Homo sapiens

18 known processes

MAP3K9

mitogen-activated protein kinase kinase kinase 9

(Aliases: MEKK9,PRKE1,MLK1)

MAP3K9 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106410.085
cellular amino acid metabolic processGO:00065201160.079
regulation of cellular amine metabolic processGO:0033238110.078
post embryonic developmentGO:000979120.077
Fly
cellular ketone metabolic processGO:0042180800.073
purine containing compound catabolic processGO:00725234110.073
regulation of cellular amino acid metabolic processGO:000652160.067
amine metabolic processGO:0009308440.067
positive regulation of phosphorylationGO:00423273940.066
Human Fly
organophosphate catabolic processGO:00464344300.064
nucleoside phosphate catabolic processGO:19012924120.063
purine nucleotide catabolic processGO:00061954050.062
nucleotide catabolic processGO:00091664080.060
transmembrane transportGO:00550853990.060
regulation of cellular ketone metabolic processGO:0010565500.060
cation transportGO:00068123310.059
secretionGO:00469032540.059
small gtpase mediated signal transductionGO:0007264780.058
actin filament based processGO:00300292240.054
nucleoside catabolic processGO:00091644080.054
ras protein signal transductionGO:0007265730.054
nervous system developmentGO:00073992930.053
positive regulation of cellular amino acid metabolic processGO:004576430.052
ribonucleoside triphosphate metabolic processGO:00091994120.052
regulation of transferase activityGO:00513383550.052
Human Fly
ribonucleoside triphosphate catabolic processGO:00092033910.052
nucleoside triphosphate catabolic processGO:00091433940.051
cell developmentGO:00484683280.051
Fly
chemical homeostasisGO:00488783060.050
ion transmembrane transportGO:00342203380.049
response to oxygen containing compoundGO:19017003690.049
Fly
female gamete generationGO:000729220.049
Fly
locomotory behaviorGO:000762610.049
positive regulation of cellular amine metabolic processGO:003324070.049
ribonucleotide catabolic processGO:00092614050.049
purine nucleoside catabolic processGO:00061523980.049
cellular component morphogenesisGO:00329893140.049
Fly
oogenesisGO:004847720.049
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.048
glycosyl compound catabolic processGO:19016584130.048
purine ribonucleoside catabolic processGO:00461303980.048
purine ribonucleoside triphosphate catabolic processGO:00092073910.048
purine ribonucleotide catabolic processGO:00091544040.047
regulation of kinase activityGO:00435493140.047
Human Fly
purine ribonucleoside metabolic processGO:00461284370.047
purine nucleoside triphosphate metabolic processGO:00091444120.046
segmentationGO:003528240.046
multicellular organismal agingGO:001025930.045
cell projection organizationGO:00300302520.044
positive regulation of protein phosphorylationGO:00019343130.044
Human Fly
positive regulation of cellular component organizationGO:00511303760.044
regulation of cell cycleGO:00517263930.044
nucleoside triphosphate metabolic processGO:00091414220.044
determination of adult lifespanGO:000834020.043
regulation of protein kinase activityGO:00458592890.042
Human Fly
ribonucleoside catabolic processGO:00424544060.042
cellular response to dna damage stimulusGO:00069743790.041
vesicle mediated transportGO:00161923710.041
lipid metabolic processGO:00066293810.040
rho protein signal transductionGO:0007266260.040
system processGO:00030083490.039
negative regulation of protein metabolic processGO:00512483910.039
positive regulation of hydrolase activityGO:00513453310.038
positive regulation of kinase activityGO:00336742040.038
Human Fly
regulation of cell differentiationGO:00455953930.038
positive regulation of transportGO:00510503360.038
response to abiotic stimulusGO:00096283360.038
Fly
cell morphogenesisGO:00009022960.038
Fly
neuromuscular junction developmentGO:000752830.037
secretion by cellGO:00329402260.037
epithelium developmentGO:00604292270.037
Fly
regulation of cellular component movementGO:00512703340.037
signal transduction by phosphorylationGO:00230142970.037
Human Fly
memoryGO:000761330.036
mitotic cell cycleGO:00002783260.036
positive regulation of catabolic processGO:00098963100.036
cell adhesionGO:00071553250.036
cation transmembrane transportGO:00986552380.035
mapk cascadeGO:00001652880.035
Human Fly
purine nucleoside triphosphate catabolic processGO:00091463920.035
chromatin modificationGO:00165682980.034
inorganic ion transmembrane transportGO:00986602310.034
protein catabolic processGO:00301633250.033
positive regulation of protein kinase activityGO:00458601900.033
Human Fly
gtp catabolic processGO:00061842370.033
regulation of anatomical structure morphogenesisGO:00226032860.033
Fly
dephosphorylationGO:00163112090.033
regulation of mapk cascadeGO:00434082620.033
Human Fly
regulation of protein localizationGO:00328802960.033
positive regulation of purine nucleotide metabolic processGO:19005442270.033
negative regulation of catalytic activityGO:00430863350.032
regulation of secretionGO:00510461940.032
blastoderm segmentationGO:000735020.032
ion homeostasisGO:00508012300.032
negative regulation of multicellular organismal processGO:00512413170.032
inorganic cation transmembrane transportGO:00986621940.032
anatomical structure formation involved in morphogenesisGO:00486462840.032
Fly
monovalent inorganic cation transportGO:00156721280.031
regulation of ras protein signal transductionGO:00465781550.031
regulation of purine nucleotide metabolic processGO:19005422640.031
membrane organizationGO:00610242920.031
enzyme linked receptor protein signaling pathwayGO:00071673030.031
negative regulation of cellular protein metabolic processGO:00322693530.031
regulation of cellular component biogenesisGO:00440872810.031
metal ion transportGO:00300012720.030
neuron differentiationGO:00301821380.030
positive regulation of mapk cascadeGO:00434101900.030
Human Fly
negative regulation of cell deathGO:00605483450.030
regulation of nucleotide catabolic processGO:00308112050.030
regulation of locomotionGO:00400123290.030
negative regulation of phosphorus metabolic processGO:00105632670.030
cation homeostasisGO:00550801890.030
cytoplasmic transportGO:00164823790.029
regulation of cell motilityGO:20001452990.029
regulation of synaptic plasticityGO:004816730.029
cardiac muscle cell contractionGO:008600340.029
regulation of nucleoside metabolic processGO:00091182090.029
positive regulation of transferase activityGO:00513472270.029
Human Fly
positive regulation of developmental processGO:00510943140.029
cellular macromolecule catabolic processGO:00442653800.029
single organism cellular localizationGO:19025803320.029
gtp metabolic processGO:00460392390.029
biological adhesionGO:00226103310.029
regulation of nucleotide metabolic processGO:00061402690.029
regulation of cell migrationGO:00303342890.028
cellular lipid metabolic processGO:00442553030.028
positive regulation of nucleotide metabolic processGO:00459812300.028
negative regulation of phosphate metabolic processGO:00459362670.028
chromatin organizationGO:00063253510.028
guanosine containing compound metabolic processGO:19010682440.028
single organism membrane organizationGO:00448022680.028
oocyte differentiationGO:000999420.028
regulation of cellular response to stressGO:00801352440.027
Human Fly
negative regulation of apoptotic processGO:00430663160.027
regulation of protein serine threonine kinase activityGO:00719001790.026
Human Fly
anion transportGO:00068201610.026
protein ubiquitinationGO:00165673140.026
growthGO:00400072020.026
Fly
positive regulation of cellular catabolic processGO:00313312840.026
hindbrain developmentGO:003090230.026
protein modification by small protein conjugationGO:00324463420.026
positive regulation of nucleotide catabolic processGO:00308131850.025
oocyte developmentGO:004859910.025
nerve developmentGO:002167540.025
organelle assemblyGO:00709251760.025
rhythmic behaviorGO:000762220.025
cellular macromolecular complex assemblyGO:00346223240.025
actin cytoskeleton organizationGO:00300362070.025
generation of neuronsGO:00486991520.025
epithelial cell differentiationGO:00308551410.025
Fly
mitotic cell cycle processGO:19030472860.025
chemotaxisGO:00069351570.025
histone modificationGO:00165702510.025
matingGO:000761810.025
morphogenesis of embryonic epitheliumGO:001633140.025
Fly
dna repairGO:00062811980.024
apoptotic signaling pathwayGO:00971902680.024
cellular response to endogenous stimulusGO:00714953360.024
positive regulation of purine nucleotide catabolic processGO:00331231850.024
regulation of cell cycle processGO:00105642660.024
regulation of purine nucleotide catabolic processGO:00331212050.024
anterior posterior axis specificationGO:000994820.024
circadian behaviorGO:004851220.024
regulation of cell developmentGO:00602841610.023
microtubule based processGO:00070172100.023
Human
positive regulation of nucleoside metabolic processGO:00459791860.023
regulation of small gtpase mediated signal transductionGO:00510561560.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
guanosine containing compound catabolic processGO:19010692390.023
cellular homeostasisGO:00197251960.023
regulation of growthGO:00400081650.023
regenerationGO:003109940.023
positive regulation of immune system processGO:00026842830.023
intracellular protein transportGO:00068862700.023
positive regulation of cell differentiationGO:00455972110.023
covalent chromatin modificationGO:00165692540.022
positive regulation of synaptic transmissionGO:005080640.022
neurological system processGO:00508771630.022
cell cell signalingGO:00072671550.022
immune responseGO:00069553070.022
cellular response to oxygen containing compoundGO:19017012760.022
Fly
negative regulation of cell cycleGO:00457861930.022
negative regulation of programmed cell deathGO:00430693210.022
carbohydrate derivative biosynthetic processGO:19011372070.022
regulation of secretion by cellGO:19035301770.022
neurogenesisGO:00220081690.022
organophosphate biosynthetic processGO:00904071630.022
cellular cation homeostasisGO:00300031630.022
nitrogen compound transportGO:00717051910.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
organonitrogen compound biosynthetic processGO:19015662000.022
regulation of proteolysisGO:00301622930.022
regulation of establishment of protein localizationGO:00702012420.022
g protein coupled receptor signaling pathwayGO:00071862070.021
taxisGO:00423301570.021
regulation of ion transportGO:00432691890.021
negative regulation of cellular amine metabolic processGO:003323930.021
cellular chemical homeostasisGO:00550821800.021
cell part morphogenesisGO:00329901370.021
regulation of membrane potentialGO:0042391950.021
head developmentGO:00603221080.021
cell projection morphogenesisGO:00488581290.021
protein maturationGO:00516042330.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
negative regulation of transportGO:00510511760.021
cellular protein catabolic processGO:00442572610.020
peripheral nervous system developmentGO:000742220.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of cell deathGO:00109422630.020
circulatory system developmentGO:00723592620.020
regulation of cytokine productionGO:00018172320.020
actin mediated cell contractionGO:0070252120.020
negative regulation of protein modification processGO:00314002000.020
metal ion homeostasisGO:00550651690.020
protein localization to organelleGO:00333652800.020
cell cycle phase transitionGO:00447701730.020
sensory perception of painGO:001923340.020
cellular ion homeostasisGO:00068731680.019
regulation of mitotic cell cycleGO:00073461890.019
cell projection assemblyGO:00300311260.019
positive regulation of protein serine threonine kinase activityGO:00719021190.019
Human Fly
positive regulation of cell proliferationGO:00082843010.019
muscle contractionGO:0006936730.019
regulation of response to external stimulusGO:00321012220.019
cardiovascular system developmentGO:00723582620.019
cell divisionGO:00513011680.019
negative regulation of cell proliferationGO:00082852280.019
central nervous system developmentGO:00074171230.019
photoreceptor cell differentiationGO:004653020.019
carbohydrate metabolic processGO:00059752070.019
positive regulation of organelle organizationGO:00106381950.019
cranial nerve developmentGO:002154540.019
activation of protein kinase activityGO:0032147900.019
Human Fly
negative regulation of cellular component organizationGO:00511292350.019
anterior posterior axis specification embryoGO:000859520.019
cellular protein complex assemblyGO:00436231880.019
single organism carbohydrate metabolic processGO:00447231930.019
tissue morphogenesisGO:0048729960.019
Fly
nucleoside monophosphate catabolic processGO:00091251590.019
endomembrane system organizationGO:00102561960.019
organic hydroxy compound metabolic processGO:19016151470.019
positive regulation of programmed cell deathGO:00430682490.019
positive regulation of apoptotic processGO:00430652460.019
maintenance of locationGO:00512351120.019
adult locomotory behaviorGO:000834410.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
tripartite regional subdivisionGO:000735120.018
nucleoside monophosphate metabolic processGO:00091231910.018
regulation of cell morphogenesisGO:00226041530.018
Fly
proteolysis involved in cellular protein catabolic processGO:00516032440.018
lipid biosynthetic processGO:00086101770.018
associative learningGO:000830610.018
regulation of gtp catabolic processGO:00331241800.018
regulation of meiotic cell cycleGO:005144540.018
positive regulation of gtpase activityGO:00435471660.018
regulation of actin filament based processGO:00329701410.018
morphogenesis of a polarized epitheliumGO:000173830.018
reactive oxygen species biosynthetic processGO:190340940.018
protein targetingGO:00066051870.018
limbic system developmentGO:002176130.018
cell morphogenesis involved in differentiationGO:00009041440.018
reactive oxygen species metabolic processGO:0072593750.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
Human
negative regulation of phosphorylationGO:00423261740.018
modification dependent macromolecule catabolic processGO:00436322120.018
positive regulation of ras gtpase activityGO:00323201170.018
striated muscle contractionGO:0006941520.017
epidermis morphogenesisGO:004873030.017
protein processingGO:00164852260.017
potassium ion transportGO:0006813620.017
posttranscriptional regulation of gene expressionGO:00106082130.017
peptidyl tyrosine phosphorylationGO:00181081700.017
embryonic epithelial tube formationGO:000183840.017
atp metabolic processGO:00460341760.017
regulation of cytoskeleton organizationGO:00514931770.017
cell activationGO:00017752130.017
regulation of intracellular transportGO:00323861950.017
negative regulation of hydrolase activityGO:00513461820.017
neuron projection developmentGO:00311751060.017
regulation of protein transportGO:00512232130.017
sodium ion transmembrane transportGO:0035725590.017
cilium morphogenesisGO:0060271750.017
regulation of vesicle mediated transportGO:00606271300.017
reactive nitrogen species metabolic processGO:200105730.017
regulation of neurotransmitter secretionGO:004692830.017
regulation of gtpase activityGO:00430871800.017
defense responseGO:00069523150.017
cilium assemblyGO:0042384630.017
regulation of ras gtpase activityGO:00323181280.017
cellular response to growth factor stimulusGO:00713631970.017
small molecule biosynthetic processGO:00442831570.017
spermatid differentiationGO:004851540.017
thymus developmentGO:004853830.017
positive regulation of secretionGO:00510471160.016
endosomal transportGO:00161971290.016
innate immune responseGO:00450871780.016
establishment of protein localization to membraneGO:00901501210.016
response to nitrogen compoundGO:19016981840.016
protein autophosphorylationGO:00467771230.016
divalent inorganic cation homeostasisGO:00725071360.016
cytokine productionGO:00018162470.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
organ morphogenesisGO:00098871470.016
Fly
cell growthGO:00160491600.016
Fly
potassium ion transmembrane transportGO:0071805600.016
regulation of dna metabolic processGO:00510521530.016
spermatid developmentGO:000728640.016
mitotic cell cycle phase transitionGO:00447721620.016
neurotransmitter secretionGO:000726940.016
modification dependent protein catabolic processGO:00199412090.016
proteasomal protein catabolic processGO:00104981760.016
neural crest cell developmentGO:001403230.016
response to light stimulusGO:0009416870.016
neuron developmentGO:00486661130.016
response to radiationGO:00093141510.016
cellular potassium ion transportGO:0071804600.016
regulation of hormone levelsGO:00108171250.015
positive regulation of cell cycleGO:00457871400.015
regulation of transmembrane transportGO:00347621390.015
cardiac muscle contractionGO:0060048340.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
brain developmentGO:0007420970.015
motor neuron axon guidanceGO:000804520.015
response to organonitrogen compoundGO:00102431560.015
actin filament based movementGO:0030048170.015
cell fate determinationGO:000170930.015
positive regulation of cellular component biogenesisGO:00440891580.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of protein catabolic processGO:00421761550.015
positive regulation of gtp catabolic processGO:00331261660.015
ameboidal type cell migrationGO:00016671350.015
neuroblast proliferationGO:000740540.015
positive regulation of secretion by cellGO:19035321080.015
regulation of cell adhesionGO:00301551660.015
negative regulation of protein phosphorylationGO:00019331400.015
single organism cell adhesionGO:00986021790.015
rna processingGO:00063962550.015
tissue migrationGO:00901301190.015
salivary gland morphogenesisGO:000743540.015
regulation of feeding behaviorGO:006025930.015
endocytosisGO:00068971590.015
positive regulation of cellular component movementGO:00512721810.015
visual behaviorGO:000763220.014
ubiquitin dependent protein catabolic processGO:00065112060.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
leukocyte activationGO:00453211640.014
muscle system processGO:0003012810.014
peptidyl tyrosine modificationGO:00182121700.014
behaviorGO:00076101120.014
cilium organizationGO:0044782680.014
alcohol metabolic processGO:00060661140.014
organ formationGO:004864530.014
response to cytokineGO:00340972320.014
inner ear morphogenesisGO:004247240.014
negative regulation of transferase activityGO:00513481240.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
compound eye developmentGO:004874910.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
immune system developmentGO:00025201950.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
tissue regenerationGO:004224630.014
regulation of apoptotic signaling pathwayGO:20012331750.014
protein localization to membraneGO:00726571600.014
epithelial tube branching involved in lung morphogenesisGO:006044140.014
positive regulation of locomotionGO:00400171860.014
epithelial cell migrationGO:00106311190.014
epithelium migrationGO:00901321190.014
atp catabolic processGO:00062001570.014
positive regulation of protein transportGO:00512221350.014
hormone secretionGO:0046879650.014
cellular response to cytokine stimulusGO:00713451810.014
skin developmentGO:0043588760.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of protein complex assemblyGO:00432541470.014
divalent inorganic cation transportGO:00725111580.014
peptidyl serine phosphorylationGO:00181051010.014
Human
positive regulation of cell migrationGO:00303351720.014
negative regulation of developmental processGO:00510932470.014
vasculature developmentGO:00019441810.014
response to organic cyclic compoundGO:00140702040.014
positive regulation of cell motilityGO:20001471770.013
regulation of neuron differentiationGO:0045664700.013
divalent metal ion transportGO:00708381520.013
establishment or maintenance of apical basal cell polarityGO:003508820.013
regulation of peptidyl tyrosine phosphorylationGO:00507301080.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
nucleocytoplasmic transportGO:00069131760.013
nuclear transportGO:00511691790.013
specification of organ identityGO:001009230.013
regulation of system processGO:00440571010.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
calcium ion homeostasisGO:00550741220.013
regulation of cell projection organizationGO:00313441070.013
regulation of cell divisionGO:00513021160.013
long term memoryGO:000761620.013
response to woundingGO:00096111680.013
regulation of ion transmembrane transportGO:00347651320.013
establishment of planar polarityGO:000173630.013
regulation of neural precursor cell proliferationGO:200017740.013
negative regulation of protein processingGO:00109551420.013
regulation of protein maturationGO:19033171500.013
response to growth factorGO:00708482050.013
establishment of protein localization to organelleGO:00725941720.013
regulation of cell growthGO:00015581350.013
reproductive processGO:00224141060.013
Fly
negative regulation of synaptic transmissionGO:005080520.013
amide transportGO:0042886760.013
regulation of cytoplasmic transportGO:19036491490.013
regulation of peptidase activityGO:00525471800.013
multicellular organismal response to stressGO:003355510.013
monocarboxylic acid metabolic processGO:00327871850.013
positive regulation of proteolysisGO:00458621420.013
negative regulation of protein maturationGO:19033181420.013
regulation of map kinase activityGO:00434051080.013
Human Fly
visual learningGO:000854210.013
response to fungusGO:000962040.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
regulation of protein processingGO:00706131500.013
oxidation reduction processGO:00551143960.013
metencephalon developmentGO:002203720.012
sensory perceptionGO:00076001030.012
regulation of epithelial cell migrationGO:0010632930.012
response to biotic stimulusGO:00096072760.012
t cell differentiation in thymusGO:003307740.012
regulation of homeostatic processGO:00328441210.012
positive regulation of map kinase activityGO:0043406800.012
Human Fly
regulation of endopeptidase activityGO:00525481700.012
lung alveolus developmentGO:004828640.012
organic anion transportGO:00157111030.012
nucleotide biosynthetic processGO:00091651090.012
regulation of response to dna damage stimulusGO:2001020940.012
organelle fissionGO:00482851490.012
i kappab kinase nf kappab signalingGO:00072491660.012
sequestering of metal ionGO:0051238240.012
establishment of tissue polarityGO:000716430.012
peptidyl serine modificationGO:00182091060.012
Human
cellular metal ion homeostasisGO:00068751460.012
sleepGO:003043120.012
peptidyl lysine modificationGO:00182051440.012
meiotic chromosome segregationGO:004513240.012
cerebellum developmentGO:002154920.012
glycoprotein metabolic processGO:00091001100.012
response to external biotic stimulusGO:00432072610.012
epithelial cell proliferationGO:00506731280.012
response to axon injuryGO:004867810.012
regulation of dephosphorylationGO:0035303960.012
single organismal cell cell adhesionGO:00163371480.012
signal releaseGO:0023061700.012
mitochondrion organizationGO:00070051560.012
negative regulation of catabolic processGO:00098951040.012
neural tube formationGO:000184130.012
hormone transportGO:0009914680.012
syncytium formation by plasma membrane fusionGO:000076820.012
regulation of multi organism processGO:00439001570.012
regulation of nervous system developmentGO:0051960880.012
cell substrate adhesionGO:00315891320.012
stem cell divisionGO:001714520.012
synaptic transmission cholinergicGO:000727120.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
stress activated protein kinase signaling cascadeGO:0031098940.012
Human Fly
blood vessel developmentGO:00015681720.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
endothelial cell migrationGO:0043542860.012
peptide transportGO:0015833740.012
sequestering of calcium ionGO:0051208170.012
negative regulation of growthGO:0045926970.012
protein acylationGO:00435431380.012
negative regulation of kinase activityGO:00336731060.012
epidermis developmentGO:0008544590.011
sodium ion transportGO:0006814610.011
protein dephosphorylationGO:0006470810.011
carboxylic acid biosynthetic processGO:0046394970.011
cyclic nucleotide metabolic processGO:0009187820.011
protein oligomerizationGO:00512591730.011
regulation of bindingGO:00510981110.011
negative regulation of proteolysisGO:00458611320.011

MAP3K9 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.027
central nervous system diseaseDOID:3311860.027
sensory system diseaseDOID:00501552030.026
disease of metabolismDOID:00146672950.018
disease of cellular proliferationDOID:145661740.018
organ system cancerDOID:00506861640.018
cancerDOID:1621670.018
musculoskeletal system diseaseDOID:172230.018
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016
retinal diseaseDOID:56791180.015
inherited metabolic disorderDOID:6552420.014
connective tissue diseaseDOID:651090.014
neurodegenerative diseaseDOID:12891020.013
bone diseaseDOID:0080001880.012
brain diseaseDOID:936730.011