Homo sapiens

0 known processes

POLE2

polymerase (DNA directed), epsilon 2 (p59 subunit)

(Aliases: DPE2)

POLE2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna dependent dna replicationGO:0006261440.981
Yeast
dna repairGO:00062811980.965
Yeast
dna replicationGO:00062601160.901
Yeast
regulation of transcription by chromatin organizationGO:003440110.872
cellular response to dna damage stimulusGO:00069743790.810
Yeast
double strand break repairGO:00063021010.756
heterochromatin organizationGO:007082860.688
dna biosynthetic processGO:0071897400.592
Yeast
dna recombinationGO:0006310770.582
dna strand elongation involved in dna replicationGO:000627130.552
nuclear divisionGO:00002801280.328
post embryonic developmentGO:000979120.324
Worm
chromosome segregationGO:00070591140.316
chromatin organizationGO:00063253510.236
double strand break repair via homologous recombinationGO:0000724500.225
regulation of cell cycleGO:00517263930.192
mitotic cell cycleGO:00002783260.173
purine ribonucleoside monophosphate metabolic processGO:00091671860.166
purine containing compound catabolic processGO:00725234110.164
establishment of nucleus localizationGO:004002310.164
purine ribonucleoside metabolic processGO:00461284370.162
nucleoside monophosphate metabolic processGO:00091231910.155
dna strand elongationGO:002261650.140
ribonucleoside monophosphate metabolic processGO:00091611870.130
mitotic cell cycle phase transitionGO:00447721620.124
sister chromatid segregationGO:0000819540.124
leading strand elongationGO:000627210.121
histone acetylationGO:0016573930.114
protein acetylationGO:00064731160.112
recombinational repairGO:0000725500.109
cellular macromolecular complex assemblyGO:00346223240.106
translesion synthesisGO:001998580.100
Yeast
nucleoside triphosphate metabolic processGO:00091414220.098
nuclear migrationGO:000709710.091
nucleoside monophosphate catabolic processGO:00091251590.089
postreplication repairGO:0006301120.089
Yeast
dna conformation changeGO:00711031130.087
non recombinational repairGO:0000726140.086
organelle fissionGO:00482851490.086
mitotic cell cycle processGO:19030472860.083
nucleus localizationGO:005164710.082
embryo developmentGO:00097901230.082
Worm
regulation of mitotic cell cycleGO:00073461890.081
regulation of gene expression epigeneticGO:0040029730.080
sister chromatid cohesionGO:0007062240.079
nucleoside phosphate biosynthetic processGO:19012931090.078
mitotic nuclear divisionGO:00070671190.074
peptidyl lysine modificationGO:00182051440.073
cell agingGO:0007569520.070
response to abiotic stimulusGO:00096283360.069
purine nucleoside monophosphate metabolic processGO:00091261860.068
meiotic chromosome segregationGO:004513240.067
internal peptidyl lysine acetylationGO:0018393970.066
microtubule based processGO:00070172100.065
ribonucleoside triphosphate metabolic processGO:00091994120.065
chromatin assemblyGO:0031497610.063
negative regulation of mitotic cell cycle phase transitionGO:1901991850.060
carbohydrate derivative biosynthetic processGO:19011372070.057
purine nucleoside monophosphate catabolic processGO:00091281580.057
gene conversionGO:003582210.057
reproductive structure developmentGO:0048608550.053
Worm
internal protein amino acid acetylationGO:00064751010.051
negative regulation of cell cycleGO:00457861930.051
purine ribonucleoside monophosphate catabolic processGO:00091691580.049
vesicle mediated transportGO:00161923710.049
microtubule cytoskeleton organizationGO:00002261760.047
negative regulation of mitotic cell cycleGO:00459301020.047
nucleoside triphosphate catabolic processGO:00091433940.046
regulation of dna metabolic processGO:00510521530.045
gene silencingGO:0016458490.045
reproductionGO:0000003630.045
Worm
organophosphate catabolic processGO:00464344300.044
negative regulation of gene expression epigeneticGO:0045814190.044
ribonucleotide catabolic processGO:00092614050.042
base excision repairGO:0006284210.041
mitotic cell cycle checkpointGO:0007093680.041
dna damage checkpointGO:0000077680.041
g2 m transition of mitotic cell cycleGO:0000086410.041
response to ionizing radiationGO:0010212650.039
nucleotide biosynthetic processGO:00091651090.039
regulation of cellular amine metabolic processGO:0033238110.039
ribonucleoside triphosphate catabolic processGO:00092033910.038
protein acylationGO:00435431380.036
ribonucleoside monophosphate catabolic processGO:00091581580.036
cell cycle phase transitionGO:00447701730.036
regulation of mitotic cell cycle phase transitionGO:19019901180.035
mitotic sister chromatid segregationGO:0000070530.034
negative regulation of cell cycle phase transitionGO:1901988890.034
chromatin assembly or disassemblyGO:0006333780.034
nucleoside phosphate catabolic processGO:19012924120.033
negative regulation of cell cycle processGO:00109481210.033
cell divisionGO:00513011680.033
cell cycle checkpointGO:00000751170.032
agingGO:0007568660.032
organophosphate biosynthetic processGO:00904071630.031
regulation of cell cycle processGO:00105642660.031
mitotic dna damage checkpointGO:0044773280.031
regulation of cell cycle phase transitionGO:19019871260.031
embryo development ending in birth or egg hatchingGO:0009792340.029
Worm
chromatin modificationGO:00165682980.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
protein dna complex subunit organizationGO:0071824800.027
dna geometric changeGO:0032392320.027
dna integrity checkpointGO:0031570710.027
nucleus organizationGO:0006997280.026
regulation of proteolysisGO:00301622930.026
response to radiationGO:00093141510.026
cellular response to ionizing radiationGO:0071479320.026
peptidyl lysine acetylationGO:00183941010.025
reproductive processGO:00224141060.025
Worm
positive regulation of immune system processGO:00026842830.025
histone h3 acetylationGO:0043966450.025
atp catabolic processGO:00062001570.025
chromatin silencingGO:0006342120.024
cell activationGO:00017752130.024
purine ribonucleoside catabolic processGO:00461303980.023
cellular response to radiationGO:0071478650.023
determination of adult lifespanGO:000834020.023
purine nucleoside catabolic processGO:00061523980.023
cellular response to abiotic stimulusGO:00712141170.022
regenerationGO:003109940.022
chromatin remodelingGO:0006338550.021
cellular macromolecule catabolic processGO:00442653800.021
organelle localizationGO:0051640840.021
proteolysis involved in cellular protein catabolic processGO:00516032440.020
cell cycle g2 m phase transitionGO:0044839430.020
dna packagingGO:0006323770.020
single organism reproductive processGO:0044702980.020
Worm
reproductive system developmentGO:0061458560.020
Worm
purine nucleotide catabolic processGO:00061954050.019
maintenance of locationGO:00512351120.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
purine ribonucleotide catabolic processGO:00091544040.019
apoptotic signaling pathwayGO:00971902680.019
cellular ketone metabolic processGO:0042180800.018
regulation of g2 m transition of mitotic cell cycleGO:0010389200.018
negative regulation of cell deathGO:00605483450.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
reciprocal meiotic recombinationGO:000713140.017
modification dependent macromolecule catabolic processGO:00436322120.017
intra s dna damage checkpointGO:003157340.017
nucleosome organizationGO:0034728660.017
cellular amino acid metabolic processGO:00065201160.017
protein localization to organelleGO:00333652800.017
nucleotide catabolic processGO:00091664080.016
covalent chromatin modificationGO:00165692540.016
dna duplex unwindingGO:0032508300.016
mitotic dna integrity checkpointGO:0044774300.015
negative regulation of cellular protein metabolic processGO:00322693530.015
protein catabolic processGO:00301633250.015
histone modificationGO:00165702510.015
meiosis iGO:000712740.015
organonitrogen compound biosynthetic processGO:19015662000.015
protein processingGO:00164852260.015
single organism cellular localizationGO:19025803320.014
blastocyst developmentGO:000182430.014
regulation of protein catabolic processGO:00421761550.014
negative regulation of catalytic activityGO:00430863350.014
positive regulation of cell proliferationGO:00082843010.014
centromere complex assemblyGO:0034508100.014
g1 s transition of mitotic cell cycleGO:0000082780.014
ubiquitin dependent protein catabolic processGO:00065112060.014
cellular amine metabolic processGO:0044106410.013
dephosphorylationGO:00163112090.013
atp metabolic processGO:00460341760.013
cardiovascular system developmentGO:00723582620.013
oxidation reduction processGO:00551143960.013
negative regulation of cellular component organizationGO:00511292350.013
nucleotide excision repairGO:0006289310.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
development of primary sexual characteristicsGO:0045137350.013
Worm
regulation of response to dna damage stimulusGO:2001020940.013
multicellular organismal agingGO:001025930.012
positive regulation of cellular catabolic processGO:00313312840.012
protein dna complex assemblyGO:0065004640.012
histone exchangeGO:004348630.012
regulation of cellular response to stressGO:00801352440.012
regulation of dna replicationGO:0006275680.012
cell cycle g1 s phase transitionGO:0044843800.012
dna catabolic processGO:0006308490.012
endomembrane system organizationGO:00102561960.011
protein maturationGO:00516042330.011
maintenance of location in cellGO:0051651620.011
regulation of cell activationGO:00508651250.011
cell cell signalingGO:00072671550.011
cell morphogenesisGO:00009022960.011
regulation of protein localizationGO:00328802960.011
glycosyl compound catabolic processGO:19016584130.011
modification dependent protein catabolic processGO:00199412090.011
regulation of cellular component biogenesisGO:00440872810.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
protein targetingGO:00066051870.011
negative regulation of proteolysisGO:00458611320.010
positive regulation of phosphorylationGO:00423273940.010
negative regulation of apoptotic processGO:00430663160.010
endocytosisGO:00068971590.010
intracellular protein transportGO:00068862700.010
negative regulation of programmed cell deathGO:00430693210.010
regulation of chromosome organizationGO:00330441030.010
positive regulation of catabolic processGO:00098963100.010

POLE2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.190
disease of cellular proliferationDOID:145661740.190
cancerDOID:1621670.190
inherited metabolic disorderDOID:6552420.052
disease of metabolismDOID:00146672950.052
immune system diseaseDOID:29141550.019
gastrointestinal system cancerDOID:3119520.013
large intestine cancerDOID:5672290.013
intestinal cancerDOID:10155290.013
colorectal cancerDOID:9256290.013