Homo sapiens

102 known processes

F12

coagulation factor XII (Hageman factor)

(Aliases: HAF,HAE3,HAEX)

F12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.107
oxidation reduction processGO:00551143960.079
small molecule biosynthetic processGO:00442831570.063
carboxylic acid biosynthetic processGO:0046394970.056
post embryonic developmentGO:000979120.056
cellular ketone metabolic processGO:0042180800.053
cellular lipid metabolic processGO:00442553030.052
lipid metabolic processGO:00066293810.050
monocarboxylic acid metabolic processGO:00327871850.047
organic hydroxy compound metabolic processGO:19016151470.046
organonitrogen compound biosynthetic processGO:19015662000.045
defense responseGO:00069523150.045
protein processingGO:00164852260.045
regulation of cellular amino acid metabolic processGO:000652160.043
cellular amine metabolic processGO:0044106410.043
multicellular organismal agingGO:001025930.042
chemical homeostasisGO:00488783060.041
amine metabolic processGO:0009308440.040
determination of adult lifespanGO:000834020.039
regulation of response to external stimulusGO:00321012220.039
organic acid biosynthetic processGO:0016053970.038
protein maturationGO:00516042330.037
negative regulation of protein metabolic processGO:00512483910.036
Human
ion homeostasisGO:00508012300.035
regulation of cellular amine metabolic processGO:0033238110.035
regulation of proteolysisGO:00301622930.035
Human
negative regulation of catalytic activityGO:00430863350.034
Human
positive regulation of cellular amine metabolic processGO:003324070.032
negative regulation of protein processingGO:00109551420.031
Human
cation transportGO:00068123310.030
immune responseGO:00069553070.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
negative regulation of protein maturationGO:19033181420.029
Human
purine ribonucleoside metabolic processGO:00461284370.029
lipid biosynthetic processGO:00086101770.028
wound healingGO:00420601150.028
regulation of cellular ketone metabolic processGO:0010565500.028
response to woundingGO:00096111680.028
long chain fatty acid metabolic processGO:0001676300.028
positive regulation of transportGO:00510503360.027
transmembrane transportGO:00550853990.027
oogenesisGO:004847720.027
female gamete generationGO:000729220.027
regulation of protein maturationGO:19033171500.026
small molecule catabolic processGO:0044282920.026
segmentationGO:003528240.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
protein catabolic processGO:00301633250.026
regulation of response to woundingGO:19030341010.025
ribonucleoside catabolic processGO:00424544060.025
negative regulation of cellular protein metabolic processGO:00322693530.025
Human
single organism cellular localizationGO:19025803320.025
regulation of immune responseGO:00507762010.025
cytoplasmic transportGO:00164823790.025
response to oxygen containing compoundGO:19017003690.025
Human
alcohol metabolic processGO:00060661140.025
regulation of endopeptidase activityGO:00525481700.024
Human
positive regulation of immune system processGO:00026842830.024
cellular macromolecule catabolic processGO:00442653800.024
regulation of protein localizationGO:00328802960.024
reactive oxygen species biosynthetic processGO:190340940.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
interspecies interaction between organismsGO:00444191560.024
positive regulation of catabolic processGO:00098963100.024
negative regulation of hydrolase activityGO:00513461820.023
Human
regulation of cellular component movementGO:00512703340.023
Human
purine containing compound catabolic processGO:00725234110.023
regulation of protein processingGO:00706131500.023
response to biotic stimulusGO:00096072760.023
regulation of establishment of protein localizationGO:00702012420.023
single organism membrane organizationGO:00448022680.023
system processGO:00030083490.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
nucleoside phosphate catabolic processGO:19012924120.022
negative regulation of proteolysisGO:00458611320.022
Human
cellular response to oxygen containing compoundGO:19017012760.022
Human
ribonucleoside triphosphate catabolic processGO:00092033910.022
cation homeostasisGO:00550801890.022
locomotory behaviorGO:000762610.022
positive regulation of hydrolase activityGO:00513453310.022
anion transportGO:00068201610.022
nucleoside triphosphate metabolic processGO:00091414220.021
biological adhesionGO:00226103310.021
Human
purine ribonucleotide catabolic processGO:00091544040.021
negative regulation of programmed cell deathGO:00430693210.021
Human
membrane organizationGO:00610242920.021
quinone catabolic processGO:190166220.021
actin filament based processGO:00300292240.021
organic acid transportGO:0015849650.021
organophosphate catabolic processGO:00464344300.020
negative regulation of cellular component organizationGO:00511292350.020
Human
regulation of anatomical structure morphogenesisGO:00226032860.020
Human
regulation of wound healingGO:0061041560.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
negative regulation of phosphorus metabolic processGO:00105632670.020
cytokine productionGO:00018162470.020
positive regulation of cellular catabolic processGO:00313312840.020
purine nucleoside catabolic processGO:00061523980.020
rho protein signal transductionGO:0007266260.020
vesicle mediated transportGO:00161923710.020
negative regulation of phosphate metabolic processGO:00459362670.020
coagulationGO:0050817780.020
protein modification by small protein conjugationGO:00324463420.019
protein localization to membraneGO:00726571600.019
ras protein signal transductionGO:0007265730.019
cellular protein catabolic processGO:00442572610.019
nucleoside catabolic processGO:00091644080.019
small gtpase mediated signal transductionGO:0007264780.019
nucleoside triphosphate catabolic processGO:00091433940.019
symbiosis encompassing mutualism through parasitismGO:00444031560.019
nucleotide catabolic processGO:00091664080.019
response to other organismGO:00517072610.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
mitotic cell cycleGO:00002783260.019
regulation of reactive oxygen species metabolic processGO:2000377410.019
innate immune responseGO:00450871780.019
purine nucleotide catabolic processGO:00061954050.019
purine ribonucleoside catabolic processGO:00461303980.019
carboxylic acid catabolic processGO:0046395710.019
regulation of peptidase activityGO:00525471800.019
Human
carboxylic acid transportGO:0046942630.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
steroid metabolic processGO:0008202940.018
monocarboxylic acid biosynthetic processGO:0072330670.018
cell morphogenesisGO:00009022960.018
multi organism cellular processGO:00447641560.018
fatty acid metabolic processGO:00066311150.018
alpha amino acid metabolic processGO:1901605720.018
response to fungusGO:000962040.018
secretionGO:00469032540.018
regulation of defense responseGO:00313471540.018
blood coagulationGO:0007596760.018
protein localization to organelleGO:00333652800.018
cofactor metabolic processGO:0051186870.018
immune effector processGO:00022521590.018
intracellular protein transportGO:00068862700.018
secretion by cellGO:00329402260.018
cellular macromolecular complex assemblyGO:00346223240.018
cell adhesionGO:00071553250.018
Human
glycosyl compound catabolic processGO:19016584130.018
regenerationGO:003109940.018
regulation of coagulationGO:0050818440.018
reactive nitrogen species metabolic processGO:200105730.018
negative regulation of apoptotic processGO:00430663160.018
Human
endomembrane system organizationGO:00102561960.017
metal ion transportGO:00300012720.017
carbohydrate metabolic processGO:00059752070.017
morphogenesis of embryonic epitheliumGO:001633140.017
cellular homeostasisGO:00197251960.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
regulation of cell differentiationGO:00455953930.017
cell fate determinationGO:000170930.017
sensory perception of smellGO:000760820.017
anterior posterior axis specificationGO:000994820.017
response to external biotic stimulusGO:00432072610.017
negative regulation of cellular amine metabolic processGO:003323930.017
ketone catabolic processGO:004218230.017
hindbrain developmentGO:003090230.017
negative regulation of cell deathGO:00605483450.017
Human
viral life cycleGO:00190581320.017
lipid transportGO:0006869900.017
peripheral nervous system developmentGO:000742220.017
cellular modified amino acid metabolic processGO:0006575640.017
blastoderm segmentationGO:000735020.017
defense response to fungusGO:005083240.017
protein ubiquitinationGO:00165673140.016
ribonucleotide catabolic processGO:00092614050.016
memoryGO:000761330.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
positive regulation of immune responseGO:00507781590.016
regulation of multi organism processGO:00439001570.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
regulation of cell cycleGO:00517263930.016
cellular response to dna damage stimulusGO:00069743790.016
nitrogen compound transportGO:00717051910.016
cellular response to endogenous stimulusGO:00714953360.016
negative regulation of icosanoid secretionGO:003230420.016
carbohydrate derivative biosynthetic processGO:19011372070.016
mitochondrion organizationGO:00070051560.016
Human
cellular response to hormone stimulusGO:00328701250.016
regulation of transferase activityGO:00513383550.016
regulation of cellular response to stressGO:00801352440.016
Human
dephosphorylationGO:00163112090.016
negative regulation of wnt protein secretionGO:006135810.016
viral processGO:00160321460.016
organ formationGO:004864530.016
apoptotic signaling pathwayGO:00971902680.016
Human
positive regulation of cellular component organizationGO:00511303760.015
regulation of hormone levelsGO:00108171250.015
organophosphate biosynthetic processGO:00904071630.015
reactive oxygen species metabolic processGO:0072593750.015
lipid catabolic processGO:0016042840.015
phylloquinone metabolic processGO:004237420.015
organic anion transportGO:00157111030.015
cellular calcium ion homeostasisGO:00068741170.015
single organism carbohydrate metabolic processGO:00447231930.015
nucleoside monophosphate metabolic processGO:00091231910.015
compound eye developmentGO:004874910.015
negative regulation of peptidase activityGO:0010466910.015
Human
regulation of reactive oxygen species biosynthetic processGO:190342630.015
nuclear transportGO:00511691790.015
leukotriene b4 metabolic processGO:003610220.015
neurological system processGO:00508771630.015
regulation of purine nucleotide catabolic processGO:00331212050.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
negative regulation of protein modification processGO:00314002000.015
defense response to other organismGO:00985421290.015
mitotic cell cycle processGO:19030472860.015
cellular chemical homeostasisGO:00550821800.015
cellular component morphogenesisGO:00329893140.015
modification dependent macromolecule catabolic processGO:00436322120.015
response to abiotic stimulusGO:00096283360.015
response to lipidGO:00339932060.015
oocyte developmentGO:004859910.015
epoxygenase p450 pathwayGO:001937330.015
positive regulation of secretionGO:00510471160.014
negative regulation of response to external stimulusGO:0032102830.014
regulation of protein transportGO:00512232130.014
activation of immune responseGO:00022531140.014
organic acid catabolic processGO:0016054710.014
chromatin organizationGO:00063253510.014
coenzyme metabolic processGO:0006732650.014
maintenance of locationGO:00512351120.014
inner ear morphogenesisGO:004247240.014
organic hydroxy compound biosynthetic processGO:1901617710.014
modification dependent protein catabolic processGO:00199412090.014
mapk cascadeGO:00001652880.014
regulation of neural precursor cell proliferationGO:200017740.014
regulation of locomotionGO:00400123290.014
Human
lipid localizationGO:00108761060.014
ubiquitin dependent protein catabolic processGO:00065112060.014
negative regulation of response to woundingGO:1903035470.014
protein targetingGO:00066051870.014
regulation of blood coagulationGO:0030193420.014
negative regulation of intracellular signal transductionGO:19025321830.014
establishment of protein localization to membraneGO:00901501210.014
protein oligomerizationGO:00512591730.014
oocyte differentiationGO:000999420.014
regulation of apoptotic signaling pathwayGO:20012331750.014
Human
cellular amide metabolic processGO:0043603690.014
establishment of protein localization to organelleGO:00725941720.014
posttranscriptional regulation of gene expressionGO:00106082130.014
regulation of intracellular transportGO:00323861950.014
regulation of kinase activityGO:00435493140.014
spermatid differentiationGO:004851540.014
regulation of cell cycle processGO:00105642660.014
regulation of nucleoside metabolic processGO:00091182090.014
regulation of cytoskeleton organizationGO:00514931770.014
regulation of secretionGO:00510461940.014
positive regulation of nucleotide metabolic processGO:00459812300.014
actin cytoskeleton organizationGO:00300362070.014
chromatin modificationGO:00165682980.013
metal ion homeostasisGO:00550651690.013
atp metabolic processGO:00460341760.013
photoreceptor cell differentiationGO:004653020.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
tripartite regional subdivisionGO:000735120.013
regulation of purine nucleotide metabolic processGO:19005422640.013
cell growthGO:00160491600.013
regulation of nucleotide metabolic processGO:00061402690.013
positive regulation of phosphorylationGO:00423273940.013
Human
cellular protein complex assemblyGO:00436231880.013
microtubule based processGO:00070172100.013
growthGO:00400072020.013
vitamin k catabolic processGO:004237720.013
ion transmembrane transportGO:00342203380.013
sulfur compound metabolic processGO:00067901010.013
hemostasisGO:0007599760.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
metencephalon developmentGO:002203720.013
cellular cation homeostasisGO:00300031630.013
anterior posterior axis specification embryoGO:000859520.013
cell projection organizationGO:00300302520.013
nucleocytoplasmic transportGO:00069131760.013
response to hormoneGO:00097251750.013
negative regulation of endopeptidase activityGO:0010951840.013
Human
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163510.013
regulation of protein kinase activityGO:00458592890.013
response to nitrogen compoundGO:19016981840.013
epithelium developmentGO:00604292270.013
Human
positive regulation of programmed cell deathGO:00430682490.013
proteasomal protein catabolic processGO:00104981760.013
glial cell migrationGO:000834740.013
rna processingGO:00063962550.013
response to cytokineGO:00340972320.013
syncytium formation by plasma membrane fusionGO:000076820.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of protein complex assemblyGO:00432541470.012
negative regulation of transportGO:00510511760.012
embryonic epithelial tube formationGO:000183840.012
positive regulation of ion transportGO:0043270870.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
adult locomotory behaviorGO:000834410.012
neuromuscular junction developmentGO:000752830.012
regulation of cellular component biogenesisGO:00440872810.012
regulation of body fluid levelsGO:0050878990.012
positive regulation of cell proliferationGO:00082843010.012
regulation of ion transportGO:00432691890.012
covalent chromatin modificationGO:00165692540.012
regulation of protein catabolic processGO:00421761550.012
negative regulation of phosphorylationGO:00423261740.012
negative regulation of cell cycleGO:00457861930.012
somitogenesisGO:000175620.012
nucleoside monophosphate catabolic processGO:00091251590.012
spermatid developmentGO:000728640.012
opioid receptor signaling pathwayGO:003800340.012
inorganic cation transmembrane transportGO:00986621940.012
cellular amino acid biosynthetic processGO:0008652300.012
cardiac muscle cell contractionGO:008600340.012
regulation of secretion by cellGO:19035301770.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
9 cis retinoic acid metabolic processGO:004290510.012
positive regulation of synaptic transmissionGO:005080640.012
regulation of cell motilityGO:20001452990.012
Human
cation transmembrane transportGO:00986552380.012
sequestering of metal ionGO:0051238240.012
negative regulation of cell proliferationGO:00082852280.012
regulation of nucleotide catabolic processGO:00308112050.012
cellular metal ion homeostasisGO:00068751460.012
organelle assemblyGO:00709251760.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
negative regulation of cytosolic calcium ion concentrationGO:005148110.012
sensory perceptionGO:00076001030.012
plasma membrane organizationGO:00070091150.012
regulation of gtpase activityGO:00430871800.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
actin mediated cell contractionGO:0070252120.012
protein secretionGO:0009306980.012
tissue regenerationGO:004224630.012
response to organonitrogen compoundGO:00102431560.012
cellular ion homeostasisGO:00068731680.012
i kappab kinase nf kappab signalingGO:00072491660.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
somatostatin receptor signaling pathwayGO:003816910.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
regulation of large conductance calcium activated potassium channel activityGO:190260620.011
glycerolipid metabolic processGO:00464861070.011
neural tube formationGO:000184130.011
behavioral response to ethanolGO:004814920.011
regulation of synaptic plasticityGO:004816730.011
organic hydroxy compound transportGO:0015850630.011
neural crest cell developmentGO:001403230.011
signal transduction by phosphorylationGO:00230142970.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
Human
circulatory system developmentGO:00723592620.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
divalent metal ion transportGO:00708381520.011
guanosine containing compound metabolic processGO:19010682440.011
glycoprotein metabolic processGO:00091001100.011
actin filament based movementGO:0030048170.011
cell divisionGO:00513011680.011
lipid modificationGO:0030258840.011
positive regulation of organelle organizationGO:00106381950.011
neuroblast proliferationGO:000740540.011
nucleotide biosynthetic processGO:00091651090.011
histone modificationGO:00165702510.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
positive regulation of plasminogen activationGO:001075630.011
response to bacteriumGO:00096171440.011
vitamin k biosynthetic processGO:004237120.011
nucleoside phosphate biosynthetic processGO:19012931090.011
neurotransmitter secretionGO:000726940.011
response to oxidative stressGO:00069791210.011
Human
positive regulation of cytokine productionGO:00018191670.011
sensory perception of painGO:001923340.011
specification of organ identityGO:001009230.011
regulation of cytokine productionGO:00018172320.011
spinal cord developmentGO:002151040.011
atp catabolic processGO:00062001570.011
guanosine containing compound catabolic processGO:19010692390.011
regulation of viral processGO:00507921030.011
regulation of cell adhesionGO:00301551660.010
Human
divalent inorganic cation transportGO:00725111580.010
cell cycle phase transitionGO:00447701730.010
nervous system developmentGO:00073992930.010
regulation of cytoplasmic transportGO:19036491490.010
calcium ion homeostasisGO:00550741220.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
positive regulation of apoptotic processGO:00430652460.010
cellular response to lipidGO:00713961270.010
cellular response to organonitrogen compoundGO:00714171240.010
positive regulation of proteolysisGO:00458621420.010
embryonic placenta developmentGO:000189210.010
myoblast fusionGO:000752010.010
negative regulation of transferase activityGO:00513481240.010
cerebellum developmentGO:002154920.010
regulation of protein secretionGO:0050708860.010
response to oxygen levelsGO:00704821000.010
protein localization to nucleusGO:00345041360.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
Human
regulation of cell developmentGO:00602841610.010
regulation of immune effector processGO:0002697910.010
cellular response to external stimulusGO:00714961110.010
positive regulation of nucleotide catabolic processGO:00308131850.010
positive regulation of neural precursor cell proliferationGO:200017920.010
organ morphogenesisGO:00098871470.010
Human
positive regulation of gtp catabolic processGO:00331261660.010
intrinsic apoptotic signaling pathwayGO:00971931270.010

F12 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.118
inherited metabolic disorderDOID:6552420.118
eye and adnexa diseaseDOID:14921500.018
nervous system diseaseDOID:8634310.018
Human
sensory system diseaseDOID:00501552030.018
Human
eye diseaseDOID:56141490.018
musculoskeletal system diseaseDOID:172230.017
organ system cancerDOID:00506861640.015
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
amino acid metabolic disorderDOID:9252500.015
hematopoietic system diseaseDOID:741000.015
Human
immune system diseaseDOID:29141550.015
Human
central nervous system diseaseDOID:3311860.015
Human
retinal diseaseDOID:56791180.013
connective tissue diseaseDOID:651090.012
bone diseaseDOID:0080001880.012
retinal degenerationDOID:8466890.010
integumentary system diseaseDOID:16430.006
skin diseaseDOID:37330.004