Homo sapiens

11 known processes

IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

(Aliases: D2HGA2,IDH,IDPM,mNADP-IDH,ICD-M,IDP,IDHM)

IDH2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.456
carboxylic acid catabolic processGO:0046395710.177
Yeast
lipid catabolic processGO:0016042840.168
Yeast
cofactor metabolic processGO:0051186870.132
small molecule catabolic processGO:0044282920.123
Yeast
organic acid catabolic processGO:0016054710.117
Yeast
fatty acid metabolic processGO:00066311150.115
Yeast
cellular ketone metabolic processGO:0042180800.115
single organism carbohydrate metabolic processGO:00447231930.099
determination of adult lifespanGO:000834020.094
generation of precursor metabolites and energyGO:0006091680.091
organic hydroxy compound metabolic processGO:19016151470.085
carbohydrate metabolic processGO:00059752070.074
regulation of hormone levelsGO:00108171250.071
energy derivation by oxidation of organic compoundsGO:0015980430.070
post embryonic developmentGO:000979120.069
cellular amino acid metabolic processGO:00065201160.064
multicellular organismal agingGO:001025930.058
tricarboxylic acid cycleGO:000609940.057
cellular lipid catabolic processGO:0044242650.056
Yeast
purine ribonucleoside metabolic processGO:00461284370.053
monocarboxylic acid metabolic processGO:00327871850.052
Yeast
lipid metabolic processGO:00066293810.049
Yeast
isocitrate metabolic processGO:000610210.047
Human Yeast
nucleoside triphosphate metabolic processGO:00091414220.042
negative regulation of transportGO:00510511760.041
oogenesisGO:004847720.041
cellular lipid metabolic processGO:00442553030.039
Yeast
regulation of secretion by cellGO:19035301770.039
response to oxygen containing compoundGO:19017003690.037
nitrogen compound transportGO:00717051910.036
ribonucleoside monophosphate metabolic processGO:00091611870.036
regulation of secretionGO:00510461940.036
purine nucleoside triphosphate metabolic processGO:00091444120.034
ion transmembrane transportGO:00342203380.034
amine metabolic processGO:0009308440.034
cellular amine metabolic processGO:0044106410.034
secretion by cellGO:00329402260.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.033
negative regulation of programmed cell deathGO:00430693210.033
nervous system developmentGO:00073992930.033
cellular carbohydrate metabolic processGO:0044262840.032
regulation of hormone secretionGO:0046883570.031
protein tetramerizationGO:0051262470.031
response to hormoneGO:00097251750.030
regulation of cellular amino acid metabolic processGO:000652160.030
secretionGO:00469032540.030
citrate metabolic processGO:000610120.030
regulation of cellular amine metabolic processGO:0033238110.029
negative regulation of catalytic activityGO:00430863350.029
ribonucleoside triphosphate metabolic processGO:00091994120.028
dephosphorylationGO:00163112090.028
coenzyme metabolic processGO:0006732650.028
cell developmentGO:00484683280.028
organophosphate biosynthetic processGO:00904071630.027
neuroblast proliferationGO:000740540.027
chemical homeostasisGO:00488783060.027
organophosphate catabolic processGO:00464344300.027
female gamete generationGO:000729220.027
carbohydrate derivative biosynthetic processGO:19011372070.027
negative regulation of cellular protein metabolic processGO:00322693530.026
amide transportGO:0042886760.026
steroid metabolic processGO:0008202940.026
insulin secretionGO:0030073390.026
signal releaseGO:0023061700.025
protein oligomerizationGO:00512591730.025
regulation of cellular ketone metabolic processGO:0010565500.025
positive regulation of cellular amino acid metabolic processGO:004576430.024
positive regulation of cell deathGO:00109422630.024
doxorubicin metabolic processGO:004459880.024
negative regulation of protein metabolic processGO:00512483910.024
biological adhesionGO:00226103310.024
atp metabolic processGO:00460341760.024
organic acid biosynthetic processGO:0016053970.023
organelle assemblyGO:00709251760.023
response to activityGO:001482300.023
organonitrogen compound biosynthetic processGO:19015662000.023
apoptotic signaling pathwayGO:00971902680.023
generation of neuronsGO:00486991520.023
epithelium developmentGO:00604292270.023
cellular protein complex assemblyGO:00436231880.022
positive regulation of apoptotic processGO:00430652460.022
regulation of neural precursor cell proliferationGO:200017740.022
cellular component morphogenesisGO:00329893140.022
peptide transportGO:0015833740.022
nucleotide biosynthetic processGO:00091651090.022
segmentationGO:003528240.022
transmembrane transportGO:00550853990.022
protein processingGO:00164852260.022
microtubule based processGO:00070172100.022
system processGO:00030083490.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
oxidoreduction coenzyme metabolic processGO:0006733190.021
negative regulation of cell deathGO:00605483450.021
negative regulation of phosphate metabolic processGO:00459362670.021
actin filament based processGO:00300292240.021
positive regulation of cellular amine metabolic processGO:003324070.021
reactive oxygen species metabolic processGO:0072593750.021
fatty acid oxidationGO:0019395310.021
Yeast
ras protein signal transductionGO:0007265730.021
nucleoside phosphate biosynthetic processGO:19012931090.021
cation transportGO:00068123310.020
organic anion transportGO:00157111030.020
regulation of cell cycle processGO:00105642660.020
protein homooligomerizationGO:00512601000.020
neuromuscular junction developmentGO:000752830.020
cellular macromolecular complex assemblyGO:00346223240.020
regulation of transferase activityGO:00513383550.020
negative regulation of developmental processGO:00510932470.019
regulation of proteolysisGO:00301622930.019
glycoside metabolic processGO:0016137130.019
cell cell signalingGO:00072671550.019
alcohol metabolic processGO:00060661140.019
negative regulation of apoptotic processGO:00430663160.019
negative regulation of protein modification processGO:00314002000.019
regulation of peptidase activityGO:00525471800.019
response to organonitrogen compoundGO:00102431560.019
anion transportGO:00068201610.019
negative regulation of multicellular organismal processGO:00512413170.019
regulation of insulin secretionGO:0050796330.019
locomotory behaviorGO:000762610.019
response to abiotic stimulusGO:00096283360.019
nucleoside phosphate catabolic processGO:19012924120.019
negative regulation of phosphorus metabolic processGO:00105632670.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
ribonucleotide catabolic processGO:00092614050.018
endomembrane system organizationGO:00102561960.018
negative regulation of secretion by cellGO:1903531520.018
cellular respirationGO:0045333210.018
mitotic cell cycle processGO:19030472860.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
cell morphogenesisGO:00009022960.017
polyketide metabolic processGO:003063880.017
positive regulation of hydrolase activityGO:00513453310.017
aerobic respirationGO:000906070.017
nucleoside monophosphate metabolic processGO:00091231910.017
protein maturationGO:00516042330.017
regulation of kinase activityGO:00435493140.017
regulation of endopeptidase activityGO:00525481700.017
regulation of cell cycleGO:00517263930.017
pyruvate metabolic processGO:0006090260.017
regulation of peptide secretionGO:0002791420.017
neuron differentiationGO:00301821380.017
peptide secretionGO:0002790510.017
regulation of peptide transportGO:0090087620.017
regulation of cell differentiationGO:00455953930.017
carbohydrate catabolic processGO:0016052360.017
response to axon injuryGO:004867810.017
multicellular organismal homeostasisGO:0048871670.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
regenerationGO:003109940.017
carboxylic acid biosynthetic processGO:0046394970.017
myosin filament organizationGO:003103320.016
cellular response to dna damage stimulusGO:00069743790.016
response to drugGO:0042493810.016
alpha amino acid metabolic processGO:1901605720.016
positive regulation of cellular component organizationGO:00511303760.016
purine containing compound catabolic processGO:00725234110.016
striated muscle myosin thick filament assemblyGO:007168820.016
nucleotide catabolic processGO:00091664080.016
positive regulation of transportGO:00510503360.016
cell adhesionGO:00071553250.016
tricarboxylic acid metabolic processGO:007235040.016
Human Yeast
reactive nitrogen species metabolic processGO:200105730.016
pyridine nucleotide metabolic processGO:0019362140.016
regulation of peptide hormone secretionGO:0090276410.016
cell activationGO:00017752130.016
defense responseGO:00069523150.015
cell projection organizationGO:00300302520.015
regulation of protein kinase activityGO:00458592890.015
regulation of nucleoside metabolic processGO:00091182090.015
negative regulation of hydrolase activityGO:00513461820.015
positive regulation of phosphorylationGO:00423273940.015
regulation of protein serine threonine kinase activityGO:00719001790.015
positive regulation of programmed cell deathGO:00430682490.015
actin cytoskeleton organizationGO:00300362070.015
small molecule biosynthetic processGO:00442831570.015
purine nucleoside monophosphate metabolic processGO:00091261860.014
regulation of anatomical structure morphogenesisGO:00226032860.014
neurogenesisGO:00220081690.014
cellular macromolecule catabolic processGO:00442653800.014
thymus developmentGO:004853830.014
negative regulation of secretionGO:0051048580.014
mapk cascadeGO:00001652880.014
epithelial cell differentiationGO:00308551410.014
response to external biotic stimulusGO:00432072610.014
cellular amino acid catabolic processGO:0009063310.014
membrane organizationGO:00610242920.014
single organism carbohydrate catabolic processGO:0044724330.014
sulfur compound metabolic processGO:00067901010.014
cell divisionGO:00513011680.014
response to biotic stimulusGO:00096072760.014
monosaccharide metabolic processGO:0005996740.014
positive regulation of protein phosphorylationGO:00019343130.014
rna interferenceGO:001624640.014
lipid biosynthetic processGO:00086101770.014
single organism cellular localizationGO:19025803320.013
regulation of cell developmentGO:00602841610.013
inorganic ion transmembrane transportGO:00986602310.013
response to nitrogen compoundGO:19016981840.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
cellular chemical homeostasisGO:00550821800.013
regulation of cell adhesionGO:00301551660.013
hemopoiesisGO:00300971800.013
small gtpase mediated signal transductionGO:0007264780.013
negative regulation of intracellular signal transductionGO:19025321830.013
microtubule cytoskeleton organizationGO:00002261760.013
adult locomotory behaviorGO:000834410.013
cellular response to nutrient levelsGO:0031669690.013
immune responseGO:00069553070.013
mitochondrial transportGO:0006839600.013
negative regulation of transferase activityGO:00513481240.013
2 oxoglutarate metabolic processGO:000610340.013
Human
pyridine containing compound metabolic processGO:0072524180.013
proteasomal protein catabolic processGO:00104981760.013
sensory perception of painGO:001923340.013
regulation of synaptic plasticityGO:004816730.013
mitotic cell cycleGO:00002783260.013
regulation of cysteine type endopeptidase activityGO:20001161270.012
response to inorganic substanceGO:00100351270.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
negative regulation of phosphorylationGO:00423261740.012
protein catabolic processGO:00301633250.012
reproductive processGO:00224141060.012
response to woundingGO:00096111680.012
positive regulation of mapk cascadeGO:00434101900.012
regulation of cell motilityGO:20001452990.012
quinone metabolic processGO:1901661180.012
cell projection morphogenesisGO:00488581290.012
glycosyl compound catabolic processGO:19016584130.012
positive regulation of immune system processGO:00026842830.012
embryo developmentGO:00097901230.012
inorganic cation transmembrane transportGO:00986621940.012
positive regulation of kinase activityGO:00336742040.012
signal transduction by phosphorylationGO:00230142970.012
regulation of apoptotic signaling pathwayGO:20012331750.012
single organism membrane organizationGO:00448022680.012
purine containing compound biosynthetic processGO:0072522880.012
positive regulation of developmental processGO:00510943140.012
growthGO:00400072020.012
peripheral nervous system developmentGO:000742220.011
positive regulation of cell proliferationGO:00082843010.011
response to metal ionGO:0010038840.011
hormone secretionGO:0046879650.011
neurological system processGO:00508771630.011
negative regulation of growthGO:0045926970.011
regulation of neuroblast proliferationGO:190269230.011
negative regulation of cell proliferationGO:00082852280.011
negative regulation of cellular amine metabolic processGO:003323930.011
cytoplasmic transportGO:00164823790.011
regulation of purine nucleotide catabolic processGO:00331212050.011
cell part morphogenesisGO:00329901370.011
cellular response to endogenous stimulusGO:00714953360.011
cellular homeostasisGO:00197251960.011
guanosine containing compound catabolic processGO:19010692390.011
negative regulation of cell differentiationGO:00455961710.011
spinal cord developmentGO:002151040.011
purine nucleotide catabolic processGO:00061954050.011
regulation of cell morphogenesisGO:00226041530.011
regulation of cellular component biogenesisGO:00440872810.011
positive regulation of synaptic transmissionGO:005080640.011
regulation of cellular response to stressGO:00801352440.011
hexose metabolic processGO:0019318550.011
glycerolipid metabolic processGO:00464861070.011
aminoglycoside antibiotic metabolic processGO:003064780.011
cell growthGO:00160491600.011
ion homeostasisGO:00508012300.011
negative regulation of cellular component organizationGO:00511292350.011
hemostasisGO:0007599760.011
metencephalon developmentGO:002203720.010
protein homotetramerizationGO:0051289280.010
regulation of protein maturationGO:19033171500.010
positive regulation of transferase activityGO:00513472270.010
metal ion transportGO:00300012720.010
regulation of mapk cascadeGO:00434082620.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
spermatid developmentGO:000728640.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
reactive oxygen species biosynthetic processGO:190340940.010

IDH2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.665
inherited metabolic disorderDOID:6552420.665
amino acid metabolic disorderDOID:9252500.190
carbohydrate metabolic disorderDOID:2978550.083
disease of cellular proliferationDOID:145661740.027
Human
cancerDOID:1621670.027
Human
musculoskeletal system diseaseDOID:172230.026
organ system cancerDOID:00506861640.025
urinary system diseaseDOID:18400.021
sensory system diseaseDOID:00501552030.020
nervous system diseaseDOID:8634310.020
eye diseaseDOID:56141490.020
eye and adnexa diseaseDOID:14921500.020
muscle tissue diseaseDOID:661130.017
muscular diseaseDOID:00800001140.017
myopathyDOID:4231040.017
hyperinsulinemic hypoglycemiaDOID:1331770.016
cardiovascular system diseaseDOID:12871060.015
central nervous system diseaseDOID:3311860.015
immune system diseaseDOID:29141550.014
retinal diseaseDOID:56791180.010
2 hydroxyglutaric aciduriaDOID:005057330.001