Homo sapiens

37 known processes

INPPL1

inositol polyphosphate phosphatase-like 1

(Aliases: SHIP2)

INPPL1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin filament organizationGO:00070151280.657
actin filament based processGO:00300292240.504
cell cell junction organizationGO:0045216690.359
regulation of cellular ketone metabolic processGO:0010565500.274
actin cytoskeleton organizationGO:00300362070.246
enzyme linked receptor protein signaling pathwayGO:00071673030.236
Rat
cellular response to nitrogen compoundGO:19016991440.231
Rat
regulation of cellular component biogenesisGO:00440872810.222
lipid metabolic processGO:00066293810.193
Mouse
cellular ketone metabolic processGO:0042180800.176
cellular amine metabolic processGO:0044106410.167
positive regulation of organelle organizationGO:00106381950.165
membrane organizationGO:00610242920.164
response to organic cyclic compoundGO:00140702040.156
regulation of protein localizationGO:00328802960.144
protein localization to membraneGO:00726571600.142
regulation of cellular amino acid metabolic processGO:000652160.141
regulation of actin filament based processGO:00329701410.133
cell junction assemblyGO:0034329670.132
single organism cellular localizationGO:19025803320.125
response to oxygen containing compoundGO:19017003690.117
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.112
Rat
single organism carbohydrate metabolic processGO:00447231930.104
Mouse
positive regulation of mapk cascadeGO:00434101900.104
positive regulation of neural precursor cell proliferationGO:200017920.101
cell projection organizationGO:00300302520.100
Mouse Rat
positive regulation of cellular component biogenesisGO:00440891580.097
cellular response to endogenous stimulusGO:00714953360.095
Rat
cellular amino acid metabolic processGO:00065201160.095
ras protein signal transductionGO:0007265730.093
negative regulation of catalytic activityGO:00430863350.092
Rat
adherens junction assemblyGO:0034333340.089
oxidation reduction processGO:00551143960.088
endomembrane system organizationGO:00102561960.088
regulation of cellular amine metabolic processGO:0033238110.087
regulation of actin filament bundle assemblyGO:0032231360.085
biological adhesionGO:00226103310.083
post embryonic developmentGO:000979120.082
Mouse Worm
cellular polysaccharide metabolic processGO:0044264270.081
negative regulation of developmental processGO:00510932470.078
Rat
cell junction organizationGO:0034330790.078
nucleoside catabolic processGO:00091644080.076
negative regulation of cellular protein metabolic processGO:00322693530.075
Rat
regulation of mapk cascadeGO:00434082620.075
Rat
negative regulation of phosphorus metabolic processGO:00105632670.073
Rat
mitotic cell cycleGO:00002783260.073
potassium ion transportGO:0006813620.072
protein modification by small protein conjugationGO:00324463420.070
regulation of protein localization to plasma membraneGO:1903076400.070
metal ion transportGO:00300012720.070
cell developmentGO:00484683280.070
Rat
stress fiber assemblyGO:0043149400.069
regulation of cell projection organizationGO:00313441070.068
Rat
cellular response to peptide hormone stimulusGO:0071375560.066
Rat
amine metabolic processGO:0009308440.066
cellular response to peptideGO:1901653590.065
Rat
actin filament bundle organizationGO:0061572540.063
protein localization to plasma membraneGO:0072659930.062
positive regulation of transportGO:00510503360.061
negative regulation of cellular component organizationGO:00511292350.060
Rat
purine ribonucleoside metabolic processGO:00461284370.058
cellular response to oxygen containing compoundGO:19017012760.058
Rat
organ morphogenesisGO:00098871470.058
determination of adult lifespanGO:000834020.057
lipid biosynthetic processGO:00086101770.056
Mouse
adherens junction organizationGO:0034332360.056
cell adhesionGO:00071553250.055
actin filament bundle assemblyGO:0051017540.054
regulation of cytoskeleton organizationGO:00514931770.054
cell matrix adhesionGO:0007160850.053
establishment of protein localization to plasma membraneGO:0090002680.050
positive regulation of actin filament bundle assemblyGO:0032233250.049
regulation of kinase activityGO:00435493140.048
Rat
cellular response to organonitrogen compoundGO:00714171240.048
Rat
response to organonitrogen compoundGO:00102431560.047
Mouse Rat
epithelium developmentGO:00604292270.047
cellular carbohydrate metabolic processGO:0044262840.047
ribonucleoside triphosphate catabolic processGO:00092033910.047
female gamete generationGO:000729220.046
peptidyl tyrosine modificationGO:00182121700.046
intracellular protein transportGO:00068862700.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
positive regulation of cytoskeleton organizationGO:0051495830.045
signal transduction by phosphorylationGO:00230142970.044
Rat
negative regulation of transferase activityGO:00513481240.043
Rat
establishment of protein localization to membraneGO:00901501210.043
glycogen biosynthetic processGO:0005978160.043
regulation of cell developmentGO:00602841610.042
Rat
nervous system developmentGO:00073992930.042
Rat
ribonucleoside triphosphate metabolic processGO:00091994120.042
regulation of mitotic cell cycleGO:00073461890.041
regulation of cell cycleGO:00517263930.041
regulation of cellular component movementGO:00512703340.041
cellular protein complex assemblyGO:00436231880.039
monovalent inorganic cation transportGO:00156721280.039
response to nitrogen compoundGO:19016981840.038
Mouse Rat
negative regulation of phosphate metabolic processGO:00459362670.038
Rat
regulation of cell morphogenesisGO:00226041530.038
neural tube formationGO:000184130.037
monosaccharide metabolic processGO:0005996740.037
Mouse
microtubule based processGO:00070172100.037
nucleoside triphosphate metabolic processGO:00091414220.037
neurogenesisGO:00220081690.037
Rat
cell substrate junction assemblyGO:0007044350.037
nucleoside triphosphate catabolic processGO:00091433940.037
sensory perceptionGO:00076001030.037
regulation of actin cytoskeleton organizationGO:00329561160.036
positive regulation of cellular component organizationGO:00511303760.036
positive regulation of erk1 and erk2 cascadeGO:0070374750.036
actomyosin structure organizationGO:0031032590.034
regulation of immune responseGO:00507762010.034
response to growth factorGO:00708482050.034
negative regulation of cell differentiationGO:00455961710.034
Rat
regulation of peptidyl tyrosine phosphorylationGO:00507301080.034
regulation of lipid metabolic processGO:0019216960.034
regulation of protein catabolic processGO:00421761550.033
epithelial cell differentiationGO:00308551410.033
immune responseGO:00069553070.033
regulation of neural precursor cell proliferationGO:200017740.033
regulation of transferase activityGO:00513383550.033
Rat
negative regulation of cell cycleGO:00457861930.033
regulation of polysaccharide biosynthetic processGO:0032885200.033
cellular macromolecular complex assemblyGO:00346223240.032
regenerationGO:003109940.032
neurotrophin trk receptor signaling pathwayGO:004801140.032
regulation of proteolysisGO:00301622930.032
epithelial cell developmentGO:0002064340.031
small gtpase mediated signal transductionGO:0007264780.031
regulation of cell cycle processGO:00105642660.031
cell projection morphogenesisGO:00488581290.030
spermatid differentiationGO:004851540.030
retinal ganglion cell axon guidanceGO:003129020.030
regulation of stress fiber assemblyGO:0051492320.030
anatomical structure formation involved in morphogenesisGO:00486462840.029
cellular response to hormone stimulusGO:00328701250.029
Rat
response to peptide hormoneGO:0043434610.029
Mouse Rat
negative regulation of programmed cell deathGO:00430693210.028
negative regulation of cellular amine metabolic processGO:003323930.028
hexose metabolic processGO:0019318550.028
Mouse
epithelial cell migrationGO:00106311190.028
spermatid developmentGO:000728640.027
convergent extension involved in gastrulationGO:006002710.027
convergent extensionGO:006002610.027
cellular component morphogenesisGO:00329893140.027
head developmentGO:00603221080.027
Rat
tissue migrationGO:00901301190.027
peptidyl tyrosine phosphorylationGO:00181081700.027
hindbrain developmentGO:003090230.026
negative regulation of phosphorylationGO:00423261740.026
Rat
multicellular organismal agingGO:001025930.026
microtubule cytoskeleton organizationGO:00002261760.026
mitotic cell cycle processGO:19030472860.026
organelle localizationGO:0051640840.026
response to abiotic stimulusGO:00096283360.026
regulation of glucose importGO:0046324210.026
regulation of cell cycle phase transitionGO:19019871260.026
posttranscriptional regulation of gene expressionGO:00106082130.026
regulation of lipid biosynthetic processGO:0046890470.025
morphogenesis of a polarized epitheliumGO:000173830.025
response to toxic substanceGO:0009636370.025
negative regulation of protein metabolic processGO:00512483910.024
Rat
neuron projection developmentGO:00311751060.024
Rat
positive regulation of catabolic processGO:00098963100.024
system processGO:00030083490.024
glycosyl compound catabolic processGO:19016584130.024
negative regulation of cell deathGO:00605483450.024
regulation of protein kinase activityGO:00458592890.024
Rat
positive regulation of phosphorylationGO:00423273940.024
cdc42 protein signal transductionGO:003248840.024
positive regulation of developmental processGO:00510943140.024
ameboidal type cell migrationGO:00016671350.024
glucan metabolic processGO:0044042220.024
rho protein signal transductionGO:0007266260.024
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
protein dephosphorylationGO:0006470810.023
endothelial cell migrationGO:0043542860.023
negative regulation of protein phosphorylationGO:00019331400.023
Rat
regulation of protein polymerizationGO:0032271630.023
regulation of short term neuronal synaptic plasticityGO:004817210.023
polysaccharide biosynthetic processGO:0000271270.023
i kappab kinase nf kappab signalingGO:00072491660.022
regulation of cell migrationGO:00303342890.022
regulation of establishment of protein localizationGO:00702012420.022
interleukin 2 secretionGO:007097030.022
protein ubiquitinationGO:00165673140.022
positive regulation of cell proliferationGO:00082843010.022
cation transportGO:00068123310.022
replacement ossificationGO:003607510.022
cell morphogenesis involved in differentiationGO:00009041440.022
neuromuscular junction developmentGO:000752830.022
positive regulation of endothelial cell migrationGO:0010595390.022
ossificationGO:00015031210.022
purine containing compound catabolic processGO:00725234110.022
morphogenesis of embryonic epitheliumGO:001633140.021
golgi vesicle transportGO:0048193800.021
salivary gland morphogenesisGO:000743540.021
guanosine containing compound catabolic processGO:19010692390.021
blood vessel developmentGO:00015681720.021
protein autophosphorylationGO:00467771230.021
establishment of organelle localizationGO:0051656590.021
protein catabolic processGO:00301633250.021
cellular macromolecule catabolic processGO:00442653800.021
cell substrate adhesionGO:00315891320.021
muscle structure developmentGO:0061061980.021
negative regulation of cell cycle processGO:00109481210.020
positive regulation of lipid biosynthetic processGO:0046889220.020
response to hormoneGO:00097251750.020
Mouse Rat
regulation of anatomical structure morphogenesisGO:00226032860.020
purine ribonucleotide catabolic processGO:00091544040.020
energy reserve metabolic processGO:0006112220.020
neural tube closureGO:000184330.020
protein polymerizationGO:0051258710.020
negative regulation of intracellular signal transductionGO:19025321830.019
Rat
segmentationGO:003528240.019
mrna metabolic processGO:00160711750.019
dephosphorylationGO:00163112090.019
Rat
ion transmembrane transportGO:00342203380.019
positive regulation of protein tyrosine kinase activityGO:0061098240.019
modification dependent macromolecule catabolic processGO:00436322120.019
mitochondrion organizationGO:00070051560.019
ribonucleoside monophosphate metabolic processGO:00091611870.019
positive regulation of transferase activityGO:00513472270.019
response to peptideGO:1901652650.018
Mouse Rat
cytoplasmic transportGO:00164823790.018
cellular polysaccharide biosynthetic processGO:0033692210.018
positive regulation of carbohydrate metabolic processGO:0045913210.018
motor neuron axon guidanceGO:000804520.018
ribonucleoside catabolic processGO:00424544060.018
covalent chromatin modificationGO:00165692540.018
cellular glucan metabolic processGO:0006073220.018
brain developmentGO:0007420970.018
Rat
regulation of locomotionGO:00400123290.018
positive regulation of protein phosphorylationGO:00019343130.018
memoryGO:000761330.018
cell migration involved in gastrulationGO:004207410.018
lung alveolus developmentGO:004828640.017
regulation of stress activated protein kinase signaling cascadeGO:0070302850.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
epithelial tube branching involved in lung morphogenesisGO:006044140.017
mapk cascadeGO:00001652880.017
Rat
sensory perception of soundGO:0007605370.017
cell projection assemblyGO:00300311260.017
Mouse
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
cerebral cortex radially oriented cell migrationGO:002179910.017
regulation of cellular carbohydrate metabolic processGO:0010675470.017
positive regulation of stress fiber assemblyGO:0051496220.017
positive regulation of lipid metabolic processGO:0045834500.017
muscle organ developmentGO:0007517560.017
nucleus localizationGO:005164710.017
guanosine containing compound metabolic processGO:19010682440.017
maintenance of cell polarityGO:003001120.017
actin filament based movementGO:0030048170.017
regulation of generation of precursor metabolites and energyGO:0043467270.017
regulation of cellular protein catabolic processGO:1903362960.017
negative regulation of mitotic cell cycle phase transitionGO:1901991850.016
neuron differentiationGO:00301821380.016
Rat
cellular response to growth factor stimulusGO:00713631970.016
oocyte developmentGO:004859910.016
single organism membrane organizationGO:00448022680.016
negative regulation of multicellular organismal processGO:00512413170.016
Rat
endosomal transportGO:00161971290.016
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
positive regulation of synaptic transmissionGO:005080640.016
negative regulation of cell migrationGO:00303361020.016
regulation of protein modification by small protein conjugation or removalGO:19033201070.016
regulation of cellular response to stressGO:00801352440.016
chromatin modificationGO:00165682980.016
phospholipid metabolic processGO:0006644990.016
Mouse
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.015
regulation of ras gtpase activityGO:00323181280.015
cell fate determinationGO:000170930.015
cerebral cortex cell migrationGO:002179530.015
positive regulation of gtp catabolic processGO:00331261660.015
energy derivation by oxidation of organic compoundsGO:0015980430.015
locomotory behaviorGO:000762610.015
purine nucleoside catabolic processGO:00061523980.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
fibroblast proliferationGO:0048144330.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
regulation of osteoblast differentiationGO:0045667380.015
sensory perception of mechanical stimulusGO:0050954370.015
regulation of cell differentiationGO:00455953930.015
Rat
jak stat cascadeGO:0007259460.015
cellular protein catabolic processGO:00442572610.015
osteoblast differentiationGO:0001649920.014
activation of immune responseGO:00022531140.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
positive regulation of cellular amine metabolic processGO:003324070.014
regulation of actin filament lengthGO:0030832560.014
central nervous system developmentGO:00074171230.014
Rat
heart developmentGO:0007507950.014
glycerophospholipid metabolic processGO:0006650840.014
Mouse
defense responseGO:00069523150.014
positive regulation of neurogenesisGO:0050769490.014
regulation of intracellular transportGO:00323861950.014
polysaccharide metabolic processGO:0005976330.014
positive regulation of cell cycle processGO:00900681060.014
regulation of vasodilationGO:004231240.014
carbohydrate transportGO:0008643370.014
positive regulation of cell projection organizationGO:0031346640.014
regulation of protein ubiquitinationGO:0031396950.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
secretionGO:00469032540.014
positive regulation of intracellular protein transportGO:0090316760.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
positive regulation of cell migrationGO:00303351720.014
regulation of response to external stimulusGO:00321012220.014
circulatory system processGO:00030131130.014
chromatin organizationGO:00063253510.014
glycogen metabolic processGO:0005977220.014
somitogenesisGO:000175620.014
nucleotide catabolic processGO:00091664080.013
anterior posterior axis specificationGO:000994820.013
embryonic epithelial tube formationGO:000183840.013
reproductive processGO:00224141060.013
negative regulation of cell motilityGO:20001461040.013
primary neural tube formationGO:001402030.013
cellular homeostasisGO:00197251960.013
protein localization to organelleGO:00333652800.013
response to cytokineGO:00340972320.013
plasma membrane organizationGO:00070091150.013
tissue regenerationGO:004224630.013
positive regulation of neuron projection developmentGO:0010976340.013
rhythmic behaviorGO:000762220.013
rna processingGO:00063962550.013
positive regulation of immune responseGO:00507781590.013
lymphocyte proliferationGO:0046651700.013
regulation of growthGO:00400081650.013
negative regulation of kinase activityGO:00336731060.013
Rat
brain morphogenesisGO:004885410.013
regulation of protein localization to nucleusGO:1900180850.013
erk1 and erk2 cascadeGO:00703711040.013
positive regulation of apoptotic processGO:00430652460.013
cell cycle g1 s phase transitionGO:0044843800.013
lung developmentGO:0030324200.013
metencephalon developmentGO:002203720.013
regulation of glycogen metabolic processGO:0070873150.013
negative regulation of organelle organizationGO:00106391260.012
response to hypoxiaGO:0001666960.012
negative regulation of protein serine threonine kinase activityGO:0071901570.012
Rat
cardiovascular system developmentGO:00723582620.012
taxisGO:00423301570.012
response to steroid hormoneGO:0048545800.012
vesicle mediated transportGO:00161923710.012
positive regulation of jak stat cascadeGO:0046427350.012
organic hydroxy compound metabolic processGO:19016151470.012
Rat
positive regulation of neuroblast proliferationGO:000205220.012
regulation of protein transportGO:00512232130.012
actin polymerization or depolymerizationGO:0008154560.012
regulation of cellular component sizeGO:0032535820.012
positive regulation of cell deathGO:00109422630.012
neurological system processGO:00508771630.012
glucose metabolic processGO:0006006450.012
Mouse
thymus developmentGO:004853830.012
cellular response to hepatocyte growth factor stimulusGO:003572960.012
positive regulation of rab gtpase activityGO:0032851390.012
regulation of dephosphorylationGO:0035303960.012
purine nucleotide catabolic processGO:00061954050.012
oogenesisGO:004847720.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
negative regulation of t cell receptor signaling pathwayGO:005086040.012
regulation of cell cycle g1 s phase transitionGO:1902806420.012
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
regulation of nervous system developmentGO:0051960880.012
Rat
respiratory system developmentGO:0060541220.012
cell cell signalingGO:00072671550.012
epithelial cell proliferationGO:00506731280.012
stress activated protein kinase signaling cascadeGO:0031098940.012
associative learningGO:000830610.011
cerebral cortex radial glia guided migrationGO:002180110.011
positive regulation of protein transportGO:00512221350.011
cell morphogenesisGO:00009022960.011
positive regulation of cell differentiationGO:00455972110.011
positive regulation of hydrolase activityGO:00513453310.011
organelle fissionGO:00482851490.011
positive regulation of histone deacetylase activityGO:190172730.011
generation of neuronsGO:00486991520.011
Rat
blastoderm segmentationGO:000735020.011
vascular process in circulatory systemGO:0003018290.011
cell chemotaxisGO:00603261120.011
positive regulation of map kinase activityGO:0043406800.011
regulation of neuronal synaptic plasticityGO:004816810.011
endocytosisGO:00068971590.011
axis elongationGO:000340140.011
regulation of natural killer cell proliferationGO:003281740.011
peripheral nervous system developmentGO:000742220.011
regulation of endopeptidase activityGO:00525481700.011
nitrogen compound transportGO:00717051910.011
nerve developmentGO:002167540.011
neural crest cell migrationGO:000175520.011
sensory perception of painGO:001923340.011
regulation of glucose metabolic processGO:0010906280.011
cell type specific apoptotic processGO:00972851250.011
neuron developmentGO:00486661130.011
Rat
short term memoryGO:000761410.011
transmembrane transportGO:00550853990.011
ubiquitin dependent protein catabolic processGO:00065112060.011
secretion by cellGO:00329402260.011
positive regulation of glucose transportGO:0010828170.011
maintenance of locationGO:00512351120.011
negative regulation of transportGO:00510511760.011
nuclear transportGO:00511691790.011
positive regulation of cell cycleGO:00457871400.011
glial cell migrationGO:000834740.011
regulation of reactive oxygen species biosynthetic processGO:190342630.010
neuroblast proliferationGO:000740540.010
regulation of protein processingGO:00706131500.010
regulation of protein complex assemblyGO:00432541470.010
angiogenesisGO:00015251470.010
actin mediated cell contractionGO:0070252120.010
single organismal cell cell adhesionGO:00163371480.010
single organism nuclear importGO:19025931040.010
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.010
response to antibioticGO:0046677150.010
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.010
cell substrate adherens junction assemblyGO:0007045300.010
central nervous system neuron axonogenesisGO:002195530.010
g1 s transition of mitotic cell cycleGO:0000082780.010
protein localization to cell junctionGO:190241430.010
cellular metal ion homeostasisGO:00068751460.010
negative regulation of phagocytosisGO:005076540.010
protein localization to nucleusGO:00345041360.010
regulation of secretionGO:00510461940.010
purine nucleoside triphosphate catabolic processGO:00091463920.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
mitotic nuclear divisionGO:00070671190.010
tripartite regional subdivisionGO:000735120.010

INPPL1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.046
central nervous system diseaseDOID:3311860.043
nervous system diseaseDOID:8634310.043
musculoskeletal system diseaseDOID:172230.029
inherited metabolic disorderDOID:6552420.029
muscular diseaseDOID:00800001140.027
myopathyDOID:4231040.022
muscle tissue diseaseDOID:661130.022
disease of mental healthDOID:150700.020
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
diabetes mellitusDOID:9351310.012
acquired metabolic diseaseDOID:0060158580.012
glucose metabolism diseaseDOID:4194320.012
carbohydrate metabolism diseaseDOID:0050013320.012
carbohydrate metabolic disorderDOID:2978550.011