Homo sapiens

15 known processes

HFE2

hemochromatosis type 2 (juvenile)

(Aliases: HFE2A,MGC23953,HJV,JH,RGMC)

HFE2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030083490.061
post embryonic developmentGO:000979120.057
cellular amino acid metabolic processGO:00065201160.055
muscle contractionGO:0006936730.052
cellular ketone metabolic processGO:0042180800.052
regulation of cellular amino acid metabolic processGO:000652160.040
regulation of cellular ketone metabolic processGO:0010565500.040
regulation of cellular amine metabolic processGO:0033238110.040
cellular amine metabolic processGO:0044106410.039
amine metabolic processGO:0009308440.039
lipid metabolic processGO:00066293810.039
cytoplasmic transportGO:00164823790.037
actin filament based processGO:00300292240.036
metal ion transportGO:00300012720.036
positive regulation of cellular amino acid metabolic processGO:004576430.035
muscle system processGO:0003012810.034
multicellular organismal agingGO:001025930.033
organophosphate catabolic processGO:00464344300.033
positive regulation of cellular amine metabolic processGO:003324070.032
chemical homeostasisGO:00488783060.032
female gamete generationGO:000729220.031
determination of adult lifespanGO:000834020.031
purine ribonucleoside triphosphate metabolic processGO:00092054110.031
immune responseGO:00069553070.031
single organism cellular localizationGO:19025803320.031
segmentationGO:003528240.030
negative regulation of catalytic activityGO:00430863350.030
cation transportGO:00068123310.030
purine containing compound catabolic processGO:00725234110.030
single organism membrane organizationGO:00448022680.030
oogenesisGO:004847720.029
purine ribonucleoside metabolic processGO:00461284370.029
negative regulation of protein metabolic processGO:00512483910.029
nucleoside triphosphate metabolic processGO:00091414220.028
transmembrane transportGO:00550853990.028
nucleotide catabolic processGO:00091664080.028
protein modification by small protein conjugationGO:00324463420.028
oxidation reduction processGO:00551143960.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
small molecule biosynthetic processGO:00442831570.027
negative regulation of cellular protein metabolic processGO:00322693530.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
positive regulation of phosphorylationGO:00423273940.027
cellular component morphogenesisGO:00329893140.027
cellular lipid metabolic processGO:00442553030.026
protein localization to organelleGO:00333652800.026
purine ribonucleotide catabolic processGO:00091544040.026
ribonucleoside catabolic processGO:00424544060.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
striated muscle contractionGO:0006941520.026
locomotory behaviorGO:000762610.026
intracellular protein transportGO:00068862700.026
glycosyl compound catabolic processGO:19016584130.026
monocarboxylic acid metabolic processGO:00327871850.026
circulatory system processGO:00030131130.026
nucleoside phosphate catabolic processGO:19012924120.026
purine nucleoside triphosphate metabolic processGO:00091444120.026
response to abiotic stimulusGO:00096283360.025
cellular macromolecule catabolic processGO:00442653800.025
regenerationGO:003109940.025
purine nucleotide catabolic processGO:00061954050.025
positive regulation of catabolic processGO:00098963100.025
negative regulation of phosphorus metabolic processGO:00105632670.025
nucleoside catabolic processGO:00091644080.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
nucleoside triphosphate catabolic processGO:00091433940.024
blood circulationGO:00080151130.024
protein ubiquitinationGO:00165673140.024
ion homeostasisGO:00508012300.024
purine nucleoside catabolic processGO:00061523980.024
negative regulation of cell deathGO:00605483450.024
actin filament based movementGO:0030048170.024
negative regulation of phosphate metabolic processGO:00459362670.024
cellular response to endogenous stimulusGO:00714953360.024
cellular macromolecular complex assemblyGO:00346223240.023
circulatory system developmentGO:00723592620.023
purine ribonucleoside catabolic processGO:00461303980.023
ion transmembrane transportGO:00342203380.023
positive regulation of transportGO:00510503360.023
single organism carbohydrate metabolic processGO:00447231930.023
regulation of transferase activityGO:00513383550.023
protein catabolic processGO:00301633250.023
regulation of protein localizationGO:00328802960.023
neuromuscular junction developmentGO:000752830.023
cellular protein catabolic processGO:00442572610.023
positive regulation of cellular component organizationGO:00511303760.023
regulation of anatomical structure morphogenesisGO:00226032860.022
regulation of cellular component movementGO:00512703340.022
hindbrain developmentGO:003090230.022
positive regulation of hydrolase activityGO:00513453310.022
anatomical structure formation involved in morphogenesisGO:00486462840.022
membrane organizationGO:00610242920.022
mapk cascadeGO:00001652880.022
response to organic cyclic compoundGO:00140702040.022
carbohydrate metabolic processGO:00059752070.022
cardiovascular system developmentGO:00723582620.021
organonitrogen compound biosynthetic processGO:19015662000.021
regulation of kinase activityGO:00435493140.021
vesicle mediated transportGO:00161923710.021
ribonucleotide catabolic processGO:00092614050.021
inorganic cation transmembrane transportGO:00986621940.021
signal transduction by phosphorylationGO:00230142970.021
reactive oxygen species biosynthetic processGO:190340940.021
negative regulation of programmed cell deathGO:00430693210.021
cell developmentGO:00484683280.021
cation transmembrane transportGO:00986552380.021
morphogenesis of embryonic epitheliumGO:001633140.021
response to oxygen containing compoundGO:19017003690.021
protein targetingGO:00066051870.021
nucleoside monophosphate metabolic processGO:00091231910.020
biological adhesionGO:00226103310.020
nucleoside monophosphate catabolic processGO:00091251590.020
protein maturationGO:00516042330.020
negative regulation of protein modification processGO:00314002000.020
defense responseGO:00069523150.020
purine nucleoside monophosphate metabolic processGO:00091261860.020
purine ribonucleoside monophosphate metabolic processGO:00091671860.020
negative regulation of cellular component organizationGO:00511292350.020
apoptotic signaling pathwayGO:00971902680.020
cardiac muscle cell contractionGO:008600340.020
regulation of nucleotide metabolic processGO:00061402690.020
cell morphogenesisGO:00009022960.020
inorganic ion transmembrane transportGO:00986602310.020
actin mediated cell contractionGO:0070252120.020
purine ribonucleoside monophosphate catabolic processGO:00091691580.020
regulation of cellular response to stressGO:00801352440.020
positive regulation of developmental processGO:00510943140.020
regulation of proteolysisGO:00301622930.019
regulation of cell cycleGO:00517263930.019
blastoderm segmentationGO:000735020.019
regulation of mapk cascadeGO:00434082620.019
positive regulation of cellular catabolic processGO:00313312840.019
organ formationGO:004864530.019
cellular response to dna damage stimulusGO:00069743790.019
regulation of establishment of protein localizationGO:00702012420.019
negative regulation of apoptotic processGO:00430663160.019
regulation of protein transportGO:00512232130.019
maintenance of locationGO:00512351120.019
regulation of cellular component biogenesisGO:00440872810.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
ras protein signal transductionGO:0007265730.018
reactive nitrogen species metabolic processGO:200105730.018
cellular chemical homeostasisGO:00550821800.018
dephosphorylationGO:00163112090.018
ribonucleoside monophosphate metabolic processGO:00091611870.018
cellular homeostasisGO:00197251960.018
organic hydroxy compound metabolic processGO:19016151470.018
cellular response to oxygen containing compoundGO:19017012760.018
purine nucleoside monophosphate catabolic processGO:00091281580.018
innate immune responseGO:00450871780.018
positive regulation of protein phosphorylationGO:00019343130.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of intracellular transportGO:00323861950.018
organelle assemblyGO:00709251760.018
cell adhesionGO:00071553250.018
syncytium formation by plasma membrane fusionGO:000076820.018
cellular protein complex assemblyGO:00436231880.017
endomembrane system organizationGO:00102561960.017
ribonucleoside monophosphate catabolic processGO:00091581580.017
atp metabolic processGO:00460341760.017
organic acid biosynthetic processGO:0016053970.017
response to biotic stimulusGO:00096072760.017
carboxylic acid biosynthetic processGO:0046394970.017
small gtpase mediated signal transductionGO:0007264780.017
negative regulation of transportGO:00510511760.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
mitotic cell cycleGO:00002783260.017
negative regulation of intracellular signal transductionGO:19025321830.017
response to external biotic stimulusGO:00432072610.017
embryonic epithelial tube formationGO:000183840.017
regulation of cell differentiationGO:00455953930.017
response to other organismGO:00517072610.017
metal ion homeostasisGO:00550651690.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
modification dependent macromolecule catabolic processGO:00436322120.017
epithelium developmentGO:00604292270.017
cellular ion homeostasisGO:00068731680.017
regulation of cell cycle processGO:00105642660.017
memoryGO:000761330.017
nervous system developmentGO:00073992930.016
negative regulation of hydrolase activityGO:00513461820.016
regulation of protein kinase activityGO:00458592890.016
cell projection organizationGO:00300302520.016
reactive oxygen species metabolic processGO:0072593750.016
proteasomal protein catabolic processGO:00104981760.016
spermatid differentiationGO:004851540.016
regulation of ion transportGO:00432691890.016
adult locomotory behaviorGO:000834410.016
response to hormoneGO:00097251750.016
protein processingGO:00164852260.016
establishment of protein localization to organelleGO:00725941720.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
protein localization to membraneGO:00726571600.016
tissue regenerationGO:004224630.016
oocyte developmentGO:004859910.016
calcium ion transportGO:00068161470.016
regulation of cytokine productionGO:00018172320.016
lipid biosynthetic processGO:00086101770.016
positive regulation of apoptotic processGO:00430652460.016
mitotic cell cycle processGO:19030472860.016
response to activityGO:001482300.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
rhythmic behaviorGO:000762220.015
atp catabolic processGO:00062001570.015
regulation of purine nucleotide metabolic processGO:19005422640.015
growthGO:00400072020.015
actin cytoskeleton organizationGO:00300362070.015
divalent metal ion transportGO:00708381520.015
nucleocytoplasmic transportGO:00069131760.015
fatty acid metabolic processGO:00066311150.015
negative regulation of phosphorylationGO:00423261740.015
cell fate determinationGO:000170930.015
inner ear morphogenesisGO:004247240.015
cell growthGO:00160491600.015
positive regulation of nucleotide metabolic processGO:00459812300.015
rna processingGO:00063962550.015
anterior posterior axis specificationGO:000994820.015
cardiac muscle contractionGO:0060048340.015
regulation of nucleoside metabolic processGO:00091182090.015
anterior posterior axis specification embryoGO:000859520.015
cation homeostasisGO:00550801890.015
modification dependent protein catabolic processGO:00199412090.015
positive regulation of cell deathGO:00109422630.015
response to fungusGO:000962040.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
rho protein signal transductionGO:0007266260.015
chromatin modificationGO:00165682980.015
carbohydrate derivative biosynthetic processGO:19011372070.015
ubiquitin dependent protein catabolic processGO:00065112060.015
divalent inorganic cation transportGO:00725111580.015
oocyte differentiationGO:000999420.015
regulation of locomotionGO:00400123290.015
circadian behaviorGO:004851220.015
myoblast fusionGO:000752010.015
cofactor metabolic processGO:0051186870.015
microtubule based processGO:00070172100.015
compound eye developmentGO:004874910.015
spermatid developmentGO:000728640.014
cellular cation homeostasisGO:00300031630.014
tripartite regional subdivisionGO:000735120.014
regulation of membrane potentialGO:0042391950.014
negative regulation of multicellular organismal processGO:00512413170.014
regulation of cell motilityGO:20001452990.014
posttranscriptional regulation of gene expressionGO:00106082130.014
positive regulation of immune system processGO:00026842830.014
regulation of protein maturationGO:19033171500.014
regulation of transmembrane transportGO:00347621390.014
regulation of cytoskeleton organizationGO:00514931770.014
response to nitrogen compoundGO:19016981840.014
regulation of nucleotide catabolic processGO:00308112050.014
regulation of response to external stimulusGO:00321012220.014
photoreceptor cell differentiationGO:004653020.014
muscle structure developmentGO:0061061980.014
nuclear transportGO:00511691790.014
chromatin organizationGO:00063253510.014
regulation of hormone levelsGO:00108171250.014
regulation of protein catabolic processGO:00421761550.014
regulation of purine nucleotide catabolic processGO:00331212050.014
divalent inorganic cation homeostasisGO:00725071360.014
positive regulation of cell proliferationGO:00082843010.014
regulation of immune responseGO:00507762010.014
somatic muscle developmentGO:000752510.014
regulation of reactive oxygen species metabolic processGO:2000377410.013
positive regulation of transferase activityGO:00513472270.013
neural tube formationGO:000184130.013
response to cytokineGO:00340972320.013
nerve developmentGO:002167540.013
organophosphate biosynthetic processGO:00904071630.013
response to inorganic substanceGO:00100351270.013
regulation of system processGO:00440571010.013
regulation of cytoplasmic transportGO:19036491490.013
response to lipidGO:00339932060.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
somitogenesisGO:000175620.013
tube closureGO:006060630.013
regulation of neural precursor cell proliferationGO:200017740.013
limbic system developmentGO:002176130.013
positive regulation of cell differentiationGO:00455972110.013
tissue morphogenesisGO:0048729960.013
cytokine productionGO:00018162470.013
response to axon injuryGO:004867810.013
regulation of multi organism processGO:00439001570.013
regulation of endopeptidase activityGO:00525481700.013
regulation of growthGO:00400081650.013
negative regulation of organelle organizationGO:00106391260.013
alcohol metabolic processGO:00060661140.013
positive regulation of protein transportGO:00512221350.013
positive regulation of programmed cell deathGO:00430682490.013
multi organism cellular processGO:00447641560.013
negative regulation of cell proliferationGO:00082852280.013
nitrogen compound transportGO:00717051910.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of apoptotic signaling pathwayGO:20012331750.013
monovalent inorganic cation transportGO:00156721280.013
cellular metal ion homeostasisGO:00068751460.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
negative regulation of protein phosphorylationGO:00019331400.012
cellular response to cytokine stimulusGO:00713451810.012
viral processGO:00160321460.012
fatty acid omega oxidationGO:001043020.012
histone modificationGO:00165702510.012
establishment of protein localization to membraneGO:00901501210.012
protein localization to nucleusGO:00345041360.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
cellular response to organic cyclic compoundGO:00714071270.012
interspecies interaction between organismsGO:00444191560.012
dna repairGO:00062811980.012
regulation of protein serine threonine kinase activityGO:00719001790.012
positive regulation of proteolysisGO:00458621420.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
regulation of ion transmembrane transportGO:00347651320.012
coenzyme metabolic processGO:0006732650.012
muscle cell differentiationGO:0042692630.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
visual behaviorGO:000763220.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
negative regulation of transferase activityGO:00513481240.012
secretion by cellGO:00329402260.012
wnt signaling pathwayGO:00160551560.012
negative regulation of protein processingGO:00109551420.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
negative regulation of cell cycleGO:00457861930.012
sequestering of metal ionGO:0051238240.012
regulation of protein processingGO:00706131500.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
regulation of secretionGO:00510461940.012
negative regulation of catabolic processGO:00098951040.012
regulation of intracellular protein transportGO:00331571230.011
detection of stimulusGO:0051606850.011
heart developmentGO:0007507950.011
negative regulation of protein maturationGO:19033181420.011
peripheral nervous system developmentGO:000742220.011
cellular component assembly involved in morphogenesisGO:0010927730.011
primary neural tube formationGO:001402030.011
regulation of cell growthGO:00015581350.011
cellular response to lipidGO:00713961270.011
cell cycle phase transitionGO:00447701730.011
regulation of protein complex assemblyGO:00432541470.011
sodium ion transmembrane transportGO:0035725590.011
matingGO:000761810.011
alpha amino acid metabolic processGO:1901605720.011
microtubule cytoskeleton organizationGO:00002261760.011
striated muscle tissue developmentGO:0014706590.011
defense response to fungusGO:005083240.011
positive regulation of kinase activityGO:00336742040.011
small molecule catabolic processGO:0044282920.011
organ morphogenesisGO:00098871470.011
sequestering of calcium ionGO:0051208170.011
positive regulation of organelle organizationGO:00106381950.011
positive regulation of nucleotide catabolic processGO:00308131850.011
cellular response to hormone stimulusGO:00328701250.011
viral life cycleGO:00190581320.011
protein acylationGO:00435431380.011
cellular response to external stimulusGO:00714961110.011
covalent chromatin modificationGO:00165692540.011
rna splicingGO:00083801310.011
cell projection assemblyGO:00300311260.011
regulation of actin filament based processGO:00329701410.011
nuclear importGO:00511701060.011
skeletal muscle contractionGO:0003009160.011
regulation of ion transmembrane transporter activityGO:0032412720.011
calcium ion homeostasisGO:00550741220.011
regulation of cell morphogenesisGO:00226041530.011
neural tube closureGO:000184330.011
associative learningGO:000830610.011
positive regulation of cellular component movementGO:00512721810.011
cell part morphogenesisGO:00329901370.011
metencephalon developmentGO:002203720.011
lipid catabolic processGO:0016042840.011
cell divisionGO:00513011680.011
motor neuron axon guidanceGO:000804520.011
heart contractionGO:0060047620.011
regulation of cell developmentGO:00602841610.011
blood vessel developmentGO:00015681720.011
positive regulation of cellular component biogenesisGO:00440891580.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
positive regulation of cytokine productionGO:00018191670.011
protein oligomerizationGO:00512591730.011
myosin filament assemblyGO:003103420.011
cellular calcium ion homeostasisGO:00068741170.011
negative regulation of cellular catabolic processGO:0031330830.010
neurological system processGO:00508771630.010
forebrain generation of neuronsGO:002187230.010
regulation of cell adhesionGO:00301551660.010
protein importGO:00170381300.010
response to virusGO:00096151260.010
vasculature developmentGO:00019441810.010
regulation of metal ion transportGO:00109591200.010
lipid localizationGO:00108761060.010
cellular response to nitrogen compoundGO:19016991440.010
response to metal ionGO:0010038840.010
negative regulation of locomotionGO:00400131180.010
regulation of peptidase activityGO:00525471800.010
regulation of homeostatic processGO:00328441210.010
behavioral response to ethanolGO:004814920.010
heart formationGO:006091420.010
striated muscle adaptationGO:001488840.010
morphogenesis of a polarized epitheliumGO:000173830.010
neuroblast proliferationGO:000740540.010
regulation of defense responseGO:00313471540.010
activation of immune responseGO:00022531140.010
guanosine containing compound catabolic processGO:19010692390.010
striated muscle myosin thick filament assemblyGO:007168820.010
regulation of viral processGO:00507921030.010
prostate gland developmentGO:003085030.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
establishment or maintenance of apical basal cell polarityGO:003508820.010
plasma membrane organizationGO:00070091150.010

HFE2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.071
muscle tissue diseaseDOID:661130.056
muscular diseaseDOID:00800001140.056
myopathyDOID:4231040.045
cardiovascular system diseaseDOID:12871060.034
disease of metabolismDOID:00146672950.029
sensory system diseaseDOID:00501552030.028
nervous system diseaseDOID:8634310.028
inherited metabolic disorderDOID:6552420.021
heart diseaseDOID:114680.021
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016
cardiomyopathyDOID:0050700500.015
intrinsic cardiomyopathyDOID:0060036500.015
disease of cellular proliferationDOID:145661740.015
retinal diseaseDOID:56791180.015
central nervous system diseaseDOID:3311860.015
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
immune system diseaseDOID:29141550.012
neurodegenerative diseaseDOID:12891020.011
retinal degenerationDOID:8466890.010
metal metabolism disorderDOID:896190.010
hematopoietic system diseaseDOID:741000.010
hemochromatosisDOID:235260.001