Homo sapiens

61 known processes

BRE

brain and reproductive organ-expressed (TNFRSF1A modulator)

(Aliases: BRCC45,BRCC4)

BRE biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of dna repairGO:0045739250.888
positive regulation of response to dna damage stimulusGO:2001022430.800
protein deubiquitinationGO:0016579790.749
protein k63 linked deubiquitinationGO:0070536210.728
double strand break repairGO:00063021010.602
g2 dna damage checkpointGO:0031572260.572
cellular response to dna damage stimulusGO:00069743790.563
dna repairGO:00062811980.538
positive regulation of dna metabolic processGO:0051054730.450
response to ionizing radiationGO:0010212650.438
dna damage checkpointGO:0000077680.432
cell cycle checkpointGO:00000751170.411
response to abiotic stimulusGO:00096283360.391
regulation of cellular response to stressGO:00801352440.390
regulation of dna repairGO:0006282470.390
protein modification by small protein removalGO:0070646920.389
response to radiationGO:00093141510.339
dna integrity checkpointGO:0031570710.326
nadph oxidationGO:007099530.275
regulation of response to dna damage stimulusGO:2001020940.260
histone deubiquitinationGO:0016578160.245
covalent chromatin modificationGO:00165692540.114
chromatin modificationGO:00165682980.096
chromatin organizationGO:00063253510.096
regulation of dna metabolic processGO:00510521530.096
coenzyme metabolic processGO:0006732650.093
purine nucleoside triphosphate metabolic processGO:00091444120.093
oxidation reduction processGO:00551143960.089
purine ribonucleoside catabolic processGO:00461303980.078
cellular amino acid metabolic processGO:00065201160.073
purine ribonucleoside metabolic processGO:00461284370.066
amine metabolic processGO:0009308440.062
regulation of cellular amino acid metabolic processGO:000652160.061
ribonucleoside monophosphate metabolic processGO:00091611870.060
negative regulation of protein metabolic processGO:00512483910.057
regulation of cellular amine metabolic processGO:0033238110.055
mitochondrion organizationGO:00070051560.055
purine ribonucleoside monophosphate metabolic processGO:00091671860.053
negative regulation of protein processingGO:00109551420.051
nucleoside monophosphate metabolic processGO:00091231910.049
organophosphate catabolic processGO:00464344300.049
nucleoside phosphate catabolic processGO:19012924120.048
cellular ketone metabolic processGO:0042180800.048
ribonucleoside triphosphate metabolic processGO:00091994120.048
histone modificationGO:00165702510.047
ribonucleoside catabolic processGO:00424544060.047
protein catabolic processGO:00301633250.047
modification dependent macromolecule catabolic processGO:00436322120.045
positive regulation of cellular amino acid metabolic processGO:004576430.042
protein processingGO:00164852260.041
positive regulation of cellular amine metabolic processGO:003324070.040
purine nucleotide catabolic processGO:00061954050.040
ribonucleoside triphosphate catabolic processGO:00092033910.040
female gamete generationGO:000729220.039
protein maturationGO:00516042330.039
multicellular organismal agingGO:001025930.039
cellular macromolecule catabolic processGO:00442653800.038
small gtpase mediated signal transductionGO:0007264780.037
cytoplasmic transportGO:00164823790.037
nucleoside catabolic processGO:00091644080.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
nucleoside triphosphate metabolic processGO:00091414220.036
ion homeostasisGO:00508012300.035
locomotory behaviorGO:000762610.034
regulation of proteasomal protein catabolic processGO:0061136870.034
purine nucleoside triphosphate catabolic processGO:00091463920.034
regulation of protein processingGO:00706131500.034
actin filament based processGO:00300292240.033
cellular protein catabolic processGO:00442572610.033
cellular amine metabolic processGO:0044106410.032
regulation of purine nucleotide metabolic processGO:19005422640.032
response to woundingGO:00096111680.032
carbohydrate derivative biosynthetic processGO:19011372070.032
atp metabolic processGO:00460341760.031
proteolysis involved in cellular protein catabolic processGO:00516032440.031
cell divisionGO:00513011680.031
negative regulation of transportGO:00510511760.031
transmembrane transportGO:00550853990.030
negative regulation of catalytic activityGO:00430863350.030
positive regulation of purine nucleotide metabolic processGO:19005442270.030
glycosyl compound catabolic processGO:19016584130.029
regulation of cellular ketone metabolic processGO:0010565500.029
regenerationGO:003109940.029
oogenesisGO:004847720.029
carboxylic acid catabolic processGO:0046395710.029
wound healingGO:00420601150.029
organonitrogen compound biosynthetic processGO:19015662000.028
nucleotide catabolic processGO:00091664080.028
post embryonic developmentGO:000979120.028
purine ribonucleotide catabolic processGO:00091544040.028
endosomal transportGO:00161971290.028
positive regulation of transportGO:00510503360.028
regulation of protein maturationGO:19033171500.028
ribonucleotide catabolic processGO:00092614050.028
regulation of nucleotide metabolic processGO:00061402690.028
reactive nitrogen species metabolic processGO:200105730.027
positive regulation of catabolic processGO:00098963100.026
metal ion homeostasisGO:00550651690.026
negative regulation of cellular protein metabolic processGO:00322693530.026
protein oligomerizationGO:00512591730.026
positive regulation of phosphorylationGO:00423273940.026
carbohydrate metabolic processGO:00059752070.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
dicarboxylic acid metabolic processGO:0043648290.025
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.025
negative regulation of catabolic processGO:00098951040.025
single organism carbohydrate metabolic processGO:00447231930.025
regulation of nucleoside metabolic processGO:00091182090.025
negative regulation of protein modification processGO:00314002000.025
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.024
regulation of nucleotide catabolic processGO:00308112050.024
negative regulation of programmed cell deathGO:00430693210.024
tissue regenerationGO:004224630.024
regulation of proteolysisGO:00301622930.024
innate immune responseGO:00450871780.024
lipid metabolic processGO:00066293810.023
cellular ion homeostasisGO:00068731680.023
proteasomal protein catabolic processGO:00104981760.023
regulation of defense responseGO:00313471540.023
purine containing compound biosynthetic processGO:0072522880.023
purine nucleoside monophosphate metabolic processGO:00091261860.023
small molecule catabolic processGO:0044282920.023
oocyte differentiationGO:000999420.023
response to oxidative stressGO:00069791210.022
regulation of protein localizationGO:00328802960.022
cellular modified amino acid metabolic processGO:0006575640.022
cytokinesisGO:0000910960.022
defense responseGO:00069523150.022
interspecies interaction between organismsGO:00444191560.021
determination of adult lifespanGO:000834020.021
purine containing compound catabolic processGO:00725234110.021
regulation of cell cycle processGO:00105642660.021
regulation of small gtpase mediated signal transductionGO:00510561560.020
tricarboxylic acid metabolic processGO:007235040.020
regulation of immune responseGO:00507762010.020
regulation of establishment of protein localizationGO:00702012420.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
positive regulation of cellular catabolic processGO:00313312840.020
regulation of intracellular transportGO:00323861950.019
cation transportGO:00068123310.019
regulation of cellular component biogenesisGO:00440872810.019
generation of precursor metabolites and energyGO:0006091680.019
regulation of ras protein signal transductionGO:00465781550.019
cellular lipid metabolic processGO:00442553030.019
negative regulation of multicellular organismal processGO:00512413170.019
protein modification by small protein conjugationGO:00324463420.019
macromolecule glycosylationGO:0043413630.019
alpha amino acid metabolic processGO:1901605720.018
establishment or maintenance of bipolar cell polarityGO:006124520.018
viral processGO:00160321460.018
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.018
neuromuscular junction developmentGO:000752830.018
negative regulation of apoptotic processGO:00430663160.018
organic acid catabolic processGO:0016054710.018
citrate metabolic processGO:000610120.018
negative regulation of cellular catabolic processGO:0031330830.018
positive regulation of nucleotide metabolic processGO:00459812300.018
nitrogen compound transportGO:00717051910.018
cofactor metabolic processGO:0051186870.018
metal ion transportGO:00300012720.017
negative regulation of protein catabolic processGO:0042177590.017
negative regulation of cellular component organizationGO:00511292350.017
associative learningGO:000830610.017
positive regulation of nucleoside metabolic processGO:00459791860.017
nucleoside triphosphate catabolic processGO:00091433940.017
regulation of protein complex assemblyGO:00432541470.017
positive regulation of hydrolase activityGO:00513453310.017
guanosine containing compound metabolic processGO:19010682440.017
ion transmembrane transportGO:00342203380.017
oocyte developmentGO:004859910.017
small molecule biosynthetic processGO:00442831570.017
positive regulation of nucleotide catabolic processGO:00308131850.016
negative regulation of cell proliferationGO:00082852280.016
regulation of cytoplasmic transportGO:19036491490.016
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation of gtpase activityGO:00435471660.016
response to inorganic substanceGO:00100351270.016
calcium ion transportGO:00068161470.016
cation transmembrane transportGO:00986552380.016
positive regulation of protein phosphorylationGO:00019343130.016
regulation of peptidase activityGO:00525471800.016
guanosine containing compound catabolic processGO:19010692390.016
viral life cycleGO:00190581320.016
regulation of gtp catabolic processGO:00331241800.016
adult locomotory behaviorGO:000834410.016
modification dependent protein catabolic processGO:00199412090.016
response to cytokineGO:00340972320.016
negative regulation of peptidase activityGO:0010466910.016
immune effector processGO:00022521590.016
ketone catabolic processGO:004218230.016
protein localization to organelleGO:00333652800.015
regulation of protein kinase activityGO:00458592890.015
positive regulation of secretion by cellGO:19035321080.015
vitamin metabolic processGO:0006766260.015
positive regulation of cellular component organizationGO:00511303760.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of cellular component movementGO:00512703340.015
protein glycosylationGO:0006486620.015
positive regulation of apoptotic processGO:00430652460.015
gtp catabolic processGO:00061842370.015
negative regulation of proteolysisGO:00458611320.015
spermatid differentiationGO:004851540.015
biological adhesionGO:00226103310.015
regulation of cell cycleGO:00517263930.015
glycoprotein metabolic processGO:00091001100.015
segmentationGO:003528240.015
regulation of locomotionGO:00400123290.015
ras protein signal transductionGO:0007265730.015
memoryGO:000761330.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
cellular amino acid catabolic processGO:0009063310.015
regulation of protein transportGO:00512232130.015
regulation of transmembrane transporter activityGO:0022898740.015
regulation of secretionGO:00510461940.015
mitochondrial transportGO:0006839600.015
actin mediated cell contractionGO:0070252120.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
divalent inorganic cation transportGO:00725111580.014
visual behaviorGO:000763220.014
purine nucleotide biosynthetic processGO:0006164840.014
cardiac muscle cell contractionGO:008600340.014
cytokine productionGO:00018162470.014
positive regulation of cytokine productionGO:00018191670.014
regulation of secretion by cellGO:19035301770.014
cell cell signalingGO:00072671550.014
positive regulation of gtp catabolic processGO:00331261660.014
organic hydroxy compound metabolic processGO:19016151470.014
growthGO:00400072020.014
spermatid developmentGO:000728640.014
negative regulation of growthGO:0045926970.014
nervous system developmentGO:00073992930.014
gtp metabolic processGO:00460392390.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
negative regulation of endopeptidase activityGO:0010951840.013
regulation of synaptic plasticityGO:004816730.013
protein acylationGO:00435431380.013
positive regulation of cellular component biogenesisGO:00440891580.013
negative regulation of cellular protein catabolic processGO:1903363380.013
atp catabolic processGO:00062001570.013
rho protein signal transductionGO:0007266260.013
regulation of kinase activityGO:00435493140.013
positive regulation of immune system processGO:00026842830.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of mitotic cell cycleGO:00073461890.013
response to oxygen containing compoundGO:19017003690.013
negative regulation of phosphate metabolic processGO:00459362670.013
positive regulation of programmed cell deathGO:00430682490.013
monocarboxylic acid biosynthetic processGO:0072330670.013
endoplasmic reticulum organizationGO:0007029200.013
cellular protein complex assemblyGO:00436231880.013
negative regulation of cell cycle processGO:00109481210.013
chemical homeostasisGO:00488783060.013
multi organism cellular processGO:00447641560.013
ribonucleotide biosynthetic processGO:0009260810.013
nerve developmentGO:002167540.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
cellular response to oxidative stressGO:0034599850.013
regulation of ion transportGO:00432691890.013
dephosphorylationGO:00163112090.012
positive regulation of cell deathGO:00109422630.012
immune responseGO:00069553070.012
actin filament based movementGO:0030048170.012
regulation of cell differentiationGO:00455953930.012
one carbon metabolic processGO:000673010.012
regulation of innate immune responseGO:0045088970.012
regulation of chromosome organizationGO:00330441030.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
motor neuron axon guidanceGO:000804520.012
regulation of oxidoreductase activityGO:0051341430.012
negative regulation of phosphorylationGO:00423261740.012
secretion by cellGO:00329402260.012
negative regulation of proteasomal protein catabolic processGO:1901799320.012
negative regulation of protein phosphorylationGO:00019331400.012
apoptotic signaling pathwayGO:00971902680.012
regulation of intracellular protein transportGO:00331571230.012
protein tetramerizationGO:0051262470.012
blastoderm segmentationGO:000735020.012
system processGO:00030083490.012
divalent metal ion transportGO:00708381520.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
peripheral nervous system developmentGO:000742220.012
negative regulation of transferase activityGO:00513481240.012
negative regulation of cellular amine metabolic processGO:003323930.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
negative regulation of kinase activityGO:00336731060.012
energy derivation by oxidation of organic compoundsGO:0015980430.012
alcohol metabolic processGO:00060661140.012
neurotransmitter secretionGO:000726940.012
secretionGO:00469032540.012
negative regulation of protein transportGO:0051224750.011
regulation of cell divisionGO:00513021160.011
calcium ion transmembrane transportGO:0070588760.011
cellular component morphogenesisGO:00329893140.011
positive regulation of cell differentiationGO:00455972110.011
maintenance of locationGO:00512351120.011
regulation of anatomical structure morphogenesisGO:00226032860.011
response to external biotic stimulusGO:00432072610.011
organophosphate biosynthetic processGO:00904071630.011
glycosylationGO:0070085710.011
regulation of cellular protein catabolic processGO:1903362960.011
regulation of cytokine productionGO:00018172320.011
negative regulation of intracellular transportGO:0032387600.011
regulation of atp metabolic processGO:1903578290.011
regulation of ras gtpase activityGO:00323181280.011
negative regulation of transcription from rna polymerase iii promoterGO:001648030.011
negative regulation of protein maturationGO:19033181420.011
mitotic cell cycleGO:00002783260.011
response to lipidGO:00339932060.011
sulfur compound metabolic processGO:00067901010.011
regulation of transferase activityGO:00513383550.011
protein ubiquitinationGO:00165673140.011
cofactor biosynthetic processGO:0051188310.011
autophagyGO:0006914880.011
nucleotide biosynthetic processGO:00091651090.011
compound eye developmentGO:004874910.011
rhythmic behaviorGO:000762220.011
positive regulation of transferase activityGO:00513472270.011
regulation of transporter activityGO:0032409820.011
ribose phosphate biosynthetic processGO:0046390820.011
photoreceptor cell differentiationGO:004653020.011
negative regulation of cysteine type endopeptidase activityGO:2000117480.010
inorganic ion transmembrane transportGO:00986602310.010
actin cytoskeleton organizationGO:00300362070.010
mitotic cell cycle phase transitionGO:00447721620.010
membrane hyperpolarizationGO:006008110.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
positive regulation of synaptic transmissionGO:005080640.010
myeloid cell differentiationGO:00300991170.010
metencephalon developmentGO:002203720.010
regulation of growthGO:00400081650.010
peptidyl threonine modificationGO:0018210450.010
dna dealkylationGO:0035510130.010
synaptic vesicle recyclingGO:003646530.010
sensory perception of painGO:001923340.010
monocarboxylic acid metabolic processGO:00327871850.010
regulation of cell migrationGO:00303342890.010
ubiquitin dependent protein catabolic processGO:00065112060.010
single organism cell adhesionGO:00986021790.010
response to other organismGO:00517072610.010
negative regulation of protein kinase activityGO:0006469980.010
ribonucleoprotein complex assemblyGO:0022618780.010
cellular macromolecular complex assemblyGO:00346223240.010
cellular divalent inorganic cation homeostasisGO:00725031280.010
nuclear exportGO:0051168690.010
hindbrain developmentGO:003090230.010

BRE disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.141
disease of metabolismDOID:00146672950.141
central nervous system diseaseDOID:3311860.043
nervous system diseaseDOID:8634310.043
immune system diseaseDOID:29141550.030
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.024
eye diseaseDOID:56141490.023
retinal diseaseDOID:56791180.023
sensory system diseaseDOID:00501552030.023
eye and adnexa diseaseDOID:14921500.023
neurodegenerative diseaseDOID:12891020.022
amino acid metabolic disorderDOID:9252500.018
retinal degenerationDOID:8466890.017
organ system cancerDOID:00506861640.016
musculoskeletal system diseaseDOID:172230.013
carbohydrate metabolic disorderDOID:2978550.012
muscular diseaseDOID:00800001140.010
muscle tissue diseaseDOID:661130.010