Homo sapiens

22 known processes

DEFB1

defensin, beta 1

(Aliases: DEFB101,DEFB-1,HBD1,BD1,MGC51822)

DEFB1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid metabolic processGO:00066293810.086
response to oxygen containing compoundGO:19017003690.085
system processGO:00030083490.068
cellular amino acid metabolic processGO:00065201160.064
negative regulation of cell deathGO:00605483450.063
cellular lipid metabolic processGO:00442553030.063
chemical homeostasisGO:00488783060.062
anion transportGO:00068201610.061
cellular ketone metabolic processGO:0042180800.061
ion transmembrane transportGO:00342203380.060
cellular response to oxygen containing compoundGO:19017012760.055
response to organic cyclic compoundGO:00140702040.055
transmembrane transportGO:00550853990.055
cation homeostasisGO:00550801890.054
positive regulation of transportGO:00510503360.054
regulation of cellular component movementGO:00512703340.053
post embryonic developmentGO:000979120.053
ion homeostasisGO:00508012300.053
vitamin e metabolic processGO:004236010.051
actin filament based processGO:00300292240.050
cellular response to endogenous stimulusGO:00714953360.050
organic anion transportGO:00157111030.049
response to lipidGO:00339932060.047
negative regulation of apoptotic processGO:00430663160.046
mapk cascadeGO:00001652880.044
ras protein signal transductionGO:0007265730.044
regulation of hormone levelsGO:00108171250.044
regulation of cellular amino acid metabolic processGO:000652160.043
small gtpase mediated signal transductionGO:0007264780.043
response to other organismGO:00517072610.043
cardiac muscle cell contractionGO:008600340.043
cytoplasmic transportGO:00164823790.043
multicellular organismal agingGO:001025930.043
regulation of mapk cascadeGO:00434082620.043
organic hydroxy compound metabolic processGO:19016151470.043
enzyme linked receptor protein signaling pathwayGO:00071673030.042
determination of adult lifespanGO:000834020.041
positive regulation of phosphorylationGO:00423273940.041
inorganic ion transmembrane transportGO:00986602310.041
fatty acid metabolic processGO:00066311150.041
defense responseGO:00069523150.041
locomotory behaviorGO:000762610.041
vesicle mediated transportGO:00161923710.040
protein maturationGO:00516042330.040
protein processingGO:00164852260.039
positive regulation of cellular amine metabolic processGO:003324070.039
response to biotic stimulusGO:00096072760.039
signal transduction by phosphorylationGO:00230142970.039
amine metabolic processGO:0009308440.039
secretionGO:00469032540.038
oxidation reduction processGO:00551143960.038
cellular amine metabolic processGO:0044106410.038
negative regulation of programmed cell deathGO:00430693210.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
regulation of cellular amine metabolic processGO:0033238110.037
regulation of locomotionGO:00400123290.037
cation transmembrane transportGO:00986552380.037
positive regulation of cell deathGO:00109422630.036
cation transportGO:00068123310.036
positive regulation of cellular component organizationGO:00511303760.036
response to abiotic stimulusGO:00096283360.036
positive regulation of mapk cascadeGO:00434101900.036
alcohol metabolic processGO:00060661140.035
monocarboxylic acid metabolic processGO:00327871850.035
metal ion transportGO:00300012720.035
positive regulation of immune system processGO:00026842830.035
positive regulation of protein phosphorylationGO:00019343130.035
nitrogen compound transportGO:00717051910.034
response to hormoneGO:00097251750.034
regulation of transferase activityGO:00513383550.034
positive regulation of apoptotic processGO:00430652460.034
matingGO:000761810.034
phylloquinone metabolic processGO:004237420.034
small molecule biosynthetic processGO:00442831570.034
single organism cellular localizationGO:19025803320.034
regenerationGO:003109940.034
positive regulation of hydrolase activityGO:00513453310.033
regulation of cell motilityGO:20001452990.033
fatty acid omega oxidationGO:001043020.033
cell adhesionGO:00071553250.033
response to cytokineGO:00340972320.033
positive regulation of programmed cell deathGO:00430682490.033
negative regulation of icosanoid secretionGO:003230420.032
epithelium developmentGO:00604292270.032
endomembrane system organizationGO:00102561960.032
secretion by cellGO:00329402260.031
lipid biosynthetic processGO:00086101770.031
membrane organizationGO:00610242920.031
negative regulation of multicellular organismal processGO:00512413170.031
regulation of protein kinase activityGO:00458592890.031
regulation of cell differentiationGO:00455953930.031
purine nucleotide catabolic processGO:00061954050.031
negative regulation of catalytic activityGO:00430863350.031
regulation of kinase activityGO:00435493140.031
carbohydrate derivative biosynthetic processGO:19011372070.031
purine ribonucleoside metabolic processGO:00461284370.030
inorganic cation transmembrane transportGO:00986621940.030
positive regulation of kinase activityGO:00336742040.030
single organism membrane organizationGO:00448022680.030
biological adhesionGO:00226103310.030
ribonucleoside catabolic processGO:00424544060.030
regulation of proteolysisGO:00301622930.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
response to woundingGO:00096111680.029
negative regulation of cellular protein metabolic processGO:00322693530.029
response to external biotic stimulusGO:00432072610.029
intracellular protein transportGO:00068862700.029
organophosphate catabolic processGO:00464344300.029
calcium ion homeostasisGO:00550741220.028
immune responseGO:00069553070.028
negative regulation of protein metabolic processGO:00512483910.028
purine ribonucleoside catabolic processGO:00461303980.028
regulation of cellular response to stressGO:00801352440.028
nucleoside catabolic processGO:00091644080.028
regulation of anatomical structure morphogenesisGO:00226032860.028
cellular chemical homeostasisGO:00550821800.028
steroid metabolic processGO:0008202940.028
lipid catabolic processGO:0016042840.027
female gamete generationGO:000729220.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
epithelial cell differentiationGO:00308551410.027
keratinizationGO:003142420.027
regulation of cell migrationGO:00303342890.027
cytokine productionGO:00018162470.026
purine containing compound catabolic processGO:00725234110.026
protein oligomerizationGO:00512591730.026
apoptotic signaling pathwayGO:00971902680.026
regulation of apoptotic signaling pathwayGO:20012331750.026
organonitrogen compound biosynthetic processGO:19015662000.026
nucleotide catabolic processGO:00091664080.026
regulation of response to external stimulusGO:00321012220.025
leukotriene b4 metabolic processGO:003610220.025
regulation of secretionGO:00510461940.025
reactive oxygen species biosynthetic processGO:190340940.025
g protein coupled receptor signaling pathwayGO:00071862070.025
oogenesisGO:004847720.025
behavioral response to ethanolGO:004814920.025
menaquinone metabolic processGO:000923330.025
cellular response to nitrogen compoundGO:19016991440.024
rho protein signal transductionGO:0007266260.024
positive regulation of catabolic processGO:00098963100.024
carbohydrate metabolic processGO:00059752070.024
regulation of secretion by cellGO:19035301770.024
rhythmic behaviorGO:000762220.024
nucleoside triphosphate catabolic processGO:00091433940.024
regulation of cellular ketone metabolic processGO:0010565500.024
cellular macromolecular complex assemblyGO:00346223240.024
purine nucleoside catabolic processGO:00061523980.024
interspecies interaction between organismsGO:00444191560.024
viral life cycleGO:00190581320.024
cellular homeostasisGO:00197251960.024
regulation of nucleotide metabolic processGO:00061402690.024
response to nitrogen compoundGO:19016981840.024
innate immune responseGO:00450871780.024
epidermis morphogenesisGO:004873030.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
response to organonitrogen compoundGO:00102431560.024
protein catabolic processGO:00301633250.023
cellular macromolecule catabolic processGO:00442653800.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
regulation of immune responseGO:00507762010.023
actin mediated cell contractionGO:0070252120.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
reactive oxygen species metabolic processGO:0072593750.023
cellular metal ion homeostasisGO:00068751460.023
glycosyl compound catabolic processGO:19016584130.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
regulation of protein maturationGO:19033171500.023
memoryGO:000761330.023
regulation of cell adhesionGO:00301551660.023
circadian behaviorGO:004851220.023
cellular response to organonitrogen compoundGO:00714171240.023
metal ion homeostasisGO:00550651690.023
sensory perception of painGO:001923340.022
epoxygenase p450 pathwayGO:001937330.022
cellular component morphogenesisGO:00329893140.022
cellular cation homeostasisGO:00300031630.022
reactive nitrogen species metabolic processGO:200105730.022
organic acid biosynthetic processGO:0016053970.022
carboxylic acid biosynthetic processGO:0046394970.022
behaviorGO:00076101120.022
purine ribonucleotide catabolic processGO:00091544040.022
response to bacteriumGO:00096171440.022
regulation of reactive oxygen species metabolic processGO:2000377410.022
regulation of protein localizationGO:00328802960.022
cellular ion homeostasisGO:00068731680.022
carboxylic acid transportGO:0046942630.022
regulation of multi organism processGO:00439001570.022
nervous system developmentGO:00073992930.021
negative regulation of hydrolase activityGO:00513461820.021
positive regulation of transferase activityGO:00513472270.021
regulation of jnk cascadeGO:0046328730.021
ribonucleotide catabolic processGO:00092614050.021
protein localization to organelleGO:00333652800.021
nucleoside phosphate catabolic processGO:19012924120.021
positive regulation of nucleotide metabolic processGO:00459812300.021
i kappab kinase nf kappab signalingGO:00072491660.021
defense response to other organismGO:00985421290.020
neuromuscular junction developmentGO:000752830.020
peripheral nervous system developmentGO:000742220.020
sodium ion transmembrane transportGO:0035725590.020
vitamin metabolic processGO:0006766260.020
response to inorganic substanceGO:00100351270.020
gtp metabolic processGO:00460392390.020
regulation of purine nucleotide metabolic processGO:19005422640.020
actin cytoskeleton organizationGO:00300362070.020
positive regulation of cellular catabolic processGO:00313312840.020
viral processGO:00160321460.020
multi organism cellular processGO:00447641560.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
regulation of peptidase activityGO:00525471800.020
regulation of establishment of protein localizationGO:00702012420.020
regulation of protein processingGO:00706131500.020
cell activationGO:00017752130.020
regulation of reactive oxygen species biosynthetic processGO:190342630.020
regulation of protein transportGO:00512232130.020
maintenance of locationGO:00512351120.020
menaquinone catabolic processGO:004236120.019
positive regulation of protein kinase activityGO:00458601900.019
positive regulation of cell migrationGO:00303351720.019
nucleoside triphosphate metabolic processGO:00091414220.019
retinoic acid biosynthetic processGO:000213820.019
positive regulation of developmental processGO:00510943140.019
guanosine containing compound catabolic processGO:19010692390.019
9 cis retinoic acid metabolic processGO:004290510.019
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.019
fatty acid derivative catabolic processGO:190156920.019
defense response to fungusGO:005083240.019
response to metal ionGO:0010038840.019
organic acid transportGO:0015849650.019
renal water homeostasisGO:000309140.019
establishment of protein localization to membraneGO:00901501210.019
negative regulation of protein processingGO:00109551420.019
single organism carbohydrate metabolic processGO:00447231930.019
multicellular organismal response to stressGO:003355510.019
regulation of cell cycleGO:00517263930.019
positive regulation of immune responseGO:00507781590.019
regulation of endopeptidase activityGO:00525481700.019
unsaturated fatty acid metabolic processGO:0033559370.019
regulation of intracellular transportGO:00323861950.019
spermatid differentiationGO:004851540.019
regulation of protein serine threonine kinase activityGO:00719001790.019
protein homooligomerizationGO:00512601000.019
monovalent inorganic cation transportGO:00156721280.018
lipid localizationGO:00108761060.018
sulfur compound metabolic processGO:00067901010.018
response to fungusGO:000962040.018
mitotic cell cycleGO:00002783260.018
regulation of cellular component biogenesisGO:00440872810.018
copulationGO:000762010.018
regulation of cytoskeleton organizationGO:00514931770.018
regulation of cytokine productionGO:00018172320.018
negative regulation of protein maturationGO:19033181420.018
regulation of nucleotide catabolic processGO:00308112050.018
single organism cell adhesionGO:00986021790.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.018
negative regulation of cell proliferationGO:00082852280.018
positive regulation of reactive oxygen species metabolic processGO:2000379240.018
cellular protein catabolic processGO:00442572610.018
sequestering of metal ionGO:0051238240.018
regulation of actin filament based processGO:00329701410.018
cellular response to cytokine stimulusGO:00713451810.018
regulation of defense responseGO:00313471540.018
regulation of membrane potentialGO:0042391950.018
stress activated protein kinase signaling cascadeGO:0031098940.018
cell substrate adhesionGO:00315891320.018
leukotriene catabolic processGO:003610020.018
segmentationGO:003528240.018
morphogenesis of embryonic epitheliumGO:001633140.018
circulatory system processGO:00030131130.017
amide transportGO:0042886760.017
positive regulation of reactive oxygen species biosynthetic processGO:190342820.017
negative regulation of phosphate metabolic processGO:00459362670.017
cellular protein complex assemblyGO:00436231880.017
negative regulation of phosphorus metabolic processGO:00105632670.017
regulation of viral processGO:00507921030.017
fatty acid derivative metabolic processGO:1901568350.017
positive regulation of cell differentiationGO:00455972110.017
protein targetingGO:00066051870.017
growthGO:00400072020.017
cell projection organizationGO:00300302520.017
spermatid developmentGO:000728640.017
compound eye developmentGO:004874910.017
positive regulation of cell motilityGO:20001471770.017
vitamin k biosynthetic processGO:004237120.017
actin filament based movementGO:0030048170.017
regulation of i kappab kinase nf kappab signalingGO:00431221620.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
mitotic cell cycle processGO:19030472860.017
positive regulation of secretion by cellGO:19035321080.017
neurological system processGO:00508771630.017
negative regulation of locomotionGO:00400131180.017
divalent inorganic cation homeostasisGO:00725071360.017
cell developmentGO:00484683280.017
blood circulationGO:00080151130.017
peptidyl tyrosine phosphorylationGO:00181081700.017
cell morphogenesisGO:00009022960.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
phylloquinone catabolic processGO:004237620.016
jnk cascadeGO:0007254800.016
positive regulation of synaptic transmissionGO:005080640.016
skin developmentGO:0043588760.016
regulation of system processGO:00440571010.016
positive regulation of map kinase activityGO:0043406800.016
cellular divalent inorganic cation homeostasisGO:00725031280.016
positive regulation of organelle organizationGO:00106381950.016
photoreceptor cell differentiationGO:004653020.016
guanosine containing compound metabolic processGO:19010682440.016
cellular response to growth factor stimulusGO:00713631970.016
epithelium migrationGO:00901321190.016
ketone catabolic processGO:004218230.016
negative regulation of transportGO:00510511760.016
protein localization to membraneGO:00726571600.016
sensory perceptionGO:00076001030.016
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.016
positive regulation of locomotionGO:00400171860.016
regulation of ion transportGO:00432691890.016
embryonic epithelial tube formationGO:000183840.016
primary alcohol metabolic processGO:0034308170.016
cardiovascular system developmentGO:00723582620.016
tissue migrationGO:00901301190.016
small molecule catabolic processGO:0044282920.016
positive regulation of cell proliferationGO:00082843010.016
positive regulation of cellular component movementGO:00512721810.016
oocyte developmentGO:004859910.016
regulation of body fluid levelsGO:0050878990.016
epithelial cell migrationGO:00106311190.016
organophosphate biosynthetic processGO:00904071630.016
leukotriene b4 catabolic processGO:003610120.016
follicle stimulating hormone secretionGO:004688430.016
sensory perception of smellGO:000760820.016
regulation of cell cycle processGO:00105642660.016
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.016
glycoprotein metabolic processGO:00091001100.016
negative regulation of proteolysisGO:00458611320.016
cellular response to organic cyclic compoundGO:00714071270.016
anterior posterior axis specificationGO:000994820.015
salivary gland morphogenesisGO:000743540.015
cofactor metabolic processGO:0051186870.015
response to drugGO:0042493810.015
positive regulation of secretionGO:00510471160.015
cell cell signalingGO:00072671550.015
tissue regenerationGO:004224630.015
regulation of stress activated protein kinase signaling cascadeGO:0070302850.015
regulation of stress activated mapk cascadeGO:0032872840.015
cellular response to hormone stimulusGO:00328701250.015
keratinocyte differentiationGO:0030216360.015
striated muscle contractionGO:0006941520.015
negative regulation of developmental processGO:00510932470.015
activation of immune responseGO:00022531140.015
muscle contractionGO:0006936730.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
chemotaxisGO:00069351570.015
sequestering of calcium ionGO:0051208170.015
positive regulation of cellular component biogenesisGO:00440891580.015
regulation of growthGO:00400081650.015
icosanoid catabolic processGO:190152320.015
organelle assemblyGO:00709251760.015
positive regulation of protein transportGO:00512221350.015
regulation of nucleoside metabolic processGO:00091182090.015
response to growth factorGO:00708482050.015
peptide transportGO:0015833740.015
protein secretionGO:0009306980.015
cellular calcium ion homeostasisGO:00068741170.015
regulation of ras protein signal transductionGO:00465781550.015
cardiac muscle contractionGO:0060048340.015
glial cell migrationGO:000834740.015
positive regulation of intracellular transportGO:00323881040.015
dephosphorylationGO:00163112090.015
positive regulation of nucleoside metabolic processGO:00459791860.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
monocarboxylic acid biosynthetic processGO:0072330670.015
regulation of purine nucleotide catabolic processGO:00331212050.015
positive regulation of gtp catabolic processGO:00331261660.015
negative regulation of cellular amine metabolic processGO:003323930.015
regulation of synaptic plasticityGO:004816730.015
regulation of gtpase activityGO:00430871800.015
regulation of ion transmembrane transportGO:00347651320.015
response to axon injuryGO:004867810.015
protein ubiquitinationGO:00165673140.015
regulation of peptide transportGO:0090087620.014
developmental programmed cell deathGO:001062330.014
gtp catabolic processGO:00061842370.014
quinone catabolic processGO:190166220.014
positive regulation of vasoconstrictionGO:004590730.014
leukocyte migrationGO:00509001070.014
regulation of cytoplasmic transportGO:19036491490.014
immune effector processGO:00022521590.014
protein localization to plasma membraneGO:0072659930.014
wound healingGO:00420601150.014
vitamin k catabolic processGO:004237720.014
response to salt stressGO:000965130.014
posttranscriptional regulation of gene expressionGO:00106082130.014
positive regulation of stress activated mapk cascadeGO:0032874600.014
icosanoid metabolic processGO:0006690350.014
positive regulation of cytosolic calcium ion concentrationGO:0007204820.014
oocyte differentiationGO:000999420.014
regulation of feeding behaviorGO:006025930.014
response to virusGO:00096151260.014
positive regulation of gtpase activityGO:00435471660.014
hemostasisGO:0007599760.014
blastoderm segmentationGO:000735020.014
multicellular organismal signalingGO:0035637340.014
regulation of cell developmentGO:00602841610.014
negative regulation of intracellular signal transductionGO:19025321830.014
positive regulation of ion transportGO:0043270870.014
regulation of map kinase activityGO:00434051080.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
isoprenoid metabolic processGO:0006720390.014
regulation of protein catabolic processGO:00421761550.014
positive regulation of nucleotide catabolic processGO:00308131850.014
cdc42 protein signal transductionGO:003248840.014
pressure natriuresisGO:000309520.014
serotonin uptakeGO:005161020.014
epithelial cell proliferationGO:00506731280.014
muscle system processGO:0003012810.014
protein modification by small protein conjugationGO:00324463420.014
epidermis developmentGO:0008544590.014
cell type specific apoptotic processGO:00972851250.014
hindbrain developmentGO:003090230.014
cellular response to dna damage stimulusGO:00069743790.014
nucleocytoplasmic transportGO:00069131760.014
hormone transportGO:0009914680.014
response to activityGO:001482300.014
regulation of vesicle mediated transportGO:00606271300.014
midgut developmentGO:000749410.014
hormone secretionGO:0046879650.013
circulatory system developmentGO:00723592620.013
negative regulation of cellular component movementGO:00512711060.013
response to steroid hormoneGO:0048545800.013
ameboidal type cell migrationGO:00016671350.013
nuclear transportGO:00511691790.013
cell divisionGO:00513011680.013
inseminationGO:000732010.013
negative regulation of cell motilityGO:20001461040.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
blood vessel morphogenesisGO:00485141620.013
anterior posterior axis specification embryoGO:000859520.013
negative regulation of interferon gamma secretionGO:190271410.013
cellular response to lipidGO:00713961270.013
response to molecule of bacterial originGO:0002237820.013
renal system process involved in regulation of blood volumeGO:000197740.013
nerve developmentGO:002167540.013
cytosolic calcium ion homeostasisGO:0051480890.013
cellular response to glucocorticoid stimulusGO:007138540.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
protein autophosphorylationGO:00467771230.013
organ morphogenesisGO:00098871470.013
adult locomotory behaviorGO:000834410.013
positive regulation of proteolysisGO:00458621420.013
organ formationGO:004864530.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
coenzyme metabolic processGO:0006732650.013
regulation of ras gtpase activityGO:00323181280.013
cell matrix adhesionGO:0007160850.013
positive regulation of cytoplasmic transportGO:1903651820.013
positive regulation of jnk cascadeGO:0046330520.013
negative regulation of endopeptidase activityGO:0010951840.013
cell fate determinationGO:000170930.013
long chain fatty acid catabolic processGO:004275830.013
tripartite regional subdivisionGO:000735120.013
tissue morphogenesisGO:0048729960.013
regulation of neural precursor cell proliferationGO:200017740.013
protein kinase b signalingGO:0043491690.013
regulation of transmembrane transportGO:00347621390.013
anion transmembrane transportGO:0098656760.013
hair follicle morphogenesisGO:003106920.013
negative regulation of cellular component organizationGO:00511292350.013
calcium ion transportGO:00068161470.013
establishment of protein localization to organelleGO:00725941720.012
regulation of gtp catabolic processGO:00331241800.012
microtubule based processGO:00070172100.012

DEFB1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
kidney diseaseDOID:557360.042
urinary system diseaseDOID:18400.042
renal tubular transport diseaseDOID:447110.042
sensory system diseaseDOID:00501552030.031
nervous system diseaseDOID:8634310.031
musculoskeletal system diseaseDOID:172230.029
disease of metabolismDOID:00146672950.027
disease of cellular proliferationDOID:145661740.023
cancerDOID:1621670.023
inherited metabolic disorderDOID:6552420.023
organ system cancerDOID:00506861640.021
immune system diseaseDOID:29141550.019
eye and adnexa diseaseDOID:14921500.019
connective tissue diseaseDOID:651090.018
bone diseaseDOID:0080001880.018
eye diseaseDOID:56141490.016
retinal diseaseDOID:56791180.016
central nervous system diseaseDOID:3311860.016
auditory system diseaseDOID:2742530.015
cardiovascular system diseaseDOID:12871060.014
hematopoietic system diseaseDOID:741000.013