Homo sapiens

60 known processes

GOT1

glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)

(Aliases: GIG18)

GOT1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.527
cellular amino acid metabolic processGO:00065201160.471
dicarboxylic acid biosynthetic processGO:004365040.321
Yeast Mouse
dicarboxylic acid metabolic processGO:0043648290.282
glutamate metabolic processGO:0006536100.280
Mouse
tricarboxylic acid cycleGO:000609940.245
tricarboxylic acid metabolic processGO:007235040.224
citrate metabolic processGO:000610120.210
cellular amino acid biosynthetic processGO:0008652300.203
Yeast Mouse
female gamete generationGO:000729220.192
oxidation reduction processGO:00551143960.181
dicarboxylic acid catabolic processGO:004364990.176
cellular amino acid catabolic processGO:0009063310.153
oogenesisGO:004847720.123
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.107
positive regulation of hydrolase activityGO:00513453310.104
nervous system developmentGO:00073992930.104
multicellular organismal agingGO:001025930.100
positive regulation of proteolysisGO:00458621420.094
alpha amino acid metabolic processGO:1901605720.093
regulation of peptidase activityGO:00525471800.091
small molecule biosynthetic processGO:00442831570.087
Yeast Mouse
positive regulation of peptidase activityGO:0010952880.085
zymogen activationGO:0031638700.081
sulfur compound metabolic processGO:00067901010.080
vesicle mediated transportGO:00161923710.079
trna aminoacylationGO:0043039120.078
determination of adult lifespanGO:000834020.078
alpha amino acid catabolic processGO:1901606260.076
protein processingGO:00164852260.075
embryo developmentGO:00097901230.073
positive regulation of cysteine type endopeptidase activityGO:2001056790.072
regulation of cysteine type endopeptidase activityGO:20001161270.069
sulfur compound biosynthetic processGO:0044272380.068
regulation of endopeptidase activityGO:00525481700.067
organonitrogen compound biosynthetic processGO:19015662000.067
Yeast Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.064
aerobic respirationGO:000906070.059
cation transmembrane transportGO:00986552380.055
chemical homeostasisGO:00488783060.055
Mouse
nadh dehydrogenase complex assemblyGO:0010257160.054
carboxylic acid catabolic processGO:0046395710.053
protein maturationGO:00516042330.052
negative regulation of apoptotic processGO:00430663160.051
mitochondrial respiratory chain complex i biogenesisGO:0097031160.050
regulation of proteolysisGO:00301622930.048
carbohydrate metabolic processGO:00059752070.047
Mouse
cofactor biosynthetic processGO:0051188310.047
amine metabolic processGO:0009308440.047
purine nucleoside triphosphate metabolic processGO:00091444120.046
positive regulation of cell deathGO:00109422630.045
coenzyme metabolic processGO:0006732650.044
positive regulation of programmed cell deathGO:00430682490.043
neuromuscular junction developmentGO:000752830.043
thioester biosynthetic processGO:003538460.042
carboxylic acid biosynthetic processGO:0046394970.041
Yeast Mouse
positive regulation of cellular component organizationGO:00511303760.041
cation transportGO:00068123310.041
activation of cysteine type endopeptidase activityGO:0097202570.041
regulation of cellular amine metabolic processGO:0033238110.040
generation of precursor metabolites and energyGO:0006091680.040
cellular protein complex assemblyGO:00436231880.040
system processGO:00030083490.039
purine ribonucleoside metabolic processGO:00461284370.039
acyl coa biosynthetic processGO:007161660.039
single organism carbohydrate metabolic processGO:00447231930.038
Mouse
positive regulation of catabolic processGO:00098963100.038
protein oligomerizationGO:00512591730.036
cellular macromolecule catabolic processGO:00442653800.036
cellular ion homeostasisGO:00068731680.035
posttranscriptional regulation of gene expressionGO:00106082130.035
nucleoside triphosphate metabolic processGO:00091414220.034
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.033
pyridine nucleotide metabolic processGO:0019362140.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
spermatid differentiationGO:004851540.032
organic acid biosynthetic processGO:0016053970.031
Yeast Mouse
cellular response to cytokine stimulusGO:00713451810.031
isocitrate metabolic processGO:000610210.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
glutamate biosynthetic processGO:000653730.030
maintenance of locationGO:00512351120.030
positive regulation of endopeptidase activityGO:0010950840.030
ion transmembrane transportGO:00342203380.030
regulation of membrane potentialGO:0042391950.029
energy derivation by oxidation of organic compoundsGO:0015980430.029
ribonucleoside triphosphate metabolic processGO:00091994120.029
cellular amine metabolic processGO:0044106410.029
glutamine family amino acid metabolic processGO:0009064170.028
Mouse
regulation of cellular amino acid metabolic processGO:000652160.028
cellular component disassemblyGO:0022411920.027
cellular cation homeostasisGO:00300031630.027
anatomical structure formation involved in morphogenesisGO:00486462840.027
response to abiotic stimulusGO:00096283360.027
carbohydrate derivative biosynthetic processGO:19011372070.027
blood vessel morphogenesisGO:00485141620.027
negative regulation of cell deathGO:00605483450.027
glutamine family amino acid biosynthetic processGO:000908450.027
cellular macromolecular complex assemblyGO:00346223240.027
metal ion transportGO:00300012720.026
negative regulation of programmed cell deathGO:00430693210.026
pyruvate metabolic processGO:0006090260.026
actin filament based processGO:00300292240.026
positive regulation of organelle organizationGO:00106381950.026
calcium ion transportGO:00068161470.026
protein acylationGO:00435431380.025
cofactor metabolic processGO:0051186870.025
cellular respirationGO:0045333210.025
atp metabolic processGO:00460341760.025
negative regulation of intracellular signal transductionGO:19025321830.025
regulation of cellular component biogenesisGO:00440872810.024
hindbrain developmentGO:003090230.024
anion transportGO:00068201610.024
cellular ketone metabolic processGO:0042180800.023
positive regulation of immune system processGO:00026842830.023
immune responseGO:00069553070.023
positive regulation of apoptotic processGO:00430652460.023
purine ribonucleoside catabolic processGO:00461303980.023
ribonucleotide catabolic processGO:00092614050.022
cellular chemical homeostasisGO:00550821800.022
mitochondrial respiratory chain complex assemblyGO:0033108230.022
response to oxygen containing compoundGO:19017003690.022
oxidoreduction coenzyme metabolic processGO:0006733190.022
inorganic cation transmembrane transportGO:00986621940.022
proteolysis involved in cellular protein catabolic processGO:00516032440.022
regenerationGO:003109940.022
segmentationGO:003528240.021
purine ribonucleotide catabolic processGO:00091544040.021
rna interferenceGO:001624640.021
translationGO:00064121320.021
regulation of immune responseGO:00507762010.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
organic acid transportGO:0015849650.021
regulation of protein complex assemblyGO:00432541470.021
regulation of protein maturationGO:19033171500.021
monocarboxylic acid metabolic processGO:00327871850.021
aspartate family amino acid catabolic processGO:000906850.021
carboxylic acid transportGO:0046942630.021
regulation of ion transportGO:00432691890.021
inorganic ion transmembrane transportGO:00986602310.020
secretionGO:00469032540.020
response to cytokineGO:00340972320.020
cardiovascular system developmentGO:00723582620.020
positive regulation of cellular catabolic processGO:00313312840.020
spinal cord developmentGO:002151040.020
defense responseGO:00069523150.020
anterior posterior axis specificationGO:000994820.020
cell cell signalingGO:00072671550.019
negative regulation of phosphorus metabolic processGO:00105632670.019
biological adhesionGO:00226103310.019
negative regulation of hydrolase activityGO:00513461820.019
receptor metabolic processGO:0043112810.019
organophosphate biosynthetic processGO:00904071630.019
secretion by cellGO:00329402260.019
negative regulation of phosphate metabolic processGO:00459362670.019
endocytosisGO:00068971590.019
cellular homeostasisGO:00197251960.019
immune system developmentGO:00025201950.019
organelle assemblyGO:00709251760.018
innate immune responseGO:00450871780.018
organophosphate catabolic processGO:00464344300.018
regulation of cellular ketone metabolic processGO:0010565500.018
apoptotic mitochondrial changesGO:0008637570.018
tissue regenerationGO:004224630.018
myosin filament assemblyGO:003103420.018
fatty acid transportGO:0015908250.018
neurological system processGO:00508771630.018
transmembrane transportGO:00550853990.018
nucleotide catabolic processGO:00091664080.018
dna catabolic processGO:0006308490.018
metencephalon developmentGO:002203720.018
phototransductionGO:000760230.017
protein tetramerizationGO:0051262470.017
regulation of nucleotide catabolic processGO:00308112050.017
regulation of purine nucleotide catabolic processGO:00331212050.017
angiogenesisGO:00015251470.017
divalent inorganic cation homeostasisGO:00725071360.017
nadh metabolic processGO:000673410.017
negative regulation of cellular protein metabolic processGO:00322693530.017
positive regulation of cellular amine metabolic processGO:003324070.017
regulation of nucleoside metabolic processGO:00091182090.017
cell morphogenesisGO:00009022960.017
nerve developmentGO:002167540.017
lipid transportGO:0006869900.017
membrane organizationGO:00610242920.016
negative regulation of phosphorylationGO:00423261740.016
coenzyme biosynthetic processGO:0009108240.016
nucleoside catabolic processGO:00091644080.016
blastoderm segmentationGO:000735020.016
aspartate metabolic processGO:000653140.016
amino acid activationGO:0043038120.016
cytokine productionGO:00018162470.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.016
single organism membrane organizationGO:00448022680.016
spermatid developmentGO:000728640.016
purine containing compound catabolic processGO:00725234110.016
microtubule based processGO:00070172100.015
protein refoldingGO:0042026140.015
cellular metal ion homeostasisGO:00068751460.015
reproductive processGO:00224141060.015
divalent inorganic cation transportGO:00725111580.015
hemopoiesisGO:00300971800.015
memoryGO:000761330.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of hormone levelsGO:00108171250.015
growthGO:00400072020.015
reproductionGO:0000003630.015
negative regulation of catalytic activityGO:00430863350.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
patterning of blood vesselsGO:000156920.015
organic anion transportGO:00157111030.015
regulation of protein processingGO:00706131500.015
ion homeostasisGO:00508012300.015
Mouse
negative regulation of protein modification processGO:00314002000.014
cytokine mediated signaling pathwayGO:00192211090.014
cell developmentGO:00484683280.014
sleepGO:003043120.014
regulation of purine nucleotide metabolic processGO:19005422640.014
positive regulation of developmental processGO:00510943140.014
cellular component morphogenesisGO:00329893140.014
organic hydroxy compound metabolic processGO:19016151470.014
Mouse
receptor mediated endocytosisGO:0006898840.014
cellular protein catabolic processGO:00442572610.014
small molecule catabolic processGO:0044282920.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
purine nucleoside catabolic processGO:00061523980.014
vasculature developmentGO:00019441810.014
synaptic transmissionGO:0007268610.014
trna aminoacylation for protein translationGO:000641880.014
2 oxoglutarate metabolic processGO:000610340.014
Mouse
nucleoside triphosphate catabolic processGO:00091433940.014
cellular amide metabolic processGO:0043603690.014
monovalent inorganic cation transportGO:00156721280.014
circulatory system developmentGO:00723592620.014
blood vessel developmentGO:00015681720.014
nucleotide biosynthetic processGO:00091651090.014
apoptotic signaling pathwayGO:00971902680.014
negative regulation of proteolysisGO:00458611320.014
locomotory behaviorGO:000762610.014
nicotinamide nucleotide metabolic processGO:0046496140.014
monocarboxylic acid transportGO:0015718320.013
regulation of cell adhesionGO:00301551660.013
regulation of nucleotide metabolic processGO:00061402690.013
purine nucleotide catabolic processGO:00061954050.013
neuron differentiationGO:00301821380.013
dephosphorylationGO:00163112090.013
response to hormoneGO:00097251750.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
ribose phosphate biosynthetic processGO:0046390820.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
one carbon metabolic processGO:000673010.013
generation of neuronsGO:00486991520.013
epithelium developmentGO:00604292270.013
negative regulation of protein metabolic processGO:00512483910.013
regulation of atpase activityGO:0043462250.013
regulation of neural precursor cell proliferationGO:200017740.013
reactive oxygen species metabolic processGO:0072593750.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
purine ribonucleoside triphosphate catabolic processGO:00092073910.013
syncytium formation by plasma membrane fusionGO:000076820.013
cell differentiation in spinal cordGO:002151510.013
regulation of defense responseGO:00313471540.013
response to lipidGO:00339932060.013
divalent metal ion transportGO:00708381520.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
cellular calcium ion homeostasisGO:00068741170.013
ribonucleoside catabolic processGO:00424544060.012
neuroblast proliferationGO:000740540.012
negative regulation of protein maturationGO:19033181420.012
regulation of kinase activityGO:00435493140.012
central nervous system developmentGO:00074171230.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of cell developmentGO:00602841610.012
guanosine containing compound catabolic processGO:19010692390.012
tripartite regional subdivisionGO:000735120.012
apoptotic nuclear changesGO:0030262130.012
cell adhesionGO:00071553250.012
tissue homeostasisGO:0001894630.012
protein homooligomerizationGO:00512601000.012
negative regulation of multicellular organismal processGO:00512413170.012
protein stabilizationGO:0050821640.012
lipid metabolic processGO:00066293810.012
positive regulation of dna metabolic processGO:0051054730.012
negative regulation of cellular amine metabolic processGO:003323930.012
reactive oxygen species biosynthetic processGO:190340940.012
cell activationGO:00017752130.012
nucleoside phosphate catabolic processGO:19012924120.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
multicellular organismal reproductive processGO:0048609400.011
wound healingGO:00420601150.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
metal ion homeostasisGO:00550651690.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
cellular response to oxygen containing compoundGO:19017012760.011
negative regulation of cellular component organizationGO:00511292350.011
internal protein amino acid acetylationGO:00064751010.011
cell projection organizationGO:00300302520.011
homeostasis of number of cellsGO:0048872400.011
ribonucleoside triphosphate catabolic processGO:00092033910.011
negative regulation of protein processingGO:00109551420.011
regulation of cytokine productionGO:00018172320.011
cell growthGO:00160491600.011
glucose metabolic processGO:0006006450.011
positive regulation of mitochondrion organizationGO:0010822300.011
embryo development ending in birth or egg hatchingGO:0009792340.011
purine containing compound biosynthetic processGO:0072522880.011
regulation of cytoskeleton organizationGO:00514931770.011
anatomical structure homeostasisGO:00602491000.011
cellular component disassembly involved in execution phase of apoptosisGO:0006921130.011
reproductive structure developmentGO:0048608550.011
protein catabolic processGO:00301633250.011
head developmentGO:00603221080.011
acetyl coa biosynthetic process from pyruvateGO:000608640.011
myeloid cell differentiationGO:00300991170.011
cation homeostasisGO:00550801890.011
regulation of innate immune responseGO:0045088970.011
ventral spinal cord developmentGO:002151710.011
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.011
cerebellum developmentGO:002154920.010
response to interferon gammaGO:0034341390.010
positive regulation of phosphorylationGO:00423273940.010
negative regulation of transferase activityGO:00513481240.010
positive regulation of cell differentiationGO:00455972110.010
rho protein signal transductionGO:0007266260.010
single organism cellular localizationGO:19025803320.010
response to woundingGO:00096111680.010
positive regulation of immune responseGO:00507781590.010
protein acetylationGO:00064731160.010
oocyte developmentGO:004859910.010
reactive nitrogen species metabolic processGO:200105730.010
striated muscle myosin thick filament assemblyGO:007168820.010

GOT1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.191
inherited metabolic disorderDOID:6552420.191
neuropathyDOID:870520.158
nervous system diseaseDOID:8634310.158
immune system diseaseDOID:29141550.119
neuromuscular diseaseDOID:440380.106
amino acid metabolic disorderDOID:9252500.074
hematopoietic system diseaseDOID:741000.071
central nervous system diseaseDOID:3311860.050
sensory system diseaseDOID:00501552030.046
mitochondrial metabolism diseaseDOID:700290.045
leigh diseaseDOID:3652160.045
coenzyme q10 deficiency diseaseDOID:005073060.040
eye and adnexa diseaseDOID:14921500.029
eye diseaseDOID:56141490.029
neurodegenerative diseaseDOID:12891020.018
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
retinal diseaseDOID:56791180.015
carbohydrate metabolic disorderDOID:2978550.014