Homo sapiens

0 known processes

DIABLO

diablo, IAP-binding mitochondrial protein

(Aliases: SMAC,FLJ10537,FLJ25049,SMAC3,DIABLO-S)

DIABLO biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of peptidase activityGO:00525471800.514
cellular macromolecule catabolic processGO:00442653800.403
positive regulation of apoptotic signaling pathwayGO:2001235700.384
protein modification by small protein conjugationGO:00324463420.277
regulation of i kappab kinase nf kappab signalingGO:00431221620.275
negative regulation of cell deathGO:00605483450.254
post embryonic developmentGO:000979120.198
regulation of cysteine type endopeptidase activityGO:20001161270.196
adult locomotory behaviorGO:000834410.190
positive regulation of apoptotic processGO:00430652460.183
positive regulation of programmed cell deathGO:00430682490.183
cellular protein catabolic processGO:00442572610.178
regulation of endopeptidase activityGO:00525481700.168
extrinsic apoptotic signaling pathwayGO:00971911190.163
negative regulation of apoptotic processGO:00430663160.155
regulation of cell differentiationGO:00455953930.152
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.136
proteolysis involved in cellular protein catabolic processGO:00516032440.136
negative regulation of cellular protein metabolic processGO:00322693530.126
mitochondrion organizationGO:00070051560.126
cellular response to dna damage stimulusGO:00069743790.124
cellular response to muramyl dipeptideGO:007122530.119
positive regulation of developmental processGO:00510943140.118
cellular response to external stimulusGO:00714961110.116
locomotory behaviorGO:000762610.115
regulation of proteolysisGO:00301622930.111
i kappab kinase nf kappab signalingGO:00072491660.111
protein processingGO:00164852260.106
regulation of cell cycleGO:00517263930.099
negative regulation of programmed cell deathGO:00430693210.091
modification dependent protein catabolic processGO:00199412090.091
protein catabolic processGO:00301633250.090
positive regulation of kinase activityGO:00336742040.090
response to cytokineGO:00340972320.088
cellular amine metabolic processGO:0044106410.087
regulation of protein kinase activityGO:00458592890.087
protein ubiquitinationGO:00165673140.085
regulation of apoptotic signaling pathwayGO:20012331750.080
positive regulation of cell differentiationGO:00455972110.079
regulation of macrophage differentiationGO:004564990.079
lipid metabolic processGO:00066293810.076
negative regulation of protein metabolic processGO:00512483910.075
protein maturationGO:00516042330.075
regulation of kinase activityGO:00435493140.074
positive regulation of macrophage differentiationGO:004565170.070
nitrogen compound transportGO:00717051910.068
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.068
negative regulation of cysteine type endopeptidase activityGO:2000117480.068
mitotic cell cycle phase transitionGO:00447721620.066
positive regulation of myeloid cell differentiationGO:0045639390.066
regulation of cellular amine metabolic processGO:0033238110.065
negative regulation of peptidase activityGO:0010466910.064
positive regulation of hydrolase activityGO:00513453310.064
positive regulation of myeloid leukocyte differentiationGO:0002763240.062
cellular response to cytokine stimulusGO:00713451810.062
negative regulation of apoptotic signaling pathwayGO:2001234970.062
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.062
positive regulation of cysteine type endopeptidase activityGO:2001056790.062
myeloid cell differentiationGO:00300991170.061
positive regulation of proteolysisGO:00458621420.059
response to abiotic stimulusGO:00096283360.059
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.057
regulation of leukocyte activationGO:00026941150.057
g1 s transition of mitotic cell cycleGO:0000082780.056
cellular response to oxygen containing compoundGO:19017012760.056
positive regulation of cell cycle processGO:00900681060.056
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.055
regulation of canonical wnt signaling pathwayGO:0060828880.055
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.054
ubiquitin dependent protein catabolic processGO:00065112060.053
apoptotic signaling pathwayGO:00971902680.053
negative regulation of catalytic activityGO:00430863350.053
response to oxygen containing compoundGO:19017003690.053
intrinsic apoptotic signaling pathwayGO:00971931270.052
regulation of wnt signaling pathwayGO:00301111230.051
negative regulation of endopeptidase activityGO:0010951840.051
amine metabolic processGO:0009308440.050
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.050
trail activated apoptotic signaling pathwayGO:003646240.050
wnt signaling pathwayGO:00160551560.049
substantia nigra developmentGO:0021762450.046
regulation of leukocyte differentiationGO:1902105610.046
positive regulation of peptidase activityGO:0010952880.045
regulation of cellular amino acid metabolic processGO:000652160.045
positive regulation of cellular amino acid metabolic processGO:004576430.044
response to biotic stimulusGO:00096072760.044
cellular amino acid metabolic processGO:00065201160.044
cellular lipid metabolic processGO:00442553030.043
regulation of protein maturationGO:19033171500.042
dna damage response signal transduction by p53 class mediatorGO:0030330440.041
positive regulation of cell deathGO:00109422630.041
embryo developmentGO:00097901230.041
positive regulation of immune system processGO:00026842830.041
regulation of cell cycle processGO:00105642660.041
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.041
positive regulation of cellular amine metabolic processGO:003324070.040
regulation of myeloid cell differentiationGO:0045637810.040
protein polyubiquitinationGO:00002091100.040
cardiac ventricle formationGO:000321120.039
negative regulation of hydrolase activityGO:00513461820.038
regulation of response to dna damage stimulusGO:2001020940.036
cellular response to endogenous stimulusGO:00714953360.036
cellular response to abiotic stimulusGO:00712141170.036
cellular response to lipidGO:00713961270.036
neuromuscular junction developmentGO:000752830.035
regulation of mitotic cell cycle phase transitionGO:19019901180.035
female gamete generationGO:000729220.034
signal transduction in absence of ligandGO:0038034220.033
nucleobase containing compound transportGO:0015931510.033
regulation of transmembrane transporter activityGO:0022898740.032
regulation of transferase activityGO:00513383550.032
canonical wnt signaling pathwayGO:00600701160.031
transmembrane transportGO:00550853990.031
regulation of neuron deathGO:1901214560.031
regulation of cellular response to stressGO:00801352440.031
immune effector processGO:00022521590.031
neuron deathGO:0070997650.031
negative regulation of proteolysisGO:00458611320.031
determination of adult lifespanGO:000834020.030
positive regulation of protein ubiquitinationGO:0031398530.030
proteasomal protein catabolic processGO:00104981760.029
cell type specific apoptotic processGO:00972851250.029
oogenesisGO:004847720.029
startle responseGO:000196430.028
cardiac right ventricle morphogenesisGO:000321530.028
vesicle mediated transportGO:00161923710.028
regulation of t cell proliferationGO:0042129420.027
system processGO:00030083490.026
regulation of protein processingGO:00706131500.026
cell cycle arrestGO:0007050710.026
zymogen activationGO:0031638700.026
ion transmembrane transportGO:00342203380.026
aortic valve developmentGO:000317630.026
positive regulation of neuron deathGO:1901216140.026
growthGO:00400072020.026
cardiac right ventricle formationGO:000321910.026
epithelial cell differentiationGO:00308551410.025
secretionGO:00469032540.025
cell cycle phase transitionGO:00447701730.025
regulation of cell cycle g1 s phase transitionGO:1902806420.025
dna damage checkpointGO:0000077680.025
photoreceptor cell differentiationGO:004653020.025
regulation of mitotic cell cycleGO:00073461890.024
membrane organizationGO:00610242920.024
regulation of necroptotic processGO:006054470.024
multicellular organismal agingGO:001025930.024
response to hormoneGO:00097251750.024
regulation of cytoskeleton organizationGO:00514931770.024
regulation of cell cycle phase transitionGO:19019871260.024
membrane lipid metabolic processGO:0006643530.024
negative regulation of cell cycleGO:00457861930.024
response to decreased oxygen levelsGO:0036293960.024
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.024
innate immune responseGO:00450871780.023
limbic system developmentGO:002176130.023
release of cytochrome c from mitochondriaGO:0001836350.023
negative regulation of protein processingGO:00109551420.023
regulation of protein ubiquitinationGO:0031396950.023
programmed necrotic cell deathGO:0097300180.023
negative regulation of intracellular signal transductionGO:19025321830.023
multicellular organismal reproductive processGO:0048609400.023
defense responseGO:00069523150.023
negative regulation of cellular component organizationGO:00511292350.023
cytokine mediated signaling pathwayGO:00192211090.022
positive regulation of phosphorylationGO:00423273940.022
negative regulation of cell cycle processGO:00109481210.022
activation of cysteine type endopeptidase activityGO:0097202570.022
negative regulation of developmental processGO:00510932470.022
regulation of cell divisionGO:00513021160.022
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.022
regulation of reactive oxygen species metabolic processGO:2000377410.022
peptidyl serine autophosphorylationGO:003628920.022
negative regulation of cell proliferationGO:00082852280.022
negative regulation of cell cycle phase transitionGO:1901988890.022
lymphocyte activationGO:00466491330.021
signal transduction involved in dna integrity checkpointGO:0072401150.021
negative regulation of protein maturationGO:19033181420.021
cellular response to uvGO:0034644320.021
cell activationGO:00017752130.021
regulation of protein modification by small protein conjugation or removalGO:19033201070.021
central nervous system developmentGO:00074171230.021
regulation of growthGO:00400081650.020
regulation of t cell activationGO:0050863770.020
response to woundingGO:00096111680.020
forebrain neuron differentiationGO:002187930.020
leukocyte differentiationGO:0002521980.020
negative regulation of protein modification processGO:00314002000.020
positive regulation of protein polyubiquitinationGO:190291630.020
apoptotic mitochondrial changesGO:0008637570.020
regulation of cell cycle arrestGO:0071156360.020
regulation of hormone levelsGO:00108171250.020
negative regulation of transportGO:00510511760.020
positive regulation of immune responseGO:00507781590.020
mitotic cell cycleGO:00002783260.019
wound healingGO:00420601150.019
positive regulation of transferase activityGO:00513472270.019
regulation of lymphocyte apoptotic processGO:0070228150.019
immune system developmentGO:00025201950.019
cardiac chamber formationGO:000320720.019
regulation of cellular ketone metabolic processGO:0010565500.019
regenerationGO:003109940.019
tissue regenerationGO:004224630.019
myeloid leukocyte differentiationGO:0002573600.019
cellular ketone metabolic processGO:0042180800.019
mitotic cell cycle processGO:19030472860.019
macrophage differentiationGO:0030225110.019
cell adhesionGO:00071553250.018
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043140.018
stress activated protein kinase signaling cascadeGO:0031098940.018
cell projection assemblyGO:00300311260.018
receptor mediated endocytosisGO:0006898840.018
cellular response to acid chemicalGO:0071229440.018
positive regulation of gtp catabolic processGO:00331261660.018
negative regulation of phosphorus metabolic processGO:00105632670.018
positive regulation of protein phosphorylationGO:00019343130.018
cell projection organizationGO:00300302520.018
small gtpase mediated signal transductionGO:0007264780.018
response to oxygen levelsGO:00704821000.018
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.018
sensory perceptionGO:00076001030.018
positive regulation of cellular component organizationGO:00511303760.018
leukocyte activationGO:00453211640.017
oocyte developmentGO:004859910.017
regulation of cell activationGO:00508651250.017
gtp catabolic processGO:00061842370.017
reproductive processGO:00224141060.017
regulation of meiotic cell cycleGO:005144540.017
regulation of protein linear polyubiquitinationGO:190252820.017
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
protein localization to organelleGO:00333652800.017
negative regulation of multicellular organismal processGO:00512413170.017
regulation of cell projection organizationGO:00313441070.017
mitotic g1 s transition checkpointGO:0044819170.017
regulation of cellular component movementGO:00512703340.017
cell cycle g1 s phase transitionGO:0044843800.017
cellular response to organic cyclic compoundGO:00714071270.017
signal transduction involved in cell cycle checkpointGO:0072395160.017
inner ear morphogenesisGO:004247240.016
response to tumor necrosis factorGO:0034612760.016
single organism membrane fusionGO:0044801370.016
biological adhesionGO:00226103310.016
dephosphorylationGO:00163112090.016
regulation of protein serine threonine kinase activityGO:00719001790.016
positive regulation of cell motilityGO:20001471770.016
developmental programmed cell deathGO:001062330.016
cell divisionGO:00513011680.016
positive regulation of nucleotide catabolic processGO:00308131850.016
regulation of actin filament based processGO:00329701410.016
regulation of cell motilityGO:20001452990.016
response to mechanical stimulusGO:0009612510.016
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.016
regulation of myeloid leukocyte differentiationGO:0002761390.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
endocytosisGO:00068971590.015
cation homeostasisGO:00550801890.015
rho protein signal transductionGO:0007266260.015
regulation of microtubule cytoskeleton organizationGO:0070507610.015
lymphocyte proliferationGO:0046651700.015
positive regulation of cellular catabolic processGO:00313312840.015
chemical homeostasisGO:00488783060.015
secretion by cellGO:00329402260.015
regulation of jnk cascadeGO:0046328730.015
regulation of cell adhesionGO:00301551660.015
response to retinoic acidGO:0032526330.015
regulation of cell morphogenesisGO:00226041530.015
response to nitrogen compoundGO:19016981840.015
regulation of anion transportGO:0044070250.015
regulation of nucleotide catabolic processGO:00308112050.015
hindbrain developmentGO:003090230.015
positive regulation of leukocyte differentiationGO:1902107370.014
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.014
embryonic hindlimb morphogenesisGO:003511620.014
autophagyGO:0006914880.014
small molecule biosynthetic processGO:00442831570.014
neuron developmentGO:00486661130.014
cell growthGO:00160491600.014
actin filament based processGO:00300292240.014
regulation of neuron apoptotic processGO:0043523350.014
brain developmentGO:0007420970.014
signal transduction in response to dna damageGO:0042770570.014
response to radiationGO:00093141510.014
cellular response to retinoic acidGO:0071300190.014
cellular macromolecular complex assemblyGO:00346223240.014
cellular response to light stimulusGO:0071482340.014
positive regulation of mapk cascadeGO:00434101900.014
reactive oxygen species metabolic processGO:0072593750.014
purine nucleoside catabolic processGO:00061523980.014
posttranscriptional regulation of gene expressionGO:00106082130.014
regulation of g1 s transition of mitotic cell cycleGO:2000045400.014
motor neuron axon guidanceGO:000804520.014
cellular response to radiationGO:0071478650.014
neurological system processGO:00508771630.014
negative regulation of phosphorylationGO:00423261740.014
positive regulation of protein linear polyubiquitinationGO:190253020.014
positive regulation of protein kinase activityGO:00458601900.014
matingGO:000761810.013
t cell activationGO:0042110990.013
regulation of neural precursor cell proliferationGO:200017740.013
regulation of microtubule based processGO:0032886740.013
positive regulation of nf kappab transcription factor activityGO:0051092810.013
mrna metabolic processGO:00160711750.013
negative regulation of protein phosphorylationGO:00019331400.013
neuron apoptotic processGO:0051402390.013
epithelium developmentGO:00604292270.013
regulation of defense responseGO:00313471540.013
cellular response to nitrogen compoundGO:19016991440.013
t cell homeostasisGO:004302930.013
negative regulation of kinase activityGO:00336731060.013
regulation of mononuclear cell proliferationGO:0032944650.013
lymphocyte apoptotic processGO:0070227200.013
mitotic cell cycle checkpointGO:0007093680.013
leukocyte proliferationGO:0070661740.013
response to organonitrogen compoundGO:00102431560.013
anion transportGO:00068201610.013
actin mediated cell contractionGO:0070252120.013
protein polymerizationGO:0051258710.013
cell morphogenesisGO:00009022960.013
peptide hormone secretionGO:0030072500.013
regulation of stress activated protein kinase signaling cascadeGO:0070302850.013
cellular response to dexamethasone stimulusGO:007154910.013
protein k63 linked ubiquitinationGO:0070534310.013
regulation of cellular protein catabolic processGO:1903362960.013
organophosphate catabolic processGO:00464344300.013
regulation of innate immune responseGO:0045088970.013
immune response activating cell surface receptor signaling pathwayGO:0002429450.013
positive regulation of neuron apoptotic processGO:004352580.012
exocytosisGO:0006887710.012
spermatid developmentGO:000728640.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
cell part morphogenesisGO:00329901370.012
amide transportGO:0042886760.012
leukocyte apoptotic processGO:0071887310.012
peripheral nervous system developmentGO:000742220.012
negative regulation of transferase activityGO:00513481240.012
protein homooligomerizationGO:00512601000.012
stress activated mapk cascadeGO:0051403930.012
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.012
response to uvGO:0009411730.012
b cell homeostasisGO:000178210.012
negative regulation of phosphate metabolic processGO:00459362670.012
response to metal ionGO:0010038840.012
cell substrate adhesionGO:00315891320.012
neurogenesisGO:00220081690.012
regulation of peptidyl serine phosphorylationGO:0033135500.012
purine ribonucleoside metabolic processGO:00461284370.012
single organism membrane organizationGO:00448022680.012
actin filament organizationGO:00070151280.012
regulation of lymphocyte proliferationGO:0050670640.012
positive regulation of organelle organizationGO:00106381950.012
macromolecule methylationGO:0043414970.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of mapk cascadeGO:00434082620.012
regulation of endothelial cell differentiationGO:004560140.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
organelle localizationGO:0051640840.011
negative regulation of immune system processGO:00026831360.011
sensory perception of soundGO:0007605370.011
midbrain developmentGO:0030901450.011
hippocampus developmentGO:002176610.011
associative learningGO:000830610.011
positive regulation of cell proliferationGO:00082843010.011
rna processingGO:00063962550.011
immune response regulating cell surface receptor signaling pathwayGO:0002768510.011
necrotic cell deathGO:0070265210.011
negative regulation of myotube differentiationGO:001083240.011
positive regulation of cardiac muscle tissue growthGO:005502320.011
keratinocyte differentiationGO:0030216360.011
hemopoiesisGO:00300971800.011
regulation of transmembrane transportGO:00347621390.011
regulation of lymphocyte activationGO:00512491030.011
negative regulation of mitotic cell cycle phase transitionGO:1901991850.011
cochlea developmentGO:009010210.011
positive regulation of locomotionGO:00400171860.011
guanosine containing compound catabolic processGO:19010692390.011
regulation of immune effector processGO:0002697910.011
head developmentGO:00603221080.011
regulation of nucleotide metabolic processGO:00061402690.011
dna integrity checkpointGO:0031570710.011
response to bacteriumGO:00096171440.011
cytoplasmic transportGO:00164823790.011
positive regulation of cell cycleGO:00457871400.011
neural nucleus developmentGO:0048857470.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
regulation of multi organism processGO:00439001570.011
response to muramyl dipeptideGO:003249540.011
response to hypoxiaGO:0001666960.011
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.010
dna catabolic processGO:0006308490.010
response to acid chemicalGO:0001101660.010
organ formationGO:004864530.010
t cell proliferationGO:0042098450.010
ceramide metabolic processGO:0006672250.010
transmission of nerve impulseGO:0019226110.010
rna splicingGO:00083801310.010
atp synthesis coupled electron transportGO:004277340.010
phospholipid metabolic processGO:0006644990.010
mapk cascadeGO:00001652880.010
cell matrix adhesionGO:0007160850.010
negative regulation of canonical wnt signaling pathwayGO:0090090550.010

DIABLO disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.054
cancerDOID:1621670.054
nervous system diseaseDOID:8634310.038
central nervous system diseaseDOID:3311860.038
organ system cancerDOID:00506861640.023
parkinson s diseaseDOID:14330180.019
synucleinopathyDOID:0050890220.019
neurodegenerative diseaseDOID:12891020.019
eye diseaseDOID:56141490.016
eye and adnexa diseaseDOID:14921500.016
sensory system diseaseDOID:00501552030.016
retinal diseaseDOID:56791180.012
retinal degenerationDOID:8466890.011
retinitis pigmentosaDOID:10584510.011