Homo sapiens

151 known processes

TOP2A

topoisomerase (DNA) II alpha 170kDa

(Aliases: TOP2,TP2A)

TOP2A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517263930.964
Yeast Fly
sister chromatid segregationGO:0000819540.919
Fly
purine nucleoside monophosphate catabolic processGO:00091281580.910
post embryonic developmentGO:000979120.906
Worm
cellular response to dna damage stimulusGO:00069743790.883
mitotic cell cycleGO:00002783260.880
Yeast Fly
chromatin modificationGO:00165682980.868
Yeast
nucleoside triphosphate metabolic processGO:00091414220.858
ribonucleotide catabolic processGO:00092614050.744
dna conformation changeGO:00711031130.716
negative regulation of cell cycle processGO:00109481210.714
Yeast Fly
purine ribonucleoside monophosphate catabolic processGO:00091691580.691
mitotic sister chromatid segregationGO:0000070530.669
Fly
regulation of cell cycle processGO:00105642660.667
Yeast Fly
atp catabolic processGO:00062001570.662
cell cycle phase transitionGO:00447701730.647
Yeast Fly
mitotic cell cycle processGO:19030472860.612
Yeast Fly
nucleoside triphosphate catabolic processGO:00091433940.597
microtubule cytoskeleton organizationGO:00002261760.592
Fly
regulation of mitotic cell cycleGO:00073461890.583
Yeast Fly
nucleoside monophosphate catabolic processGO:00091251590.535
chromatin assembly or disassemblyGO:0006333780.531
Yeast
negative regulation of cell cycleGO:00457861930.526
Yeast Fly
establishment of organelle localizationGO:0051656590.525
Fly
protein localization to nucleusGO:00345041360.522
regulation of cell cycle phase transitionGO:19019871260.517
Yeast Fly
ribonucleoside monophosphate metabolic processGO:00091611870.517
dna dependent dna replicationGO:0006261440.513
Yeast
mitotic cell cycle phase transitionGO:00447721620.503
Yeast Fly
ribonucleoside catabolic processGO:00424544060.466
nucleoside phosphate catabolic processGO:19012924120.454
cell cycle checkpointGO:00000751170.443
Yeast Fly
nucleoside catabolic processGO:00091644080.413
cellular macromolecular complex assemblyGO:00346223240.412
purine nucleotide catabolic processGO:00061954050.410
neuroblast divisionGO:005505710.399
purine ribonucleoside catabolic processGO:00461303980.384
meiotic chromosome segregationGO:004513240.380
protein catabolic processGO:00301633250.376
spindle stabilizationGO:004314640.365
ribonucleoside triphosphate catabolic processGO:00092033910.358
atp metabolic processGO:00460341760.357
nervous system developmentGO:00073992930.343
purine nucleoside triphosphate catabolic processGO:00091463920.341
nucleoside monophosphate metabolic processGO:00091231910.340
dna recombinationGO:0006310770.332
Yeast
purine nucleoside triphosphate metabolic processGO:00091444120.332
neuroblast proliferationGO:000740540.328
purine nucleoside monophosphate metabolic processGO:00091261860.323
cell divisionGO:00513011680.319
Mouse
mitotic nuclear divisionGO:00070671190.314
Fly
response to abiotic stimulusGO:00096283360.312
cytoskeleton dependent cytokinesisGO:0061640220.297
response to organic cyclic compoundGO:00140702040.291
single organism nuclear importGO:19025931040.285
chromosome condensationGO:0030261150.280
negative regulation of mitotic cell cycle phase transitionGO:1901991850.277
Yeast Fly
cellular protein complex assemblyGO:00436231880.271
negative regulation of cell cycle phase transitionGO:1901988890.261
Yeast Fly
regulation of cell divisionGO:00513021160.244
purine ribonucleoside monophosphate metabolic processGO:00091671860.236
single organism cellular localizationGO:19025803320.234
spindle assembly involved in mitosisGO:0090307120.231
regulation of protein import into nucleusGO:0042306780.228
positive regulation of phosphorylationGO:00423273940.226
meiosis iGO:000712740.225
Yeast
embryo developmentGO:00097901230.220
Mouse Worm
ribonucleoside triphosphate metabolic processGO:00091994120.217
establishment of protein localization to organelleGO:00725941720.211
nucleocytoplasmic transportGO:00069131760.202
glycosyl compound catabolic processGO:19016584130.194
ribonucleoside monophosphate catabolic processGO:00091581580.193
positive regulation of catabolic processGO:00098963100.192
negative regulation of apoptotic processGO:00430663160.186
modification dependent protein catabolic processGO:00199412090.185
nuclear importGO:00511701060.184
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.184
dna packagingGO:0006323770.184
microtubule based processGO:00070172100.183
Fly
oogenesisGO:004847720.182
proteasomal protein catabolic processGO:00104981760.177
centrosome organizationGO:0051297580.170
nuclear divisionGO:00002801280.165
Yeast Fly
spindle elongationGO:005123140.164
covalent chromatin modificationGO:00165692540.162
negative regulation of proteolysisGO:00458611320.162
centrosome separationGO:005129930.161
purine ribonucleotide catabolic processGO:00091544040.157
negative regulation of mitotic cell cycleGO:00459301020.157
Yeast Fly
regulation of mitotic cell cycle phase transitionGO:19019901180.155
Yeast Fly
proteolysis involved in cellular protein catabolic processGO:00516032440.154
protein importGO:00170381300.153
microtubule polymerization or depolymerizationGO:0031109370.151
purine ribonucleoside triphosphate catabolic processGO:00092073910.150
generation of neuronsGO:00486991520.148
regulation of protein localizationGO:00328802960.148
organelle assemblyGO:00709251760.145
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.144
regulation of cellular response to stressGO:00801352440.143
negative regulation of cellular component organizationGO:00511292350.140
growthGO:00400072020.140
blastocyst developmentGO:000182430.139
regulation of wnt signaling pathwayGO:00301111230.139
male gonad developmentGO:0008584230.133
metaphase plate congressionGO:0051310180.131
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.129
regulation of nucleocytoplasmic transportGO:0046822980.129
sex differentiationGO:0007548450.129
regulation of mitotic sister chromatid segregationGO:0033047270.128
actin cytoskeleton organizationGO:00300362070.127
regulation of proteasomal protein catabolic processGO:0061136870.127
protein targeting to nucleusGO:00447441040.126
regulation of chromosome segregationGO:0051983440.124
establishment of nucleus localizationGO:004002310.124
purine containing compound catabolic processGO:00725234110.119
regulation of viral processGO:00507921030.117
cell developmentGO:00484683280.116
neurogenesisGO:00220081690.116
nucleus localizationGO:005164710.116
ubiquitin dependent protein catabolic processGO:00065112060.115
regulation of dna metabolic processGO:00510521530.115
organelle localizationGO:0051640840.114
Fly
circulatory system developmentGO:00723592620.114
regulation of cell developmentGO:00602841610.113
modification dependent macromolecule catabolic processGO:00436322120.112
cytokinesisGO:0000910960.112
protein targetingGO:00066051870.111
nucleotide catabolic processGO:00091664080.109
negative regulation of cell deathGO:00605483450.108
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.108
regulation of proteolysisGO:00301622930.107
cellular response to endogenous stimulusGO:00714953360.107
cellular macromolecule catabolic processGO:00442653800.105
cellular component morphogenesisGO:00329893140.104
spindle organizationGO:0007051530.104
Fly
cardiovascular system developmentGO:00723582620.104
positive regulation of protein transportGO:00512221350.103
double strand break repairGO:00063021010.103
positive regulation of cell cycleGO:00457871400.100
positive regulation of intracellular transportGO:00323881040.099
regulation of protein catabolic processGO:00421761550.099
regenerationGO:003109940.098
Zebrafish
protein dna complex subunit organizationGO:0071824800.098
dna ligationGO:0006266100.098
maintenance of locationGO:00512351120.097
purine nucleoside catabolic processGO:00061523980.095
protein import into nucleusGO:00066061040.094
muscle organ developmentGO:0007517560.093
chromatin organizationGO:00063253510.093
Yeast
regulation of protein targetingGO:1903533910.092
wnt signaling pathwayGO:00160551560.090
positive regulation of protein phosphorylationGO:00019343130.090
hematopoietic or lymphoid organ developmentGO:00485341860.086
Mouse
mitotic centrosome separationGO:000710010.086
positive regulation of organelle organizationGO:00106381950.085
positive regulation of developmental processGO:00510943140.084
immune system developmentGO:00025201950.083
Mouse
meiotic nuclear divisionGO:0007126100.082
Yeast
mitotic spindle elongationGO:000002240.082
dna repairGO:00062811980.081
response to oxygen containing compoundGO:19017003690.079
response to oxygen levelsGO:00704821000.078
cellular response to oxygen containing compoundGO:19017012760.078
positive regulation of wnt signaling pathwayGO:0030177540.078
positive regulation of cellular component organizationGO:00511303760.077
regulation of protein complex assemblyGO:00432541470.077
positive regulation of cell cycle processGO:00900681060.076
response to organonitrogen compoundGO:00102431560.076
nuclear transportGO:00511691790.075
positive regulation of cell proliferationGO:00082843010.074
chemotaxisGO:00069351570.073
mitotic cell cycle checkpointGO:0007093680.072
Yeast Fly
signal transduction by phosphorylationGO:00230142970.072
organophosphate catabolic processGO:00464344300.072
female gamete generationGO:000729220.071
hemopoiesisGO:00300971800.071
Mouse
positive regulation of intracellular protein transportGO:0090316760.071
stem cell differentiationGO:0048863930.070
regulation of protein localization to nucleusGO:1900180850.069
chromosome separationGO:0051304230.069
viral processGO:00160321460.068
cell projection organizationGO:00300302520.067
mitotic sister chromatid separationGO:0051306180.066
regulation of cytoplasmic transportGO:19036491490.066
organ morphogenesisGO:00098871470.065
locomotory behaviorGO:000762610.064
reproductive structure developmentGO:0048608550.064
dna replicationGO:00062601160.064
Yeast
regulation of cytoskeleton organizationGO:00514931770.063
myeloid cell differentiationGO:00300991170.063
chromosome segregationGO:00070591140.060
regulation of establishment of protein localizationGO:00702012420.060
response to lipidGO:00339932060.059
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.058
organelle fissionGO:00482851490.058
Yeast Fly
regulation of cell differentiationGO:00455953930.057
chromatin remodelingGO:0006338550.057
Yeast
anatomical structure formation involved in morphogenesisGO:00486462840.057
reciprocal dna recombinationGO:003582540.056
Yeast
cell morphogenesisGO:00009022960.056
intrinsic apoptotic signaling pathwayGO:00971931270.055
maintenance of location in cellGO:0051651620.055
multi organism cellular processGO:00447641560.055
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.054
nuclear migrationGO:000709710.054
intracellular protein transportGO:00068862700.054
regulation of protein processingGO:00706131500.054
regulation of response to dna damage stimulusGO:2001020940.054
regulation of cellular component movementGO:00512703340.053
positive regulation of cytoplasmic transportGO:1903651820.053
regulation of mitosisGO:0007088630.053
ras protein signal transductionGO:0007265730.053
angiogenesisGO:00015251470.052
purine ribonucleoside metabolic processGO:00461284370.051
single organism reproductive processGO:0044702980.051
histone modificationGO:00165702510.051
mitotic spindle organizationGO:0007052270.050
Fly
macromolecule methylationGO:0043414970.050
negative regulation of cell differentiationGO:00455961710.050
nucleus organizationGO:0006997280.050
regulation of intracellular protein transportGO:00331571230.050
neuron differentiationGO:00301821380.048
regulation of bindingGO:00510981110.048
determination of adult lifespanGO:000834020.048
kinetochore organizationGO:005138380.048
positive regulation of proteolysisGO:00458621420.047
protein localization to organelleGO:00333652800.047
positive regulation of cell developmentGO:0010720920.047
cell part morphogenesisGO:00329901370.047
mitotic cytokinesisGO:0000281190.047
response to nitrogen compoundGO:19016981840.047
positive regulation of protein import into nucleusGO:0042307460.046
negative regulation of programmed cell deathGO:00430693210.046
regulation of gene expression epigeneticGO:0040029730.046
Worm Fly
negative regulation of organelle organizationGO:00106391260.045
dna ligation involved in dna repairGO:005110340.045
gland developmentGO:0048732480.045
protein depolymerizationGO:0051261300.045
cell projection morphogenesisGO:00488581290.044
protein processingGO:00164852260.043
response to oxidative stressGO:00069791210.043
response to hormoneGO:00097251750.042
cytoplasmic transportGO:00164823790.042
mitotic spindle midzone assemblyGO:005125640.041
dephosphorylationGO:00163112090.041
positive regulation of programmed cell deathGO:00430682490.041
regulation of nervous system developmentGO:0051960880.041
microtubule anchoringGO:0034453240.040
negative regulation of protein metabolic processGO:00512483910.040
small gtpase mediated signal transductionGO:0007264780.040
sister chromatid biorientationGO:003113420.039
development of primary male sexual characteristicsGO:0046546230.039
epithelium developmentGO:00604292270.039
chordate embryonic developmentGO:0043009340.039
regulation of microtubule polymerization or depolymerizationGO:0031110270.039
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.038
regulation of protein transportGO:00512232130.038
heart developmentGO:0007507950.038
regulation of mitotic metaphase anaphase transitionGO:0030071260.038
oocyte developmentGO:004859910.038
protein polymerizationGO:0051258710.037
regulation of transferase activityGO:00513383550.037
cell morphogenesis involved in differentiationGO:00009041440.037
spindle checkpointGO:0031577260.037
response to alcoholGO:0097305640.036
enzyme linked receptor protein signaling pathwayGO:00071673030.036
mitotic dna integrity checkpointGO:0044774300.036
Yeast Fly
regulation of microtubule based processGO:0032886740.036
developmental process involved in reproductionGO:0003006660.036
microtubule based movementGO:0007018320.035
methylationGO:00322591060.035
tissue morphogenesisGO:0048729960.035
actin filament based processGO:00300292240.035
response to radiationGO:00093141510.035
regulation of kinase activityGO:00435493140.034
stem cell divisionGO:001714520.034
protein maturationGO:00516042330.034
regulation of sequence specific dna binding transcription factor activityGO:00510902110.033
multicellular organismal agingGO:001025930.033
taxisGO:00423301570.033
positive regulation of cellular catabolic processGO:00313312840.033
positive regulation of protein kinase activityGO:00458601900.032
regulation of protein kinase activityGO:00458592890.032
neuron projection morphogenesisGO:0048812500.032
response to uvGO:0009411730.032
maintenance of protein locationGO:0045185570.031
neuron developmentGO:00486661130.031
regulation of cell motilityGO:20001452990.031
positive regulation of neural precursor cell proliferationGO:200017920.031
forebrain developmentGO:0030900260.031
negative regulation of developmental processGO:00510932470.031
response to hypoxiaGO:0001666960.031
regulation of cellular component biogenesisGO:00440872810.031
regulation of cell migrationGO:00303342890.031
response to other organismGO:00517072610.030
maintenance of protein location in cellGO:0032507560.030
gene silencingGO:0016458490.030
Worm Fly
peptidyl tyrosine phosphorylationGO:00181081700.030
spindle midzone assemblyGO:005125540.030
response to light stimulusGO:0009416870.029
regulation of myeloid cell differentiationGO:0045637810.029
negative regulation of protein maturationGO:19033181420.029
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.029
cellular response to external stimulusGO:00714961110.029
regulation of intracellular transportGO:00323861950.028
brain developmentGO:0007420970.028
regulation of neurogenesisGO:0050767820.028
head developmentGO:00603221080.028
mitotic chromosome condensationGO:0007076110.028
Fly
base excision repairGO:0006284210.027
mapk cascadeGO:00001652880.027
negative regulation of cell divisionGO:0051782310.027
positive regulation of hydrolase activityGO:00513453310.027
mitotic spindle checkpointGO:0071174180.027
response to woundingGO:00096111680.027
cellular component disassemblyGO:0022411920.027
cellular protein catabolic processGO:00442572610.026
positive regulation of cell deathGO:00109422630.026
negative regulation of multicellular organismal processGO:00512413170.026
positive regulation of transportGO:00510503360.026
endomembrane system organizationGO:00102561960.025
regulation of epithelial cell proliferationGO:00506781130.025
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.025
response to drugGO:0042493810.025
eye photoreceptor cell differentiationGO:000175420.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
blood vessel morphogenesisGO:00485141620.025
embryo development ending in birth or egg hatchingGO:0009792340.025
Worm
spindle assemblyGO:0051225290.024
apoptotic signaling pathwayGO:00971902680.024
oocyte differentiationGO:000999420.024
regulation of dna bindingGO:0051101370.024
dna damage checkpointGO:0000077680.024
Fly
response to steroid hormoneGO:0048545800.024
positive regulation of cell differentiationGO:00455972110.024
reproductive processGO:00224141060.024
double strand break repair via nonhomologous end joiningGO:0006303100.024
negative regulation of chromosome organizationGO:2001251480.024
microtubule cytoskeleton organization involved in mitosisGO:1902850150.023
regulation of multi organism processGO:00439001570.023
protein homooligomerizationGO:00512601000.023
positive regulation of nucleocytoplasmic transportGO:0046824540.023
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063330.023
positive regulation of protein localization to nucleusGO:1900182480.022
cellular amino acid metabolic processGO:00065201160.022
cellular response to hormone stimulusGO:00328701250.022
positive regulation of mitosisGO:0045840250.022
male meiosisGO:000714010.022
regulation of protein stabilityGO:0031647870.022
regulation of microtubule cytoskeleton organizationGO:0070507610.021
vasculature developmentGO:00019441810.021
regulation of locomotionGO:00400123290.021
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.021
regulation of cell morphogenesisGO:00226041530.021
membrane organizationGO:00610242920.020
negative regulation of nervous system developmentGO:0051961280.020
response to biotic stimulusGO:00096072760.020
regulation of nuclear divisionGO:0051783650.020
non recombinational repairGO:0000726140.020
negative regulation of phosphorus metabolic processGO:00105632670.020
developmental growthGO:0048589480.020
reproductionGO:0000003630.020
Yeast Worm
regulation of protein serine threonine kinase activityGO:00719001790.020
regulation of peptidase activityGO:00525471800.020
microtubule organizing center organizationGO:0031023620.020
brain morphogenesisGO:004885410.019
development of primary sexual characteristicsGO:0045137350.019
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.019
regulation of defense responseGO:00313471540.019
regulation of dna replicationGO:0006275680.019
Yeast
positive regulation of multi organism processGO:0043902560.019
somatic stem cell divisionGO:004810310.019
positive regulation of mitotic cell cycleGO:0045931600.019
cell fate determinationGO:000170930.019
spermatid differentiationGO:004851540.019
response to purine containing compoundGO:0014074400.019
v d j recombinationGO:003315130.018
tissue regenerationGO:004224630.018
regulation of double strand break repairGO:2000779220.018
nucleic acid phosphodiester bond hydrolysisGO:00903051020.018
protein autophosphorylationGO:00467771230.018
dna geometric changeGO:0032392320.018
Yeast
positive regulation of protein catabolic processGO:0045732750.018
regulation of response to external stimulusGO:00321012220.018
regulation of dephosphorylationGO:0035303960.018
negative regulation of intracellular signal transductionGO:19025321830.018
negative regulation of phosphate metabolic processGO:00459362670.018
negative regulation of cellular protein metabolic processGO:00322693530.018
cellular amine metabolic processGO:0044106410.018
regulation of spindle organizationGO:0090224100.018
regulation of cellular ketone metabolic processGO:0010565500.018
regulation of sister chromatid segregationGO:0033045270.017
negative regulation of catalytic activityGO:00430863350.017
response to external biotic stimulusGO:00432072610.017
regulation of cell adhesionGO:00301551660.017
reproductive system developmentGO:0061458560.017
epithelial cell differentiationGO:00308551410.017
hematopoietic progenitor cell differentiationGO:0002244380.016
Mouse
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.016
cellular response to lipidGO:00713961270.016
neuron projection developmentGO:00311751060.016
signal transduction involved in regulation of gene expressionGO:002301910.016
regulation of cellular amino acid metabolic processGO:000652160.016
positive regulation of myeloid cell differentiationGO:0045639390.016
regulation of ras protein signal transductionGO:00465781550.016
muscle tissue developmentGO:0060537620.016
regulation of canonical wnt signaling pathwayGO:0060828880.016
positive regulation of dna metabolic processGO:0051054730.016
regulation of mitotic recombinationGO:000001910.016
Yeast
positive regulation of cell divisionGO:0051781590.016
cell cycle g2 m phase transitionGO:0044839430.016
response to nutrient levelsGO:0031667810.016
spermatid developmentGO:000728640.015
single organism carbohydrate metabolic processGO:00447231930.015
dna integrity checkpointGO:0031570710.015
Yeast Fly
regulation of cellular protein catabolic processGO:1903362960.015
positive regulation of immune responseGO:00507781590.015
stem cell developmentGO:0048864690.015
regulation of protein maturationGO:19033171500.015
regulation of neuron differentiationGO:0045664700.015
central nervous system developmentGO:00074171230.015
response to extracellular stimulusGO:0009991850.015
positive regulation of nervous system developmentGO:0051962540.015
negative regulation of gene expression epigeneticGO:0045814190.014
Fly
cell growthGO:00160491600.014
immune responseGO:00069553070.014
macromolecular complex disassemblyGO:0032984600.014
viral life cycleGO:00190581320.014
wound healingGO:00420601150.014
regulation of immune responseGO:00507762010.014
mesenchymal cell developmentGO:0014031500.014
negative regulation of protein phosphorylationGO:00019331400.014
cellular response to nitrogen compoundGO:19016991440.014
protein complex disassemblyGO:0043241520.014
cellular response to organonitrogen compoundGO:00714171240.014
morphogenesis of an epitheliumGO:0002009600.013
positive regulation of immune system processGO:00026842830.013
negative regulation of protein complex disassemblyGO:0043242200.013
striated muscle tissue developmentGO:0014706590.013
negative regulation of protein catabolic processGO:0042177590.013
protein ubiquitinationGO:00165673140.013
cellular response to extracellular stimulusGO:0031668720.013
cytokinesis completion of separationGO:000710930.013
neuronal stem cell divisionGO:003644510.013
secretion by cellGO:00329402260.013
positive regulation of proteasomal protein catabolic processGO:1901800350.013
positive regulation of kinase activityGO:00336742040.013
negative regulation of transportGO:00510511760.013
cellular protein complex disassemblyGO:0043624360.013
response to axon injuryGO:004867810.013
negative regulation of multi organism processGO:0043901920.013
posttranscriptional regulation of gene expressionGO:00106082130.012
Worm
response to inorganic substanceGO:00100351270.012
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.012
regulation of mitotic spindle organizationGO:006023660.012
regulation of dna repairGO:0006282470.012
positive regulation of chromosome organizationGO:2001252410.012
epithelial cell proliferationGO:00506731280.012
regulation of chromatin modificationGO:1903308510.012
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
ventricular cardiac muscle cell differentiationGO:005501210.012
inflammatory responseGO:0006954790.012
embryonic placenta developmentGO:000189210.012
cytokinetic processGO:0032506120.012
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.012
positive regulation of nucleotide catabolic processGO:00308131850.012
meiotic cell cycleGO:0051321130.011
Yeast
positive regulation of apoptotic processGO:00430652460.011
regulation of mitotic sister chromatid separationGO:0010965270.011
g2 m transition of mitotic cell cycleGO:0000086410.011
ribosome assemblyGO:004225590.011
cell activation involved in immune responseGO:0002263300.011
ossificationGO:00015031210.011
regulation of metaphase anaphase transition of cell cycleGO:1902099260.011
cellular ketone metabolic processGO:0042180800.011
negative regulation of protein processingGO:00109551420.011
establishment or maintenance of cell polarityGO:0007163310.011
mitotic spindle assembly checkpointGO:0007094140.011
somatic diversification of immune receptors via somatic mutationGO:000256610.011
regulation of apoptotic signaling pathwayGO:20012331750.011
attachment of spindle microtubules to kinetochoreGO:0008608170.011
positive regulation of transferase activityGO:00513472270.011
multi organism reproductive processGO:0044703540.011
circulatory system processGO:00030131130.011
symbiosis encompassing mutualism through parasitismGO:00444031560.010
positive regulation of protein complex assemblyGO:0031334860.010
lipid catabolic processGO:0016042840.010
response to growth factorGO:00708482050.010
cellular response to oxidative stressGO:0034599850.010
regulation of purine nucleotide metabolic processGO:19005422640.010
centrosome cycleGO:0007098320.010
cellular response to reactive oxygen speciesGO:0034614500.010

TOP2A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.160
cancerDOID:1621670.074
organ system cancerDOID:00506861640.074
thoracic cancerDOID:5093210.016
physical disorderDOID:0080015410.016
breast cancerDOID:1612210.012