Homo sapiens

41 known processes

EXO1

exonuclease 1

(Aliases: HEX1,hExoI)

EXO1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811980.978
cellular response to dna damage stimulusGO:00069743790.889
double strand break repair via homologous recombinationGO:0000724500.826
nuclear divisionGO:00002801280.705
dna recombinationGO:0006310770.690
atp catabolic processGO:00062001570.683
recombinational repairGO:0000725500.651
nucleotide excision repairGO:0006289310.569
double strand break repairGO:00063021010.539
Yeast
cellular macromolecule catabolic processGO:00442653800.494
organelle fissionGO:00482851490.469
mismatch repairGO:0006298150.402
nucleoside monophosphate metabolic processGO:00091231910.376
nucleoside triphosphate metabolic processGO:00091414220.315
post embryonic developmentGO:000979120.260
meiosis iGO:000712740.256
ribonucleoside triphosphate metabolic processGO:00091994120.246
mitotic cell cycle phase transitionGO:00447721620.231
regulation of dna metabolic processGO:00510521530.220
purine nucleotide catabolic processGO:00061954050.219
purine nucleoside monophosphate metabolic processGO:00091261860.210
nucleoside phosphate catabolic processGO:19012924120.205
dna integrity checkpointGO:0031570710.192
purine ribonucleoside monophosphate metabolic processGO:00091671860.188
g2 dna damage checkpointGO:0031572260.184
ribonucleotide catabolic processGO:00092614050.182
purine nucleoside catabolic processGO:00061523980.175
anatomical structure homeostasisGO:00602491000.157
Yeast
chromosome segregationGO:00070591140.155
nucleic acid phosphodiester bond hydrolysisGO:00903051020.154
ribonucleoside monophosphate metabolic processGO:00091611870.148
female gamete generationGO:000729220.147
dna biosynthetic processGO:0071897400.147
dna geometric changeGO:0032392320.140
mitotic cell cycle checkpointGO:0007093680.135
dna catabolic processGO:0006308490.135
atp metabolic processGO:00460341760.126
purine ribonucleoside monophosphate catabolic processGO:00091691580.119
organophosphate catabolic processGO:00464344300.118
ribonucleoside triphosphate catabolic processGO:00092033910.116
negative regulation of dna recombinationGO:004591060.113
purine ribonucleoside metabolic processGO:00461284370.110
negative regulation of cell deathGO:00605483450.110
regulation of cell cycleGO:00517263930.108
dna dependent dna replicationGO:0006261440.108
positive regulation of hydrolase activityGO:00513453310.107
dna replicationGO:00062601160.106
nucleoside monophosphate catabolic processGO:00091251590.104
embryo developmentGO:00097901230.103
isotype switchingGO:004519030.101
Mouse
cell cycle phase transitionGO:00447701730.099
microtubule based processGO:00070172100.098
cell divisionGO:00513011680.097
purine containing compound catabolic processGO:00725234110.096
ribonucleoside monophosphate catabolic processGO:00091581580.096
purine nucleoside triphosphate catabolic processGO:00091463920.093
dna conformation changeGO:00711031130.090
immune responseGO:00069553070.089
Mouse
sex determinationGO:000753030.088
Yeast
double strand break repair via single strand annealingGO:004500240.086
meiotic nuclear divisionGO:0007126100.086
purine ribonucleoside catabolic processGO:00461303980.085
nucleoside triphosphate catabolic processGO:00091433940.085
purine ribonucleoside triphosphate metabolic processGO:00092054110.084
lymphocyte activationGO:00466491330.083
Mouse
response to uvGO:0009411730.081
response to abiotic stimulusGO:00096283360.078
purine ribonucleoside triphosphate catabolic processGO:00092073910.077
negative regulation of apoptotic processGO:00430663160.072
glycosyl compound catabolic processGO:19016584130.071
response to radiationGO:00093141510.069
maintenance of dna repeat elementsGO:004357040.069
immune system developmentGO:00025201950.068
Mouse
mitotic dna integrity checkpointGO:0044774300.067
cell developmentGO:00484683280.067
regulation of cell cycle phase transitionGO:19019871260.067
vesicle mediated transportGO:00161923710.067
somatic diversification of immune receptors via somatic mutationGO:000256610.065
Mouse
negative regulation of mitotic cell cycle phase transitionGO:1901991850.062
mitotic cell cycleGO:00002783260.062
intrinsic apoptotic signaling pathwayGO:00971931270.059
meiotic cell cycleGO:0051321130.059
Yeast
mitotic dna damage checkpointGO:0044773280.058
dna damage checkpointGO:0000077680.056
protein catabolic processGO:00301633250.056
regulation of dna recombinationGO:0000018230.054
leukocyte activationGO:00453211640.052
Mouse
negative regulation of cell cycle processGO:00109481210.052
regulation of double strand break repairGO:2000779220.051
negative regulation of mitotic cell cycleGO:00459301020.050
cellular protein catabolic processGO:00442572610.048
non recombinational repairGO:0000726140.048
negative regulation of programmed cell deathGO:00430693210.048
dna duplex unwindingGO:0032508300.047
response to light stimulusGO:0009416870.047
dna double strand break processingGO:0000729100.046
Yeast
chromosome separationGO:0051304230.045
determination of adult lifespanGO:000834020.045
oogenesisGO:004847720.043
nucleotide catabolic processGO:00091664080.042
meiotic chromosome segregationGO:004513240.042
gene conversionGO:003582210.042
Yeast
cell activation involved in immune responseGO:0002263300.041
Mouse
negative regulation of cell cycle phase transitionGO:1901988890.040
purine ribonucleotide catabolic processGO:00091544040.040
cellular response to endogenous stimulusGO:00714953360.040
apoptotic signaling pathwayGO:00971902680.038
regulation of cellular ketone metabolic processGO:0010565500.038
sister chromatid segregationGO:0000819540.037
translesion synthesisGO:001998580.036
mitochondrion organizationGO:00070051560.035
purine nucleoside triphosphate metabolic processGO:00091444120.035
negative regulation of cellular protein metabolic processGO:00322693530.035
response to oxygen containing compoundGO:19017003690.034
positive regulation of programmed cell deathGO:00430682490.033
regulation of protein catabolic processGO:00421761550.033
organophosphate biosynthetic processGO:00904071630.033
regulation of mitotic cell cycleGO:00073461890.033
nucleotide biosynthetic processGO:00091651090.033
nucleoside catabolic processGO:00091644080.032
dephosphorylationGO:00163112090.032
cell activationGO:00017752130.032
Mouse
regulation of cell cycle processGO:00105642660.032
multicellular organismal agingGO:001025930.032
developmental process involved in reproductionGO:0003006660.030
Yeast
base excision repairGO:0006284210.029
negative regulation of phosphate metabolic processGO:00459362670.029
negative regulation of catalytic activityGO:00430863350.029
postreplication repairGO:0006301120.028
dna catabolic process exonucleolyticGO:0000738170.028
positive regulation of catabolic processGO:00098963100.028
mitotic recombinationGO:000631280.027
Yeast
negative regulation of protein maturationGO:19033181420.027
mitotic cell cycle processGO:19030472860.027
reproductive processGO:00224141060.027
Yeast
single organism reproductive processGO:0044702980.026
Yeast
regulation of dna repairGO:0006282470.026
protein homooligomerizationGO:00512601000.026
male meiosisGO:000714010.025
single organism cellular localizationGO:19025803320.025
telomere maintenanceGO:0000723320.025
Yeast
positive regulation of cell deathGO:00109422630.025
protein ubiquitinationGO:00165673140.025
negative regulation of cell cycleGO:00457861930.025
single organism membrane organizationGO:00448022680.025
cell cycle checkpointGO:00000751170.025
regulation of protein maturationGO:19033171500.024
meiotic chromosome separationGO:005130730.024
asymmetric stem cell divisionGO:009872210.024
regulation of anatomical structure morphogenesisGO:00226032860.024
cell cycle arrestGO:0007050710.024
cellular protein complex assemblyGO:00436231880.024
ubiquitin dependent protein catabolic processGO:00065112060.024
positive regulation of phosphorylationGO:00423273940.023
regulation of proteolysisGO:00301622930.023
regulation of double strand break repair via homologous recombinationGO:0010569110.022
cell type specific apoptotic processGO:00972851250.022
proteolysis involved in cellular protein catabolic processGO:00516032440.022
cellular ketone metabolic processGO:0042180800.022
response to nitrogen compoundGO:19016981840.022
cilium morphogenesisGO:0060271750.021
nervous system developmentGO:00073992930.021
embryo development ending in birth or egg hatchingGO:0009792340.021
cellular component morphogenesisGO:00329893140.021
reproductionGO:0000003630.021
Yeast
meiotic cell cycle processGO:190304680.021
Yeast
reciprocal meiotic recombinationGO:000713140.021
regulation of cellular amino acid metabolic processGO:000652160.021
protein heterotetramerizationGO:005129030.020
centrosome organizationGO:0051297580.020
secretionGO:00469032540.020
covalent chromatin modificationGO:00165692540.020
cell cycle g2 m phase transitionGO:0044839430.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.019
positive regulation of cellular catabolic processGO:00313312840.019
regulation of kinase activityGO:00435493140.019
regulation of dna replicationGO:0006275680.018
somatic recombination of immunoglobulin gene segmentsGO:001644740.018
Mouse
response to organic cyclic compoundGO:00140702040.018
modification dependent macromolecule catabolic processGO:00436322120.018
growthGO:00400072020.017
immune effector processGO:00022521590.017
Mouse
positive regulation of cell proliferationGO:00082843010.017
lymphocyte differentiationGO:0030098350.017
modification dependent protein catabolic processGO:00199412090.017
receptor mediated endocytosisGO:0006898840.017
neuroblast divisionGO:005505710.017
regulation of mitotic sister chromatid segregationGO:0033047270.017
positive regulation of meiotic cell cycleGO:005144620.017
negative regulation of transferase activityGO:00513481240.016
endocytosisGO:00068971590.016
regulation of cellular amine metabolic processGO:0033238110.016
protein autophosphorylationGO:00467771230.016
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.016
Mouse
negative regulation of hydrolase activityGO:00513461820.016
ribonucleoside catabolic processGO:00424544060.016
positive regulation of immune system processGO:00026842830.016
microtubule organizing center organizationGO:0031023620.016
positive regulation of cell cycleGO:00457871400.016
regulation of endopeptidase activityGO:00525481700.016
regulation of protein localizationGO:00328802960.016
blastocyst developmentGO:000182430.016
cellular amino acid metabolic processGO:00065201160.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
cellular response to organonitrogen compoundGO:00714171240.015
leukocyte differentiationGO:0002521980.015
carbohydrate derivative biosynthetic processGO:19011372070.015
negative regulation of protein metabolic processGO:00512483910.015
nucleoside phosphate biosynthetic processGO:19012931090.015
multicellular organism reproductionGO:0032504420.015
regulation of t cell activationGO:0050863770.015
cell projection organizationGO:00300302520.015
positive regulation of apoptotic processGO:00430652460.015
cytoplasmic transportGO:00164823790.015
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.015
response to inorganic substanceGO:00100351270.015
chemical homeostasisGO:00488783060.015
regenerationGO:003109940.014
cell fate determinationGO:000170930.014
multi organism reproductive processGO:0044703540.014
regulation of mitotic cell cycle phase transitionGO:19019901180.014
proteasomal protein catabolic processGO:00104981760.014
interstrand cross link repairGO:003629730.014
cellular response to growth factor stimulusGO:00713631970.014
g2 m transition of mitotic cell cycleGO:0000086410.013
membrane organizationGO:00610242920.013
reactive oxygen species metabolic processGO:0072593750.013
amine metabolic processGO:0009308440.013
positive regulation of kinase activityGO:00336742040.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
neurogenesisGO:00220081690.013
protein processingGO:00164852260.013
protein acylationGO:00435431380.013
response to biotic stimulusGO:00096072760.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
regulation of protein kinase activityGO:00458592890.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
cell projection assemblyGO:00300311260.012
cellular response to radiationGO:0071478650.012
positive regulation of developmental processGO:00510943140.012
positive regulation of cell cycle processGO:00900681060.012
defense responseGO:00069523150.012
system processGO:00030083490.012
response to purine containing compoundGO:0014074400.012
negative regulation of cell sizeGO:004579230.012
mitotic sister chromatid cohesionGO:0007064120.012
signal transduction by phosphorylationGO:00230142970.012
regulation of bindingGO:00510981110.012
cell cycle g1 s phase transitionGO:0044843800.012
organonitrogen compound biosynthetic processGO:19015662000.012
maintenance of location in cellGO:0051651620.012
posttranscriptional regulation of gene expressionGO:00106082130.012
negative regulation of catabolic processGO:00098951040.012
cellular response to abiotic stimulusGO:00712141170.012
reciprocal dna recombinationGO:003582540.012
histone acetylationGO:0016573930.012
regulation of transferase activityGO:00513383550.011
circulatory system developmentGO:00723592620.011
actin filament based processGO:00300292240.011
maintenance of locationGO:00512351120.011
peptidyl lysine modificationGO:00182051440.011
mitotic nuclear divisionGO:00070671190.011
negative regulation of dna metabolic processGO:0051053570.011
cellular response to oxygen containing compoundGO:19017012760.011
regulation of protein processingGO:00706131500.011
cellular amine metabolic processGO:0044106410.011
regulation of neural precursor cell proliferationGO:200017740.011
cofactor metabolic processGO:0051186870.011
dna synthesis involved in dna repairGO:000073160.011
somatic hypermutation of immunoglobulin genesGO:001644610.011
Mouse
regulation of lymphocyte activationGO:00512491030.011
protein oligomerizationGO:00512591730.011
cell cell signalingGO:00072671550.011
cellular response to organic cyclic compoundGO:00714071270.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
positive regulation of organelle organizationGO:00106381950.011
negative regulation of phosphorus metabolic processGO:00105632670.011
internal protein amino acid acetylationGO:00064751010.011
multicellular organismal reproductive processGO:0048609400.011
rna processingGO:00063962550.010
oocyte developmentGO:004859910.010
protein localization to organelleGO:00333652800.010
production of molecular mediator of immune responseGO:0002440370.010
Mouse

EXO1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.294
organ system cancerDOID:00506861640.294
cancerDOID:1621670.294
breast cancerDOID:1612210.062
thoracic cancerDOID:5093210.062
immune system diseaseDOID:29141550.043
hematopoietic system diseaseDOID:741000.043
bone marrow diseaseDOID:4961310.027
anemiaDOID:2355550.012
aplastic anemiaDOID:12449300.012