Homo sapiens

332 known processes

CLU

clusterin

(Aliases: CLI,SGP2,APOJ,MGC24903,SGP-2,KUB1,SP-40,TRPM-2,TRPM2)

CLU biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.416
cellular amine metabolic processGO:0044106410.342
regulation of cellular amine metabolic processGO:0033238110.286
positive regulation of immune system processGO:00026842830.284
regulation of cellular amino acid metabolic processGO:000652160.276
positive regulation of cell deathGO:00109422630.272
cellular component morphogenesisGO:00329893140.253
immune responseGO:00069553070.244
positive regulation of developmental processGO:00510943140.237
growthGO:00400072020.230
response to woundingGO:00096111680.229
positive regulation of programmed cell deathGO:00430682490.208
positive regulation of apoptotic signaling pathwayGO:2001235700.203
regulation of cell differentiationGO:00455953930.183
positive regulation of apoptotic processGO:00430652460.177
regulation of cell motilityGO:20001452990.172
response to oxygen containing compoundGO:19017003690.166
activation of immune responseGO:00022531140.164
cellular amino acid metabolic processGO:00065201160.163
protein processingGO:00164852260.163
apoptotic signaling pathwayGO:00971902680.157
protein maturationGO:00516042330.156
regulation of cellular component movementGO:00512703340.153
protein homooligomerizationGO:00512601000.152
positive regulation of immune responseGO:00507781590.152
regenerationGO:003109940.151
regulation of cell migrationGO:00303342890.151
cellular lipid metabolic processGO:00442553030.150
negative regulation of apoptotic processGO:00430663160.147
response to organic cyclic compoundGO:00140702040.146
amine metabolic processGO:0009308440.145
positive regulation of cellular component organizationGO:00511303760.141
response to abiotic stimulusGO:00096283360.141
regulation of cellular component biogenesisGO:00440872810.135
chemical homeostasisGO:00488783060.123
cell morphogenesisGO:00009022960.121
defense responseGO:00069523150.111
negative regulation of cell deathGO:00605483450.108
regulation of proteolysisGO:00301622930.106
regulation of peptidase activityGO:00525471800.106
protein oligomerizationGO:00512591730.103
cell adhesionGO:00071553250.103
regulation of immune responseGO:00507762010.103
mitotic cell cycle processGO:19030472860.100
system processGO:00030083490.099
ion homeostasisGO:00508012300.098
cellular response to oxygen containing compoundGO:19017012760.098
regulation of growthGO:00400081650.096
response to external biotic stimulusGO:00432072610.096
inorganic cation transmembrane transportGO:00986621940.094
metal ion transportGO:00300012720.093
regulation of apoptotic signaling pathwayGO:20012331750.091
positive regulation of cellular amine metabolic processGO:003324070.090
biological adhesionGO:00226103310.090
regulation of cellular ketone metabolic processGO:0010565500.090
post embryonic developmentGO:000979120.089
lipid metabolic processGO:00066293810.089
immune effector processGO:00022521590.089
regulation of endopeptidase activityGO:00525481700.088
nervous system developmentGO:00073992930.087
negative regulation of cell proliferationGO:00082852280.087
cation transportGO:00068123310.084
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.084
positive regulation of peptidase activityGO:0010952880.083
regulation of defense responseGO:00313471540.083
cell projection organizationGO:00300302520.082
negative regulation of programmed cell deathGO:00430693210.081
cellular response to endogenous stimulusGO:00714953360.081
negative regulation of cellular protein metabolic processGO:00322693530.079
innate immune responseGO:00450871780.078
multicellular organismal agingGO:001025930.077
cell developmentGO:00484683280.077
negative regulation of protein metabolic processGO:00512483910.075
response to drugGO:0042493810.075
epithelium developmentGO:00604292270.075
positive regulation of hydrolase activityGO:00513453310.074
anatomical structure formation involved in morphogenesisGO:00486462840.074
positive regulation of transportGO:00510503360.074
single organism cell adhesionGO:00986021790.073
cell activationGO:00017752130.073
positive regulation of proteolysisGO:00458621420.071
cellular component disassemblyGO:0022411920.071
regulation of protein localizationGO:00328802960.071
protein localization to organelleGO:00333652800.070
regulation of establishment of protein localizationGO:00702012420.069
regulation of locomotionGO:00400123290.069
circulatory system developmentGO:00723592620.069
negative regulation of multicellular organismal processGO:00512413170.067
response to hormoneGO:00097251750.067
response to nitrogen compoundGO:19016981840.067
blood vessel developmentGO:00015681720.067
cellular homeostasisGO:00197251960.066
transmembrane transportGO:00550853990.066
response to other organismGO:00517072610.066
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.066
positive regulation of catabolic processGO:00098963100.065
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.064
regulation of protein kinase activityGO:00458592890.064
negative regulation of apoptotic signaling pathwayGO:2001234970.063
protein catabolic processGO:00301633250.062
regulation of branching involved in ureteric bud morphogenesisGO:009018930.062
chemotaxisGO:00069351570.062
single organism cellular localizationGO:19025803320.062
extrinsic apoptotic signaling pathwayGO:00971911190.061
regulation of anatomical structure morphogenesisGO:00226032860.060
apoptotic mitochondrial changesGO:0008637570.059
response to inorganic substanceGO:00100351270.059
positive regulation of cell differentiationGO:00455972110.059
signal transduction by phosphorylationGO:00230142970.058
enzyme linked receptor protein signaling pathwayGO:00071673030.058
cellular macromolecule catabolic processGO:00442653800.058
peptidyl tyrosine modificationGO:00182121700.058
positive regulation of phosphorylationGO:00423273940.058
response to reactive oxygen speciesGO:0000302610.058
mapk cascadeGO:00001652880.057
cellular ion homeostasisGO:00068731680.057
positive regulation of protein phosphorylationGO:00019343130.057
oxidation reduction processGO:00551143960.057
cation transmembrane transportGO:00986552380.057
locomotory behaviorGO:000762610.056
mitochondrion organizationGO:00070051560.056
inorganic ion transmembrane transportGO:00986602310.056
cardiovascular system developmentGO:00723582620.056
cation homeostasisGO:00550801890.055
response to extracellular stimulusGO:0009991850.054
regulation of cell growthGO:00015581350.053
positive regulation of cellular component biogenesisGO:00440891580.052
cellular response to external stimulusGO:00714961110.052
response to lipidGO:00339932060.052
nucleocytoplasmic transportGO:00069131760.051
epithelial cell migrationGO:00106311190.051
cytokine productionGO:00018162470.051
positive regulation of transferase activityGO:00513472270.051
vesicle mediated transportGO:00161923710.051
positive regulation of cellular amino acid metabolic processGO:004576430.050
regulation of transferase activityGO:00513383550.050
positive regulation of cellular catabolic processGO:00313312840.048
lung alveolus developmentGO:004828640.048
purine ribonucleoside triphosphate metabolic processGO:00092054110.047
cell growthGO:00160491600.046
mitochondrial transportGO:0006839600.046
positive regulation of organelle organizationGO:00106381950.046
multicellular organismal homeostasisGO:0048871670.045
myeloid cell differentiationGO:00300991170.045
cellular response to extracellular stimulusGO:0031668720.045
response to hypoxiaGO:0001666960.044
negative regulation of immune system processGO:00026831360.044
zymogen activationGO:0031638700.044
regulation of peptidyl tyrosine phosphorylationGO:00507301080.043
positive regulation of cell motilityGO:20001471770.043
segmentationGO:003528240.043
tissue regenerationGO:004224630.043
actin filament based processGO:00300292240.043
regulation of mapk cascadeGO:00434082620.042
regulation of multi organism processGO:00439001570.042
negative regulation of developmental processGO:00510932470.041
negative regulation of locomotionGO:00400131180.041
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.041
regulation of cysteine type endopeptidase activityGO:20001161270.040
epithelial cell differentiationGO:00308551410.040
negative regulation of trophoblast cell migrationGO:190116430.040
lymphocyte activationGO:00466491330.040
positive regulation of cell proliferationGO:00082843010.040
response to organonitrogen compoundGO:00102431560.040
negative regulation of hydrolase activityGO:00513461820.040
central nervous system developmentGO:00074171230.039
endothelial cell migrationGO:0043542860.039
defense response to other organismGO:00985421290.039
negative regulation of protein phosphorylationGO:00019331400.039
cellular metal ion homeostasisGO:00068751460.038
cellular potassium ion transportGO:0071804600.038
steroid metabolic processGO:0008202940.038
taxisGO:00423301570.038
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.038
negative regulation of cell growthGO:0030308830.037
regulation of mitochondrion organizationGO:0010821540.037
response to biotic stimulusGO:00096072760.037
protein modification by small protein conjugationGO:00324463420.037
purine ribonucleoside metabolic processGO:00461284370.037
monovalent inorganic cation transportGO:00156721280.037
cellular cation homeostasisGO:00300031630.037
negative regulation of phosphorus metabolic processGO:00105632670.037
negative regulation of protein maturationGO:19033181420.036
regulation of protein maturationGO:19033171500.036
cell cycle phase transitionGO:00447701730.036
positive regulation of cysteine type endopeptidase activityGO:2001056790.036
posttranscriptional regulation of gene expressionGO:00106082130.036
hemopoiesisGO:00300971800.036
negative regulation of phosphate metabolic processGO:00459362670.036
cellular response to organic cyclic compoundGO:00714071270.035
head developmentGO:00603221080.035
negative regulation of catalytic activityGO:00430863350.035
memoryGO:000761330.035
regulation of dna metabolic processGO:00510521530.035
peptidyl tyrosine phosphorylationGO:00181081700.035
mitotic cell cycle phase transitionGO:00447721620.035
patterning of blood vesselsGO:000156920.035
regulation of cell developmentGO:00602841610.035
response to decreased oxygen levelsGO:0036293960.035
peripheral nervous system developmentGO:000742220.034
response to oxygen levelsGO:00704821000.034
leukocyte activationGO:00453211640.034
regulation of cytokine productionGO:00018172320.034
immune response regulating signaling pathwayGO:0002764970.034
monocarboxylic acid metabolic processGO:00327871850.034
cellular response to hydrogen peroxideGO:0070301370.034
regulation of protein processingGO:00706131500.033
single organism membrane organizationGO:00448022680.033
brain developmentGO:0007420970.033
gastrulationGO:0007369510.033
divalent inorganic cation homeostasisGO:00725071360.033
epithelial cell proliferationGO:00506731280.033
response to metal ionGO:0010038840.033
secretionGO:00469032540.032
regulation of response to external stimulusGO:00321012220.032
nuclear transportGO:00511691790.032
mitotic cell cycleGO:00002783260.032
blood vessel morphogenesisGO:00485141620.032
determination of adult lifespanGO:000834020.032
regulation of release of cytochrome c from mitochondriaGO:0090199290.031
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.031
calcium ion transportGO:00068161470.031
cellular response to starvationGO:0009267580.031
regulation of leukocyte activationGO:00026941150.030
cytoplasmic transportGO:00164823790.030
negative regulation of growthGO:0045926970.030
response to endoplasmic reticulum stressGO:0034976490.030
regulation of sequence specific dna binding transcription factor activityGO:00510902110.030
inflammatory responseGO:0006954790.030
metal ion homeostasisGO:00550651690.030
negative regulation of phosphorylationGO:00423261740.030
astrocyte differentiationGO:004870840.030
gland developmentGO:0048732480.030
neuromuscular junction developmentGO:000752830.029
negative regulation of cell motilityGO:20001461040.029
thymus developmentGO:004853830.029
intracellular protein transportGO:00068862700.029
secretion by cellGO:00329402260.029
ras protein signal transductionGO:0007265730.029
maintenance of locationGO:00512351120.029
nucleoside phosphate catabolic processGO:19012924120.029
positive regulation of cellular component movementGO:00512721810.028
cell morphogenesis involved in differentiationGO:00009041440.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
neuron projection regenerationGO:003110210.028
organic hydroxy compound metabolic processGO:19016151470.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.028
purine ribonucleotide catabolic processGO:00091544040.028
protein importGO:00170381300.028
angiogenesisGO:00015251470.028
tube developmentGO:00352951250.028
calcium ion homeostasisGO:00550741220.028
negative regulation of cellular amine metabolic processGO:003323930.028
regulation of protein oligomerizationGO:0032459260.028
cellular chemical homeostasisGO:00550821800.028
regulation of lymphocyte activationGO:00512491030.027
embryonic morphogenesisGO:0048598850.027
intrinsic apoptotic signaling pathwayGO:00971931270.027
positive regulation of endopeptidase activityGO:0010950840.027
ossificationGO:00015031210.027
circulatory system processGO:00030131130.027
adult locomotory behaviorGO:000834410.027
response to radiationGO:00093141510.027
positive regulation of cell migrationGO:00303351720.027
release of cytochrome c from mitochondriaGO:0001836350.027
response to steroid hormoneGO:0048545800.027
positive regulation of protein transportGO:00512221350.027
embryo developmentGO:00097901230.026
negative regulation of protein modification processGO:00314002000.026
single organism carbohydrate metabolic processGO:00447231930.026
regulation of kinase activityGO:00435493140.026
cellular response to nutrient levelsGO:0031669690.026
developmental growthGO:0048589480.026
neurological system processGO:00508771630.026
positive regulation of protein kinase activityGO:00458601900.026
negative regulation of cellular component movementGO:00512711060.025
sleepGO:003043120.025
immune response activating signal transductionGO:0002757900.025
response to axon injuryGO:004867810.025
symbiosis encompassing mutualism through parasitismGO:00444031560.025
cellular response to organonitrogen compoundGO:00714171240.025
cellular calcium ion homeostasisGO:00068741170.025
positive regulation of cytokine productionGO:00018191670.025
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.025
cellular response to oxidative stressGO:0034599850.024
regulation of bindingGO:00510981110.024
cellular response to oxygen levelsGO:0071453550.024
defense response to bacteriumGO:0042742630.024
endocytosisGO:00068971590.024
generation of neuronsGO:00486991520.024
cell part morphogenesisGO:00329901370.024
cellular macromolecular complex assemblyGO:00346223240.024
protein activation cascadeGO:0072376220.024
fatty acid metabolic processGO:00066311150.024
developmental programmed cell deathGO:001062330.024
regulation of cell activationGO:00508651250.024
regulation of membrane potentialGO:0042391950.024
phagocytosis recognitionGO:000691030.024
potassium ion transmembrane transportGO:0071805600.024
nucleoside triphosphate catabolic processGO:00091433940.024
negative regulation of peptidase activityGO:0010466910.023
regulation of vesicle mediated transportGO:00606271300.023
response to oxidative stressGO:00069791210.023
immune system developmentGO:00025201950.023
cellular divalent inorganic cation homeostasisGO:00725031280.023
response to starvationGO:0042594590.023
cellular response to growth factor stimulusGO:00713631970.023
negative regulation of immune responseGO:0050777400.023
response to cytokineGO:00340972320.023
protein ubiquitinationGO:00165673140.023
regulation of protein transportGO:00512232130.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
negative regulation of proteolysisGO:00458611320.023
ion transmembrane transportGO:00342203380.023
lipid biosynthetic processGO:00086101770.023
response to light stimulusGO:0009416870.023
associative learningGO:000830610.023
single organismal cell cell adhesionGO:00163371480.022
vasculature developmentGO:00019441810.022
regulation of innate immune responseGO:0045088970.022
glial cell migrationGO:000834740.022
cerebral cortex radially oriented cell migrationGO:002179910.022
muscle cell fate commitmentGO:004269340.022
spermatid differentiationGO:004851540.022
circadian behaviorGO:004851220.022
organic acid biosynthetic processGO:0016053970.022
cellular response to dna damage stimulusGO:00069743790.022
regulation of membrane permeabilityGO:0090559250.022
regulation of cell adhesionGO:00301551660.022
kidney developmentGO:0001822530.022
brain morphogenesisGO:004885410.022
regulation of epithelial cell proliferationGO:00506781130.022
regulation of response to woundingGO:19030341010.022
alcohol metabolic processGO:00060661140.022
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.022
regulation of homeostatic processGO:00328441210.022
humoral immune responseGO:0006959490.021
cerebral cortex cell migrationGO:002179530.021
negative regulation of cell cycleGO:00457861930.021
atp metabolic processGO:00460341760.021
cell substrate adhesionGO:00315891320.021
response to bacteriumGO:00096171440.021
sensory organ developmentGO:0007423520.021
anatomical structure homeostasisGO:00602491000.021
tissue homeostasisGO:0001894630.021
establishment of protein localization to organelleGO:00725941720.021
cell projection morphogenesisGO:00488581290.021
mitochondrial membrane organizationGO:0007006400.021
positive regulation of pathway restricted smad protein phosphorylationGO:0010862220.021
cell junction organizationGO:0034330790.021
regulation of secretion by cellGO:19035301770.021
response to nutrient levelsGO:0031667810.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
establishment of protein localization to membraneGO:00901501210.021
extracellular structure organizationGO:0043062410.020
regulation of protein secretionGO:0050708860.020
cellular protein complex assemblyGO:00436231880.020
regulation of neural precursor cell proliferationGO:200017740.020
regulation of intracellular transportGO:00323861950.020
carboxylic acid biosynthetic processGO:0046394970.020
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100410.020
positive regulation of mapk cascadeGO:00434101900.020
viral processGO:00160321460.020
peptidyl serine modificationGO:00182091060.020
carbohydrate derivative biosynthetic processGO:19011372070.020
myeloid leukocyte differentiationGO:0002573600.020
positive regulation of ras gtpase activityGO:00323201170.020
positive regulation of kinase activityGO:00336742040.020
sequestering of metal ionGO:0051238240.020
complement activationGO:0006956190.019
wound healingGO:00420601150.019
digestive tract developmentGO:0048565750.019
extracellular matrix organizationGO:0030198410.019
reactive oxygen species metabolic processGO:0072593750.019
somitogenesisGO:000175620.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
hindbrain developmentGO:003090230.019
t cell activationGO:0042110990.019
positive regulation of epithelial cell proliferationGO:0050679650.019
leukocyte differentiationGO:0002521980.019
ameboidal type cell migrationGO:00016671350.019
small gtpase mediated signal transductionGO:0007264780.019
protein import into nucleusGO:00066061040.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
negative regulation of cell cycle processGO:00109481210.019
regulation of lymphocyte proliferationGO:0050670640.019
negative regulation of cellular component organizationGO:00511292350.019
regulation of t cell activationGO:0050863770.019
neurogenesisGO:00220081690.019
regulation of protein complex assemblyGO:00432541470.019
cell junction assemblyGO:0034329670.019
purine containing compound catabolic processGO:00725234110.019
positive regulation of dna metabolic processGO:0051054730.019
response to alcoholGO:0097305640.019
response to hydrogen peroxideGO:0042542400.018
reproductive processGO:00224141060.018
rhythmic behaviorGO:000762220.018
epithelium migrationGO:00901321190.018
regulation of actin filament based processGO:00329701410.018
cellular amide metabolic processGO:0043603690.018
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.018
cellular response to nitrogen compoundGO:19016991440.018
cellular modified amino acid metabolic processGO:0006575640.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
detection of chemical stimulusGO:0009593550.018
translationGO:00064121320.018
regulation of cell cycleGO:00517263930.018
negative regulation of cell migrationGO:00303361020.018
divalent inorganic cation transportGO:00725111580.018
positive regulation of intracellular transportGO:00323881040.018
regulation of cellular response to stressGO:00801352440.018
tissue morphogenesisGO:0048729960.018
negative regulation of cell differentiationGO:00455961710.018
potassium ion transportGO:0006813620.018
lens development in camera type eyeGO:000208820.018
nucleus localizationGO:005164710.018
cell type specific apoptotic processGO:00972851250.018
pathway restricted smad protein phosphorylationGO:0060389380.018
response to mechanical stimulusGO:0009612510.018
cell matrix adhesionGO:0007160850.017
mitral valve developmentGO:000317430.017
blastoderm segmentationGO:000735020.017
mammary gland morphogenesisGO:006044320.017
response to fungusGO:000962040.017
protein targetingGO:00066051870.017
protein localization to membraneGO:00726571600.017
cell projection assemblyGO:00300311260.017
regulation of angiogenesisGO:0045765920.017
rho protein signal transductionGO:0007266260.017
limbic system developmentGO:002176130.017
dna replicationGO:00062601160.017
cellular response to hypoxiaGO:0071456510.017
protein targeting to nucleusGO:00447441040.017
cellular response to reactive oxygen speciesGO:0034614500.017
positive regulation of lymphocyte activationGO:0051251730.017
cell substrate junction assemblyGO:0007044350.017
muscle tissue developmentGO:0060537620.017
single organism reproductive processGO:0044702980.017
atrial septum primum morphogenesisGO:000328910.017
positive regulation of response to external stimulusGO:0032103880.016
regulation of cell morphogenesisGO:00226041530.016
regulation of ras gtpase activityGO:00323181280.016
cellular response to glucocorticoid stimulusGO:007138540.016
negative regulation of cellular catabolic processGO:0031330830.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
heart contractionGO:0060047620.016
blood circulationGO:00080151130.016
positive regulation of mitochondrion organizationGO:0010822300.016
regulation of hormone levelsGO:00108171250.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
response to organophosphorusGO:0046683410.016
negative regulation of multi organism processGO:0043901920.016
regulation of lipid metabolic processGO:0019216960.016
interspecies interaction between organismsGO:00444191560.016
neuron developmentGO:00486661130.016
single organism nuclear importGO:19025931040.016
neural tube patterningGO:002153220.016
chondrocyte developmentGO:000206310.016
regulation of cellular protein catabolic processGO:1903362960.016
striated muscle tissue developmentGO:0014706590.016
positive regulation of secretionGO:00510471160.016
negative regulation of protein processingGO:00109551420.016
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.016
organophosphate catabolic processGO:00464344300.016
protein secretionGO:0009306980.016
regulation of mitochondrial membrane permeabilityGO:0046902250.015
cell chemotaxisGO:00603261120.015
positive regulation of mesonephros developmentGO:006121320.015

CLU disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:12871060.206
disease of metabolismDOID:00146672950.116
central nervous system diseaseDOID:3311860.101
nervous system diseaseDOID:8634310.101
eye diseaseDOID:56141490.066
sensory system diseaseDOID:00501552030.066
eye and adnexa diseaseDOID:14921500.066
neurodegenerative diseaseDOID:12891020.049
muscular diseaseDOID:00800001140.037
muscle tissue diseaseDOID:661130.037
musculoskeletal system diseaseDOID:172230.037
disease of mental healthDOID:150700.036
inherited metabolic disorderDOID:6552420.033
myopathyDOID:4231040.032
heart diseaseDOID:114680.030
cardiomyopathyDOID:0050700500.027
immune system diseaseDOID:29141550.026
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.025
retinal diseaseDOID:56791180.022
retinal degenerationDOID:8466890.022
brain diseaseDOID:936730.022
organ system cancerDOID:00506861640.021
acquired metabolic diseaseDOID:0060158580.019
hematopoietic system diseaseDOID:741000.019
gastrointestinal system cancerDOID:3119520.016