Homo sapiens

68 known processes

SMPD4

sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)

(Aliases: FLJ20756,FLJ20297,NSMASE3,NSMASE-3,NET13,KIAA1418)

SMPD4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.093
multicellular organismal agingGO:001025930.044
rna processingGO:00063962550.044
cellular amino acid metabolic processGO:00065201160.043
regulation of cellular amine metabolic processGO:0033238110.042
defense responseGO:00069523150.036
cellular ketone metabolic processGO:0042180800.036
regulation of cellular amino acid metabolic processGO:000652160.035
determination of adult lifespanGO:000834020.035
amine metabolic processGO:0009308440.033
oogenesisGO:004847720.033
regulation of cellular ketone metabolic processGO:0010565500.033
cytoplasmic transportGO:00164823790.033
lipid metabolic processGO:00066293810.033
female gamete generationGO:000729220.033
cellular response to dna damage stimulusGO:00069743790.032
chromatin organizationGO:00063253510.031
cellular lipid metabolic processGO:00442553030.031
negative regulation of cellular protein metabolic processGO:00322693530.029
cellular amine metabolic processGO:0044106410.028
modification dependent macromolecule catabolic processGO:00436322120.028
nucleoside triphosphate catabolic processGO:00091433940.028
positive regulation of cellular amine metabolic processGO:003324070.028
cellular macromolecule catabolic processGO:00442653800.027
ribonucleoside catabolic processGO:00424544060.027
glycosyl compound catabolic processGO:19016584130.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
negative regulation of protein metabolic processGO:00512483910.027
regulation of cell cycleGO:00517263930.027
response to other organismGO:00517072610.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
response to external biotic stimulusGO:00432072610.025
positive regulation of catabolic processGO:00098963100.025
organophosphate catabolic processGO:00464344300.025
regulation of cell differentiationGO:00455953930.024
mrna metabolic processGO:00160711750.023
cellular macromolecular complex assemblyGO:00346223240.023
positive regulation of cellular component organizationGO:00511303760.023
mitotic cell cycleGO:00002783260.023
intracellular protein transportGO:00068862700.022
negative regulation of catalytic activityGO:00430863350.022
mitotic cell cycle processGO:19030472860.022
nervous system developmentGO:00073992930.022
chromatin modificationGO:00165682980.022
cell growthGO:00160491600.022
response to oxygen containing compoundGO:19017003690.022
regulation of cell growthGO:00015581350.022
ras protein signal transductionGO:0007265730.022
single organism carbohydrate metabolic processGO:00447231930.021
small gtpase mediated signal transductionGO:0007264780.021
protein localization to organelleGO:00333652800.021
dna repairGO:00062811980.021
apoptotic signaling pathwayGO:00971902680.020
negative regulation of cell deathGO:00605483450.020
purine ribonucleoside metabolic processGO:00461284370.020
nuclear transportGO:00511691790.020
purine containing compound catabolic processGO:00725234110.020
carbohydrate metabolic processGO:00059752070.020
immune responseGO:00069553070.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
locomotory behaviorGO:000762610.020
negative regulation of phosphorus metabolic processGO:00105632670.020
single organism cellular localizationGO:19025803320.020
histone modificationGO:00165702510.019
positive regulation of hydrolase activityGO:00513453310.019
cell projection organizationGO:00300302520.019
nucleoside triphosphate metabolic processGO:00091414220.019
growthGO:00400072020.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
response to abiotic stimulusGO:00096283360.019
membrane organizationGO:00610242920.019
negative regulation of multicellular organismal processGO:00512413170.019
positive regulation of transportGO:00510503360.019
regulation of protein localizationGO:00328802960.019
positive regulation of programmed cell deathGO:00430682490.019
negative regulation of programmed cell deathGO:00430693210.019
single organism membrane organizationGO:00448022680.019
regulation of purine nucleotide metabolic processGO:19005422640.019
cell morphogenesisGO:00009022960.018
regulation of proteolysisGO:00301622930.018
negative regulation of phosphate metabolic processGO:00459362670.018
lipid biosynthetic processGO:00086101770.018
protein catabolic processGO:00301633250.018
nucleocytoplasmic transportGO:00069131760.018
positive regulation of nucleotide metabolic processGO:00459812300.018
negative regulation of protein modification processGO:00314002000.018
actin filament based processGO:00300292240.018
regulation of transferase activityGO:00513383550.017
neuromuscular junction developmentGO:000752830.017
immune effector processGO:00022521590.017
regulation of anatomical structure morphogenesisGO:00226032860.017
negative regulation of cellular component organizationGO:00511292350.017
cellular response to oxygen containing compoundGO:19017012760.017
covalent chromatin modificationGO:00165692540.017
nucleoside catabolic processGO:00091644080.017
positive regulation of cell deathGO:00109422630.017
vesicle mediated transportGO:00161923710.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
maintenance of locationGO:00512351120.017
microtubule based processGO:00070172100.017
regulation of cell cycle processGO:00105642660.017
response to biotic stimulusGO:00096072760.016
posttranscriptional regulation of gene expressionGO:00106082130.016
purine ribonucleotide catabolic processGO:00091544040.016
purine nucleoside catabolic processGO:00061523980.016
purine ribonucleoside catabolic processGO:00461303980.016
negative regulation of apoptotic processGO:00430663160.016
spermatid differentiationGO:004851540.016
cellular component morphogenesisGO:00329893140.016
immune system developmentGO:00025201950.016
cell developmentGO:00484683280.016
transmembrane transportGO:00550853990.016
chemical homeostasisGO:00488783060.015
regulation of mitotic cell cycleGO:00073461890.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
segmentationGO:003528240.015
rho protein signal transductionGO:0007266260.015
cellular protein catabolic processGO:00442572610.015
regulation of growthGO:00400081650.015
negative regulation of intracellular signal transductionGO:19025321830.015
regulation of intracellular transportGO:00323861950.015
ribonucleoside triphosphate metabolic processGO:00091994120.015
defense response to other organismGO:00985421290.015
regulation of cellular component movementGO:00512703340.015
regulation of kinase activityGO:00435493140.015
mitochondrion organizationGO:00070051560.015
nucleoside phosphate catabolic processGO:19012924120.015
regulation of cellular response to stressGO:00801352440.015
dephosphorylationGO:00163112090.015
cation transportGO:00068123310.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of establishment of protein localizationGO:00702012420.014
positive regulation of cell proliferationGO:00082843010.014
nucleotide catabolic processGO:00091664080.014
microtubule cytoskeleton organizationGO:00002261760.014
carbohydrate derivative biosynthetic processGO:19011372070.014
positive regulation of apoptotic processGO:00430652460.014
organonitrogen compound biosynthetic processGO:19015662000.014
establishment of protein localization to organelleGO:00725941720.014
protein maturationGO:00516042330.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
positive regulation of nucleoside metabolic processGO:00459791860.014
protein modification by small protein conjugationGO:00324463420.014
neurogenesisGO:00220081690.014
hemopoiesisGO:00300971800.014
ion transmembrane transportGO:00342203380.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
protein processingGO:00164852260.014
regulation of cytoskeleton organizationGO:00514931770.014
spermatid developmentGO:000728640.014
regulation of cell motilityGO:20001452990.013
negative regulation of cell proliferationGO:00082852280.013
negative regulation of hydrolase activityGO:00513461820.013
negative regulation of developmental processGO:00510932470.013
metal ion transportGO:00300012720.013
positive regulation of cellular catabolic processGO:00313312840.013
protein ubiquitinationGO:00165673140.013
cellular homeostasisGO:00197251960.013
protein targetingGO:00066051870.013
ubiquitin dependent protein catabolic processGO:00065112060.013
ribonucleotide catabolic processGO:00092614050.013
regulation of cellular component biogenesisGO:00440872810.013
regulation of protein kinase activityGO:00458592890.013
positive regulation of organelle organizationGO:00106381950.013
nitrogen compound transportGO:00717051910.013
oocyte differentiationGO:000999420.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
oocyte developmentGO:004859910.013
blastoderm segmentationGO:000735020.013
actin cytoskeleton organizationGO:00300362070.013
positive regulation of immune system processGO:00026842830.013
regulation of protein catabolic processGO:00421761550.013
negative regulation of organelle organizationGO:00106391260.013
organelle assemblyGO:00709251760.013
innate immune responseGO:00450871780.013
regulation of apoptotic signaling pathwayGO:20012331750.013
glycerolipid metabolic processGO:00464861070.012
regulation of nucleotide metabolic processGO:00061402690.012
cell part morphogenesisGO:00329901370.012
regulation of cytoplasmic transportGO:19036491490.012
cellular protein complex assemblyGO:00436231880.012
regulation of protein processingGO:00706131500.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
cell cycle phase transitionGO:00447701730.012
cell projection assemblyGO:00300311260.012
guanosine containing compound metabolic processGO:19010682440.012
protein oligomerizationGO:00512591730.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
regulation of protein transportGO:00512232130.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
regulation of locomotionGO:00400123290.012
mitotic cell cycle phase transitionGO:00447721620.012
negative regulation of cell cycleGO:00457861930.012
purine nucleotide catabolic processGO:00061954050.012
signal transduction by phosphorylationGO:00230142970.012
small molecule biosynthetic processGO:00442831570.012
endosomal transportGO:00161971290.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
proteasomal protein catabolic processGO:00104981760.012
cellular response to endogenous stimulusGO:00714953360.012
oxidation reduction processGO:00551143960.012
endomembrane system organizationGO:00102561960.012
hindbrain developmentGO:003090230.011
regenerationGO:003109940.011
memoryGO:000761330.011
cell projection morphogenesisGO:00488581290.011
ion homeostasisGO:00508012300.011
organophosphate biosynthetic processGO:00904071630.011
myeloid cell differentiationGO:00300991170.011
negative regulation of phosphorylationGO:00423261740.011
snrna metabolic processGO:0016073150.011
negative regulation of cellular amine metabolic processGO:003323930.011
regulation of immune responseGO:00507762010.011
cell adhesionGO:00071553250.011
positive regulation of phosphorylationGO:00423273940.011
defense response to virusGO:0051607710.011
nucleoside monophosphate metabolic processGO:00091231910.011
mapk cascadeGO:00001652880.011
regulation of purine nucleotide catabolic processGO:00331212050.011
cell divisionGO:00513011680.011
endocytosisGO:00068971590.011
peripheral nervous system developmentGO:000742220.011
positive regulation of proteolysisGO:00458621420.011
secretion by cellGO:00329402260.011
positive regulation of cell differentiationGO:00455972110.011
organelle fissionGO:00482851490.010
regulation of cell morphogenesisGO:00226041530.010
response to cytokineGO:00340972320.010
biological adhesionGO:00226103310.010
regulation of cell migrationGO:00303342890.010
guanosine containing compound catabolic processGO:19010692390.010
regulation of dna metabolic processGO:00510521530.010
monocarboxylic acid metabolic processGO:00327871850.010
regulation of actin filament based processGO:00329701410.010
intrinsic apoptotic signaling pathwayGO:00971931270.010
negative regulation of protein maturationGO:19033181420.010
negative regulation of proteolysisGO:00458611320.010
cellular response to cytokine stimulusGO:00713451810.010
regulation of endopeptidase activityGO:00525481700.010
positive regulation of transferase activityGO:00513472270.010
chromosome segregationGO:00070591140.010
nucleic acid phosphodiester bond hydrolysisGO:00903051020.010
negative regulation of transferase activityGO:00513481240.010
dna conformation changeGO:00711031130.010
nuclear divisionGO:00002801280.010
gtp catabolic processGO:00061842370.010

SMPD4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.028
inherited metabolic disorderDOID:6552420.023
central nervous system diseaseDOID:3311860.015
nervous system diseaseDOID:8634310.015
musculoskeletal system diseaseDOID:172230.014
sensory system diseaseDOID:00501552030.014
disease of cellular proliferationDOID:145661740.011
cancerDOID:1621670.011
eye and adnexa diseaseDOID:14921500.011
organ system cancerDOID:00506861640.011