Homo sapiens

0 known processes

EN2

engrailed homeobox 2

EN2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron fate commitmentGO:004866320.286
anatomical structure formation involved in morphogenesisGO:00486462840.196
Worm
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.157
Worm Fly
epithelium developmentGO:00604292270.152
Zebrafish Worm
cardiovascular system developmentGO:00723582620.121
extraocular skeletal muscle developmentGO:000207410.120
hindbrain developmentGO:003090230.110
Mouse
positive regulation of cell proliferationGO:00082843010.108
tube developmentGO:00352951250.104
Zebrafish
organ morphogenesisGO:00098871470.104
Fly
cellular ketone metabolic processGO:0042180800.103
organ formationGO:004864530.102
circulatory system developmentGO:00723592620.098
cell fate determinationGO:000170930.097
Fly
epithelial cell differentiationGO:00308551410.097
Worm
negative regulation of multicellular organismal processGO:00512413170.094
segmentationGO:003528240.092
post embryonic developmentGO:000979120.092
Fly
amine metabolic processGO:0009308440.085
regulation of cell differentiationGO:00455953930.085
nervous system developmentGO:00073992930.085
Zebrafish Mouse Fly
regulation of cellular ketone metabolic processGO:0010565500.085
specification of organ identityGO:001009230.083
cellular amine metabolic processGO:0044106410.083
negative regulation of developmental processGO:00510932470.078
positive regulation of developmental processGO:00510943140.076
enzyme linked receptor protein signaling pathwayGO:00071673030.074
secretionGO:00469032540.074
regulation of cell cycleGO:00517263930.072
cellular component morphogenesisGO:00329893140.072
Fly
cell morphogenesisGO:00009022960.071
Fly
positive regulation of cellular amine metabolic processGO:003324070.071
inner ear morphogenesisGO:004247240.071
forelimb morphogenesisGO:003513640.071
embryonic morphogenesisGO:0048598850.070
Zebrafish Worm
regulation of cellular amine metabolic processGO:0033238110.069
regulation of locomotionGO:00400123290.069
negative regulation of cell differentiationGO:00455961710.069
cellular response to endogenous stimulusGO:00714953360.069
regulation of anatomical structure morphogenesisGO:00226032860.065
vasculature developmentGO:00019441810.064
tissue morphogenesisGO:0048729960.062
tube morphogenesisGO:0035239950.062
spinal cord developmentGO:002151040.061
regulation of cellular amino acid metabolic processGO:000652160.061
forebrain regionalizationGO:002187130.060
cell developmentGO:00484683280.060
Zebrafish Mouse Fly
positive regulation of cellular amino acid metabolic processGO:004576430.060
regulation of sequence specific dna binding transcription factor activityGO:00510902110.059
cranial nerve developmentGO:002154540.058
secretion by cellGO:00329402260.057
regulation of cell motilityGO:20001452990.055
locomotory behaviorGO:000762610.055
embryonic forelimb morphogenesisGO:003511540.054
system processGO:00030083490.053
regulation of cell migrationGO:00303342890.053
morphogenesis of embryonic epitheliumGO:001633140.051
cardiac cell fate determinationGO:006091330.050
negative regulation of cell deathGO:00605483450.050
negative regulation of protein metabolic processGO:00512483910.050
stem cell differentiationGO:0048863930.049
Fly
response to oxygen containing compoundGO:19017003690.049
cellular response to oxygen containing compoundGO:19017012760.048
neuron differentiationGO:00301821380.047
Mouse Fly
mesenchymal cell differentiationGO:0048762520.047
mitotic cell cycleGO:00002783260.046
cellular amino acid metabolic processGO:00065201160.046
brain developmentGO:0007420970.046
Zebrafish Mouse Fly
forebrain generation of neuronsGO:002187230.046
defense responseGO:00069523150.045
Fly
female gamete generationGO:000729220.045
response to lipidGO:00339932060.044
regulation of cell developmentGO:00602841610.044
positive regulation of apoptotic processGO:00430652460.044
generation of neuronsGO:00486991520.043
Mouse Fly
anterior posterior axis specificationGO:000994820.043
negative regulation of cell proliferationGO:00082852280.043
positive regulation of cell deathGO:00109422630.043
mesenchyme developmentGO:0060485590.043
regulation of stem cell differentiationGO:2000736560.042
oogenesisGO:004847720.042
immune responseGO:00069553070.042
nerve developmentGO:002167540.042
cell cell signalingGO:00072671550.042
embryonic epithelial tube formationGO:000183840.041
growthGO:00400072020.041
cytoplasmic transportGO:00164823790.041
negative regulation of cellular protein metabolic processGO:00322693530.040
blood vessel developmentGO:00015681720.040
regulation of dermatome developmentGO:006118330.039
positive regulation of cell differentiationGO:00455972110.039
digestive system developmentGO:0055123750.039
cell differentiation in spinal cordGO:002151510.039
somatic stem cell maintenanceGO:003501940.039
positive regulation of aldosterone biosynthetic processGO:003234920.039
regulation of cellular component movementGO:00512703340.039
epidermis morphogenesisGO:004873030.038
positive regulation of aldosterone metabolic processGO:003234620.038
muscle structure developmentGO:0061061980.038
positive regulation of programmed cell deathGO:00430682490.038
multicellular organismal agingGO:001025930.038
mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333740.037
regulation of cytokine productionGO:00018172320.037
skeletal system developmentGO:0001501790.037
negative regulation of apoptotic processGO:00430663160.037
nitrogen compound transportGO:00717051910.037
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.037
morphogenesis of an epitheliumGO:0002009600.036
positive regulation of transportGO:00510503360.036
cellular macromolecule catabolic processGO:00442653800.036
neurogenesisGO:00220081690.036
Mouse Fly
head developmentGO:00603221080.036
Zebrafish Mouse Fly
soft palate developmentGO:006002330.036
regulation of secretionGO:00510461940.035
response to organic cyclic compoundGO:00140702040.035
motor neuron axon guidanceGO:000804520.035
transmembrane transportGO:00550853990.035
negative regulation of phosphorus metabolic processGO:00105632670.035
negative regulation of programmed cell deathGO:00430693210.034
epithelial tube morphogenesisGO:0060562380.034
determination of adult lifespanGO:000834020.034
protein localization to organelleGO:00333652800.034
limbic system developmentGO:002176130.034
mesenchymal cell developmentGO:0014031500.034
cell projection organizationGO:00300302520.034
Fly
cytokine productionGO:00018162470.034
regulation of proteolysisGO:00301622930.034
lipid metabolic processGO:00066293810.033
anion transportGO:00068201610.033
central nervous system developmentGO:00074171230.033
Zebrafish Mouse Fly
hard palate developmentGO:006002210.033
response to abiotic stimulusGO:00096283360.033
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.033
positive regulation of cellular component organizationGO:00511303760.033
cellular response to growth factor stimulusGO:00713631970.033
cell morphogenesis involved in differentiationGO:00009041440.033
Fly
blastoderm segmentationGO:000735020.032
regulation of growthGO:00400081650.032
cell adhesionGO:00071553250.032
pituitary gland developmentGO:002198320.032
digestive tract developmentGO:0048565750.032
somitogenesisGO:000175620.032
regulation of kinase activityGO:00435493140.032
negative regulation of phosphate metabolic processGO:00459362670.032
regulation of hormone levelsGO:00108171250.032
stem cell developmentGO:0048864690.032
hair follicle morphogenesisGO:003106920.032
cardiac muscle cell contractionGO:008600340.031
heart developmentGO:0007507950.031
epithelial tube branching involved in lung morphogenesisGO:006044140.031
embryo developmentGO:00097901230.031
Zebrafish Worm
hematopoietic or lymphoid organ developmentGO:00485341860.031
regulation of endopeptidase activityGO:00525481700.031
positive regulation of phosphorylationGO:00423273940.031
positive regulation of hydrolase activityGO:00513453310.031
single organism cellular localizationGO:19025803320.031
regulation of secretion by cellGO:19035301770.031
protein catabolic processGO:00301633250.031
cation transmembrane transportGO:00986552380.030
blood vessel morphogenesisGO:00485141620.030
negative regulation of catalytic activityGO:00430863350.030
mesonephric duct developmentGO:007217730.030
actin filament based processGO:00300292240.030
embryonic camera type eye developmentGO:003107620.030
immune system developmentGO:00025201950.030
regulation of peptidase activityGO:00525471800.029
vesicle mediated transportGO:00161923710.029
forebrain neuron differentiationGO:002187930.029
negative regulation of gliogenesisGO:001401430.029
intracellular protein transportGO:00068862700.029
biological adhesionGO:00226103310.029
regulation of multi organism processGO:00439001570.029
regulation of protein transportGO:00512232130.029
negative regulation of locomotionGO:00400131180.029
pancreas developmentGO:0031016190.028
regulation of cell growthGO:00015581350.028
purine ribonucleoside metabolic processGO:00461284370.028
ras protein signal transductionGO:0007265730.028
innate immune responseGO:00450871780.028
negative regulation of cell cycleGO:00457861930.028
formation of primary germ layerGO:0001704420.028
chemical homeostasisGO:00488783060.028
muscle tissue developmentGO:0060537620.028
regulation of cellular response to stressGO:00801352440.028
cardiac right ventricle morphogenesisGO:000321530.028
regulation of transferase activityGO:00513383550.028
response to nitrogen compoundGO:19016981840.027
heart formationGO:006091420.027
cell growthGO:00160491600.027
regenerationGO:003109940.027
photoreceptor cell differentiationGO:004653020.027
positive regulation of tooth mineralizationGO:007017220.027
regulation of mitotic cell cycleGO:00073461890.027
menstrual cycle phaseGO:002260120.027
positive regulation of cell cycleGO:00457871400.027
cellular response to dna damage stimulusGO:00069743790.026
negative regulation of cellular component organizationGO:00511292350.026
oxidation reduction processGO:00551143960.026
metencephalon developmentGO:002203720.026
regulation of establishment of protein localizationGO:00702012420.026
angiogenesisGO:00015251470.026
regulation of cell cycle processGO:00105642660.026
regulation of response to external stimulusGO:00321012220.026
epithelial cell proliferationGO:00506731280.026
cellular homeostasisGO:00197251960.026
positive regulation of immune system processGO:00026842830.026
regulation of neural precursor cell proliferationGO:200017740.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
thymus developmentGO:004853830.026
neuromuscular junction developmentGO:000752830.025
reproductive processGO:00224141060.025
Fly
midgut developmentGO:000749410.025
small gtpase mediated signal transductionGO:0007264780.025
cellular response to organic cyclic compoundGO:00714071270.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.025
positive regulation of cellular component movementGO:00512721810.025
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.025
ribonucleoside catabolic processGO:00424544060.025
positive regulation of protein phosphorylationGO:00019343130.025
mapk cascadeGO:00001652880.025
negative regulation of cell developmentGO:0010721480.025
carbohydrate metabolic processGO:00059752070.025
regulation of protein localizationGO:00328802960.025
neural crest cell developmentGO:001403230.025
embryonic camera type eye formationGO:006090020.025
neural tube formationGO:000184130.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
embryonic camera type eye morphogenesisGO:004859620.025
purine containing compound catabolic processGO:00725234110.025
positive regulation of neural precursor cell proliferationGO:200017920.025
nucleoside catabolic processGO:00091644080.024
purine nucleoside catabolic processGO:00061523980.024
nucleoside triphosphate metabolic processGO:00091414220.024
regulation of nucleotide metabolic processGO:00061402690.024
neuroendocrine cell differentiationGO:006110120.024
regulation of nervous system developmentGO:0051960880.024
embryonic organ developmentGO:0048568360.023
hemopoiesisGO:00300971800.023
protein modification by small protein conjugationGO:00324463420.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
cerebellum developmentGO:002154920.023
cation transportGO:00068123310.023
nucleoside triphosphate catabolic processGO:00091433940.023
heart morphogenesisGO:0003007480.023
organonitrogen compound biosynthetic processGO:19015662000.023
cellular response to lipidGO:00713961270.023
adult locomotory behaviorGO:000834410.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
pharynx developmentGO:006046510.023
cell activationGO:00017752130.023
aortic valve developmentGO:000317630.023
purine ribonucleoside catabolic processGO:00461303980.023
ameboidal type cell migrationGO:00016671350.023
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.023
endocrine system developmentGO:0035270260.023
regulation of neurogenesisGO:0050767820.023
regulation of cell morphogenesisGO:00226041530.022
response to organonitrogen compoundGO:00102431560.022
salivary gland morphogenesisGO:000743540.022
peripheral nervous system developmentGO:000742220.022
skin developmentGO:0043588760.022
Worm
cellular lipid metabolic processGO:00442553030.022
taxisGO:00423301570.022
Fly
cellular response to hormone stimulusGO:00328701250.022
hormone transportGO:0009914680.022
neuron projection developmentGO:00311751060.022
Fly
peptide transportGO:0015833740.022
negative regulation of cell growthGO:0030308830.022
negative regulation of phosphorylationGO:00423261740.022
posttranscriptional regulation of gene expressionGO:00106082130.022
negative regulation of stem cell differentiationGO:2000737220.022
nucleoside phosphate catabolic processGO:19012924120.022
cell part morphogenesisGO:00329901370.022
Fly
single organism carbohydrate metabolic processGO:00447231930.022
muscle organ developmentGO:0007517560.022
negative regulation of transportGO:00510511760.022
wnt signaling pathwayGO:00160551560.022
regulation of branching involved in ureteric bud morphogenesisGO:009018930.022
cell projection morphogenesisGO:00488581290.022
Fly
signal transduction by phosphorylationGO:00230142970.022
sex determinationGO:000753030.022
protein targetingGO:00066051870.021
response to woundingGO:00096111680.021
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
ribonucleotide catabolic processGO:00092614050.021
nucleocytoplasmic transportGO:00069131760.021
mitotic cell cycle processGO:19030472860.021
outflow tract septum morphogenesisGO:000314840.021
positive regulation of protein transportGO:00512221350.021
intracellular receptor signaling pathwayGO:00305221040.021
neuron developmentGO:00486661130.021
Mouse Fly
positive regulation of mapk cascadeGO:00434101900.021
glycosyl compound catabolic processGO:19016584130.021
membrane organizationGO:00610242920.021
Worm
pattern specification processGO:0007389430.021
Zebrafish Fly
anterior posterior axis specification embryoGO:000859520.021
cellular macromolecular complex assemblyGO:00346223240.021
embryonic viscerocranium morphogenesisGO:004870310.021
cell proliferation in forebrainGO:002184610.021
cell divisionGO:00513011680.021
sensory organ developmentGO:0007423520.021
negative regulation of growthGO:0045926970.021
establishment of protein localization to organelleGO:00725941720.021
positive regulation of cell motilityGO:20001471770.021
actin mediated cell contractionGO:0070252120.021
positive regulation of cell developmentGO:0010720920.020
embryonic organ morphogenesisGO:0048562240.020
nuclear transportGO:00511691790.020
osteoblast differentiationGO:0001649920.020
primary neural tube formationGO:001402030.020
positive regulation of organelle organizationGO:00106381950.020
luteinizing hormone secretionGO:003227510.020
response to other organismGO:00517072610.020
Fly
small molecule biosynthetic processGO:00442831570.020
hormone secretionGO:0046879650.020
astrocyte differentiationGO:004870840.020
response to hormoneGO:00097251750.020
organophosphate catabolic processGO:00464344300.020
positive regulation of catabolic processGO:00098963100.020
cellular protein catabolic processGO:00442572610.020
ion transmembrane transportGO:00342203380.020
negative regulation of cellular component movementGO:00512711060.020
neuroblast proliferationGO:000740540.020
protein ubiquitinationGO:00165673140.020
amide transportGO:0042886760.020
protein processingGO:00164852260.020
response to biotic stimulusGO:00096072760.020
Fly
negative regulation of cell migrationGO:00303361020.020
single organism reproductive processGO:0044702980.020
Fly
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.019
tripartite regional subdivisionGO:000735120.019
response to cytokineGO:00340972320.019
regulation of mapk cascadeGO:00434082620.019
regulation of epithelial cell proliferationGO:00506781130.019
regulation of neuron differentiationGO:0045664700.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
regulation of protein kinase activityGO:00458592890.019
regulation of cellular component biogenesisGO:00440872810.019
limb bud formationGO:006017410.019
response to growth factorGO:00708482050.019
positive regulation of cellular catabolic processGO:00313312840.019
nucleotide catabolic processGO:00091664080.019
ossificationGO:00015031210.019
regulation of male gonad developmentGO:200001840.019
positive regulation of cytokine productionGO:00018191670.019
reactive oxygen species metabolic processGO:0072593750.019
negative regulation of intracellular signal transductionGO:19025321830.019
epithelium migrationGO:00901321190.019
purine ribonucleotide catabolic processGO:00091544040.019
regulation of cell morphogenesis involved in differentiationGO:0010769830.019
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.019
neurological system processGO:00508771630.019
response to external biotic stimulusGO:00432072610.019
Fly
follicle stimulating hormone secretionGO:004688430.019
heart field specificationGO:000312820.019
regulation of immune responseGO:00507762010.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.019
interspecies interaction between organismsGO:00444191560.018
protein maturationGO:00516042330.018
chromatin modificationGO:00165682980.018
carbohydrate derivative biosynthetic processGO:19011372070.018
chromatin organizationGO:00063253510.018
ion homeostasisGO:00508012300.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.018
bmp signaling pathway involved in heart developmentGO:006131230.018
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.018
detection of stimulusGO:0051606850.018
cation homeostasisGO:00550801890.018
optic nerve developmentGO:002155420.018
negative regulation of mitotic cell cycleGO:00459301020.018
metal ion transportGO:00300012720.018
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
tissue regenerationGO:004224630.018
regulation of intracellular transportGO:00323861950.018
positive regulation of locomotionGO:00400171860.018
positive regulation of transferase activityGO:00513472270.018
male genitalia developmentGO:003053910.018
organic hydroxy compound metabolic processGO:19016151470.018
regulation of cysteine type endopeptidase activityGO:20001161270.018
oocyte differentiationGO:000999420.018
epidermis developmentGO:0008544590.018
Worm
glial cell migrationGO:000834740.018
positive regulation of proteolysisGO:00458621420.018
sensory perceptionGO:00076001030.018
canonical wnt signaling pathwayGO:00600701160.018
modification dependent macromolecule catabolic processGO:00436322120.018
cerebral cortex cell migrationGO:002179530.018
neuron projection regenerationGO:003110210.018
pattern specification involved in kidney developmentGO:006100410.018
positive regulation of hormone biosynthetic processGO:004688640.018
compound eye developmentGO:004874910.017
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
striated muscle tissue developmentGO:0014706590.017
positive regulation of cell migrationGO:00303351720.017
actin filament based movementGO:0030048170.017
immune effector processGO:00022521590.017
tube closureGO:006060630.017
cellular chemical homeostasisGO:00550821800.017
digestive tract morphogenesisGO:0048546560.017
oocyte developmentGO:004859910.017
tissue migrationGO:00901301190.017
cd8 positive alpha beta t cell differentiation involved in immune responseGO:000230210.017
epithelial cell migrationGO:00106311190.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
negative regulation of protein modification processGO:00314002000.017
pulmonary vein morphogenesisGO:006057710.017
purine nucleotide catabolic processGO:00061954050.017
non canonical wnt signaling pathway via mapk cascadeGO:003803040.017
neural tube patterningGO:002153220.017
Zebrafish
chemotaxisGO:00069351570.017
Fly
maintenance of locationGO:00512351120.017
multi organism cellular processGO:00447641560.017
positive regulation of nucleotide metabolic processGO:00459812300.017
cellular response to organonitrogen compoundGO:00714171240.017
memoryGO:000761330.017
negative regulation of hydrolase activityGO:00513461820.017
regulation of intracellular protein transportGO:00331571230.017
brain morphogenesisGO:004885410.016
leukocyte activationGO:00453211640.016
muscle system processGO:0003012810.016
regulation of cytoplasmic transportGO:19036491490.016
striated muscle contractionGO:0006941520.016
signal releaseGO:0023061700.016
histone modificationGO:00165702510.016
positive regulation of odontogenesisGO:004248230.016
apoptotic signaling pathwayGO:00971902680.016
single organism membrane organizationGO:00448022680.016
Worm
rho protein signal transductionGO:0007266260.016
renal system developmentGO:0072001630.016
foramen ovale closureGO:003592210.016
single organism cell adhesionGO:00986021790.016
protein localization to nucleusGO:00345041360.016
positive regulation of epithelial cell proliferationGO:0050679650.016
regulation of nucleocytoplasmic transportGO:0046822980.016
positive regulation of cysteine type endopeptidase activityGO:2001056790.016
negative regulation of cellular amine metabolic processGO:003323930.016
positive regulation of endopeptidase activityGO:0010950840.016
keratinizationGO:003142420.016
covalent chromatin modificationGO:00165692540.016
regulation of angiogenesisGO:0045765920.016
ectodermal placode developmentGO:007169610.016
ectoderm developmentGO:000739830.016
regulation of ossificationGO:0030278580.016
protein importGO:00170381300.016
guanosine containing compound catabolic processGO:19010692390.016
negative regulation of cell motilityGO:20001461040.016
metal ion homeostasisGO:00550651690.016
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.016
negative regulation of protein phosphorylationGO:00019331400.016
positive regulation of secretion by cellGO:19035321080.016
positive regulation of peptidase activityGO:0010952880.016
ubiquitin dependent protein catabolic processGO:00065112060.016
epithelial to mesenchymal transitionGO:0001837480.016
developmental programmed cell deathGO:001062330.016
Zebrafish
embryonic eye morphogenesisGO:004804820.015
gastrulationGO:0007369510.015
regulation of vasculature developmentGO:1901342970.015
cellular cation homeostasisGO:00300031630.015
modification dependent protein catabolic processGO:00199412090.015
regulation of purine nucleotide metabolic processGO:19005422640.015
gtp metabolic processGO:00460392390.015
regulation of organ formationGO:000315640.015
response to inorganic substanceGO:00100351270.015
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.015
reactive oxygen species biosynthetic processGO:190340940.015
endodermal cell fate specificationGO:000171440.015
regionalizationGO:0003002290.015
Zebrafish Fly
ventral spinal cord developmentGO:002151710.015
regulation of cardioblast differentiationGO:005189040.015
cellular component disassemblyGO:0022411920.015
gtp catabolic processGO:00061842370.015
neural tube closureGO:000184330.015
cell cycle phase transitionGO:00447701730.015
behaviorGO:00076101120.015
cell fate commitment involved in pattern specificationGO:006058110.015
regulation of neuroblast proliferationGO:190269230.015
nucleic acid phosphodiester bond hydrolysisGO:00903051020.015

EN2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.041
sensory system diseaseDOID:00501552030.041
eye and adnexa diseaseDOID:14921500.032
eye diseaseDOID:56141490.032
musculoskeletal system diseaseDOID:172230.029
disease of metabolismDOID:00146672950.028
inherited metabolic disorderDOID:6552420.022
connective tissue diseaseDOID:651090.021
bone diseaseDOID:0080001880.021
cancerDOID:1621670.020
disease of cellular proliferationDOID:145661740.020
organ system cancerDOID:00506861640.019
retinal diseaseDOID:56791180.019
central nervous system diseaseDOID:3311860.016