Homo sapiens

22 known processes

AKR1B1

aldo-keto reductase family 1, member B1 (aldose reductase)

(Aliases: ALR2,ADR,MGC1804,AR,ALDR1)

AKR1B1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to abiotic stimulusGO:00096283360.093
Rat
histone modificationGO:00165702510.086
chromatin modificationGO:00165682980.075
cellular amino acid metabolic processGO:00065201160.074
cellular ketone metabolic processGO:0042180800.072
methylationGO:00322591060.071
regulation of cellular amine metabolic processGO:0033238110.070
positive regulation of apoptotic processGO:00430652460.067
regulation of cell cycleGO:00517263930.063
positive regulation of programmed cell deathGO:00430682490.063
regulation of cellular amino acid metabolic processGO:000652160.061
positive regulation of cell deathGO:00109422630.061
regulation of mitotic cell cycleGO:00073461890.061
regulation of sequence specific dna binding transcription factor activityGO:00510902110.060
histone methylationGO:0016571600.055
chromatin organizationGO:00063253510.054
amine metabolic processGO:0009308440.054
protein alkylationGO:0008213740.053
macromolecule methylationGO:0043414970.052
cell developmentGO:00484683280.052
determination of adult lifespanGO:000834020.051
multicellular organismal agingGO:001025930.051
mitotic cell cycle phase transitionGO:00447721620.049
covalent chromatin modificationGO:00165692540.048
cellular amine metabolic processGO:0044106410.047
regulation of cell cycle processGO:00105642660.046
immune responseGO:00069553070.044
negative regulation of cell cycle phase transitionGO:1901988890.044
negative regulation of cell cycleGO:00457861930.044
negative regulation of nf kappab transcription factor activityGO:0032088510.044
defense responseGO:00069523150.043
protein methylationGO:0006479740.043
mitotic cell cycleGO:00002783260.043
regulation of mitotic cell cycle phase transitionGO:19019901180.043
post embryonic developmentGO:000979120.042
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.040
response to oxygen levelsGO:00704821000.039
locomotory behaviorGO:000762610.039
positive regulation of transportGO:00510503360.039
negative regulation of protein metabolic processGO:00512483910.038
cytoplasmic transportGO:00164823790.038
cellular lipid metabolic processGO:00442553030.038
Human
response to decreased oxygen levelsGO:0036293960.038
androgen receptor signaling pathwayGO:0030521340.038
cell cycle phase transitionGO:00447701730.037
oogenesisGO:004847720.036
negative regulation of mitotic cell cycle phase transitionGO:1901991850.036
cell growthGO:00160491600.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
cation transportGO:00068123310.035
female gamete generationGO:000729220.035
negative regulation of cell cycle processGO:00109481210.035
response to hypoxiaGO:0001666960.034
negative regulation of cellular protein metabolic processGO:00322693530.034
ribonucleoside catabolic processGO:00424544060.034
regulation of cell cycle phase transitionGO:19019871260.033
system processGO:00030083490.033
cell adhesionGO:00071553250.033
biological adhesionGO:00226103310.033
organophosphate catabolic processGO:00464344300.033
mitotic cell cycle processGO:19030472860.033
nucleoside triphosphate catabolic processGO:00091433940.032
oxidation reduction processGO:00551143960.032
cation transmembrane transportGO:00986552380.032
purine ribonucleoside metabolic processGO:00461284370.032
lipid metabolic processGO:00066293810.032
Human
positive regulation of cellular amine metabolic processGO:003324070.032
ribonucleoside triphosphate metabolic processGO:00091994120.032
nucleotide catabolic processGO:00091664080.032
signal transduction by phosphorylationGO:00230142970.032
intracellular receptor signaling pathwayGO:00305221040.031
regenerationGO:003109940.031
ion transmembrane transportGO:00342203380.031
positive regulation of cellular catabolic processGO:00313312840.030
actin filament based processGO:00300292240.030
response to oxygen containing compoundGO:19017003690.030
Human Rat
negative regulation of catalytic activityGO:00430863350.030
chemical homeostasisGO:00488783060.030
cell cycle g1 s phase transitionGO:0044843800.030
nucleoside triphosphate metabolic processGO:00091414220.029
apoptotic signaling pathwayGO:00971902680.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
purine nucleoside catabolic processGO:00061523980.028
g1 s transition of mitotic cell cycleGO:0000082780.028
negative regulation of cell proliferationGO:00082852280.028
carbohydrate metabolic processGO:00059752070.028
Rat
segmentationGO:003528240.028
purine ribonucleoside catabolic processGO:00461303980.028
regulation of transferase activityGO:00513383550.028
cellular macromolecule catabolic processGO:00442653800.028
positive regulation of catabolic processGO:00098963100.028
single organism cellular localizationGO:19025803320.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
response to other organismGO:00517072610.027
transmembrane transportGO:00550853990.027
cellular macromolecular complex assemblyGO:00346223240.027
small molecule biosynthetic processGO:00442831570.027
Human Rat
maintenance of locationGO:00512351120.027
negative regulation of phosphorus metabolic processGO:00105632670.027
neuromuscular junction developmentGO:000752830.027
regulation of mapk cascadeGO:00434082620.027
negative regulation of mitotic cell cycleGO:00459301020.027
regulation of kinase activityGO:00435493140.026
regulation of cellular ketone metabolic processGO:0010565500.026
purine nucleotide catabolic processGO:00061954050.026
purine ribonucleotide catabolic processGO:00091544040.026
single organism membrane organizationGO:00448022680.026
positive regulation of cellular component organizationGO:00511303760.026
intracellular steroid hormone receptor signaling pathwayGO:0030518610.026
ribonucleotide catabolic processGO:00092614050.025
regulation of proteolysisGO:00301622930.025
vesicle mediated transportGO:00161923710.025
inorganic ion transmembrane transportGO:00986602310.025
ras protein signal transductionGO:0007265730.025
single organism carbohydrate metabolic processGO:00447231930.025
Rat
protein catabolic processGO:00301633250.025
ion homeostasisGO:00508012300.024
positive regulation of hydrolase activityGO:00513453310.024
membrane organizationGO:00610242920.024
response to biotic stimulusGO:00096072760.024
regulation of cell differentiationGO:00455953930.024
protein maturationGO:00516042330.024
mapk cascadeGO:00001652880.024
negative regulation of programmed cell deathGO:00430693210.024
negative regulation of cell deathGO:00605483450.024
metal ion transportGO:00300012720.024
regulation of protein kinase activityGO:00458592890.023
regulation of cell cycle g1 s phase transitionGO:1902806420.023
regulation of locomotionGO:00400123290.023
protein processingGO:00164852260.023
cellular homeostasisGO:00197251960.023
regulation of anatomical structure morphogenesisGO:00226032860.023
positive regulation of immune system processGO:00026842830.023
positive regulation of protein phosphorylationGO:00019343130.022
monocarboxylic acid metabolic processGO:00327871850.022
Human
negative regulation of cellular amine metabolic processGO:003323930.022
regulation of establishment of protein localizationGO:00702012420.022
regulation of immune responseGO:00507762010.022
regulation of intracellular transportGO:00323861950.022
adult locomotory behaviorGO:000834410.022
regulation of nucleotide metabolic processGO:00061402690.022
intracellular protein transportGO:00068862700.022
regulation of cellular response to stressGO:00801352440.021
regulation of purine nucleotide metabolic processGO:19005422640.021
negative regulation of phosphate metabolic processGO:00459362670.021
cellular protein catabolic processGO:00442572610.021
protein localization to organelleGO:00333652800.021
inorganic cation transmembrane transportGO:00986621940.021
memoryGO:000761330.021
organonitrogen compound biosynthetic processGO:19015662000.021
dephosphorylationGO:00163112090.021
innate immune responseGO:00450871780.020
regulation of protein localizationGO:00328802960.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
regulation of transporter activityGO:0032409820.020
regulation of response to external stimulusGO:00321012220.020
cellular response to endogenous stimulusGO:00714953360.020
Human Rat
negative regulation of cell cycle g1 s phase transitionGO:1902807290.020
blastoderm segmentationGO:000735020.020
purine containing compound catabolic processGO:00725234110.020
lipid biosynthetic processGO:00086101770.020
Human
regulation of protein transportGO:00512232130.020
regulation of cell adhesionGO:00301551660.019
positive regulation of phosphorylationGO:00423273940.019
cell morphogenesisGO:00009022960.019
regulation of ion transportGO:00432691890.019
negative regulation of transportGO:00510511760.019
negative regulation of apoptotic processGO:00430663160.019
nitrogen compound transportGO:00717051910.019
negative regulation of phosphorylationGO:00423261740.019
negative regulation of cellular component organizationGO:00511292350.019
nervous system developmentGO:00073992930.019
Fly
histone arginine methylationGO:003496960.019
guanosine containing compound catabolic processGO:19010692390.019
oocyte differentiationGO:000999420.018
cellular protein complex assemblyGO:00436231880.018
proteasomal protein catabolic processGO:00104981760.018
cellular ion homeostasisGO:00068731680.018
organic acid biosynthetic processGO:0016053970.018
Human
negative regulation of protein modification processGO:00314002000.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
regulation of cell migrationGO:00303342890.018
cell projection organizationGO:00300302520.018
developmental cell growthGO:0048588180.018
regulation of protein maturationGO:19033171500.018
negative regulation of hydrolase activityGO:00513461820.018
response to external biotic stimulusGO:00432072610.018
oocyte developmentGO:004859910.018
negative regulation of multicellular organismal processGO:00512413170.018
cation homeostasisGO:00550801890.018
reactive oxygen species metabolic processGO:0072593750.017
ubiquitin dependent protein catabolic processGO:00065112060.017
gtp catabolic processGO:00061842370.017
carbohydrate derivative biosynthetic processGO:19011372070.017
cellular response to oxygen containing compoundGO:19017012760.017
Human Rat
rho protein signal transductionGO:0007266260.017
modification dependent protein catabolic processGO:00199412090.017
regulation of androgen receptor signaling pathwayGO:0060765180.017
regulation of cell motilityGO:20001452990.017
protein ubiquitinationGO:00165673140.017
regulation of cytokine productionGO:00018172320.017
regulation of cytoplasmic transportGO:19036491490.017
endomembrane system organizationGO:00102561960.017
cellular cation homeostasisGO:00300031630.017
neurotransmitter secretionGO:000726940.017
morphogenesis of embryonic epitheliumGO:001633140.017
microtubule based processGO:00070172100.017
cytokine productionGO:00018162470.017
regulation of transmembrane transportGO:00347621390.017
sulfur compound metabolic processGO:00067901010.017
response to lipidGO:00339932060.016
Human
carboxylic acid biosynthetic processGO:0046394970.016
Human
cellular chemical homeostasisGO:00550821800.016
negative regulation of intracellular signal transductionGO:19025321830.016
negative regulation of protein processingGO:00109551420.016
regulation of nucleoside metabolic processGO:00091182090.016
positive regulation of transferase activityGO:00513472270.016
posttranscriptional regulation of gene expressionGO:00106082130.016
divalent metal ion transportGO:00708381520.016
sequestering of metal ionGO:0051238240.016
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.016
regulation of protein processingGO:00706131500.016
motor neuron axon guidanceGO:000804520.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
intrinsic apoptotic signaling pathwayGO:00971931270.016
peripheral nervous system developmentGO:000742220.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
negative regulation of protein maturationGO:19033181420.016
regulation of cellular component biogenesisGO:00440872810.016
divalent inorganic cation transportGO:00725111580.016
organic hydroxy compound metabolic processGO:19016151470.016
Human Rat
actin cytoskeleton organizationGO:00300362070.015
positive regulation of synaptic transmissionGO:005080640.015
sequestering of calcium ionGO:0051208170.015
positive regulation of mapk cascadeGO:00434101900.015
regulation of purine nucleotide catabolic processGO:00331212050.015
nucleoside catabolic processGO:00091644080.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
syncytium formation by plasma membrane fusionGO:000076820.015
neurological system processGO:00508771630.015
positive regulation of nucleotide catabolic processGO:00308131850.015
regulation of apoptotic signaling pathwayGO:20012331750.015
organelle assemblyGO:00709251760.015
regulation of peptidase activityGO:00525471800.015
cell activationGO:00017752130.015
regulation of protein catabolic processGO:00421761550.015
nucleoside phosphate catabolic processGO:19012924120.015
cardiac muscle cell contractionGO:008600340.015
compound eye developmentGO:004874910.015
regulation of synaptic plasticityGO:004816730.015
response to axon injuryGO:004867810.015
regulation of nucleotide catabolic processGO:00308112050.015
single organism cell adhesionGO:00986021790.015
protein targetingGO:00066051870.015
negative regulation of protein phosphorylationGO:00019331400.015
divalent inorganic cation homeostasisGO:00725071360.015
regulation of secretionGO:00510461940.015
reactive oxygen species biosynthetic processGO:190340940.015
rhythmic behaviorGO:000762220.015
regulation of protein serine threonine kinase activityGO:00719001790.015
multi organism cellular processGO:00447641560.015
actin filament based movementGO:0030048170.015
metal ion homeostasisGO:00550651690.015
regulation of ion transmembrane transportGO:00347651320.014
guanosine containing compound metabolic processGO:19010682440.014
regulation of cell morphogenesisGO:00226041530.014
regulation of metal ion transportGO:00109591200.014
negative regulation of transferase activityGO:00513481240.014
regulation of transmembrane transporter activityGO:0022898740.014
regulation of growthGO:00400081650.014
regulation of secretion by cellGO:19035301770.014
circadian behaviorGO:004851220.014
negative regulation of proteolysisGO:00458611320.014
cellular amide metabolic processGO:0043603690.014
inner ear morphogenesisGO:004247240.014
embryonic epithelial tube formationGO:000183840.014
fatty acid metabolic processGO:00066311150.014
Human
cellular modified amino acid metabolic processGO:0006575640.014
response to bacteriumGO:00096171440.014
positive regulation of cell adhesionGO:0045785840.014
associative learningGO:000830610.014
spermatid developmentGO:000728640.014
monovalent inorganic cation transportGO:00156721280.014
anterior posterior axis specificationGO:000994820.014
tissue regenerationGO:004224630.014
nerve developmentGO:002167540.014
actin mediated cell contractionGO:0070252120.014
growthGO:00400072020.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of cellular component movementGO:00512703340.014
purine ribonucleoside triphosphate catabolic processGO:00092073910.014
secretionGO:00469032540.014
metencephalon developmentGO:002203720.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
secretion by cellGO:00329402260.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
response to woundingGO:00096111680.013
mitochondrion organizationGO:00070051560.013
positive regulation of nucleoside metabolic processGO:00459791860.013
positive regulation of cell proliferationGO:00082843010.013
Human Rat
hemopoiesisGO:00300971800.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
wnt signaling pathwayGO:00160551560.013
positive regulation of kinase activityGO:00336742040.013
regulation of gtp catabolic processGO:00331241800.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
protein localization to membraneGO:00726571600.013
lipid localizationGO:00108761060.013
neuron projection regenerationGO:003110210.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of neural precursor cell proliferationGO:200017740.013
regulation of vesicle mediated transportGO:00606271300.013
positive regulation of protein kinase activityGO:00458601900.013
regulation of ion transmembrane transporter activityGO:0032412720.013
atp metabolic processGO:00460341760.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
interspecies interaction between organismsGO:00444191560.013
response to inorganic substanceGO:00100351270.013
Rat
monocarboxylic acid biosynthetic processGO:0072330670.013
Human
limbic system developmentGO:002176130.013
regulation of endopeptidase activityGO:00525481700.013
rna interferenceGO:001624640.013
spermatid differentiationGO:004851540.013
positive regulation of locomotionGO:00400171860.013
myoblast fusionGO:000752010.013
regulation of meiotic cell cycleGO:005144540.013
defense response to bacteriumGO:0042742630.013
tripartite regional subdivisionGO:000735120.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
glutathione metabolic processGO:0006749200.013
nucleoside monophosphate metabolic processGO:00091231910.013
cell substrate adhesionGO:00315891320.013
peptidyl tyrosine phosphorylationGO:00181081700.013
positive regulation of organelle organizationGO:00106381950.013
immune system developmentGO:00025201950.013
immune effector processGO:00022521590.013
developmental growthGO:0048589480.013
cofactor metabolic processGO:0051186870.013
visual behaviorGO:000763220.013
small gtpase mediated signal transductionGO:0007264780.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
organ formationGO:004864530.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of cell growthGO:00015581350.013
nuclear transportGO:00511691790.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
response to virusGO:00096151260.013
anatomical structure formation involved in morphogenesisGO:00486462840.012
microtubule cytoskeleton organizationGO:00002261760.012
protein modification by small protein conjugationGO:00324463420.012
viral processGO:00160321460.012
matingGO:000761810.012
organophosphate biosynthetic processGO:00904071630.012
regulation of multi organism processGO:00439001570.012
small molecule catabolic processGO:0044282920.012
Human
establishment of protein localization to organelleGO:00725941720.012
anterior posterior axis specification embryoGO:000859520.012
peptidyl tyrosine modificationGO:00182121700.012
negative regulation of developmental processGO:00510932470.012
cell divisionGO:00513011680.012
regulation of cytoskeleton organizationGO:00514931770.012
calcium ion transportGO:00068161470.012
single organismal cell cell adhesionGO:00163371480.012
defense response to other organismGO:00985421290.012
anion transportGO:00068201610.012
epithelium developmentGO:00604292270.012
Human
cellular component morphogenesisGO:00329893140.012
cellular metal ion homeostasisGO:00068751460.012
response to metal ionGO:0010038840.012
autophagyGO:0006914880.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
positive regulation of protein transportGO:00512221350.012
negative regulation of immune system processGO:00026831360.012
protein oligomerizationGO:00512591730.012
Human
somatic muscle developmentGO:000752510.012
cellular response to glucocorticoid stimulusGO:007138540.012
cell part morphogenesisGO:00329901370.012
positive regulation of developmental processGO:00510943140.012
calcium ion transmembrane transportGO:0070588760.012
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.012
glycoprotein metabolic processGO:00091001100.012
positive regulation of ion transportGO:0043270870.012
endocytosisGO:00068971590.012
endosomal transportGO:00161971290.012
neuroblast proliferationGO:000740540.012
plasma membrane organizationGO:00070091150.011
hindbrain developmentGO:003090230.011
wound healingGO:00420601150.011
glial cell migrationGO:000834740.011
positive regulation of gtp catabolic processGO:00331261660.011
retinoic acid biosynthetic processGO:000213820.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
reactive nitrogen species metabolic processGO:200105730.011
regulation of ion homeostasisGO:2000021730.011
positive regulation of immune responseGO:00507781590.011
testosterone biosynthetic processGO:006137020.011
cell type specific apoptotic processGO:00972851250.011
startle responseGO:000196430.011
positive regulation of proteolysisGO:00458621420.011
cell projection assemblyGO:00300311260.011
mesodermal cell fate commitmentGO:000171020.011
response to nitrogen compoundGO:19016981840.011
Rat
hematopoietic or lymphoid organ developmentGO:00485341860.011
positive regulation of gliogenesisGO:001401540.011
response to fungusGO:000962040.011
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.011
glycosyl compound catabolic processGO:19016584130.011
myosin filament assemblyGO:003103420.011
sodium ion transmembrane transportGO:0035725590.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
sex determinationGO:000753030.011
photoreceptor cell differentiationGO:004653020.011
stem cell divisionGO:001714520.011
negative regulation of kinase activityGO:00336731060.011
protein homooligomerizationGO:00512601000.011
Human
rna processingGO:00063962550.011
visual learningGO:000854210.011
developmental programmed cell deathGO:001062330.011
thymus developmentGO:004853830.011
neural crest cell developmentGO:001403230.011
establishment of protein localization to membraneGO:00901501210.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
protein autophosphorylationGO:00467771230.011
morphogenesis of a polarized epitheliumGO:000173830.011
atp catabolic processGO:00062001570.011
regulation of intracellular protein transportGO:00331571230.011
regulation of membrane potentialGO:0042391950.011
regulation of neurotransmitter secretionGO:004692830.011
response to cytokineGO:00340972320.011
regulation of transcription during mitosisGO:004589620.011
taxisGO:00423301570.011
negative regulation of protein kinase activityGO:0006469980.011
cellular response to organic cyclic compoundGO:00714071270.011
striated muscle contractionGO:0006941520.011
cell migration involved in gastrulationGO:004207410.011
striated muscle myosin thick filament assemblyGO:007168820.011
somatic stem cell maintenanceGO:003501940.011
prostate gland developmentGO:003085030.011
peptidyl serine modificationGO:00182091060.011
protein localization to nucleusGO:00345041360.011
phospholipid metabolic processGO:0006644990.011
response to hormoneGO:00097251750.011
Human Rat
vasculature developmentGO:00019441810.011
convergent extensionGO:006002610.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
protein o linked glycosylation via serineGO:001824230.011
ribonucleoside triphosphate catabolic processGO:00092033910.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
negative regulation of organelle organizationGO:00106391260.011
response to organonitrogen compoundGO:00102431560.011
Rat
sensory perception of painGO:001923340.011
salivary gland morphogenesisGO:000743540.011
ameboidal type cell migrationGO:00016671350.010
axon regenerationGO:003110310.010
sleepGO:003043120.010
neural tube formationGO:000184130.010
positive regulation of cell motilityGO:20001471770.010
negative regulation of catabolic processGO:00098951040.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
regulation of dna metabolic processGO:00510521530.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
nucleoside monophosphate catabolic processGO:00091251590.010
atrioventricular valve developmentGO:000317130.010
regulation of protein complex assemblyGO:00432541470.010
cellular calcium ion homeostasisGO:00068741170.010
cellular response to lipidGO:00713961270.010
melanin metabolic processGO:000658210.010
activation of immune responseGO:00022531140.010

AKR1B1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.035
nervous system diseaseDOID:8634310.035
disease of metabolismDOID:00146672950.028
Human
sensory system diseaseDOID:00501552030.027
musculoskeletal system diseaseDOID:172230.025
inherited metabolic disorderDOID:6552420.023
Human
immune system diseaseDOID:29141550.019
eye and adnexa diseaseDOID:14921500.019
eye diseaseDOID:56141490.018
neurodegenerative diseaseDOID:12891020.018
muscular diseaseDOID:00800001140.016
muscle tissue diseaseDOID:661130.016
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.016
organ system cancerDOID:00506861640.015
myopathyDOID:4231040.015
connective tissue diseaseDOID:651090.015
brain diseaseDOID:936730.015
cardiovascular system diseaseDOID:12871060.014
retinal diseaseDOID:56791180.014
bone diseaseDOID:0080001880.014
disease of mental healthDOID:150700.012
retinal degenerationDOID:8466890.011
hematopoietic system diseaseDOID:741000.011