Homo sapiens

60 known processes

APTX

aprataxin

(Aliases: FHA-HIT,EAOH,AXA1,AOA,MGC1072,AOA1,FLJ20157,EOAHA)

APTX biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811980.911
dna damage response detection of dna damageGO:004276930.808
cellular macromolecule catabolic processGO:00442653800.791
cellular response to dna damage stimulusGO:00069743790.707
dna ligation involved in dna repairGO:005110340.690
double strand break repairGO:00063021010.689
base excision repairGO:0006284210.516
pro b cell differentiationGO:000232810.458
protein ubiquitinationGO:00165673140.339
nucleic acid phosphodiester bond hydrolysisGO:00903051020.298
vesicle mediated transportGO:00161923710.274
immunoglobulin v d j recombinationGO:003315210.269
response to abiotic stimulusGO:00096283360.229
protein modification by small protein conjugationGO:00324463420.221
response to oxidative stressGO:00069791210.176
protein autoubiquitinationGO:0051865370.154
meiotic chromosome segregationGO:004513240.153
response to radiationGO:00093141510.153
limbic system developmentGO:002176130.150
dna ligationGO:0006266100.130
Mouse
response to ionizing radiationGO:0010212650.121
cytoplasmic transportGO:00164823790.111
cellular response to ionizing radiationGO:0071479320.097
hippocampus developmentGO:002176610.087
cell type specific apoptotic processGO:00972851250.083
viral life cycleGO:00190581320.074
establishment of protein localization to organelleGO:00725941720.073
non recombinational repairGO:0000726140.072
negative regulation of apoptotic processGO:00430663160.071
regulation of growthGO:00400081650.071
response to gamma radiationGO:0010332140.070
cytokinesisGO:0000910960.070
t cell activationGO:0042110990.064
positive regulation of developmental processGO:00510943140.062
macromolecule glycosylationGO:0043413630.060
cellular response to abiotic stimulusGO:00712141170.060
regulation of cellular response to stressGO:00801352440.059
glycoprotein biosynthetic processGO:0009101910.058
post embryonic developmentGO:000979120.058
negative regulation of dna metabolic processGO:0051053570.057
response to drugGO:0042493810.056
apoptotic signaling pathwayGO:00971902680.054
microtubule cytoskeleton organizationGO:00002261760.053
regulation of protein kinase activityGO:00458592890.053
positive regulation of dna metabolic processGO:0051054730.053
negative regulation of organelle assemblyGO:190211670.052
regulation of protein ubiquitinationGO:0031396950.051
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.048
protein targetingGO:00066051870.047
regulation of viral processGO:00507921030.046
signal transduction involved in regulation of gene expressionGO:002301910.046
somatic diversification of immunoglobulins involved in immune responseGO:000220830.046
lymphocyte activationGO:00466491330.046
negative regulation of protein modification processGO:00314002000.044
negative regulation of organelle organizationGO:00106391260.044
membrane organizationGO:00610242920.043
cell agingGO:0007569520.043
regulation of kinase activityGO:00435493140.042
cellular protein catabolic processGO:00442572610.042
dna recombinationGO:0006310770.042
centrosome cycleGO:0007098320.042
single strand break repairGO:000001260.041
regulation of cell cycle processGO:00105642660.041
negative regulation of protein metabolic processGO:00512483910.041
protein autoprocessingGO:001654040.041
protein localization to organelleGO:00333652800.040
nucleoside triphosphate metabolic processGO:00091414220.040
chromosome segregationGO:00070591140.040
mitochondrion organizationGO:00070051560.040
organelle assemblyGO:00709251760.039
multi organism cellular processGO:00447641560.039
central nervous system developmentGO:00074171230.039
negative regulation of catalytic activityGO:00430863350.038
viral processGO:00160321460.038
response to decreased oxygen levelsGO:0036293960.038
hemopoiesisGO:00300971800.038
double strand break repair via nonhomologous end joiningGO:0006303100.038
negative regulation of cell cycleGO:00457861930.035
negative regulation of cellular component organizationGO:00511292350.035
protein maturationGO:00516042330.035
positive regulation of transportGO:00510503360.035
replicative cell agingGO:000130230.035
system processGO:00030083490.035
lipid biosynthetic processGO:00086101770.034
nucleoside monophosphate metabolic processGO:00091231910.033
v d j recombinationGO:003315130.033
immune system developmentGO:00025201950.032
nucleoside catabolic processGO:00091644080.032
b cell activationGO:0042113330.032
intracellular protein transportGO:00068862700.032
lymphoid progenitor cell differentiationGO:000232030.031
regulation of transferase activityGO:00513383550.031
positive regulation of cellular catabolic processGO:00313312840.031
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.031
leukocyte activationGO:00453211640.031
negative regulation of protein phosphorylationGO:00019331400.030
cytoskeleton dependent cytokinesisGO:0061640220.030
centriole replicationGO:0007099130.029
single organism membrane organizationGO:00448022680.029
receptor mediated endocytosisGO:0006898840.029
interspecies interaction between organismsGO:00444191560.029
regulation of cell growthGO:00015581350.028
cellular response to radiationGO:0071478650.028
purine ribonucleoside metabolic processGO:00461284370.028
microtubule organizing center organizationGO:0031023620.028
glycosyl compound catabolic processGO:19016584130.028
glycosylationGO:0070085710.028
regulation of protein transportGO:00512232130.027
cellular amino acid metabolic processGO:00065201160.027
positive regulation of cell developmentGO:0010720920.027
ribonucleotide catabolic processGO:00092614050.027
regulation of cell cycleGO:00517263930.026
negative regulation of cell deathGO:00605483450.026
amine metabolic processGO:0009308440.026
regulation of ligase activityGO:0051340290.026
telencephalon developmentGO:0021537170.026
purine nucleoside catabolic processGO:00061523980.026
covalent chromatin modificationGO:00165692540.025
regulation of protein modification by small protein conjugation or removalGO:19033201070.025
cell divisionGO:00513011680.025
single organism cellular localizationGO:19025803320.025
determination of adult lifespanGO:000834020.024
negative regulation of viral processGO:0048525660.024
organophosphate catabolic processGO:00464344300.024
glycoprotein metabolic processGO:00091001100.023
guanosine containing compound catabolic processGO:19010692390.023
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.023
negative regulation of cell proliferationGO:00082852280.023
single organism carbohydrate metabolic processGO:00447231930.023
negative regulation of cellular protein metabolic processGO:00322693530.022
nucleotide excision repairGO:0006289310.022
negative regulation of cell cycle processGO:00109481210.022
ubiquitin dependent protein catabolic processGO:00065112060.021
symbiosis encompassing mutualism through parasitismGO:00444031560.021
endocytosisGO:00068971590.021
modification dependent protein catabolic processGO:00199412090.021
positive regulation of cell growthGO:0030307480.020
centrosome organizationGO:0051297580.020
purine ribonucleotide catabolic processGO:00091544040.020
macromolecule methylationGO:0043414970.020
brain developmentGO:0007420970.020
nuclear transportGO:00511691790.020
regulation of multi organism processGO:00439001570.020
t cell differentiation in thymusGO:003307740.020
protein glycosylationGO:0006486620.019
regulation of anatomical structure morphogenesisGO:00226032860.019
regulation of dna metabolic processGO:00510521530.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
cell growthGO:00160491600.019
nucleoside triphosphate catabolic processGO:00091433940.019
response to hypoxiaGO:0001666960.019
gtp metabolic processGO:00460392390.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
protein localization to nucleusGO:00345041360.018
regulation of response to dna damage stimulusGO:2001020940.018
interaction with hostGO:0051701420.018
regulation of protein import into nucleusGO:0042306780.018
anatomical structure homeostasisGO:00602491000.018
carbohydrate derivative biosynthetic processGO:19011372070.018
negative regulation of protein ubiquitinationGO:0031397350.018
regulation of cell differentiationGO:00455953930.018
immune responseGO:00069553070.018
protein adp ribosylationGO:000647190.018
hematopoietic or lymphoid organ developmentGO:00485341860.017
nervous system developmentGO:00073992930.017
cell projection morphogenesisGO:00488581290.017
negative regulation of nf kappab transcription factor activityGO:0032088510.017
mitotic cell cycleGO:00002783260.017
cellular response to uvGO:0034644320.017
generation of neuronsGO:00486991520.017
negative regulation of phosphorylationGO:00423261740.016
cell activationGO:00017752130.016
neuromuscular junction developmentGO:000752830.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of cellular amine metabolic processGO:0033238110.016
nucleotide catabolic processGO:00091664080.016
protein catabolic processGO:00301633250.016
purine nucleotide catabolic processGO:00061954050.016
negative regulation of transferase activityGO:00513481240.016
positive regulation of catabolic processGO:00098963100.016
proteasomal protein catabolic processGO:00104981760.016
positive regulation of cell proliferationGO:00082843010.015
protein importGO:00170381300.015
cellular component disassemblyGO:0022411920.015
secretion by cellGO:00329402260.015
leukocyte differentiationGO:0002521980.015
meiosis iGO:000712740.014
regulation of protein catabolic processGO:00421761550.014
modification by host of symbiont morphology or physiologyGO:0051851260.014
regulation of protein targetingGO:1903533910.014
histone modificationGO:00165702510.014
lymphocyte differentiationGO:0030098350.014
neurological system processGO:00508771630.014
regulation of growth rateGO:004000910.014
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
regulation of establishment of protein localizationGO:00702012420.013
microtubule based processGO:00070172100.013
negative regulation of phosphorus metabolic processGO:00105632670.013
nucleoside monophosphate catabolic processGO:00091251590.013
dna modificationGO:0006304270.013
regulation of intracellular transportGO:00323861950.013
transmembrane transportGO:00550853990.013
mitochondrial transportGO:0006839600.013
regulation of ion transportGO:00432691890.012
dna catabolic processGO:0006308490.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
positive regulation of immune responseGO:00507781590.012
centrosome separationGO:005129930.012
negative regulation of growthGO:0045926970.012
positive regulation of nf kappab transcription factor activityGO:0051092810.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
negative regulation of protein kinase activityGO:0006469980.012
forebrain developmentGO:0030900260.012
divalent metal ion transportGO:00708381520.012
carbohydrate metabolic processGO:00059752070.012
rna interferenceGO:001624640.012
negative regulation of phosphate metabolic processGO:00459362670.012
detection of stimulusGO:0051606850.012
protein processingGO:00164852260.012
positive regulation by host of viral transcriptionGO:0043923110.012
response to light stimulusGO:0009416870.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
embryonic eye morphogenesisGO:004804820.011
cell part morphogenesisGO:00329901370.011
response to reactive oxygen speciesGO:0000302610.011
cellular response to oxidative stressGO:0034599850.011
negative regulation of centrosome cycleGO:004660640.011
growthGO:00400072020.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
multicellular organismal agingGO:001025930.011
positive regulation of t cell apoptotic processGO:007023440.011
regulation of microtubule based processGO:0032886740.011
regulation of cytoskeleton organizationGO:00514931770.011
response to toxic substanceGO:0009636370.011
positive regulation of hydrolase activityGO:00513453310.011
nitrogen compound transportGO:00717051910.011
negative regulation of protein processingGO:00109551420.011
defense responseGO:00069523150.011
modulation by host of symbiont transcriptionGO:0052472200.011
regulation of cellular component movementGO:00512703340.011
hindbrain developmentGO:003090230.011
cell projection assemblyGO:00300311260.011
telomere maintenanceGO:0000723320.011
response to caffeineGO:003100030.011
secretionGO:00469032540.011
cell projection organizationGO:00300302520.011
multicellular organismal signalingGO:0035637340.010
regulation of immune responseGO:00507762010.010
regulation of nucleocytoplasmic transportGO:0046822980.010
nuclear importGO:00511701060.010
signal transduction by p53 class mediatorGO:0072331720.010
head developmentGO:00603221080.010
ribonucleoside catabolic processGO:00424544060.010
mitotic cell cycle processGO:19030472860.010
response to woundingGO:00096111680.010
negative regulation of intracellular signal transductionGO:19025321830.010
positive regulation of locomotionGO:00400171860.010
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.010
cell morphogenesisGO:00009022960.010
response to uvGO:0009411730.010

APTX disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.451
neonatal period electroclinical syndromeDOID:0050702190.451
electroclinical syndromeDOID:0050701320.451
brain diseaseDOID:936730.451
epilepsy syndromeDOID:1826410.451
nervous system diseaseDOID:8634310.451
immune system diseaseDOID:29141550.209
disease of cellular proliferationDOID:145661740.098
cancerDOID:1621670.026
organ system cancerDOID:00506861640.026
ohtahara syndromeDOID:0050709170.019
idiopathic generalized epilepsyDOID:1827210.017
hematopoietic system diseaseDOID:741000.011