Homo sapiens

0 known processes

RRM2B

ribonucleotide reductase M2 B (TP53 inducible)

(Aliases: P53R2,DKFZp686M05248,MTDPS8A,MGC102856,MTDPS8B,MGC42116)

RRM2B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine nucleoside triphosphate catabolic processGO:00091463920.174
post embryonic developmentGO:000979120.162
locomotory behaviorGO:000762610.134
cytoplasmic transportGO:00164823790.107
small gtpase mediated signal transductionGO:0007264780.090
modification dependent macromolecule catabolic processGO:00436322120.090
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.090
cellular macromolecule catabolic processGO:00442653800.082
regulation of cell cycleGO:00517263930.080
vesicle mediated transportGO:00161923710.080
oxidation reduction processGO:00551143960.080
Yeast Mouse
ras protein signal transductionGO:0007265730.079
glycosyl compound catabolic processGO:19016584130.077
adult locomotory behaviorGO:000834410.075
purine nucleotide catabolic processGO:00061954050.074
proteolysis involved in cellular protein catabolic processGO:00516032440.073
purine ribonucleoside catabolic processGO:00461303980.073
protein oligomerizationGO:00512591730.072
purine ribonucleotide catabolic processGO:00091544040.071
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.071
regulation of proteolysisGO:00301622930.071
organophosphate catabolic processGO:00464344300.070
protein catabolic processGO:00301633250.069
purine nucleoside triphosphate metabolic processGO:00091444120.068
cellular protein catabolic processGO:00442572610.068
nucleoside phosphate catabolic processGO:19012924120.068
purine ribonucleoside metabolic processGO:00461284370.067
positive regulation of cell deathGO:00109422630.067
purine containing compound catabolic processGO:00725234110.065
ubiquitin dependent protein catabolic processGO:00065112060.064
protein localization to organelleGO:00333652800.063
intracellular protein transportGO:00068862700.063
mapk cascadeGO:00001652880.063
positive regulation of programmed cell deathGO:00430682490.062
mitotic cell cycleGO:00002783260.062
nucleoside triphosphate catabolic processGO:00091433940.060
multicellular organismal agingGO:001025930.059
ribonucleoside triphosphate metabolic processGO:00091994120.058
ribonucleoside triphosphate catabolic processGO:00092033910.057
negative regulation of cell deathGO:00605483450.056
Mouse
proteasomal protein catabolic processGO:00104981760.055
positive regulation of hydrolase activityGO:00513453310.055
single organism cellular localizationGO:19025803320.054
purine nucleoside catabolic processGO:00061523980.054
modification dependent protein catabolic processGO:00199412090.054
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.054
posttranscriptional regulation of gene expressionGO:00106082130.053
rho protein signal transductionGO:0007266260.052
endomembrane system organizationGO:00102561960.052
positive regulation of apoptotic processGO:00430652460.052
chemical homeostasisGO:00488783060.050
purine ribonucleoside triphosphate metabolic processGO:00092054110.050
nucleoside triphosphate metabolic processGO:00091414220.049
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073910.049
negative regulation of programmed cell deathGO:00430693210.049
Mouse
signal transduction by phosphorylationGO:00230142970.048
dephosphorylationGO:00163112090.047
positive regulation of nucleotide metabolic processGO:00459812300.047
regulation of response to external stimulusGO:00321012220.046
positive regulation of cellular catabolic processGO:00313312840.045
guanosine containing compound metabolic processGO:19010682440.045
ribonucleotide catabolic processGO:00092614050.045
positive regulation of catabolic processGO:00098963100.044
determination of adult lifespanGO:000834020.043
cation transportGO:00068123310.043
response to abiotic stimulusGO:00096283360.043
mitochondrion organizationGO:00070051560.042
Mouse
metal ion transportGO:00300012720.042
ribonucleoside catabolic processGO:00424544060.042
regulation of mitotic cell cycleGO:00073461890.041
zymogen activationGO:0031638700.041
mitotic cell cycle processGO:19030472860.041
nucleoside catabolic processGO:00091644080.041
regulation of nucleoside metabolic processGO:00091182090.040
response to biotic stimulusGO:00096072760.040
neuromuscular junction developmentGO:000752830.040
positive regulation of phosphorylationGO:00423273940.040
protein modification by small protein conjugationGO:00324463420.039
negative regulation of apoptotic processGO:00430663160.039
Mouse
positive regulation of proteolysisGO:00458621420.039
system processGO:00030083490.038
Mouse
carbohydrate derivative biosynthetic processGO:19011372070.038
Yeast Mouse
mitotic cell cycle phase transitionGO:00447721620.038
regulation of kinase activityGO:00435493140.037
apoptotic signaling pathwayGO:00971902680.037
Mouse
protein heterotetramerizationGO:005129030.036
protein processingGO:00164852260.036
positive regulation of nucleoside metabolic processGO:00459791860.035
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.035
response to external biotic stimulusGO:00432072610.035
regulation of wnt signaling pathwayGO:00301111230.035
regulation of purine nucleotide catabolic processGO:00331212050.035
regulation of endopeptidase activityGO:00525481700.035
nucleotide catabolic processGO:00091664080.034
guanosine containing compound catabolic processGO:19010692390.034
immune effector processGO:00022521590.034
regulation of cytoplasmic transportGO:19036491490.033
regulation of purine nucleotide metabolic processGO:19005422640.033
regulation of protein localizationGO:00328802960.033
protein ubiquitinationGO:00165673140.033
response to bacteriumGO:00096171440.033
ion transmembrane transportGO:00342203380.033
positive regulation of mapk cascadeGO:00434101900.032
positive regulation of cysteine type endopeptidase activityGO:2001056790.032
cell cycle phase transitionGO:00447701730.031
positive regulation of nucleotide catabolic processGO:00308131850.031
calcium ion transportGO:00068161470.031
protein localization to nucleusGO:00345041360.031
regulation of defense responseGO:00313471540.031
negative regulation of phosphate metabolic processGO:00459362670.031
defense response to other organismGO:00985421290.031
stress activated protein kinase signaling cascadeGO:0031098940.030
negative regulation of cellular protein metabolic processGO:00322693530.030
organelle assemblyGO:00709251760.030
response to oxygen containing compoundGO:19017003690.030
response to other organismGO:00517072610.030
ribonucleoside monophosphate metabolic processGO:00091611870.029
negative regulation of catalytic activityGO:00430863350.029
defense responseGO:00069523150.029
regulation of cell cycle processGO:00105642660.029
regulation of cellular component biogenesisGO:00440872810.029
regulation of peptidase activityGO:00525471800.029
regulation of cysteine type endopeptidase activityGO:20001161270.028
cellular homeostasisGO:00197251960.028
autophagyGO:0006914880.028
protein maturationGO:00516042330.028
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.027
membrane organizationGO:00610242920.027
i kappab kinase nf kappab signalingGO:00072491660.027
regulation of protein kinase activityGO:00458592890.027
gtp catabolic processGO:00061842370.027
cation homeostasisGO:00550801890.027
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.027
regulation of sequence specific dna binding transcription factor activityGO:00510902110.026
lipid biosynthetic processGO:00086101770.026
regulation of nucleotide catabolic processGO:00308112050.026
regulation of gtpase activityGO:00430871800.026
protein stabilizationGO:0050821640.026
nucleoside phosphate biosynthetic processGO:19012931090.026
Yeast Mouse
positive regulation of purine nucleotide metabolic processGO:19005442270.026
nuclear transportGO:00511691790.026
cellular ketone metabolic processGO:0042180800.025
cation transmembrane transportGO:00986552380.025
divalent inorganic cation homeostasisGO:00725071360.025
gtp metabolic processGO:00460392390.025
cytokine productionGO:00018162470.025
negative regulation of phosphorus metabolic processGO:00105632670.025
single organism membrane organizationGO:00448022680.025
regulation of cellular amino acid metabolic processGO:000652160.025
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.025
positive regulation of cellular amine metabolic processGO:003324070.025
cellular amino acid metabolic processGO:00065201160.025
protein targetingGO:00066051870.025
positive regulation of protein phosphorylationGO:00019343130.025
negative regulation of cell proliferationGO:00082852280.025
wnt signaling pathwayGO:00160551560.024
cellular amine metabolic processGO:0044106410.024
actin filament based processGO:00300292240.024
regulation of intracellular transportGO:00323861950.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
positive regulation of ras gtpase activityGO:00323201170.024
protein autophosphorylationGO:00467771230.024
cellular macromolecular complex assemblyGO:00346223240.024
negative regulation of protein phosphorylationGO:00019331400.024
cellular response to dna damage stimulusGO:00069743790.023
Mouse
regulation of transferase activityGO:00513383550.023
protein importGO:00170381300.023
lipid metabolic processGO:00066293810.023
receptor metabolic processGO:0043112810.023
dna repairGO:00062811980.023
Mouse
establishment of protein localization to organelleGO:00725941720.023
positive regulation of cellular component biogenesisGO:00440891580.023
protein dephosphorylationGO:0006470810.023
single organism nuclear importGO:19025931040.023
activation of cysteine type endopeptidase activityGO:0097202570.022
amine metabolic processGO:0009308440.022
negative regulation of cell cycle processGO:00109481210.022
regulation of protein transportGO:00512232130.022
cellular lipid metabolic processGO:00442553030.022
regulation of establishment of protein localizationGO:00702012420.022
negative regulation of cell cycle phase transitionGO:1901988890.022
nucleocytoplasmic transportGO:00069131760.022
negative regulation of protein metabolic processGO:00512483910.022
regenerationGO:003109940.022
negative regulation of cell cycleGO:00457861930.022
negative regulation of protein modification processGO:00314002000.021
regulation of protein localization to nucleusGO:1900180850.021
memoryGO:000761330.021
immune responseGO:00069553070.021
taxisGO:00423301570.021
regulation of protein stabilityGO:0031647870.021
enzyme linked receptor protein signaling pathwayGO:00071673030.021
organophosphate biosynthetic processGO:00904071630.021
Yeast Mouse
regulation of protein catabolic processGO:00421761550.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.021
response to fungusGO:000962040.021
apoptotic mitochondrial changesGO:0008637570.021
positive regulation of immune responseGO:00507781590.021
regulation of stress activated protein kinase signaling cascadeGO:0070302850.021
positive regulation of purine nucleotide catabolic processGO:00331231850.020
positive regulation of gtp catabolic processGO:00331261660.020
regulation of small gtpase mediated signal transductionGO:00510561560.020
behaviorGO:00076101120.020
negative regulation of phosphorylationGO:00423261740.020
regulation of innate immune responseGO:0045088970.020
nucleotide biosynthetic processGO:00091651090.020
Yeast Mouse
secretion by cellGO:00329402260.020
regulation of intracellular protein transportGO:00331571230.020
segmentationGO:003528240.020
protein import into nucleusGO:00066061040.019
endosomal transportGO:00161971290.019
single organism carbohydrate metabolic processGO:00447231930.019
regulation of ras protein signal transductionGO:00465781550.019
positive regulation of transportGO:00510503360.019
negative regulation of apoptotic signaling pathwayGO:2001234970.019
Mouse
regulation of actin cytoskeleton organizationGO:00329561160.019
negative regulation of multicellular organismal processGO:00512413170.019
maintenance of locationGO:00512351120.019
endocytosisGO:00068971590.019
positive regulation of cell cycleGO:00457871400.019
negative regulation of cellular component organizationGO:00511292350.019
cell substrate adhesionGO:00315891320.019
ribonucleoside monophosphate catabolic processGO:00091581580.018
positive regulation of cellular component organizationGO:00511303760.018
response to virusGO:00096151260.018
actin filament organizationGO:00070151280.018
negative regulation of transferase activityGO:00513481240.018
regulation of i kappab kinase nf kappab signalingGO:00431221620.018
regulation of nucleotide metabolic processGO:00061402690.018
negative regulation of transportGO:00510511760.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
positive regulation of peptidase activityGO:0010952880.018
growthGO:00400072020.018
glycerolipid metabolic processGO:00464861070.018
protein deubiquitinationGO:0016579790.018
divalent metal ion transportGO:00708381520.018
atp catabolic processGO:00062001570.018
divalent inorganic cation transportGO:00725111580.018
positive regulation of endopeptidase activityGO:0010950840.018
secretionGO:00469032540.018
microtubule based processGO:00070172100.018
ion homeostasisGO:00508012300.018
nucleoside monophosphate catabolic processGO:00091251590.017
calcium ion transmembrane transportGO:0070588760.017
cellular response to endogenous stimulusGO:00714953360.017
cell divisionGO:00513011680.017
positive regulation of defense responseGO:0031349870.017
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.017
regulation of cellular amine metabolic processGO:0033238110.017
positive regulation of cellular protein catabolic processGO:1903364370.017
protein targeting to nucleusGO:00447441040.017
regulation of gtp catabolic processGO:00331241800.017
negative regulation of kinase activityGO:00336731060.017
regulation of immune effector processGO:0002697910.017
negative regulation of intracellular signal transductionGO:19025321830.017
Mouse
regulation of cellular protein catabolic processGO:1903362960.017
cellular response to oxygen containing compoundGO:19017012760.017
cellular component morphogenesisGO:00329893140.017
positive regulation of cell differentiationGO:00455972110.017
metal ion homeostasisGO:00550651690.016
calcium ion homeostasisGO:00550741220.016
cell adhesionGO:00071553250.016
atp metabolic processGO:00460341760.016
response to growth factorGO:00708482050.016
intrinsic apoptotic signaling pathwayGO:00971931270.016
Mouse
biological adhesionGO:00226103310.016
plasma membrane organizationGO:00070091150.016
positive regulation of secretionGO:00510471160.016
neurological system processGO:00508771630.016
activation of innate immune responseGO:0002218550.016
glycerophospholipid metabolic processGO:0006650840.015
cellular carbohydrate metabolic processGO:0044262840.015
regulation of secretion by cellGO:19035301770.015
cell matrix adhesionGO:0007160850.015
regulation of nucleocytoplasmic transportGO:0046822980.015
rna processingGO:00063962550.015
positive regulation of gtpase activityGO:00435471660.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
regulation of dna metabolic processGO:00510521530.015
regulation of cell adhesionGO:00301551660.015
regulation of ras gtpase activityGO:00323181280.015
transmembrane transportGO:00550853990.015
regulation of immune responseGO:00507762010.015
cell morphogenesisGO:00009022960.015
regulation of cellular response to stressGO:00801352440.015
innate immune responseGO:00450871780.014
ncrna metabolic processGO:00346601080.014
g1 s transition of mitotic cell cycleGO:0000082780.014
regulation of locomotionGO:00400123290.014
erk1 and erk2 cascadeGO:00703711040.014
regulation of cytoskeleton organizationGO:00514931770.014
oogenesisGO:004847720.014
cellular cation homeostasisGO:00300031630.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
inner ear morphogenesisGO:004247240.014
rhythmic behaviorGO:000762220.014
regulation of cellular ketone metabolic processGO:0010565500.014
positive regulation of cell proliferationGO:00082843010.014
steroid metabolic processGO:0008202940.014
negative regulation of protein kinase activityGO:0006469980.014
cell cycle g1 s phase transitionGO:0044843800.014
regulation of multi organism processGO:00439001570.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
spermatid differentiationGO:004851540.014
peptidyl serine phosphorylationGO:00181051010.013
regulation of response to biotic stimulusGO:0002831550.013
regulation of cell differentiationGO:00455953930.013
positive regulation of wnt signaling pathwayGO:0030177540.013
inorganic ion transmembrane transportGO:00986602310.013
cellular response to external stimulusGO:00714961110.013
negative regulation of multi organism processGO:0043901920.013
protein modification by small protein removalGO:0070646920.013
regulation of vesicle mediated transportGO:00606271300.013
glycerolipid biosynthetic processGO:0045017510.013
vesicle organizationGO:0016050620.013
regulation of protein targetingGO:1903533910.013
maintenance of protein locationGO:0045185570.013
negative regulation of mitotic cell cycle phase transitionGO:1901991850.013
response to oxidative stressGO:00069791210.013
Mouse
ncrna processingGO:0034470830.013
immune response activating signal transductionGO:0002757900.013
single organismal cell cell adhesionGO:00163371480.013
negative regulation of smoothened signaling pathwayGO:004587930.013
regulation of cellular component movementGO:00512703340.013
reactive oxygen species biosynthetic processGO:190340940.013
membrane buddingGO:0006900280.013
anterior posterior axis specificationGO:000994820.013
regulation of growthGO:00400081650.013
positive regulation of synaptic transmissionGO:005080640.012
regulation of growth rateGO:004000910.012
regulation of secretionGO:00510461940.012
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.012
response to nitrogen compoundGO:19016981840.012
regulation of actin filament based processGO:00329701410.012
endosome to lysosome transportGO:0008333210.012
cardiovascular system developmentGO:00723582620.012
stress activated mapk cascadeGO:0051403930.012
g2 m transition of mitotic cell cycleGO:0000086410.012
cell growthGO:00160491600.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
cellular protein complex assemblyGO:00436231880.012
organ formationGO:004864530.012
negative regulation of catabolic processGO:00098951040.012
single organism cell adhesionGO:00986021790.012
cell type specific apoptotic processGO:00972851250.012
axis elongationGO:000340140.012
regulation of mapk cascadeGO:00434082620.012
positive regulation of organelle organizationGO:00106381950.012
immune response regulating signaling pathwayGO:0002764970.012
negative regulation of mitotic cell cycleGO:00459301020.012
regulation of protein serine threonine kinase activityGO:00719001790.012
circadian behaviorGO:004851220.012
actin cytoskeleton organizationGO:00300362070.012
negative regulation of synaptic transmissionGO:005080520.012
female gamete generationGO:000729220.012
cellular chemical homeostasisGO:00550821800.012
defense response to fungusGO:005083240.012
lysosomal transportGO:0007041330.012
establishment of protein localization to membraneGO:00901501210.012
transforming growth factor beta receptor signaling pathwayGO:0007179760.012
cellular response to extracellular stimulusGO:0031668720.012
regulation of hormone levelsGO:00108171250.012
viral processGO:00160321460.012
brain developmentGO:0007420970.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
viral life cycleGO:00190581320.012
peptidyl tyrosine modificationGO:00182121700.012
cell cycle g2 m phase transitionGO:0044839430.012
bud outgrowth involved in lung branchingGO:006044710.012
nitrogen compound transportGO:00717051910.012
epithelial tube branching involved in lung morphogenesisGO:006044140.011
regulation of ion transportGO:00432691890.011
meiotic chromosome segregationGO:004513240.011
protein localization to plasma membraneGO:0072659930.011
regulation of protein complex assemblyGO:00432541470.011
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.011
Mouse
lipid localizationGO:00108761060.011
blastoderm segmentationGO:000735020.011
protein polyubiquitinationGO:00002091100.011
positive regulation of innate immune responseGO:0045089790.011
developmental programmed cell deathGO:001062330.011
positive regulation of protein transportGO:00512221350.011
regulation of neural precursor cell proliferationGO:200017740.011
jnk cascadeGO:0007254800.011
reactive nitrogen species metabolic processGO:200105730.011
monovalent inorganic cation transportGO:00156721280.011
carbohydrate metabolic processGO:00059752070.011
negative regulation of protein transportGO:0051224750.011
mitotic g1 dna damage checkpointGO:0031571170.011
extrinsic apoptotic signaling pathwayGO:00971911190.011
associative learningGO:000830610.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
regulation of stress activated mapk cascadeGO:0032872840.011
photoreceptor cell differentiationGO:004653020.011
g1 dna damage checkpointGO:0044783180.011
macroautophagyGO:0016236390.011
peptidyl tyrosine phosphorylationGO:00181081700.011
positive regulation of cell migrationGO:00303351720.011
translationGO:00064121320.011
monosaccharide metabolic processGO:0005996740.011
negative regulation of cellular catabolic processGO:0031330830.011
sequestering of calcium ionGO:0051208170.011
inorganic cation transmembrane transportGO:00986621940.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.011
sensory perception of smellGO:000760820.011
myeloid cell differentiationGO:00300991170.011
lipoprotein metabolic processGO:0042157420.011
regulation of protein import into nucleusGO:0042306780.011
positive regulation of developmental processGO:00510943140.011
vacuole organizationGO:0007033440.011
response to hypoxiaGO:0001666960.011
positive regulation of response to external stimulusGO:0032103880.011
protein localization to membraneGO:00726571600.011
inflammatory responseGO:0006954790.011
interspecies interaction between organismsGO:00444191560.011
actin filament bundle assemblyGO:0051017540.010
epithelial cell proliferationGO:00506731280.010
cell substrate adherens junction assemblyGO:0007045300.010
regulation of proteasomal protein catabolic processGO:0061136870.010
peptidyl threonine dephosphorylationGO:003597070.010
lens development in camera type eyeGO:000208820.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.010
ventral spinal cord developmentGO:002151710.010
phosphatidylinositol metabolic processGO:0046488530.010
positive regulation of protein catabolic processGO:0045732750.010
hindbrain developmentGO:003090230.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.010
multi organism cellular processGO:00447641560.010
regulation of cell growthGO:00015581350.010
cellular ion homeostasisGO:00068731680.010
tissue migrationGO:00901301190.010
cellular response to cytokine stimulusGO:00713451810.010
compound eye developmentGO:004874910.010
mitotic cell cycle checkpointGO:0007093680.010
response to cytokineGO:00340972320.010

RRM2B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.059
disease of cellular proliferationDOID:145661740.059
cancerDOID:1621670.059
disease of metabolismDOID:00146672950.027
musculoskeletal system diseaseDOID:172230.024
immune system diseaseDOID:29141550.023
hematopoietic system diseaseDOID:741000.023
thoracic cancerDOID:5093210.017
breast cancerDOID:1612210.017
sensory system diseaseDOID:00501552030.016
nervous system diseaseDOID:8634310.016
eye diseaseDOID:56141490.015
retinal diseaseDOID:56791180.015
eye and adnexa diseaseDOID:14921500.015
connective tissue diseaseDOID:651090.014
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
retinal degenerationDOID:8466890.012
inherited metabolic disorderDOID:6552420.011
anemiaDOID:2355550.011
central nervous system diseaseDOID:3311860.010