Homo sapiens

0 known processes

PRSS23

protease, serine, 23

(Aliases: SIG13,SPUVE,MGC5107,ZSIG13)

PRSS23 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell adhesionGO:00071553250.376
anatomical structure formation involved in morphogenesisGO:00486462840.353
post embryonic developmentGO:000979120.288
circulatory system developmentGO:00723592620.196
rho protein signal transductionGO:0007266260.195
cardiovascular system developmentGO:00723582620.193
blood vessel developmentGO:00015681720.166
regulation of cell differentiationGO:00455953930.155
positive regulation of developmental processGO:00510943140.138
cellular component morphogenesisGO:00329893140.127
negative regulation of cell proliferationGO:00082852280.121
vasculature developmentGO:00019441810.119
transmembrane transportGO:00550853990.117
cell developmentGO:00484683280.116
ion transmembrane transportGO:00342203380.116
epithelium developmentGO:00604292270.108
cation transportGO:00068123310.108
small gtpase mediated signal transductionGO:0007264780.105
cytoplasmic transportGO:00164823790.100
response to oxygen containing compoundGO:19017003690.098
positive regulation of cellular amine metabolic processGO:003324070.095
negative regulation of multicellular organismal processGO:00512413170.091
purine ribonucleotide catabolic processGO:00091544040.086
system processGO:00030083490.086
cell morphogenesisGO:00009022960.085
regulation of cellular ketone metabolic processGO:0010565500.085
organophosphate catabolic processGO:00464344300.085
biological adhesionGO:00226103310.084
enzyme linked receptor protein signaling pathwayGO:00071673030.084
purine ribonucleoside triphosphate metabolic processGO:00092054110.083
regulation of cell adhesionGO:00301551660.082
regulation of cellular amine metabolic processGO:0033238110.082
detection of stimulusGO:0051606850.082
regulation of cellular amino acid metabolic processGO:000652160.080
glycosyl compound catabolic processGO:19016584130.080
nucleoside phosphate catabolic processGO:19012924120.080
cellular ketone metabolic processGO:0042180800.080
purine nucleotide catabolic processGO:00061954050.078
regulation of ion transmembrane transportGO:00347651320.077
positive regulation of cellular amino acid metabolic processGO:004576430.074
cellular amine metabolic processGO:0044106410.073
cellular amino acid metabolic processGO:00065201160.072
regulation of anatomical structure morphogenesisGO:00226032860.072
vesicle mediated transportGO:00161923710.071
purine ribonucleoside catabolic processGO:00461303980.070
ras protein signal transductionGO:0007265730.070
regulation of cell migrationGO:00303342890.067
plasma membrane organizationGO:00070091150.066
regulation of locomotionGO:00400123290.064
nucleotide catabolic processGO:00091664080.063
positive regulation of cell differentiationGO:00455972110.063
cell projection organizationGO:00300302520.062
segmentationGO:003528240.062
cellular response to oxygen containing compoundGO:19017012760.062
immune responseGO:00069553070.061
endomembrane system organizationGO:00102561960.061
cation homeostasisGO:00550801890.061
nucleoside catabolic processGO:00091644080.060
membrane organizationGO:00610242920.059
ion homeostasisGO:00508012300.059
single organism membrane organizationGO:00448022680.058
response to abiotic stimulusGO:00096283360.057
ribonucleoside triphosphate metabolic processGO:00091994120.057
ameboidal type cell migrationGO:00016671350.056
purine containing compound catabolic processGO:00725234110.056
cell substrate adhesionGO:00315891320.056
ribonucleoside catabolic processGO:00424544060.055
regulation of cellular component movementGO:00512703340.055
positive regulation of phosphorylationGO:00423273940.055
response to growth factorGO:00708482050.055
regulation of cell motilityGO:20001452990.054
negative regulation of cell differentiationGO:00455961710.053
purine nucleoside catabolic processGO:00061523980.053
positive regulation of immune system processGO:00026842830.053
amine metabolic processGO:0009308440.053
negative regulation of catalytic activityGO:00430863350.053
blood vessel morphogenesisGO:00485141620.053
positive regulation of programmed cell deathGO:00430682490.052
response to woundingGO:00096111680.052
ribonucleotide catabolic processGO:00092614050.052
actin filament based processGO:00300292240.052
protein localization to membraneGO:00726571600.051
purine ribonucleoside triphosphate catabolic processGO:00092073910.050
neurological system processGO:00508771630.050
regulation of response to external stimulusGO:00321012220.049
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.049
regenerationGO:003109940.049
inorganic cation transmembrane transportGO:00986621940.048
dna packagingGO:0006323770.048
chemical homeostasisGO:00488783060.048
ribonucleoside triphosphate catabolic processGO:00092033910.047
cell morphogenesis involved in differentiationGO:00009041440.047
multicellular organismal homeostasisGO:0048871670.047
negative regulation of transportGO:00510511760.047
nucleoside triphosphate catabolic processGO:00091433940.046
purine ribonucleoside metabolic processGO:00461284370.046
angiogenesisGO:00015251470.045
positive regulation of protein phosphorylationGO:00019343130.045
tachykinin receptor signaling pathwayGO:000721730.045
negative regulation of phosphorus metabolic processGO:00105632670.044
anion transportGO:00068201610.044
cardiac right ventricle morphogenesisGO:000321530.044
regulation of nucleotide metabolic processGO:00061402690.044
negative regulation of cell migrationGO:00303361020.043
regulation of transporter activityGO:0032409820.043
nucleoside triphosphate metabolic processGO:00091414220.043
inorganic ion transmembrane transportGO:00986602310.043
regulation of purine nucleotide metabolic processGO:19005422640.042
single organismal cell cell adhesionGO:00163371480.042
regulation of transmembrane transporter activityGO:0022898740.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
single organism cellular localizationGO:19025803320.041
regulation of transmembrane transportGO:00347621390.041
mitotic cell cycleGO:00002783260.041
regulation of ion transportGO:00432691890.040
positive regulation of locomotionGO:00400171860.039
muscle structure developmentGO:0061061980.039
response to biotic stimulusGO:00096072760.039
defense responseGO:00069523150.039
wnt signaling pathwayGO:00160551560.039
dna conformation changeGO:00711031130.038
protein localization to plasma membraneGO:0072659930.038
cell activationGO:00017752130.038
regulation of establishment of protein localizationGO:00702012420.038
negative regulation of protein metabolic processGO:00512483910.038
blood circulationGO:00080151130.038
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.038
matingGO:000761810.037
negative regulation of cell deathGO:00605483450.037
organelle assemblyGO:00709251760.037
establishment of protein localization to membraneGO:00901501210.037
circulatory system processGO:00030131130.037
positive regulation of cytokine productionGO:00018191670.036
organ morphogenesisGO:00098871470.036
negative regulation of immune system processGO:00026831360.036
negative regulation of cellular component movementGO:00512711060.036
purine nucleoside triphosphate catabolic processGO:00091463920.036
regulation of cell morphogenesisGO:00226041530.036
dephosphorylationGO:00163112090.036
response to radiationGO:00093141510.036
positive regulation of transportGO:00510503360.036
taxisGO:00423301570.035
response to other organismGO:00517072610.035
intracellular protein transportGO:00068862700.035
regulation of cytokine productionGO:00018172320.035
organonitrogen compound biosynthetic processGO:19015662000.035
cytokine productionGO:00018162470.035
somitogenesisGO:000175620.034
cellular response to growth factor stimulusGO:00713631970.034
positive regulation of cell motilityGO:20001471770.034
muscle contractionGO:0006936730.034
regulation of canonical wnt signaling pathwayGO:0060828880.034
regulation of wnt signaling pathwayGO:00301111230.034
cellular component assembly involved in morphogenesisGO:0010927730.034
positive regulation of cellular component organizationGO:00511303760.034
maintenance of locationGO:00512351120.034
actin cytoskeleton organizationGO:00300362070.033
negative regulation of programmed cell deathGO:00430693210.033
cellular response to endogenous stimulusGO:00714953360.033
regulation of protein localizationGO:00328802960.033
mitotic cell cycle processGO:19030472860.033
secretion by cellGO:00329402260.032
establishment of protein localization to plasma membraneGO:0090002680.032
tube developmentGO:00352951250.032
female gamete generationGO:000729220.032
cation transmembrane transportGO:00986552380.032
regulation of kinase activityGO:00435493140.031
positive regulation of transferase activityGO:00513472270.031
hematopoietic or lymphoid organ developmentGO:00485341860.031
metal ion homeostasisGO:00550651690.031
positive regulation of cell proliferationGO:00082843010.031
cellular response to transforming growth factor beta stimulusGO:0071560940.031
regulation of protein kinase activityGO:00458592890.031
negative regulation of phosphate metabolic processGO:00459362670.031
protein maturationGO:00516042330.031
cardiac muscle contractionGO:0060048340.031
response to external biotic stimulusGO:00432072610.031
protein localization to nucleusGO:00345041360.030
regulation of leukocyte activationGO:00026941150.030
striated muscle contractionGO:0006941520.030
oogenesisGO:004847720.030
chemotaxisGO:00069351570.030
endothelial cell migrationGO:0043542860.030
determination of adult lifespanGO:000834020.030
salivary gland morphogenesisGO:000743540.030
apoptotic signaling pathwayGO:00971902680.030
sodium ion transportGO:0006814610.030
positive regulation of hydrolase activityGO:00513453310.029
regulation of sequence specific dna binding transcription factor activityGO:00510902110.029
gtp catabolic processGO:00061842370.029
negative regulation of intracellular signal transductionGO:19025321830.029
locomotory behaviorGO:000762610.029
muscle system processGO:0003012810.029
multicellular organismal agingGO:001025930.028
secretionGO:00469032540.028
sodium ion transmembrane transportGO:0035725590.028
protein importGO:00170381300.028
regulation of purine nucleotide catabolic processGO:00331212050.028
tissue morphogenesisGO:0048729960.028
regulation of actin cytoskeleton organizationGO:00329561160.028
carbohydrate metabolic processGO:00059752070.027
regulation of protein transportGO:00512232130.027
nervous system developmentGO:00073992930.027
neuromuscular junction developmentGO:000752830.027
heart developmentGO:0007507950.027
heart morphogenesisGO:0003007480.027
detection of chemical stimulus involved in sensory perceptionGO:0050907330.027
wound healingGO:00420601150.027
negative regulation of locomotionGO:00400131180.027
positive regulation of nucleotide metabolic processGO:00459812300.027
positive regulation of cellular component movementGO:00512721810.027
striated muscle cell differentiationGO:0051146430.027
regulation of immune responseGO:00507762010.027
peptidyl tyrosine phosphorylationGO:00181081700.027
hemopoiesisGO:00300971800.027
regulation of ras gtpase activityGO:00323181280.027
regulation of intracellular transportGO:00323861950.026
positive regulation of apoptotic processGO:00430652460.026
negative regulation of apoptotic processGO:00430663160.026
anatomical structure homeostasisGO:00602491000.026
endocytosisGO:00068971590.026
negative regulation of cellular protein metabolic processGO:00322693530.026
protein refoldingGO:0042026140.026
negative regulation of hydrolase activityGO:00513461820.026
cell matrix adhesionGO:0007160850.026
regulation of metal ion transportGO:00109591200.026
regulation of transferase activityGO:00513383550.026
generation of neuronsGO:00486991520.026
regulation of ras protein signal transductionGO:00465781550.026
single organism cell adhesionGO:00986021790.026
t cell differentiation in thymusGO:003307740.025
response to organic cyclic compoundGO:00140702040.025
nucleoside monophosphate catabolic processGO:00091251590.025
epithelium migrationGO:00901321190.025
positive regulation of cell migrationGO:00303351720.025
cellular chemical homeostasisGO:00550821800.025
regulation of actin filament based processGO:00329701410.025
response to lipidGO:00339932060.025
monovalent inorganic cation transportGO:00156721280.025
posttranscriptional regulation of gene expressionGO:00106082130.025
response to metal ionGO:0010038840.025
regulation of cell activationGO:00508651250.025
immune system developmentGO:00025201950.025
golgi vesicle transportGO:0048193800.025
neuroblast proliferationGO:000740540.025
cell fate determinationGO:000170930.024
positive regulation of catabolic processGO:00098963100.024
negative regulation of developmental processGO:00510932470.024
regulation of intracellular protein transportGO:00331571230.024
cilium assemblyGO:0042384630.024
response to acid chemicalGO:0001101660.024
regulation of gtpase activityGO:00430871800.024
leukocyte activationGO:00453211640.024
regulation of cell developmentGO:00602841610.024
actin filament based movementGO:0030048170.024
ribonucleoside monophosphate metabolic processGO:00091611870.023
covalent chromatin modificationGO:00165692540.023
nitrogen compound transportGO:00717051910.023
tissue homeostasisGO:0001894630.023
regulation of cytoplasmic transportGO:19036491490.023
signal transduction by phosphorylationGO:00230142970.023
regulation of nucleoside metabolic processGO:00091182090.023
response to nitrogen compoundGO:19016981840.023
cilium morphogenesisGO:0060271750.023
detection of mechanical stimulusGO:005098240.023
innate immune responseGO:00450871780.023
canonical wnt signaling pathwayGO:00600701160.023
purine ribonucleoside monophosphate metabolic processGO:00091671860.023
regulation of cellular component biogenesisGO:00440872810.022
regulation of system processGO:00440571010.022
cellular ion homeostasisGO:00068731680.022
actin mediated cell contractionGO:0070252120.022
cdc42 protein signal transductionGO:003248840.022
response to calcium ionGO:0051592460.022
cellular response to dna damage stimulusGO:00069743790.022
muscle tissue developmentGO:0060537620.022
regulation of peptidyl tyrosine phosphorylationGO:00507301080.022
regulation of cell cycle processGO:00105642660.022
regulation of defense responseGO:00313471540.022
second messenger mediated signalingGO:0019932780.022
carbohydrate derivative biosynthetic processGO:19011372070.022
receptor mediated endocytosisGO:0006898840.022
regulation of rho protein signal transductionGO:0035023790.022
embryo developmentGO:00097901230.022
protein targeting to nucleusGO:00447441040.021
cell projection morphogenesisGO:00488581290.021
cell growthGO:00160491600.021
regulation of small gtpase mediated signal transductionGO:00510561560.021
positive regulation of protein kinase activityGO:00458601900.021
atp catabolic processGO:00062001570.021
stem cell differentiationGO:0048863930.021
positive regulation of leukocyte activationGO:0002696800.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
purine nucleoside monophosphate catabolic processGO:00091281580.021
inner ear morphogenesisGO:004247240.021
single organism carbohydrate metabolic processGO:00447231930.021
regulation of body fluid levelsGO:0050878990.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.021
positive regulation of ion transmembrane transporter activityGO:0032414290.021
protein targetingGO:00066051870.021
protein processingGO:00164852260.021
small molecule biosynthetic processGO:00442831570.021
regulation of cytoskeleton organizationGO:00514931770.021
chromatin organizationGO:00063253510.020
mesenchymal cell developmentGO:0014031500.020
positive regulation of cellular catabolic processGO:00313312840.020
protein import into nucleusGO:00066061040.020
regulation of proteolysisGO:00301622930.020
single organism nuclear importGO:19025931040.020
protein o linked glycosylation via serineGO:001824230.020
purine nucleoside monophosphate metabolic processGO:00091261860.020
negative regulation of cell motilityGO:20001461040.020
somatic muscle developmentGO:000752510.020
regulation of epithelial cell migrationGO:0010632930.020
cellular macromolecular complex assemblyGO:00346223240.020
response to hormoneGO:00097251750.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
nuclear importGO:00511701060.020
ribonucleoside monophosphate catabolic processGO:00091581580.020
leukocyte differentiationGO:0002521980.020
regulation of cell cycleGO:00517263930.020
positive regulation of ion transportGO:0043270870.020
heart contractionGO:0060047620.020
multicellular organismal response to stressGO:003355510.020
epithelial cell migrationGO:00106311190.019
cellular response to lipidGO:00713961270.019
memoryGO:000761330.019
soft palate developmentGO:006002330.019
regulation of vasculature developmentGO:1901342970.019
blastoderm segmentationGO:000735020.019
regulation of cell substrate adhesionGO:0010810680.019
lipid metabolic processGO:00066293810.019
negative regulation of cellular amine metabolic processGO:003323930.019
response to inorganic substanceGO:00100351270.019
protein homooligomerizationGO:00512601000.019
nerve developmentGO:002167540.019
retina homeostasisGO:0001895420.019
morphogenesis of embryonic epitheliumGO:001633140.019
ossificationGO:00015031210.019
response to transforming growth factor betaGO:0071559940.019
neuron developmentGO:00486661130.019
mapk cascadeGO:00001652880.019
regulation of cell morphogenesis involved in differentiationGO:0010769830.019
response to cytokineGO:00340972320.019
cilium organizationGO:0044782680.018
regulation of protein import into nucleusGO:0042306780.018
mesenchyme developmentGO:0060485590.018
antigen processing and presentation via mhc class ibGO:000247530.018
negative regulation of calcium mediated signalingGO:005084940.018
positive regulation of immune responseGO:00507781590.018
tissue migrationGO:00901301190.018
growthGO:00400072020.018
negative regulation of wnt signaling pathwayGO:0030178690.018
cell part morphogenesisGO:00329901370.018
protein localization to organelleGO:00333652800.018
tissue regenerationGO:004224630.018
head developmentGO:00603221080.018
response to organonitrogen compoundGO:00102431560.018
regulation of cell adhesion mediated by integrinGO:0033628220.018
regulation of endopeptidase activityGO:00525481700.018
gtp metabolic processGO:00460392390.018
purine ribonucleoside monophosphate catabolic processGO:00091691580.018
central nervous system developmentGO:00074171230.018
regulation of gtp catabolic processGO:00331241800.018
negative regulation of cell adhesionGO:0007162640.018
spermatid differentiationGO:004851540.018
negative regulation of phosphatase activityGO:0010923610.018
pericardium developmentGO:006003920.018
negative regulation of protein transportGO:0051224750.018
positive regulation of leukocyte differentiationGO:1902107370.018
regulation of protein stabilityGO:0031647870.018
muscle cell differentiationGO:0042692630.018
epithelial cell proliferationGO:00506731280.018
brain developmentGO:0007420970.018
establishment of protein localization to organelleGO:00725941720.018
regulation of cell projection organizationGO:00313441070.018
nucleoside monophosphate metabolic processGO:00091231910.017
regulation of cell growthGO:00015581350.017
guanosine containing compound metabolic processGO:19010682440.017
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.017
positive regulation of cell deathGO:00109422630.017
regulation of dephosphorylationGO:0035303960.017
branching involved in salivary gland morphogenesisGO:006044510.017
cellular response to organic cyclic compoundGO:00714071270.017
limb bud formationGO:006017410.017
protein oligomerizationGO:00512591730.017
lymphocyte activationGO:00466491330.017
positive regulation of cell adhesionGO:0045785840.017
stem cell developmentGO:0048864690.017
monocarboxylic acid metabolic processGO:00327871850.017
nucleocytoplasmic transportGO:00069131760.017
positive regulation of organelle organizationGO:00106381950.017
cellular response to organonitrogen compoundGO:00714171240.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
positive regulation of neural precursor cell proliferationGO:200017920.017
cellular component disassemblyGO:0022411920.017
sensory perception of chemical stimulusGO:0007606380.017
regulation of phosphatase activityGO:0010921810.017
peptidyl tyrosine modificationGO:00182121700.017
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.017
cardiac muscle cell contractionGO:008600340.017
cell chemotaxisGO:00603261120.017
positive regulation of kinase activityGO:00336742040.017
hindbrain developmentGO:003090230.017
negative regulation of blood vessel morphogenesisGO:2000181410.016
mitotic sister chromatid segregationGO:0000070530.016
organic acid biosynthetic processGO:0016053970.016
tube morphogenesisGO:0035239950.016
inflammatory responseGO:0006954790.016
regulation of rho gtpase activityGO:0032319660.016
myeloid leukocyte differentiationGO:0002573600.016
regulation of nucleotide catabolic processGO:00308112050.016
regulation of immune effector processGO:0002697910.016
regulation of leukocyte differentiationGO:1902105610.016
negative regulation of intracellular transportGO:0032387600.016
neurogenesisGO:00220081690.016
sensory perceptionGO:00076001030.016
circadian behaviorGO:004851220.016
regulation of nucleocytoplasmic transportGO:0046822980.016
cellular macromolecule catabolic processGO:00442653800.016
regulation of growthGO:00400081650.016
detection of mechanical stimulus involved in sensory perceptionGO:005097410.016
regulation of protein targetingGO:1903533910.016
regulation of protein localization to nucleusGO:1900180850.016
basement membrane organizationGO:007171130.016
positive regulation of cell activationGO:0050867810.016
actomyosin structure organizationGO:0031032590.016
positive regulation of nucleoside metabolic processGO:00459791860.016
cellular response to nitrogen compoundGO:19016991440.016
immune effector processGO:00022521590.016
cellular lipid metabolic processGO:00442553030.015
regulation of neural precursor cell proliferationGO:200017740.015
striated muscle tissue developmentGO:0014706590.015
extracellular matrix organizationGO:0030198410.015
negative regulation of protein maturationGO:19033181420.015
glycoprotein biosynthetic processGO:0009101910.015
response to molecule of bacterial originGO:0002237820.015
cell cell junction organizationGO:0045216690.015
negative regulation of anion channel activityGO:001036010.015
regulation of multi organism processGO:00439001570.015
receptor metabolic processGO:0043112810.015
positive regulation of cell developmentGO:0010720920.015
regulation of apoptotic signaling pathwayGO:20012331750.015
response to oxidative stressGO:00069791210.015
regulation of cellular response to stressGO:00801352440.015
negative regulation of protein modification processGO:00314002000.015
cell projection assemblyGO:00300311260.015
response to drugGO:0042493810.015
embryonic epithelial tube formationGO:000183840.015
carboxylic acid biosynthetic processGO:0046394970.015
cyclic nucleotide metabolic processGO:0009187820.015
patterning of blood vesselsGO:000156920.015
reproductive processGO:00224141060.015
skeletal system developmentGO:0001501790.015
spermatid developmentGO:000728640.015
associative learningGO:000830610.015
mesenchymal cell differentiationGO:0048762520.015
negative regulation of gastrulationGO:200054240.015
divalent metal ion transportGO:00708381520.015
syncytium formation by plasma membrane fusionGO:000076820.015
meiotic chromosome segregationGO:004513240.015
response to light stimulusGO:0009416870.015
negative regulation of angiogenesisGO:0016525390.014
cellular protein complex assemblyGO:00436231880.014
regulation of protein catabolic processGO:00421761550.014
developmental programmed cell deathGO:001062330.014
positive regulation of gtpase activityGO:00435471660.014
calcium ion transportGO:00068161470.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.014
regulation of mapk cascadeGO:00434082620.014
rhodopsin mediated signaling pathwayGO:001605610.014
neural crest cell migrationGO:000175520.014
response to bacteriumGO:00096171440.014
reactive oxygen species biosynthetic processGO:190340940.014
cellular response to abiotic stimulusGO:00712141170.014

PRSS23 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.151
connective tissue diseaseDOID:651090.054
sensory system diseaseDOID:00501552030.035
nervous system diseaseDOID:8634310.035
bone diseaseDOID:0080001880.028
disease of metabolismDOID:00146672950.026
cancerDOID:1621670.026
disease of cellular proliferationDOID:145661740.026
auditory system diseaseDOID:2742530.021
organ system cancerDOID:00506861640.021
central nervous system diseaseDOID:3311860.020
cardiovascular system diseaseDOID:12871060.017
muscular diseaseDOID:00800001140.016
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016
neurodegenerative diseaseDOID:12891020.016
nonsyndromic deafnessDOID:0050563500.015
autosomal dominant nonsyndromic deafnessDOID:0050564230.015
muscle tissue diseaseDOID:661130.014