Homo sapiens

192 known processes

MADD

MAP-kinase activating death domain

(Aliases: IG20,KIAA0358,DENN,FLJ36300,RAB3GEP,FLJ35600)

MADD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glycosyl compound catabolic processGO:19016584130.210
nucleoside catabolic processGO:00091644080.193
small gtpase mediated signal transductionGO:0007264780.183
organophosphate catabolic processGO:00464344300.183
purine nucleoside triphosphate catabolic processGO:00091463920.174
purine ribonucleoside metabolic processGO:00461284370.168
purine nucleoside catabolic processGO:00061523980.161
ribonucleoside triphosphate metabolic processGO:00091994120.156
vesicle mediated transportGO:00161923710.135
ribonucleoside catabolic processGO:00424544060.123
guanosine containing compound metabolic processGO:19010682440.123
segmentationGO:003528240.121
purine nucleoside triphosphate metabolic processGO:00091444120.120
regulation of cellular ketone metabolic processGO:0010565500.119
purine ribonucleoside triphosphate catabolic processGO:00092073910.116
purine ribonucleotide catabolic processGO:00091544040.112
purine containing compound catabolic processGO:00725234110.109
purine ribonucleoside catabolic processGO:00461303980.106
guanosine containing compound catabolic processGO:19010692390.102
nucleoside triphosphate catabolic processGO:00091433940.099
lipid metabolic processGO:00066293810.099
nucleotide catabolic processGO:00091664080.096
gtp catabolic processGO:00061842370.095
regulation of gtpase activityGO:00430871800.094
gtp metabolic processGO:00460392390.089
positive regulation of gtpase activityGO:00435471660.088
ribonucleoside triphosphate catabolic processGO:00092033910.086
positive regulation of cellular amino acid metabolic processGO:004576430.081
regulation of cellular amine metabolic processGO:0033238110.081
positive regulation of hydrolase activityGO:00513453310.080
cellular amino acid metabolic processGO:00065201160.079
amine metabolic processGO:0009308440.078
ribonucleotide catabolic processGO:00092614050.078
nucleoside phosphate catabolic processGO:19012924120.077
cellular amine metabolic processGO:0044106410.074
cellular ketone metabolic processGO:0042180800.074
post embryonic developmentGO:000979120.073
ras protein signal transductionGO:0007265730.073
positive regulation of purine nucleotide metabolic processGO:19005442270.071
nucleoside triphosphate metabolic processGO:00091414220.070
positive regulation of purine nucleotide catabolic processGO:00331231850.070
cell cell signalingGO:00072671550.069
Rat
positive regulation of cellular catabolic processGO:00313312840.067
positive regulation of nucleotide catabolic processGO:00308131850.065
cellular macromolecular complex assemblyGO:00346223240.065
regulation of nucleoside metabolic processGO:00091182090.064
cellular lipid metabolic processGO:00442553030.063
generation of neuronsGO:00486991520.063
regulation of cellular amino acid metabolic processGO:000652160.062
chromatin organizationGO:00063253510.061
endomembrane system organizationGO:00102561960.060
purine ribonucleoside triphosphate metabolic processGO:00092054110.060
regulation of ras protein signal transductionGO:00465781550.059
regulation of purine nucleotide metabolic processGO:19005422640.059
positive regulation of neural precursor cell proliferationGO:200017920.058
negative regulation of catalytic activityGO:00430863350.058
positive regulation of nucleoside metabolic processGO:00459791860.057
regulation of gtp catabolic processGO:00331241800.055
memoryGO:000761330.052
regulation of nucleotide metabolic processGO:00061402690.052
positive regulation of nucleotide metabolic processGO:00459812300.051
cell projection organizationGO:00300302520.048
mitotic cell cycle processGO:19030472860.047
positive regulation of cellular amine metabolic processGO:003324070.047
regulation of cell cycleGO:00517263930.047
regulation of purine nucleotide catabolic processGO:00331212050.047
regulation of small gtpase mediated signal transductionGO:00510561560.044
purine nucleotide catabolic processGO:00061954050.044
positive regulation of gtp catabolic processGO:00331261660.043
membrane organizationGO:00610242920.041
secretionGO:00469032540.041
Rat
negative regulation of protein metabolic processGO:00512483910.040
covalent chromatin modificationGO:00165692540.040
negative regulation of programmed cell deathGO:00430693210.037
Mouse
determination of adult lifespanGO:000834020.037
cytoplasmic transportGO:00164823790.036
blastoderm segmentationGO:000735020.035
cell developmentGO:00484683280.035
endosomal transportGO:00161971290.035
organophosphate biosynthetic processGO:00904071630.035
glycerolipid metabolic processGO:00464861070.034
positive regulation of rab gtpase activityGO:0032851390.034
negative regulation of phosphate metabolic processGO:00459362670.034
positive regulation of cell proliferationGO:00082843010.033
negative regulation of cellular protein metabolic processGO:00322693530.033
single organism cellular localizationGO:19025803320.032
multicellular organismal agingGO:001025930.032
cell cycle phase transitionGO:00447701730.032
cellular component morphogenesisGO:00329893140.032
positive regulation of transportGO:00510503360.032
golgi organizationGO:0007030380.032
female gamete generationGO:000729220.032
cell morphogenesisGO:00009022960.031
chromatin modificationGO:00165682980.031
positive regulation of catabolic processGO:00098963100.031
negative regulation of cell deathGO:00605483450.031
Mouse
rhythmic behaviorGO:000762220.031
positive regulation of cellular component organizationGO:00511303760.031
chemical homeostasisGO:00488783060.031
g protein coupled receptor signaling pathwayGO:00071862070.031
neurological system processGO:00508771630.030
negative regulation of cellular component organizationGO:00511292350.030
negative regulation of hydrolase activityGO:00513461820.030
neuromuscular junction developmentGO:000752830.030
mitotic cell cycleGO:00002783260.030
nucleoside monophosphate metabolic processGO:00091231910.030
immune responseGO:00069553070.029
negative regulation of developmental processGO:00510932470.029
regulation of cell cycle processGO:00105642660.029
ribonucleoside monophosphate metabolic processGO:00091611870.028
histone modificationGO:00165702510.028
regulation of secretionGO:00510461940.028
Rat
rho protein signal transductionGO:0007266260.028
actin filament based processGO:00300292240.028
circadian sleep wake cycle processGO:002241020.028
dephosphorylationGO:00163112090.028
small molecule biosynthetic processGO:00442831570.028
regulation of neural precursor cell proliferationGO:200017740.027
regulation of body fluid levelsGO:0050878990.027
Rat
regulation of cell differentiationGO:00455953930.027
regulation of nucleotide catabolic processGO:00308112050.027
cellular macromolecule catabolic processGO:00442653800.027
mitotic cell cycle phase transitionGO:00447721620.027
nervous system developmentGO:00073992930.027
protein catabolic processGO:00301633250.026
phospholipid metabolic processGO:0006644990.026
golgi vesicle transportGO:0048193800.026
cellular response to dna damage stimulusGO:00069743790.025
regulation of growthGO:00400081650.025
system processGO:00030083490.025
Rat
lipid biosynthetic processGO:00086101770.024
single organism carbohydrate metabolic processGO:00447231930.024
organic hydroxy compound metabolic processGO:19016151470.024
regulation of ras gtpase activityGO:00323181280.024
endoplasmic reticulum organizationGO:0007029200.024
neuron differentiationGO:00301821380.024
protein modification by small protein conjugationGO:00324463420.024
regulation of circadian sleep wake cycle sleepGO:004518720.024
establishment of protein localization to membraneGO:00901501210.023
actin cytoskeleton organizationGO:00300362070.023
g1 s transition of mitotic cell cycleGO:0000082780.023
cellular protein catabolic processGO:00442572610.023
single organism membrane organizationGO:00448022680.023
cranial nerve developmentGO:002154540.023
purine ribonucleoside monophosphate metabolic processGO:00091671860.023
positive regulation of phosphorylationGO:00423273940.023
glycerophospholipid metabolic processGO:0006650840.022
negative regulation of protein modification processGO:00314002000.022
brain morphogenesisGO:004885410.022
positive regulation of protein phosphorylationGO:00019343130.022
neuroblast proliferationGO:000740540.022
response to abiotic stimulusGO:00096283360.022
cellular protein complex assemblyGO:00436231880.022
taxisGO:00423301570.022
signal transduction by phosphorylationGO:00230142970.022
circadian behaviorGO:004851220.021
regulation of circadian sleep wake cycleGO:004274920.021
morphogenesis of embryonic epitheliumGO:001633140.021
innate immune responseGO:00450871780.021
microtubule cytoskeleton organizationGO:00002261760.021
locomotory behaviorGO:000762610.021
response to organic cyclic compoundGO:00140702040.021
carbohydrate metabolic processGO:00059752070.021
growthGO:00400072020.021
endocytosisGO:00068971590.021
sensory perception of painGO:001923340.021
nerve developmentGO:002167540.021
oogenesisGO:004847720.020
negative regulation of phosphorus metabolic processGO:00105632670.020
positive regulation of ras gtpase activityGO:00323201170.020
monocarboxylic acid metabolic processGO:00327871850.020
regulation of cell morphogenesisGO:00226041530.020
circadian sleep wake cycleGO:004274520.020
regulation of rab gtpase activityGO:0032313390.020
matingGO:000761810.020
microtubule based processGO:00070172100.020
response to organonitrogen compoundGO:00102431560.020
long term memoryGO:000761620.020
secretion by cellGO:00329402260.019
Rat
regulation of kinase activityGO:00435493140.019
regulation of cellular component biogenesisGO:00440872810.019
regulation of mitotic cell cycleGO:00073461890.019
protein maturationGO:00516042330.019
spermatid developmentGO:000728640.019
regulation of cell projection organizationGO:00313441070.019
regulation of proteolysisGO:00301622930.019
ribonucleoprotein complex biogenesisGO:00226131160.019
nitrogen compound transportGO:00717051910.019
Rat
epithelium developmentGO:00604292270.019
negative regulation of apoptotic processGO:00430663160.018
Mouse
neurogenesisGO:00220081690.018
regulation of dna metabolic processGO:00510521530.018
positive regulation of organelle organizationGO:00106381950.018
organonitrogen compound biosynthetic processGO:19015662000.018
cell morphogenesis involved in differentiationGO:00009041440.018
regulation of behaviorGO:0050795820.018
regulation of cellular component movementGO:00512703340.018
carbohydrate derivative biosynthetic processGO:19011372070.018
defense responseGO:00069523150.018
regulation of neurogenesisGO:0050767820.017
regulation of anatomical structure morphogenesisGO:00226032860.017
circadian sleep wake cycle sleepGO:005080220.017
positive regulation of programmed cell deathGO:00430682490.017
sleepGO:003043120.017
negative regulation of multicellular organismal processGO:00512413170.017
Rat
protein modification by small protein removalGO:0070646920.017
central nervous system developmentGO:00074171230.017
regulation of transferase activityGO:00513383550.017
actin filament organizationGO:00070151280.017
atp metabolic processGO:00460341760.017
cell projection assemblyGO:00300311260.017
positive regulation of synaptic transmissionGO:005080640.017
regulation of synaptic plasticityGO:004816730.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
oocyte developmentGO:004859910.016
regulation of protein serine threonine kinase activityGO:00719001790.016
regulation of establishment of protein localizationGO:00702012420.016
Rat
negative regulation of cellular amine metabolic processGO:003323930.016
negative regulation of organelle organizationGO:00106391260.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
protein processingGO:00164852260.016
response to oxidative stressGO:00069791210.016
ion homeostasisGO:00508012300.016
negative regulation of phosphatase activityGO:0010923610.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
cell cycle g1 s phase transitionGO:0044843800.016
neuron projection developmentGO:00311751060.016
sensory perceptionGO:00076001030.015
positive regulation of transferase activityGO:00513472270.015
anterior posterior axis specificationGO:000994820.015
regulation of dephosphorylationGO:0035303960.015
transmembrane transportGO:00550853990.015
inorganic ion transmembrane transportGO:00986602310.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
behaviorGO:00076101120.015
maintenance of locationGO:00512351120.015
vasculature developmentGO:00019441810.015
posttranscriptional regulation of gene expressionGO:00106082130.015
apoptotic signaling pathwayGO:00971902680.015
response to decreased oxygen levelsGO:0036293960.015
positive regulation of apoptotic processGO:00430652460.015
mrna metabolic processGO:00160711750.015
spermatid differentiationGO:004851540.015
protein localization to membraneGO:00726571600.015
regulation of chromosome organizationGO:00330441030.015
regulation of endopeptidase activityGO:00525481700.015
neuron developmentGO:00486661130.015
regenerationGO:003109940.015
response to biotic stimulusGO:00096072760.015
regulation of nervous system developmentGO:0051960880.014
regulation of cell developmentGO:00602841610.014
protein deubiquitinationGO:0016579790.014
chemotaxisGO:00069351570.014
negative regulation of cell migrationGO:00303361020.014
regulation of vesicle mediated transportGO:00606271300.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
negative regulation of cellular component movementGO:00512711060.014
steroid metabolic processGO:0008202940.014
dna conformation changeGO:00711031130.014
regulation of cell cycle phase transitionGO:19019871260.014
regulation of secretion by cellGO:19035301770.014
Rat
immune system developmentGO:00025201950.014
cation homeostasisGO:00550801890.014
positive regulation of secretionGO:00510471160.013
cellular component disassemblyGO:0022411920.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of cell migrationGO:00303342890.013
positive regulation of immune system processGO:00026842830.013
response to external biotic stimulusGO:00432072610.013
regulation of peptidase activityGO:00525471800.013
mitotic nuclear divisionGO:00070671190.013
peripheral nervous system developmentGO:000742220.013
regulation of protein kinase activityGO:00458592890.013
alcohol metabolic processGO:00060661140.013
ion transmembrane transportGO:00342203380.013
tube developmentGO:00352951250.013
lipid modificationGO:0030258840.013
proteasomal protein catabolic processGO:00104981760.013
circulatory system developmentGO:00723592620.013
dna packagingGO:0006323770.013
protein ubiquitinationGO:00165673140.013
response to oxygen containing compoundGO:19017003690.013
autophagyGO:0006914880.013
associative learningGO:000830610.013
negative regulation of cell differentiationGO:00455961710.013
cellular homeostasisGO:00197251960.013
negative regulation of cell cycle processGO:00109481210.013
organic hydroxy compound biosynthetic processGO:1901617710.012
cell chemotaxisGO:00603261120.012
response to hormoneGO:00097251750.012
anterior posterior axis specification embryoGO:000859520.012
response to growth factorGO:00708482050.012
regulation of phosphatase activityGO:0010921810.012
negative regulation of phosphorylationGO:00423261740.012
regulation of cell growthGO:00015581350.012
positive regulation of cell deathGO:00109422630.012
inner ear morphogenesisGO:004247240.012
regulation of neuron differentiationGO:0045664700.012
cell part morphogenesisGO:00329901370.012
macromolecule methylationGO:0043414970.012
cellular protein complex disassemblyGO:0043624360.012
peptidyl lysine modificationGO:00182051440.012
response to other organismGO:00517072610.012
biological adhesionGO:00226103310.012
cell growthGO:00160491600.012
epithelial cell migrationGO:00106311190.012
phosphatidylinositol metabolic processGO:0046488530.012
chromatin assembly or disassemblyGO:0006333780.012
regulation of cellular response to stressGO:00801352440.012
regulation of locomotionGO:00400123290.012
rna processingGO:00063962550.012
regulation of protein processingGO:00706131500.012
regulation of protein complex assemblyGO:00432541470.012
response to fungusGO:000962040.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
response to inorganic substanceGO:00100351270.012
leukocyte activationGO:00453211640.011
regulation of protein maturationGO:19033171500.011
negative regulation of cell developmentGO:0010721480.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
visual behaviorGO:000763220.011
regulation of response to external stimulusGO:00321012220.011
ameboidal type cell migrationGO:00016671350.011
embryonic epithelial tube formationGO:000183840.011
fatty acid metabolic processGO:00066311150.011
oocyte differentiationGO:000999420.011
positive regulation of kinase activityGO:00336742040.011
tripartite regional subdivisionGO:000735120.011
somatic muscle developmentGO:000752510.011
intracellular protein transportGO:00068862700.011
peptidyl tyrosine phosphorylationGO:00181081700.011
positive regulation of cellular component biogenesisGO:00440891580.011
short term memoryGO:000761410.011
regulation of protein transportGO:00512232130.011
Rat
regulation of rho protein signal transductionGO:0035023790.011
positive regulation of cell developmentGO:0010720920.011
regulation of system processGO:00440571010.011
Rat
hindbrain developmentGO:003090230.011
negative regulation of axonogenesisGO:005077140.011
protein targetingGO:00066051870.011
adult locomotory behaviorGO:000834410.011
regulation of response to dna damage stimulusGO:2001020940.011
actin filament based movementGO:0030048170.011
nucleoside monophosphate catabolic processGO:00091251590.011
regulation of protein localizationGO:00328802960.011
Rat
response to nitrogen compoundGO:19016981840.011
rna splicingGO:00083801310.011
response to hypoxiaGO:0001666960.011
negative regulation of cell cycleGO:00457861930.011
response to oxygen levelsGO:00704821000.011
protein dna complex subunit organizationGO:0071824800.011
mrna processingGO:00063971330.011
positive regulation of mapk cascadeGO:00434101900.011
cellular response to growth factor stimulusGO:00713631970.011
regulation of immune responseGO:00507762010.010
cellular response to oxidative stressGO:0034599850.010
negative regulation of protein processingGO:00109551420.010
negative regulation of protein maturationGO:19033181420.010
regulation of defense responseGO:00313471540.010
carboxylic acid biosynthetic processGO:0046394970.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
negative regulation of dephosphorylationGO:0035305630.010
cardiovascular system developmentGO:00723582620.010
hemopoiesisGO:00300971800.010
negative regulation of cell cycle phase transitionGO:1901988890.010
atp catabolic processGO:00062001570.010
cytokine productionGO:00018162470.010
protein localization to plasma membraneGO:0072659930.010
i kappab kinase nf kappab signalingGO:00072491660.010
negative regulation of mitotic cell cycleGO:00459301020.010
visual learningGO:000854210.010
organelle assemblyGO:00709251760.010
cell projection morphogenesisGO:00488581290.010
cell divisionGO:00513011680.010
metal ion transportGO:00300012720.010
methylationGO:00322591060.010

MADD disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of mental healthDOID:150700.041
central nervous system diseaseDOID:3311860.028
nervous system diseaseDOID:8634310.028
Human
neurodegenerative diseaseDOID:12891020.015
disease of metabolismDOID:00146672950.010
musculoskeletal system diseaseDOID:172230.010