Homo sapiens

34 known processes

TOLLIP

toll interacting protein

(Aliases: IL-1RAcPIP,FLJ33531)

TOLLIP biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of protein autophosphorylationGO:0031952150.956
positive regulation of transferase activityGO:00513472270.951
activation of protein kinase activityGO:0032147900.949
positive regulation of protein kinase activityGO:00458601900.946
positive regulation of phosphorylationGO:00423273940.928
positive regulation of protein phosphorylationGO:00019343130.925
protein autophosphorylationGO:00467771230.912
regulation of protein kinase activityGO:00458592890.900
positive regulation of kinase activityGO:00336742040.883
regulation of transferase activityGO:00513383550.877
regulation of kinase activityGO:00435493140.863
regulation of mitotic cell cycleGO:00073461890.783
regulation of mitosisGO:0007088630.765
negative regulation of cellular component organizationGO:00511292350.754
positive regulation of protein autophosphorylationGO:003195490.737
regulation of nuclear divisionGO:0051783650.688
negative regulation of mitosisGO:0045839240.632
negative regulation of mitotic cell cycleGO:00459301020.585
mitotic cell cycle processGO:19030472860.583
regulation of cell cycleGO:00517263930.553
mitotic cell cycleGO:00002783260.553
mitotic nuclear divisionGO:00070671190.486
organelle fissionGO:00482851490.485
negative regulation of cell divisionGO:0051782310.467
negative regulation of cell cycle processGO:00109481210.446
negative regulation of cell cycleGO:00457861930.440
negative regulation of organelle organizationGO:00106391260.407
regulation of cell cycle processGO:00105642660.308
autophagyGO:0006914880.249
nuclear divisionGO:00002801280.240
cellular lipid metabolic processGO:00442553030.239
response to other organismGO:00517072610.228
regulation of cell divisionGO:00513021160.182
organelle assemblyGO:00709251760.122
response to biotic stimulusGO:00096072760.120
multicellular organismal agingGO:001025930.108
reactive nitrogen species metabolic processGO:200105730.101
determination of adult lifespanGO:000834020.096
protein catabolic processGO:00301633250.093
vacuole organizationGO:0007033440.091
oxidation reduction processGO:00551143960.089
regulation of sequence specific dna binding transcription factor activityGO:00510902110.085
cellular response to oxygen containing compoundGO:19017012760.083
cellular organohalogen metabolic processGO:009034520.081
reactive oxygen species metabolic processGO:0072593750.079
negative regulation of protein serine threonine kinase activityGO:0071901570.078
cellular amino acid metabolic processGO:00065201160.078
regulation of cellular amino acid metabolic processGO:000652160.077
amine metabolic processGO:0009308440.072
regulation of mapk cascadeGO:00434082620.067
mapk cascadeGO:00001652880.067
negative regulation of intracellular signal transductionGO:19025321830.066
cofactor metabolic processGO:0051186870.065
secretionGO:00469032540.061
toll like receptor 2 signaling pathwayGO:003413440.060
interleukin 6 productionGO:0032635370.058
cellular response to hypoxiaGO:0071456510.058
regulation of cellular response to stressGO:00801352440.058
regulation of secretionGO:00510461940.056
response to bacteriumGO:00096171440.055
cell divisionGO:00513011680.055
defense responseGO:00069523150.054
regulation of map kinase activityGO:00434051080.052
negative regulation of protein metabolic processGO:00512483910.051
female gamete generationGO:000729220.050
response to external biotic stimulusGO:00432072610.050
response to inorganic substanceGO:00100351270.050
nitrogen compound transportGO:00717051910.050
inorganic ion transmembrane transportGO:00986602310.049
response to oxygen containing compoundGO:19017003690.049
regulation of cellular component biogenesisGO:00440872810.049
cellular amine metabolic processGO:0044106410.048
response to oxidative stressGO:00069791210.048
regulation of synaptic plasticityGO:004816730.047
positive regulation of apoptotic processGO:00430652460.046
single organism cellular localizationGO:19025803320.046
post embryonic developmentGO:000979120.045
cellular ketone metabolic processGO:0042180800.045
regulation of cellular ketone metabolic processGO:0010565500.045
negative regulation of reactive oxygen species metabolic processGO:2000378110.045
protein localization to organelleGO:00333652800.044
purine nucleoside triphosphate metabolic processGO:00091444120.044
nucleoside triphosphate metabolic processGO:00091414220.042
regulation of protein catabolic processGO:00421761550.041
positive regulation of developmental processGO:00510943140.041
negative regulation of apoptotic processGO:00430663160.040
small molecule biosynthetic processGO:00442831570.040
cytoplasmic transportGO:00164823790.040
head developmentGO:00603221080.040
negative regulation of cellular protein metabolic processGO:00322693530.040
response to fungusGO:000962040.040
negative regulation of phosphorus metabolic processGO:00105632670.039
regulation of lipid metabolic processGO:0019216960.038
generation of neuronsGO:00486991520.037
cytokine productionGO:00018162470.036
maintenance of locationGO:00512351120.036
single organism membrane organizationGO:00448022680.035
regulation of autophagyGO:0010506520.035
regulation of cellular amine metabolic processGO:0033238110.035
lipid oxidationGO:0034440330.035
purine ribonucleotide catabolic processGO:00091544040.034
signal transduction by phosphorylationGO:00230142970.033
regulation of protein maturationGO:19033171500.033
negative regulation of protein maturationGO:19033181420.032
cell morphogenesisGO:00009022960.032
cellular macromolecular complex assemblyGO:00346223240.032
monovalent inorganic cation transportGO:00156721280.032
ion transmembrane transportGO:00342203380.032
negative regulation of protein catabolic processGO:0042177590.032
nervous system developmentGO:00073992930.031
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.031
response to abiotic stimulusGO:00096283360.031
dephosphorylationGO:00163112090.031
protein maturationGO:00516042330.031
peptidyl serine modificationGO:00182091060.030
negative regulation of tumor necrosis factor productionGO:0032720200.030
cell growthGO:00160491600.030
positive regulation of lipid storageGO:0010884100.030
protein oligomerizationGO:00512591730.030
positive regulation of cellular amine metabolic processGO:003324070.030
negative regulation of catalytic activityGO:00430863350.030
negative regulation of map kinase activityGO:0043407270.030
regulation of interleukin 6 productionGO:0032675370.030
cellular protein catabolic processGO:00442572610.029
protein processingGO:00164852260.029
cellular response to endogenous stimulusGO:00714953360.029
protein ubiquitinationGO:00165673140.029
negative regulation of immune system processGO:00026831360.029
oogenesisGO:004847720.028
wnt signaling pathwayGO:00160551560.028
regulation of secretion by cellGO:19035301770.028
cation transportGO:00068123310.028
response to metal ionGO:0010038840.028
regulation of protein serine threonine kinase activityGO:00719001790.027
endomembrane system organizationGO:00102561960.027
reactive oxygen species biosynthetic processGO:190340940.027
response to uvGO:0009411730.027
negative regulation of transferase activityGO:00513481240.026
negative regulation of protein phosphorylationGO:00019331400.026
lipid biosynthetic processGO:00086101770.026
negative regulation of phosphate metabolic processGO:00459362670.026
growthGO:00400072020.025
central nervous system developmentGO:00074171230.025
anterior posterior axis specificationGO:000994820.025
positive regulation of cell differentiationGO:00455972110.025
ribonucleoside monophosphate catabolic processGO:00091581580.024
lipid metabolic processGO:00066293810.024
apoptotic signaling pathwayGO:00971902680.024
transmembrane transportGO:00550853990.024
regulation of reactive oxygen species metabolic processGO:2000377410.024
hindbrain developmentGO:003090230.024
negative regulation of phosphorylationGO:00423261740.024
regulation of dephosphorylationGO:0035303960.024
hematopoietic or lymphoid organ developmentGO:00485341860.023
intracellular protein transportGO:00068862700.023
purine ribonucleoside metabolic processGO:00461284370.023
cellular response to extracellular stimulusGO:0031668720.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
positive regulation of transportGO:00510503360.023
regulation of reactive oxygen species biosynthetic processGO:190342630.023
establishment of protein localization to organelleGO:00725941720.023
atp catabolic processGO:00062001570.023
jnk cascadeGO:0007254800.023
ubiquitin dependent protein catabolic processGO:00065112060.022
negative regulation of protein processingGO:00109551420.022
positive regulation of organelle organizationGO:00106381950.022
negative regulation of tumor necrosis factor superfamily cytokine productionGO:1903556200.022
regulation of growthGO:00400081650.022
regulation of peptidase activityGO:00525471800.022
sensory organ developmentGO:0007423520.022
endosomal transportGO:00161971290.021
negative regulation of kinase activityGO:00336731060.021
peptidyl lysine acetylationGO:00183941010.021
cell projection organizationGO:00300302520.021
regulation of jnk cascadeGO:0046328730.021
monocarboxylic acid metabolic processGO:00327871850.021
rna processingGO:00063962550.021
positive regulation of cellular catabolic processGO:00313312840.021
positive regulation of cell deathGO:00109422630.021
negative regulation of cell deathGO:00605483450.021
negative regulation of nf kappab transcription factor activityGO:0032088510.021
purine nucleoside monophosphate metabolic processGO:00091261860.021
protein dephosphorylationGO:0006470810.021
nucleotide catabolic processGO:00091664080.020
regulation of stress activated protein kinase signaling cascadeGO:0070302850.020
erythrocyte developmentGO:004882130.020
cellular response to nutrient levelsGO:0031669690.020
negative regulation of proteolysisGO:00458611320.020
regulation of protein ubiquitinationGO:0031396950.020
purine containing compound catabolic processGO:00725234110.020
response to oxygen levelsGO:00704821000.020
response to peptidoglycanGO:003249430.020
positive regulation of immune responseGO:00507781590.020
cell cycle phase transitionGO:00447701730.019
vesicle organizationGO:0016050620.019
receptor metabolic processGO:0043112810.019
cation transmembrane transportGO:00986552380.019
dna repairGO:00062811980.019
negative regulation of multicellular organismal processGO:00512413170.019
negative regulation of protein kinase activityGO:0006469980.019
protein modification by small protein conjugationGO:00324463420.019
regulation of i kappab kinase nf kappab signalingGO:00431221620.019
nucleoside catabolic processGO:00091644080.019
regulation of protein modification by small protein conjugation or removalGO:19033201070.019
cellular response to decreased oxygen levelsGO:0036294510.019
secretion by cellGO:00329402260.019
syncytium formation by plasma membrane fusionGO:000076820.019
regulation of wnt signaling pathwayGO:00301111230.018
inner ear morphogenesisGO:004247240.018
carbohydrate metabolic processGO:00059752070.018
cellular response to oxidative stressGO:0034599850.018
cellular response to lipidGO:00713961270.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
eye developmentGO:0001654420.018
positive regulation of protein serine threonine kinase activityGO:00719021190.018
purine ribonucleoside monophosphate catabolic processGO:00091691580.018
peptidyl serine phosphorylationGO:00181051010.018
organonitrogen compound biosynthetic processGO:19015662000.018
regulation of proteolysisGO:00301622930.018
cofactor biosynthetic processGO:0051188310.018
organ morphogenesisGO:00098871470.017
organophosphate catabolic processGO:00464344300.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
negative regulation of catabolic processGO:00098951040.017
organic acid biosynthetic processGO:0016053970.017
negative regulation of mapk cascadeGO:0043409560.017
developmental programmed cell deathGO:001062330.017
defense response to bacteriumGO:0042742630.017
embryo developmentGO:00097901230.017
hair cell differentiationGO:003531520.017
divalent inorganic cation transportGO:00725111580.017
regulation of stress activated mapk cascadeGO:0032872840.017
regulation of protein processingGO:00706131500.017
regulation of innate immune responseGO:0045088970.017
lipid catabolic processGO:0016042840.017
negative regulation of protein modification processGO:00314002000.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.016
endocytosisGO:00068971590.016
response to hypoxiaGO:0001666960.016
alcohol metabolic processGO:00060661140.016
immune responseGO:00069553070.016
neuron differentiationGO:00301821380.016
tissue homeostasisGO:0001894630.016
positive regulation of apoptotic signaling pathwayGO:2001235700.016
fatty acid metabolic processGO:00066311150.016
sequestering of metal ionGO:0051238240.016
regulation of protein transportGO:00512232130.016
positive regulation of lipid metabolic processGO:0045834500.016
cell part morphogenesisGO:00329901370.016
regulation of cytokine productionGO:00018172320.016
negative regulation of hydrolase activityGO:00513461820.016
segmentationGO:003528240.016
stress activated mapk cascadeGO:0051403930.016
cellular macromolecule catabolic processGO:00442653800.016
positive regulation of secretion by cellGO:19035321080.016
positive regulation of innate immune responseGO:0045089790.015
negative regulation of cytokine productionGO:0001818820.015
metencephalon developmentGO:002203720.015
endochondral bone morphogenesisGO:006035030.015
i kappab kinase nf kappab signalingGO:00072491660.015
cell projection morphogenesisGO:00488581290.015
negative regulation of interleukin 6 productionGO:0032715130.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
myeloid cell homeostasisGO:0002262340.015
positive regulation of ion transportGO:0043270870.015
nuclear transportGO:00511691790.015
neurological system processGO:00508771630.015
organic hydroxy compound metabolic processGO:19016151470.015
atp metabolic processGO:00460341760.015
cell morphogenesis involved in differentiationGO:00009041440.015
regulation of protein complex assemblyGO:00432541470.015
response to radiationGO:00093141510.015
response to organonitrogen compoundGO:00102431560.015
neuron developmentGO:00486661130.015
cellular response to growth factor stimulusGO:00713631970.015
nucleoside monophosphate metabolic processGO:00091231910.015
modification dependent macromolecule catabolic processGO:00436322120.015
reproductive processGO:00224141060.015
g1 s transition of mitotic cell cycleGO:0000082780.015
compound eye developmentGO:004874910.014
regulation of apoptotic signaling pathwayGO:20012331750.014
spermatid developmentGO:000728640.014
regulation of protein dephosphorylationGO:0035304180.014
cell developmentGO:00484683280.014
exocytosisGO:0006887710.014
protein targetingGO:00066051870.014
cell cell signalingGO:00072671550.014
response to nutrient levelsGO:0031667810.014
positive regulation of lipid biosynthetic processGO:0046889220.014
peptidyl lysine modificationGO:00182051440.014
regulation of hormone levelsGO:00108171250.014
positive regulation of programmed cell deathGO:00430682490.014
tumor necrosis factor superfamily cytokine productionGO:0071706450.014
regulation of peptidyl serine phosphorylationGO:0033135500.014
purine nucleotide catabolic processGO:00061954050.014
pattern recognition receptor signaling pathwayGO:0002221480.014
small molecule catabolic processGO:0044282920.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
response to extracellular stimulusGO:0009991850.014
agingGO:0007568660.014
endosome transport via multivesicular body sorting pathwayGO:003250930.014
modification dependent protein catabolic processGO:00199412090.014
hemopoiesisGO:00300971800.014
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.014
cellular response to biotic stimulusGO:0071216710.014
positive regulation of secretionGO:00510471160.014
response to decreased oxygen levelsGO:0036293960.014
regulation of cellular response to growth factor stimulusGO:0090287760.013
negative regulation of growthGO:0045926970.013
blastoderm segmentationGO:000735020.013
cellular lipid catabolic processGO:0044242650.013
purine ribonucleoside triphosphate catabolic processGO:00092073910.013
cellular chemical homeostasisGO:00550821800.013
cilium organizationGO:0044782680.013
regulation of catecholamine secretionGO:005043310.013
positive regulation of mapk cascadeGO:00434101900.013
single organism carbohydrate metabolic processGO:00447231930.013
immune response regulating signaling pathwayGO:0002764970.013
regulation of cholesterol metabolic processGO:009018140.013
cellular response to cytokine stimulusGO:00713451810.013
positive regulation of immune system processGO:00026842830.013
proteasomal protein catabolic processGO:00104981760.013
regulation of ion transmembrane transportGO:00347651320.013
macroautophagyGO:0016236390.013
cellular response to molecule of bacterial originGO:0071219620.013
mitotic cell cycle phase transitionGO:00447721620.013
glycosyl compound catabolic processGO:19016584130.013
neuromuscular junction developmentGO:000752830.013
myeloid cell differentiationGO:00300991170.013
cell cycle g1 s phase transitionGO:0044843800.013
regulation of tumor necrosis factor productionGO:0032680430.013
gastrulation with mouth forming secondGO:000170210.013
carboxylic acid biosynthetic processGO:0046394970.013
skin developmentGO:0043588760.013
regulation of ion transportGO:00432691890.012
negative regulation of peptidase activityGO:0010466910.012
chemical homeostasisGO:00488783060.012
regulation of cell growthGO:00015581350.012
purine nucleoside catabolic processGO:00061523980.012
circadian behaviorGO:004851220.012
activation of innate immune responseGO:0002218550.012
cellular response to toxic substanceGO:009723740.012
spermatid differentiationGO:004851540.012
positive regulation of hormone biosynthetic processGO:004688640.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
apoptotic mitochondrial changesGO:0008637570.012
cellular response to oxygen levelsGO:0071453550.012
dopaminergic neuron differentiationGO:007154210.012
innate immune responseGO:00450871780.012
immune response activating signal transductionGO:0002757900.012
nucleoside triphosphate catabolic processGO:00091433940.012
regulation of homeostatic processGO:00328441210.012
defense response to fungusGO:005083240.012
meiotic chromosome segregationGO:004513240.012
protein complex disassemblyGO:0043241520.012
protein localization to membraneGO:00726571600.012
locomotory behaviorGO:000762610.012
positive regulation of steroid hormone biosynthetic processGO:009003120.012
regulation of hydrogen peroxide mediated programmed cell deathGO:190129840.012
calcium ion transmembrane transportGO:0070588760.012
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.012
ribonucleotide catabolic processGO:00092614050.011
response to endoplasmic reticulum stressGO:0034976490.011
system processGO:00030083490.011
negative regulation of cellular amine metabolic processGO:003323930.011
cerebellum developmentGO:002154920.011
protein acetylationGO:00064731160.011
cellular response to uvGO:0034644320.011
peripheral nervous system developmentGO:000742220.011
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.011
single organism membrane fusionGO:0044801370.011
somatic stem cell maintenanceGO:003501940.011
positive regulation of catabolic processGO:00098963100.011
ion homeostasisGO:00508012300.011
brain developmentGO:0007420970.011
cation homeostasisGO:00550801890.011
catecholamine secretionGO:005043210.011
regulation of transmembrane transportGO:00347621390.011
kidney developmentGO:0001822530.011
embryonic morphogenesisGO:0048598850.011
cellular component morphogenesisGO:00329893140.011
embryo development ending in birth or egg hatchingGO:0009792340.011
actin filament based processGO:00300292240.011
negative regulation of transportGO:00510511760.011
epithelial cell differentiationGO:00308551410.011
neuron projection developmentGO:00311751060.011
positive regulation of nf kappab transcription factor activityGO:0051092810.011
protein acylationGO:00435431380.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
porphyrin containing compound metabolic processGO:0006778100.010
behavioral response to ethanolGO:004814920.010
regulation of steroid metabolic processGO:0019218320.010
cell projection assemblyGO:00300311260.010
ossificationGO:00015031210.010
posttranscriptional regulation of gene expressionGO:00106082130.010
negative regulation of cell cycle phase transitionGO:1901988890.010
nephric duct developmentGO:007217640.010
macromolecular complex disassemblyGO:0032984600.010
tube closureGO:006060630.010
defense response to other organismGO:00985421290.010
homeostasis of number of cellsGO:0048872400.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
negative regulation of hydrogen peroxide mediated programmed cell deathGO:190129930.010
cellular component disassemblyGO:0022411920.010
positive regulation of amine transportGO:005195420.010
regulation of anatomical structure sizeGO:00900661010.010

TOLLIP disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.034
inherited metabolic disorderDOID:6552420.034
central nervous system diseaseDOID:3311860.017
nervous system diseaseDOID:8634310.017
neurodegenerative diseaseDOID:12891020.016
disease of cellular proliferationDOID:145661740.013
organ system cancerDOID:00506861640.012
cancerDOID:1621670.012