Homo sapiens

0 known processes

PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

PFKFB4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.094
chemical homeostasisGO:00488783060.071
cellular amine metabolic processGO:0044106410.070
response to abiotic stimulusGO:00096283360.066
positive regulation of mapk cascadeGO:00434101900.066
anion transportGO:00068201610.064
positive regulation of phosphorylationGO:00423273940.063
regulation of cellular ketone metabolic processGO:0010565500.063
cation transportGO:00068123310.062
lipid metabolic processGO:00066293810.062
transmembrane transportGO:00550853990.061
positive regulation of cellular amino acid metabolic processGO:004576430.060
regulation of cellular amine metabolic processGO:0033238110.059
amine metabolic processGO:0009308440.057
ion homeostasisGO:00508012300.055
system processGO:00030083490.055
regulation of mapk cascadeGO:00434082620.054
post embryonic developmentGO:000979120.053
regulation of cellular amino acid metabolic processGO:000652160.052
cellular ketone metabolic processGO:0042180800.051
mapk cascadeGO:00001652880.048
positive regulation of cellular amine metabolic processGO:003324070.046
signal transduction by phosphorylationGO:00230142970.046
cellular lipid metabolic processGO:00442553030.046
negative regulation of catalytic activityGO:00430863350.046
organophosphate catabolic processGO:00464344300.045
ion transmembrane transportGO:00342203380.045
negative regulation of apoptotic processGO:00430663160.043
ribonucleoside triphosphate metabolic processGO:00091994120.043
lipid biosynthetic processGO:00086101770.043
determination of adult lifespanGO:000834020.042
regulation of transferase activityGO:00513383550.042
locomotory behaviorGO:000762610.042
female gamete generationGO:000729220.042
monocarboxylic acid metabolic processGO:00327871850.042
Human
purine nucleoside triphosphate metabolic processGO:00091444120.041
purine ribonucleotide catabolic processGO:00091544040.041
purine ribonucleoside metabolic processGO:00461284370.041
ribonucleoside catabolic processGO:00424544060.040
regulation of kinase activityGO:00435493140.040
positive regulation of transportGO:00510503360.040
small gtpase mediated signal transductionGO:0007264780.039
regulation of protein kinase activityGO:00458592890.039
carbohydrate metabolic processGO:00059752070.039
Human Yeast Rat
oxidation reduction processGO:00551143960.038
purine ribonucleoside triphosphate metabolic processGO:00092054110.038
positive regulation of protein phosphorylationGO:00019343130.038
ribonucleoside triphosphate catabolic processGO:00092033910.037
nucleoside phosphate catabolic processGO:19012924120.037
single organism carbohydrate metabolic processGO:00447231930.037
Human Yeast
negative regulation of programmed cell deathGO:00430693210.036
nitrogen compound transportGO:00717051910.036
segmentationGO:003528240.036
organic anion transportGO:00157111030.036
nucleoside triphosphate metabolic processGO:00091414220.035
cellular chemical homeostasisGO:00550821800.035
multicellular organismal agingGO:001025930.035
purine nucleoside triphosphate catabolic processGO:00091463920.035
nucleotide catabolic processGO:00091664080.035
regulation of ion transportGO:00432691890.034
oogenesisGO:004847720.034
defense responseGO:00069523150.034
purine containing compound catabolic processGO:00725234110.034
cytoplasmic transportGO:00164823790.034
neurological system processGO:00508771630.034
purine nucleoside catabolic processGO:00061523980.034
glycosyl compound catabolic processGO:19016584130.034
regulation of anatomical structure morphogenesisGO:00226032860.033
nucleoside catabolic processGO:00091644080.033
cellular response to dna damage stimulusGO:00069743790.033
positive regulation of cellular component organizationGO:00511303760.032
neuromuscular junction developmentGO:000752830.032
purine ribonucleoside catabolic processGO:00461303980.032
positive regulation of protein kinase activityGO:00458601900.032
negative regulation of cell deathGO:00605483450.032
positive regulation of transferase activityGO:00513472270.032
positive regulation of kinase activityGO:00336742040.032
cell adhesionGO:00071553250.031
cellular homeostasisGO:00197251960.031
negative regulation of multicellular organismal processGO:00512413170.031
ras protein signal transductionGO:0007265730.031
metal ion transportGO:00300012720.031
response to biotic stimulusGO:00096072760.031
negative regulation of phosphorus metabolic processGO:00105632670.031
cell developmentGO:00484683280.030
response to oxygen containing compoundGO:19017003690.030
chromatin modificationGO:00165682980.030
divalent metal ion transportGO:00708381520.029
ribonucleotide catabolic processGO:00092614050.029
negative regulation of cellular protein metabolic processGO:00322693530.029
regulation of protein localizationGO:00328802960.029
regulation of protein serine threonine kinase activityGO:00719001790.029
cation transmembrane transportGO:00986552380.028
response to decreased oxygen levelsGO:0036293960.028
regulation of purine nucleotide metabolic processGO:19005422640.028
cell morphogenesisGO:00009022960.028
single organism membrane organizationGO:00448022680.028
positive regulation of cell proliferationGO:00082843010.028
positive regulation of hydrolase activityGO:00513453310.028
epithelium developmentGO:00604292270.028
cation homeostasisGO:00550801890.028
regulation of response to external stimulusGO:00321012220.028
cellular macromolecule catabolic processGO:00442653800.028
negative regulation of phosphate metabolic processGO:00459362670.027
positive regulation of catabolic processGO:00098963100.027
negative regulation of protein metabolic processGO:00512483910.027
membrane organizationGO:00610242920.027
response to other organismGO:00517072610.027
response to external biotic stimulusGO:00432072610.027
regulation of cellular component movementGO:00512703340.027
organonitrogen compound biosynthetic processGO:19015662000.026
immune responseGO:00069553070.026
reactive oxygen species metabolic processGO:0072593750.026
anterior posterior axis specificationGO:000994820.026
maintenance of locationGO:00512351120.026
secretion by cellGO:00329402260.026
divalent inorganic cation transportGO:00725111580.026
memoryGO:000761330.026
nucleoside triphosphate catabolic processGO:00091433940.025
cellular component morphogenesisGO:00329893140.025
g protein coupled receptor signaling pathwayGO:00071862070.025
regulation of establishment of protein localizationGO:00702012420.025
regulation of cellular component biogenesisGO:00440872810.025
regulation of secretionGO:00510461940.025
cellular macromolecular complex assemblyGO:00346223240.025
purine nucleotide catabolic processGO:00061954050.025
actin filament based processGO:00300292240.025
vesicle mediated transportGO:00161923710.025
chromatin organizationGO:00063253510.025
dephosphorylationGO:00163112090.024
Human Yeast Rat
protein localization to organelleGO:00333652800.024
negative regulation of cellular component organizationGO:00511292350.024
microtubule based processGO:00070172100.024
regulation of cell differentiationGO:00455953930.024
response to hypoxiaGO:0001666960.024
metal ion homeostasisGO:00550651690.024
regulation of cellular response to stressGO:00801352440.023
cellular response to oxygen containing compoundGO:19017012760.023
single organism cellular localizationGO:19025803320.023
regenerationGO:003109940.023
regulation of cell cycleGO:00517263930.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
mitotic cell cycleGO:00002783260.023
regulation of reactive oxygen species metabolic processGO:2000377410.023
guanosine containing compound metabolic processGO:19010682440.023
cellular ion homeostasisGO:00068731680.023
protein catabolic processGO:00301633250.022
inorganic ion transmembrane transportGO:00986602310.022
nervous system developmentGO:00073992930.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
positive regulation of cell deathGO:00109422630.022
secretionGO:00469032540.022
blastoderm segmentationGO:000735020.022
biological adhesionGO:00226103310.022
apoptotic signaling pathwayGO:00971902680.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of proteolysisGO:00301622930.021
regulation of secretion by cellGO:19035301770.021
cell cell signalingGO:00072671550.021
rho protein signal transductionGO:0007266260.021
positive regulation of nucleotide metabolic processGO:00459812300.021
mitotic cell cycle processGO:19030472860.021
regulation of cell cycle processGO:00105642660.021
morphogenesis of embryonic epitheliumGO:001633140.021
neurotransmitter secretionGO:000726940.021
positive regulation of organelle organizationGO:00106381950.021
gtp metabolic processGO:00460392390.021
intracellular protein transportGO:00068862700.021
positive regulation of protein serine threonine kinase activityGO:00719021190.021
divalent inorganic cation homeostasisGO:00725071360.020
protein oligomerizationGO:00512591730.020
oocyte developmentGO:004859910.020
angiotensin activated signaling pathwayGO:003816640.020
small molecule biosynthetic processGO:00442831570.020
cell projection organizationGO:00300302520.020
regulation of cell motilityGO:20001452990.020
regulation of nucleotide metabolic processGO:00061402690.020
regulation of endopeptidase activityGO:00525481700.020
compound eye developmentGO:004874910.020
regulation of cell migrationGO:00303342890.020
cellular cation homeostasisGO:00300031630.020
growthGO:00400072020.020
response to oxygen levelsGO:00704821000.020
organophosphate biosynthetic processGO:00904071630.019
response to radiationGO:00093141510.019
carbohydrate derivative biosynthetic processGO:19011372070.019
microtubule cytoskeleton organizationGO:00002261760.019
positive regulation of cellular catabolic processGO:00313312840.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
guanosine containing compound catabolic processGO:19010692390.019
protein processingGO:00164852260.019
fatty acid metabolic processGO:00066311150.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
regulation of nucleotide catabolic processGO:00308112050.019
adult locomotory behaviorGO:000834410.019
negative regulation of transportGO:00510511760.019
organelle assemblyGO:00709251760.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
cellular protein catabolic processGO:00442572610.019
cofactor metabolic processGO:0051186870.019
regulation of protein transportGO:00512232130.019
oocyte differentiationGO:000999420.019
reactive nitrogen species metabolic processGO:200105730.019
regulation of transmembrane transportGO:00347621390.019
activation of protein kinase activityGO:0032147900.018
symbiosis encompassing mutualism through parasitismGO:00444031560.018
carboxylic acid biosynthetic processGO:0046394970.018
positive regulation of developmental processGO:00510943140.018
neurogenesisGO:00220081690.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
positive regulation of cellular component biogenesisGO:00440891580.018
hindbrain developmentGO:003090230.018
regulation of cytoskeleton organizationGO:00514931770.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
gtp catabolic processGO:00061842370.018
negative regulation of cellular amine metabolic processGO:003323930.018
calcium ion transportGO:00068161470.018
cardiovascular system developmentGO:00723582620.018
positive regulation of programmed cell deathGO:00430682490.018
modification dependent protein catabolic processGO:00199412090.018
proteasomal protein catabolic processGO:00104981760.018
carboxylic acid transportGO:0046942630.018
protein maturationGO:00516042330.018
somatic stem cell maintenanceGO:003501940.018
regulation of locomotionGO:00400123290.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
cytokine productionGO:00018162470.018
regulation of nucleoside metabolic processGO:00091182090.018
cellular response to endogenous stimulusGO:00714953360.018
motor neuron axon guidanceGO:000804520.018
organic hydroxy compound transportGO:0015850630.018
negative regulation of intracellular signal transductionGO:19025321830.018
peptidyl serine phosphorylationGO:00181051010.018
positive regulation of secretion by cellGO:19035321080.018
protein modification by small protein conjugationGO:00324463420.018
regulation of metal ion transportGO:00109591200.017
modification dependent macromolecule catabolic processGO:00436322120.017
regulation of vesicle mediated transportGO:00606271300.017
positive regulation of apoptotic processGO:00430652460.017
protein ubiquitinationGO:00165673140.017
regulation of cytokine productionGO:00018172320.017
cellular metal ion homeostasisGO:00068751460.017
erk1 and erk2 cascadeGO:00703711040.017
tripartite regional subdivisionGO:000735120.017
negative regulation of cell proliferationGO:00082852280.017
positive regulation of ion transportGO:0043270870.017
ubiquitin dependent protein catabolic processGO:00065112060.017
posttranscriptional regulation of gene expressionGO:00106082130.017
actin cytoskeleton organizationGO:00300362070.017
reactive oxygen species biosynthetic processGO:190340940.017
innate immune responseGO:00450871780.017
histone modificationGO:00165702510.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
regulation of cell growthGO:00015581350.017
negative regulation of cell cycleGO:00457861930.017
response to inorganic substanceGO:00100351270.017
anterior posterior axis specification embryoGO:000859520.017
regulation of anatomical structure sizeGO:00900661010.017
positive regulation of nucleoside metabolic processGO:00459791860.017
detection of chemical stimulus involved in sensory perceptionGO:0050907330.016
regulation of synaptic plasticityGO:004816730.016
peptidyl tyrosine modificationGO:00182121700.016
regulation of mitotic cell cycleGO:00073461890.016
regulation of gtp catabolic processGO:00331241800.016
sequestering of metal ionGO:0051238240.016
regulation of intracellular transportGO:00323861950.016
nucleoside monophosphate metabolic processGO:00091231910.016
alpha amino acid metabolic processGO:1901605720.016
rab protein signal transductionGO:003248240.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
circulatory system developmentGO:00723592620.016
regulation of cell morphogenesisGO:00226041530.016
nuclear transportGO:00511691790.016
response to woundingGO:00096111680.016
matingGO:000761810.016
photoreceptor cell differentiationGO:004653020.016
spermatid differentiationGO:004851540.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
tube closureGO:006060630.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
regulation of peptidase activityGO:00525471800.016
cellular response to external stimulusGO:00714961110.016
response to cytokineGO:00340972320.016
protein targetingGO:00066051870.016
regulation of erk1 and erk2 cascadeGO:0070372990.016
negative regulation of protein modification processGO:00314002000.016
peptidyl serine modificationGO:00182091060.016
spermatid developmentGO:000728640.015
organic acid biosynthetic processGO:0016053970.015
cell cycle phase transitionGO:00447701730.015
atp metabolic processGO:00460341760.015
regulation of protein catabolic processGO:00421761550.015
embryonic epithelial tube formationGO:000183840.015
regulation of apoptotic signaling pathwayGO:20012331750.015
negative regulation of phosphorylationGO:00423261740.015
interspecies interaction between organismsGO:00444191560.015
cellular response to abiotic stimulusGO:00712141170.015
covalent chromatin modificationGO:00165692540.015
behaviorGO:00076101120.015
syncytium formation by plasma membrane fusionGO:000076820.015
sulfur compound metabolic processGO:00067901010.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.015
regulation of neural precursor cell proliferationGO:200017740.015
positive regulation of axon extensionGO:004577340.015
monosaccharide metabolic processGO:0005996740.015
Yeast
positive regulation of erk1 and erk2 cascadeGO:0070374750.015
peripheral nervous system developmentGO:000742220.015
regulation of protein complex assemblyGO:00432541470.015
lung alveolus developmentGO:004828640.015
regulation of defense responseGO:00313471540.015
regulation of growthGO:00400081650.015
central nervous system developmentGO:00074171230.015
stem cell divisionGO:001714520.014
visual behaviorGO:000763220.014
organic hydroxy compound metabolic processGO:19016151470.014
regulation of axon guidanceGO:190266730.014
regulation of calcium ion transportGO:0051924790.014
neuron differentiationGO:00301821380.014
organic acid transportGO:0015849650.014
regulation of protein processingGO:00706131500.014
multi organism cellular processGO:00447641560.014
rhythmic behaviorGO:000762220.014
positive regulation of synaptic transmissionGO:005080640.014
neuroblast proliferationGO:000740540.014
somitogenesisGO:000175620.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
inorganic cation transmembrane transportGO:00986621940.014
nucleocytoplasmic transportGO:00069131760.014
cell growthGO:00160491600.014
regulation of purine nucleotide catabolic processGO:00331212050.014
sensory perceptionGO:00076001030.014
spinal cord developmentGO:002151040.014
regulation of axon extension involved in axon guidanceGO:004884120.014
nucleotide biosynthetic processGO:00091651090.014
neuron developmentGO:00486661130.014
positive regulation of gtp catabolic processGO:00331261660.014
cell divisionGO:00513011680.014
response to oxidative stressGO:00069791210.014
regulation of ion transmembrane transportGO:00347651320.014
embryonic placenta developmentGO:000189210.014
stress activated protein kinase signaling cascadeGO:0031098940.014
regulation of gtpase activityGO:00430871800.014
regulation of hormone levelsGO:00108171250.014
negative regulation of protein maturationGO:19033181420.014
cell activationGO:00017752130.014
i kappab kinase nf kappab signalingGO:00072491660.014
cell substrate adhesionGO:00315891320.014
positive regulation of cytosolic calcium ion concentrationGO:0007204820.014
nucleoside monophosphate catabolic processGO:00091251590.014
response to fungusGO:000962040.014
neural tube formationGO:000184130.014
positive regulation of nucleotide catabolic processGO:00308131850.013
anion transmembrane transportGO:0098656760.013
associative learningGO:000830610.013
sensory perception of painGO:001923340.013
mitochondrion organizationGO:00070051560.013
circulatory system processGO:00030131130.013
chemotaxisGO:00069351570.013
regulation of wnt signaling pathwayGO:00301111230.013
actin mediated cell contractionGO:0070252120.013
organelle fissionGO:00482851490.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
myoblast fusionGO:000752010.013
negative regulation of kinase activityGO:00336731060.013
negative regulation of protein phosphorylationGO:00019331400.013
nucleoside phosphate biosynthetic processGO:19012931090.013
cellular protein complex assemblyGO:00436231880.013
regulation of protein maturationGO:19033171500.013
response to lipidGO:00339932060.013
single organism cell adhesionGO:00986021790.013
peptidyl tyrosine phosphorylationGO:00181081700.013
positive regulation of immune system processGO:00026842830.013
regulation of ras protein signal transductionGO:00465781550.013
negative regulation of smoothened signaling pathwayGO:004587930.013
taxisGO:00423301570.013
calcium ion homeostasisGO:00550741220.013
primary neural tube formationGO:001402030.013
regulation of feeding behaviorGO:006025930.013
cellular response to cytokine stimulusGO:00713451810.013
lipid localizationGO:00108761060.013
cytosolic calcium ion homeostasisGO:0051480890.013
positive regulation of intracellular transportGO:00323881040.013
negative regulation of transferase activityGO:00513481240.013
positive regulation of cell differentiationGO:00455972110.013
regulation of peptidyl tyrosine phosphorylationGO:00507301080.013
mitotic cell cycle phase transitionGO:00447721620.013
endocytosisGO:00068971590.013
neuron projection regenerationGO:003110210.013
atp catabolic processGO:00062001570.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
cell type specific apoptotic processGO:00972851250.013
protein autophosphorylationGO:00467771230.013
establishment of protein localization to organelleGO:00725941720.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
neural tube closureGO:000184330.013
response to organic cyclic compoundGO:00140702040.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
serotonin transportGO:000683730.013
somatic muscle developmentGO:000752510.013
sequestering of calcium ionGO:0051208170.012
vasculature developmentGO:00019441810.012
rna processingGO:00063962550.012
nerve developmentGO:002167540.012
carbohydrate catabolic processGO:0016052360.012
Human
protein localization to membraneGO:00726571600.012
cellular carbohydrate metabolic processGO:0044262840.012
Human Rat
muscle system processGO:0003012810.012
tissue regenerationGO:004224630.012
protein homooligomerizationGO:00512601000.012
glycoprotein metabolic processGO:00091001100.012
positive regulation of secretionGO:00510471160.012
negative regulation of protein kinase activityGO:0006469980.012
circadian behaviorGO:004851220.012
generation of neuronsGO:00486991520.012
dna repairGO:00062811980.012
detection of stimulusGO:0051606850.012
positive regulation of neural precursor cell proliferationGO:200017920.012
cell fate determinationGO:000170930.012
negative regulation of peptidase activityGO:0010466910.012
limbic system developmentGO:002176130.012
signal releaseGO:0023061700.012
cell differentiation in spinal cordGO:002151510.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
anatomical structure homeostasisGO:00602491000.012
cellular response to lipidGO:00713961270.012
defense response to fungusGO:005083240.012
negative regulation of endopeptidase activityGO:0010951840.012
regulation of cell adhesionGO:00301551660.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
establishment of protein localization to membraneGO:00901501210.012
regulation of lipid metabolic processGO:0019216960.012
response to bacteriumGO:00096171440.012
response to growth factorGO:00708482050.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
sex determinationGO:000753030.012
protein localization to nucleusGO:00345041360.012
lipid transportGO:0006869900.012
blood circulationGO:00080151130.012
glial cell migrationGO:000834740.012
cellular response to nutrient levelsGO:0031669690.012
mitotic nuclear divisionGO:00070671190.012
morphogenesis of a polarized epitheliumGO:000173830.012
regulation of immune responseGO:00507762010.012
specification of organ identityGO:001009230.012
regulation of stress activated protein kinase signaling cascadeGO:0070302850.012
regulation of cytoplasmic transportGO:19036491490.012
negative regulation of proteolysisGO:00458611320.012
regulation of cell developmentGO:00602841610.012
calcium ion transmembrane transportGO:0070588760.012
response to virusGO:00096151260.012
positive regulation of proteolysisGO:00458621420.012
synaptic transmission cholinergicGO:000727120.012
methylationGO:00322591060.011
post embryonic organ developmentGO:004856910.011
negative regulation of developmental processGO:00510932470.011
positive regulation of immune responseGO:00507781590.011
protein targeting to nucleusGO:00447441040.011
retinal ganglion cell axon guidanceGO:003129020.011
rna interferenceGO:001624640.011
salivary gland morphogenesisGO:000743540.011
behavioral response to ethanolGO:004814920.011
regulation of map kinase activityGO:00434051080.011
epithelial cell differentiationGO:00308551410.011
muscle contractionGO:0006936730.011
regulation of neurotransmitter secretionGO:004692830.011
visual learningGO:000854210.011
response to nutrient levelsGO:0031667810.011
coenzyme metabolic processGO:0006732650.011
response to axon injuryGO:004867810.011
negative regulation of cell migrationGO:00303361020.011
positive regulation of cell migrationGO:00303351720.011
exocytosisGO:0006887710.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
leukocyte activationGO:00453211640.011
stress activated mapk cascadeGO:0051403930.011

PFKFB4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.047
inherited metabolic disorderDOID:6552420.028
nervous system diseaseDOID:8634310.028
central nervous system diseaseDOID:3311860.028
musculoskeletal system diseaseDOID:172230.019
cancerDOID:1621670.016
organ system cancerDOID:00506861640.016
disease of cellular proliferationDOID:145661740.016
brain diseaseDOID:936730.015
immune system diseaseDOID:29141550.015
neurodegenerative diseaseDOID:12891020.015
hematopoietic system diseaseDOID:741000.015
eye and adnexa diseaseDOID:14921500.014
sensory system diseaseDOID:00501552030.014
eye diseaseDOID:56141490.014
connective tissue diseaseDOID:651090.014
retinal diseaseDOID:56791180.014
bone diseaseDOID:0080001880.012