390.013
gtp metabolic processGO:00460392390.013
circadian behaviorGO:004851220.013
regulation of purine nucleotide catabolic processGO:00331212050.013
negative regulation of transferase activityGO:00513481240.013
tube closureGO:006060630.013
positive regulation of nucleotide catabolic processGO:00308131850.013
cytosolic calcium ion homeostasisGO:0051480890.013
response to fungusGO:000962040.013
reactive oxygen species biosynthetic processGO:190340940.013
regulation of nucleoside metabolic processGO:00091182090.013
regulation of neural precursor cell proliferationGO:200017740.013
positive regulation of mapk cascadeGO:00434101900.013
toxin transportGO:190199840.013
positive regulation of intracellular transportGO:00323881040.013
regulation of intracellular protein transportGO:00331571230.013
histone modificationGO:00165702510.013
negative regulation of proteolysisGO:00458611320.013
negative regulation of protein processingGO:00109551420.013
cell growthGO:00160491600.013
somitogenesisGO:000175620.013
modification dependent protein catabolic processGO:00199412090.013
syncytium formation by plasma membrane fusionGO:000076820.013
specification of organ identityGO:001009230.013
embryonic forelimb morphogenesisGO:003511540.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
positive regulation of protein transportGO:00512221350.013
sensory perceptionGO:00076001030.013
cation transmembrane transportGO:00986552380.013
positive regulation of cytokine productionGO:00018191670.013
regulation of ion transmembrane transportGO:00347651320.013
microtubule based processGO:00070172100.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
cell migration involved in gastrulationGO:004207410.013
protein localization to nucleusGO:00345041360.013
dna repairGO:00062811980.012
regulation of wnt signaling pathwayGO:00301111230.012
regulation of apoptotic signaling pathwayGO:20012331750.012
taxisGO:00423301570.012
positive regulation of nucleoside metabolic processGO:00459791860.012
regulation of nucleotide catabolic processGO:00308112050.012
epithelial cell proliferationGO:00506731280.012
erk1 and erk2 cascadeGO:00703711040.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of ras protein signal transductionGO:00465781550.012
regulation of protein catabolic processGO:00421761550.012
cell morphogenesis involved in differentiationGO:00009041440.012
reactive oxygen species metabolic processGO:0072593750.012
positive regulation of cell motilityGO:20001471770.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
proteasomal protein catabolic processGO:00104981760.012
osteoblast differentiationGO:0001649920.012
nucleoside phosphate biosynthetic processGO:19012931090.012
cellular response to hormone stimulusGO:00328701250.012
lipid transportGO:0006869900.012
muscle structure developmentGO:0061061980.012
regulation of gtpase activityGO:00430871800.012
visual behaviorGO:000763220.012
neuron differentiationGO:00301821380.012
chromatin organizationGO:00063253510.012
neural tube closureGO:000184330.012
embryonic camera type eye developmentGO:003107620.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of dna metabolic processGO:00510521530.012
organelle assemblyGO:00709251760.012
defense response to fungusGO:005083240.012
reactive nitrogen species metabolic processGO:200105730.012
regulation of cytoskeleton organizationGO:00514931770.012
visual learningGO:000854210.012
cell cycle phase transitionGO:00447701730.012
purine containing compound biosynthetic processGO:0072522880.012
negative regulation of cell migrationGO:00303361020.012
negative regulation of cell cycleGO:00457861930.012
cellular calcium ion homeostasisGO:00068741170.012
positive regulation of cell migrationGO:00303351720.012
carboxylic acid biosynthetic processGO:0046394970.012
mitotic cell cycle phase transitionGO:00447721620.012
regulation of gtp catabolic processGO:00331241800.012
actin mediated cell contractionGO:0070252120.012
regulation of meiotic cell cycleGO:005144540.012
chemotaxisGO:00069351570.012
organelle fissionGO:00482851490.012
generation of neuronsGO:00486991520.012
atp metabolic processGO:00460341760.012
head developmentGO:00603221080.012
protein localization to membraneGO:00726571600.012
regulation of synaptic plasticityGO:004816730.012
cell cell signalingGO:00072671550.012
patterning of blood vesselsGO:000156920.012
gastrulation with mouth forming secondGO:000170210.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
negative regulation of canonical wnt signaling pathwayGO:0090090550.011
regulation of calcium ion transportGO:0051924790.011
hemopoiesisGO:00300971800.011
cellular response to cytokine stimulusGO:00713451810.011
positive regulation of gtp catabolic processGO:00331261660.011
matingGO:000761810.011
cell type specific apoptotic processGO:00972851250.011
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.011
positive regulation of cellular component biogenesisGO:00440891580.011
sensory perception of painGO:001923340.011
single organism cell adhesionGO:00986021790.011
nucleoside monophosphate metabolic processGO:00091231910.011
positive regulation of proteolysisGO:00458621420.011
positive regulation of map kinase activityGO:0043406800.011
rna processingGO:00063962550.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
single organismal cell cell adhesionGO:00163371480.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
positive regulation of hormone biosynthetic processGO:004688640.011
forebrain neuron differentiationGO:002187930.011
organic acid biosynthetic processGO:0016053970.011
rna interferenceGO:001624640.011
negative regulation of wnt signaling pathwayGO:0030178690.011
tissue morphogenesisGO:0048729960.011
covalent chromatin modificationGO:00165692540.011
multicellular organismal homeostasisGO:0048871670.011
protein importGO:00170381300.011
cerebellum developmentGO:002154920.011
positive regulation of cell cycle processGO:00900681060.011
negative regulation of kinase activityGO:00336731060.011
establishment of protein localization to organelleGO:00725941720.011
hindlimb morphogenesisGO:003513720.011
response to axon injuryGO:004867810.011
hair follicle morphogenesisGO:003106920.011
positive regulation of ion transportGO:0043270870.011
monocarboxylic acid metabolic processGO:00327871850.011
positive regulation of gtpase activityGO:00435471660.011
negative regulation of immune system processGO:00026831360.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
protein oligomerizationGO:00512591730.011
establishment of protein localization to membraneGO:00901501210.011
ubiquitin dependent protein catabolic processGO:00065112060.011
morphogenesis of a polarized epitheliumGO:000173830.011
chromatin modificationGO:00165682980.011
positive regulation of immune responseGO:00507781590.011
ribonucleotide biosynthetic processGO:0009260810.011
inorganic ion transmembrane transportGO:00986602310.011
regulation of bindingGO:00510981110.011
mitochondrion organizationGO:00070051560.011
behaviorGO:00076101120.011
sex determinationGO:000753030.011
tube developmentGO:00352951250.011
regulation of protein complex assemblyGO:00432541470.011
myoblast fusionGO:000752010.011
inorganic cation transmembrane transportGO:00986621940.011
astrocyte differentiationGO:004870840.011
regulation of actin filament based processGO:00329701410.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
regulation of epithelial cell proliferationGO:00506781130.011
negative regulation of protein kinase activityGO:0006469980.011
response to woundingGO:00096111680.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
cell activationGO:00017752130.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
g protein coupled receptor signaling pathwayGO:00071862070.011
brain developmentGO:0007420970.011
multi organism cellular processGO:00447641560.011
nuclear importGO:00511701060.011
muscle system processGO:0003012810.010
mesenchyme developmentGO:0060485590.010
negative regulation of endopeptidase activityGO:0010951840.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010
neural crest cell developmentGO:001403230.010
detection of stimulusGO:0051606850.010
cell substrate adhesionGO:00315891320.010
anatomical structure homeostasisGO:00602491000.010
regulation of growthGO:00400081650.010
microtubule cytoskeleton organizationGO:00002261760.010

SOST disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.051
nervous system diseaseDOID:8634310.037
sensory system diseaseDOID:00501552030.037
eye diseaseDOID:56141490.037
eye and adnexa diseaseDOID:14921500.037
disease of metabolismDOID:00146672950.035
inherited metabolic disorderDOID:6552420.031
connective tissue diseaseDOID:651090.026
retinal diseaseDOID:56791180.023
bone diseaseDOID:0080001880.022
central nervous system diseaseDOID:3311860.017
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.014
organ system cancerDOID:00506861640.014
myopathyDOID:4231040.014
neurodegenerative diseaseDOID:12891020.012
cardiovascular system diseaseDOID:12871060.012
immune system diseaseDOID:29141550.011