Homo sapiens

7 known processes

ERAP2

endoplasmic reticulum aminopeptidase 2

(Aliases: FLJ23807,FLJ23701,L-RAP,FLJ23633,LRAP)

ERAP2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.068
immune responseGO:00069553070.050
positive regulation of transportGO:00510503360.045
cellular ketone metabolic processGO:0042180800.045
regulation of establishment of protein localizationGO:00702012420.043
determination of adult lifespanGO:000834020.043
multicellular organismal agingGO:001025930.041
regulation of protein localizationGO:00328802960.041
cellular amino acid metabolic processGO:00065201160.040
regulation of cellular amino acid metabolic processGO:000652160.039
amine metabolic processGO:0009308440.038
purine ribonucleotide catabolic processGO:00091544040.038
regulation of cellular amine metabolic processGO:0033238110.037
nucleotide catabolic processGO:00091664080.037
defense responseGO:00069523150.037
purine ribonucleoside metabolic processGO:00461284370.036
cellular amine metabolic processGO:0044106410.036
transmembrane transportGO:00550853990.036
organophosphate catabolic processGO:00464344300.036
regulation of cellular ketone metabolic processGO:0010565500.036
purine nucleotide catabolic processGO:00061954050.036
female gamete generationGO:000729220.036
ribonucleoside triphosphate catabolic processGO:00092033910.035
cytokine productionGO:00018162470.035
oogenesisGO:004847720.035
positive regulation of immune system processGO:00026842830.035
purine nucleoside triphosphate catabolic processGO:00091463920.035
regulation of protein transportGO:00512232130.034
positive regulation of hydrolase activityGO:00513453310.034
glycosyl compound catabolic processGO:19016584130.033
regulation of cytokine productionGO:00018172320.033
purine ribonucleoside catabolic processGO:00461303980.033
ribonucleoside catabolic processGO:00424544060.033
nucleoside triphosphate metabolic processGO:00091414220.033
purine containing compound catabolic processGO:00725234110.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
purine nucleoside triphosphate metabolic processGO:00091444120.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.032
nucleoside phosphate catabolic processGO:19012924120.032
ribonucleotide catabolic processGO:00092614050.031
negative regulation of protein metabolic processGO:00512483910.031
nucleoside catabolic processGO:00091644080.031
locomotory behaviorGO:000762610.030
regulation of proteolysisGO:00301622930.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
purine ribonucleoside triphosphate metabolic processGO:00092054110.030
nucleoside triphosphate catabolic processGO:00091433940.030
positive regulation of phosphorylationGO:00423273940.029
cytoplasmic transportGO:00164823790.029
positive regulation of catabolic processGO:00098963100.029
purine nucleoside catabolic processGO:00061523980.029
negative regulation of cellular protein metabolic processGO:00322693530.028
response to external biotic stimulusGO:00432072610.028
Human
cellular macromolecule catabolic processGO:00442653800.028
response to other organismGO:00517072610.028
Human
secretion by cellGO:00329402260.028
secretionGO:00469032540.028
biological adhesionGO:00226103310.028
single organism cellular localizationGO:19025803320.027
ras protein signal transductionGO:0007265730.027
cellular response to dna damage stimulusGO:00069743790.027
positive regulation of cellular amine metabolic processGO:003324070.027
apoptotic signaling pathwayGO:00971902680.027
protein catabolic processGO:00301633250.027
regulation of secretionGO:00510461940.026
positive regulation of cell proliferationGO:00082843010.026
positive regulation of cellular component organizationGO:00511303760.026
positive regulation of cytokine productionGO:00018191670.026
lipid metabolic processGO:00066293810.026
neuromuscular junction developmentGO:000752830.026
small gtpase mediated signal transductionGO:0007264780.026
ion transmembrane transportGO:00342203380.025
response to abiotic stimulusGO:00096283360.025
regulation of cell cycleGO:00517263930.025
intracellular protein transportGO:00068862700.025
mitotic cell cycleGO:00002783260.025
response to oxygen containing compoundGO:19017003690.025
regulation of immune responseGO:00507762010.025
vesicle mediated transportGO:00161923710.025
segmentationGO:003528240.025
proteolysis involved in cellular protein catabolic processGO:00516032440.025
activation of immune responseGO:00022531140.025
positive regulation of protein transportGO:00512221350.024
negative regulation of catalytic activityGO:00430863350.024
regulation of locomotionGO:00400123290.024
immune response activating signal transductionGO:0002757900.024
cell activationGO:00017752130.024
gtp metabolic processGO:00460392390.024
positive regulation of cellular catabolic processGO:00313312840.024
positive regulation of secretionGO:00510471160.024
regulation of secretion by cellGO:19035301770.024
regulation of cellular component movementGO:00512703340.023
protein maturationGO:00516042330.023
regulation of transferase activityGO:00513383550.023
cellular protein catabolic processGO:00442572610.023
negative regulation of phosphate metabolic processGO:00459362670.023
multi organism cellular processGO:00447641560.023
system processGO:00030083490.023
Human
regulation of cellular component biogenesisGO:00440872810.023
guanosine containing compound catabolic processGO:19010692390.022
innate immune responseGO:00450871780.022
gtp catabolic processGO:00061842370.022
protein localization to organelleGO:00333652800.022
mapk cascadeGO:00001652880.022
protein processingGO:00164852260.022
regulation of response to external stimulusGO:00321012220.022
regulation of nucleotide metabolic processGO:00061402690.022
cellular lipid metabolic processGO:00442553030.022
negative regulation of phosphorus metabolic processGO:00105632670.022
inorganic ion transmembrane transportGO:00986602310.022
positive regulation of immune responseGO:00507781590.022
regulation of purine nucleotide metabolic processGO:19005422640.022
rho protein signal transductionGO:0007266260.021
leukocyte activationGO:00453211640.021
memoryGO:000761330.021
immune effector processGO:00022521590.021
signal transduction by phosphorylationGO:00230142970.021
regulation of cell cycle processGO:00105642660.021
regulation of cell differentiationGO:00455953930.021
single organism membrane organizationGO:00448022680.021
cation transportGO:00068123310.021
guanosine containing compound metabolic processGO:19010682440.021
cation transmembrane transportGO:00986552380.020
cell adhesionGO:00071553250.020
response to biotic stimulusGO:00096072760.020
Human
negative regulation of multicellular organismal processGO:00512413170.020
negative regulation of programmed cell deathGO:00430693210.020
blastoderm segmentationGO:000735020.020
positive regulation of secretion by cellGO:19035321080.020
cellular component morphogenesisGO:00329893140.020
cellular macromolecular complex assemblyGO:00346223240.020
mitotic cell cycle processGO:19030472860.020
actin filament based processGO:00300292240.020
rhythmic behaviorGO:000762220.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
cell morphogenesisGO:00009022960.020
regulation of cell motilityGO:20001452990.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
maintenance of locationGO:00512351120.020
positive regulation of developmental processGO:00510943140.020
regulation of kinase activityGO:00435493140.020
regenerationGO:003109940.019
carbohydrate derivative biosynthetic processGO:19011372070.019
protein modification by small protein conjugationGO:00324463420.019
nervous system developmentGO:00073992930.019
positive regulation of mapk cascadeGO:00434101900.019
membrane organizationGO:00610242920.019
nitrogen compound transportGO:00717051910.019
regulation of protein secretionGO:0050708860.019
regulation of anatomical structure morphogenesisGO:00226032860.019
regulation of multi organism processGO:00439001570.019
negative regulation of apoptotic processGO:00430663160.019
protein secretionGO:0009306980.019
immune response regulating signaling pathwayGO:0002764970.019
protein ubiquitinationGO:00165673140.019
negative regulation of cell proliferationGO:00082852280.019
negative regulation of cell deathGO:00605483450.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
chemical homeostasisGO:00488783060.018
regulation of cell migrationGO:00303342890.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
regulation of i kappab kinase nf kappab signalingGO:00431221620.018
circadian behaviorGO:004851220.018
adult locomotory behaviorGO:000834410.018
compound eye developmentGO:004874910.018
oocyte differentiationGO:000999420.018
regulation of nucleoside metabolic processGO:00091182090.018
i kappab kinase nf kappab signalingGO:00072491660.018
protein targetingGO:00066051870.018
regulation of intracellular transportGO:00323861950.018
activation of innate immune responseGO:0002218550.018
viral processGO:00160321460.018
negative regulation of cellular component organizationGO:00511292350.018
inorganic cation transmembrane transportGO:00986621940.018
oocyte developmentGO:004859910.018
regulation of mapk cascadeGO:00434082620.017
positive regulation of cell deathGO:00109422630.017
cell projection organizationGO:00300302520.017
cellular response to endogenous stimulusGO:00714953360.017
regulation of purine nucleotide catabolic processGO:00331212050.017
organonitrogen compound biosynthetic processGO:19015662000.017
positive regulation of protein phosphorylationGO:00019343130.017
spermatid differentiationGO:004851540.017
release of cytoplasmic sequestered nf kappabGO:000858840.017
regulation of peptidase activityGO:00525471800.017
anterior posterior axis specificationGO:000994820.017
oxidation reduction processGO:00551143960.017
negative regulation of intracellular signal transductionGO:19025321830.017
regulation of nucleotide catabolic processGO:00308112050.017
regulation of leukocyte activationGO:00026941150.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
interspecies interaction between organismsGO:00444191560.017
regulation of cellular response to stressGO:00801352440.017
chromatin organizationGO:00063253510.017
nucleocytoplasmic transportGO:00069131760.017
peripheral nervous system developmentGO:000742220.017
anion transportGO:00068201610.017
positive regulation of apoptotic processGO:00430652460.017
positive regulation of cell differentiationGO:00455972110.017
endomembrane system organizationGO:00102561960.016
regulation of protein processingGO:00706131500.016
regulation of apoptotic signaling pathwayGO:20012331750.016
positive regulation of nucleotide metabolic processGO:00459812300.016
ion homeostasisGO:00508012300.016
negative regulation of cellular amine metabolic processGO:003323930.016
posttranscriptional regulation of gene expressionGO:00106082130.016
metal ion transportGO:00300012720.016
ubiquitin dependent protein catabolic processGO:00065112060.016
morphogenesis of embryonic epitheliumGO:001633140.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
dephosphorylationGO:00163112090.016
spermatid developmentGO:000728640.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
cardiac muscle cell contractionGO:008600340.016
positive regulation of nucleoside metabolic processGO:00459791860.016
response to cytokineGO:00340972320.016
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.016
cellular homeostasisGO:00197251960.016
lipid biosynthetic processGO:00086101770.016
single organism carbohydrate metabolic processGO:00447231930.016
negative regulation of protein modification processGO:00314002000.016
regulation of endopeptidase activityGO:00525481700.016
syncytium formation by plasma membrane fusionGO:000076820.016
regulation of synaptic plasticityGO:004816730.016
cell developmentGO:00484683280.016
negative regulation of cell cycleGO:00457861930.016
negative regulation of hydrolase activityGO:00513461820.015
viral life cycleGO:00190581320.015
modification dependent protein catabolic processGO:00199412090.015
regulation of interleukin 10 secretionGO:200117940.015
lymphocyte activationGO:00466491330.015
nuclear transportGO:00511691790.015
regulation of protein kinase activityGO:00458592890.015
cellular response to oxygen containing compoundGO:19017012760.015
neuroblast proliferationGO:000740540.015
positive regulation of nucleotide catabolic processGO:00308131850.015
negative regulation of transportGO:00510511760.015
regulation of protein catabolic processGO:00421761550.015
cell cycle phase transitionGO:00447701730.015
establishment of protein localization to organelleGO:00725941720.015
positive regulation of programmed cell deathGO:00430682490.015
regulation of mitotic cell cycleGO:00073461890.015
matingGO:000761810.015
covalent chromatin modificationGO:00165692540.015
tripartite regional subdivisionGO:000735120.015
organ formationGO:004864530.015
regulation of gtpase activityGO:00430871800.015
small molecule biosynthetic processGO:00442831570.015
motor neuron axon guidanceGO:000804520.015
inner ear morphogenesisGO:004247240.015
positive regulation of transferase activityGO:00513472270.015
carbohydrate metabolic processGO:00059752070.015
regulation of gtp catabolic processGO:00331241800.015
neurotransmitter secretionGO:000726940.015
regulation of cell activationGO:00508651250.015
protein localization to membraneGO:00726571600.015
cardiovascular system developmentGO:00723582620.015
reactive oxygen species metabolic processGO:0072593750.015
regulation of cytokine secretionGO:0050707570.014
detection of muramyl dipeptideGO:003249810.014
actin filament based movementGO:0030048170.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
histone modificationGO:00165702510.014
nucleoside monophosphate metabolic processGO:00091231910.014
negative regulation of protein processingGO:00109551420.014
anterior posterior axis specification embryoGO:000859520.014
embryonic epithelial tube formationGO:000183840.014
positive regulation of synaptic transmissionGO:005080640.014
positive regulation of cellular component biogenesisGO:00440891580.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
microtubule based processGO:00070172100.014
defense response to other organismGO:00985421290.014
cell fate determinationGO:000170930.014
negative regulation of phosphorylationGO:00423261740.014
rna interferenceGO:001624640.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
salivary gland morphogenesisGO:000743540.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
cation homeostasisGO:00550801890.014
rna processingGO:00063962550.014
protein oligomerizationGO:00512591730.014
regulation of cytoplasmic transportGO:19036491490.014
regulation of innate immune responseGO:0045088970.014
chromatin modificationGO:00165682980.014
proteasomal protein catabolic processGO:00104981760.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
cell growthGO:00160491600.014
positive regulation of protein secretionGO:0050714600.014
organelle assemblyGO:00709251760.014
sequestering of metal ionGO:0051238240.014
negative regulation of developmental processGO:00510932470.014
positive regulation of proteolysisGO:00458621420.014
monocarboxylic acid metabolic processGO:00327871850.014
response to axon injuryGO:004867810.013
mitotic cell cycle phase transitionGO:00447721620.013
stem cell divisionGO:001714520.013
regulation of cytoskeleton organizationGO:00514931770.013
endosomal transportGO:00161971290.013
associative learningGO:000830610.013
cellular protein complex assemblyGO:00436231880.013
cytokine secretionGO:0050663640.013
actin mediated cell contractionGO:0070252120.013
regulation of neural precursor cell proliferationGO:200017740.013
positive regulation of gtpase activityGO:00435471660.013
positive regulation of kinase activityGO:00336742040.013
specification of organ identityGO:001009230.013
reactive oxygen species biosynthetic processGO:190340940.013
circulatory system developmentGO:00723592620.013
divalent metal ion transportGO:00708381520.013
angiogenesisGO:00015251470.013
modification dependent macromolecule catabolic processGO:00436322120.013
metencephalon developmentGO:002203720.013
hindbrain developmentGO:003090230.013
cellular response to abiotic stimulusGO:00712141170.013
neurological system processGO:00508771630.013
regulation of intracellular protein transportGO:00331571230.013
negative regulation of protein maturationGO:19033181420.013
atp metabolic processGO:00460341760.013
cellular cation homeostasisGO:00300031630.013
limbic system developmentGO:002176130.013
morphogenesis of a polarized epitheliumGO:000173830.013
organic acid biosynthetic processGO:0016053970.013
regulation of cell cycle phase transitionGO:19019871260.013
regulation of ras gtpase activityGO:00323181280.013
cellular response to growth factor stimulusGO:00713631970.013
regulation of cell adhesionGO:00301551660.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
positive regulation of leukocyte activationGO:0002696800.013
regulation of defense responseGO:00313471540.013
visual behaviorGO:000763220.013
developmental programmed cell deathGO:001062330.013
response to radiationGO:00093141510.013
negative regulation of immune system processGO:00026831360.012
organophosphate biosynthetic processGO:00904071630.012
response to lipidGO:00339932060.012
reactive nitrogen species metabolic processGO:200105730.012
blood vessel morphogenesisGO:00485141620.012
positive regulation of gtp catabolic processGO:00331261660.012
response to woundingGO:00096111680.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
carboxylic acid biosynthetic processGO:0046394970.012
positive regulation of defense responseGO:0031349870.012
copulationGO:000762010.012
epithelium developmentGO:00604292270.012
organic hydroxy compound metabolic processGO:19016151470.012
microtubule cytoskeleton organizationGO:00002261760.012
cellular response to cytokine stimulusGO:00713451810.012
positive regulation of interleukin 10 secretionGO:200118120.012
wnt signaling pathwayGO:00160551560.012
dna repairGO:00062811980.012
response to growth factorGO:00708482050.012
actin cytoskeleton organizationGO:00300362070.012
growthGO:00400072020.012
divalent inorganic cation transportGO:00725111580.012
positive regulation of organelle organizationGO:00106381950.012
nucleoside monophosphate catabolic processGO:00091251590.012
glycoprotein metabolic processGO:00091001100.012
midgut developmentGO:000749410.012
negative regulation of proteolysisGO:00458611320.012
regulation of bindingGO:00510981110.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
t cell differentiation in thymusGO:003307740.012
cell projection assemblyGO:00300311260.012
t cell activationGO:0042110990.012
response to organic cyclic compoundGO:00140702040.012
protein localization to nucleusGO:00345041360.012
epithelial cell differentiationGO:00308551410.012
single organism cell adhesionGO:00986021790.012
circadian sleep wake cycle processGO:002241020.012
positive regulation of cytokine secretionGO:0050715420.012
somatic stem cell divisionGO:004810310.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
lung alveolus developmentGO:004828640.012
regulation of protein maturationGO:19033171500.012
cell part morphogenesisGO:00329901370.012
regulation of ras protein signal transductionGO:00465781550.012
tissue regenerationGO:004224630.012
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.012
cell divisionGO:00513011680.012
protein modification by small protein removalGO:0070646920.012
sleepGO:003043120.012
startle responseGO:000196430.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of protein complex assemblyGO:00432541470.012
regulation of dna metabolic processGO:00510521530.011
cellular response to external stimulusGO:00714961110.011
cellular ion homeostasisGO:00068731680.011
post embryonic organ developmentGO:004856910.011
blood vessel developmentGO:00015681720.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
mitochondrion organizationGO:00070051560.011
establishment of protein localization to membraneGO:00901501210.011
regulation of meiotic cell cycleGO:005144540.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
myoblast fusionGO:000752010.011
vasculature developmentGO:00019441810.011
response to fungusGO:000962040.011
regulation of protein serine threonine kinase activityGO:00719001790.011
regulation of neurotransmitter secretionGO:004692830.011
positive regulation of cell activationGO:0050867810.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
cellular chemical homeostasisGO:00550821800.011
tissue migrationGO:00901301190.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
metal ion homeostasisGO:00550651690.011
ameboidal type cell migrationGO:00016671350.011
calcium ion transportGO:00068161470.011
positive regulation of cell cycleGO:00457871400.011
nerve developmentGO:002167540.011
endocytosisGO:00068971590.011
positive regulation of lymphocyte activationGO:0051251730.011
photoreceptor cell differentiationGO:004653020.011
response to nitrogen compoundGO:19016981840.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
membrane hyperpolarizationGO:006008110.011
positive regulation of protein kinase activityGO:00458601900.011
cell substrate adhesionGO:00315891320.011
positive regulation of peptidase activityGO:0010952880.011
positive regulation of innate immune responseGO:0045089790.011
alcohol metabolic processGO:00060661140.011
sex determinationGO:000753030.011
sensory perception of smellGO:000760820.011
defense response to virusGO:0051607710.011
immune response activating cell surface receptor signaling pathwayGO:0002429450.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
regulation of cellular protein catabolic processGO:1903362960.011
organic anion transportGO:00157111030.011
regulation of growthGO:00400081650.011
sensory perception of painGO:001923340.011
regulation of lymphocyte activationGO:00512491030.011
negative regulation of cell cycle processGO:00109481210.011
regulation of vesicle mediated transportGO:00606271300.011
establishment of tissue polarityGO:000716430.011
neuron projection regenerationGO:003110210.011
pattern recognition receptor signaling pathwayGO:0002221480.011
epithelium migrationGO:00901321190.011
regulation of circadian sleep wake cycle sleepGO:004518720.011
atp catabolic processGO:00062001570.011
sequestering of calcium ionGO:0051208170.011
regulation of wnt signaling pathwayGO:00301111230.011
negative regulation of transferase activityGO:00513481240.011
central nervous system developmentGO:00074171230.011
neurogenesisGO:00220081690.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
neural tube formationGO:000184130.011
establishment of planar polarityGO:000173630.011
rab protein signal transductionGO:003248240.011
cerebellum developmentGO:002154920.011
fatty acid metabolic processGO:00066311150.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
protein importGO:00170381300.010
somatic muscle developmentGO:000752510.010
tube closureGO:006060630.010
autophagyGO:0006914880.010
positive regulation of nf kappab transcription factor activityGO:0051092810.010
glycerolipid metabolic processGO:00464861070.010
protein o linked glycosylation via serineGO:001824230.010
defense response to fungusGO:005083240.010
regulation of actin filament based processGO:00329701410.010
negative regulation of organelle organizationGO:00106391260.010
immune system developmentGO:00025201950.010
regulation of transmembrane transportGO:00347621390.010
positive regulation of locomotionGO:00400171860.010
innate immune response activating signal transductionGO:0002758480.010
cell projection morphogenesisGO:00488581290.010
cellular metal ion homeostasisGO:00068751460.010
regulation of cell growthGO:00015581350.010
melanin metabolic processGO:000658210.010
forelimb morphogenesisGO:003513640.010

ERAP2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.024
sensory system diseaseDOID:00501552030.023
nervous system diseaseDOID:8634310.023
disease of metabolismDOID:00146672950.022
central nervous system diseaseDOID:3311860.020
inherited metabolic disorderDOID:6552420.019
disease of cellular proliferationDOID:145661740.019
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
immune system diseaseDOID:29141550.018
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
connective tissue diseaseDOID:651090.016
bone diseaseDOID:0080001880.016
muscle tissue diseaseDOID:661130.015
muscular diseaseDOID:00800001140.015
cardiovascular system diseaseDOID:12871060.015
retinal diseaseDOID:56791180.014
neurodegenerative diseaseDOID:12891020.012
myopathyDOID:4231040.012
disease of mental healthDOID:150700.011
hematopoietic system diseaseDOID:741000.010
brain diseaseDOID:936730.010